Nanoparticle uptake: The phagocyte problem

Nano Today

Volumn 10, Issue 4, 2015, Pages 487-510

  Gustafson, Heather Herd ^a,b   Holt Casper, Dolly ^a   Grainger, David W ^a,b   Ghandehari, Hamidreza ^a,b  

^a Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Biodistribution; Clearance; Drug delivery; Imaging; Macrophage; Toxicity

Indexed keywords

DRUG DELIVERY; IMAGING TECHNIQUES; MACROPHAGES; NANOPARTICLES; TOXICITY;

BIODISTRIBUTIONS; BIOLOGICAL RESPONSE; CLEARANCE; HOST RESPONSE; INFLAMMATORY PROCESS; NANOMATERIAL; NANOPARTICLE UPTAKES; PRIMARY CELLS;

NANOSTRUCTURED MATERIALS;

CELL RECEPTOR; NANOMATERIAL; NANOPARTICLE;

ADSORPTION; AUTOPHAGY; CELL FATE; CELL INTERACTION; CELL SURFACE; COMPLEMENT ACTIVATION; DRUG DELIVERY SYSTEM; ENVIRONMENTAL FACTOR; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTERNALIZATION; MACROPHAGE; MOLECULAR RECOGNITION; NANOTOXICOLOGY; NONHUMAN; PHAGOCYTE; PHENOTYPE; REVIEW;

EID: 84949322229     PISSN: 17480132     EISSN: 1878044X     Source Type: Journal    
DOI: 10.1016/j.nantod.2015.06.006     Document Type: Review

References (273)

1. T.M. Allen, and P.R. Cullis Science 303 2004 1818 1822
2. M.L. Etheridge, S.A. Campbell, A.G. Erdman, C.L. Haynes, S.M. Wolf, and J. McCullough Nanomedicine 9 2013 1 14
3. W.P. Caron, G. Song, P. Kumar, S. Rawal, and W.C. Zamboni Clin. Pharmacol. Ther. 91 2012 802 812
4. W.P. Caron, J.C. Lay, A.M. Fong, N.M. La-Beck, P. Kumar, S.E. Newman, H. Zhou, J.H. Monaco, D.L. Clarke-Pearson, W.R. Brewster, L. Van Le, V.L. Bae-Jump, P.A. Gehrig, and W.C. Zamboni J. Pharmacol. Exp. Ther. 347 2013 599 606
5. X. He, H. Nie, K. Wang, W. Tan, X. Wu, and P. Zhang Anal. Chem. 80 2008 9597 9603
6. X. Huang, L. Li, T. Liu, N. Hao, H. Liu, D. Chen, and F. Tang ACS Nano 5 2011 5390 5399
7. R. Kumar, I. Roy, T.Y. Ohulchanskky, L.A. Vathy, E.J. Bergey, M. Sajjad, and P.N. Prasad ACS Nano 4 2010 699 708
8. T. Liu, L. Li, X. Teng, X. Huang, H. Liu, D. Chen, J. Ren, J. He, and F. Tang Biomaterials 32 2011 1657 1668
9. Y. Liu, Y. Hu, and L. Huang Biomaterials 35 2014 3027 3034
10. K. Ohno, T. Akashi, Y. Tsujii, M. Yamamoto, and Y. Tabata Biomacromolecules 13 2012 927 936
11. D.E. Owens, N.A. 3rd, and Peppas Int. J. Pharm. 307 2006 93 102
12. A. Albanese, E.A. Sykes, and W.C. Chan ACS Nano 4 2010 2490 2493
13. J.M. Carter, and K.E. Driscoll J. Environ. Pathol. Toxicol. Oncol. 20 Suppl 1 2001 S33 S43
14. W.S. Cho, M. Choi, B.S. Han, M. Cho, J. Oh, K. Park, S.J. Kim, S.H. Kim, and J. Jeong Toxicol. Lett. 175 2007 24 33
15. K.E. Driscoll Toxicol. Lett. 112-113 2000 177 183
16. U. Gazi, and L. Martinez-Pomares Immunobiology 214 2009 554 561
17. R.P. Nishanth, R.G. Jyotsna, J.J. Schlager, S.M. Hussain, and P. Reddanna Nanotoxicology 5 2011 502 516
18. G.A. Orr, W.B. Chrisler, K.J. Cassens, R. Tan, B.J. Tarasevich, L.M. Markillie, R.C. Zangar, and B.D. Thrall Nanotoxicology 5 2011 296 311
19. J. Pajarinen, V.P. Kouri, E. Jamsen, T.F. Li, J. Mandelin, and Y.T. Konttinen Acta Biomater. 9 2013 9229 9240
20. E.J. Park, and K. Park Toxicol. Lett. 184 2009 18 25
21. G. Sharma, D.T. Valenta, Y. Altman, S. Harvey, H. Xie, S. Mitragotri, and J.W. Smith J. Control. Release 147 2010 408 412
22. F. Velard, J. Braux, J. Amedee, and P. Laquerriere Acta Biomater. 9 2013 4956 4963
23. Y.H. Bae, and K. Park J. Control. Release 153 2011 198 205
24. A.T. Florence J. Control. Release 164 2012 115 124
