-
1
-
-
49649094763
-
Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment
-
Abboud-Jarrous G, Atzmon R, Peretz T, Palermo C, Gadea BB, Joyce JA, Vlodavsky I (2008) Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment. J Biol Chem 283:18167-18176
-
(2008)
J Biol Chem
, vol.283
, pp. 18167-18176
-
-
Abboud-Jarrous, G.1
Atzmon, R.2
Peretz, T.3
Palermo, C.4
Gadea, B.B.5
Joyce, J.A.6
Vlodavsky, I.7
-
2
-
-
33748055761
-
Analysis of host-And tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer
-
Acuff HB, Sinnamon M, Fingleton B, Boone B, Levy SE, Chen X, Pozzi A, Carbone DP, Schwartz DR, Moin K, Sloane BF, Matrisian LM (2006) Analysis of host-And tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer. Cancer Res 66:7968-7975
-
(2006)
Cancer Res
, vol.66
, pp. 7968-7975
-
-
Acuff, H.B.1
Sinnamon, M.2
Fingleton, B.3
Boone, B.4
Levy, S.E.5
Chen, X.6
Pozzi, A.7
Carbone, D.P.8
Schwartz, D.R.9
Moin, K.10
Sloane, B.F.11
Matrisian, L.M.12
-
3
-
-
2342667387
-
The development of proteasome inhibitors as anticancer drugs
-
Adams J (2004) The development of proteasome inhibitors as anticancer drugs. Cancer Cell 5:417-421
-
(2004)
Cancer Cell
, vol.5
, pp. 417-421
-
-
Adams, J.1
-
4
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J (2004) The proteasome: a suitable antineoplastic target. Nat Rev Cancer 4:349-360
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
5
-
-
33645869560
-
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
-
Agrawal S, Anderson P, Durbeej M, van Rooijen N, Ivars F, Opdenakker G, Sorokin LM (2006) Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. J Exp Med 203:1007-1019
-
(2006)
J Exp Med
, vol.203
, pp. 1007-1019
-
-
Agrawal, S.1
Anderson, P.2
Durbeej, M.3
Van Rooijen, N.4
Ivars, F.5
Opdenakker, G.6
Sorokin, L.M.7
-
6
-
-
39849100541
-
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: Role of bone marrow-derived myelomonocytic cells
-
Ahn GO, Brown JM (2008) Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 13:193-205
-
(2008)
Cancer Cell
, vol.13
, pp. 193-205
-
-
Ahn, G.O.1
Brown, J.M.2
-
7
-
-
84863378692
-
Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe
-
Akers WJ, Xu B, Lee H, Sudlow GP, Fields GB, Achilefu S, Edwards WB (2012) Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe. Bioconjug Chem 23:656-663
-
(2012)
Bioconjug Chem
, vol.23
, pp. 656-663
-
-
Akers, W.J.1
Xu, B.2
Lee, H.3
Sudlow, G.P.4
Fields, G.B.5
Achilefu, S.6
Edwards, W.B.7
-
8
-
-
34250828565
-
Colonic adenocarcinomas: Near-infrared microcatheter imaging of smart probes for early detection-study in mice
-
Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U (2007) Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection-study in mice. Radiology 244:232-238
-
(2007)
Radiology
, vol.244
, pp. 232-238
-
-
Alencar, H.1
Funovics, M.A.2
Figueiredo, J.3
Sawaya, H.4
Weissleder, R.5
Mahmood, U.6
-
9
-
-
0043284287
-
Stromal cell involvement in cancer
-
Springer, Berlin
-
Almholt K, JohnsenM(2003) Stromal cell involvement in cancer. In: Molecular staging of cancer, vol 162. Springer, Berlin, pp 31-42
-
(2003)
Molecular Staging of Cancer
, vol.162
, pp. 31-42
-
-
Almholt, K.1
Johnsen, M.2
-
10
-
-
0042804870
-
Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice
-
Almholt K, Nielsen BS, Frandsen TL, Brunner N, Dano K, Johnsen M (2003) Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice. Oncogene 22:4389-4397
-
(2003)
Oncogene
, vol.22
, pp. 4389-4397
-
-
Almholt, K.1
Nielsen, B.S.2
Frandsen, T.L.3
Brunner, N.4
Dano, K.5
Johnsen, M.6
-
11
-
-
33947122115
-
Extracellular proteolysis in transgenic mouse models of breast cancer
-
Almholt K, Green KA, Juncker-Jensen A, Nielsen BS, Lund LR, Romer J (2007) Extracellular proteolysis in transgenic mouse models of breast cancer. J Mammary Gland Biol Neoplasia 12:83-97
-
(2007)
J Mammary Gland Biol Neoplasia
, vol.12
, pp. 83-97
-
-
Almholt, K.1
Green, K.A.2
Juncker-Jensen, A.3
Nielsen, B.S.4
Lund, L.R.5
Romer, J.6
-
12
-
-
0037328613
-
NF-kappaB activation in cancer: A challenge for ubiquitination-And proteasome-based therapeutic approach
-
Amit S, Ben-Neriah Y (2003) NF-kappaB activation in cancer: a challenge for ubiquitination-And proteasome-based therapeutic approach. Semin Cancer Biol 13:15-28
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 15-28
-
-
Amit, S.1
Ben-Neriah, Y.2
-
13
-
-
0032429122
-
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
-
An B, Goldfarb RH, Siman R, Dou QP.
-
An B, Goldfarb RH, Siman R, Dou QP (1998) Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ 5:1062-1075
-
(1998)
Cell Death Differ
, vol.5
, pp. 1062-1075
-
-
-
15
-
-
70450253102
-
A disintegrin-like and metalloprotease (reprolysin-Type) with thrombospondin type 1 motif (ADAMTS) superfamily: Functions and mechanisms
-
Apte SS (2009) A disintegrin-like and metalloprotease (reprolysin-Type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms. J Biol Chem 284:31493-31497
-
(2009)
J Biol Chem
, vol.284
, pp. 31493-31497
-
-
Apte, S.S.1
-
16
-
-
70350029581
-
Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway
-
Ardi VC, Van den Steen PE, Opdenakker G, Schweighofer B, Deryugina EI, Quigley JP (2009) Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. J Biol Chem 284:25854-25866
-
(2009)
J Biol Chem
, vol.284
, pp. 25854-25866
-
-
Ardi, V.C.1
Van Den Steen, P.E.2
Opdenakker, G.3
Schweighofer, B.4
Deryugina, E.I.5
Quigley, J.P.6
-
17
-
-
78149357484
-
Proteomic techniques and activity-based probes for the system-wide study of proteolysis
-
Aufdem Keller U, Schilling O (2010) Proteomic techniques and activity-based probes for the system-wide study of proteolysis. Biochimie 92:1705-1714
-
(2010)
Biochimie
, vol.92
, pp. 1705-1714
-
-
Aufdem Keller, U.1
Schilling, O.2
-
18
-
-
0034653998
-
C-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram F, von der Lehr N, Cetinkaya C, Larsson LG (2000) c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 95:2104-2110
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
Von Der Lehr, N.2
Cetinkaya, C.3
Larsson, L.G.4
-
19
-
-
0242361314
-
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
-
Balbin M, Fueyo A, Tester AM, Pendas AM, Pitiot AS, Astudillo A, Overall CM, Shapiro SD, Lopez-Otin C (2003) Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Nat Genet 35:252-257
-
(2003)
Nat Genet
, vol.35
, pp. 252-257
-
-
Balbin, M.1
Fueyo, A.2
Tester, A.M.3
Pendas, A.M.4
Pitiot, A.S.5
Astudillo, A.6
Overall, C.M.7
Shapiro, S.D.8
Lopez-Otin, C.9
-
20
-
-
76349124866
-
Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts
-
Barwick BG, Abramovitz M, Kodani M, Moreno CS, Nam R, Tang W, Bouzyk M, Seth A, Leyland-Jones B (2010) Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts. Br J Cancer 102:570-576
-
(2010)
Br J Cancer
, vol.102
, pp. 570-576
-
-
Barwick, B.G.1
Abramovitz, M.2
Kodani, M.3
Moreno, C.S.4
Nam, R.5
Tang, W.6
Bouzyk, M.7
Seth, A.8
Leyland-Jones, B.9
-
21
-
-
78649966606
-
Androgen-induced TMPRSS2 ERG fusion in nonmalignant prostate epithelial cells
-
Bastus NC, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver RTD, Berney DM, Lu Y-J (2010) Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells. Cancer Res 70:9544-9548
-
(2010)
Cancer Res
, vol.70
, pp. 9544-9548
-
-
Bastus, N.C.1
Boyd, L.K.2
Mao, X.3
Stankiewicz, E.4
Kudahetti, S.C.5
Oliver, R.T.D.6
Berney, D.M.7
Lu, Y.-J.8
-
22
-
-
34547640302
-
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer
-
Bell-McGuinn KM, Garfall AL, Bogyo M, Hanahan D, Joyce JA (2007) Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer. Cancer Res 67:7378-7385
-
(2007)
Cancer Res
, vol.67
, pp. 7378-7385
-
-
Bell-Mcguinn, K.M.1
Garfall, A.L.2
Bogyo, M.3
Hanahan, D.4
Joyce, J.A.5
-
23
-
-
84858150882
-
Protective role of cathepsin L in mouse skin carcinogenesis
-
Benavides F, Perez C, Blando J, Contreras O, Shen J, Coussens LM, Fischer SM, Kusewitt DF, Digiovanni J, Conti CJ (2012) Protective role of cathepsin L in mouse skin carcinogenesis. Mol Carcinog. 51:352-361
-
(2012)
Mol Carcinog
, vol.51
, pp. 352-361
-
-
Benavides, F.1
Perez, C.2
Blando, J.3
Contreras, O.4
Shen, J.5
Coussens, L.M.6
Fischer, S.M.7
Kusewitt, D.F.8
Digiovanni, J.9
Conti, C.J.10
-
24
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah Y, Karin M (2011) Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol 12:715-723
-
(2011)
Nat Immunol
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
25
-
-
0000391746
-
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
-
Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2:737-744
-
(2000)
Nat Cell Biol
, vol.2
, pp. 737-744
-
-
Bergers, G.1
Brekken, R.2
McMahon, G.3
Vu, T.H.4
Itoh, T.5
Tamaki, K.6
Tanzawa, K.7
Thorpe, P.8
Itohara, S.9
Werb, Z.10
Hanahan, D.11
-
26
-
-
77956630130
-
Loss of the Matriptase Inhibitor HAI-2 during Prostate Cancer Progression
-
Bergum C, List K (2010) Loss of the Matriptase Inhibitor HAI-2 During Prostate Cancer Progression. Prostate 70:1422-1428
