Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy

ACS Nano

Volumn 7, Issue 12, 2013, Pages 10671-10680

  Valencia, Pedro M ^a   Pridgen, Eric M ^a   Rhee, Minsoung ^a,b   Langer, Robert ^a,c   Farokhzad, Omid C ^b,c   Karnik, Rohit ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

microfluidics; mixing; nanomedicine; nanoparticle; rapid synthesis

Indexed keywords

CLINICAL TRANSLATION; COMBINATORIAL SYNTHESIS; MICROFLUIDIC PLATFORMS; PHARMACOKINETIC STUDIES; POLY LACTIC-CO-GLYCOLIC ACID; PROSTATE CANCER CELLS; RAPID SYNTHESIS; TARGETED NANOPARTICLE;

CHELATION; LIGANDS; MACROPHAGES; MAMMALS; MEDICAL NANOTECHNOLOGY; MICROFLUIDICS; MIXING; NANOPARTICLES; OPTIMIZATION; POLYETHYLENE GLYCOLS;

SYNTHESIS (CHEMICAL);

DRUG CARRIER; LIGAND; MACROGOL DERIVATIVE; NANOPARTICLE; POLY(LACTIC GLYCOLIC ACID) POLY(ETHYLENEGLYCOL) COPOLYMER; POLY(LACTIC-GLYCOLIC ACID)-POLY(ETHYLENEGLYCOL) COPOLYMER; POLYGLACTIN; POLYMER;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG EFFECT; HUMAN; MACROPHAGE; MEDICINAL CHEMISTRY; MICROFLUIDICS; MOUSE; NANOMEDICINE; NEOPLASM; SURFACE PROPERTY; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG CARRIERS; HUMANS; LIGANDS; MACROPHAGES; MICE; MICROFLUIDICS; NANOMEDICINE; NANOPARTICLES; NEOPLASMS; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; POLYMERS; SURFACE PROPERTIES;

EID: 84891362991     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403370e     Document Type: Article

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