25. D.J. Crommelin, and A.T. Florence Int. J. Pharm. 454 2013 496 511
26. Y. Wang, and D.W. Grainger FCHEM 8 2014 265 275
27. M.A. Dobrovolskaia, and S.E. McNeil Nat. Nanotechnol. 2 2007 469 478
28. M.A. Dobrovolskaia, P. Aggarwal, J.B. Hall, and S.E. McNeil Mol. Pharm. 5 2008 487 495
29. M.A. Dobrovolskaia, and S.E. McNeil J. Control. Release 172 2013 456 466
30. M.A. Dobrovolskaia, D.R. Germolec, and J.L. Weaver Nat. Nanotechnol. 4 2009 411 414
31. G.M. Mortimer, N.J. Butcher, A.W. Musumeci, Z.J. Deng, D.J. Martin, and R.F. Minchin ACS Nano 8 2014 3357 3366
32. C.R. Jenkin, and D. Rowley J. Exp. Med. 114 1961 363 374
33. D. Pouliquen, J. Le Jeune, R. Perdrisot, A. Ermias, and P. Jallet J. Magn. Reson. Imaging 9 1991 275 283
34. K. Briley-Saebo, A. Bjornerud, D. Grant, H. Ahlstrom, T. Berg, and G.M. Kindberg Cell Tissue Res. 316 2004 315 323
35. P. Aggarwal, J.B. Hall, C.B. McLeland, M.A. Dobrovolskaia, and S.E. McNeil Adv. Drug Deliv. Rev. 61 2009 428 437
36. A. Albanese, P.S. Tang, and W.C. Chan Annu. Rev. Biomed. Eng. 14 2012 1 16
37. K. Greish, G. Thiagarajan, and H. Ghandehari Methods Mol. Biol. 926 2012 235 253
38. P.P. Karmali, and D. Simberg Expert Opin. Drug Deliv. 8 2011 343 357
39. C.D. Walkey, J.B. Olsen, H. Guo, A. Emili, and W.C. Chan J. Am. Chem. Soc. 134 2012 2139 2147
40. B. Fubini, and A. Hubbard Free Radic. Biol. Med. 34 2003 1507 1516
41. M. Zhu, G. Nie, H. Meng, T. Xia, A. Nel, and Y. Zhao Acc. Chem. Res. 46 2013 622 631
42. M.I. Khan, A. Mohammad, G. Patil, S.A. Naqvi, L.K. Chauhan, and I. Ahmad Biomaterials 33 2012 1477 1488
43. O. Lunov, T. Syrovets, C. Loos, G.U. Nienhaus, V. Mailander, K. Landfester, M. Rouis, and T. Simmet ACS Nano 5 2011 9648 9657
44. F. Wang, F. Gao, M. Lan, H. Yuan, Y. Huang, and J. Liu Toxicol. In Vitro 23 2009 808 815
45. T. Xia, M. Kovochich, J. Brant, M. Hotze, J. Sempf, T. Oberley, C. Sioutas, J.I. Yeh, M.R. Wiesner, and A.E. Nel Nano Lett. 6 2006 1794 1807
46. A.C. Allison Arch. Intern. Med. 128 1971 131 139
47. B. Mossman, W. Light, and E. Wei Annu. Rev. Pharmacol. Toxicol. 23 1983 595 615
48. A.C. Allison, J.S. Harington, and M. Birbeck J. Exp. Med. 124 1966 141 154
49. N. Fujimura Curr. Opin. Pulm. Med. 6 2000 140 144
50. B.T. Mossman, and A. Churg Am. J. Respir. Crit. Care Med. 157 1998 1666 1680
51. J.D. Byrne, and J.A. Baugh Mcgill J. Med. 11 2008 43 50
52. H. Nishimori, M. Kondoh, K. Isoda, S. Tsunoda, Y. Tsutsumi, and K. Yagi Eur. J. Pharm. Biopharm. 72 2009 496 501
53. B. Rimal, A.K. Greenberg, and W.N. Rom Curr. Opin. Pulm. Med. 11 2005 169 173
54. H.S. Choi, Y. Ashitate, J.H. Lee, S.H. Kim, A. Matsui, N. Insin, M.G. Bawendi, M. Semmler-Behnke, J.V. Frangioni, and A. Tsuda Nat. Biotechnol. 28 2010 1300 1303
55. C. Terzano, F. Di Stefano, V. Conti, E. Graziani, and A. Petroianni Eur. Rev. Med. Pharmacol. Sci. 14 2010 809 821
56. B. Burke, and C.E. Lewis The Macrophage 2002 Oxford University Press New York
57. C. Shi, and E.G. Pamer Nat. Rev. Immunol. 11 2011 762 774
58. P.J. Murray, and T.A. Wynn Nat. Rev. Immunol. 11 2011 723 737
59. H. Matsui, T. Ito, and S. Ohnishi J. Cell. Sci. 59 1983 133 143
60. R.H. Michell, S.J. Pancake, J. Noseworthy, and M.L. Karnovsky J. Cell. Biol. 40 1969 216 224
61. S. Epelman, K.J. Lavine, and G.J. Randolph Immunity 41 2014 21 35
62. D.M. Mosser, and J.P. Edwards Nat. Rev. Immunol. 8 2008 958 969
