-
1
-
-
0019463519
-
Targeting of drugs: Implications in medicine
-
Gregoriadis G. Targeting of drugs: implications in medicine. Lancet 1981; II: 241-6
-
(1981)
Lancet
, vol.2
, pp. 241-246
-
-
Gregoriadis, G.1
-
2
-
-
0016612425
-
The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs
-
Juliano R, Stamp D. The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs. Biochem Biophys Res Commun 1975; 63: 651-8
-
(1975)
Biochem Biophys Res Commun
, vol.63
, pp. 651-658
-
-
Juliano, R.1
Stamp, D.2
-
3
-
-
0020049344
-
Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery
-
Poste G, Bucana C, Raz A, et al. Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery. Cancer Res 1982; 42: 1412-22
-
(1982)
Cancer Res
, vol.42
, pp. 1412-1422
-
-
Poste, G.1
Bucana, C.2
Raz, A.3
-
4
-
-
0023649923
-
Uptake of small liposomes by non-reticuloendothelial tissues
-
Hwang KJ, Padki MM, Chow DD, et al. Uptake of small liposomes by non-reticuloendothelial tissues. Biochim Biophys Acta 1987; 901: 88-96
-
(1987)
Biochim Biophys Acta
, vol.901
, pp. 88-96
-
-
Hwang, K.J.1
Padki, M.M.2
Chow, D.D.3
-
5
-
-
0842279809
-
Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors
-
Gabizon A, Papahadjopoulos D. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors. Proc Natl Acad Sci U S A 1988; 85: 6949-53
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6949-6953
-
-
Gabizon, A.1
Papahadjopoulos, D.2
-
6
-
-
0030778570
-
Pegylated liposomal doxorubicin: Scientific rationale and preclinical pharmacology
-
Martin FJ. Pegylated liposomal doxorubicin: scientific rationale and preclinical pharmacology. Oncology 1997; 11: 11-32
-
(1997)
Oncology
, vol.11
, pp. 11-32
-
-
Martin, F.J.1
-
7
-
-
0032580445
-
Development of liposomal anthracyclines: From basics to clinical applications
-
Gabizon A, Goren D, Cohen R, et al. Development of liposomal anthracyclines: from basics to clinical applications. J Control Release 1998; 53: 275-9
-
(1998)
J Control Release
, vol.53
, pp. 275-279
-
-
Gabizon, A.1
Goren, D.2
Cohen, R.3
-
8
-
-
0028920270
-
Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin
-
Gill PS, Espina BM, Muggia F, et al. Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin. J Clin Oncol 1995; 13: 996-1003
-
(1995)
J Clin Oncol
, vol.13
, pp. 996-1003
-
-
Gill, P.S.1
Espina, B.M.2
Muggia, F.3
-
9
-
-
0032974761
-
Phase I study of liposomal vincristine
-
Gelmon KA, Tolcher A, Diab AR, et al. Phase I study of liposomal vincristine. J Clin Oncol 1999; 17: 697-705
-
(1999)
J Clin Oncol
, vol.17
, pp. 697-705
-
-
Gelmon, K.A.1
Tolcher, A.2
Diab, A.R.3
-
10
-
-
0035005359
-
Pegylated liposomal doxorubicin: Metamorphosis of an old drug into a new form of chemotherapy
-
Gabizon AA. Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy. Cancer Invest 2001; 19: 424-36
-
(2001)
Cancer Invest
, vol.19
, pp. 424-436
-
-
Gabizon, A.A.1
-
12
-
-
0002985635
-
Polyethylene glycol-lipid conjugates
-
Lasic D, Martin F, editors. Boca Raton: CRC Press
-
Zalipsky S. Polyethylene glycol-lipid conjugates. In: Lasic D, Martin F, editors. Stealth liposomes. Boca Raton: CRC Press, 1995: 93-102
-
(1995)
Stealth Liposomes
, pp. 93-102
-
-
Zalipsky, S.1
-
14
-
-
0035085192
-
Liposome application: Problems and prospects
-
Barenholz Y. Liposome application: problems and prospects. Curr Opin Colloid Interface Sci 2001; 6: 66-77
-
(2001)
