-
1
-
-
84880313916
-
Evolving importance of kidney disease: from subspecialty to global health burden
-
K.U. Eckardt, and et al. Evolving importance of kidney disease: from subspecialty to global health burden Lancet 382 2013 158 169
-
(2013)
Lancet
, vol.382
, pp. 158-169
-
-
Eckardt, K.U.1
-
2
-
-
2442680120
-
Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL
-
D. de Zeeuw, and et al. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL Kidney Int. 65 2004 2309 2320
-
(2004)
Kidney Int.
, vol.65
, pp. 2309-2320
-
-
De Zeeuw, D.1
-
3
-
-
82255175640
-
What makes a good drug target?
-
I. Gashaw, and et al. What makes a good drug target? Drug Discov. Today 16 2011 1037 1043
-
(2011)
Drug Discov. Today
, vol.16
, pp. 1037-1043
-
-
Gashaw, I.1
-
4
-
-
33645403170
-
Hereditary proteinuria syndromes and mechanisms of proteinuria
-
K. Tryggvason, and et al. Hereditary proteinuria syndromes and mechanisms of proteinuria N. Engl. J. Med. 354 2006 1387 1401
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1387-1401
-
-
Tryggvason, K.1
-
5
-
-
84884689933
-
Novel drugs and intervention strategies for the treatment of chronic kidney disease
-
H.J. Lambers Heerspink, and D. de Zeeuw Novel drugs and intervention strategies for the treatment of chronic kidney disease Br. J. Clin. Pharmacol. 76 2013 536 550
-
(2013)
Br. J. Clin. Pharmacol.
, vol.76
, pp. 536-550
-
-
Lambers Heerspink, H.J.1
De Zeeuw, D.2
-
6
-
-
0037207471
-
Cell biology of the glomerular podocyte
-
H. Pavenstadt, and et al. Cell biology of the glomerular podocyte Physiol. Rev. 83 2003 253 307
-
(2003)
Physiol. Rev.
, vol.83
, pp. 253-307
-
-
Pavenstadt, H.1
-
7
-
-
84923186960
-
Causes and pathogenesis of focal segmental glomerulosclerosis
-
A.B. Fogo Causes and pathogenesis of focal segmental glomerulosclerosis Nat. Rev. Nephrol. 11 2014 76 87
-
(2014)
Nat. Rev. Nephrol.
, vol.11
, pp. 76-87
-
-
Fogo, A.B.1
-
8
-
-
34250006557
-
The spectrum of podocytopathies: a unifying view of glomerular diseases
-
R.C. Wiggins The spectrum of podocytopathies: a unifying view of glomerular diseases Kidney Int. 71 2007 1205 1214
-
(2007)
Kidney Int.
, vol.71
, pp. 1205-1214
-
-
Wiggins, R.C.1
-
9
-
-
29144490392
-
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
-
B.L. Wharram, and et al. Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene J. Am. Soc. Nephrol. 16 2005 2941 2952
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 2941-2952
-
-
Wharram, B.L.1
-
10
-
-
0031029379
-
Podocyte loss and progressive glomerular injury in type II diabetes
-
M.E. Pagtalunan, and et al. Podocyte loss and progressive glomerular injury in type II diabetes J. Clin. Invest. 99 1997 342 348
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 342-348
-
-
Pagtalunan, M.E.1
-
11
-
-
84455208254
-
The podocyte as a target for therapies - new and old
-
P.W. Mathieson The podocyte as a target for therapies - new and old Nat. Rev. Nephrol. 8 2012 52 56
-
(2012)
Nat. Rev. Nephrol.
, vol.8
, pp. 52-56
-
-
Mathieson, P.W.1
-
12
-
-
84878619489
-
The role of the podocyte in albumin filtration
-
P.T. Brinkkoetter, and et al. The role of the podocyte in albumin filtration Nat. Rev. Nephrol. 9 2013 328 336
-
(2013)
Nat. Rev. Nephrol.
, vol.9
, pp. 328-336
-
-
Brinkkoetter, P.T.1
-
13
-
-
77950517549
-
Toward the development of podocyte-specific drugs
-
J. Reiser, and et al. Toward the development of podocyte-specific drugs Kidney Int. 77 2010 662 668
-
(2010)
Kidney Int.