63. A. Mantovani, S.K. Biswas, M.R. Galdiero, A. Sica, and M. Locati J. Pathol. 229 2013 176 185
64. M. Locati, A. Mantovani, and A. Sica Adv. Immunol. 120 2013 163 184
65. G.J. Nau, J.F. Richmond, A. Schlesinger, E.G. Jennings, E.S. Lander, and R.A. Young Proc. Natl. Acad. Sci. U. S. A. 99 2002 1503 1508
66. S. Akira, S. Uematsu, and O. Takeuchi Cell 124 2006 783 801
67. J.M. Anderson, A. Rodriguez, and D.T. Chang Semin. Immunol. 20 2008 86 100
68. L. Cassetta, E. Cassol, and G. Poli Sci. World 11 2011 2391 2402
69. F.O. Martinez, A. Sica, A. Mantovani, and M. Locati Front. Biosci. 13 2008 453 461
70. H.L. Herd, K.T. Bartlett, J.A. Gustafson, L.D. McGill, and H. Ghandehari Biomaterials 53 2015 574 582
71. J.L. Shepard, and L.I. Zon Curr. Opin. Hematol. 7 2000 3 8
72. T.A. Wynn, A. Chawla, and J.W. Pollard Nature 496 2013 445 455
73. M. Haldar, and K.M. Murphy Immunol. Rev. 262 2014 25 35
74. L.C. Davies, S.J. Jenkins, J.E. Allen, and P.R. Taylor Nat. Immunol. 14 2013 986 995
75. R. Juliano Adv. Drug Deliv. Rev. 2 1988 31 54
76. G. Borchardt, S. Brandriss, J. Kreuter, and S. Margel J. Drug Target. 2 1994 61 77
77. S.M. Moghimi, I.S. Muir, L. Illum, S.S. Davis, and V. Kolb-Bachofen Biochim. Biophys. Acta 1179 1993 157 165
78. Y. Shibata, L.A. Foster, W.J. Metzger, and Q.N. Myrvik Infect. Immun. 65 1997 1734 1741
79. D.J. Holt, and D.W. Grainger Biomaterials 33 2012 7497 7507
80. B. Ruffell, N.I. Affara, and L.M. Coussens Trends Immunol. 33 2012 119 126
81. P.J. Murray, J.E. Allen, S.K. Biswas, E.A. Fisher, D.W. Gilroy, S. Goerdt, S. Gordon, J.A. Hamilton, L.B. Ivashkiv, T. Lawrence, M. Locati, A. Mantovani, F.O. Martinez, J.L. Mege, D.M. Mosser, G. Natoli, J.P. Saeij, J.L. Schultze, K.A. Shirey, A. Sica, J. Suttles, I. Udalova, J.A. van Ginderachter, S.N. Vogel, and T.A. Wynn Immunity 41 2014 14 20
82. J. Hoppstadter, M. Seif, A. Dembek, C. Cavelius, H. Huwer, A. Kraegeloh, and A.K. Kiemer Front. Pharmacol. 6 2015 55
83. J.D. Andrade, and V. Hlady Biopolymers/Non-Exclusion HPLC 1986 Springer Berlin Heidelberg 1 63
84. J.D. Andrade, V.L. Hlady, and R.A. Van Wagenen Pure Appl. Chem. 56 1984 1345 1350
85. J. Senior, C. Delgado, D. Fisher, C. Tilcock, and G. Gregoriadis Biochim. Biophys. Acta 1062 1991 77 82
86. J. Senior, J.C. Crawley, and G. Gregoriadis Biochim. Biophys. Acta 839 1985 1 8
87. Y. Chao, P.P. Karmali, R. Mukthavaram, S. Kesari, V.L. Kouznetsova, I.F. Tsigelny, and D. Simberg ACS Nano 7 2013 4289 4298
88. A.E. Nel, L. Madler, D. Velegol, T. Xia, E.M. Hoek, P. Somasundaran, F. Klaessig, V. Castranova, and M. Thompson Nat. Mater. 8 2009 543 557
89. I. Lynch, and K.A. Dawson Nano Today 3 2008 40 47
90. D.W. Grainger, and D.G. Castner Adv. Mater. 20 2008 867 877
91. D.R. Absolom Methods Enzymol. 132 1986 281 318
92. A.A. Vertegel, R.W. Siegel, and J.S. Dordick Langmuir 20 2004 6800 6807
93. W.S. Davidson, A. Jonas, D.F. Clayton, and J.M. George J. Biol. Chem. 273 1998 9443 9449
94. P. Roach, D. Farrar, and C.C. Perry J. Am. Chem. 128 2006 3939 3945
95. M.S. Lord, M. Foss, and F. Besenbacher Nano Today 5 2010 66 78
96. A. Dolatshahi-Pirouz, K. Rechendorff, M.B. Hovgaard, M. Foss, J. Chevallier, and F. Besenbacher Colloids Surf. B 66 2008 53 59
97. C.D. Walkey, and W.C. Chan Chem. Soc. Rev. 41 2012 2780 2799
98. N.K. Banda, G. Mehta, Y. Chao, G. Wang, S. Inturi, L. Fossati-Jimack, M. Botto, L. Wu, S.M. Moghimi, and D. Simberg Part Fibre Toxicol. 11 2014 64
