-
1
-
-
84892170718
-
Whats fueling the biotech engine-2012 to 2013
-
Aggarwal S. Whats fueling the biotech engine-2012 to 2013. Nat Biotechnol 2014; 32: 32-9
-
(2014)
Nat Biotechnol
, vol.32
, pp. 32-39
-
-
Aggarwal, S.1
-
3
-
-
84858665432
-
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile
-
Hrkach J, Von Hoff D, Ali MM, et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci Transl Med 2012; 4: 128ra39
-
(2012)
Sci Transl Med
, vol.4
, pp. 128ra39
-
-
Hrkach, J.1
Von Hoff, D.2
Ali, M.M.3
-
4
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
Davis ME, Zuckerman JE, Choi CHJ, et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010; 464: 1067-70
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.J.3
-
5
-
-
34250352899
-
Nanomedicine opportunities for cardiovascular disease with perfluorocarbon nanoparticles
-
Lanza GM, Winter PM, Caruthers SD, et al. Nanomedicine opportunities for cardiovascular disease with perfluorocarbon nanoparticles. Nanomed 2006; 1: 321-9
-
(2006)
Nanomed
, vol.1
, pp. 321-329
-
-
Lanza, G.M.1
Winter, P.M.2
Caruthers, S.D.3
-
6
-
-
84865580901
-
Nanomedicine for treatment of diabetes in an aging population: State-of-the-art and future developments
-
Krol S, Ellis-Behnke R, Marchetti P. Nanomedicine for treatment of diabetes in an aging population: state-of-the-art and future developments. Nanomedicine 2012; 8: S69-76
-
(2012)
Nanomedicine
, vol.8
, pp. 69-76
-
-
Krol, S.1
Ellis-Behnke, R.2
Marchetti, P.3
-
7
-
-
33750177969
-
Nanoscale analysis of protein and peptide absorption: Insulin absorption using complexation and pH-sensitive hydrogels as delivery vehicles
-
Peppas NA, Kavimandan NJ. Nanoscale analysis of protein and peptide absorption: insulin absorption using complexation and pH-sensitive hydrogels as delivery vehicles. Eur J Pharm Sci 2006; 29: 183-97
-
(2006)
Eur J Pharm Sci
, vol.29
, pp. 183-197
-
-
Peppas, N.A.1
Kavimandan, N.J.2
-
8
-
-
0031017851
-
Patient preferences for oral versus intravenous palliative chemotherapy
-
Liu G, Franssen E, Fitch MI, Warner E. Patient preferences for oral versus intravenous palliative chemotherapy. J Clin Oncol 1997; 15: 110-15
-
(1997)
J Clin Oncol
, vol.15
, pp. 110-115
-
-
Liu, G.1
Franssen, E.2
Fitch, M.I.3
Warner, E.4
-
9
-
-
0036159485
-
Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: A randomised crossover trial in advanced colorectal cancer
-
Borner MM, Schoffski P, de Wit R, et al. Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer. Eur J Cancer 2002; 38: 349-58
-
(2002)
Eur J Cancer
, vol.38
, pp. 349-358
-
-
Borner, M.M.1
Schoffski, P.2
De Wit, R.3
-
10
-
-
0035868768
-
Phase II comparator study of oral versus intravenous topotecan in patients with chemosensitive small-cell lung cancer
-
Von Pawel J, Gatzemeier U, Pujol JL, et al. Phase II comparator study of oral versus intravenous topotecan in patients with chemosensitive small-cell lung cancer. J Clin Oncol 2001; 19: 1743-9
-
(2001)
J Clin Oncol
, vol.19
, pp. 1743-1749
-
-
Von Pawel, J.1
Gatzemeier, U.2
Pujol, J.L.3
-
11
-
-
29644443435
-
Two-year clinical trial of oral alendronate versus intravenous pamidronate in children with osteogenesis imperfecta
-
DiMeglio LA, Peacock M. Two-year clinical trial of oral alendronate versus intravenous pamidronate in children with osteogenesis imperfecta. J Bone Miner Res 2006; 21: 132-40
-
(2006)
J Bone Miner Res
, vol.21
, pp. 132-140
-
-
DiMeglio, L.A.1
Peacock, M.2
-
12
-
-
33750179595
-
Patient preference for oral or intravenous chemotherapy: A randomised cross-over trial comparing capecitabine and Nordic fluorouracil/leucovorin in patients with colorectal cancer
-
Pfeiffer P, Mortensen JP, Bjerregaard B, et al. Patient preference for oral or intravenous chemotherapy: a randomised cross-over trial comparing capecitabine and Nordic fluorouracil/leucovorin in patients with colorectal cancer. Eur J Cancer 2006; 42: 2738-43
-
(2006)
Eur J Cancer
, vol.42
, pp. 2738-2743
-
-
Pfeiffer, P.1
Mortensen, J.P.2
Bjerregaard, B.3
-
13
-
-
38849106122
-
Effective oral chemotherapy for breast cancer: Pillars of strength
-
Findlay M, Von Minckwitz G, Wardley A. Effective oral chemotherapy for breast cancer: pillars of strength. Ann Oncol 2008; 19: 212-22
-
(2008)
Ann Oncol
, vol.19
, pp. 212-222
-
-
Findlay, M.1
Von Minckwitz, G.2
Wardley, A.3
-
14
-
-
4444346434
-
Savings in staff time as a result of switching from de Gramont to oral capecitabine for patients with advanced colorectal cancer [abstract 271]
-
James R, Blanco C, Farina C. Savings in staff time as a result of switching from de Gramont to oral capecitabine for patients with advanced colorectal cancer [abstract 271]. Eur J Cancer 2003; 1 (Suppl 5): S83
-
(2003)
Eur J Cancer
, vol.1
, pp. 83
-
-
James, R.1
Blanco, C.2
Farina, C.3
-
15
-
-
77951583120
-
Cost analysis of capecitabine vs 5-fluorouracil-based treatment for metastatic colorectal cancer patients
-
De Portu S, Mantovani LG, Ravaioli A, et al. Cost analysis of capecitabine vs 5-fluorouracil-based treatment for metastatic colorectal cancer patients. J Chemother 2010; 22: 125-8
