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Volumn 109, Issue 8, 2012, Pages 3137-3142

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane

Author keywords

Glomerulus; Pharmacokinetics

Indexed keywords

CYCLODEXTRIN; NANOPARTICLE; POLYCATION; SMALL INTERFERING RNA;

EID: 84857438167     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200718109     Document Type: Article
Times cited : (310)

References (30)
  • 1
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D, Rossi JJ (2009) The promises and pitfalls of RNA-interference-based therapeutics. Nature 457:426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 3
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis ME, Chen ZG, Shin DM (2008) Nanoparticle therapeutics: An emerging treatment modality for cancer. Nat Rev Drug Discov 7:771-782.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 4
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • Davis ME, et al. (2010) Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464:1067-1070.
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1
  • 6
    • 61849103493 scopus 로고    scopus 로고
    • In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes
    • Malek A, et al. (2009) In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes. Toxicol Appl Pharmacol 236: 97-108.
    • (2009) Toxicol Appl Pharmacol , vol.236 , pp. 97-108
    • Malek, A.1
  • 7
    • 67651202350 scopus 로고    scopus 로고
    • Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
    • Merkel OM, et al. (2009) Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. J Control Release 138:148-159.
    • (2009) J Control Release , vol.138 , pp. 148-159
    • Merkel, O.M.1
  • 8
    • 77955240438 scopus 로고    scopus 로고
    • Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity
    • Merkel OM, et al. (2010) Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity. Mol Pharm 7:969-983.
    • (2010) Mol Pharm , vol.7 , pp. 969-983
    • Merkel, O.M.1
  • 9
    • 67649865399 scopus 로고    scopus 로고
    • The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice
    • Gao S, et al. (2009) The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Mol Ther 17:1225-1233.
    • (2009) Mol Ther , vol.17 , pp. 1225-1233
    • Gao, S.1
  • 12
    • 80053923147 scopus 로고    scopus 로고
    • Systemic delivery of siRNA via targeted nanoparticles in patients with cancer: Results from a first-in-class phase I clinical trial
    • Ribas A, et al. (2010) Systemic delivery of siRNA via targeted nanoparticles in patients with cancer: Results from a first-in-class phase I clinical trial. J Clin Oncol 28:3022.
    • (2010) J Clin Oncol , vol.28 , pp. 3022
    • Ribas, A.1
  • 13
    • 35148864458 scopus 로고    scopus 로고
    • Renal clearance of quantum dots
    • Choi HS, et al. (2007) Renal clearance of quantum dots. Nat Biotechnol 25:1165-1170.
    • (2007) Nat Biotechnol , vol.25 , pp. 1165-1170
    • Choi, H.S.1
  • 16
    • 0032727848 scopus 로고    scopus 로고
    • High-resolution ultrastructural comparison of renal glomerular and tubular basement membranes
    • Ogawa S, et al. (1999) High-resolution ultrastructural comparison of renal glomerular and tubular basement membranes. Am J Nephrol 19:686-693.
    • (1999) Am J Nephrol , vol.19 , pp. 686-693
    • Ogawa, S.1
  • 18
    • 34447306000 scopus 로고    scopus 로고
    • Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing
    • DOI 10.1002/bit.21285
    • Bartlett DW, Davis ME (2007) Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing. Biotechnol Bioeng 97:909-921. (Pubitemid 47051060)
    • (2007) Biotechnology and Bioengineering , vol.97 , Issue.4 , pp. 909-921
    • Bartlett, D.W.1    Davis, M.E.2
  • 19
    • 70350571814 scopus 로고    scopus 로고
    • Development of universal antidotes to control aptamer activity
    • Oney S, et al. (2009) Development of universal antidotes to control aptamer activity. Nat Med 15:1224-1228.
    • (2009) Nat Med , vol.15 , pp. 1224-1228
    • Oney, S.1
  • 20
    • 33845187169 scopus 로고    scopus 로고
    • Imidazole groups on a linear, cyclodextrin-containing polycation produce enhanced gene delivery via multiple processes
