Enhanced accumulation of low-molecular-weight chitosan in kidneys: A study on the influence of N-acetylation of chitosan on the renal targeting

Journal of Drug Targeting

Volumn 19, Issue 7, 2011, Pages 540-551

  Yuan, Zhi Xiang ^a,b   Li, Jing Jing ^a   Zhu, Di ^a   Sun, Xun ^a   Gong, Tao ^a   Zhang, Zhi Rong ^a  

^a SICHUAN UNIVERSITY   (China)

^b Sichuan Academy of Chinese Medicine Sciences   (China)

Author keywords

Amino group; Hydroxyethyl chitosan; Low molecular weight chitosan; N acetylation; Renal targeting

Indexed keywords

CHITOSAN; HYDROXYETHYL CHITOSAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG ACETYLATION; DRUG EXCRETION; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; URINARY EXCRETION;

ACETYLATION; ANIMALS; AREA UNDER CURVE; CARBOHYDRATE SEQUENCE; CELL LINE; CHITOSAN; DOGS; KIDNEY; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; TISSUE DISTRIBUTION;

EID: 79960496422     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2010.521158     Document Type: Article

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