99. M.P. Monopoli, C. Aberg, A. Salvati, and K.A. Dawson Nat. Nanotechnol. 7 2012 779 786
100. S. Gordon Cell 111 2002 927 930
101. C.A. Janeway Jr., and R. Medzhitov Annu. Rev. Immunol. 20 2002 197 216
102. T. Boller, and G. Felix Annu. Rev. Plant Biol. 60 2009 379 406
103. Y. Kumagai, and S. Akira J. Allergy Clin. Immunol. 125 2010 985 992
104. H. Singh, Encyclopedia of Systems Biology, (2013) 517-517.
105. M.A. Collier, M.D. Gallovic, K.J. Peine, A.D. Duong, E.M. Bachelder, J.S. Gunn, L.S. Schlesinger, and K.M. Ainslie Expert Rev. Anti Infect. Ther. 11 2013 1225 1235
106. M.A. Delgado, R.A. Elmaoued, A.S. Davis, G. Kyei, and V. Deretic EMBO J. 27 2008 1110 1121
107. P.K. Anand, S.W. Tait, M. Lamkanfi, A.O. Amer, G. Nunez, G. Pages, J. Pouyssegur, M.A. McGargill, D.R. Green, and T.D. Kanneganti J. Biol. Chem. 286 2011 42981 42991
108. J. Lu, Z. Li, J.I. Zink, and F. Tamanoi Nanomedicine 8 2012 212 220
109. K. Schroder, and J. Tschopp Cell 140 2010 821 832
110. J.J. Moon, H. Suh, M.E. Polhemus, C.F. Ockenhouse, A. Yadava, and D.J. Irvine PLoS One 7 2012 e31472
111. S.L. Demento, S.C. Eisenbarth, H.G. Foellmer, C. Platt, M.J. Caplan, W. Mark Saltzman, I. Mellman, M. Ledizet, E. Fikrig, R.A. Flavell, and T.M. Fahmy Vaccine 27 2009 3013 3021
112. M.W. Turner Immunol. Today 17 1996 532 540
113. A.V. Chavez-Santoscoy, R. Roychoudhury, N.L. Pohl, M.J. Wannemuehler, B. Narasimhan, and A.E. Ramer-Tait Biomaterials 33 2012 4762 4772
114. W.I. Weis, and K. Drickamer Structure 2 1994 1227 1240
115. H. Connaris, P.R. Crocker, and G.L. Taylor J. Biol. Chem. 284 2009 7339 7351
116. S.K. Jain, Y. Gupta, A. Jain, A.R. Saxena, P. Khare, and A. Jain Nanomedicine 4 2008 41 48
117. A. Kaur, S. Jain, and A.K. Tiwary Acta Pharm. 58 2008 61 74
118. Y. Luo, H. Zhou, J. Krueger, C. Kaplan, S.-H. Lee, C. Dolman, D. Markowitz, W. Wu, C. Liu, and R.A. Reisfeld J. Clin. Invest. 116 2006 2132 2141
119. T. Keler, V. Ramakrishna, and M.W. Fanger Expert Opin. Biol. Ther. 4 2004 1953 1962
120. M. Gary-Bobo, Y. Mir, C. Rouxel, D. Brevet, I. Basile, M. Maynadier, O. Vaillant, O. Mongin, M. Blanchard-Desce, A. Morere, M. Garcia, J.O. Durand, and L. Raehm Angew. Chem. Int. Ed. Engl. 50 2011 11425 11429
121. S. Kanno, A. Furuyama, and S. Hirano Toxicol. Sci. 97 2007 398 406
122. L. Peiser, S. Mukhopadhyay, and S. Gordon Curr. Opin. Immunol. 14 2002 123 128
123. J. Canton, D. Neculai, and S. Grinstein Nat. Rev. Immunol. 13 2013 621 634
124. A. Pluddemann, C. Neyen, and S. Gordon Methods 43 2007 207 217
125. O. Lunov, V. Zablotskii, T. Syrovets, C. Rocker, K. Tron, G.U. Nienhaus, and T. Simmet Biomaterials 32 2011 547 555
126. G. Le Duc, L. Vander Elst, J.M. Colet, A. Roch, P. Gillis, J.F. Le Bas, and R.N. Muller J. Magn. Reson. Imaging 13 2001 619 626
127. A. Aderem, and D.M. Underhill Annu. Rev. Immunol. 17 1999 593 623
128. N.C. Bell, C. Minelli, and A.G. Shard Anal. Methods 5 2013 4591 4601
129. N. Khlebtsov, V. Bogatyrev, B. Khlebtsov, L. Dykman, and P. Englebienne Colloid J. 65 2003 622 635
130. J.S. Bee, D. Chiu, S. Sawicki, J.L. Stevenson, K. Chatterjee, E. Freund, J.F. Carpenter, and T.W. Randolph J. Pharm. Sci. 98 2009 3218 3238
131. P.R. Taylor, L. Martinez-Pomares, M. Stacey, H.H. Lin, G.D. Brown, and S. Gordon Annu. Rev. Immunol. 23 2005 901 944
132. A. Lesniak, F. Fenaroli, M.P. Monopoli, C. Aberg, K.A. Dawson, and A. Salvati ACS Nano 6 2012 5845 5857
133. D. Dutta, S.K. Sundaram, J.G. Teeguarden, B.J. Riley, L.S. Fifield, J.M. Jacobs, S.R. Addleman, G.A. Kaysen, B.M. Moudgil, and T.J. Weber Toxicol. Sci. 100 2007 303 315
134. H. Herd, N. Daum, A.T. Jones, H. Huwer, H. Ghandehari, and C.M. Lehr ACS Nano 7 2013 1961 1973
