Principles of nanoparticle design for overcoming biological barriers to drug delivery

Nature Biotechnology

Volumn 33, Issue 9, 2015, Pages 941-951

  Blanco, Elvin ^a   Shen, Haifa ^a,b   Ferrari, Mauro ^a,b  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLES;

BIOLOGICAL BARRIER; DISEASE PROCESS; DRUG TRANSPORT; INNOVATIVE DESIGN; INTRAVENOUS ADMINISTRATION; NANOCARRIERS; RESEARCH EFFORTS; SITE-SPECIFIC;

DESIGN;

CREMOPHOR; NANOCARRIER; BIOMATERIAL; NANOCAPSULE;

BLOOD RHEOLOGY; CELL COMPARTMENTALIZATION; CELL MEMBRANE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG TRANSPORT; ENDOCYTOSIS; ENDOSOME; HEMODYNAMICS; HUMAN; INTERNALIZATION; INTRAVASCULAR DRUG ADMINISTRATION; LIPID BILAYER; MONONUCLEAR PHAGOCYTE; MULTIDRUG RESISTANCE; NANOMEDICINE; NONHUMAN; OPSONIZATION; PARTICLE SIZE; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; REVIEW; SURFACE CHARGE; TISSUE PRESSURE; CHEMISTRY; DRUG DESIGN; PROCEDURES; SYNTHESIS; ULTRASTRUCTURE;

BIOCOMPATIBLE MATERIALS; DRUG COMPOUNDING; DRUG DESIGN; NANOCAPSULES; NANOMEDICINE;

EID: 84941066997     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3330     Document Type: Review

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