-
(2010)
Prostate
, vol.70
, pp. 1422-1428
-
-
Bergum, C.1
List, K.2
-
27
-
-
77958575793
-
Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: Characterization of cytokine response and migration capability after Helicobacter pylori infection
-
Bernhardt A, Kuester D, Roessner A, Reinheckel T, Krueger S (2010) Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after Helicobacter pylori infection. J Biol Chem 285:33691-33700
-
(2010)
J Biol Chem
, vol.285
, pp. 33691-33700
-
-
Bernhardt, A.1
Kuester, D.2
Roessner, A.3
Reinheckel, T.4
Krueger, S.5
-
28
-
-
33645057441
-
Matrix metalloproteinases play an active role in Wnt1-induced mammary tumorigenesis
-
Blavier L, Lazaryev A, Dorey F, Shackleford GM, DeClerck YA (2006) Matrix metalloproteinases play an active role in Wnt1-induced mammary tumorigenesis. Cancer Res 66:2691-2699
-
(2006)
Cancer Res
, vol.66
, pp. 2691-2699
-
-
Blavier, L.1
Lazaryev, A.2
Dorey, F.3
Shackleford, G.M.4
Declerck, Y.A.5
-
29
-
-
11244261160
-
ADAMs: Key components in EGFR signalling and development
-
Blobel CP (2005) ADAMs: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 6:32-43
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 32-43
-
-
Blobel, C.P.1
-
30
-
-
34548666006
-
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
-
Blum G, von Degenfeld G, Merchant MJ, Blau HM, BogyoM(2007) Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol 3:668-677
-
(2007)
Nat Chem Biol
, vol.3
, pp. 668-677
-
-
Blum, G.1
Von Degenfeld, G.2
Merchant, M.J.3
Blau, H.M.4
Bogyo, M.5
-
31
-
-
68149166462
-
Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity
-
Blum G, Weimer RM, Edgington LE, Adams W, Bogyo M (2009) Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity. PLoS One 4:e6374
-
(2009)
PLoS One
, vol.4
, pp. e6374
-
-
Blum, G.1
Weimer, R.M.2
Edgington, L.E.3
Adams, W.4
Bogyo, M.5
-
32
-
-
8144222388
-
The emerging roles of human tissue kallikreins in cancer
-
Borgono CA, Diamandis EP (2004) The emerging roles of human tissue kallikreins in cancer. Nat Rev Cancer 4:876-890
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 876-890
-
-
Borgono, C.A.1
Diamandis, E.P.2
-
33
-
-
3543150203
-
Human tissue kallikreins: Physiologic roles and applications in cancer
-
Borgono CA, Michael IP, Diamandis EP (2004) Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2:257-280
-
(2004)
Mol Cancer Res
, vol.2
, pp. 257-280
-
-
Borgono, C.A.1
Michael, I.P.2
Diamandis, E.P.3
-
34
-
-
70350536784
-
Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling
-
Bozkulak EC, Weinmaster G (2009) Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling. Mol Cell Biol 29:5679-5695
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5679-5695
-
-
Bozkulak, E.C.1
Weinmaster, G.2
-
35
-
-
77955625443
-
Matrix metalloproteinase 11/stromelysin-3 exerts both activator and repressor functions during the hematogenous metastatic process in mice
-
Brasse D, Mathelin C, Leroux K, Chenard MP, Blaise S, Stoll I, Tomasetto C, Rio MC (2010) Matrix metalloproteinase 11/stromelysin-3 exerts both activator and repressor functions during the hematogenous metastatic process in mice. Int J Cancer 127:1347-1355
-
(2010)
Int J Cancer
, vol.127
, pp. 1347-1355
-
-
Brasse, D.1
Mathelin, C.2
Leroux, K.3
Chenard, M.P.4
Blaise, S.5
Stoll, I.6
Tomasetto, C.7
Rio, M.C.8
-
36
-
-
0036516460
-
Matrix metalloproteinases: A tail of a frog that became a prince
-
Brinckerhoff CE, Matrisian LM (2002) Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol 3:207-214
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 207-214
-
-
Brinckerhoff, C.E.1
Matrisian, L.M.2
-
37
-
-
0010712792
-
Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
-
Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA (1998) Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 92:391-400
-
(1998)
Cell
, vol.92
, pp. 391-400
-
-
Brooks, P.C.1
Silletti, S.2
Von Schalscha, T.L.3
Friedlander, M.4
Cheresh, D.A.5
-
38
-
-
71849097154
-
Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis
-
Bruns AF, Herbert SP, Odell AF, Jopling HM, Hooper NM, Zachary IC, Walker JH, Ponnambalam S (2010) Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis. Traffic 11:161-174
-
(2010)
Traffic
, vol.11
, pp. 161-174
-
-
Bruns, A.F.1
Herbert, S.P.2
Odell, A.F.3
Jopling, H.M.4
Hooper, N.M.5
Zachary, I.C.6
Walker, J.H.7
Ponnambalam, S.8
-
39
-
-
7344248988
-
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice
-
Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmback K, Drew AF, Flick MJ, Witte DP, Dano K, Degen JL (1998) Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice. Oncogene 16:3097-3104
-
(1998)
Oncogene
, vol.16
, pp. 3097-3104
-
-
Bugge, T.H.1
Lund, L.R.2
Kombrinck, K.K.3
Nielsen, B.S.4
Holmback, K.5
Drew, A.F.6
Flick, M.J.7
Witte, D.P.8
Dano, K.9
Degen, J.L.10
-
40
-
-
34547684359
-
Matriptase-dependent cell surface proteolysis in epithelial development and pathogenesis
-
Bugge TH, List K, Szabo R (2007) Matriptase-dependent cell surface proteolysis in epithelial development and pathogenesis. Front Biosci 12:5060-5070
-
(2007)
Front Biosci
, vol.12
, pp. 5060-5070
-
-
Bugge, T.H.1
List, K.2
Szabo, R.3
-
41
-
-
69949118724
-
Type II transmembrane serine proteases
-
Bugge TH, Antalis TM, Wu Q (2009) Type II transmembrane serine proteases. J Biol Chem 284:23177-23181
-
(2009)
J Biol Chem
, vol.284
, pp. 23177-23181
-
-
Bugge, T.H.1
Antalis, T.M.2
Wu, Q.3
-
42
-
-
70349665206
-
Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis
-
Burden RE, Gormley JA, Jaquin TJ, Small DM, Quinn DJ, Hegarty SM, Ward C, Walker B, Johnston JA, Olwill SA, Scott CJ (2009) Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis. Clin Cancer Res 15:6042-6051
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6042-6051
-
-
Burden, R.E.1
Gormley, J.A.2
Jaquin, T.J.3
Small, D.M.4
Quinn, D.J.5
Hegarty, S.M.6
Ward, C.7
Walker, B.8
Johnston, J.A.9
Olwill, S.A.10
Scott, C.J.11
-
43
-
-
84855828185
-
Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas
-
Burden RE, Gormley JA, Kuehn D, Ward C, Kwok HF, Gazdoiu M, McClurg A, Jaquin TJ, Johnston JA, Scott CJ, Olwill SA (2012) Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas. Biochimie 94:487-493
-
(2012)
Biochimie
, vol.94
, pp. 487-493
-
-
Burden, R.E.1
Gormley, J.A.2
Kuehn, D.3
Ward, C.4
Kwok, H.F.5
Gazdoiu, M.6
McClurg, A.7
Jaquin, T.J.8
Johnston, J.A.9
Scott, C.J.10
Olwill, S.A.11
-
44
-
-
77953169923
-
ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells
-
Casal C, Torres-Collado AX, Plaza-Calonge Mdel C, Martino-Echarri E, Ramon YCS, Rojo F, Griffioen AW, Rodriguez-Manzaneque JC (2010) ADAMTS1 contributes to the acquisition of an endothelial-like phenotype in plastic tumor cells. Cancer Res 70:4676-4686
-
(2010)
Cancer Res
, vol.70
, pp. 4676-4686
-
-
Casal, C.1
Torres-Collado, A.X.2
Plaza-Calonge Mdel, C.3
Martino-Echarri, E.4
Ramon, Y.C.S.5
Rojo, F.6
Griffioen, A.W.7
Rodriguez-Manzaneque, J.C.8
-
45
-
-
34250312341
-
The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases
-
Cauwe B, Van den Steen PE, Opdenakker G (2007) The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases. Crit Rev Biochem Mol Biol 42:113-185
-
(2007)
Crit Rev Biochem Mol Biol
, vol.42
, pp. 113-185
-
-
Cauwe, B.1
Van Den Steen, P.E.2
Opdenakker, G.3
-
46
-
-
79951708401
-
Targeting proteasomes with natural occurring compounds in cancer treatment
-
Cecarini V, Cuccioloni M, Mozzicafreddo M, Bonfili L, Angeletti M, Eleuteri AM (2011) Targeting proteasomes with natural occurring compounds in cancer treatment. Curr Cancer Drug Targets 11:307-324
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 307-324
-
-
Cecarini, V.1
Cuccioloni, M.2
Mozzicafreddo, M.3
Bonfili, L.4
Angeletti, M.5
Eleuteri, A.M.6
-
47
-
-
1642300508
-
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment
-
Chantrain CF, Shimada H, Jodele S, Groshen S, Ye W, Shalinsky DR, Werb Z, Coussens LM, DeClerck YA (2004) Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment. Cancer Res 64:1675-1686
-
(2004)
Cancer Res
, vol.64
, pp. 1675-1686
-
-
Chantrain, C.F.1
Shimada, H.2
Jodele, S.3
Groshen, S.4
Ye, W.5
Shalinsky, D.R.6
Werb, Z.7
Coussens, L.M.8
Declerck, Y.A.9
-
48
-
-
0037320124
-
Matrix metalloproteinase inhibitors-An emphasis on gastrointestinal malignancies
-
Chau I, Rigg A, Cunningham D (2003) Matrix metalloproteinase inhibitors-An emphasis on gastrointestinal malignancies. Crit Rev Oncol Hematol 45:151-176
-
(2003)
Crit Rev Oncol Hematol
, vol.45
, pp. 151-176
-
-
Chau, I.1
Rigg, A.2
Cunningham, D.3
-
49
-
-
27644562277
-
A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
-
Chauhan D, Catley L, Li G, Podar K, Hideshima T, Velankar M, Mitsiades C, Mitsiades N, Yasui H, Letai A, Ovaa H, Berkers C, Nicholson B, Chao TH, Neuteboom ST, Richardson P, Palladino MA, Anderson KC (2005) A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell 8:407-419