-
(2010)
J Chemother
, vol.22
, pp. 125-128
-
-
De Portu, S.1
Mantovani, L.G.2
Ravaioli, A.3
-
16
-
-
2342624007
-
Cost-benefit analysis of capecitabine versus 5-fluorouracil/leucovorin in the treatment of colorectal cancer in the Netherlands
-
Jansman F, Postma M, van Hartskamp D, et al. Cost-benefit analysis of capecitabine versus 5-fluorouracil/leucovorin in the treatment of colorectal cancer in the Netherlands. Clin Ther 2004; 26: 579-89
-
(2004)
Clin Ther
, vol.26
, pp. 579-589
-
-
Jansman, F.1
Postma, M.2
Van Hartskamp, D.3
-
17
-
-
22244456090
-
Estimating patient time costs associated with colorectal cancer care
-
Yabroff K, Warren J, Knopf K, et al. Estimating patient time costs associated with colorectal cancer care. Med Care 2005; 43: 640-8
-
(2005)
Med Care
, vol.43
, pp. 640-648
-
-
Yabroff, K.1
Warren, J.2
Knopf, K.3
-
19
-
-
80054061227
-
A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery
-
Chen M-C, Sonaje K, Chen K-J, Sung H-W. A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery. Biomaterials 2011; 32: 9826-38
-
(2011)
Biomaterials
, vol.32
, pp. 9826-9838
-
-
Chen, M.-C.1
Sonaje, K.2
Chen, K.-J.3
Sung, H.-W.4
-
20
-
-
43549117511
-
The mucosal immune system at the gastrointestinal barrier
-
Schenk M, Mueller C. The mucosal immune system at the gastrointestinal barrier. Best Pract Res Clin Gastroenterol 2008; 22: 391-409
-
(2008)
Best Pract Res Clin Gastroenterol
, vol.22
, pp. 391-409
-
-
Schenk, M.1
Mueller, C.2
-
21
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald T, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005; 307: 1920-5
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.1
Monteleone, G.2
-
22
-
-
0029055473
-
Comparison of the gastrointestinal anatomy, physiology, and bio- chemistry of humans and commonly used laboratory-animals
-
Kararli T. Comparison of the gastrointestinal anatomy, physiology, and bio- chemistry of humans and commonly used laboratory-animals. Biopharm Drug Dispos 1995; 16: 351-80
-
(1995)
Biopharm Drug Dispos
, vol.16
, pp. 351-380
-
-
Kararli, T.1
-
23
-
-
0035498328
-
Peroral route: An opportunity for protein and peptide drug delivery
-
Sood A, Panchagnula R. Peroral route: an opportunity for protein and peptide drug delivery. Chem Rev 2001; 101: 3275-304
-
(2001)
Chem Rev
, vol.101
, pp. 3275-3304
-
-
Sood, A.1
Panchagnula, R.2
-
26
-
-
84859719708
-
Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
-
Ensign LM, Cone R, Hanes J. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. Adv Drug Deliv Rev 2012; 64: 557-70
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 557-570
-
-
Ensign, L.M.1
Cone, R.2
Hanes, J.3
-
29
-
-
60149089459
-
Barrier properties of mucus
-
Cone RA. Barrier properties of mucus. Adv Drug Deliv Rev 2009; 61: 75-85
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 75-85
-
-
Cone, R.A.1
-
30
-
-
19444373410
-
Theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: A novel mechanism for regulation of permeability
-
Banan A. theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. J Pharmacol Exp Ther 2005; 313: 962-82
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 962-982
-
-
Banan, A.1
-
31
-
-
0033851771
-
Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: Lessons from mutant animals and proteins
-
Mitic LL, Van Itallie CM, Anderson JM. Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 2000; 279: G250-4
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
, pp. 250-254
-
-
Mitic, L.L.1
Van Itallie, C.M.2
Anderson, J.M.3
-
32
-
-
0344465840
-
Potential role of MCP-1 in endothelial cell tight junction 'opening: Signaling via Rho and Rho kinase
-
Stamatovic SM, Keep R, Kunkel S, Andjelkovic A. Potential role of MCP-1 in endothelial cell tight junction 'opening: signaling via Rho and Rho kinase. J Cell Sci 2003; 116: 4615-28
-
(2003)
J Cell Sci
, vol.116
, pp. 4615-4628
-
-
Stamatovic, S.M.1
Keep, R.2
Kunkel, S.3
Andjelkovic, A.4
-
34
-
-
0031859489
-
Oral chemotherapy: Rationale and future directions
-
DeMario MD, Ratain MJ. Oral chemotherapy: rationale and future directions. J Clin Oncol 1998; 16: 2557-67
-
(1998)
J Clin Oncol
, vol.16
, pp. 2557-2567
-
-
DeMario, M.D.1
Ratain, M.J.2
-
35
-
-
33646492929
-
Tight junction modulation and its relationship to drug delivery
-
Salama N, Eddington N, Fasano A. Tight junction modulation and its relationship to drug delivery. Adv Drug Deliv Rev 2006; 58: 15-28
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 15-28
-
-
Salama, N.1
Eddington, N.2
Fasano, A.3
-
36
-
-
29144461657
-
Polymeric nanoparticles for oral delivery of drugs and vaccines: A critical evaluation of in vivo studies
-
Galindo-Rodriguez S, Allemann E, Fessi H, Doelker E. Polymeric nanoparticles for oral delivery of drugs and vaccines: a critical evaluation of in vivo studies. Crit Rev Ther Drug Carrier Syst 2005; 22: 419-64
-
(2005)
Crit Rev Ther Drug Carrier Syst
, vol.22
, pp. 419-464
-
-
Galindo-Rodriguez, S.1
Allemann, E.2
Fessi, H.3
Doelker, E.4
-
37
-
-
84939644244
-
-
1st edition. Taylor and Francis Group, LLC; Boca Raton, FL
-
