-
1
-
-
84870680872
-
The nanomedicine revolution, part 3: regulatory and safety challenges
-
Ventola CL. The nanomedicine revolution, part 3: regulatory and safety challenges. Pharm Ther 2012; 37: 632-9.
-
(2012)
Pharm Ther
, vol.37
, pp. 632-639
-
-
Ventola, C.L.1
-
3
-
-
33746985456
-
Polymer therapeutics-polymers as drugs, drug and protein conjugates and gene delivery systems: past, present and future opportunities
-
Duncan R, Ringsdorf H, Satchi-Fainaro R. Polymer therapeutics-polymers as drugs, drug and protein conjugates and gene delivery systems: past, present and future opportunities. J Drug Target 2006; 14: 337-41.
-
(2006)
J Drug Target
, vol.14
, pp. 337-341
-
-
Duncan, R.1
Ringsdorf, H.2
Satchi-Fainaro, R.3
-
4
-
-
0016622773
-
Structure and properties of pharmacologically active polymers
-
Ringsdorf H. Structure and properties of pharmacologically active polymers. J Appl Polym Sci Symp 1975; 51: 135-53.
-
(1975)
J Appl Polym Sci Symp
, vol.51
, pp. 135-153
-
-
Ringsdorf, H.1
-
5
-
-
0038387390
-
The dawning era of polymer therapeutics
-
Duncan R. The dawning era of polymer therapeutics. Nature Rev 2003; 2: 347-60.
-
(2003)
Nature Rev
, vol.2
, pp. 347-360
-
-
Duncan, R.1
-
6
-
-
33745461665
-
Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties
-
Nijhara R, Balakrishnan K. Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties. Nanomedicine 2006; 2: 127-36.
-
(2006)
Nanomedicine
, vol.2
, pp. 127-136
-
-
Nijhara, R.1
Balakrishnan, K.2
-
7
-
-
79955812915
-
Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review
-
Tyner K, Sadrieh N. Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review. Methods Mol Biol 2011; 697: 17-31.
-
(2011)
Methods Mol Biol
, vol.697
, pp. 17-31
-
-
Tyner, K.1
Sadrieh, N.2
-
9
-
-
84875167951
-
Dendrimer and cancer: a patent review (2006-present)
-
Cai X, Hu J, Xiao J, Cheng Y. Dendrimer and cancer: a patent review (2006-present). Expert Opin Ther Pat 2013; 23: 515-29.
-
(2013)
Expert Opin Ther Pat
, vol.23
, pp. 515-529
-
-
Cai, X.1
Hu, J.2
Xiao, J.3
Cheng, Y.4
-
10
-
-
79953774517
-
Regulating nanomedicine - can the FDA handle it?
-
Bawa R. Regulating nanomedicine - can the FDA handle it? Curr Drug Deliv 2011; 8: 227-34.
-
(2011)
Curr Drug Deliv
, vol.8
, pp. 227-234
-
-
Bawa, R.1
-
11
-
-
79957745191
-
Nanotechnology and nanomedicine for healthcare: challenges in translating innovations from bench to bedside
-
Bellare JR. Nanotechnology and nanomedicine for healthcare: challenges in translating innovations from bench to bedside. J Biomed Nanotechnol 2011; 7: 36-7.
-
(2011)
J Biomed Nanotechnol
, vol.7
, pp. 36-37
-
-
Bellare, J.R.1
-
14
-
-
79959872019
-
Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles
-
Valencia PM, Hanewich-Hollatz MH, Gao W et al. Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles. Biomaterials 2011; 32: 6226-33.
-
(2011)
Biomaterials
, vol.32
, pp. 6226-6233
-
-
Valencia, P.M.1
Hanewich-Hollatz, M.H.2
Gao, W.3
-
15
-
-
0035937592
-
Block copolymer micelles for drug delivery: design, characterization and biological significance
-
Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv Drug Deliv Rev 2001; 47: 113-31.
-
(2001)
Adv Drug Deliv Rev
, vol.47
, pp. 113-131
-
-
Kataoka, K.1
Harada, A.2
Nagasaki, Y.3
-
16
-
-
84911989810
-
-
6224898 (2001); 6475994 (2002); 6471968 (2002); 7005124 (2006).
-
Tomalia DA et al. U.S. Patents: 5714166 (1998); 6224898 (2001); 6475994 (2002); 6471968 (2002); 7005124 (2006).
-
(1998)
-
-
Tomalia, D.A.1
-
18
-
-
84911985377
-
A proposed taxonomy and classification strategy for well-defined, soft-matter nanoscale building blocks
-
Tomas T, Bottari G, eds. Hoboken, NJ: John Wiley & Sons
-
Christensen JB, Tomalia DA. A proposed taxonomy and classification strategy for well-defined, soft-matter nanoscale building blocks. In: Tomas T, Bottari G, eds. Organic Nanomaterials: Synthesis, Characterization, and Device Applications. Hoboken, NJ: John Wiley & Sons, 2013; 1-32.
-
(2013)
Organic Nanomaterials: Synthesis, Characterization, and Device Applications
, pp. 1-32
-
-
Christensen, J.B.1
Tomalia, D.A.2
-
19
-
-
0025373701
-
Starburst dendrimers: molecular level control of size, shape, surface chemistry, topology and flexibility from atoms to macroscopic matter
-
Tomalia DA, Naylor AM, Goddard WA III. Starburst dendrimers: molecular level control of size, shape, surface chemistry, topology and flexibility from atoms to macroscopic matter. Angew Chem Int Ed Engl 1990; 29: 138-75.
-
(1990)
Angew Chem Int Ed Engl
, vol.29
, pp. 138-175
-
-
Tomalia, D.A.1
Naylor, A.M.2
Goddard, W.A.3
-
20
-
-
68149173128
-
In quest of a systematic framework for unifying and defining nanoscience
-
Tomalia DA. In quest of a systematic framework for unifying and defining nanoscience. J Nanopart Res 2009; 11: 1251-310.
-
(2009)
J Nanopart Res
, vol.11
, pp. 1251-1310
-
-
Tomalia, D.A.1
-
21
-
-
75949118217
-
Dendrons/Dendrimer: quantized, nano-element like building blocks for soft-soft and soft-hard nano-compound synthesis
-
Tomalia DA. Dendrons/Dendrimer: quantized, nano-element like building blocks for soft-soft and soft-hard nano-compound synthesis. Soft Matter 2010; 6: 456-74.
-
(2010)
Soft Matter
, vol.6
, pp. 456-474
-
-
Tomalia, D.A.1
-
22
-
-
85010280679
-
-
New York, NY: Cambridge University Press
-
Tomalia DA, Christensen JB, Boas U. Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future. New York, NY: Cambridge University Press, 2012.
-
(2012)
Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future
-
-
Tomalia, D.A.1
Christensen, J.B.2
Boas, U.3
-
23
-
-
84893685184
-
In quest of a systematic framework for unifying and defining nanoscience
-
1430002-1-47
-
Tomalia DA, Khanna SN. In quest of a systematic framework for unifying and defining nanoscience. Mod Phys Lett B 2014; 28: 1430002-1-47.
-
(2014)
Mod Phys Lett B
, vol.28
-
-
Tomalia, D.A.1
Khanna, S.N.2
-
25
-
-
0026470988
-
Directed molecular evolution
-
Joyce GF. Directed molecular evolution. Sci Am 1992; 267: 90-7.
-
(1992)
Sci Am
, vol.267
, pp. 90-97
-
-
Joyce, G.F.1
-
26
-
-
0037062978
-
The antiquity of RNA-based evolution
-
Joyce GF. The antiquity of RNA-based evolution. Nature 2002; 418: 214-21.
-
(2002)
Nature
, vol.418
, pp. 214-221
-
-
Joyce, G.F.1
-
27
-
-
84864425311
-
The dendritic effect
-
New York, NY: Cambridge University Press
-
Tomalia DA, Christensen JB, Boas U, eds. The dendritic effect. In: Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future. New York, NY: Cambridge University Press, 2012; 276-92.
-
(2012)
Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future
, pp. 276-292
-
-
Tomalia, D.A.1
Christensen, J.B.2
Boas, U.e.3
-
28
-
-
84907515191
-
Dendrimers as quantized nano-modules in the nanotechnology field
-
Hoboken, NJ: John Wiley & Sons
-
Christensen JB, Tomalia DA. Dendrimers as quantized nano-modules in the nanotechnology field. In: Designing Dendrimers. Hoboken, NJ: John Wiley & Sons, 2012; 1-33.
-
(2012)
Designing Dendrimers
, pp. 1-33
-
-
Christensen, J.B.1
Tomalia, D.A.2
-
29
-
-
84898919503
-
Precision synthesis of subnanoparticles using dendrimers as a superatom synthesizer
-
Yamamoto K, Imaoka T. Precision synthesis of subnanoparticles using dendrimers as a superatom synthesizer. Acc Chem Res 2014; 47: 1127-36.
-
(2014)
Acc Chem Res
, vol.47
, pp. 1127-1136
-
-
Yamamoto, K.1
Imaoka, T.2
-
30
-
-
85050577752
-
Developing superatom science
-
Kemsley J. Developing superatom science. Chem Eng News 2013; 2013: 24-5.
-
(2013)
Chem Eng News
, vol.2013
, pp. 24-25
-
-
Kemsley, J.1
-
31
-
-
0033614097
-
Tobacco mosiac virus particle structure and the initiation of disassembly
-
Klug A. Tobacco mosiac virus particle structure and the initiation of disassembly. Phil Trans R Soc Lond B 1999; 354: 531-5.
-
(1999)
Phil Trans R Soc Lond B
, vol.354
, pp. 531-535
-
-
Klug, A.1
-
32
-
-
84985631191
-
From macromolecules to biological assemblies (Nobel lecture)
-
Klug A. From macromolecules to biological assemblies (Nobel lecture). Angew Chem Int Ed 1983; 22: 565-82.
-
(1983)
Angew Chem Int Ed
, vol.22
, pp. 565-582
-
-
Klug, A.1
-
33
-
-
77951877325
-
Conscripts of the infinite armada: systemic cancer therapy using nanomaterials
-
Scheinberg DA, Villa CH, Escorcia FE, McDevitt MR. Conscripts of the infinite armada: systemic cancer therapy using nanomaterials. Nat Rev 2010; 7: 266-76.
-
(2010)
Nat Rev
, vol.7
, pp. 266-276
-
-
Scheinberg, D.A.1
Villa, C.H.2
Escorcia, F.E.3
McDevitt, M.R.4
-
34
-
-
79959874185
-
Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations
-
Wijagkanalan W, Kawakami S, Hashida M. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharm Res 2011; 28: 1500-19.