135. H. Herd, and H. Ghandehari Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications 2011 CRC Press Boca Raton, FL
136. M.-I. Walters, J.M. Papadimitriou, and W. Spector CRC Crit. Rev. Toxicol. 5 1978 377 421
137. J. Monks, D. Rosner, F.J. Geske, L. Lehman, L. Hanson, M. Neville, and V. Fadok Cell Death Differ. 12 2005 107 114
138. M.R. de Jonge, L.H. Koymans, J.E. Guillemont, A. Koul, and K. Andries Proteins 67 2007 971 980
139. G.J. Doherty, and H.T. McMahon Annu. Rev. Biochem. 78 2009 857 902
140. S. Mayor, R.G. Parton, and J.G. Donaldson Cold Spring Harb. Perspect. Biol. 6 2014 a016758
141. S. Kumari, S. Mg, and S. Mayor Cell Res. 20 2010 256 275
142. O.L. Mooren, B.J. Galletta, and J.A. Cooper Annu. Rev. Biochem. 81 2012 661 686
143. K. Sandvig, S. Pust, T. Skotland, and B. van Deurs Curr. Opin. Cell Biol. 23 2011 413 420
144. H.T. McMahon, and E. Boucrot Nat. Rev. Mol. Cell. Biol. 12 2011 517 533
145. I. Canton, and G. Battaglia Chem. Soc. Rev. 41 2012 2718 2739
146. R.G. Parton, and A.A. Richards Traffic 4 2003 724 738
147. L. Pelkmans, T. Burli, M. Zerial, and A. Helenius Cell 118 2004 767 780
148. S.E. Gratton, P.A. Ropp, P.D. Pohlhaus, J.C. Luft, V.J. Madden, M.E. Napier, and J.M. DeSimone Proc. Natl. Acad. Sci U. S. A. 105 2008 11613 11618
149. J. Rejman, V. Oberle, I.S. Zuhorn, and D. Hoekstra Biochem. J. 377 2004 159 169
150. B.D. Chithrani, A.A. Ghazani, and W.C.W. Chan Nano Lett. 6 2006 662 668
151. B.D. Chithrani, and W.C. Chan Nano Lett. 7 2007 1542 1550
152. T.H. Chung, S.H. Wu, M. Yao, C.W. Lu, Y.S. Lin, Y. Hung, C.Y. Mou, Y.C. Chen, and D.M. Huang Biomaterials 28 2007 2959 2966
153. J.A. Champion, and S. Mitragotri Proc. Natl. Acad. Sci. U. S. A. 103 2006 4930 4934
154. J.A. Champion, Y.K. Katare, and S. Mitragotri Proc. Natl. Acad. Sci. U. S. A. 104 2007 11901 11904
155. P. Decuzzi, and M. Ferrari Biophys. J. 94 2008 3790 3797
156. W. Jiang, B.Y.S. Kim, J.T. Rutka, and W.C.W. Chan Nat. Nanotechnol. 3 2008 145 150
157. J. Haensler, and F.C. Szoka Jr. Bioconjug. Chem. 4 1993 372 379
158. D. Fischer, T. Bieber, Y. Li, H.P. Elsasser, and T. Kissel Pharm. Res. 16 1999 1273 1279
159. M. Roser, D. Fischer, and T. Kissel Eur. J. Pharm. Biopharm. 46 1998 255 263
160. F. Chellat, Y. Merhi, A. Moreau, and L. Yahia Biomaterials 26 2005 7260 7275
161. H. Yuan, J. Li, G. Bao, and S. Zhang Phys. Rev. Lett. 105 2010 138101
162. V. Deretic, T. Saitoh, and S. Akira Nat. Rev. Immunol. 13 2013 722 737
163. R.F. Hamilton Jr., S.A. Thakur, J.K. Mayfair, and A. Holian J. Biol. Chem. 281 2006 34218 34226
164. G. Petrovski, G. Zahuczky, G. Majai, and L. Fesus Autophagy 3 2007 509 511
165. C. Fiuza, M. Bustin, S. Talwar, M. Tropea, E. Gerstenberger, J.H. Shelhamer, and A.F. Suffredini Blood 101 2003 2652 2660
166. X.D. Zhang, D. Wu, X. Shen, P.X. Liu, F.Y. Fan, and S.J. Fan Biomaterials 33 2012 4628 4638
167. M.E. Davis, J.E. Zuckerman, C.H. Choi, D. Seligson, A. Tolcher, C.A. Alabi, Y. Yen, J.D. Heidel, and A. Ribas Nature 464 2010 1067 1070
168. D. Vercauteren, H. Deschout, K. Remaut, J.F. Engbersen, A.T. Jones, J. Demeester, S.C. De Smedt, and K. Braeckmans ACS Nano 5 2011 7874 7884
169. H.L. Herd, A. Malugin, and H. Ghandehari J. Control. Release 153 2011 40 48
170. B. Levine, N. Mizushima, and H.W. Virgin Nature 469 2011 323 335
171. S.T. Stern, P.P. Adiseshaiah, and R.M. Crist Part Fibre Toxicol. 9 2012 20
172. D. Kanduc, A. Mittelman, R. Serpico, E. Sinigaglia, A.A. Sinha, C. Natale, R. Santacroce, M.G. Di Corcia, A. Lucchese, L. Dini, P. Pani, S. Santacroce, S. Simone, R. Bucci, and E. Farber Int. J. Oncol. 21 2002 165 170