Moore T, Graham E, Mattix B, Alexis F. Biomaterials science: an integrated clinical and engineering approach. 1st edition. Taylor and Francis Group, LLC; Boca Raton, FL: 2012
-
(2012)
Biomaterials Science: An Integrated Clinical and Engineering Approach
-
-
Moore, T.1
Graham, E.2
Mattix, B.3
Alexis, F.4
-
39
-
-
0028283741
-
Calcitonin and insulin in isobutylcyanoacrylate nanocap- sules - Protection against proteases and effect on intestinal-absorption in rats
-
Lowe PJ, Temple CS. Calcitonin and insulin in isobutylcyanoacrylate nanocap- sules-protection against proteases and effect on intestinal-absorption in rats. J Pharm Pharmacol 1994; 46: 547-52
-
(1994)
J Pharm Pharmacol
, vol.46
, pp. 547-552
-
-
Lowe, P.J.1
Temple, C.S.2
-
40
-
-
0031446134
-
Poly (alkyl cyanoacrylate) nanospheres for oral administration of insulin
-
Damge C, Vranckx H, Balschmidt P, Couvreur P. Poly (alkyl cyanoacrylate) nanospheres for oral administration of insulin. J Pharm Sci 1997; 86: 1403-9
-
(1997)
J Pharm Sci
, vol.86
, pp. 1403-1409
-
-
Damge, C.1
Vranckx, H.2
Balschmidt, P.3
Couvreur, P.4
-
41
-
-
51049092308
-
Factors affecting the clearance and biodistribution of polymeric nanoparticles
-
Alexis F, Pridgen E, Molnar LK, Farokhzad OC. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 2008; 5: 505-15
-
(2008)
Mol Pharm
, vol.5
, pp. 505-515
-
-
Alexis, F.1
Pridgen, E.2
Molnar, L.K.3
Farokhzad, O.C.4
-
42
-
-
84891362991
-
Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy
-
Valencia PM, Pridgen EM, Rhee M, et al. Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy. ACS Nano 2013; 7: 10671-80
-
(2013)
ACS Nano
, vol.7
, pp. 10671-10680
-
-
Valencia, P.M.1
Pridgen, E.M.2
Rhee, M.3
-
43
-
-
84863666971
-
Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy
-
Yu MK, Park J, Jon S. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. Theranostics 2012; 2: 3-44
-
(2012)
Theranostics
, vol.2
, pp. 3-44
-
-
Yu, M.K.1
Park, J.2
Jon, S.3
-
45
-
-
73349140554
-
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
-
Tang BC, Dawson M, Lai SK, et al. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci USA 2009; 106: 19268-73
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19268-19273
-
-
Tang, B.C.1
Dawson, M.2
Lai, S.K.3
-
46
-
-
26644454810
-
The basics and underlying mechanisms of mucoadhesion
-
Smart J. The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev 2005; 57: 1556-68
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 1556-1568
-
-
Smart, J.1
-
47
-
-
60149111908
-
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
-
Lai SK, Wang Y-Y, Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev 2009; 61: 158-71
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 158-171
-
-
Lai, S.K.1
Wang, Y.-Y.2
Hanes, J.3
-
48
-
-
79953242692
-
Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa
-
Dünnhaupt S, Barthelmes J, Hombach J, et al. Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa. Int J Pharm 2011; 408: 191-9
-
(2011)
Int J Pharm
, vol.408
, pp. 191-199
-
-
Dünnhaupt, S.1
Barthelmes, J.2
Hombach, J.3
-
49
-
-
78651228118
-
A mucoadhesive nanoparticulate system for the simultaneous delivery of macromolecules and permeation enhancers to the intestinal mucosa
-
Makhlof A, Werle M, Tozuka Y, Takeuchi H. A mucoadhesive nanoparticulate system for the simultaneous delivery of macromolecules and permeation enhancers to the intestinal mucosa. J Control Release 2011; 149: 81-8
-
(2011)
J Control Release
, vol.149
, pp. 81-88
-
-
Makhlof, A.1
Werle, M.2
Tozuka, Y.3
Takeuchi, H.4
-
50
-
-
84878862620
-
Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules
-
Chen M-C, Mi F-L, Liao Z-X, et al. Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules. Adv Drug Deliv Rev 2013; 65: 865-79
-
(2013)
Adv Drug Deliv Rev
, vol.65
, pp. 865-879
-
-
Chen, M.-C.1
Mi, F.-L.2
Liao, Z.-X.3
-
51
-
-
36549049905
-
Oral delivery of insulin loaded poly(fumaric-co-sebacic) anhydride microspheres
-
Furtado S, Abramson D, Burrill R, et al. Oral delivery of insulin loaded poly(fumaric-co-sebacic) anhydride microspheres. Int J Pharm 2008; 347: 149-55
-
(2008)
Int J Pharm
, vol.347
, pp. 149-155
-
-
Furtado, S.1
Abramson, D.2
Burrill, R.3
-
53
-
-
26644447977
-
Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems
-
Takeuchi H, Thongborisute J, Matsui Y, et al. Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems. Adv Drug Deliv Rev 2005; 57: 1583-94
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 1583-1594
-
-
Takeuchi, H.1
Thongborisute, J.2
Matsui, Y.3
-
54
-
-
0034000923
-
Molecular aspects of muco-and bioadhesion:: Tethered structures and site-specific surfaces
-
Huang Y, Leobandung W, Foss A, Peppas NA. Molecular aspects of muco-and bioadhesion:: tethered structures and site-specific surfaces. J Control Release 2000; 65: 63-71
-
(2000)
J Control Release
, vol.65
, pp. 63-71
-
-
Huang, Y.1
Leobandung, W.2
Foss, A.3
Peppas, N.A.4
-
55
-
-
0344359721
-
Chitosan for enhanced intestinal permeability: Prospects for derivatives soluble in neutral and basic environments
-