-
(2011)
Pharm Res
, vol.28
, pp. 1500-1519
-
-
Wijagkanalan, W.1
Kawakami, S.2
Hashida, M.3
-
35
-
-
0036844787
-
Predicting blood-brain barrier partitioning of organic molecules using membrane-interaction QSAR analysis
-
Iyer M, Mishra R, Han Y, Hopfinger AJ. Predicting blood-brain barrier partitioning of organic molecules using membrane-interaction QSAR analysis. Pharm Res 2002; 19: 1611-21.
-
(2002)
Pharm Res
, vol.19
, pp. 1611-1621
-
-
Iyer, M.1
Mishra, R.2
Han, Y.3
Hopfinger, A.J.4
-
36
-
-
79960733045
-
Interactions of poly(amidoamine) dendrimers with human serum albumin: Binding constants and mechanisms
-
Giri J, Diallo MS, Simpson AJ, Goddard WA III, Kumar R, Woods GC. Interactions of poly(amidoamine) dendrimers with human serum albumin: Binding constants and mechanisms. ACS Nano 2011; 5: 3456-68.
-
(2011)
ACS Nano
, vol.5
, pp. 3456-3468
-
-
Giri, J.1
Diallo, M.S.2
Simpson, A.J.3
Goddard, W.A.4
Kumar, R.5
Woods, G.C.6
-
37
-
-
77958599623
-
The influence of dendron's architecture on the "rigid" and "flexible" behaviour in binding DNA-a modelling study
-
Pavan GM, Danini A. The influence of dendron's architecture on the "rigid" and "flexible" behaviour in binding DNA-a modelling study. Phys Chem Chem Phys 2010; 1: 13914-7.
-
(2010)
Phys Chem Chem Phys
, vol.1
, pp. 13914-13917
-
-
Pavan, G.M.1
Danini, A.2
-
38
-
-
84871952514
-
Theoretical and computational studies of dendrimers as delivery vectors
-
Tian W, Ma Y. Theoretical and computational studies of dendrimers as delivery vectors. Chem Soc Rev 2013; 42: 705-27.
-
(2013)
Chem Soc Rev
, vol.42
, pp. 705-727
-
-
Tian, W.1
Ma, Y.2
-
39
-
-
84873718392
-
Physicochemical properties determine nanomaterial cellular uptake, transport, and fate
-
Zhu M, Nie G, Meng H, Xia T, Nel A, Zhao Y. Physicochemical properties determine nanomaterial cellular uptake, transport, and fate. Acc Chem Res 2013; 46: 622-31.
-
(2013)
Acc Chem Res
, vol.46
, pp. 622-631
-
-
Zhu, M.1
Nie, G.2
Meng, H.3
Xia, T.4
Nel, A.5
Zhao, Y.6
-
40
-
-
79959811662
-
Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism
-
Meng H, Yang S, Li Z et al. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. ACS Nano 2011; 5: 4434-47.
-
(2011)
ACS Nano
, vol.5
, pp. 4434-4447
-
-
Meng, H.1
Yang, S.2
Li, Z.3
-
41
-
-
36749045172
-
The molecular architecture of the nuclear pore complex
-
Alber F, Dokudovskaya S, Veenhoff LM et al. The molecular architecture of the nuclear pore complex. Nature 2007; 450: 695-701.
-
(2007)
Nature
, vol.450
, pp. 695-701
-
-
Alber, F.1
Dokudovskaya, S.2
Veenhoff, L.M.3
-
42
-
-
78049323834
-
Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future
-
Gil PR, Oberdorster G, Elder A, Puntes V, Parak WJ. Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. ACS Nano 2010; 4: 5527-31.
-
(2010)
ACS Nano
, vol.4
, pp. 5527-5531
-
-
Gil, P.R.1
Oberdorster, G.2
Elder, A.3
Puntes, V.4
Parak, W.J.5
-
43
-
-
81855198887
-
Factors controlling nanoparticles pharmacokinetics: an integrated analysis and perspective
-
Moghimi SM, Hunter AC, Andresen TL. Factors controlling nanoparticles pharmacokinetics: an integrated analysis and perspective. Annu Rev Pharmacol Toxicol 2012; 52: 481-503.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 481-503
-
-
Moghimi, S.M.1
Hunter, A.C.2
Andresen, T.L.3
-
44
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
-
Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000; 65: 271-84.
-
(2000)
J Control Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
45
-
-
33847017288
-
Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
-
Tomalia DA, Reyna LA, Svenson S. Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem Soc Trans 2007; 35: 61-7.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 61-67
-
-
Tomalia, D.A.1
Reyna, L.A.2
Svenson, S.3
-
46
-
-
35148864458
-
Renal clearance of quantum dots
-
Choi HS, Liu W, Misra P et al. Renal clearance of quantum dots. Nat Biotechnol 2007; 25: 1165-70.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1165-1170
-
-
Choi, H.S.1
Liu, W.2
Misra, P.3
-
47
-
-
61649102498
-
Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine
-
Burns AA, Vider J, Ow H et al. Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine. Nano Lett 2009; 9: 442-8.
-
(2009)
Nano Lett
, vol.9
, pp. 442-448
-
-
Burns, A.A.1
Vider, J.2
Ow, H.3
-
49
-
-
78649538085
-
Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering
-
Hamad I, Al-Hanbali O, Hunger AC, Rutt KJ, Andresen TL, Moghimi SM. Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering. ACS Nano 2010; 4: 6629-38.
-
(2010)
ACS Nano
, vol.4
, pp. 6629-6638
-
-
Hamad, I.1
Al-Hanbali, O.2
Hunger, A.C.3
Rutt, K.J.4
Andresen, T.L.5
Moghimi, S.M.6
-
50
-
-
77952563342
-
What the cell "sees" in bionanoscience
-
Walczyk D, Bombelli BB, Monopoli MP, Lynch I, Dawson KA. What the cell "sees" in bionanoscience. J Am Chem Soc 2010; 132: 5761-8.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 5761-5768
-
-
Walczyk, D.1
Bombelli, B.B.2
Monopoli, M.P.3
Lynch, I.4
Dawson, K.A.5
-
51
-
-
68649116329
-
Stoichiometry and structure of poly(amidoamine) dendrimer-lipid complexes
-
Kelly CV, Liroff MG, Triplett LD et al. Stoichiometry and structure of poly(amidoamine) dendrimer-lipid complexes. ACS Nano 2009; 3: 1886-96.
-
(2009)
ACS Nano
, vol.3
, pp. 1886-1896
-
-
Kelly, C.V.1
Liroff, M.G.2
Triplett, L.D.3
-
52
-
-
36049015878
-
Size-dependent cytoxocity of gold nanoparticles
-
Pan Y, Neuss S, Leifert A et al. Size-dependent cytoxocity of gold nanoparticles. Small 2007; 3: 1941-9.
-
(2007)
Small
, vol.3
, pp. 1941-1949
-
-
Pan, Y.1
Neuss, S.2
Leifert, A.3
-
53
-
-
83555166219
-
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
-
Cabral H, Matsumoto Y, Mizuno K et al. Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 2011; 6: 815-23.
-
(2011)
Nat Nanotechnol
, vol.6
, pp. 815-823
-
-
Cabral, H.1
Matsumoto, Y.2
Mizuno, K.3
-
54
-
-
0024470863
-
Influence of vesicle size, lipid composition and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice
-
Mayer LD, Tai LCL, Ko DSC et al. Influence of vesicle size, lipid composition and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice. Cancer Res 1989; 49: 5922-30.
-
(1989)
Cancer Res
, vol.49
, pp. 5922-5930
-
-
Mayer, L.D.1
Tai, L.C.L.2
Ko, D.S.C.3
-
55
-
-
84874636369
-
Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates
-
Tang L, Gabrielson NP, Uckun FM, Fan TM, Cheng J. Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates. Mol Pharm 2013; 10: 883-92.
-
(2013)
Mol Pharm
, vol.10
, pp. 883-892
-
-
Tang, L.1
Gabrielson, N.P.2
Uckun, F.M.3
Fan, T.M.4
Cheng, J.5
-
56
-
-
84881442222
-
Size-dependent biodistribution and antitumor efficacy of polymer micelle drug delivery systems
-
Yue J, Liu S, Xie Z, Xing Y, Jing X. Size-dependent biodistribution and antitumor efficacy of polymer micelle drug delivery systems. J Mater Chem B 2013; 1: 4273-80.
-
(2013)
J Mater Chem B
, vol.1
, pp. 4273-4280
-
-
Yue, J.1
Liu, S.2
Xie, Z.3
Xing, Y.4
Jing, X.5
-
57
-
-
0029006392
-
Effect of the non-cross-resistant anthracycline annamycin incorporated in liposomes
-
Zou YY, Ling YH, Reddy ST, Priebe W, Perezsoler R. Effect of the non-cross-resistant anthracycline annamycin incorporated in liposomes. Int J Cancer 1995; 61: 666-71.
-
(1995)
Int J Cancer
, vol.61
, pp. 666-671
-
-
Zou, Y.Y.1
Ling, Y.H.2
Reddy, S.T.3
Priebe, W.4
Perezsoler, R.5
-
58
-
-
77955251549
-
The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles
-
Lee H, Fonge H, Hoang B, Reilly RM, Allen C. The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles. Mol Pharm 2010; 7: 1195-208.
-
(2010)
Mol Pharm
, vol.7
, pp. 1195-1208
-
-
Lee, H.1
Fonge, H.2
Hoang, B.3
Reilly, R.M.4
Allen, C.5
-
59
-
-
84864722016
-
Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates
-
Tang L, Fan TM, Borst LB, Cheng JJ. Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. ACS Nano 2012; 6: 3954-66.
-
(2012)
ACS Nano
, vol.6
, pp. 3954-3966
-
-
Tang, L.1
Fan, T.M.2
Borst, L.B.3
Cheng, J.J.4
-
60
-
-
84896696928
-
Heterogeneity in nanoparticles influences biodistribution and targeting
-
Adjei IM, Peetla C, Labhasetwar V. Heterogeneity in nanoparticles influences biodistribution and targeting. Nanomedicine 2014; 9: 267-78.
-
(2014)
Nanomedicine
, vol.9
, pp. 267-278
-
-
Adjei, I.M.1
Peetla, C.2
Labhasetwar, V.3
-
61
-
-
84886310583
-
Strategies for advancing cancer nanomedicine
-
Chauhan VP, Jain RK. Strategies for advancing cancer nanomedicine. Nat Mater 2013; 12: 958-62.