-
(2005)
Cancer Cell
, vol.8
, pp. 407-419
-
-
Chauhan, D.1
Catley, L.2
Li, G.3
Podar, K.4
Hideshima, T.5
Velankar, M.6
Mitsiades, C.7
Mitsiades, N.8
Yasui, H.9
Letai, A.10
Ovaa, H.11
Berkers, C.12
Nicholson, B.13
Chao, T.H.14
Neuteboom, S.T.15
Richardson, P.16
Palladino, M.A.17
Anderson, K.C.18
-
50
-
-
0035877836
-
Prostasin is a glycosylphosphatidylinositol-Anchored active serine protease
-
Chen LM, Skinner ML, Kauffman SW, Chao J, Chao L, Thaler CD, Chai KX (2001) Prostasin is a glycosylphosphatidylinositol-Anchored active serine protease. J Biol Chem 276:21434-21442
-
(2001)
J Biol Chem
, vol.276
, pp. 21434-21442
-
-
Chen, L.M.1
Skinner, M.L.2
Kauffman, S.W.3
Chao, J.4
Chao, L.5
Thaler, C.D.6
Chai, K.X.7
-
51
-
-
1642326652
-
Regulation of prostasin expression and function in the prostate
-
Chen LM, Zhang XC, Chai KX (2004) Regulation of prostasin expression and function in the prostate. Prostate 59:1-12
-
(2004)
Prostate
, vol.59
, pp. 1-12
-
-
Chen, L.M.1
Zhang, X.C.2
Chai, K.X.3
-
52
-
-
20444480261
-
Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells
-
Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A (2005) Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells. Int J Cancer 116:52-61
-
(2005)
Int J Cancer
, vol.116
, pp. 52-61
-
-
Chen, X.1
Su, Y.2
Fingleton, B.3
Acuff, H.4
Matrisian, L.M.5
Zent, R.6
Pozzi, A.7
-
53
-
-
41949136687
-
The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells
-
Chen M, Chen LM, Lin CY, Chai KX (2008) The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells. Biochim Biophys Acta Mol Cell Res 1783:896-903
-
(2008)
Biochim Biophys Acta Mol Cell Res
, vol.1783
, pp. 896-903
-
-
Chen, M.1
Chen, L.M.2
Lin, C.Y.3
Chai, K.X.4
-
54
-
-
70350439830
-
Prostasin regulates iNOS and cyclin D1 expression by modulating protease-Activated receptor-2 signaling in prostate epithelial cells
-
Chen LM, Hatfield ML, Fu YY, Chai KX (2009) Prostasin regulates iNOS and cyclin D1 expression by modulating protease-Activated receptor-2 signaling in prostate epithelial cells. Prostate 69:1790-1801
-
(2009)
Prostate
, vol.69
, pp. 1790-1801
-
-
Chen, L.M.1
Hatfield, M.L.2
Fu, Y.Y.3
Chai, K.X.4
-
55
-
-
79951702955
-
Bortezomib as the first proteasome inhibitor anticancer drug: Current status and future perspectives
-
Chen D, Frezza M, Schmitt S, Kanwar J, Dou QP (2011) Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr Cancer Drug Targets 11:239-253
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 239-253
-
-
Chen, D.1
Frezza, M.2
Schmitt, S.3
Kanwar, J.4
Dou, Q.P.5
-
56
-
-
26244454970
-
Gene expression in rats with Barrett's esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux
-
Cheng P, Gong J, Wang T, Chen J, Liu GS, Zhang R (2005) Gene expression in rats with Barrett's esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux. World J Gastroenterol 11:5117-5122
-
(2005)
World J Gastroenterol
, vol.11
, pp. 5117-5122
-
-
Cheng, P.1
Gong, J.2
Wang, T.3
Chen, J.4
Liu, G.S.5
Zhang, R.6
-
57
-
-
78751591392
-
The von Hippel-Lindau tumor suppressor protein is destabilized by src: Implications for tumor angiogenesis and progression
-
Chou MT, Anthony J, Bjorge JD, Fujita DJ (2010) The von Hippel-Lindau tumor suppressor protein is destabilized by src: implications for tumor angiogenesis and progression. Genes Cancer 1:225-238
-
(2010)
Genes Cancer
, vol.1
, pp. 225-238
-
-
Chou, M.T.1
Anthony, J.2
Bjorge, J.D.3
Fujita, D.J.4
-
58
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark JP, Cooper CS (2009) ETS gene fusions in prostate cancer. Nat Rev Urol 6:429-439
-
(2009)
Nat Rev Urol
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
59
-
-
76449094879
-
The therapeutic potential of deubiquitinating enzyme inhibitors
-
Colland F (2010) The therapeutic potential of deubiquitinating enzyme inhibitors. Biochem Soc Trans 38:137-143
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 137-143
-
-
Colland, F.1
-
60
-
-
61449117010
-
Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival
-
Cordes C, Bartling B, Simm A, Afar D, Lautenschlager C, Hansen G, Silber RE, Burdach S, Hofmann HS (2009) Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival. Lung Cancer 64:79-85
-
(2009)
Lung Cancer
, vol.64
, pp. 79-85
-
-
Cordes, C.1
Bartling, B.2
Simm, A.3
Afar, D.4
Lautenschlager, C.5
Hansen, G.6
Silber, R.E.7
Burdach, S.8
Hofmann, H.S.9
-
61
-
-
0032534596
-
Matrix metalloproteinases generate angiostatin: Effects on neovascularization
-
Cornelius LA, Nehring LC, Harding E, Bolanowski M, Welgus HG, Kobayashi DK, Pierce RA, Shapiro SD (1998) Matrix metalloproteinases generate angiostatin: effects on neovascularization. J Immunol 161:6845-6852
-
(1998)
J Immunol
, vol.161
, pp. 6845-6852
-
-
Cornelius, L.A.1
Nehring, L.C.2
Harding, E.3
Bolanowski, M.4
Welgus, H.G.5
Kobayashi, D.K.6
Pierce, R.A.7
Shapiro, S.D.8
-
63
-
-
69149098620
-
Prostasin, a potential tumor marker in ovaria cancer-A pilot study
-
Costa FP, Batista Junior EL, Zelmanowicz A, Svedman C, Devenz G, Alves S, Martins da Silva AS, Garicochea B (2009) Prostasin, a potential tumor marker in ovaria cancer-A pilot study. Clinics 64:641-644
-
(2009)
Clinics
, vol.64
, pp. 641-644
-
-
Costa, F.P.1
Batista Junior, E.L.2
Zelmanowicz, A.3
Svedman, C.4
Devenz, G.5
Alves, S.6
Martins Da Silva, A.S.7
Garicochea, B.8
-
64
-
-
0034721666
-
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
-
Coussens LM, Tinkle CL, Hanahan D, Werb Z (2000) MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103:481-490
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
65
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295:2387-2392
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
66
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O, Tanaka K, Goldberg AL (1996) Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 65:801-847
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
67
-
-
50349091769
-
Matrix metalloproteinase processing of CXCL11/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding
-
Cox JH, Dean RA, Roberts CR, Overall CM (2008) Matrix metalloproteinase processing of CXCL11/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding. J Biol Chem 283:19389-19399
-
(2008)
J Biol Chem
, vol.283
, pp. 19389-19399
-
-
Cox, J.H.1
Dean, R.A.2
Roberts, C.R.3
Overall, C.M.4
-
68
-
-
69249152227
-
ADAM10 as a therapeutic target for cancer and inflammation
-
Crawford HC, Dempsey PJ, Brown G, Adam L, Moss ML (2009) ADAM10 as a therapeutic target for cancer and inflammation. Curr Pharm Des 15:2288-2299
-
(2009)
Curr Pharm des
, vol.15
, pp. 2288-2299
-
-
Crawford, H.C.1
Dempsey, P.J.2
Brown, G.3
Adam, L.4
Moss, M.L.5
-
70
-
-
2342630414
-
Implications of proteasome inhibition: An enhanced macrophage phenotype
-
Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV (2004) Implications of proteasome inhibition: an enhanced macrophage phenotype. Cell Immunol 227:140-147
-
(2004)
Cell Immunol
, vol.227
, pp. 140-147
-
-
Cuschieri, J.1
Gourlay, D.2
Garcia, I.3
Jelacic, S.4
Maier, R.V.5
-
71
-
-
84863263041
-
Topical application of activity-based probes for visualization of brain tumor tissue
-
Cutter JL, Cohen NT, Wang J, Sloan AE, Cohen AR, Panneerselvam A, Schluchter M, Blum G, Bogyo M, Basilion JP (2012) Topical application of activity-based probes for visualization of brain tumor tissue. PLoS One 7:e33060
-
(2012)
PLoS One
, vol.7
, pp. e33060
-
-
Cutter, J.L.1
Cohen, N.T.2
Wang, J.3
Sloan, A.E.4
Cohen, A.R.5
Panneerselvam, A.6
Schluchter, M.7
Blum, G.8
Bogyo, M.9
Basilion, J.P.10
-
72
-
-
27144503392
-
Proteasomes
-
Dahlmann B (2005) Proteasomes. Essays Biochem 41:31-48
-
(2005)
Essays Biochem
, vol.41
, pp. 31-48
-
-
Dahlmann, B.1
-
73
-
-
0029122808
-
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis
-
D'Armiento J, DiColandrea T, Dalal SS, Okada Y, Huang MT, Conney AH, Chada K (1995) Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis. Mol Cell Biol 15:5732-5739
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5732-5739
-
-
D'armiento, J.1
Dicolandrea, T.2
Dalal, S.S.3
Okada, Y.4
Huang, M.T.5
Conney, A.H.6
Chada, K.7
-
74
-
-
76749163281
-
Tumor detection by imaging proteolytic activity
-
Darragh MR, Schneider EL, Lou J, Phojanakong PJ, Farady CJ, Marks JD, Hann BC, Craik CS (2010) Tumor detection by imaging proteolytic activity. Cancer Res 70:1505-1512
-
(2010)
Cancer Res
, vol.70
, pp. 1505-1512
-
-
Darragh, M.R.1
Schneider, E.L.2
Lou, J.3
Phojanakong, P.J.4
Farady, C.J.5
Marks, J.D.6
Hann, B.C.7
Craik, C.S.8
-
75
-
-
40649121508
-
Evolving role of uPA/uPAR system in human cancers
-
Dass K, Ahmad A, Azmi AS, Sarkar SH, Sarkar FH (2008) Evolving role of uPA/uPAR system in human cancers. Cancer Treat Rev 34:122-136
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 122-136
-
-
Dass, K.1
Ahmad, A.2
Azmi, A.S.3
Sarkar, S.H.4
Sarkar, F.H.5
-
76
-
-
70449378957
-
Caspase substrates: Easily caught in deep waters?