Curr Opin Colloid Interface Sci
, vol.6
, pp. 66-77
-
-
Barenholz, Y.1
-
15
-
-
0030886615
-
Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles
-
Cullis PR, Hope MJ, Bally MB, et al. Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles. Biochim Biophys Acta 1997; 1331: 187-211
-
(1997)
Biochim Biophys Acta
, vol.1331
, pp. 187-211
-
-
Cullis, P.R.1
Hope, M.J.2
Bally, M.B.3
-
16
-
-
0343923453
-
Long-circulating liposomes for drug delivery in cancer therapy: A review of biodistribution studies in tumor-beating animals
-
Gabizon A, Goren D, Horowitz AT, et al. Long-circulating liposomes for drug delivery in cancer therapy: a review of biodistribution studies in tumor-beating animals. Adv Drug Deliv Rev 1997; 24: 337-44
-
(1997)
Adv Drug Deliv Rev
, vol.24
, pp. 337-344
-
-
Gabizon, A.1
Goren, D.2
Horowitz, A.T.3
-
17
-
-
0003377686
-
Reduced cardiac toxicity and comparable efficacy in a phase III trial of pegylated lipsomal doxorubicin (Caelyx/Doxil) vs doxorubicin for first-line treatment of metastatic breast cancer
-
Wigler N, Inbar M, O'Brien M, et al. Reduced cardiac toxicity and comparable efficacy in a phase III trial of pegylated lipsomal doxorubicin (Caelyx/Doxil) vs doxorubicin for first-line treatment of metastatic breast cancer [abstract]. Proc Am Soc Clin Oncol (ASCO) 2002; 177
-
(2002)
Proc Am Soc Clin Oncol (ASCO)
, pp. 177
-
-
Wigler, N.1
Inbar, M.2
O'Brien, M.3
-
18
-
-
0035286282
-
Liposomal encapsulated anthracyclines: New therapeutic horizons
-
Muggia FM. Liposomal encapsulated anthracyclines: new therapeutic horizons. Curr Oncol Rep 2001; 3: 156-62
-
(2001)
Curr Oncol Rep
, vol.3
, pp. 156-162
-
-
Muggia, F.M.1
-
19
-
-
0036402578
-
Polyethylene glycol-liposomal doxorubicin: A review of its use in the management of solid and haematological malignancies and AIDS related Kaposi's sarcoma
-
Sharpe M, Easthope SE, Keating GM, et al. Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS related Kaposi's sarcoma. Drugs 2002; 62: 2089-126
-
(2002)
Drugs
, vol.62
, pp. 2089-2126
-
-
Sharpe, M.1
Easthope, S.E.2
Keating, G.M.3
-
20
-
-
0029765442
-
Pharmacological-toxicological expert report. CAELYX. (Stealth liposomal doxorubicin HCl)
-
Working PK, Dayan AD. Pharmacological-toxicological expert report. CAELYX. (Stealth liposomal doxorubicin HCl). Hum Exp Toxicol 1996; 15: 751-85
-
(1996)
Hum Exp Toxicol
, vol.15
, pp. 751-785
-
-
Working, P.K.1
Dayan, A.D.2
-
21
-
-
0032516078
-
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
-
Hobbs SK, Monsky WL, Yuan F, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci U S A 1998; 95: 4607-12
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4607-4612
-
-
Hobbs, S.K.1
Monsky, W.L.2
Yuan, F.3
-
22
-
-
0033839080
-
Openings between defective endothelial cells explain tumor vessel leakiness
-
Hashizume H, Baluk P, Morikawa S, et al. Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol 2000; 156: 1363-80
-
(2000)
Am J Pathol
, vol.156
, pp. 1363-1380
-
-
Hashizume, H.1
Baluk, P.2
Morikawa, S.3
-
23
-
-
0029150245
-
Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
-
Yuan F, Dellian M, Fukumura D, et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res 1995; 55: 3752-6
-
(1995)
Cancer Res
, vol.55
, pp. 3752-3756
-
-
Yuan, F.1
Dellian, M.2
Fukumura, D.3
-
24
-
-
0038466968
-
-
Glick D, editor. New York: Wiley
-