-
(2013)
Nat Mater
, vol.12
, pp. 958-962
-
-
Chauhan, V.P.1
Jain, R.K.2
-
63
-
-
46949106134
-
The long and short of carbon nanotube toxicity
-
Kostarelos K. The long and short of carbon nanotube toxicity. Nat Biotechnol 2008; 7: 774-5.
-
(2008)
Nat Biotechnol
, vol.7
, pp. 774-775
-
-
Kostarelos, K.1
-
64
-
-
38849152834
-
Dynamic imaging of functionalized multi-walled carbon nanotube systemic circulation and urinary excretion
-
Lacerda L, Soundararajan A, Singh R et al. Dynamic imaging of functionalized multi-walled carbon nanotube systemic circulation and urinary excretion. Adv Mater 2008; 20: 225-30.
-
(2008)
Adv Mater
, vol.20
, pp. 225-230
-
-
Lacerda, L.1
Soundararajan, A.2
Singh, R.3
-
65
-
-
80054048527
-
Gold nanoparticles: a revival in precious metal administration to patients
-
Thakor AS, Jokerst J, Zavaleta C, Massoud TF, Gambhir SS. Gold nanoparticles: a revival in precious metal administration to patients. Nano Lett 2011; 11: 4029-36.
-
(2011)
Nano Lett
, vol.11
, pp. 4029-4036
-
-
Thakor, A.S.1
Jokerst, J.2
Zavaleta, C.3
Massoud, T.F.4
Gambhir, S.S.5
-
66
-
-
81755187274
-
Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration
-
Chauhan VP, Popović Z, Chen O et al. Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. Angew Chem Int Ed 2011; 50: 11417-20.
-
(2011)
Angew Chem Int Ed
, vol.50
, pp. 11417-11420
-
-
Chauhan, V.P.1
Popović, Z.2
Chen, O.3
-
67
-
-
84879459400
-
Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft
-
Chu KS, Hasan W, Rawal S et al. Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft. Nanomed Nanotechnol Biol Med 2013; 9: 686-93.
-
(2013)
Nanomed Nanotechnol Biol Med
, vol.9
, pp. 686-693
-
-
Chu, K.S.1
Hasan, W.2
Rawal, S.3
-
68
-
-
34248402413
-
Shape effects of filaments versus spherical particles in flow and drug delivery
-
Geng Y, Dalhaimer P, Cai S et al. Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol 2007; 2: 249-55.
-
(2007)
Nat Nanotechnol
, vol.2
, pp. 249-255
-
-
Geng, Y.1
Dalhaimer, P.2
Cai, S.3
-
69
-
-
84877625601
-
Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery
-
Zhou Z, Ma X, Jin E et al. Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery. Biomaterials 2013; 34: 5722-35.
-
(2013)
Biomaterials
, vol.34
, pp. 5722-5735
-
-
Zhou, Z.1
Ma, X.2
Jin, E.3
-
70
-
-
84874403157
-
Single-walled carbon nanotube surface control of complement recognition and activation
-
Anderson AJ, Robinson JT, Dai H, Hunter AC, Andresen TL, Moghimi SM. Single-walled carbon nanotube surface control of complement recognition and activation. ACS Nano 2013; 7: 1108-19.
-
(2013)
ACS Nano
, vol.7
, pp. 1108-1119
-
-
Anderson, A.J.1
Robinson, J.T.2
Dai, H.3
Hunter, A.C.4
Andresen, T.L.5
Moghimi, S.M.6
-
71
-
-
84858042094
-
Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro
-
Dobrovolskaia MA, Patri AK, Simak J et al. Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro. Mol Pharm 2012; 9: 382-93.
-
(2012)
Mol Pharm
, vol.9
, pp. 382-393
-
-
Dobrovolskaia, M.A.1
Patri, A.K.2
Simak, J.3
-
72
-
-
84896535996
-
How to study dendrimers and dendriplexes III. Biodistribution, pharmacokinetics and toxicity in vivo
-
Shcharbin D, Janaszewska A, Klajnert-Maculewicz B et al. How to study dendrimers and dendriplexes III. Biodistribution, pharmacokinetics and toxicity in vivo. J Control Release 2014; 181: 40-52.
-
(2014)
J Control Release
, vol.181
, pp. 40-52
-
-
Shcharbin, D.1
Janaszewska, A.2
Klajnert-Maculewicz, B.3
-
73
-
-
84894608275
-
Oligo(ethylene glycol)-based thermosensitive dendrimers and their tumor accumulation and penetration
-
Wu W, Driessen W, Jiang X. Oligo(ethylene glycol)-based thermosensitive dendrimers and their tumor accumulation and penetration. J Am Chem Soc 2014; 136: 3145-55.
-
(2014)
J Am Chem Soc
, vol.136
, pp. 3145-3155
-
-
Wu, W.1
Driessen, W.2
Jiang, X.3
-
74
-
-
84897025238
-
Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion
-
Lagunas A, Castaño AG, Artés JM et al. Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion. Nano Res 2014; 7: 399-409.
-
(2014)
Nano Res
, vol.7
, pp. 399-409
-
-
Lagunas, A.1
Castaño, A.G.2
Artés, J.M.3
-
75
-
-
84859761719
-
Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
-
Sadekar S, Ghandehari H. Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery. Adv Drug Deliv Rev 2012; 64: 571-88.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 571-588
-
-
Sadekar, S.1
Ghandehari, H.2
-
76
-
-
46549084447
-
The effect of surface functionality on cellular trafficking of dendrimers
-
Perumal OP, Inapagolla R, Kannan S, Kannan RM. The effect of surface functionality on cellular trafficking of dendrimers. Biomaterals 2008; 29: 3469-76.
-
(2008)
Biomaterals
, vol.29
, pp. 3469-3476
-
-
Perumal, O.P.1
Inapagolla, R.2
Kannan, S.3
Kannan, R.M.4
-
77
-
-
33645464504
-
Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines
-
Gurdag S, Khandare J, Stapels S, Matherly LH, Kannan RM. Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines. Bioconjug Chem 2006; 17: 275-83.
-
(2006)
Bioconjug Chem
, vol.17
, pp. 275-283
-
-
Gurdag, S.1
Khandare, J.2
Stapels, S.3
Matherly, L.H.4
Kannan, R.M.5
-
78
-
-
0030293017
-
In vitro gene delivery by degraded polyamidoamine dendrimers
-
Tang MX, Redemann CT, Szoka FC. In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug Chem 1996; 7: 703-14.
-
(1996)
Bioconjug Chem
, vol.7
, pp. 703-714
-
-
Tang, M.X.1
Redemann, C.T.2
Szoka, F.C.3
-
79
-
-
84555186724
-
Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus
-
Liu X, Wu J, Yamine M et al. Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus. Bioconjug Chem 2011; 22: 2461-73.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 2461-2473
-
-
Liu, X.1
Wu, J.2
Yamine, M.3
-
80
-
-
84894288569
-
Nanodynamics of dendritic core-multishell nanocarriers
-
Boreham A, Pfaff M, Fleige E, Haag R, Alexiev U. Nanodynamics of dendritic core-multishell nanocarriers. Langmuir 2014; 30: 1686-95.
-
(2014)
Langmuir
, vol.30
, pp. 1686-1695
-
-
Boreham, A.1
Pfaff, M.2
Fleige, E.3
Haag, R.4
Alexiev, U.5
-
82
-
-
84894856234
-
A novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis invivo
-
Reebye V, Sætrom PI, Mintz PJ et al. A novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis invivo. Hepatology 2014; 59: 216-27.
-
(2014)
Hepatology
, vol.59
, pp. 216-227
-
-
Reebye, V.1
Sætrom, P.I.2
Mintz, P.J.3
-
83
-
-
84885386826
-
Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: a concise overview
-
Mignami S, El Kazzouli S, Bousmina M, Majoral J-P. Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: a concise overview. Adv Drug Deliv Rev 2013; 65: 1316-30.
-
(2013)
Adv Drug Deliv Rev
, vol.65
, pp. 1316-1330
-
-
Mignami, S.1
El Kazzouli, S.2
Bousmina, M.3
Majoral, J.-P.4
-
84
-
-
84856540364
-
Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs)
-
Tomalia DA. Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs). New J Chem 2012; 36: 264-81.
-
(2012)
New J Chem
, vol.36
, pp. 264-281
-
-
Tomalia, D.A.1
-
85
-
-
0021586266
-
A new class of polymers: starburst dendritic macromolecules
-
Tomalia DA, Baker H, Dewald J et al. A new class of polymers: starburst dendritic macromolecules. Polym J (Tokyo) 1985; 17: 117-32.
-
(1985)
Polym J (Tokyo)
, vol.17
, pp. 117-132
-
-
Tomalia, D.A.1
Baker, H.2
Dewald, J.3
-
86
-
-
0037103007
-
Discovery of dendrimers and dendritic polymers: a brief historical perspective
-
Tomalia DA, Fréchet JMJ. Discovery of dendrimers and dendritic polymers: a brief historical perspective. J Polym Sci A Polym Chem 2002; 40: 2719-28.
-
(2002)
J Polym Sci A Polym Chem
, vol.40
, pp. 2719-2728
-
-
Tomalia, D.A.1
Fréchet, J.M.J.2
-
87
-
-
73249139071
-
Dendron-mediated self-assembly, disassembly, and self-organization of complex systems
-
Rosen BM, Wilson CJ, Wilson DA, Peterca M, Imam MR, Percec V. Dendron-mediated self-assembly, disassembly, and self-organization of complex systems. Chem Rev 2009; 109: 6275-540.
-
(2009)
Chem Rev
, vol.109
, pp. 6275-6540
-
-
Rosen, B.M.1
Wilson, C.J.2
Wilson, D.A.3
Peterca, M.4
Imam, M.R.5
Percec, V.6
-
88
-
-
84861226527
-
Triazine dendrimers as drug delivery systems: from synthesis to therapy
-
Lim J, Simanek EE. Triazine dendrimers as drug delivery systems: from synthesis to therapy. Adv Drug Deliv Rev 2012; 64: 826-35.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 826-835
-
-
Lim, J.1
Simanek, E.E.2
-
89
-
-
77957827161
-
Poly propyl ether imine (PETIM) dendrimer: a novel non-toxic dendrimer for sustained drug delivery
-
Jain S, Kaur A, Puri R et al. Poly propyl ether imine (PETIM) dendrimer: a novel non-toxic dendrimer for sustained drug delivery. Eur J Med Chem 2010; 45: 4997-5005.