-
Demon D, Van Damme P, Vanden Berghe T, Vandekerckhove J, Declercq W, Gevaert K, Vandenabeele P (2009) Caspase substrates: easily caught in deep waters?. Trends Biotechnol 27:680-688
-
(2009)
Trends Biotechnol
, vol.27
, pp. 680-688
-
-
Demon, D.1
Van Damme, P.2
Vanden Berghe, T.3
Vandekerckhove, J.4
Declercq, W.5
Gevaert, K.6
Vandenabeele, P.7
-
77
-
-
0037566830
-
Prostate-specific antigen (PSA) protein does not affect growth of prostate cancer cells InVitro or prostate cancer xenografts in vivo
-
Denmeade SR, Litvinov I, Sokoll LJ, Lilja H, Isaacs JT (2003) Prostate-specific antigen (PSA) protein does not affect growth of prostate cancer cells InVitro or prostate cancer xenografts in vivo. Prostate 56:45-53
-
(2003)
Prostate
, vol.56
, pp. 45-53
-
-
Denmeade, S.R.1
Litvinov, I.2
Sokoll, L.J.3
Lilja, H.4
Isaacs, J.T.5
-
78
-
-
77949656494
-
Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
-
Dennemarker J, Lohmuller T, Mayerle J, Tacke M, Lerch MM, Coussens LM, Peters C, Reinheckel T (2010) Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis. Oncogene 29:1611-1621
-
(2010)
Oncogene
, vol.29
, pp. 1611-1621
-
-
Dennemarker, J.1
Lohmuller, T.2
Mayerle, J.3
Tacke, M.4
Lerch, M.M.5
Coussens, L.M.6
Peters, C.7
Reinheckel, T.8
-
79
-
-
0031656568
-
Prostate-specific antigen: Its usefulness in clinical medicine
-
Diamandis EP (1998) Prostate-specific antigen: its usefulness in clinical medicine. Trends Endocrinol Metab 9:310-316
-
(1998)
Trends Endocrinol Metab
, vol.9
, pp. 310-316
-
-
Diamandis, E.P.1
-
80
-
-
52949151513
-
Protease proteomics: Revealing protease in vivo functions using systems biology approaches
-
Doucet A, Overall CM (2008) Protease proteomics: revealing protease in vivo functions using systems biology approaches. Mol Aspects Med 29:339-358
-
(2008)
Mol Aspects Med
, vol.29
, pp. 339-358
-
-
Doucet, A.1
Overall, C.M.2
-
81
-
-
11144358280
-
Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: Implications for combination therapy
-
Dragnev KH, Pitha-Rowe I, Ma Y, Petty WJ, Sekula D, Murphy B, Rendi M, Suh N, Desai NB, Sporn MB, Freemantle SJ, Dmitrovsky E (2004) Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clin Cancer Res 10:2570-2577
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2570-2577
-
-
Dragnev, K.H.1
Pitha-Rowe, I.2
Ma, Y.3
Petty, W.J.4
Sekula, D.5
Murphy, B.6
Rendi, M.7
Suh, N.8
Desai, N.B.9
Sporn, M.B.10
Freemantle, S.J.11
Dmitrovsky, E.12
-
82
-
-
0031034160
-
Activation of the cell death program by inhibition of proteasome function
-
Drexler HC (1997) Activation of the cell death program by inhibition of proteasome function. Proc Natl Acad Sci U S A 94:855-860
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 855-860
-
-
Drexler, H.C.1
-
83
-
-
0033965742
-
Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells
-
Drexler HC, Risau W, Konerding MA (2000) Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells. FASEB J 14:65-77
-
(2000)
FASEB J
, vol.14
, pp. 65-77
-
-
Drexler, H.C.1
Risau, W.2
Konerding, M.A.3
-
84
-
-
78651291555
-
ADAMTS-2 functions as anti-Angiogenic and anti-Tumoral molecule independently of its catalytic activity
-
Dubail J, Kesteloot F, Deroanne C, Motte P, Lambert V, Rakic JM, Lapiere C, Nusgens B, Colige A (2010) ADAMTS-2 functions as anti-Angiogenic and anti-Tumoral molecule independently of its catalytic activity. Cell Mol Life Sci 67:4213-4232
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 4213-4232
-
-
Dubail, J.1
Kesteloot, F.2
Deroanne, C.3
Motte, P.4
Lambert, V.5
Rakic, J.M.6
Lapiere, C.7
Nusgens, B.8
Colige, A.9
-
85
-
-
0025527558
-
Plasminogen activators and cancer
-
Duffy MJ (1990) Plasminogen activators and cancer. Blood Coagul Fibrinol 1:681-687
-
(1990)
Blood Coagul Fibrinol
, vol.1
, pp. 681-687
-
-
Duffy, M.J.1
-
86
-
-
0347917028
-
The urokinase plasminogen activator system: Role in malignancy
-
Duffy MJ (2004) The urokinase plasminogen activator system: Role in malignancy. Curr Pharm Des 10:39-49
-
(2004)
Curr Pharm des
, vol.10
, pp. 39-49
-
-
Duffy, M.J.1
-
87
-
-
0023735157
-
Urokinaseplasminogen activator, a marker for aggressive breast carcinomas-A preliminary report
-
Duffy MJ, Ogrady P, Devaney D, Osiorain L, Fennelly JJ, Lijnen HJ (1988) Urokinaseplasminogen activator, a marker for aggressive breast carcinomas-A preliminary report. Cancer 62:531-533
-
(1988)
Cancer
, vol.62
, pp. 531-533
-
-
Duffy, M.J.1
Ogrady, P.2
Devaney, D.3
Osiorain, L.4
Fennelly, J.J.5
Lijnen, H.J.6
-
88
-
-
0033522917
-
The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of betacatenin-lymphocyte enhancer-binding factor signaling
-
Easwaran V, Song V, Polakis P, Byers S (1999) The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of betacatenin-lymphocyte enhancer-binding factor signaling. J Biol Chem 274:16641-16645
-
(1999)
J Biol Chem
, vol.274
, pp. 16641-16645
-
-
Easwaran, V.1
Song, V.2
Polakis, P.3
Byers, S.4
-
89
-
-
68349148319
-
Noninvasive optical imaging of apoptosis by caspase-Targeted activity-based probes
-
Edgington LE, Berger AB, Blum G, Albrow VE, Paulick MG, Lineberry N, Bogyo M (2009) Noninvasive optical imaging of apoptosis by caspase-Targeted activity-based probes. Nat Med 15:967-973
-
(2009)
Nat Med
, vol.15
, pp. 967-973
-
-
Edgington, L.E.1
Berger, A.B.2
Blum, G.3
Albrow, V.E.4
Paulick, M.G.5
Lineberry, N.6
Bogyo, M.7
-
91
-
-
84900149335
-
-
Edwards DR, Hoyer-Hansen G, Blasi F, Sloane BF (eds). New York\ Springer
-
Edwards DR, Hoyer-Hansen G, Blasi F, Sloane BF (eds) (2008) The cancer degradome-proteases and cancer biology. Springer, New York\
-
(2008)
The cancer degradome-proteases and cancer biology
-
-
-
92
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2:161-174
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
93
-
-
0041633801
-
Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells
-
Eguchi H, Herschenhous N, Kuzushita N, Moss SF (2003) Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells. Cancer Res 63:4739-4746
-
(2003)
Cancer Res
, vol.63
, pp. 4739-4746
-
-
Eguchi, H.1
Herschenhous, N.2
Kuzushita, N.3
Moss, S.F.4
-
94
-
-
77952674017
-
Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis
-
El Hour M, Moncada-Pazos A, Blacher S, Masset A, Cal S, Berndt S, Detilleux J, Host L, Obaya AJ, Maillard C, Foidart JM, Ectors F, Noel A, Lopez-Otin C (2010) Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis. Oncogene 29:3025-3032
-
(2010)
Oncogene
, vol.29
, pp. 3025-3032
-
-
El Hour, M.1
Moncada-Pazos, A.2
Blacher, S.3
Masset, A.4
Cal, S.5
Berndt, S.6
Detilleux, J.7
Host, L.8
Obaya, A.J.9
Maillard, C.10
Foidart, J.M.11
Ectors, F.12
Noel, A.13
Lopez-Otin, C.14
-
95
-
-
78149358974
-
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-Tumor efficacy in a pancreatic cancer model
-
Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA (2010) Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-Tumor efficacy in a pancreatic cancer model. Biochimie 92:1618-1624
-
(2010)
Biochimie
, vol.92
, pp. 1618-1624
-
-
Elie, B.T.1
Gocheva, V.2
Shree, T.3
Dalrymple, S.A.4
Holsinger, L.J.5
Joyce, J.A.6
-
96
-
-
0024508318
-
Plasminogen activation initiated by single-chain urokinasetype plasminogen-Activator-potentiation by U937 monocytes
-
Ellis V, Scully MF, Kakkar VV (1989) Plasminogen activation initiated by single-chain urokinasetype plasminogen-Activator-potentiation by U937 monocytes. J Biol Chem 264:2185-2188
-
(1989)
J Biol Chem
, vol.264
, pp. 2185-2188
-
-
Ellis, V.1
Scully, M.F.2
Kakkar, V.V.3
-
97
-
-
57849100048
-
Hypoxiainduced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ (2009) Hypoxiainduced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 15:35-44
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
Le, Q.T.7
Giaccia, A.J.8
-
98
-
-
77953694906
-
The potential role of ubiquitin c-Terminal hydrolases in oncogenesis
-
Fang Y, Fu D, Shen XZ (2010) The potential role of ubiquitin c-Terminal hydrolases in oncogenesis. Biochim Biophys Acta 1806:1-6