173. M.D. Perez-Carrion, F.C. Perez-Martinez, S. Merino, P. Sanchez-Verdu, J. Martinez-Hernandez, R. Lujan, and V. Cena J. Neurochem. 120 2012 259 268
174. P.J. Vernon, and D. Tang Antioxid. Redox Signal. 18 2013 677 691
175. L. Wu, Y. Zhang, C. Zhang, X. Cui, S. Zhai, Y. Liu, C. Li, H. Zhu, G. Qu, and G. Jiang ACS Nano 8 2014 2087 2099
176. N. Mizushima, B. Levine, A.M. Cuervo, and D.J. Klionsky Nature 451 2008 1069 1075
177. A. Gupta, G. Pant, K. Mitra, J. Madan, M.K. Chourasia, and A. Misra Mol. Pharm. 11 2014 1201 1207
178. H.S. Kruth, J. Chang, I. Ifrim, and W.-Y. Zhang Eur. J. Cell. Biol. 78 1999 91 99
179. H.S. Kruth, S.I. Skarlatos, K. Lilly, J. Chang, and I. Ifrim J. Cell. Biol. 129 1995 133 145
180. M. Motskin, K.H. Müller, C. Genoud, A.G. Monteith, and J.N. Skepper Biomaterials 32 2011 9470 9482
181. T. Kirchhausen Annu. Rev. Cell Dev. Biol. 15 1999 705 732
182. R.V. Benjaminsen, M.A. Mattebjerg, J.R. Henriksen, S.M. Moghimi, and T.L. Andresen Mol. Ther. 21 2013 149 157
183. A. Szewczyk, and L. Wojtczak Pharmacol. Rev. 54 2002 101 127
184. S.V. Boddapati, G.G. D'Souza, S. Erdogan, V.P. Torchilin, and V. Weissig Nano Lett. 8 2008 2559 2563
185. A. Mukhopadhyay, and H. Weiner Adv. Drug Deliv. Rev. 59 2007 729 738
186. A. Hoshino, K. Fujioka, T. Oku, S. Nakamura, M. Suga, Y. Yamaguchi, K. Suzuki, M. Yasuhara, and K. Yamamoto Microbiol. Immunol. 48 2004 985 994
187. A.G. Tkachenko, H. Xie, Y. Liu, D. Coleman, J. Ryan, W.R. Glomm, M.K. Shipton, S. Franzen, and D.L. Feldheim Bioconjug. Chem. 15 2004 482 490
188. R. Misra, and S.K. Sahoo Eur. J. Pharm. Sci. 39 2010 152 163
189. C.W. Pouton, K.M. Wagstaff, D.M. Roth, G.W. Moseley, and D.A. Jans Adv. Drug Deliv. Rev. 59 2007 698 717
190. M.P. Murphy, and R.A. Smith Adv. Drug Deliv. Rev. 41 2000 235 250
191. C.F. Jones, and D.W. Grainger Adv. Drug Deliv. Rev. 61 2009 438 456
192. K. Pulskamp, S. Diabaté, and H.F. Krug Toxicol. Lett. 168 2007 58
193. A. Petri-Fink, B. Steitz, A. Finka, J. Salaklang, and H. Hofmann Eur. J. Pharm. Biopharm. 68 2008 129 137
194. A. Malugin, and H. Ghandehari Nanosci. Nanotechnol. Lett. 3 2011 309 313
195. G.N. Joshi, and D.A. Knecht Apoptosis 18 2013 271 285
196. C.C. Winterbourn Toxicol. Lett. 82-83 1995 969 974
197. N.S. Dalal, X.L. Shi, and V. Vallyathan J. Toxicol. Environ. Health 29 1990 307 316
198. W. Lin, Y.W. Huang, X.D. Zhou, and Y. Ma Toxicol. Appl. Pharmacol. 217 2006 252 259
199. K.M. Waters, L.M. Masiello, R.C. Zangar, B.J. Tarasevich, N.J. Karin, R.D. Quesenberry, S. Bandyopadhyay, J.G. Teeguarden, J.G. Pounds, and B.D. Thrall Toxicol. Sci. 107 2009 553 569
200. M.A. Shahbazi, M. Hamidi, E.M. Makila, H. Zhang, P.V. Almeida, M. Kaasalainen, J.J. Salonen, J.T. Hirvonen, and H.A. Santos Biomaterials 34 2013 7776 7789
201. S. Lee, H.S. Yun, and S.H. Kim Biomaterials 32 2011 9434 9443
202. H.C. Fischer, T.S. Hauck, A. Gomez-Aristizabal, and W.C. Chan Adv. Mater. 22 2010 2520 2524
203. L. Bregoli, F. Chiarini, A. Gambarelli, G. Sighinolfi, A.M. Gatti, P. Santi, A.M. Martelli, and L. Cocco Toxicology 262 2009 121 129
204. G. Oberdorster, A. Maynard, K. Donaldson, V. Castranova, J. Fitzpatrick, K. Ausman, J. Carter, B. Karn, W. Kreyling, D. Lai, S. Olin, N. Monteiro-Riviere, D. Warheit, H. Yang I.R.F.R.S.I.N.T.S.W. Group Part Fibre Toxicol. 2 2005 8
205. T.S. Hauck, R.E. Anderson, H.C. Fischer, S. Newbigging, and W.C. Chan Small 6 2010 138 144
206. M. Naito, G. Hasegawa, Y. Ebe, and T. Yamamoto Med. Electron. Microsc. 37 2004 16 28
207. K. Wake, K. Decker, A. Kirn, D. Knook, R. McCuskey, L. Bouwens, and E. Wisse Int. Rev. Cytol. 118 1988 173 229