-
(2010)
Eur J Med Chem
, vol.45
, pp. 4997-5005
-
-
Jain, S.1
Kaur, A.2
Puri, R.3
-
90
-
-
0035342007
-
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
-
Esfand R, Tomalia DA. Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discovery Today 2001; 6: 427-36.
-
(2001)
Drug Discovery Today
, vol.6
, pp. 427-436
-
-
Esfand, R.1
Tomalia, D.A.2
-
91
-
-
0037493690
-
Interaction of dendrimers (artificial proteins) with hydroxyapatite crystals
-
Chen H, Banaszak Holl M, Orr B, Majoros I, Clarkson BH. Interaction of dendrimers (artificial proteins) with hydroxyapatite crystals. J Dent Res 2003; 82: 443-8.
-
(2003)
J Dent Res
, vol.82
, pp. 443-448
-
-
Chen, H.1
Banaszak Holl, M.2
Orr, B.3
Majoros, I.4
Clarkson, B.H.5
-
92
-
-
84873292926
-
Orthogonality in organic, polymer, and supramolecular chemistry: from Merrifield to click chemistry
-
Wong C-H, Zimmerman SC. Orthogonality in organic, polymer, and supramolecular chemistry: from Merrifield to click chemistry. Chem Commun 2013; 49: 1679-95.
-
(2013)
Chem Commun
, vol.49
, pp. 1679-1695
-
-
Wong, C.-H.1
Zimmerman, S.C.2
-
93
-
-
0030682417
-
A contemporary survey of covalent connectivity and complexity. The divergent synthesis of poly(thioether) dendrimers. Amplified, genealogical directed synthesis leading to the de gennes dense packed state
-
Lothian-Tomalia MK, Hedstrand DM, Tomalia DA. A contemporary survey of covalent connectivity and complexity. The divergent synthesis of poly(thioether) dendrimers. Amplified, genealogical directed synthesis leading to the de gennes dense packed state. Tetrahedron 1997; 53: 15495-513.
-
(1997)
Tetrahedron
, vol.53
, pp. 15495-15513
-
-
Lothian-Tomalia, M.K.1
Hedstrand, D.M.2
Tomalia, D.A.3
-
95
-
-
73249130570
-
Applications of orthogonal "click" chemistries in the synthesis of functional soft materials
-
Iha RK, Wooley KL, Nystrom AM, Burke DJ, Kade MJ, Hawker CJ. Applications of orthogonal "click" chemistries in the synthesis of functional soft materials. Chem Rev 2009; 109: 5620-86.
-
(2009)
Chem Rev
, vol.109
, pp. 5620-5686
-
-
Iha, R.K.1
Wooley, K.L.2
Nystrom, A.M.3
Burke, D.J.4
Kade, M.J.5
Hawker, C.J.6
-
96
-
-
77954314881
-
Designing dendritic frameworks using versatile building blocks suitable for CuI-catalyzed alkyne azide click chemistry
-
Hourani R, Sharma A, Kakkar A. Designing dendritic frameworks using versatile building blocks suitable for CuI-catalyzed alkyne azide click chemistry. Tetrahedron Lett 2010; 51: 3792-5.
-
(2010)
Tetrahedron Lett
, vol.51
, pp. 3792-3795
-
-
Hourani, R.1
Sharma, A.2
Kakkar, A.3
-
97
-
-
0037959570
-
Structure control within poly(amidoamine) dendrimers: size, shape and regio-chemical mimicry of globular proteins
-
Tomalia DA, Huang B, Swanson DR, Brothers HM II, Klimash JW. Structure control within poly(amidoamine) dendrimers: size, shape and regio-chemical mimicry of globular proteins. Tetrahedron 2003; 59: 3799-813.
-
(2003)
Tetrahedron
, vol.59
, pp. 3799-3813
-
-
Tomalia, D.A.1
Huang, B.2
Swanson, D.R.3
Brothers, H.M.4
Klimash, J.W.5
-
98
-
-
84862557067
-
Simplifying the synthesis of dendrimers: accelerated approaches
-
Walter MV, Malkoch M. Simplifying the synthesis of dendrimers: accelerated approaches. Chem Soc Rev 2012; 41: 4593-609.
-
(2012)
Chem Soc Rev
, vol.41
, pp. 4593-4609
-
-
Walter, M.V.1
Malkoch, M.2
-
99
-
-
18444392735
-
Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry
-
Tomalia DA. Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog Polym Sci 2005; 30: 294-324.
-
(2005)
Prog Polym Sci
, vol.30
, pp. 294-324
-
-
Tomalia, D.A.1
-
100
-
-
79953716272
-
Clinically relevant anticancer polymer paclitaxel therapeutics
-
Yang D, Yu L, Van S. Clinically relevant anticancer polymer paclitaxel therapeutics. Cancers 2011; 3: 17-42.
-
(2011)
Cancers
, vol.3
, pp. 17-42
-
-
Yang, D.1
Yu, L.2
Van, S.3
-
101
-
-
84874075020
-
A versatile polymer micelle drug delivery system for encapsulation and in vivo stabilization of hydrophobic anticancer drugs
-
Rios-Doria J, Carie A, Costich T et al. A versatile polymer micelle drug delivery system for encapsulation and in vivo stabilization of hydrophobic anticancer drugs. J Drug Deliv 2012; 2012: 1-8.
-
(2012)
J Drug Deliv
, vol.2012
, pp. 1-8
-
-
Rios-Doria, J.1
Carie, A.2
Costich, T.3
-
103
-
-
84898872381
-
Isolation and characterization of precise dye/dendrimer ratios
-
Dougherty CA, Furgal JC, Van Dongen MA et al. Isolation and characterization of precise dye/dendrimer ratios. Chem Eur J 2014; 20: 1-9.
-
(2014)
Chem Eur J
, vol.20
, pp. 1-9
-
-
Dougherty, C.A.1
Furgal, J.C.2
Van Dongen, M.A.3
-
104
-
-
84856716430
-
Exponential diagnostic signal amplification via dendritic chain reaction: the dendritic effect of a self-immolative amplifier component
-
Karton-Lifshin N, Shabat D. Exponential diagnostic signal amplification via dendritic chain reaction: the dendritic effect of a self-immolative amplifier component. New J Chem 2012; 36: 386-93.
-
(2012)
New J Chem
, vol.36
, pp. 386-393
-
-
Karton-Lifshin, N.1
Shabat, D.2
-
105
-
-
33750423606
-
Cationic poly-l-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats
-
Boyd BJ, Kaminskas LM, Karellas P, Krippner G, Lessene R, Porter CJH. Cationic poly-l-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats. Mol Pharm 2006; 3: 614-27.
-
(2006)
Mol Pharm
, vol.3
, pp. 614-627
-
-
Boyd, B.J.1
Kaminskas, L.M.2
Karellas, P.3
Krippner, G.4
Lessene, R.5
Porter, C.J.H.6
-
106
-
-
84868283684
-
Effect of size, surface charge, and hydrophobicity of poly(amidoamine) dendrimers on their skin penetration
-
Yang Y, Sunoqrot S, Stowell C et al. Effect of size, surface charge, and hydrophobicity of poly(amidoamine) dendrimers on their skin penetration. Biomacromolecules 2012; 13: 2154-62.
-
(2012)
Biomacromolecules
, vol.13
, pp. 2154-2162
-
-
Yang, Y.1
Sunoqrot, S.2
Stowell, C.3
-
108
-
-
77749297971
-
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
-
Olson ES, Jiang T, Aguilera TA et al. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc of the National Acad of Sci 2010; 107: 4311-6.
-
(2010)
Proc of the National Acad of Sci
, vol.107
, pp. 4311-4316
-
-
Olson, E.S.1
Jiang, T.2
Aguilera, T.A.3
-
109
-
-
80054769453
-
Theranostic nanoparticles engineered for clinic and pharmaceutics
-
Ma X, Zhao Y, Liang XJ. Theranostic nanoparticles engineered for clinic and pharmaceutics. Acc Chem Res 2011; 44: 1114-22.
-
(2011)
Acc Chem Res
, vol.44
, pp. 1114-1122
-
-
Ma, X.1
Zhao, Y.2
Liang, X.J.3
-
110
-
-
84874637808
-
Theranostics: are we there yet?
-
Svenson S. Theranostics: are we there yet? Mol Pharm 2012; 10: 848-56.
-
(2012)
Mol Pharm
, vol.10
, pp. 848-856
-
-
Svenson, S.1
-
111
-
-
84874619226
-
Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry
-
Lo S-T, Kumar A, Hsieh J-T, Sun X. Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry. Mol Pharm 2013; 10: 793-812.
-
(2013)
Mol Pharm
, vol.10
, pp. 793-812
-
-
Lo, S.-T.1
Kumar, A.2
Hsieh, J.-T.3
Sun, X.4
-
112
-
-
84893320082
-
Nanoparticles for multimodal in vivo imaging in nanomedicine
-
Key J, Leary JF. Nanoparticles for multimodal in vivo imaging in nanomedicine. Int J Nanomed 2014; 9: 711-26.
-
(2014)
Int J Nanomed
, vol.9
, pp. 711-726
-
-
Key, J.1
Leary, J.F.2
-
113
-
-
84888373686
-
A multifunctional theranostic platform based on phthalocyanine-loaded dendrimer for image-guided drug delivery and photodynamic therapy
-
Taratula O, Schumann C, Naleway MA, Pang AJ, Chon KJ. A multifunctional theranostic platform based on phthalocyanine-loaded dendrimer for image-guided drug delivery and photodynamic therapy. Mol Pharm 2013; 10: 3946-58.
-
(2013)
Mol Pharm
, vol.10
, pp. 3946-3958
-
-
Taratula, O.1
Schumann, C.2
Naleway, M.A.3
Pang, A.J.4
Chon, K.J.5
-
114
-
-
80054821668
-
Theranostics: combining imaging and therapy
-
Kelkar SS, Reineke TM. Theranostics: combining imaging and therapy. Bioconjug Chem 2011; 22: 1879-903.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 1879-1903
-
-
Kelkar, S.S.1
Reineke, T.M.2
-
115
-
-
80054766761
-
Cell-specific, activatable, and theranostic prodrug for dual-targeted cancer imaging and therapy
-
Santra S, Kaittanis C, Santiesteban OJ, Perez JM. Cell-specific, activatable, and theranostic prodrug for dual-targeted cancer imaging and therapy. J Am Chem Soc 2011; 133: 16680-8.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 16680-16688
-
-
Santra, S.1
Kaittanis, C.2
Santiesteban, O.J.3
Perez, J.M.4
-
116
-
-
84874643120
-
Special issue: theranostic nanomedicine with functional nanoarchitecture
-
Pan D. Special issue: theranostic nanomedicine with functional nanoarchitecture. Mol Pharm 2013; 10: 781-1150.