-
(2010)
Biochim Biophys Acta
, vol.1806
, pp. 1-6
-
-
Fang, Y.1
Fu, D.2
Shen, X.Z.3
-
99
-
-
0037062449
-
Neuronal loss and brain atrophy in mice lacking cathepsins B and L
-
Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT, Olsen BR (2002) Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A 99:7883-7888
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7883-7888
-
-
Felbor, U.1
Kessler, B.2
Mothes, W.3
Goebel, H.H.4
Ploegh, H.L.5
Bronson, R.T.6
Olsen, B.R.7
-
100
-
-
32944459251
-
Matrix metalloproteinases: Roles in cancer and metastasis
-
Fingleton B (2006) Matrix metalloproteinases: roles in cancer and metastasis. Front Biosci 11:479-491
-
(2006)
Front Biosci
, vol.11
, pp. 479-491
-
-
Fingleton, B.1
-
101
-
-
0037969805
-
The clinical significance of cathepsin S expression in human astrocytomas
-
Flannery T, Gibson D, Mirakhur M, McQuaid S, Greenan C, Trimble A, Walker B, McCormick D, Johnston PG (2003) The clinical significance of cathepsin S expression in human astrocytomas. Am J Pathol 163:175-182
-
(2003)
Am J Pathol
, vol.163
, pp. 175-182
-
-
Flannery, T.1
Gibson, D.2
Mirakhur, M.3
McQuaid, S.4
Greenan, C.5
Trimble, A.6
Walker, B.7
McCormick, D.8
Johnston, P.G.9
-
102
-
-
33745918920
-
Cathepsin S expression: An independent prognostic factor in glioblastoma tumours-A pilot study
-
Flannery T, McQuaid S, McGoohan C, McConnell RS, McGregor G, Mirakhur M, Hamilton P, Diamond J, Cran G, Walker B, Scott C, Martin L, Ellison D, Patel C, Nicholson C, Mendelow D, McCormick D, Johnston PG (2006) Cathepsin S expression: an independent prognostic factor in glioblastoma tumours-A pilot study. Int J Cancer 119:854-860
-
(2006)
Int J Cancer
, vol.119
, pp. 854-860
-
-
Flannery, T.1
McQuaid, S.2
McGoohan, C.3
McConnell, R.S.4
McGregor, G.5
Mirakhur, M.6
Hamilton, P.7
Diamond, J.8
Cran, G.9
Walker, B.10
Scott, C.11
Martin, L.12
Ellison, D.13
Patel, C.14
Nicholson, C.15
Mendelow, D.16
McCormick, D.17
Johnston, P.G.18
-
103
-
-
79954524112
-
Mechanism of cell adaptation: When and how do cancer cells develop chemoresistance?
-
Fodale V, Pierobon M, Liotta L, Petricoin E (2011) Mechanism of cell adaptation: when and how do cancer cells develop chemoresistance?. Cancer J 17:89-95
-
(2011)
Cancer J
, vol.17
, pp. 89-95
-
-
Fodale, V.1
Pierobon, M.2
Liotta, L.3
Petricoin, E.4
-
104
-
-
33644822482
-
In vitro inhibition of matriptase prevents invasive growth of cell lines of prostate and colon carcinoma
-
Forbs D, Thiel S, Stella MC, Sturzebecher A, Schweinitz A, Steinmetzer T, Sturzebecher J, Uhland K (2005) In vitro inhibition of matriptase prevents invasive growth of cell lines of prostate and colon carcinoma. Int J Oncol 27:1061-1070
-
(2005)
Int J Oncol
, vol.27
, pp. 1061-1070
-
-
Forbs, D.1
Thiel, S.2
Stella, M.C.3
Sturzebecher, A.4
Schweinitz, A.5
Steinmetzer, T.6
Sturzebecher, J.7
Uhland, K.8
-
105
-
-
54749146365
-
Tube travel: The role of proteases in individual and collective cancer cell invasion
-
Friedl P, Wolf K (2008) Tube travel: the role of proteases in individual and collective cancer cell invasion. Cancer Res 68:7247-7249
-
(2008)
Cancer Res
, vol.68
, pp. 7247-7249
-
-
Friedl, P.1
Wolf, K.2
-
106
-
-
1842629839
-
Cathepsins in basal cell carcinomas: Activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L
-
Frohlich E, Mohrle M, Klessen C (2004) Cathepsins in basal cell carcinomas: activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L. Arch Dermatol Res 295:411-421
-
(2004)
Arch Dermatol Res
, vol.295
, pp. 411-421
-
-
Frohlich, E.1
Mohrle, M.2
Klessen, C.3
-
107
-
-
78049244413
-
Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration
-
Fry JL, Toker A (2010) Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration. Cancer Res 70:8187-8198
-
(2010)
Cancer Res
, vol.70
, pp. 8187-8198
-
-
Fry, J.L.1
Toker, A.2
-
108
-
-
5344230112
-
CVS-3983, a selective matriptase inhibitor, suppresses the growth of androgen independent prostate tumor xenografts
-
Galkin AV, Mullen L, Fox WD, Brown J, Duncan D, Moreno O, Madison EL, Agus DB (2004) CVS-3983, a selective matriptase inhibitor, suppresses the growth of androgen independent prostate tumor xenografts. Prostate 61:228-235
-
(2004)
Prostate
, vol.61
, pp. 228-235
-
-
Galkin, A.V.1
Mullen, L.2
Fox, W.D.3
Brown, J.4
Duncan, D.5
Moreno, O.6
Madison, E.L.7
Agus, D.B.8
-
109
-
-
0029811213
-
Fibrinolysis components as prognostic markers in breast cancer and colorectal carcinoma
-
Gandolfo GM, Conti L, Vercillo M (1996) Fibrinolysis components as prognostic markers in breast cancer and colorectal carcinoma. Anticancer Res 16:2155-2159
-
(1996)
Anticancer Res
, vol.16
, pp. 2155-2159
-
-
Gandolfo, G.M.1
Conti, L.2
Vercillo, M.3
-
110
-
-
76549092128
-
Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-Associated cancer
-
Garg P, Sarma D, Jeppsson S, Patel NR, Gewirtz AT, Merlin D, Sitaraman SV (2010) Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-Associated cancer. Cancer Res 70:792-801
-
(2010)
Cancer Res
, vol.70
, pp. 792-801
-
-
Garg, P.1
Sarma, D.2
Jeppsson, S.3
Patel, N.R.4
Gewirtz, A.T.5
Merlin, D.6
Sitaraman, S.V.7
-
111
-
-
0033539925
-
Protein stabilization: A common consequence of mutations in independently derived v-Myc alleles
-
Gavine PR, Neil JC, Crouch DH (1999) Protein stabilization: a common consequence of mutations in independently derived v-Myc alleles. Oncogene 18:7552-7558
-
(1999)
Oncogene
, vol.18
, pp. 7552-7558
-
-
Gavine, P.R.1
Neil, J.C.2
Crouch, D.H.3
-
112
-
-
68049143304
-
Apoptosis and cancer: Mutations within caspase genes
-
Ghavami S, Hashemi M, Ande SR, Yeganeh B, Xiao W, Eshraghi M, Bus CJ, Kadkhoda K, Wiechec E, Halayko AJ, Los M (2009) Apoptosis and cancer: mutations within caspase genes. J Med Genet 46:497-510
-
(2009)
J Med Genet
, vol.46
, pp. 497-510
-
-
Ghavami, S.1
Hashemi, M.2
Ande, S.R.3
Yeganeh, B.4
Xiao, W.5
Eshraghi, M.6
Bus, C.J.7
Kadkhoda, K.8
Wiechec, E.9
Halayko, A.J.10
Los, M.11
-
113
-
-
79954992761
-
ADAM10 overexpression shifts lympho-And myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch
-
Gibb DR, Saleem SJ, Kang DJ, Subler MA, Conrad DH (2011) ADAM10 overexpression shifts lympho-And myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. J Immunol 186:4244-4252
-
(2011)
J Immunol
, vol.186
, pp. 4244-4252
-
-
Gibb, D.R.1
Saleem, S.J.2
Kang, D.J.3
Subler, M.A.4
Conrad, D.H.5
-
114
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA (2006) Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev 20:543-556
-
(2006)
Genes Dev
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
Zeng, W.2
Ke, D.3
Klimstra, D.4
Reinheckel, T.5
Peters, C.6
Hanahan, D.7
Joyce, J.A.8
-
115
-
-
77955964441
-
Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer
-
Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA (2010) Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer. Biol Chem 391:937-945
-
(2010)
Biol Chem
, vol.391
, pp. 937-945
-
-
Gocheva, V.1
Chen, X.2
Peters, C.3
Reinheckel, T.4
Joyce, J.A.5
-
116
-
-
84860557204
-
Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice
-
Gopinathan A, Denicola GM, Frese KK, Cook N, Karreth FA, Mayerle J, Lerch MM, Reinheckel T, Tuveson DA (2012) Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice. Gut 61(6):877-884
-
(2012)
Gut
, vol.61
, Issue.6
, pp. 877-884
-
-
Gopinathan, A.1
Denicola, G.M.2
Frese, K.K.3
Cook, N.4
Karreth, F.A.5
Mayerle, J.6
Lerch, M.M.7
Reinheckel, T.8
Tuveson, D.A.9
-
117
-
-
77955375925
-
Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation
-
Gopinath S, Malia RR, Gondi CS, Alapati K, Fassett D, Klopfenstein JD, Dinh DH, Gujrati M, Rao JS (2010) Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation. PLoS One 5:e11668
-
(2010)
PLoS One
, vol.5
, pp. e11668
-
-
Gopinath, S.1
Malia, R.R.2
Gondi, C.S.3
Alapati, K.4
Fassett, D.5
Klopfenstein, J.D.6
Dinh, D.H.7
Gujrati, M.8
Rao, J.S.9
-
118
-
-
1942470581