Lichtenberg D, Barenholz Y. Liposomes: preparation, characterization, and preservation. Vol 33. Glick D, editor. New York: Wiley, 1988
-
(1988)
Liposomes: Preparation, Characterization, and Preservation
, vol.33
-
-
Lichtenberg, D.1
Barenholz, Y.2
-
25
-
-
0034955555
-
DRV liposomal bupivacaine: Preparation, characterization, and in vivo evaluation in mice
-
Grant GJ, Barenholz Y, Piskoun B, et al. DRV liposomal bupivacaine: preparation, characterization, and in vivo evaluation in mice. Pharm Res 2001; 18: 336-43
-
(2001)
Pharm Res
, vol.18
, pp. 336-343
-
-
Grant, G.J.1
Barenholz, Y.2
Piskoun, B.3
-
26
-
-
0026453662
-
Gelation of liposome interior: A novel method for drug encapsulation
-
Lasic DD, Frederik PM, Stuart MC, et al. Gelation of liposome interior: a novel method for drug encapsulation. FEBS Lett 1992; 312: 255-8
-
(1992)
FEBS Lett
, vol.312
, pp. 255-258
-
-
Lasic, D.D.1
Frederik, P.M.2
Stuart, M.C.3
-
27
-
-
0028886643
-
Transmembrane gradient driven phase transitions within vesicles: Lessons for drug delivery
-
Lasic DD, Ceh B, Stuart MC, et al. Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery. Biochim Biophys Acta 1995; 1239: 145-56
-
(1995)
Biochim Biophys Acta
, vol.1239
, pp. 145-156
-
-
Lasic, D.D.1
Ceh, B.2
Stuart, M.C.3
-
28
-
-
0027514941
-
Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
-
Haran G, Cohen R, Bar LK, et al. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta 1993; 1151: 201-15
-
(1993)
Biochim Biophys Acta
, vol.1151
, pp. 201-215
-
-
Haran, G.1
Cohen, R.2
Bar, L.K.3
-
29
-
-
0028324117
-
Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes
-
Bolotin EM, Cohen R, Bar LK, et al. Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes. J Liposome Res 1994; 4: 455-79
-
(1994)
J Liposome Res
, vol.4
, pp. 455-479
-
-
Bolotin, E.M.1
Cohen, R.2
Bar, L.K.3
-
30
-
-
0026672406
-
In vitro cytotoxicity of liposome-encapsulated doxorubicin: Dependence on liposome composition and drug release
-
Horowitz AT, Barenholz Y, Gabizon AA. In vitro cytotoxicity of liposome-encapsulated doxorubicin: dependence on liposome composition and drug release. Biochim Biophys Acta 1992; 1109: 203-9
-
(1992)
Biochim Biophys Acta
, vol.1109
, pp. 203-209
-
-
Horowitz, A.T.1
Barenholz, Y.2
Gabizon, A.A.3
-
31
-
-
0029360317
-
Liposome circulation time and tumor targeting: Implications for cancer chemotherapy
-
Gabizon AA. Liposome circulation time and tumor targeting: implications for cancer chemotherapy. Adv Drug Deliv Rev 1995; 16: 285-94
-
(1995)
Adv Drug Deliv Rev
, vol.16
, pp. 285-294
-
-
Gabizon, A.A.1
-
32
-
-
0033400567
-
Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models
-
Bandak S, Goren D, Horowitz A, et al. Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models. Anticancer Drugs 1999; 10: 911-20
-
(1999)
Anticancer Drugs
, vol.10
, pp. 911-920
-
-
Bandak, S.1
Goren, D.2
Horowitz, A.3
-
33
-
-
0029585915
-
Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: Biodistribution and therapeutic efficacy
-
Siegal T, Horowitz A, Gabizon A. Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. J Neurosurg 1995; 83: 1029-37
-
(1995)
J Neurosurg
, vol.83
, pp. 1029-1037
-
-
Siegal, T.1
Horowitz, A.2
Gabizon, A.3
-
34
-
-
0027162899
-
Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: Pharmacokinetic studies in rodents and dogs
-