-
(2013)
Mol Pharm
, vol.10
, pp. 781-1150
-
-
Pan, D.1
-
117
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
Jiang T, Olson ES, Nguyen QT, Roy M, Jennings PA, Tsien RY. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc of the National Acad of Sci 2004; 101: 17867-72.
-
(2004)
Proc of the National Acad of Sci
, vol.101
, pp. 17867-17872
-
-
Jiang, T.1
Olson, E.S.2
Nguyen, Q.T.3
Roy, M.4
Jennings, P.A.5
Tsien, R.Y.6
-
118
-
-
77749254873
-
Surgery with molecular fluorescence imaging using activable cell-penetrating peptides decreases residual cancer and improves survival
-
Nguyen QT, Olson ES, Aguilera TA et al. Surgery with molecular fluorescence imaging using activable cell-penetrating peptides decreases residual cancer and improves survival. Proc of the National Acad of Sci 2010; 107: 4317-22.
-
(2010)
Proc of the National Acad of Sci
, vol.107
, pp. 4317-4322
-
-
Nguyen, Q.T.1
Olson, E.S.2
Aguilera, T.A.3
-
119
-
-
84874417298
-
In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity
-
Olson ES, Whitney MA, Friedman B et al. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol 2012; 4: 595-605.
-
(2012)
Integr Biol
, vol.4
, pp. 595-605
-
-
Olson, E.S.1
Whitney, M.A.2
Friedman, B.3
-
120
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
Duncan R, Izzo L. Dendrimer biocompatibility and toxicity. Adv Drug Deliv Rev 2005; 57: 2215-37.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
121
-
-
84870414034
-
Dendrimers and the development of new complex nanomaterials for biomedical applications
-
Gardikis K, Micha-Screttas M, Demetzos C, Steele BR. Dendrimers and the development of new complex nanomaterials for biomedical applications. Curr Med Chem 2012; 19: 4913-28.
-
(2012)
Curr Med Chem
, vol.19
, pp. 4913-4928
-
-
Gardikis, K.1
Micha-Screttas, M.2
Demetzos, C.3
Steele, B.R.4
-
122
-
-
84858679264
-
Multifunctional dendritic polymers in nanomedicine: opportunities and challenges
-
Khandare J, Calderon M, Dagia MN, Haag R. Multifunctional dendritic polymers in nanomedicine: opportunities and challenges. Chem Soc Rev 2012; 41: 2824-48.
-
(2012)
Chem Soc Rev
, vol.41
, pp. 2824-2848
-
-
Khandare, J.1
Calderon, M.2
Dagia, M.N.3
Haag, R.4
-
123
-
-
84876238782
-
Advances in applications of dendritic compounds
-
Ma N, Ma C, Deng Y, Wang T, He N. Advances in applications of dendritic compounds. J Nanosci Nanotechnol 2013; 19: 33-9.
-
(2013)
J Nanosci Nanotechnol
, vol.19
, pp. 33-39
-
-
Ma, N.1
Ma, C.2
Deng, Y.3
Wang, T.4
He, N.5
-
124
-
-
80052323457
-
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis
-
Thomas TP, Goonewardena SN, Majoros IJ et al. Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum 2011; 63: 2671-80.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2671-2680
-
-
Thomas, T.P.1
Goonewardena, S.N.2
Majoros, I.J.3
-
125
-
-
84884289033
-
Dendrimer-enabled DNA delivery and transformation of Chlamydia pneumoniae
-
Gerard HC, Mishra MJ, Mao G et al. Dendrimer-enabled DNA delivery and transformation of Chlamydia pneumoniae. Nanomed Nanotechnol Biol Med 2013; 9: 996-1008.
-
(2013)
Nanomed Nanotechnol Biol Med
, vol.9
, pp. 996-1008
-
-
Gerard, H.C.1
Mishra, M.J.2
Mao, G.3
-
126
-
-
84885068319
-
Dendrimer-enabled transformation of Chlamydia trachomatis
-
Kannan RM, Gerard HC, Mishra MK et al. Dendrimer-enabled transformation of Chlamydia trachomatis. Microb Pathog 2013; 65: 29-35.
-
(2013)
Microb Pathog
, vol.65
, pp. 29-35
-
-
Kannan, R.M.1
Gerard, H.C.2
Mishra, M.K.3
-
127
-
-
79955703641
-
A phosphorus-based dendrimer targets inflammation and dosteoclastogenesis in experimental arthritis
-
81ra35
-
Hayder M, Poupot M, Baron M et al. A phosphorus-based dendrimer targets inflammation and dosteoclastogenesis in experimental arthritis. Sci Transl Med 2011; 2011: 81ra35.
-
(2011)
Sci Transl Med
, vol.2011
-
-
Hayder, M.1
Poupot, M.2
Baron, M.3
-
128
-
-
11944272030
-
Solubility enhancement of indomethacin using dendrimer complex and bio-disposition profile of these complexes in arthiritic rats
-
Chauhan AS, Jain NK, Diwan PV, Khopade AJ. Solubility enhancement of indomethacin using dendrimer complex and bio-disposition profile of these complexes in arthiritic rats. J Drug Target 2004; 12: 575-83.
-
(2004)
J Drug Target
, vol.12
, pp. 575-583
-
-
Chauhan, A.S.1
Jain, N.K.2
Diwan, P.V.3
Khopade, A.J.4
-
129
-
-
66149083636
-
Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers
-
Chauhan AS, Diwan PV, Jain NK, Tomalia DA. Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers. Biomacromolecules 2009; 10: 1195-202.
-
(2009)
Biomacromolecules
, vol.10
, pp. 1195-1202
-
-
Chauhan, A.S.1
Diwan, P.V.2
Jain, N.K.3
Tomalia, D.A.4
-
130
-
-
77956885441
-
In vivo efficacy of dendrimer-methylprednisolone conjugate formulation for the treatment of lung inflammation
-
Inapagolla R, Guru BR, Kurtoglu KE et al. In vivo efficacy of dendrimer-methylprednisolone conjugate formulation for the treatment of lung inflammation. Int J Pharm 2010; 399: 140-7.
-
(2010)
Int J Pharm
, vol.399
, pp. 140-147
-
-
Inapagolla, R.1
Guru, B.R.2
Kurtoglu, K.E.3
-
131
-
-
84878464740
-
Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment
-
Blattes E, Vercellone A, Eutamène H et al. Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment. Proc Natl Acad Sci USA 2013; 110: 8795-800.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8795-8800
-
-
Blattes, E.1
Vercellone, A.2
Eutamène, H.3
-
132
-
-
81155152766
-
Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
-
Iezzi R, Guru BR, Glybina IV, Mishra MJ, Kennedy A, Kannan RM. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials 2012; 33: 979-88.
-
(2012)
Biomaterials
, vol.33
, pp. 979-988
-
-
Iezzi, R.1
Guru, B.R.2
Glybina, I.V.3
Mishra, M.J.4
Kennedy, A.5
Kannan, R.M.6
-
133
-
-
84860129964
-
Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model
-
130ra46
-
Kannan S, Dai H, Navath RS et al. Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model. Sci Transl Med 2012; 4: 130ra46.
-
(2012)
Sci Transl Med
, vol.4
-
-
Kannan, S.1
Dai, H.2
Navath, R.S.3
-
134
-
-
0033376651
-
Dendrimer-platinate: a novel approach to cancer chemotherapy
-
Malik N, Evagorou EG, Duncan R. Dendrimer-platinate: a novel approach to cancer chemotherapy. Anticancer Drugs 1999; 10: 767-76.
-
(1999)
Anticancer Drugs
, vol.10
, pp. 767-776
-
-
Malik, N.1
Evagorou, E.G.2
Duncan, R.3
-
135
-
-
84858060982
-
Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models
-
Kaminskas LM, McLeod VM, Kelly BD et al. Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumor models. Mol Pharm 2012; 9: 422-32.
-
(2012)
Mol Pharm
, vol.9
, pp. 422-432
-
-
Kaminskas, L.M.1
McLeod, V.M.2
Kelly, B.D.3
-
136
-
-
77952226982
-
PEGylated PAMAM dendrimers as a potential drug delivery carrier: in vitro and in vivo comparative evaluation of covalently conjugated drug and noncovalent drug inclusion complex
-
Jiang YY, Tang G-T, Zhang L-H, Kong S-Y, Zhu S-J, Pei Y-Y. PEGylated PAMAM dendrimers as a potential drug delivery carrier: in vitro and in vivo comparative evaluation of covalently conjugated drug and noncovalent drug inclusion complex. J Drug Target 2010; 18: 389-403.
-
(2010)
J Drug Target
, vol.18
, pp. 389-403
-
-
Jiang, Y.Y.1
Tang, G.-T.2
Zhang, L.-H.3
Kong, S.-Y.4
Zhu, S.-J.5
Pei, Y.-Y.6
-
137
-
-
80054981542
-
RGD-modified PEG-PAMAM-DOX conjugates: in vitro and in vivo studies for glioma
-
Zhang L, Zhu S, Qian L, Pei Y, Qiu Y, Jiang Y. RGD-modified PEG-PAMAM-DOX conjugates: in vitro and in vivo studies for glioma. Eur J Pharm Biopharm 2011; 79: 232-40.
-
(2011)
Eur J Pharm Biopharm
, vol.79
, pp. 232-240
-
-
Zhang, L.1
Zhu, S.2
Qian, L.3
Pei, Y.4
Qiu, Y.5
Jiang, Y.6
-
138
-
-
79959861668
-
The treatment of Glioblastoma Xenografts by surfactant conjugated dendritic nanoconjugates
-
Gajbhiye V, Jain NK. The treatment of Glioblastoma Xenografts by surfactant conjugated dendritic nanoconjugates. Biomaterials 2011; 32: 6213-25.
-
(2011)
Biomaterials
, vol.32
, pp. 6213-6225
-
-
Gajbhiye, V.1
Jain, N.K.2
-
139
-
-
84876512877
-
Pegylated dendrimer and its effect in fluorouracil loading and release for enhancing antitumor activity
-
Ly TU, Tran NQ, Hoang TKD, Phan KN, Truong HN, Nguyen CK. Pegylated dendrimer and its effect in fluorouracil loading and release for enhancing antitumor activity. J Biomed Nanotechnol 2013; 9: 213-20.