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
-
Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A (2004) A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Mol Cell 14:207-219
-
(2004)
Mol Cell
, vol.14
, pp. 207-219
-
-
Goulet, B.1
Baruch, A.2
Moon, N.S.3
Poirier, M.4
Sansregret, L.L.5
Erickson, A.6
Bogyo, M.7
Nepveu, A.8
-
119
-
-
33748741293
-
A novel proteolytically processed CDP/Cux isoform of 90 kDa is generated by cathepsin L
-
Goulet B, Truscott M, Nepveu A (2006) A novel proteolytically processed CDP/Cux isoform of 90 kDa is generated by cathepsin L. Biol Chem 387:1285-1293
-
(2006)
Biol Chem
, vol.387
, pp. 1285-1293
-
-
Goulet, B.1
Truscott, M.2
Nepveu, A.3
-
120
-
-
34548689404
-
Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation
-
Goulet B, Sansregret L, Leduy L, Bogyo M, Weber E, Chauhan SS, Nepveu A (2007) Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Mol Cancer Res 5:899-907
-
(2007)
Mol Cancer Res
, vol.5
, pp. 899-907
-
-
Goulet, B.1
Sansregret, L.2
Leduy, L.3
Bogyo, M.4
Weber, E.5
Chauhan, S.S.6
Nepveu, A.7
-
121
-
-
51449115025
-
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth
-
Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Ploegh HL, Barrett TA, Weissleder R, Khazaie K (2008) Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS One 3:e2916
-
(2008)
PLoS One
, vol.3
, pp. e2916
-
-
Gounaris, E.1
Tung, C.H.2
Restaino, C.3
Maehr, R.4
Kohler, R.5
Joyce, J.A.6
Ploegh, H.L.7
Barrett, T.A.8
Weissleder, R.9
Khazaie, K.10
-
122
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140:883-899
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
123
-
-
79951819880
-
UPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma
-
Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS (2011) uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma. PLoS One 6: e17123
-
(2011)
PLoS One
, vol.6
, pp. e17123
-
-
Gupta, R.1
Nalla, A.K.2
Gogineni, V.R.3
Chetty, C.4
Bhoopathi, P.5
Klopfenstein, J.D.6
Tsung, A.J.7
Mohanam, S.8
Rao, J.S.9
-
124
-
-
34547735561
-
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8)
-
Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS (2007) Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8). FASEB J 21:2580-2591
-
(2007)
FASEB J
, vol.21
, pp. 2580-2591
-
-
Gutierrez-Fernandez, A.1
Inada, M.2
Balbin, M.3
Fueyo, A.4
Pitiot, A.S.5
Astudillo, A.6
Hirose, K.7
Hirata, M.8
Shapiro, S.D.9
Noel, A.10
Werb, Z.11
Krane, S.M.12
Lopez-Otin, C.13
Puente, X.S.14
-
125
-
-
0035110730
-
Overexpression of membrane-Type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice
-
Ha HY, Moon HB, Nam MS, Lee JW, Ryoo ZY, Lee TH, Lee KK, So BJ, Sato H, Seiki M, Yu DY (2001) Overexpression of membrane-Type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice. Cancer Res 61:984-990
-
(2001)
Cancer Res
, vol.61
, pp. 984-990
-
-
Ha, H.Y.1
Moon, H.B.2
Nam, M.S.3
Lee, J.W.4
Ryoo, Z.Y.5
Lee, T.H.6
Lee, K.K.7
So, B.J.8
Sato, H.9
Seiki, M.10
Yu, D.Y.11
-
126
-
-
12344271817
-
The human cysteine protease cathepsin v can compensate for murine cathepsin L in mouse epidermis and hair follicles
-
Hagemann S, Gunther T, Dennemarker J, Lohmuller T, Bromme D, Schule R, Peters C, Reinheckel T (2004) The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles. Eur J Cell Biol 83:775-780
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 775-780
-
-
Hagemann, S.1
Gunther, T.2
Dennemarker, J.3
Lohmuller, T.4
Bromme, D.5
Schule, R.6
Peters, C.7
Reinheckel, T.8
-
127
-
-
45149134605
-
Re-educating tumor-Associated macrophages by targeting NF-kappaB
-
Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG, Robinson SC, Balkwill FR (2008) 'Re-educating' tumor-Associated macrophages by targeting NF-kappaB. J Exp Med 205:1261-1268
-
(2008)
J Exp Med
, vol.205
, pp. 1261-1268
-
-
Hagemann, T.1
Lawrence, T.2
McNeish, I.3
Charles, K.A.4
Kulbe, H.5
Thompson, R.G.6
Robinson, S.C.7
Balkwill, F.R.8
-
128
-
-
10744223801
-
Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin
-
Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R (2003) Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell 3:589-601
-
(2003)
Cancer Cell
, vol.3
, pp. 589-601
-
-
Hamano, Y.1
Zeisberg, M.2
Sugimoto, H.3
Lively, J.C.4
Maeshima, Y.5
Yang, C.6
Hynes, R.O.7
Werb, Z.8
Sudhakar, A.9
Kalluri, R.10
-
129
-
-
24644441893
-
Urokinase-Type plasminogen activator system and breast cancer (Review)
-
Han B, Nakamura M, Mori I, Nakamura Y, Kakudo K (2005) Urokinase-Type plasminogen activator system and breast cancer (Review). Oncol Rep 14:105-112
-
(2005)
Oncol Rep
, vol.14
, pp. 105-112
-
-
Han, B.1
Nakamura, M.2
Mori, I.3
Nakamura, Y.4
Kakudo, K.5
-
130
-
-
70249140303
-
Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells
-
Hanson EM, Clements VK, Sinha P, Ilkovitch D, Ostrand-Rosenberg S (2009) Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells. J Immunol 183:937-944
-
(2009)
J Immunol
, vol.183
, pp. 937-944
-
-
Hanson, E.M.1
Clements, V.K.2
Sinha, P.3
Ilkovitch, D.4
Ostrand-Rosenberg, S.5
-
131
-
-
78650915537
-
Deubiquitinases in the regulation of NF-kappaB signaling
-
Harhaj EW, Dixit VM (2011) Deubiquitinases in the regulation of NF-kappaB signaling. Cell Res 21:22-39
-
(2011)
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
132
-
-
39449098165
-
Interactions of myeloma cells with osteoclasts promote tumour expansion and bone degradation through activation of a complex signalling network and upregulation of cathepsin K, matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA)
-
Hecht M, von Metzler I, Sack K, Kaiser M, Sezer O (2008) Interactions of myeloma cells with osteoclasts promote tumour expansion and bone degradation through activation of a complex signalling network and upregulation of cathepsin K, matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA). Exp Cell Res 314:1082-1093
-
(2008)
Exp Cell Res
, vol.314
, pp. 1082-1093
-
-
Hecht, M.1
Von Metzler, I.2
Sack, K.3
Kaiser, M.4
Sezer, O.5
-
133
-
-
0036882394
-
Serine protease mechanism and specificity
-
Hedstrom L (2002) Serine protease mechanism and specificity. Chem Rev 102:4501-4524
-
(2002)
Chem Rev
, vol.102
, pp. 4501-4524
-
-
Hedstrom, L.1
-
134
-
-
18444389451
-
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
-
Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S (2002) Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109:625-637
-
(2002)
Cell
, vol.109
, pp. 625-637
-
-
Heissig, B.1
Hattori, K.2
Dias, S.3
Friedrich, M.4
Ferris, B.5
Hackett, N.R.6
Crystal, R.G.7
Besmer, P.8
Lyden, D.9
Moore, M.A.10
Werb, Z.11
Rafii, S.12
-
135
-
-
20444369579
-
Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases
-
Heljasvaara R, Nyberg P, Luostarinen J, Parikka M, Heikkila P, Rehn M, Sorsa T, Salo T, Pihlajaniemi T (2005) Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases. Exp Cell Res 307:292-304
-
(2005)
Exp Cell Res
, vol.307
, pp. 292-304
-
-
Heljasvaara, R.1
Nyberg, P.2
Luostarinen, J.3
Parikka, M.4
Heikkila, P.5
Rehn, M.6
Sorsa, T.7
Salo, T.8
Pihlajaniemi, T.9
-
136
-
-
84884211491
-
Macrophage cathepsin K promotes tumor progression in bone
-
Herroon MK, Rajagurubandara E, Rudy D, Chalasani A, Hardaway AL, Podgorski I (2013) Macrophage cathepsin K promotes tumor progression in bone. Oncogene 32(12):1580-1593
-
(2013)
Oncogene
, vol.32
, Issue.12
, pp. 1580-1593
-
-
Herroon, M.K.1
Rajagurubandara, E.2
Rudy, D.3
Chalasani, A.4
Hardaway, A.L.5
Podgorski, I.6
-
137
-
-
21244448682
-
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-Anchored serine protease implicated in prostate and ovarian cancers
-
Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhattt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ (2005) Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-Anchored serine protease implicated in prostate and ovarian cancers. Biochem J 390:125-136
-
(2005)
Biochem J
, vol.390
, pp. 125-136
-
-
Herter, S.1
Piper, D.E.2
Aaron, W.3
Gabriele, T.4