208. G. Baffy J. Hepatol. 51 2009 212 223
209. S.M. Moghimi, A.C. Hunter, and J.C. Murray Pharmacol. Rev. 53 2001 283 318
210. M. Longmire, P.L. Choyke, and H. Kobayashi Nanomedicine 3 2008 703 717
211. M.J. Hardonk, G. Harms, and J. Koudstaal Histochemistry 83 1985 473 477
212. E. Sadauskas, G. Danscher, M. Stoltenberg, U. Vogel, A. Larsen, and H. Wallin Nanomedicine 5 2009 162 169
213. S.C. Gad, K.L. Sharp, C. Montgomery, J.D. Payne, and G.P. Goodrich Int. J. Toxicol. 31 2012 584 594
214. R.R. Arvizo, O.R. Miranda, D.F. Moyano, C.A. Walden, K. Giri, R. Bhattacharya, J.D. Robertson, V.M. Rotello, J.M. Reid, and P. Mukherjee PLoS One 6 2011 e24374
215. J.S. Souris, C.H. Lee, S.H. Cheng, C.T. Chen, C.S. Yang, J.A. Ho, C.Y. Mou, and L.W. Lo Biomaterials 31 2010 5564 5574
216. Q. He, Z. Zhang, F. Gao, Y. Li, and J. Shi Small 7 2011 271 280
217. S.T. Kim, K. Saha, C. Kim, and V.M. Rotello Acc. Chem. Res. 46 2013 681 691
218. M. Sarparanta, L.M. Bimbo, J. Rytkonen, E. Makila, T.J. Laaksonen, P. Laaksonen, M. Nyman, J. Salonen, M.B. Linder, J. Hirvonen, H.A. Santos, and A.J. Airaksinen Mol. Pharm. 9 2012 654 663
219. G. Gaucher, K. Asahina, J. Wang, and J.-C. Leroux Biomacromolecules 10 2009 408 416
220. J.R. Wingard, M.H. White, E. Anaissie, J. Raffalli, J. Goodman, A. Arrieta, and L.A.A.C.S. Group Clin. Infect. Dis. 31 2000 1155 1163
221. K. Sankhala, A. Mita, R. Adinin, L. Wood, M. Beeram, S. Bullock, N. Yamagata, K. Matsuno, T. Fujisawa, and A. Phan J. Clin. Oncol. 27 2009 2535
222. C.P. Leamon, and J.A. Reddy Adv. Drug Deliv. Rev. 56 2004 1127 1141
223. P. Puvanakrishnan, J. Park, D. Chatterjee, S. Krishnan, and J.W. Tunnell Int. J. Nanomed. 7 2012 1251 1258
224. M. Cho, W.S. Cho, M. Choi, S.J. Kim, B.S. Han, S.H. Kim, H.O. Kim, Y.Y. Sheen, and J. Jeong Toxicol Lett. 189 2009 177 183
225. S.M. Hirst, A. Karakoti, S. Singh, W. Self, R. Tyler, S. Seal, and C.M. Reilly Environ. Toxicol. 28 2013 107 118
226. H. Zreiqat, R.K. Kumar, B. Markovic, B. Zicat, and C.R. Howlett J. Biomed. Mater. Res. A 65 2003 109 117
227. G.E. Garrigues, D.R. Cho, H.E. Rubash, S.R. Goldring, J.H. Herndon, and A.S. Shanbhag Biomaterials 26 2005 2933 2945
228. B.W. Neun, and M.A. Dobrovolskaia Methods Mol. Biol. 697 2011 237 245
229. S.N. Thomas, A.J. van der Vlies, C.P. O'Neil, S.T. Reddy, S.S. Yu, T.D. Giorgio, M.A. Swartz, and J.A. Hubbell Biomaterials 32 2011 2194 2203
230. J. Szebeni, L. Baranyi, S. Savay, J. Milosevits, R. Bunger, P. Laverman, J.M. Metselaar, G. Storm, A. Chanan-Khan, L. Liebes, F.M. Muggia, R. Cohen, Y. Barenholz, and C.R. Alving J. Liposome Res. 12 2002 165 172
231. M.B. Pedersen, X. Zhou, E.K.U. Larsen, U.S. Sørensen, J. Kjems, J.V. Nygaard, J.R. Nyengaard, R.L. Meyer, T. Boesen, and T. Vorup-Jensen J. Immun. 184 2010 1931 1945
232. G.D. Ross, W. Reed, J.G. Dalzell, S.E. Becker, and N. Hogg J. Leukoc. Biol. 51 1992 109 117
233. S.M. Moghimi, and J. Szebeni Prog. Lipid Res. 42 2003 463 478
234. M. van Lookeren Campagne, C. Wiesmann, and E.J. Brown Cell Microbiol. 9 2007 2095 2102
235. C. Corot, P. Robert, J.M. Idee, and M. Port Adv. Drug Deliv. Rev. 58 2006 1471 1504
236. M. Hamidi, A. Azadi, and P. Rafiei Drug Deliv. 13 2006 399 409
237. J.-W. Yoo, E. Chambers, and S. Mitragotri Curr. Pharm. Design. 16 2010 2298 2307
238. S.M. Moghimi, H. Hedeman, N.M. Christy, L. Illum, and S.S. Davis J. Leukoc. Biol. 54 1993 513 517
239. S.M. Moghimi, A.J. Andersen, D. Ahmadvand, P.P. Wibroe, T.L. Andresen, and A.C. Hunter Adv. Drug Deliv. Rev. 63 2011 1000 1007
240. K. Greish, G. Thiagarajan, H. Herd, R. Price, H. Bauer, D. Hubbard, A. Burckle, S. Sadekar, T. Yu, and A. Anwar Nanotoxicology 6 2012 713 723
