The targeting of anionized polyvinylpyrrolidone to the renal system

Biomaterials

Volumn 25, Issue 18, 2004, Pages 4309-4315

  Kodaira, Hiroshi ^a   Tsutsumi, Yasuo ^a   Yoshioka, Yasuo ^a   Kamada, Haruhiko ^a   Kaneda, Yoshihisa ^a   Yamamoto, Yoko ^a   Tsunoda, Shin Ichi ^a   Okamoto, Takayuki ^a   Mukai, Yohei ^a   Shibata, Hiroko ^a   Nakagawa, Shinsaku ^a   Mayumi, Tadanori ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Bioconjugation; Drug carrier; Polyvinylpyrrolidone (PVP); Renal targeting

Indexed keywords

BIOLOGICAL ORGANS; CARBOXYLATION; CARBOXYLIC ACIDS; CELLS; COPOLYMERS; DRUG PRODUCTS;

EPITHELIAL CELLS;

BIOMATERIALS;

1 VINYL 2 PYRROLIDINONE; ANION; DRUG CARRIER; MALEIC ACID; POLYMER; POVIDONE; POVIDONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXYLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SELECTIVITY; DRUG TARGETING; ENDOTHELIUM CELL; IN VIVO STUDY; IONIZATION; KIDNEY CELL; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REACTION OPTIMIZATION; SULFONATION; URINARY EXCRETION;

ANIMALS; ANIONS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; ENDOTHELIAL CELLS; HUMANS; INJECTIONS, INTRAVENOUS; KIDNEY; KIDNEY TUBULES; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED A; ORGAN SPECIFICITY; POVIDONE; SARCOMA;

EID: 12144287593     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2003.10.097     Document Type: Article

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