Cutler, G.5
Cao, P.6
Bhattt, A.S.7
Choe, Y.8
Craik, C.S.9
Walker, N.10
Meininger, D.11
Hoey, T.12
Austin, R.J.13
-
138
-
-
0029894671
-
Stromal cell expression of components of matrix-degrading protease systems in human cancer
-
Hewitt R, Dano K (1996) Stromal cell expression of components of matrix-degrading protease systems in human cancer. Enzyme Protein 49:163-173
-
(1996)
Enzyme Protein
, vol.49
, pp. 163-173
-
-
Hewitt, R.1
Dano, K.2
-
139
-
-
0033168561
-
Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors
-
Hooper JD, Nicol DL, Dickinson JL, Eyre HJ, Scarman AL, Normyle JF, Stuttgen MA, Douglas ML, Loveland KAL, Sutherland GR, Antalis TM (1999) Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors. Cancer Res 59:3199-3205
-
(1999)
Cancer Res
, vol.59
, pp. 3199-3205
-
-
Hooper, J.D.1
Nicol, D.L.2
Dickinson, J.L.3
Eyre, H.J.4
Scarman, A.L.5
Normyle, J.F.6
Stuttgen, M.A.7
Douglas, M.L.8
Loveland, K.A.L.9
Sutherland, G.R.10
Antalis, T.M.11
-
140
-
-
0034697749
-
Localization, expression and genomic structure of the gene encoding the human serine protease testisin
-
Hooper JD, Bowen N, Marshall H, Cullen LM, Sood R, Daniels R, Stuttgen MA, Normyle JF, Higgs DR, Kastner DL, Ogbourne SM, Pera MF, Jazwinska EC, Antalis TM (2000) Localization, expression and genomic structure of the gene encoding the human serine protease testisin. Biochim Biophys Acta Gene Struct Expr 1492:63-71
-
(2000)
Biochim Biophys Acta Gene Struct Expr
, vol.1492
, pp. 63-71
-
-
Hooper, J.D.1
Bowen, N.2
Marshall, H.3
Cullen, L.M.4
Sood, R.5
Daniels, R.6
Stuttgen, M.A.7
Normyle, J.F.8
Higgs, D.R.9
Kastner, D.L.10
Ogbourne, S.M.11
Pera, M.F.12
Jazwinska, E.C.13
Antalis, T.M.14
-
141
-
-
33745700206
-
Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases
-
Houghton AM, Grisolano JL, Baumann ML, Kobayashi DK, Hautamaki RD, Nehring LC, Cornelius LA, Shapiro SD (2006) Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. Cancer Res 66:6149-6155
-
(2006)
Cancer Res
, vol.66
, pp. 6149-6155
-
-
Houghton, A.M.1
Grisolano, J.L.2
Baumann, M.L.3
Kobayashi, D.K.4
Hautamaki, R.D.5
Nehring, L.C.6
Cornelius, L.A.7
Shapiro, S.D.8
-
142
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R, Hung MC (2004) IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117:225-237
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
Lee, D.F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.Y.6
Zou, Y.7
Bao, S.8
Hanada, N.9
Saso, H.10
Kobayashi, R.11
Hung, M.C.12
-
143
-
-
70350231667
-
Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis
-
Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y (2009) Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis. Cancer Res 69:7529-7537
-
(2009)
Cancer Res
, vol.69
, pp. 7529-7537
-
-
Huang, Y.1
Song, N.2
Ding, Y.3
Yuan, S.4
Li, X.5
Cai, H.6
Shi, H.7
Luo, Y.8
-
144
-
-
0032514743
-
A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma
-
Hughes SJ, Glover TW, Zhu XX, Kuick R, Thoraval D, Orringer MB, Beer DG, Hanash S (1998) A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma. Proc Natl Acad Sci U S A 95:12410-12415
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 12410-12415
-
-
Hughes, S.J.1
Glover, T.W.2
Zhu, X.X.3
Kuick, R.4
Thoraval, D.5
Orringer, M.B.6
Beer, D.G.7
Hanash, S.8
-
145
-
-
0036674370
-
Expression microarray analysis of brain tumors: What have we learned so far
-
Hunter SB, Moreno CS (2002) Expression microarray analysis of brain tumors: what have we learned so far. Front Biosci 7:c74-c82
-
(2002)
Front Biosci
, vol.7
, pp. c74-c82
-
-
Hunter, S.B.1
Moreno, C.S.2
-
146
-
-
38349023103
-
Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis
-
Husmann K, Muff R, Bolander ME, Sarkar G, Born W, Fuchs B (2008) Cathepsins and osteosarcoma: expression analysis identifies cathepsin K as an indicator of metastasis. Mol Carcinog 47:66-73
-
(2008)
Mol Carcinog
, vol.47
, pp. 66-73
-
-
Husmann, K.1
Muff, R.2
Bolander, M.E.3
Sarkar, G.4
Born, W.5
Fuchs, B.6
-
147
-
-
77951622671
-
A20: From ubiquitin editing to tumour suppression
-
Hymowitz SG, Wertz IE (2010) A20: from ubiquitin editing to tumour suppression. Nat Rev Cancer 10:332-341
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 332-341
-
-
Hymowitz, S.G.1
Wertz, I.E.2
-
148
-
-
0038129539
-
ADAMTS1: A matrix metalloprotease with angioinhibitory properties
-
Iruela-Arispe ML, Carpizo D, Luque A (2003) ADAMTS1: a matrix metalloprotease with angioinhibitory properties. Ann NY Acad Sci 995:183-190
-
(2003)
Ann NY Acad Sci
, vol.995
, pp. 183-190
-
-
Iruela-Arispe, M.L.1
Carpizo, D.2
Luque, A.3
-
149
-
-
0032031861
-
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
-
Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S (1998) Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res 58:1048-1051
-
(1998)
Cancer Res
, vol.58
, pp. 1048-1051
-
-
Itoh, T.1
Tanioka, M.2
Yoshida, H.3
Yoshioka, T.4
Nishimoto, H.5
Itohara, S.6
-
150
-
-
0032789885
-
Experimental metastasis is suppressed in MMP-9-deficient mice
-
Itoh T, Tanioka M, Matsuda H, Nishimoto H, Yoshioka T, Suzuki R, Uehira M (1999) Experimental metastasis is suppressed in MMP-9-deficient mice. Clin Exp Metastasis 17:177-181
-
(1999)
Clin Exp Metastasis
, vol.17
, pp. 177-181
-
-
Itoh, T.1
Tanioka, M.2
Matsuda, H.3
Nishimoto, H.4
Yoshioka, T.5
Suzuki, R.6
Uehira, M.7
-
151
-
-
10044296973
-
Cysteine cathepsins in human cancer
-
Jedeszko C, Sloane BF (2004) Cysteine cathepsins in human cancer. Biol Chem 385:1017-1027
-
(2004)
Biol Chem
, vol.385
, pp. 1017-1027
-
-
Jedeszko, C.1
Sloane, B.F.2
-
153
-
-
79952278967
-
The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: Results of a 4-week, double-blind, randomized, controlled trial
-
Jensen AB, Wynne C, Ramirez G, He W, Song Y, Berd Y, Wang H, Mehta A, Lombardi A (2010) The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. Clin Breast Cancer 10:452-458
-
(2010)
Clin Breast Cancer
, vol.10
, pp. 452-458
-
-
Jensen, A.B.1
Wynne, C.2
Ramirez, G.3
He, W.4
Song, Y.5
Berd, Y.6
Wang, H.7
Mehta, A.8
Lombardi, A.9
-
154
-
-
17144430502
-
The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent
-
Jodele S, Chantrain CF, Blavier L, Lutzko C, Crooks GM, Shimada H, Coussens LM, Declerck YA (2005) The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer Res 65:3200-3208
-
(2005)
Cancer Res
, vol.65
, pp. 3200-3208
-
-
Jodele, S.1
Chantrain, C.F.2
Blavier, L.3
Lutzko, C.4
Crooks, G.M.5
Shimada, H.6
Coussens, L.M.7
Declerck, Y.A.8
-
155
-
-
0031719897
-
Cancer invasion and tissue remodeling: Common themes in proteolytic matrix degradation
-
Johnsen M, Lund LR, Romer J, Almholt K, Dano K (1998) Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation. Curr Opin Cell Biol 10:667-671
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 667-671
-
-
Johnsen, M.1
Lund, L.R.2
Romer, J.3
Almholt, K.4
Dano, K.5
-
156
-
-
34248169692
-
Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: An angiotensin II type 2 receptor-mediated effect
-
Kaakinen R, Lindstedt KA, Sneck M, Kovanen PT, Oorni K (2007) Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect. Atherosclerosis 192:323-327
-
(2007)
Atherosclerosis
, vol.192
, pp. 323-327
-
-
Kaakinen, R.1
Lindstedt, K.A.2
Sneck, M.3
Kovanen, P.T.4
Oorni, K.5
-
157
-
-
0025413403
-
The role of cathepsin L in malignant transformation
-
Kane SE, Gottesman MM (1990) The role of cathepsin L in malignant transformation. Semin Cancer Biol 1:127-136
-
(1990)
Semin Cancer Biol
, vol.1
, pp. 127-136
-
-
Kane, S.E.1
Gottesman, M.M.2
-
158
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D (2005) VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438:820-827
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Bramley, A.H.4
Vincent, L.5
Costa, C.6
MacDonald, D.D.7
Jin, D.K.8
Shido, K.9
Kerns, S.A.10
Zhu, Z.11
Hicklin, D.12
Wu, Y.13
Port, J.L.14
Altorki, N.15
Port, E.R.16
Ruggero, D.17
Shmelkov, S.V.18
Jensen, K.K.19
Rafii, S.20
Lyden, D.21
more..