-
(2013)
J Biomed Nanotechnol
, vol.9
, pp. 213-220
-
-
Ly, T.U.1
Tran, N.Q.2
Hoang, T.K.D.3
Phan, K.N.4
Truong, H.N.5
Nguyen, C.K.6
-
140
-
-
56749185962
-
Folate and folate-PEG-PAMAM dendrimers: synthesis, characterization, and targeted anticancer drug deliery potential in tumor bearing mice
-
Singh P, Gupta U, Asthana A, Jain NK. Folate and folate-PEG-PAMAM dendrimers: synthesis, characterization, and targeted anticancer drug deliery potential in tumor bearing mice. Bioconjug Chem 2008; 19: 2239-52.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 2239-2252
-
-
Singh, P.1
Gupta, U.2
Asthana, A.3
Jain, N.K.4
-
141
-
-
70350055331
-
Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates
-
Fox ME, Guillaudeu S, Fréchet JMJ, Jerger K, Macaraeg N, Szoka FC. Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. Mol Pharm 2009; 6: 1562-672.
-
(2009)
Mol Pharm
, vol.6
, pp. 1562-1672
-
-
Fox, M.E.1
Guillaudeu, S.2
Fréchet, J.M.J.3
Jerger, K.4
Macaraeg, N.5
Szoka, F.C.6
-
142
-
-
0035181482
-
Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo-DNA complexed with dendrimers and/or avidin in mice1
-
Sato N, Kobayashi H, Saga T et al. Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo-DNA complexed with dendrimers and/or avidin in mice1. Clin Cancer Res 2001; 7: 3606-12.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3606-3612
-
-
Sato, N.1
Kobayashi, H.2
Saga, T.3
-
143
-
-
0037544228
-
Efficacy of dendrimer-mediated angiostatin and TIMP-2 gene delivery on inhibition of tumor growth and angiogenesis: in vitro and in vivo studies
-
Vincent L, Varet J, Pille J-Y et al. Efficacy of dendrimer-mediated angiostatin and TIMP-2 gene delivery on inhibition of tumor growth and angiogenesis: in vitro and in vivo studies. Int J Cancer 2003; 105: 419-29.
-
(2003)
Int J Cancer
, vol.105
, pp. 419-429
-
-
Vincent, L.1
Varet, J.2
Pille, J.-Y.3
-
144
-
-
77950341675
-
Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA
-
Koppu S, Oh YJ, Edrada-Ebel RA et al. Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. J Control Release 2010; 143: 215-21.
-
(2010)
J Control Release
, vol.143
, pp. 215-221
-
-
Koppu, S.1
Oh, Y.J.2
Edrada-Ebel, R.A.3
-
145
-
-
3542993234
-
Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation
-
Shaunak S, Thomas S, Gianasi E et al. Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nat Biotechnol 2004; 22: 977-84.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 977-984
-
-
Shaunak, S.1
Thomas, S.2
Gianasi, E.3
-
146
-
-
77954315628
-
Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers
-
Wang B, Navath RS, Menjoge AR et al. Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers. Int J Pharm 2010; 395: 298-308.
-
(2010)
Int J Pharm
, vol.395
, pp. 298-308
-
-
Wang, B.1
Navath, R.S.2
Menjoge, A.R.3
-
147
-
-
0036838275
-
Prevention of influenza pneumonitis by sialic acid conjugated dendritic polymers
-
Landers JJ, Cao Z, Lee I et al. Prevention of influenza pneumonitis by sialic acid conjugated dendritic polymers. J Infect Dis 2002; 186: 1222-30.
-
(2002)
J Infect Dis
, vol.186
, pp. 1222-1230
-
-
Landers, J.J.1
Cao, Z.2
Lee, I.3
-
148
-
-
33846115676
-
PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug
-
Kumar PV, Agashe H, Dutta T, Jain NK. PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug. Curr Drug Deliv 2007; 4: 11-9.
-
(2007)
Curr Drug Deliv
, vol.4
, pp. 11-19
-
-
Kumar, P.V.1
Agashe, H.2
Dutta, T.3
Jain, N.K.4
-
149
-
-
80052844387
-
®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans
-
®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans. PLoS One 2011; 6: e24095.
-
(2011)
PLoS One
, vol.6
, pp. e24095
-
-
Price, C.F.1
Tyssen, D.2
Sonza, S.3
-
150
-
-
82955237641
-
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiciently suppresses HIV-1 infection in humanized mice
-
Zhou J, Neff CP, Liu X et al. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiciently suppresses HIV-1 infection in humanized mice. Mol Ther 2011; 19: 2228-38.
-
(2011)
Mol Ther
, vol.19
, pp. 2228-2238
-
-
Zhou, J.1
Neff, C.P.2
Liu, X.3
-
151
-
-
0035105015
-
3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with reference to their pharmokinetic properties
-
Kobayashi H, Sato N, Hiraga A et al. 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with reference to their pharmokinetic properties. Magn Reson Med 2001; 45: 454-60.
-
(2001)
Magn Reson Med
, vol.45
, pp. 454-460
-
-
Kobayashi, H.1
Sato, N.2
Hiraga, A.3
-
152
-
-
0035145270
-
Comparison of the macromolecular MR contrast agents with ethylenediamine-core versus ammonia-core generation-6 polyamidoamine dendrimer
-
Kobayashi H, Sato N, Kawamoto S et al. Comparison of the macromolecular MR contrast agents with ethylenediamine-core versus ammonia-core generation-6 polyamidoamine dendrimer. Bioconjug Chem 2001; 12: 100-7.
-
(2001)
Bioconjug Chem
, vol.12
, pp. 100-107
-
-
Kobayashi, H.1
Sato, N.2
Kawamoto, S.3
-
153
-
-
0035190689
-
Pharmacokinetics and enhancement of macromolecular MR contrast agents with various sizes of polyamidoamine dendrimer cores
-
Sato N, Kobayashi H, Hiraga A et al. Pharmacokinetics and enhancement of macromolecular MR contrast agents with various sizes of polyamidoamine dendrimer cores. Magn Reson Med 2001; 46: 1169-73.
-
(2001)
Magn Reson Med
, vol.46
, pp. 1169-1173
-
-
Sato, N.1
Kobayashi, H.2
Hiraga, A.3
-
154
-
-
80053083875
-
Development and application of a multimodal contrast agent for SPECT/CT hybrid imaging
-
Criscione JM, Dobrucki LW, Papademetris X, Simons M, Sinusas AJ, Fahmy TA. Development and application of a multimodal contrast agent for SPECT/CT hybrid imaging. Bioconjug Chem 2011; 22: 1784-92.
-
(2011)
Bioconjug Chem
, vol.22
, pp. 1784-1792
-
-
Criscione, J.M.1
Dobrucki, L.W.2
Papademetris, X.3
Simons, M.4
Sinusas, A.J.5
Fahmy, T.A.6
-
155
-
-
84894468671
-
64Cu-labeled LyP-1-dendrimer for PET-CT imaging of atherosclerotic placque
-
64Cu-labeled LyP-1-dendrimer for PET-CT imaging of atherosclerotic placque. Bioconjug Chem 2014; 25: 231-9.
-
(2014)
Bioconjug Chem
, vol.25
, pp. 231-239
-
-
Seo, J.W.1
Baek, H.2
Mahakian, L.M.3
-
156
-
-
84879540484
-
Nanoparticle-based chemical exchange saturation transfer (CEST) agents
-
Castelli DD, Terreno E, Longo D, Aime S. Nanoparticle-based chemical exchange saturation transfer (CEST) agents. NMR Biomed 2013; 26: 839-49.
-
(2013)
NMR Biomed
, vol.26
, pp. 839-849
-
-
Castelli, D.D.1
Terreno, E.2
Longo, D.3
Aime, S.4
-
158
-
-
67651089633
-
Using two chemical exchange saturation transfer magnetic resonance imaging contrast agents for molecular imaging studies
-
Ali MM, Liu G, Shah T, Flask CA, Pagel MD. Using two chemical exchange saturation transfer magnetic resonance imaging contrast agents for molecular imaging studies. Acc Chem Res 2009; 42: 915-24.
-
(2009)
Acc Chem Res
, vol.42
, pp. 915-924
-
-
Ali, M.M.1
Liu, G.2
Shah, T.3
Flask, C.A.4
Pagel, M.D.5
-
159
-
-
84878531449
-
Solubility enhancement of non-steroidal anti-inflammatory drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers
-
Koc FE, Senel M. Solubility enhancement of non-steroidal anti-inflammatory drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers. Int J Pharm 2013; 451: 18-22.
-
(2013)
Int J Pharm
, vol.451
, pp. 18-22
-
-
Koc, F.E.1
Senel, M.2
-
160
-
-
84878664140
-
Click dendrimers as anti-inflammatory agents: with insights into their binding from molecular modeling studies
-
Neibert K, Gosein V, Sharma A et al. Click dendrimers as anti-inflammatory agents: with insights into their binding from molecular modeling studies. Mol Pharm 2013; 10: 2502-8.
-
(2013)
Mol Pharm
, vol.10
, pp. 2502-2508
-
-
Neibert, K.1
Gosein, V.2
Sharma, A.3
-
161
-
-
84896934276
-
Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest
-
Mishra MK, Beaty CA, Lesniak WG et al. Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest. ACS Nano 2014; 8: 2134-47.
-
(2014)
ACS Nano
, vol.8
, pp. 2134-2147
-
-
Mishra, M.K.1
Beaty, C.A.2
Lesniak, W.G.3
-
162
-
-
78650070100
-
Intrinsic targeting of inflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration
-
Dai H, Navath RS, Balakrishnan B et al. Intrinsic targeting of inflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration. Nanomedicine (Lond) 2010; 5: 1317-29.
-
(2010)
Nanomedicine (Lond)
, vol.5
, pp. 1317-1329
-
-
Dai, H.1
Navath, R.S.2
Balakrishnan, B.3
-
163
-
-
84872165093
-
In vivo distribution and toxicity of PAMAM dendrimers in the central nervous system depend on their surface chemistry
-
Albertazzi L, Gherardini L, Brondi M et al. In vivo distribution and toxicity of PAMAM dendrimers in the central nervous system depend on their surface chemistry. Mol Pharm 2013; 10: 249-60.
-
(2013)
Mol Pharm
, vol.10
, pp. 249-260
-
-
Albertazzi, L.1
Gherardini, L.2
Brondi, M.3
-
164
-
-
41649102800
-
Whither antibacterial drug discovery?
-
Projan SJ. Whither antibacterial drug discovery? Drug Discovery Today 2008; 13: 279-80.
