Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening

Trends in Biotechnology

Volumn 34, Issue 2, 2016, Pages 156-170

  Wilmer, Martijn J ^a   Ng, Chee Ping ^b   Lanz, Henriëtte L ^b   Vulto, Paul ^b   Suter Dick, Laura ^c   Masereeuw, Rosalinde ^d  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MIMETAS BV   (Netherlands)

^c UNIVERSITY OF APPLIED SCIENCES AND ARTS NORTHWESTERN SWITZERLAND   (Switzerland)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Drug screening; High throughput screening; Kidney; Microfluidics; Nephrotoxicity; Organ on a chip

Indexed keywords

BIOMARKERS; EXTRAPOLATION; MICROFLUIDICS; MICROPROCESSOR CHIPS; PHYSIOLOGICAL MODELS; PHYSIOLOGY; THROUGHPUT;

DRUG SCREENING; HIGH THROUGHPUT SCREENING; KIDNEY; NEPHROTOXICITY; ORGAN-ON-A-CHIP;

DRUG INTERACTIONS;

HIGH THROUGHPUT SCREENING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; KIDNEY ON A CHIP TECHNOLOGY; KIDNEY PROXIMAL TUBULE; MICROFLUIDICS; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCREENING TEST; TECHNOLOGY; UROLOGICAL PROCEDURE; ACUTE KIDNEY FAILURE; BIOLOGICAL MODEL; CHEMICALLY INDUCED; DRUG EFFECTS; KIDNEY; MICROFLUIDIC ANALYSIS; ORGAN CULTURE TECHNIQUE; PRECLINICAL STUDY; PROCEDURES;

ACUTE KIDNEY INJURY; DRUG EVALUATION, PRECLINICAL; HUMANS; KIDNEY; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; ORGAN CULTURE TECHNIQUES;

EID: 84960177173     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2015.11.001     Document Type: Review

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