Shaping cancer nanomedicine: The effect of particle shape on the in vivo journey of nanoparticles

Nanomedicine

Volumn 9, Issue 1, 2014, Pages 121-134

  Toy, Randall ^a,b,c   Peiris, Pubudu M ^a,b,c   Ghaghada, Ketan B ^d,e   Karathanasis, Efstathios ^a,b,c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d TEXAS CHILDREN S HOSPITAL   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

biodistribution; cancer; margination; nanomedicine; nanoparticle shape; phagocytosis; targeting avidity; transport of nanoparticle

Indexed keywords

CELL SURFACE RECEPTOR; CYTOTOXIC AGENT; DOXORUBICIN; GOLD NANOPARTICLE; LIPOSOME; NANOCARRIER; NANOPARTICLE; NANOROD; NANOSPHERE; VITRONECTIN RECEPTOR;

ANTINEOPLASTIC ACTIVITY; BIOLOGICAL PHENOMENA AND FUNCTIONS CONCERNING THE ENTIRE ORGANISM; BLOOD FLOW; BLOOD FLOW VELOCITY; CANCER LOCALIZATION; CANCER MORTALITY; CANCER THERAPY; CIRCULATION; DRUG RELEASE; ENDOCYTOSIS; ERYTHROCYTE; GOOD MANUFACTURING PRACTICE; HEMODYNAMICS; HUMAN; IN VIVO STUDY; INTERNALIZATION; KIDNEY CLEARANCE; LEUKOCYTE; LIPID RAFT; MACROPHAGE; MICROCIRCULATION; MICROMETASTASIS; NANOFABRICATION; NANOMEDICINE; NONHUMAN; PARTICLE SIZE; PHYSICAL PHENOMENA; PLASMA HALF LIFE; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM; REVIEW; SHEAR RATE; TUMOR BLOOD FLOW; TUMOR VASCULARIZATION;

HUMANS; NANOMEDICINE; NANOPARTICLES; NEOPLASMS; TISSUE DISTRIBUTION;

EID: 84896504632     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.191     Document Type: Review

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