Kotze AF, Luessen HL, De Boer AG, et al. Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments. Eur J Pharm Sci 1999; 7: 145-51
-
(1999)
Eur J Pharm Sci
, vol.7
, pp. 145-151
-
-
Kotze, A.F.1
Luessen, H.L.2
De Boer, A.G.3
-
56
-
-
77950916224
-
Insulin-loaded nanoparticles based on N-trimethyl chitosan: In vitro (Caco-2 Model) and ex vivo (excised rat jejunum, duodenum, and ileum) evaluation of penetration enhancement properties
-
Sandri G, Bonferoni MC, Rossi S, et al. Insulin-loaded nanoparticles based on N-trimethyl chitosan: in vitro (Caco-2 Model) and ex vivo (excised rat jejunum, duodenum, and ileum) evaluation of penetration enhancement properties. AAPS PharmSciTech 2010; 11: 362-71
-
(2010)
AAPS PharmSciTech
, vol.11
, pp. 362-371
-
-
Sandri, G.1
Bonferoni, M.C.2
Rossi, S.3
-
57
-
-
1542509567
-
Oral insulin delivery: The potential of thiolated chitosan-insulin tablets on non-diabetic rats
-
Krauland AH, Guggi D, Bernkop-Schnürch A. Oral insulin delivery: the potential of thiolated chitosan-insulin tablets on non-diabetic rats. J Control Release 2004; 95: 547-55
-
(2004)
J Control Release
, vol.95
, pp. 547-555
-
-
Krauland, A.H.1
Guggi, D.2
Bernkop-Schnürch, A.3
-
58
-
-
33846799473
-
Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles
-
Bravo-Osuna I, Vauthier C, Farabollini A, et al. Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles. Biomaterials 2007; 28: 2233-43
-
(2007)
Biomaterials
, vol.28
, pp. 2233-2243
-
-
Bravo-Osuna, I.1
Vauthier, C.2
Farabollini, A.3
-
59
-
-
60849130683
-
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
-
Sonaje K, Lin Y-H, Juang J-H, et al. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials 2009; 30: 2329-39
-
(2009)
Biomaterials
, vol.30
, pp. 2329-2339
-
-
Sonaje, K.1
Lin, Y.-H.2
Juang, J.-H.3
-
60
-
-
0029102179
-
Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: Uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers
-
Adson A, Burton PS, Raub TJ, et al. Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers. J Pharm Sci 1995; 84: 1197-204
-
(1995)
J Pharm Sci
, vol.84
, pp. 1197-1204
-
-
Adson, A.1
Burton, P.S.2
Raub, T.J.3
-
61
-
-
84860726458
-
Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: Microscopic, ultrastructural, and computed-tomographic observations
-
Sonaje K, Chuang E-Y, Lin K-J, et al. Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: microscopic, ultrastructural, and computed-tomographic observations. Mol Pharm 2012; 9: 1271-9
-
(2012)
Mol Pharm
, vol.9
, pp. 1271-1279
-
-
Sonaje, K.1
Chuang, E.-Y.2
Lin, K.-J.3
-
62
-
-
77954385916
-
Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: Oral delivery using pH-Responsive nanoparticles vs subcutaneous injection
-
Sonaje K, Lin K-J, Wey S-P, et al. Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-Responsive nanoparticles vs. subcutaneous injection. Biomaterials 2010; 31: 6849-58
-
(2010)
Biomaterials
, vol.31
, pp. 6849-6858
-
-
Sonaje, K.1
Lin, K.-J.2
Wey, S.-P.3
-
63
-
-
79959876473
-
Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening
-
Yeh T-H, Hsu L-W, Tseng MT, et al. Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening. Biomaterials 2011; 32: 6164-73
-
(2011)
Biomaterials
, vol.32
, pp. 6164-6173
-
-
Yeh, T.-H.1
Hsu, L.-W.2
Tseng, M.T.3
-
64
-
-
80052966755
-
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins
-
Sonaje K, Lin K-J, Tseng MT, et al. Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins. Biomaterials 2011; 32: 8712-21
-
(2011)
Biomaterials
, vol.32
, pp. 8712-8721
-
-
Sonaje, K.1
Lin, K.-J.2
Tseng, M.T.3
-
65
-
-
17844406157
-
Intestinal absorption enhancement via the paracellular route by fatty acids, chitosans and others: A target for drug delivery
-
Cano-Cebrian MJ, Zornoza T, Granero L, Polache A. Intestinal absorption enhancement via the paracellular route by fatty acids, chitosans and others: a target for drug delivery. Curr Drug Deliv 2005; 2: 9-22
-
(2005)
Curr Drug Deliv
, vol.2
, pp. 9-22
-
-
Cano-Cebrian, M.J.1
Zornoza, T.2
Granero, L.3
Polache, A.4
-
67
-
-
11144358593
-
Intestinal villous M cells: An antigen entry site in the mucosal epithelium
-
Jang MH, Kweon M-N, Iwatani K, et al. Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc Natl Acad Sci USA 2004; 101: 6110-15
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6110-6115
-
-
Jang, M.H.1
Kweon, M.-N.2
Iwatani, K.3
-
68
-
-
0025069886
-
Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyers patches
-
Eldridge JH, Hammond CJ, Meulbroek JA, et al. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyers patches. J Control Release 1990; 11: 205-14
-
(1990)
J Control Release
, vol.11
, pp. 205-214
-
-
Eldridge, J.H.1
Hammond, C.J.2
Meulbroek, J.A.3
-
69
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
-
Des Rieux A, Fievez V, Garinot M, et al. Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J Control Release 2006; 116: 1-27
-
(2006)
J Control Release
, vol.116
, pp. 1-27
-
-
Des Rieux, A.1
Fievez, V.2
Garinot, M.3
-
70
-
-
33947265152
-
An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells
-