    • DOI 10.1016/j.jconrel.2006.06.018, PII S016836590600321X
    • Mishra S, Heidel JD, Webster P, Davis ME (2006) Imidazole groups on a linear, cyclodextrin- containing polycation produce enhanced gene delivery via multiple processes. J Control Release 116:179-191. (Pubitemid 44854276)
    • (2006) Journal of Controlled Release , vol.116 , Issue.2 SPEC. ISS. , pp. 179-191
    • Mishra, S.1    Heidel, J.D.2    Webster, P.3    Davis, M.E.4
  • 21
    • 0027404416 scopus 로고
    • Anionic charge concentration of rat kidney glomeruli and glomerular basement membrane
    • Comper WD, Lee AS, Tay M, Adal Y (1993) Anionic charge concentration of rat kidney glomeruli and glomerular basement membrane. Biochem J 289:647-652. (Pubitemid 23074944)
    • (1993) Biochemical Journal , vol.289 , Issue.3 , pp. 647-652
    • Comper, W.D.1    Lee, A.S.N.2    Tay, M.3    Adal, Y.4
  • 22
    • 0014949438 scopus 로고
    • Human glomerular basement membrane. Preparation and composition
    • Westberg NG, Michael AF (1970) Human glomerular basement membrane. Preparation and composition. Biochemistry 9:3837-3846.
    • (1970) Biochemistry , vol.9 , pp. 3837-3846
    • Westberg, N.G.1    Michael, A.F.2
  • 24
    • 68049136123 scopus 로고    scopus 로고
    • SiRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury
    • Molitoris BA, et al. (2009) siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J Am Soc Nephrol 20:1754-1764.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1754-1764
    • Molitoris, B.A.1
  • 25
    • 0018425671 scopus 로고
    • Anionic sites in the glomerular basement membrane. In vivo and vitro localization to the laminae rarae by cationic probes
    • Kanwar YS, Farquhar MG (1979) Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes. J Cell Biol 81: 137-153. (Pubitemid 9148443)
    • (1979) Journal of Cell Biology , vol.81 , Issue.1 , pp. 137-153
    • Kanwar, Y.S.1    Farquhar, M.G.2
  • 26
    • 41149086686 scopus 로고    scopus 로고
    • Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
    • DOI 10.1021/bc700388u
    • Burke RS, Pun SH (2008) Extracellular barriers to in Vivo PEI and PEGylated PEI polyplex- mediated gene delivery to the liver. Bioconjug Chem 19:693-704. (Pubitemid 351431402)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.3 , pp. 693-704
    • Burke, R.S.1    Pun, S.H.2
  • 27
    • 0034003313 scopus 로고    scopus 로고
    • Glomerular filtration is required for transfection of proximal tubular cells in the rat kidney following injection of DNA complexes into the renal artery
    • Foglieni C, et al. (2000) Glomerular filtration is required for transfection of proximal tubular cells in the rat kidney following injection of DNA complexes into the renal artery. Gene Ther 7:279-285. (Pubitemid 30119730)
    • (2000) Gene Therapy , vol.7 , Issue.4 , pp. 279-285
    • Foglieni, C.1    Bragonzi, A.2    Cortese, M.3    Cantu, L.4    Boletta, A.5    Chiossone, I.6    Soria, M.R.7    Monaco, L.8
  • 28
    • 0021783936 scopus 로고
    • Dose-dependent movement of cationic molecules across the glomerular wall
    • DOI 10.1002/ar.1092120302
    • Andrews PM, Bates SB (1985) Dose-dependent movement of cationic molecules across the glomerular wall. Anat Rec 212:223-231. (Pubitemid 15247826)
    • (1985) Anatomical Record , vol.212 , Issue.3 , pp. 223-231
    • Andrews, P.M.1    Bates, S.B.2
  • 29
    • 51449083381 scopus 로고    scopus 로고
    • MRI of the basement membrane using charged nanoparticles as contrast agents
    • Bennett KM, et al. (2008)) MRI of the basement membrane using charged nanoparticles as contrast agents. Magn Reson Med 60:564-574.
    • (2008) Magn Reson Med , vol.60 , pp. 564-574
    • Bennett, K.M.1
  • 30
    • 33947696667 scopus 로고    scopus 로고
    • Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles
    • DOI 10.1021/bc0603539
    • Bartlett DW, Davis ME (2007) Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. Bioconjug Chem 18:456-468. (Pubitemid 46493517)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.2 , pp. 456-468
    • Bartlett, D.W.1    Davis, M.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.