, vol.77
, pp. 662-668
-
-
Reiser, J.1
-
14
-
-
84907188863
-
Role of podocyte B7-1 in diabetic nephropathy
-
P. Fiorina, and et al. Role of podocyte B7-1 in diabetic nephropathy J. Am. Soc. Nephrol. 25 2014 1415 1429
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 1415-1429
-
-
Fiorina, P.1
-
15
-
-
85047691168
-
Induction of B7-1 in podocytes is associated with nephrotic syndrome
-
J. Reiser, and et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome J. Clin. Invest. 113 2004 1390 1397
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1390-1397
-
-
Reiser, J.1
-
16
-
-
84890409760
-
Abatacept in B7-1-positive proteinuric kidney disease
-
C.C. Yu, and et al. Abatacept in B7-1-positive proteinuric kidney disease N. Engl. J. Med. 369 2013 2416 2423
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 2416-2423
-
-
Yu, C.C.1
-
17
-
-
84897001037
-
Abatacept in B7-1-positive proteinuric kidney disease
-
A. Benigni, and et al. Abatacept in B7-1-positive proteinuric kidney disease N. Engl. J. Med. 370 2014 1261 1263
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 1261-1263
-
-
Benigni, A.1
-
18
-
-
0037093320
-
Podocyte is the major culprit accounting for the progression of chronic renal disease
-
W. Kriz Podocyte is the major culprit accounting for the progression of chronic renal disease Microsc. Res. Tech. 57 2002 189 195
-
(2002)
Microsc. Res. Tech.
, vol.57
, pp. 189-195
-
-
Kriz, W.1
-
19
-
-
84874040904
-
The podocyte's response to stress: the enigma of foot process effacement
-
W. Kriz, and et al. The podocyte's response to stress: the enigma of foot process effacement Am. J. Physiol. Renal. Physiol. 304 2013 F333 F347
-
(2013)
Am. J. Physiol. Renal. Physiol.
, vol.304
, pp. F333-F347
-
-
Kriz, W.1
-
20
-
-
84455169599
-
The podocyte cytoskeleton - key to a functioning glomerulus in health and disease
-
G.I. Welsh, and M.A. Saleem The podocyte cytoskeleton - key to a functioning glomerulus in health and disease Nat. Rev. Nephrol. 8 2012 14 21
-
(2012)
Nat. Rev. Nephrol.
, vol.8
, pp. 14-21
-
-
Welsh, G.I.1
Saleem, M.A.2
-
21
-
-
84863533629
-
Knocking out podocyte rho GTPases: and the winner is
-
M.A. Lal, and K. Tryggvason Knocking out podocyte rho GTPases: and the winner is J. Am. Soc. Nephrol. 23 2012 1128 1129
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 1128-1129
-
-
Lal, M.A.1
Tryggvason, K.2
-
22
-
-
84886014027
-
Role of Rho-GTPases and their regulatory proteins in glomerular podocyte function
-
F. Mouawad, and et al. Role of Rho-GTPases and their regulatory proteins in glomerular podocyte function Can. J. Physiol. Pharmacol. 91 2013 773 782
-
(2013)
Can. J. Physiol. Pharmacol.
, vol.91
, pp. 773-782
-
-
Mouawad, F.1
-
23
-
-
80053410497
-
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
-
S. Akilesh, and et al. Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis J. Clin. Invest. 121 2011 4127 4137
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4127-4137
-
-
Akilesh, S.1
-
24
-
-
33744969296
-
Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling
-
K. Asanuma, and et al. Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling Nat. Cell Biol. 8 2006 485 491
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 485-491
-
-
Asanuma, K.1
-
25
-
-
84924032998
-
Rhophilin-1 is a key regulator of the podocyte cytoskeleton and is essential for glomerular filtration
-
M.A. Lal, and et al. Rhophilin-1 is a key regulator of the podocyte cytoskeleton and is essential for glomerular filtration J. Am. Soc. Nephrol. 26 2015 647 662
-
(2015)
J. Am. Soc. Nephrol.
, vol.26
, pp. 647-662
-
-
Lal, M.A.1
-
26
-
-
84882245010
-
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks
-
M. Boerries, and et al. Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks Kidney Int. 83 2013 1052 1064
-
(2013)
Kidney Int.
, vol.83
, pp. 1052-1064
-
-
Boerries, M.1
-
27
-
-
80052527646
-
Defining the molecular character of the developing and adult kidney podocyte
-
E.W. Brunskill, and et al. Defining the molecular character of the developing and adult kidney podocyte PLoS ONE 6 2011 e24640
-
(2011)
PLoS ONE
, vol.6
-
-
Brunskill, E.W.1
-
28
-
-
33644863418
-
Large-scale identification of genes implicated in kidney glomerulus development and function
-
M. Takemoto, and et al. Large-scale identification of genes implicated in kidney glomerulus development and function EMBO J. 25 2006 1160 1174
-
(2006)
EMBO J.
, vol.25
, pp. 1160-1174
-
-
Takemoto, M.1
-
29
-
-
84887415137
-
Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes
-
K. Hasegawa, and et al. Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes Nat. Med. 19 2013 1496 1504
-
(2013)
Nat. Med.