Gabizon AA, Barenholz Y, Bialer M. Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: pharmacokinetic studies in rodents and dogs. Pharm Res 1993; 10: 703-8
-
(1993)
Pharm Res
, vol.10
, pp. 703-708
-
-
Gabizon, A.A.1
Barenholz, Y.2
Bialer, M.3
-
35
-
-
0032958460
-
Relationship of dose intensity to the induction of palmar-plantar erythrodysesthia by pegylated liposomal doxorubicin in dogs
-
Amantea M, Newman MS, Sullivan TM, et al. Relationship of dose intensity to the induction of palmar-plantar erythrodysesthia by pegylated liposomal doxorubicin in dogs. Hum Exp Toxicol 1999; 18: 17-26
-
(1999)
Hum Exp Toxicol
, vol.18
, pp. 17-26
-
-
Amantea, M.1
Newman, M.S.2
Sullivan, T.M.3
-
36
-
-
0025789143
-
Pharmacokinetics of stealth versus conventional liposomes: Effect of dose
-
Allen TM, Hansen C. Pharmacokinetics of stealth versus conventional liposomes: effect of dose. Biochim Biophys Acta 1991; 1068: 133-41
-
(1991)
Biochim Biophys Acta
, vol.1068
, pp. 133-141
-
-
Allen, T.M.1
Hansen, C.2
-
37
-
-
0036875746
-
Dose dependency of pharmacokinetics and therapeutic efficacy of pegylated liposomal doxorubicin (DOXIL) in murine models
-
Gabizon A, Tzemach D, Mak L, et al. Dose dependency of pharmacokinetics and therapeutic efficacy of pegylated liposomal doxorubicin (DOXIL) in murine models. J Drug Target 2002; 10: 539-48
-
(2002)
J Drug Target
, vol.10
, pp. 539-548
-
-
Gabizon, A.1
Tzemach, D.2
Mak, L.3
-
38
-
-
0027133225
-
Preclinical studies with doxorubicin encapsulated in polyethyleneglycol-coated liposomes
-
Gabizon AA, Pappo O, Goren D, et al. Preclinical studies with doxorubicin encapsulated in polyethyleneglycol-coated liposomes. J Liposome Res 1993; 3: 517-28
-
(1993)
J Liposome Res
, vol.3
, pp. 517-528
-
-
Gabizon, A.A.1
Pappo, O.2
Goren, D.3
-
39
-
-
0000058786
-
Clinical pharmacokinetics of anthracycline antibiotics
-
Ames MM, Powis G, Kovach JS, editors. Amsterdam: Elsevier
-
Riggs Jr ER, Bachur R. Clinical pharmacokinetics of anthracycline antibiotics. In: Ames MM, Powis G, Kovach JS, editors. Pharmacokinetics of anticancer agents in humans. Amsterdam: Elsevier, 1983: 229-278
-
(1983)
Pharmacokinetics of Anticancer Agents in Humans
, pp. 229-278
-
-
Riggs E.R., Jr.1
Bachur, R.2
-
40
-
-
0026352832
-
Sterically stabilized liposomes: Improvements in pharmacokinetics and antitumor therapeutic efficacy
-
Papahadjopoulos D, Allen TM, Gabizon A, et al. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc Natl Acad Sci U S A 1991; 88: 11460-4
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 11460-11464
-
-
Papahadjopoulos, D.1
Allen, T.M.2
Gabizon, A.3
-
41
-
-
0030669086
-
Polyethylene glycol-coated (pegylated) liposomal doxorubicin: Rationale for use in solid tumours
-
Gabizon A, Martin F. Polyethylene glycol-coated (pegylated) liposomal doxorubicin: rationale for use in solid tumours. Drugs 1997; 54: 15-21
-
(1997)
Drugs
, vol.54
, pp. 15-21
-
-
Gabizon, A.1
Martin, F.2
-
42
-
-
0028324859
-
Pharmacokinetics, biodistribution and therapeutic efficacy of doxorubicin encapsulated in Stealth liposomes (Doxil®)
-
Working PK, Newman MS, Huang SK, et al. Pharmacokinetics, biodistribution and therapeutic efficacy of doxorubicin encapsulated in Stealth liposomes (Doxil®). J Liposome Res 1994; 4: 667-87
-
(1994)
J Liposome Res
, vol.4
, pp. 667-687
-
-
Working, P.K.1
Newman, M.S.2
Huang, S.K.3
-
43
-
-
0031045691
-
