Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma

Science Translational Medicine

Volumn 5, Issue 209, 2013, Pages

  Jensen, Samuel A ^a   Day, Emily S ^b,c   Ko, Caroline H ^b,c   Hurley, Lisa A ^a   Luciano, Janina P ^a   Kouri, Fotini M ^a   Merkel, Timothy J ^b,c   Luthi, Andrea C ^b,c   Patel, Pinal C ^b,c   Cutler, Joshua I ^b,c   Daniel, Weston L ^b,c   Scott, Alexander W ^c,d   Rotz, Matthew W ^b   Meade, Thomas J ^b   Giljohann, David A ^b,c   Mirkin, Chad A ^b,c   Stegh, Alexander H ^a,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d Northwestern University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCL2LIKE12 PROTEIN; EFFECTOR CASPASE; GOLD NANOPARTICLE; MESSENGER RNA; NANOCONJUGATE; NUCLEIC ACID; ONCOPROTEIN; SMALL INTERFERING RNA; SPHERICAL NUCLEIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BCL2L12 GENE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG PENETRATION; GLIA CELL; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; MOUSE; NANOMEDICINE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; TISSUE DISTRIBUTION; TUMOR REGRESSION; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GLIOBLASTOMA; HUMANS; MICE; MICE, SCID; MUSCLE PROTEINS; NANOPARTICLES; NUCLEIC ACIDS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84890099118     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006839     Document Type: Article

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