Des Rieux A, Fievez V, Théate I, et al. An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells. Eur J Pharm Sci 2007; 30: 380-91
-
(2007)
Eur J Pharm Sci
, vol.30
, pp. 380-391
-
-
Des Rieux, A.1
Fievez, V.2
Théate, I.3
-
71
-
-
77952491719
-
Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery
-
Roger E, Lagarce F, Garcion E, Benoit J-P. Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery. Nanomed 2010; 5: 287-306
-
(2010)
Nanomed
, vol.5
, pp. 287-306
-
-
Roger, E.1
Lagarce, F.2
Garcion, E.3
Benoit, J.-P.4
-
74
-
-
0026950068
-
Confocal analysis of fluorescent bead uptake by mouse Peyers patch follicle-associated M cells
-
Porta C, James PS, Phillips AD, et al. Confocal analysis of fluorescent bead uptake by mouse Peyers patch follicle-associated M cells. Exp Physiol 1992; 77: 929-32
-
(1992)
Exp Physiol
, vol.77
, pp. 929-932
-
-
Porta, C.1
James, P.S.2
Phillips, A.D.3
-
75
-
-
0034822710
-
Oral vaccination in man using antigens in particles: Current status
-
Brayden DJ. Oral vaccination in man using antigens in particles: current status. Eur J Pharm Sci 2001; 14: 183-9
-
(2001)
Eur J Pharm Sci
, vol.14
, pp. 183-189
-
-
Brayden, D.J.1
-
76
-
-
84864606285
-
Recent advances in nanocarrier-based mucosal delivery of biomolecules
-
Kammona O, Kiparissides C. Recent advances in nanocarrier-based mucosal delivery of biomolecules. J Control Release 2012; 161: 781-94
-
(2012)
J Control Release
, vol.161
, pp. 781-794
-
-
Kammona, O.1
Kiparissides, C.2
-
77
-
-
84898470940
-
A population of Langerin-positive dendritic cells in murine Peyers patches involved in sampling β-glucan microparticles
-
De Jesus M, Ostroff GR, Levitz SM, et al. A population of Langerin-positive dendritic cells in murine Peyers patches involved in sampling β-glucan microparticles. PLoS One 2014; 9: e91002
-
(2014)
PLoS One
, vol.9
, pp. 91002
-
-
De Jesus, M.1
Ostroff, G.R.2
Levitz, S.M.3
-
78
-
-
36248965689
-
Current challenges in non-invasive insulin delivery systems: A comparative review
-
Khafagy E-S, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Deliv Rev 2007; 59: 1521-46
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1521-1546
-
-
Khafagy, E.-S.1
Morishita, M.2
Onuki, Y.3
Takayama, K.4
-
79
-
-
68349160864
-
Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination
-
Fievez V, Plapied L, des Rieux A, et al. Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination. Eur J Pharm Biopharm 2009; 73: 16-24
-
(2009)
Eur J Pharm Biopharm
, vol.73
, pp. 16-24
-
-
Fievez, V.1
Plapied, L.2
Des Rieux, A.3
-
80
-
-
0032167625
-
Studying M cells and their role in infection
-
Jepson MA, Clark MA. Studying M cells and their role in infection. Trends Microbiol 1998; 6: 359-65
-
(1998)
Trends Microbiol
, vol.6
, pp. 359-365
-
-
Jepson, M.A.1
Clark, M.A.2
-
82
-
-
0025908008
-
Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyers patch M cells
-
Pappo J, Ermak TH, Steger HJ. Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyers patch M cells. Immunology 1991; 73: 277
-
(1991)
Immunology
, vol.73
, pp. 277
-
-
Pappo, J.1
Ermak, T.H.2
Steger, H.J.3
-
85
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
-
Desai MP, Labhasetwar V, Amidon GL, Levy RJ. Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm Res 1996; 13: 1838-45
-
(1996)
Pharm Res
, vol.13
, pp. 1838-1845
-
-
Desai, M.P.1
Labhasetwar, V.2
Amidon, G.L.3
Levy, R.J.4
-
86
-
-
0031469673
-
The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent
-
Desai MP, Lab V, Walter E, et al. The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm Res 1997; 14: 1568-73
-
(1997)
Pharm Res
, vol.14
, pp. 1568-1573
-
-
Desai, M.P.1
Lab, V.2
Walter, E.3
-
87
-
-
0037177459
-
Lectin-mediated drug delivery: Binding and uptake of BSA-WGA conjugates using the Caco-2 model
-
Gabor F, Schwarzbauer A, Wirth M. Lectin-mediated drug delivery: binding and uptake of BSA-WGA conjugates using the Caco-2 model. Int J Pharm 2002; 237: 227-39
-
(2002)
Int J Pharm
, vol.237
, pp. 227-239
-
-
Gabor, F.1
Schwarzbauer, A.2
Wirth, M.3
-
88
-
-
0030774645
-
Lectin-mediated bioadhesion: Proteolytic stability and binding-characteristics of wheat germ agglutinin and Solanum tuberosum lectin on Caco-2, HT-29 and human colonocytes
-
Gabor F, Wirth M, Jurkovich B, et al. Lectin-mediated bioadhesion: proteolytic stability and binding-characteristics of wheat germ agglutinin and Solanum tuberosum lectin on Caco-2, HT-29 and human colonocytes. J Control Release 1997; 49: 27-37
-
(1997)
J Control Release
, vol.49
, pp. 27-37
-
-
Gabor, F.1
Wirth, M.2
Jurkovich, B.3
-
89
-
-
0022427984
-
Tomato lectin resists digestion in the mammalian alimentary canal and binds to intestinal villi without deleterious effects
-
Kilpatrick DC, Pusztai A, Grant G, et al. Tomato lectin resists digestion in the mammalian alimentary canal and binds to intestinal villi without deleterious effects. FEBS Lett 1985; 185: 299-305
-
(1985)
FEBS Lett
, vol.185
, pp. 299-305
-
-
Kilpatrick, D.C.1
Pusztai, A.2
Grant, G.3
-
90
-
-
0030952669
-
Enhanced oral uptake of tomato lectin- conjugated nanoparticles in the rat
-