Tumor uptake of doxorubicin in polyethylene glycol-coated liposomes and therapeutic effect against a xenografted human pancreatic carcinoma
-
Vaage J, Donovan D, Uster P, et al. Tumor uptake of doxorubicin in polyethylene glycol-coated liposomes and therapeutic effect against a xenografted human pancreatic carcinoma. Br J Cancer 1997; 75: 482-6
-
(1997)
Br J Cancer
, vol.75
, pp. 482-486
-
-
Vaage, J.1
Donovan, D.2
Uster, P.3
-
44
-
-
0028219430
-
Tissue distribution and therapeutic effect of intravenous free or encapsulated liposomal doxorubicin on human prostate carcinoma xenografts
-
Vaage J, Barbera-Guillem E, Abra R, et al. Tissue distribution and therapeutic effect of intravenous free or encapsulated liposomal doxorubicin on human prostate carcinoma xenografts. Cancer 1994; 73: 1478-84
-
(1994)
Cancer
, vol.73
, pp. 1478-1484
-
-
Vaage, J.1
Barbera-Guillem, E.2
Abra, R.3
-
45
-
-
0031045691
-
Tumour uptake of doxorubicin in polyethylene glycol-coated liposomes and therapeutic effect against a xenografted human pancreatic carcinoma
-
Vaage J, Donovan D, Uster P, et al. Tumour uptake of doxorubicin in polyethylene glycol-coated liposomes and therapeutic effect against a xenografted human pancreatic carcinoma. Br J Cancer 1997; 75: 482-6
-
(1997)
Br J Cancer
, vol.75
, pp. 482-486
-
-
Vaage, J.1
Donovan, D.2
Uster, P.3
-
46
-
-
0026733476
-
Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice
-
Huang SK, Lee KD, Hong K, et al. Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res 1992; 52: 5135-43
-
(1992)
Cancer Res
, vol.52
, pp. 5135-5143
-
-
Huang, S.K.1
Lee, K.D.2
Hong, K.3
-
47
-
-
0028304405
-
Microvascular permeability and interstitial penetration of sterically stabilized (Stealth) liposomes in a human tumor xenograft
-
Yuan F, Leunig M, Huang SK, et al. Microvascular permeability and interstitial penetration of sterically stabilized (Stealth) liposomes in a human tumor xenograft. Cancer Res 1994; 54: 3352-6
-
(1994)
Cancer Res
, vol.54
, pp. 3352-3356
-
-
Yuan, F.1
Leunig, M.2
Huang, S.K.3
-
48
-
-
0026603586
-
Selective tumor localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes
-
Gabizon AA. Selective tumor localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes. Cancer Res 1992; 52: 891-6
-
(1992)
Cancer Res
, vol.52
, pp. 891-896
-
-
Gabizon, A.A.1
-
49
-
-
0028290796
-
Transfer of liposomal drug carriers from the blood to the peritoneal cavity of normal and ascitic tumor-bearing mice
-
Bally MB, Masin D, Nayar R, et al. Transfer of liposomal drug carriers from the blood to the peritoneal cavity of normal and ascitic tumor-bearing mice. Cancer Chemother Pharmacol 1994; 34: 137-46
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 137-146
-
-
Bally, M.B.1
Masin, D.2
Nayar, R.3
-
50
-
-
0030042023
-
Liposome longevity and stability in circulation: Effects on the in vivo delivery to tumors and therapeutic efficacy of encapsulated anthracyclines
-
Gabizon A, Chemla M, Tzemach D, et al. Liposome longevity and stability in circulation: effects on the in vivo delivery to tumors and therapeutic efficacy of encapsulated anthracyclines. J Drug Target 1996; 3: 391-8
-
(1996)
J Drug Target
, vol.3
, pp. 391-398
-
-
Gabizon, A.1
Chemla, M.2
Tzemach, D.3
-
51
-
-
0032713936
-
Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: Is surface coating with polyethylene glycol beneficial?