241. A. Radomski, P. Jurasz, D. Alonso-Escolano, M. Drews, M. Morandi, T. Malinski, and M.W. Radomski Br. J. Pharmacol. 146 2005 882 893
242. H.Z. Movat, W.J. Weiser, M.F. Glynn, and J.F. Mustard J. Cell Biol. 27 1965 531 543
243. C.F. Jones, R.A. Campbell, A.E. Brooks, S. Assemi, S. Tadjiki, G. Thiagarajan, C. Mulcock, A.S. Weyrich, B.D. Brooks, H. Ghandehari, and D.W. Grainger ACS Nano 6 2012 9900 9910
244. C.F. Jones, R.A. Campbell, Z. Franks, C.C. Gibson, G. Thiagarajan, A. Vieira-de-Abreu, S. Sukavaneshvar, S.F. Mohammad, D.Y. Li, H. Ghandehari, A.S. Weyrich, B.D. Brooks, and D.W. Grainger Mol. Pharm. 9 2012 1599 1611
245. K. Greish, G. Thiagarajan, H. Herd, R. Price, H. Bauer, D. Hubbard, A. Burckle, S. Sadekar, T. Yu, A. Anwar, A. Ray, and H. Ghandehari Nanotoxicology 6 2012 713 723
246. A.N. Ilinskaya, and M.A. Dobrovolskaia Nanomedicine (Lond) 8 2013 969 981
247. J. Park, D.H. Lim, H.J. Lim, T. Kwon, J.S. Choi, S. Jeong, I.H. Choi, and J. Cheon Chem. Commun. (Camb) 47 2011 4382 4384
248. D.-H. Lim, J. Jang, S. Kim, T. Kang, K. Lee, and I.-H. Choi Biomaterials 33 2012 4690 4699
249. J.D. Wilbourn, D.B. McGregor, C. Partensky, and J.M. Rice Environ. Health Perspect. 105 1997 756 759
250. J. Ovrevik, M. Refsnes, E. Namork, R. Becher, D. Sandnes, P.E. Schwarze, and M. Lag Toxicology 227 2006 105 116
251. A.G. Lenz, F. Krombach, and K.L. Maier Free Radic. Biol. Med. 12 1992 1 10
252. M.T. Kleinman, J.A. Araujo, A. Nel, C. Sioutas, A. Campbell, P.Q. Cong, H. Li, and S.C. Bondy Toxicol. Lett. 178 2008 127 130
253. Y. Lacasse, S. Martin, D. Gagne, and L. Lakhal Cancer Causes Control 20 2009 925 933
254. E. Hnizdo, and V. Vallyathan Occup. Environ. Med. 60 2003 237 243
255. P. Cocco, M. Dosemeci, and C. Rice Med. Lav. 98 2007 3 17
256. R.K. Iler The Chemistry of Silica 1979 John Wiley and Sons Inc. New York
257. R.P. Garay, R. El-Gewely, J.K. Armstrong, G. Garratty, and P. Richette Expert Opin. Drug Deliv. 9 2012 1319 1323
258. H. Schellekens, W.E. Hennink, and V. Brinks Pharm. Res. 30 2013 1729 1734
259. P. Burger, P. Hilarius-Stokman, D. de Korte, T.K. van den Berg, and R. van Bruggen Blood 119 2012 5512 5521
260. K. Weiskopf, A.M. Ring, C.C.M. Ho, J.-P. Volkmer, A.M. Levin, A.K. Volkmer, E. Özkan, N.B. Fernhoff, M. van de Rijn, and I.L. Weissman Science 341 2013 88 91
261. C.A. Smith, S. Wiley, A. Kaykas, P. Probst, in, Google Patents, United States, 2007.
262. P.L. Rodriguez, T. Harada, D.A. Christian, D.A. Pantano, R.K. Tsai, and D.E. Discher Science 339 2013 971 975
263. M. Niu, Y.W. Naguib, A.M. Aldayel, Y.C. Shi, S.D. Hursting, M.A. Hersh, and Z. Cui Mol. Pharm. 11 2014 4425 4436
264. S. Zhu, M. Niu, H. O'Mary, and Z. Cui Mol. Pharm. 10 2013 3525 3530
265. N. Duzgunes, E. Pretzer, S. Simoes, V. Slepushkin, K. Konopka, D. Flasher, and M.C. de Lima Mol. Membr. Biol. 16 1999 111 118
266. T. Dutta, M. Garg, and N.K. Jain Eur. J. Pharm. Sci. 34 2008 181 189
267. V. Schafer, H. von Briesen, R. Andreesen, A.M. Steffan, C. Royer, S. Troster, J. Kreuter, and H. Rubsamen-Waigmann Pharm. Res. 9 1992 541 546
268. P. Couvreur, E. Fattal, and A. Andremont Pharm. Res. 8 1991 1079 1086
269. D.L. Clemens, B.Y. Lee, M. Xue, C.R. Thomas, H. Meng, D. Ferris, A.E. Nel, J.I. Zink, and M.A. Horwitz Antimicrob. Agents Chemother. 56 2012 2535 2545
270. G. Escobar, B. Gentner, L. Naldini, and R. Mazzieri Oncoimmunology 3 2014 e28696
271. E.V. Batrakova, H.E. Gendelman, and A.V. Kabanov Expert Opin. Drug Deliv. 8 2011 415 433
272. M.S. Shive, and J.M. Anderson Adv. Drug Deliv. Rev. 28 1997 5 24
273. R.J. Basaraba Tuberculosis (Edinb) 88 1 Suppl 2008 S35 S47