Hussain N, Jani PU, Florence AT. Enhanced oral uptake of tomato lectin- conjugated nanoparticles in the rat. Pharm Res 1997; 14: 613-18
-
(1997)
Pharm Res
, vol.14
, pp. 613-618
-
-
Hussain, N.1
Jani, P.U.2
Florence, A.T.3
-
91
-
-
6344256207
-
Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by caco-2 monolayers
-
Weissenboeck A, Bogner E, Wirth M, Gabor F. Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by caco-2 monolayers. Pharm Res 2004; 21: 1917-23
-
(2004)
Pharm Res
, vol.21
, pp. 1917-1923
-
-
Weissenboeck, A.1
Bogner, E.2
Wirth, M.3
Gabor, F.4
-
92
-
-
0242584996
-
Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence
-
Lochner N, Pittner F, Wirth M, Gabor F. Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence. Pharm Res 2003; 20: 833-9
-
(2003)
Pharm Res
, vol.20
, pp. 833-839
-
-
Lochner, N.1
Pittner, F.2
Wirth, M.3
Gabor, F.4
-
93
-
-
0034734982
-
Lectin-mediated mucosal delivery of drugs and microparticles
-
Clark M, Hirst BH, Jepson MA. Lectin-mediated mucosal delivery of drugs and microparticles. Adv Drug Deliv Rev 2000; 43: 207-23
-
(2000)
Adv Drug Deliv Rev
, vol.43
, pp. 207-223
-
-
Clark, M.1
Hirst, B.H.2
Jepson, M.A.3
-
94
-
-
1142309558
-
Lectin-mediated drug targeting: History and applications
-
Bies C, Lehr C-M, Woodley JF. Lectin-mediated drug targeting: history and applications. Adv Drug Deliv Rev 2004; 56: 425-35
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 425-435
-
-
Bies, C.1
Lehr, C.-M.2
Woodley, J.F.3
-
95
-
-
84863325067
-
Folic acid functionalized nanoparticles for enhanced oral drug delivery
-
Roger E, Kalscheuer S, Kirtane A, et al. Folic acid functionalized nanoparticles for enhanced oral drug delivery. Mol Pharm 2012; 9: 2103-10
-
(2012)
Mol Pharm
, vol.9
, pp. 2103-2110
-
-
Roger, E.1
Kalscheuer, S.2
Kirtane, A.3
-
96
-
-
59049088260
-
Traveling the vitamin B12 pathway: Oral delivery of protein and peptide drugs
-
Petrus AK, Fairchild TJ, Doyle RP. Traveling the vitamin B12 pathway: oral delivery of protein and peptide drugs. Angew Chem Int Ed 2009; 48: 1022-8
-
(2009)
Angew Chem Int Ed
, vol.48
, pp. 1022-1028
-
-
Petrus, A.K.1
Fairchild, T.J.2
Doyle, R.P.3
-
97
-
-
84885433680
-
Nanoparticle transport in epithelial cells: Pathway switching through bioconjugation
-
Fowler R, Vllasaliu D, Trillo FF, et al. Nanoparticle transport in epithelial cells: pathway switching through bioconjugation. Small 2013; 9: 3282-94
-
(2013)
Small
, vol.9
, pp. 3282-3294
-
-
Fowler, R.1
Vllasaliu, D.2
Trillo, F.F.3
-
98
-
-
34447577190
-
Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
-
Chalasani KB, Russell-Jones GJ, et al. Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles. J Control Release 2007; 122: 141-50
-
(2007)
J Control Release
, vol.122
, pp. 141-150
-
-
Chalasani, K.B.1
Russell-Jones, G.J.2
-
99
-
-
33846940490
-
A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin
-
Chalasani KB, Russell-Jones GJ, Yandrapu SK, et al. A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin. J Control Release 2007; 117: 421-9
-
(2007)
J Control Release
, vol.117
, pp. 421-429
-
-
Chalasani, K.B.1
Russell-Jones, G.J.2
Yandrapu, S.K.3
-
100
-
-
2942516894
-
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells
-
Yoshida M, Claypool SM, Wagner JS, et al. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity 2004; 20: 769-83
-
(2004)
Immunity
, vol.20
, pp. 769-783
-
-
Yoshida, M.1
Claypool, S.M.2
Wagner, J.S.3
-
101
-
-
1642546286
-
Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor
-
Claypool SM, Dickinson BL, Wagner JS, et al. Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor. Mol Biol Cell 2004; 15: 1746-59
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1746-1759
-
-
Claypool, S.M.1
Dickinson, B.L.2
Wagner, J.S.3
-
102
-
-
0030880901
-
Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells
-
Israel EJ, Taylor S, Wu Z, et al. Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells. Immunology 1997; 92: 69-74
-
(1997)
Immunology
, vol.92
, pp. 69-74
-
-
Israel, E.J.1
Taylor, S.2
Wu, Z.3
-
103
-
-
0027249327
-
The class i major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release
-
Raghavan M, Gastinel LN, Bjorkman PJ. The class I major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release. Biochemistry (Mosc) 1993; 32: 8654-60
-
(1993)
Biochemistry (Mosc)
, vol.32
, pp. 8654-8660
-
-
Raghavan, M.1
Gastinel, L.N.2
Bjorkman, P.J.3
-
104
-
-
84869005515
-
Gastrointestinal pH profile in subjects with irritable bowel syndrome
-
Lalezari D. Gastrointestinal pH profile in subjects with irritable bowel syndrome. Ann Gastroenterol 2012; 25: 333
-
(2012)
Ann Gastroenterol
, vol.25
, pp. 333
-
-
Lalezari, D.1
-
106
-
-
84890028543
-
Transepithelial transport of Fc-targeted nanoparticles by the neonatal Fc receptor for oral delivery
-
Pridgen EM, Alexis F, Kuo TT, et al. Transepithelial transport of Fc-targeted nanoparticles by the neonatal Fc receptor for oral delivery. Sci Transl Med 2013; 5: 213ra167
-
(2013)
Sci Transl Med
, vol.5
, pp. 213ra167
-
-
Pridgen, E.M.1
Alexis, F.2
Kuo, T.T.3
-
107
-
-
18144428664