, vol.19
, pp. 1496-1504
-
-
Hasegawa, K.1
-
30
-
-
84902166317
-
KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria
-
K. Hayashi, and et al. KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria J. Clin. Invest. 124 2014 2523 2537
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 2523-2537
-
-
Hayashi, K.1
-
31
-
-
84907199746
-
Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier
-
M.M. Rinschen, and et al. Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier J. Am. Soc. Nephrol. 25 2014 1509 1522
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 1509-1522
-
-
Rinschen, M.M.1
-
32
-
-
84884412556
-
Defining cell-type specificity at the transcriptional level in human disease
-
W. Ju, and et al. Defining cell-type specificity at the transcriptional level in human disease Genome Res. 23 2013 1862 1873
-
(2013)
Genome Res.
, vol.23
, pp. 1862-1873
-
-
Ju, W.1
-
33
-
-
34347357580
-
Podocytes in culture: past, present, and future
-
S.J. Shankland, and et al. Podocytes in culture: past, present, and future Kidney Int. 72 2007 26 36
-
(2007)
Kidney Int.
, vol.72
, pp. 26-36
-
-
Shankland, S.J.1
-
34
-
-
0036189998
-
A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression
-
M.A. Saleem, and et al. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression J. Am. Soc. Nephrol. 13 2002 630 638
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 630-638
-
-
Saleem, M.A.1
-
35
-
-
84938310769
-
A podocyte-based automated screening assay identifies protective small molecules
-
pii:ASN.2014090859
-
H.W. Lee, and et al. A podocyte-based automated screening assay identifies protective small molecules J. Am. Soc. Nephrol. 2015 pii:ASN.2014090859
-
(2015)
J. Am. Soc. Nephrol.
-
-
Lee, H.W.1
-
36
-
-
35348858911
-
Cell-based high-content screening of small-molecule libraries
-
K. Korn, and E. Krausz Cell-based high-content screening of small-molecule libraries Curr. Opin. Chem. Biol. 11 2007 503 510
-
(2007)
Curr. Opin. Chem. Biol.
, vol.11
, pp. 503-510
-
-
Korn, K.1
Krausz, E.2
-
37
-
-
84941766470
-
Enhanced glycogen synthase kinase-3beta activity mediates podocyte apoptosis under diabetic conditions
-
J. Paeng, and et al. Enhanced glycogen synthase kinase-3beta activity mediates podocyte apoptosis under diabetic conditions Apoptosis 19 2014 1678 1690
-
(2014)
Apoptosis
, vol.19
, pp. 1678-1690
-
-
Paeng, J.1
-
38
-
-
84922248283
-
Glycogen synthase kinase 3beta orchestrates microtubule remodeling in compensatory glomerular adaptation to podocyte depletion
-
W. Xu, and et al. Glycogen synthase kinase 3beta orchestrates microtubule remodeling in compensatory glomerular adaptation to podocyte depletion J. Biol. Chem. 290 2015 1348 1363
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 1348-1363
-
-
Xu, W.1
-
39
-
-
19944432043
-
Cellular targets of gefitinib
-
D. Brehmer, and et al. Cellular targets of gefitinib Cancer Res. 65 2005 379 382
-
(2005)
Cancer Res.
, vol.65
, pp. 379-382
-
-
Brehmer, D.1
-
40
-
-
79960983894
-
Drug target deconvolution by chemical proteomics
-
M. Raida Drug target deconvolution by chemical proteomics Curr. Opin. Chem. Biol. 15 2011 570 575
-
(2011)
Curr. Opin. Chem. Biol.
, vol.15
, pp. 570-575
-
-
Raida, M.1
-
41
-
-
84879696354
-
PodNet, a protein-protein interaction network of the podocyte
-
G. Warsow, and et al. PodNet, a protein-protein interaction network of the podocyte Kidney Int. 84 2013 104 115
-
(2013)
Kidney Int.
, vol.84
, pp. 104-115
-
-
Warsow, G.1
-
42
-
-
84901426975
-
Two-photon microscopy reveals stationary podocytes in living zebrafish larvae
-
N. Endlich, and et al. Two-photon microscopy reveals stationary podocytes in living zebrafish larvae J. Am. Soc. Nephrol. 25 2014 681 686
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 681-686
-
-
Endlich, N.1
-
43
-
-
84889879902
-
Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags
-
M.J. Hackl, and et al. Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags Nat. Med. 19 2013 1661 1666
-
(2013)
Nat. Med.