-
Hong RL, Huang CJ, Tseng YL, et al. Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial? Clin Cancer Res 1999; 5: 3645-52
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3645-3652
-
-
Hong, R.L.1
Huang, C.J.2
Tseng, Y.L.3
-
52
-
-
0032793990
-
Significant increase in antitumor potency of doxorubicin HCl by its encapsulation in pegylated liposomes
-
Colbern GT, Hiller AJ, Musterer RS, et al. Significant increase in antitumor potency of doxorubicin HCl by its encapsulation in pegylated liposomes. J Liposome Res 1999; 9: 523-38
-
(1999)
J Liposome Res
, vol.9
, pp. 523-538
-
-
Colbern, G.T.1
Hiller, A.J.2
Musterer, R.S.3
-
53
-
-
0029038996
-
Liposomal doxorubicin: Antitumor activity and unique toxicities during two complementary phase I studies
-
Uziely B, Jeffers S, Isacson R, et al. Liposomal doxorubicin: antitumor activity and unique toxicities during two complementary phase I studies. J Clin Oncol 1995; 13: 1777-85
-
(1995)
J Clin Oncol
, vol.13
, pp. 1777-1785
-
-
Uziely, B.1
Jeffers, S.2
Isacson, R.3
-
54
-
-
0031749555
-
Efficacy of pyridoxine to ameliorate the cutaneous toxicity associated with doxorubicin containing pegylated (Stealth) liposomes: A randomized, double-blind clinical trial using a canine model
-
Vail DM, Chun R, Thamm DH, et al. Efficacy of pyridoxine to ameliorate the cutaneous toxicity associated with doxorubicin containing pegylated (Stealth) liposomes: a randomized, double-blind clinical trial using a canine model. Clin Cancer Res 1998; 4: 1567-71
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1567-1571
-
-
Vail, D.M.1
Chun, R.2
Thamm, D.H.3
-
55
-
-
0032925683
-
Reduction of the cardiotoxicity of doxorubicin in rabbits and dogs by encapsulation in long-circulating, pegylated liposomes
-
Working PK, Newman MS, Sullivan T, et al. Reduction of the cardiotoxicity of doxorubicin in rabbits and dogs by encapsulation in long-circulating, pegylated liposomes. J Pharmacol Exp Ther 1999; 289: 1128-33
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1128-1133
-
-
Working, P.K.1
Newman, M.S.2
Sullivan, T.3
-
56
-
-
0028349925
-
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
-
Gabizon A, Catane R, Uziely B, et al. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res 1994; 54: 987-92
-
(1994)
Cancer Res
, vol.54
, pp. 987-992
-
-
Gabizon, A.1
Catane, R.2
Uziely, B.3
-
57
-
-
0036188460
-
Dose escalation and pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in children with solid tumors: A pediatric oncology group study
-
Marina NM, Cochrane D, Harney E, et al. Dose escalation and pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in children with solid tumors: a pediatric oncology group study. Clin Cancer Res 2002; 8: 413-8
-
(2002)
Clin Cancer Res
, vol.8
, pp. 413-418
-
-
Marina, N.M.1
Cochrane, D.2
Harney, E.3
-
58
-
-
0035340417
-
Phase I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors: The relation between pharmacokinetic property and toxicity
-
Hong RL, Tseng YL. Phase I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors: the relation between pharmacokinetic property and toxicity. Cancer 2001; 91: 1826-33
-
(2001)
Cancer
, vol.91
, pp. 1826-1833
-
-
Hong, R.L.1
Tseng, Y.L.2
-
59
-
-
0034284335
-
Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in metastatic breast carcinoma
-
Lyass O, Uziely B, Ben-Yosef R, et al. Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in metastatic breast carcinoma. Cancer 2000; 89: 1037-47
-
(2000)
Cancer
, vol.89
, pp. 1037-1047
-
-
Lyass, O.1
Uziely, B.2
Ben-Yosef, R.3
-
60
-
-
0036597855
-
EORTC 10968: A phase I clinical and pharmacokinetic study of polyethylene glycol liposomal doxorubicin (Caelyx®, Doxil®) at a 6-week interval in patients with metastatic breast cancer. European Organization for Research and Treatment of Cancer