-
The use of U-500 in patients with extreme insulin resistance
-
Cochran E, Musso C, Gorden P. The use of U-500 in patients with extreme insulin resistance. Diabetes Care 2005; 28: 1240-4
-
(2005)
Diabetes Care
, vol.28
, pp. 1240-1244
-
-
Cochran, E.1
Musso, C.2
Gorden, P.3
-
108
-
-
67549142429
-
Coadministration of Ritonavir Strongly Enhances the Apparent Oral Bioavailability of Docetaxel in Patients with Solid Tumors
-
Oostendorp RL, Huitema A, Rosing H, et al. Coadministration of Ritonavir Strongly Enhances the Apparent Oral Bioavailability of Docetaxel in Patients with Solid Tumors. Clin Cancer Res 2009; 15: 4228-33
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4228-4233
-
-
Oostendorp, R.L.1
Huitema, A.2
Rosing, H.3
-
109
-
-
84886443643
-
Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption
-
Attili-Qadri S, Karra N, Nemirovski A, et al. Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption. Proc Natl Acad Sci USA 2013; 110: 17498-503
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 17498-17503
-
-
Attili-Qadri, S.1
Karra, N.2
Nemirovski, A.3
-
110
-
-
57749108568
-
In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities
-
Bisht S, Feldmann G, Koorstra J-BM, et al. In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities. Mol Cancer Ther 2008; 7: 3878-88
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3878-3888
-
-
Bisht, S.1
Feldmann, G.2
Koorstra, J.-B.3
-
111
-
-
4344640503
-
The physiological rationale for oral insulin administration
-
Arbit E. The physiological rationale for oral insulin administration. Diabetes Technol Ther 2004; 6: 510-17
-
(2004)
Diabetes Technol Ther
, vol.6
, pp. 510-517
-
-
Arbit, E.1
-
112
-
-
0035656524
-
Insulin therapy during peritoneal dialysis: Pros and cons of various forms of administration
-
Quellhorst E. Insulin therapy during peritoneal dialysis: pros and cons of various forms of administration. J Am Soc Nephrol 2002; 13: S92-6
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 92-96
-
-
Quellhorst, E.1
-
113
-
-
0023411755
-
Human insulin. A review of its biological activity, pharmacokinetics and therapeutic use
-
Brogden RN, Heel RC. Human insulin. A review of its biological activity, pharmacokinetics and therapeutic use. Drugs 1987; 34: 350-71
-
(1987)
Drugs
, vol.34
, pp. 350-371
-
-
Brogden, R.N.1
Heel, R.C.2
-
114
-
-
79953085303
-
Drug adherence and multidisciplinary care in patients with multiple sclerosis: Protocol of a prospective, web-based, patient-centred, nation-wide, Dutch cohort study in glatiramer acetate treated patients (CAIR study)
-
Jongen PJ, Hengstman G, Hupperts R, et al. Drug adherence and multidisciplinary care in patients with multiple sclerosis: protocol of a prospective, web-based, patient-centred, nation-wide, Dutch cohort study in glatiramer acetate treated patients (CAIR study). BMC Neurol 2011; 11: 40
-
(2011)
BMC Neurol
, vol.11
, pp. 40
-
-
Jongen, P.J.1
Hengstman, G.2
Hupperts, R.3
-
115
-
-
84886719997
-
A novel pH-sensitive interferon-β (INF-β) oral delivery system for application in multiple sclerosis
-
Kondiah PPD, Tomar LK, Tyagi C, et al. A novel pH-sensitive interferon-β (INF-β) oral delivery system for application in multiple sclerosis. Int J Pharm 2013; 456: 459-72
-
(2013)
Int J Pharm
, vol.456
, pp. 459-472
-
-
Kondiah, P.P.D.1
Tomar, L.K.2
Tyagi, C.3
-
116
-
-
0348026751
-
In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix
-
Guggi D, Kast CE, Bernkop-Schnürch A. In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix. Pharm Res 2003; 20: 1989-94
-
(2003)
Pharm Res
, vol.20
, pp. 1989-1994
-
-
Guggi, D.1
Kast, C.E.2
Bernkop-Schnürch, A.3
-
117
-
-
84856923602
-
Salmon calcitonin-loaded Eudragit® and Eudragit®-PLGA nanoparticles: In vitro and in vivo evaluation
-
Cetin M, Aktas MS, Vural I, Ozturk M. Salmon calcitonin-loaded Eudragit® and Eudragit®-PLGA nanoparticles: in vitro and in vivo evaluation. J Microencapsul 2012; 29: 156-66
-
(2012)
J Microencapsul
, vol.29
, pp. 156-166
-
-
Cetin, M.1
Aktas, M.S.2
Vural, I.3
Ozturk, M.4
-
118
-
-
33747795904
-
Disease, destination, dose and delivery aspects of ciclosporin: The state of the art
-
Italia JL, Bhardwaj V, Ravi Kumar MNV. Disease, destination, dose and delivery aspects of ciclosporin: the state of the art. Drug Discov Today 2006; 11: 846-54
-
(2006)
Drug Discov Today
, vol.11
, pp. 846-854
-
-
Italia, J.L.1
Bhardwaj, V.2
Ravi Kumar, M.N.V.3
-
119
-
-
34249087392
-
PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral®
-
Italia JL, Bhatt DK, Bhardwaj V, et al. PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral®. J Control Release 2007; 119: 197-206
-
(2007)
J Control Release
, vol.119
, pp. 197-206
-
-
Italia, J.L.1
Bhatt, D.K.2
Bhardwaj, V.3
-
120
-
-
25644442467
-
Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
-
Lamprecht A. Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J Pharmacol Exp Ther 2005; 315: 196-202
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 196-202
-
-
Lamprecht, A.1
-
121
-
-
0035006742
-
An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis
-
Nakase H, Okazaki K, Tabata Y, et al. An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis. J Pharmacol Exp Ther 2001; 297: 1122-8
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1122-1128
-
-
Nakase, H.1
Okazaki, K.2
Tabata, Y.3
-
122
-
-
84859065561
-
Polymeric nanoparticles for the selective therapy of inflammatory bowel disease
-
Wachsmann P, Lamprecht A. Polymeric nanoparticles for the selective therapy of inflammatory bowel disease. Methods Enzymol 2012; 508: 377-97
-
(2012)
Methods Enzymol
, vol.508
, pp. 377-397
-
-
Wachsmann, P.1
Lamprecht, A.2
-
123
-
-
0034872426
-
Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa
-
Lamprecht A, Schäfer U, Lehr C-M. Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 2001; 18: 788-93
-
(2001)
Pharm Res
, vol.18
, pp. 788-793
-
-
Lamprecht, A.1
Schäfer, U.2
Lehr, C.-M.3
-
124
-
-
0034756945
-
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
-
Lamprecht A, Ubrich N, Yamamoto H, et al. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther 2001; 299: 775-81
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 775-781
-
-
Lamprecht, A.1
Ubrich, N.2
Yamamoto, H.3
-
125
-
-
35548970264
-
5-amino salicylic acid bound nanoparticles for the therapy of inflammatory bowel disease
-
Pertuit D, Moulari B, Betz T, et al. 5-amino salicylic acid bound nanoparticles for the therapy of inflammatory bowel disease. J Control Release 2007; 123: 211-18
-
(2007)
J Control Release
, vol.123
, pp. 211-218
-
-
Pertuit, D.1
Moulari, B.2
Betz, T.3
-
126
-
-
84901307815
-
Fab-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis
-
Laroui H, Viennois E, Xiao B, et al. Fab-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis. J Control Release 2014; 186: 41-53
-
(2014)
J Control Release
, vol.186
, pp. 41-53
-
-
Laroui, H.1
Viennois, E.2
Xiao, B.3
-
127
-
-
84903199454
-
Lectin-decorated nanoparticles enhance binding to the inflamed tissue in experimental colitis
-
Moulari B, Béduneau A, Pellequer Y, Lamprecht A. Lectin-decorated nanoparticles enhance binding to the inflamed tissue in experimental colitis. J Control Release 2014; 188: 9-17
-
(2014)
J Control Release
, vol.188
, pp. 9-17
-
-
Moulari, B.1
Béduneau, A.2
Pellequer, Y.3
Lamprecht, A.4
-
128
-
-
77958494386
-
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines
-
Wilson DS, Dalmasso G, Wang L, et al. Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines. Nat Mater 2010; 9: 923-8
-
(2010)
Nat Mater
, vol.9
, pp. 923-928
-
-
Wilson, D.S.1
Dalmasso, G.2
Wang, L.3
-
129
-
-
0032958073
-
Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
-
Roy K, Mao H-Q, Huang S-K, Leong KW. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med 1999; 5: 387-91
-
(1999)
Nat Med
, vol.5
, pp. 387-391
-
-
Roy, K.1
Mao, H.-Q.2
Huang, S.-K.3
Leong, K.W.4
-
130
-
-
0038513487
-
Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, der p 1 for oral vaccination in mice
-
Chew JL, Wolfowicz CB, Mao H-Q, et al. Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. Vaccine 2003; 21: 2720-9
-
(2003)
Vaccine
, vol.21
, pp. 2720-2729
-
-
Chew, J.L.1
Wolfowicz, C.B.2
Mao, H.-Q.3
-
131
-
-
65549110410
-
Induction of Th1-type immune response by chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen der p 2 for oral vaccination in mice
-
Li GP, Liu ZG, Liao B, Zhong NS. Induction of Th1-type immune response by chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen Der p 2 for oral vaccination in mice. Cell Mol Immunol 2009; 6: 45-50
-
(2009)
Cell Mol Immunol
, vol.6
, pp. 45-50
-
-
Li, G.P.1
Liu, Z.G.2
Liao, B.3
Zhong, N.S.4
-
132
-
-
0024780119
-
Vaccine-containing biodegradable microspheres specifically enter the gut-associated lymphoid tissue following oral administration and induce a disseminated mucosal immune response
-
Eldridge JH, Meulbroek JA, Staas JK, et al. Vaccine-containing biodegradable microspheres specifically enter the gut-associated lymphoid tissue following oral administration and induce a disseminated mucosal immune response. Adv Exp Med Biol 1989; 251: 191-202
-
(1989)
Adv Exp Med Biol
, vol.251
, pp. 191-202
-
-
Eldridge, J.H.1
Meulbroek, J.A.2
Staas, J.K.3
-
133
-
-
84864645051
-
Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection
-
Zhu Q, Talton J, Zhang G, et al. Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nat Med 2012; 18: 1291-6
-
(2012)
Nat Med
, vol.18
, pp. 1291-1296
-
-
Zhu, Q.1
Talton, J.2
Zhang, G.3
-
134
-
-
0031467095
-
The role of M cells in the protection of mucosal membranes
-
Gebert A. The role of M cells in the protection of mucosal membranes. Histochem Cell Biol 1997; 108: 455-70
-
(1997)
Histochem Cell Biol
, vol.108
, pp. 455-470
-
-
Gebert, A.1
-
135
-
-
0030959647
-
Ontogenetic development and distribution of antibody transport and Fc receptor mRNA expression in rat intestine
-
Martín MG, Wu SV, Walsh JH. Ontogenetic development and distribution of antibody transport and Fc receptor mRNA expression in rat intestine. Dig Dis Sci 1997; 42: 1062-9
-
(1997)
Dig Dis Sci
, vol.42
, pp. 1062-1069
-
-
Martín, M.G.1
Wu, S.V.2
Walsh, J.H.3
|