, vol.19
, pp. 1661-1666
-
-
Hackl, M.J.1
-
44
-
-
84893298586
-
In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye
-
A.D. Kistler, and et al. In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye Sci. Rep. 4 2014 3872
-
(2014)
Sci. Rep.
, vol.4
, pp. 3872
-
-
Kistler, A.D.1
-
45
-
-
58249123367
-
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm
-
H. Weavers, and et al. The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm Nature 457 2009 322 326
-
(2009)
Nature
, vol.457
, pp. 322-326
-
-
Weavers, H.1
-
46
-
-
84873357381
-
An in vivo functional analysis system for renal gene discovery in Drosophila pericardial nephrocytes
-
F. Zhang, and et al. An in vivo functional analysis system for renal gene discovery in Drosophila pericardial nephrocytes J. Am. Soc. Nephrol. 24 2013 191 197
-
(2013)
J. Am. Soc. Nephrol.
, vol.24
, pp. 191-197
-
-
Zhang, F.1
-
47
-
-
79958844058
-
Zebrafish: a model system for the study of vertebrate renal development, function, and pathophysiology
-
L. Ebarasi, and et al. Zebrafish: a model system for the study of vertebrate renal development, function, and pathophysiology Curr. Opin. Nephrol. Hypertens. 20 2011 416 424
-
(2011)
Curr. Opin. Nephrol. Hypertens.
, vol.20
, pp. 416-424
-
-
Ebarasi, L.1
-
48
-
-
84861799316
-
Inducible podocyte injury and proteinuria in transgenic zebrafish
-
W. Zhou, and F. Hildebrandt Inducible podocyte injury and proteinuria in transgenic zebrafish J. Am. Soc. Nephrol. 23 2012 1039 1047
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 1039-1047
-
-
Zhou, W.1
Hildebrandt, F.2
-
50
-
-
77954038080
-
Reconstituting organ-level lung functions on a chip
-
D. Huh, and et al. Reconstituting organ-level lung functions on a chip Science 328 2010 1662 1668
-
(2010)
Science
, vol.328
, pp. 1662-1668
-
-
Huh, D.1
-
51
-
-
84877624830
-
Regeneration and experimental orthotopic transplantation of a bioengineered kidney
-
J.J. Song, and et al. Regeneration and experimental orthotopic transplantation of a bioengineered kidney Nat. Med. 19 2013 646 651
-
(2013)
Nat. Med.
, vol.19
, pp. 646-651
-
-
Song, J.J.1
-
52
-
-
38949210805
-
Podocytes use FcRn to clear IgG from the glomerular basement membrane
-
S. Akilesh, and et al. Podocytes use FcRn to clear IgG from the glomerular basement membrane Proc. Natl. Acad. Sci. U. S. A. 105 2008 967 972
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 967-972
-
-
Akilesh, S.1
-
53
-
-
77955590203
-
Establishment of protein delivery systems targeting podocytes
-
W.C. Chiang, and et al. Establishment of protein delivery systems targeting podocytes PLoS ONE 5 2010 e11837
-
(2010)
PLoS ONE
, vol.5
-
-
Chiang, W.C.1
-
54
-
-
77949756180
-
Novel siRNA delivery system to target podocytes in vivo
-
P.V. Hauser, and et al. Novel siRNA delivery system to target podocytes in vivo PLoS ONE 5 2010 e9463
-
(2010)
PLoS ONE
, vol.5
-
-
Hauser, P.V.1
-
55
-
-
78649448612
-
Drug targeting to the kidney: advances in the active targeting of therapeutics to proximal tubular cells
-
M.E. Dolman, and et al. Drug targeting to the kidney: advances in the active targeting of therapeutics to proximal tubular cells Adv. Drug Deliv. Rev. 62 2010 1344 1357
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 1344-1357
-
-
Dolman, M.E.1
-
56
-
-
0037498439
-
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
-
H.Y. Lan, and et al. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model J. Am. Soc. Nephrol. 14 2003 1535 1548
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1535-1548
-
-
Lan, H.Y.1
-
57
-
-
84921798210
-
AKI after conditional and kidney-specific knockdown of stanniocalcin-1
-
L. Huang, and et al. AKI after conditional and kidney-specific knockdown of stanniocalcin-1 J. Am. Soc. Nephrol. 25 2014 2303 2315
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 2303-2315
-
-
Huang, L.1
-
58
-
-
84901689853
-
Therapeutic approaches to diabetic nephropathy - beyond the RAS
-
B. Fernandez-Fernandez, and et al. Therapeutic approaches to diabetic nephropathy - beyond the RAS Nat. Rev. Nephrol. 10 2014 325 346
-
(2014)
Nat. Rev. Nephrol.
, vol.10
, pp. 325-346
-
-
Fernandez-Fernandez, B.1
|