-
(2008)
Drug Discovery Today
, vol.13
, pp. 279-280
-
-
Projan, S.J.1
-
166
-
-
0035989698
-
Interactions between dendrimer biocides and bacterial membranes
-
Chen CZ, Cooper SL. Interactions between dendrimer biocides and bacterial membranes. Biomaterials 2002; 23: 3359-68.
-
(2002)
Biomaterials
, vol.23
, pp. 3359-3368
-
-
Chen, C.Z.1
Cooper, S.L.2
-
167
-
-
78650316044
-
Biomedical applications of dendrimers: a tutorial
-
Mintzer MA, Grinstaff MW. Biomedical applications of dendrimers: a tutorial. Chem Soc Rev 2011; 40: 173-90.
-
(2011)
Chem Soc Rev
, vol.40
, pp. 173-190
-
-
Mintzer, M.A.1
Grinstaff, M.W.2
-
168
-
-
0002670007
-
Dendrimer - silver complexes and nanocomposites as antimicrobial agents
-
Balogh L, Swanson DR, Tomalia DA, Hagnauer GL, McManus AT. Dendrimer - silver complexes and nanocomposites as antimicrobial agents. Nano Lett 2001; 1: 18-21.
-
(2001)
Nano Lett
, vol.1
, pp. 18-21
-
-
Balogh, L.1
Swanson, D.R.2
Tomalia, D.A.3
Hagnauer, G.L.4
McManus, A.T.5
-
169
-
-
84858013352
-
Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases
-
Mintzer MA, Dane EL, O'Toole GA, Grinstaff MW. Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm 2012; 9: 342-54.
-
(2012)
Mol Pharm
, vol.9
, pp. 342-354
-
-
Mintzer, M.A.1
Dane, E.L.2
O'Toole, G.A.3
Grinstaff, M.W.4
-
171
-
-
84872865923
-
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface
-
Choi SK, Myc A, Silpe JE et al. Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface. ACS Nano 2013; 7: 214-28.
-
(2013)
ACS Nano
, vol.7
, pp. 214-228
-
-
Choi, S.K.1
Myc, A.2
Silpe, J.E.3
-
172
-
-
84865764962
-
Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers
-
Teo I, Toms SM, Marteyn B et al. Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers. EMBO Mol Med 2012; 4: 866-81.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 866-881
-
-
Teo, I.1
Toms, S.M.2
Marteyn, B.3
-
173
-
-
33644889388
-
PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate
-
Bhadra D, Bhadra S, Jain NK. PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate. Pharm Res 2006; 23: 623-33.
-
(2006)
Pharm Res
, vol.23
, pp. 623-633
-
-
Bhadra, D.1
Bhadra, S.2
Jain, N.K.3
-
174
-
-
10744228936
-
Evaluations of unformulated and formulated dendrimer-based microbicide candidates in mouse and guinea pig models of genital herpes
-
Bernstein DI, Stanberry LR, Sacks S et al. Evaluations of unformulated and formulated dendrimer-based microbicide candidates in mouse and guinea pig models of genital herpes. Antimicrob Agents Chemother 2003; 47: 3784-8.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3784-3788
-
-
Bernstein, D.I.1
Stanberry, L.R.2
Sacks, S.3
-
175
-
-
16444385352
-
SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques
-
Jiang YH, Emau P, Cairns JS et al. SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques. AIDS Res Hum Retroviruses 2005; 21: 207-13.
-
(2005)
AIDS Res Hum Retroviruses
, vol.21
, pp. 207-213
-
-
Jiang, Y.H.1
Emau, P.2
Cairns, J.S.3
-
177
-
-
84872529442
-
Influence of surface groups on poly(propylene imine) dendrimers antiprion activity
-
McCarthy JM, Moreno BR, Filippini D et al. Influence of surface groups on poly(propylene imine) dendrimers antiprion activity. Biomacromolecules 2013; 14: 27-37.
-
(2013)
Biomacromolecules
, vol.14
, pp. 27-37
-
-
McCarthy, J.M.1
Moreno, B.R.2
Filippini, D.3
-
179
-
-
84879813285
-
Nanomedicine for prion disease treatment: new insights into the role of dendrimers
-
McCarthy JM, Appelhans D, Tatzelt J, Rogers MS. Nanomedicine for prion disease treatment: new insights into the role of dendrimers. Prion 2013; 7: 198-202.
-
(2013)
Prion
, vol.7
, pp. 198-202
-
-
McCarthy, J.M.1
Appelhans, D.2
Tatzelt, J.3
Rogers, M.S.4
-
180
-
-
72149092999
-
Interactions between dendrimers and heparin and their implications for the anti-prion activity of dendrimers
-
Klajnert B, Cangiotti M, Calici S et al. Interactions between dendrimers and heparin and their implications for the anti-prion activity of dendrimers. New J Chem 2009; 33: 1087-93.
-
(2009)
New J Chem
, vol.33
, pp. 1087-1093
-
-
Klajnert, B.1
Cangiotti, M.2
Calici, S.3
-
181
-
-
84856735496
-
Glycodendrimers as functional antigens and antitumor vaccines
-
Shiao TC, Roy R. Glycodendrimers as functional antigens and antitumor vaccines. New J Chem 2012; 36: 324-39.
-
(2012)
New J Chem
, vol.36
, pp. 324-339
-
-
Shiao, T.C.1
Roy, R.2
-
182
-
-
84897504262
-
Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy
-
Kaminskas LM, McLeod VM, Ryan GM et al. Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy. J Control Release 2014; 183: 18-26.
-
(2014)
J Control Release
, vol.183
, pp. 18-26
-
-
Kaminskas, L.M.1
McLeod, V.M.2
Ryan, G.M.3
-
183
-
-
59649120675
-
Dendrimers in oncology: an expanding horizon
-
Tekade RK, Kumar PV, Jain NK. Dendrimers in oncology: an expanding horizon. Chem Rev 2009; 109: 49-87.
-
(2009)
Chem Rev
, vol.109
, pp. 49-87
-
-
Tekade, R.K.1
Kumar, P.V.2
Jain, N.K.3
-
186
-
-
77955272031
-
Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery
-
Navarro G, Maiwald G, Haase R et al. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery. J Control Release 2010; 146: 99-105.
-
(2010)
J Control Release
, vol.146
, pp. 99-105
-
-
Navarro, G.1
Maiwald, G.2
Haase, R.3
-
187
-
-
84891926803
-
RNA-mediated gene activation
-
Jiao AL, Slack FJ. RNA-mediated gene activation. Epigenetics 2014; 9: 1-10.
-
(2014)
Epigenetics
, vol.9
, pp. 1-10
-
-
Jiao, A.L.1
Slack, F.J.2
-
189
-
-
34948840023
-
Designing hydrogel adhesives for corneal wound repair
-
Grinstaff MW. Designing hydrogel adhesives for corneal wound repair. Biomaterials 2007; 28: 5205-14.
-
(2007)
Biomaterials
, vol.28
, pp. 5205-5214
-
-
Grinstaff, M.W.1
-
190
-
-
65249106054
-
Compression of sutures and dendritic polymer adhesitves for cornial laceration repair in an in vivo chicken model
-
Berdahl JP, Johnson CS, Proia AD, Grinstaff MW, Kim T. Compression of sutures and dendritic polymer adhesitves for cornial laceration repair in an in vivo chicken model. Arch Ophthalmol 2009; 127: 442-7.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 442-447
-
-
Berdahl, J.P.1
Johnson, C.S.2
Proia, A.D.3
Grinstaff, M.W.4
Kim, T.5
-
191
-
-
65249114842
-
In vitro sealing of clear corneal cataract incisions with a novel biodendrimer adhesive
-
Johnson CS, Wathier M, Grinstaff MW, Kim T. In vitro sealing of clear corneal cataract incisions with a novel biodendrimer adhesive. Arch Ophthalmol 2009; 127: 430-4.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 430-434
-
-
Johnson, C.S.1
Wathier, M.2
Grinstaff, M.W.3
Kim, T.4
-
192
-
-
2942585621
-
New dendritic adhesives for sutureless ophthalmic surgical procedures
-
Velazquez AJ, Carnahan MA, Kristinsson J, Stinnett S, Grinstaff MW, Kim T. New dendritic adhesives for sutureless ophthalmic surgical procedures. Arch Ophthalmol 2004; 122: 867-70.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 867-870
-
-
Velazquez, A.J.1
Carnahan, M.A.2
Kristinsson, J.3
Stinnett, S.4
Grinstaff, M.W.5
Kim, T.6
-
193
-
-
68549123611
-
Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma
-
Kang SJ, Durairaj C, Kompella UB, O'Brien JM, Grossniklaus HE. Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma. Arch Ophthalmol 2009; 127: 1043-7.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 1043-1047
-
-
Kang, S.J.1
Durairaj, C.2
Kompella, U.B.3
O'Brien, J.M.4
Grossniklaus, H.E.5
-
194
-
-
84899085765
-
Dendrimers for gene delivery - a potential approach for ocular therapy?
-
Chaplot SP, Rupenthal ID. Dendrimers for gene delivery - a potential approach for ocular therapy? J Pharm Pharmacol 2013; 66: 542-56.
-
(2013)
J Pharm Pharmacol
, vol.66
, pp. 542-556
-
-
Chaplot, S.P.1
Rupenthal, I.D.2
-
195
-
-
77956183767
-
Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies - a review
-
Oliveira JM, Salgado AJ, Sousa N, Mano JF. Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies - a review. Prog Polym Sci 2010; 35: 1163-94.
-
(2010)
Prog Polym Sci
, vol.35
, pp. 1163-1194
-
-
Oliveira, J.M.1
Salgado, A.J.2
Sousa, N.3
Mano, J.F.4
-
196
-
-
84866656642
-
Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration
-
Yang H, Tyagi P, Kadam RS, Holden CA, Kompella UB. Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. ACS Nano 2012; 6: 7595-606.
-
(2012)
ACS Nano
, vol.6
, pp. 7595-7606
-
-
Yang, H.1
Tyagi, P.2
Kadam, R.S.3
Holden, C.A.4
Kompella, U.B.5
-
197
-
-
84875021801
-
Dendrimer nanoparticles for ocular drug delivery
-
Kambhampati SP, Kannan RM. Dendrimer nanoparticles for ocular drug delivery. J Ocul Pharmacol Ther 2013; 29: 151-65.
-
(2013)
J Ocul Pharmacol Ther
, vol.29
, pp. 151-165
-
-
Kambhampati, S.P.1
Kannan, R.M.2
-
198
-
-
84893828474
-
Dendrimeric systems and their applications in ocular drug delivery
-
Yavuz B, Pehlivan SB, Unlu N. Dendrimeric systems and their applications in ocular drug delivery. Scientific World Journal 2013; 2013: 1-13.