-
Hamilton A, Biganzoli L, Coleman R, et al. EORTC 10968: a phase I clinical and pharmacokinetic study of polyethylene glycol liposomal doxorubicin (Caelyx®, Doxil®) at a 6-week interval in patients with metastatic breast cancer. European Organization for Research and Treatment of Cancer. Ann Oncol 2002; 13: 910-8
-
(2002)
Ann Oncol
, vol.13
, pp. 910-918
-
-
Hamilton, A.1
Biganzoli, L.2
Coleman, R.3
-
61
-
-
0034126252
-
Doxil® (Caelyx®): An exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer
-
Hubert A, Lyass O, Pode D, et al. Doxil® (Caelyx®): an exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer. Anticancer Drugs 2000; 11: 123-7
-
(2000)
Anticancer Drugs
, vol.11
, pp. 123-127
-
-
Hubert, A.1
Lyass, O.2
Pode, D.3
-
62
-
-
0030898351
-
Population pharmacokinetics and pharmacodynamics of pegylated-liposomal doxorubicin in patients with AIDS-related Kaposi's sarcoma
-
Amantea MA, Forrest A, Northfelt DW, et al. Population pharmacokinetics and pharmacodynamics of pegylated-liposomal doxorubicin in patients with AIDS-related Kaposi's sarcoma. Clin Pharmacol Ther 1997; 61: 301-11
-
(1997)
Clin Pharmacol Ther
, vol.61
, pp. 301-311
-
-
Amantea, M.A.1
Forrest, A.2
Northfelt, D.W.3
-
63
-
-
0030024958
-
Doxorubicin encapsulated in liposomes containing surface-bound polyethylene glycol: Pharmacokinetics, tumor localization, and safety in patients with AIDS-related Kaposi's sarcoma
-
Northfelt DW, Martin FJ, Working P, et al. Doxorubicin encapsulated in liposomes containing surface-bound polyethylene glycol: pharmacokinetics, tumor localization, and safety in patients with AIDS-related Kaposi's sarcoma. J Clin Pharmacol 1996; 36: 55-63
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 55-63
-
-
Northfelt, D.W.1
Martin, F.J.2
Working, P.3
-
64
-
-
0020038042
-
Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion
-
Legha SS, Benjamin RS, Mackay B, et al. Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion. Ann Intern Med 1982; 96: 133-9
-
(1982)
Ann Intern Med
, vol.96
, pp. 133-139
-
-
Legha, S.S.1
Benjamin, R.S.2
Mackay, B.3
-
65
-
-
0000220985
-
Doxorubicin encapsulated in polyethylene glycol-coated liposomes: Initial clinical-pharmacokinetic studies in solid tumors
-
Lasic DD, Martin FJ, editors. Boca Raton: CRC Press
-
Gabizon A, Huang A, Martin F, et al. Doxorubicin encapsulated in polyethylene glycol-coated liposomes: initial clinical-pharmacokinetic studies in solid tumors. In: Lasic DD, Martin FJ, editors. Stealth liposomes. Boca Raton: CRC Press, 1995: 251-61
-
(1995)
Stealth Liposomes
, pp. 251-261
-
-
Gabizon, A.1
Huang, A.2
Martin, F.3
-
66
-
-
0030959798
-
Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: Results of a multicenter phase II trial
-
Ranson MR, Carmichael J, O'Byrne K, et al. Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. J Clin Oncol 1997; 15: 3185-91
-
(1997)
J Clin Oncol
, vol.15
, pp. 3185-3191
-
-
Ranson, M.R.1
Carmichael, J.2
O'Byrne, K.3
-
67
-
-
0034109686
-
Liposomal doxorubicin (Caelyx) in advanced pretreated soft tissue sarcomas: A phase II study of the Italian Sarcoma Group (ISG)
-
Toma S, Tucci A, Villani G, et al. Liposomal doxorubicin (Caelyx) in advanced pretreated soft tissue sarcomas: a phase II study of the Italian Sarcoma Group (ISG). Anticancer Res 2000; 20: 485-91
-
(2000)
Anticancer Res
, vol.20
, pp. 485-491
-
-
Toma, S.1
Tucci, A.2
Villani, G.3
-
68
-
-
0031795043
-
A phase II study of Doxil® (liposomal doxorubicin): Lack of activity in poor prognosis soft tissue sarcomas
-
Garcia AA, Kempf RA, Rogers M, et al. A phase II study of Doxil® (liposomal doxorubicin): lack of activity in poor prognosis soft tissue sarcomas. Ann Oncol 1998; 9: 1131-3
-
(1998)
Ann Oncol
, vol.9
, pp. 1131-1133