-
(2013)
Scientific World Journal
, vol.2013
, pp. 1-13
-
-
Yavuz, B.1
Pehlivan, S.B.2
Unlu, N.3
-
200
-
-
85057430652
-
-
eds. New York, NY: Informa Healthcare USA.
-
Monteiro-Riviere NA, Tran CL, eds. Nanotoxicology: Characterization, Dosing, and Health Effects. New York, NY: Informa Healthcare USA. 2007.
-
(2007)
Nanotoxicology: Characterization, Dosing, and Health Effects
-
-
Monteiro-Riviere, N.A.1
Tran, C.L.2
-
201
-
-
34247953814
-
More is different
-
Anderson PW. More is different. Science 1972; 177: 393-6.
-
(1972)
Science
, vol.177
, pp. 393-396
-
-
Anderson, P.W.1
-
203
-
-
80052280058
-
Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties
-
Kaminskas LM, Boyd BJ, Porter CJH. Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties. Nanomedicine (Lond) 2011; 6: 1063-84.
-
(2011)
Nanomedicine (Lond)
, vol.6
, pp. 1063-1084
-
-
Kaminskas, L.M.1
Boyd, B.J.2
Porter, C.J.H.3
-
204
-
-
84875357552
-
Nanomateral toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening
-
Nel A, Xia T, Meng H et al. Nanomateral toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Acc Chem Res 2013; 46: 607-21.
-
(2013)
Acc Chem Res
, vol.46
, pp. 607-621
-
-
Nel, A.1
Xia, T.2
Meng, H.3
-
205
-
-
84864425311
-
A quantized building block concept leading to a new nano-periodic system
-
New York, NY: Cambridge University Press
-
Tomalia DA, Christensen JB, Boas U. A quantized building block concept leading to a new nano-periodic system. In: Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future. New York, NY: Cambridge University Press, 2012; 293-377.
-
(2012)
Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future
, pp. 293-377
-
-
Tomalia, D.A.1
Christensen, J.B.2
Boas, U.3
-
206
-
-
0035191513
-
Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generatioin of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents
-
Kobayashi H, Kawamoto S, Saga T et al. Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generatioin of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents. J Magn Reson Imaging 2001; 14: 705-13.
-
(2001)
J Magn Reson Imaging
, vol.14
, pp. 705-713
-
-
Kobayashi, H.1
Kawamoto, S.2
Saga, T.3
-
207
-
-
84911989928
-
Toxicology of dendrimers and dendrons
-
New York, NY: Cambridge University Press
-
Tomalia DA, Christensen JB, Boas U. Toxicology of dendrimers and dendrons. In: Dendrimers, dendrons, and dendritic polymers: discovery, applications and the future. New York, NY: Cambridge University Press, 2012; 255-75.
-
(2012)
Dendrimers, dendrons, and dendritic polymers: discovery, applications and the future
, pp. 255-275
-
-
Tomalia, D.A.1
Christensen, J.B.2
Boas, U.3
-
208
-
-
84865505095
-
Dendritic nanoparticles: the next generation of nanocarriers?
-
Pearson RM, Sunoqrot S, Hsu H-J, Bae JW, Hong S. Dendritic nanoparticles: the next generation of nanocarriers? Ther Deliv 2012; 3: 941-59.
-
(2012)
Ther Deliv
, vol.3
, pp. 941-959
-
-
Pearson, R.M.1
Sunoqrot, S.2
Hsu, H.-J.3
Bae, J.W.4
Hong, S.5
-
209
-
-
55949126429
-
Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats
-
Longmire M, Choyke PL, Kobayashi H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine 2008; 3: 703-17.
-
(2008)
Nanomedicine
, vol.3
, pp. 703-717
-
-
Longmire, M.1
Choyke, P.L.2
Kobayashi, H.3
-
210
-
-
0034005436
-
Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125 l-labelled polyamidoamine dendrimers in vivo
-
Malik N, Wiwattanapatapee R, Klopsch R et al. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125 l-labelled polyamidoamine dendrimers in vivo. J Control Release 2000; 65: 133-48.
-
(2000)
J Control Release
, vol.65
, pp. 133-148
-
-
Malik, N.1
Wiwattanapatapee, R.2
Klopsch, R.3
-
211
-
-
84864425311
-
Nanomedical and advanced materials
-
New York, NY: Cambridge University Press
-
Tomalia DA, Christensen JB, Boas U. Nanomedical and advanced materials. In: Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future. New York, NY: Cambridge University Press, 2012; 187-254.
-
(2012)
Dendrimers, Dendrons, and Dendritic Polymers: Discovery, Applications and the Future
, pp. 187-254
-
-
Tomalia, D.A.1
Christensen, J.B.2
Boas, U.3
-
212
-
-
84870463672
-
Cationic PAMAM dendrimers aggressively initiate blood clot formation
-
Jones CF, Campbell RA, Brooks BD, Ghandehari H, Grainger DW. Cationic PAMAM dendrimers aggressively initiate blood clot formation. ACS Nano 2012; 6: 9900-10.
-
(2012)
ACS Nano
, vol.6
, pp. 9900-9910
-
-
Jones, C.F.1
Campbell, R.A.2
Brooks, B.D.3
Ghandehari, H.4
Grainger, D.W.5
-
213
-
-
84862001474
-
Cationic PAMAM dendrimers disrupt key platelet functions
-
Jones CF, Campbell RA, Franks Z et al. Cationic PAMAM dendrimers disrupt key platelet functions. Mol Pharm 2012; 9: 1599-611.
-
(2012)
Mol Pharm
, vol.9
, pp. 1599-1611
-
-
Jones, C.F.1
Campbell, R.A.2
Franks, Z.3
-
214
-
-
84867528048
-
Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles
-
Greish K, Thiagarajan G, Herd H et al. Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles. Nanotoxicology 2010; 6: 713-23.
-
(2010)
Nanotoxicology
, vol.6
, pp. 713-723
-
-
Greish, K.1
Thiagarajan, G.2
Herd, H.3
-
215
-
-
68049107455
-
Synthesis, radiolabeling, and bio-imaging of high-generation polyester dendrimers
-
Parrott MC, Benhabbour SR, Saab C et al. Synthesis, radiolabeling, and bio-imaging of high-generation polyester dendrimers. J Am Chem Soc 2009; 131: 2906-16.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 2906-2916
-
-
Parrott, M.C.1
Benhabbour, S.R.2
Saab, C.3
-
216
-
-
70449526181
-
Influence of dendrimer generation and polyethylene glycol length on the biodistribution of PEGylated dendrimers
-
Kojima C, Regino CAS, Umeda Y, Kobayashi H, Kono K. Influence of dendrimer generation and polyethylene glycol length on the biodistribution of PEGylated dendrimers. Int J Pharm 2010; 383: 293-6.
-
(2010)
Int J Pharm
, vol.383
, pp. 293-296
-
-
Kojima, C.1
Regino, C.A.S.2
Umeda, Y.3
Kobayashi, H.4
Kono, K.5
-
217
-
-
80955130278
-
Dendrimer-based MRI contrast agents: the effects of PEGylation on relaxivity and pharmacokinetics
-
Kojima C, Turkbey B, Ogawa M et al. Dendrimer-based MRI contrast agents: the effects of PEGylation on relaxivity and pharmacokinetics. Nanomed Nanotechnol Biol Med 2011; 7: 1001-8.
-
(2011)
Nanomed Nanotechnol Biol Med
, vol.7
, pp. 1001-1008
-
-
Kojima, C.1
Turkbey, B.2
Ogawa, M.3
-
218
-
-
84887407466
-
Implementation of alternative test strategies for the safety assessment of engineered nanomaterials
-
Nel AE. Implementation of alternative test strategies for the safety assessment of engineered nanomaterials. J Int Med 2013; 274: 561-77.
-
(2013)
J Int Med
, vol.274
, pp. 561-577
-
-
Nel, A.E.1
-
219
-
-
31944451232
-
Toxic potential of materials at the nanolevel
-
Nel A, Xia T, Madler L, Li N. Toxic potential of materials at the nanolevel. Science 2006; 311: 622-7.
-
(2006)
Science
, vol.311
, pp. 622-627
-
-
Nel, A.1
Xia, T.2
Madler, L.3
Li, N.4
-
220
-
-
39349118236
-
Toxicology. Transforming environmental health protection
-
Collins FS, Gray GM, Butcher JR. Toxicology. Transforming environmental health protection. Science 2008; 319: 906-7.
-
(2008)
Science
, vol.319
, pp. 906-907
-
-
Collins, F.S.1
Gray, G.M.2
Butcher, J.R.3
-
221
-
-
67650445156
-
Toxicology for the twenty-first century
-
Hartung T. Toxicology for the twenty-first century. Nature 2009; 460: 208-12.
-
(2009)
Nature
, vol.460
, pp. 208-212
-
-
Hartung, T.1
-
222
-
-
71949117632
-
Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology
-
Oberdorster G. Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology. J Intern Med 2010; 267: 89-105.
-
(2010)
J Intern Med
, vol.267
, pp. 89-105
-
-
Oberdorster, G.1
-
223
-
-
70349144397
-
Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs)
-
Jacobson KA. Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs). Bioconjug Chem 2009; 20: 1816-35.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 1816-1835
-
-
Jacobson, K.A.1
-
224
-
-
84881222126
-
Dendrimers terminated with dichlorotrizine groups provide a route to compositional diversity
-
Patra S, Kozura B, Huang AY-T et al. Dendrimers terminated with dichlorotrizine groups provide a route to compositional diversity. Org Lett 2013; 15: 3808-11.
-
(2013)
Org Lett
, vol.15
, pp. 3808-3811
-
-
Patra, S.1
Kozura, B.2
Huang, A.-T.3
-
225
-
-
84887407783
-
Nanosafety: towards safer design of nanomedicines
-
Fadeel B. Nanosafety: towards safer design of nanomedicines. J Intern Med 2013; 274: 578-80.
-
(2013)
J Intern Med
, vol.274
, pp. 578-580
-
-
Fadeel, B.1
-
227
-
-
81855218204
-
Reshaping the future of nanopharmaceuticals: ad Iudicium
-
Moghimi SM, Peer D, Langer R. Reshaping the future of nanopharmaceuticals: ad Iudicium. ACS Nano 2011; 5: 8454-8.
-
(2011)
ACS Nano
, vol.5
, pp. 8454-8458
-
-
Moghimi, S.M.1
Peer, D.2
Langer, R.3
|