-
-
Garcia, A.A.1
Kempf, R.A.2
Rogers, M.3
-
69
-
-
0003015811
-
Initial clinical evaluation of pegylated liposomal doxorubicin in solid tumors
-
Woodle M, Storm G, editors. Austin: Landes Bioscience
-
Gabizon AA, Muggia FM. Initial clinical evaluation of pegylated liposomal doxorubicin in solid tumors. In: Woodle M, Storm G, editors. Long-circulating liposomes: old drugs, new therapeutics. Austin: Landes Bioscience, 1998: 165-74
-
(1998)
Long-circulating Liposomes: Old Drugs, New Therapeutics
, pp. 165-174
-
-
Gabizon, A.A.1
Muggia, F.M.2
-
70
-
-
0034793680
-
Phase I study of doxilcisplatin combination chemotherapy in patients with advanced malignancies
-
Lyass O, Hubert A, Gabizon AA. Phase I study of doxilcisplatin combination chemotherapy in patients with advanced malignancies. Clin Cancer Res 2001; 7: 3040-6
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3040-3046
-
-
Lyass, O.1
Hubert, A.2
Gabizon, A.A.3
-
71
-
-
0030731376
-
Liposomal anthracycline chemotherapy in the treatment of AIDS-related Kaposi' s sarcoma
-
Northfelt DW. Liposomal anthracycline chemotherapy in the treatment of AIDS-related Kaposi' s sarcoma. Oncology 1997; 11: 21-32
-
(1997)
Oncology
, vol.11
, pp. 21-32
-
-
Northfelt, D.W.1
-
72
-
-
0033168435
-
Selective delivery of doxorubicin to patients with breast carcinoma metastases by stealth liposomes
-
Symon Z, Peyser A, Tzemach D, et al. Selective delivery of doxorubicin to patients with breast carcinoma metastases by stealth liposomes. Cancer 1999; 86: 72-8
-
(1999)
Cancer
, vol.86
, pp. 72-78
-
-
Symon, Z.1
Peyser, A.2
Tzemach, D.3
-
73
-
-
0035127410
-
Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes
-
Harrington KJ, Mohammadtaghi S, Uster PS, et al. Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. Clin Cancer Res 2001; 7: 243-54
-
(2001)
Clin Cancer Res
, vol.7
, pp. 243-254
-
-
Harrington, K.J.1
Mohammadtaghi, S.2
Uster, P.S.3
-
74
-
-
0035165412
-
Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: Analysis of toxicities and predictors of outcome
-
Safra T, Groshen S, Jeffers S, et al. Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome. Cancer 2001; 91: 90-100
-
(2001)
Cancer
, vol.91
, pp. 90-100
-
-
Safra, T.1
Groshen, S.2
Jeffers, S.3
-
75
-
-
0032700799
-
Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer
-
Koukourakis MI, Koukouraki S, Giatromanolaki A, et al. Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer. J Clin Oncol 1999; 17: 3512-21
-
(1999)
J Clin Oncol
, vol.17
, pp. 3512-3521
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Giatromanolaki, A.3
-
76
-
-
0033734065
-
High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours
-
Koukourakis MI, Koukouraki S, Fezoulidis I, et al. High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours. Br J Cancer 2000; 83: 1281-6
-
(2000)
Br J Cancer
, vol.83
, pp. 1281-1286
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Fezoulidis, I.3
-
77
-
-
0034065024
-
High intratumoral accumulation of stealth liposomal doxorubicin in sarcomas - Rationale for combination with radiotherapy
-
Koukourakis MI, Koukouraki S, Giatromanolaki A, et al. High intratumoral accumulation of stealth liposomal doxorubicin in sarcomas - rationale for combination with radiotherapy. Acta Oncol 2000; 39: 207-11
-
(2000)
Acta Oncol
, vol.39
, pp. 207-211
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Giatromanolaki, A.3
-
78
-
-
0033802643
-
Pegylated liposomal doxorubicin (doxil): Reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2
-
Safra T, Muggia F, Jeffers S, et al. Pegylated liposomal doxorubicin (doxil): reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2. Ann Oncol 2000; 11: 1029-33
-
(2000)
Ann Oncol
, vol.11
, pp. 1029-1033
-
-
Safra, T.1
Muggia, F.2
Jeffers, S.3
|