-
159
-
-
70149102895
-
Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17
-
Katakowski M, Jiang F, Zheng X, Gutierrez JA, Szalad A, Chopp M (2009) Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17. Cancer Sci 100:1597-1604
-
(2009)
Cancer Sci
, vol.100
, pp. 1597-1604
-
-
Katakowski, M.1
Jiang, F.2
Zheng, X.3
Gutierrez, J.A.4
Szalad, A.5
Chopp, M.6
-
160
-
-
35348962179
-
Tackling EGFR signaling with TACE antagonists: A rational target for metalloprotease inhibitors in cancer
-
Kenny PA (2007) Tackling EGFR signaling with TACE antagonists: a rational target for metalloprotease inhibitors in cancer. Expert Opin Ther Targets 11:1287-1298
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 1287-1298
-
-
Kenny, P.A.1
-
161
-
-
33846817495
-
Targeting TACE-dependent EGFR ligand shedding in breast cancer
-
Kenny PA, Bissell MJ (2007) Targeting TACE-dependent EGFR ligand shedding in breast cancer. J Clin Invest 117:337-345
-
(2007)
J Clin Invest
, vol.117
, pp. 337-345
-
-
Kenny, P.A.1
Bissell, M.J.2
-
162
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock K, Plaks V, Werb Z (2010) Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141:52-67
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
163
-
-
77952795526
-
Design, synthesis and biological application of chemical probes for bio-imaging
-
Kikuchi K (2010) Design, synthesis and biological application of chemical probes for bio-imaging. Chem Soc Rev 39:2048-2053
-
(2010)
Chem Soc Rev
, vol.39
, pp. 2048-2053
-
-
Kikuchi, K.1
-
164
-
-
34047138860
-
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
-
Kitamura T, Kometani K, Hashida H, Matsunaga A, Miyoshi H, Hosogi H, Aoki M, Oshima M, Hattori M, Takabayashi A, Minato N, Taketo MM (2007) SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet 39:467-475
-
(2007)
Nat Genet
, vol.39
, pp. 467-475
-
-
Kitamura, T.1
Kometani, K.2
Hashida, H.3
Matsunaga, A.4
Miyoshi, H.5
Hosogi, H.6
Aoki, M.7
Oshima, M.8
Hattori, M.9
Takabayashi, A.10
Minato, N.11
Taketo, M.M.12
-
165
-
-
53049084066
-
Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression
-
Kleer CG, Bloushtain-Qimron N, Chen YH, Carrasco D, Hu M, Yao J, Kraeft SK, Collins LC, Sabel MS, Argani P, Gelman R, Schnitt SJ, Krop IE, Polyak K (2008) Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression. Clin Cancer Res 14:5357-5367
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5357-5367
-
-
Kleer, C.G.1
Bloushtain-Qimron, N.2
Chen, Y.H.3
Carrasco, D.4
Hu, M.5
Yao, J.6
Kraeft, S.K.7
Collins, L.C.8
Sabel, M.S.9
Argani, P.10
Gelman, R.11
Schnitt, S.J.12
Krop, I.E.13
Polyak, K.14
-
166
-
-
79951519159
-
Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: Biological function and structure
-
Klein T, Bischoff R (2011) Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure. J Proteome Res 10:17-33
-
(2011)
J Proteome Res
, vol.10
, pp. 17-33
-
-
Klein, T.1
Bischoff, R.2
-
167
-
-
5144225237
-
Hepsin promotes prostate cancer progression and metastasis
-
Klezovitch O, Chevillet J, Mirosevich J, Roberts RL, Matusik RJ, Vasioukhin V (2004) Hepsin promotes prostate cancer progression and metastasis. Cancer Cell 6:185-195
-
(2004)
Cancer Cell
, vol.6
, pp. 185-195
-
-
Klezovitch, O.1
Chevillet, J.2
Mirosevich, J.3
Roberts, R.L.4
Matusik, R.J.5
Vasioukhin, V.6
-
168
-
-
41149097040
-
A causal role for ERG in neoplastic transformation of prostate epithelium
-
Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V (2008) A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci U S A 105:2105-2110
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2105-2110
-
-
Klezovitch, O.1
Risk, M.2
Coleman, I.3
Lucas, J.M.4
Null, M.5
True, L.D.6
Nelson, P.S.7
Vasioukhin, V.8
-
169
-
-
34548574811
-
Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion
-
Klucky B, Mueller R, Vogt I, Teurich S, Hartenstein B, Breuhahn K, Flechtenmacher C, Angel P, Hess J (2007) Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion. Cancer Res 67:8198-8206
-
(2007)
Cancer Res
, vol.67
, pp. 8198-8206
-
-
Klucky, B.1
Mueller, R.2
Vogt, I.3
Teurich, S.4
Hartenstein, B.5
Breuhahn, K.6
Flechtenmacher, C.7
Angel, P.8
Hess, J.9
-
170
-
-
70350230209
-
Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma
-
Kohga K, Takehara T, Tatsumi T, Miyagi T, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N (2009) Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma. Cancer Res 69:8050-8057
-
(2009)
Cancer Res
, vol.69
, pp. 8050-8057
-
-
Kohga, K.1
Takehara, T.2
Tatsumi, T.3
Miyagi, T.4
Ishida, H.5
Ohkawa, K.6
Kanto, T.7
Hiramatsu, N.8
Hayashi, N.9
-
171
-
-
77950613332
-
Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9
-
Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N (2010) Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. Hepatology 51:1264-1273
-
(2010)
Hepatology
, vol.51
, pp. 1264-1273
-
-
Kohga, K.1
Takehara, T.2
Tatsumi, T.3
Ishida, H.4
Miyagi, T.5
Hosui, A.6
Hayashi, N.7
-
172
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S (2009) Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 10:550-563
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
173
-
-
21044440422
-
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues
-
Kos J, Sekirnik A, Premzl A, Zavasnik Bergant V, Langerholc T, Turk B, Werle B, Golouh R, Repnik U, Jeras M, Turk V (2005) Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues. Exp Cell Res 306:103-113
-
(2005)
Exp Cell Res
, vol.306
, pp. 103-113
-
-
Kos, J.1
Sekirnik, A.2
Premzl, A.3
Zavasnik Bergant, V.4
Langerholc, T.5
Turk, B.6
Werle, B.7
Golouh, R.8
Repnik, U.9
Jeras, M.10
Turk, V.11
-
174
-
-
0037865469
-
Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia
-
Kothapalli R, Bailey RD, Kusmartseva I, Mane S, Epling-Burnette PK, Loughran TP Jr (2003) Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia. Int J Oncol 22:33-39
-
(2003)
Int J Oncol
, vol.22
, pp. 33-39
-
-
Kothapalli, R.1
Bailey, R.D.2
Kusmartseva, I.3
Mane, S.4
Epling-Burnette, P.K.5
Loughran, T.P.6
-
175
-
-
0029994046
-
Prostate-specific antigen in breast cyst fluid: Possible role of prostate-specific antigen in hormone-dependent breast cancer
-
Lai LC, Erbas H, Lennard TWJ, Peaston RT (1996) Prostate-specific antigen in breast cyst fluid: Possible role of prostate-specific antigen in hormone-dependent breast cancer. Int J Cancer 66:743-746
-
(1996)
Int J Cancer
, vol.66
, pp. 743-746
-
-
Lai, L.C.1
Erbas, H.2
Lennard, T.W.J.3
Peaston, R.T.4
-
176
-
-
75549088309
-
Target in cancer treatment?
-
Lankelma JM, Voorend DM, Barwari T, Koetsveld J, Van der Spek AH, De Porto AP, Van Rooijen G, Van Noorden CJ (2010) Cathepsin L, target in cancer treatment?. Life Sci 86:225-233
-
(2010)
Life Sci
, vol.86
, pp. 225-233
-
-
Lankelma, J.M.1
Voorend, D.M.2
Barwari, T.3
Koetsveld, J.4
Van Der Spek, A.H.5
De Porto, A.P.6
Van Rooijen, G.7
Van Noorden, C.J.8
Cathepsin, L.9
-
177
-
-
35448959223
-
A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden
-
Le Gall C, Bellahcene A, Bonnelye E, Gasser JA, Castronovo V, Green J, Zimmermann J, Clezardin P (2007) A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden. Cancer Res 67:9894-9902
-
(2007)
Cancer Res
, vol.67
, pp. 9894-9902
-
-
Le Gall, C.1
Bellahcene, A.2
Bonnelye, E.3
Gasser, J.A.4
Castronovo, V.5
Green, J.6
Zimmermann, J.7
Clezardin, P.8
-
178
-
-
22344437713
-
Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
-
Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML (2005) Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J Cell Biol 169:681-691
-
(2005)
J Cell Biol
, vol.169
, pp. 681-691
-
-
Lee, S.1
Jilani, S.M.2
Nikolova, G.V.3
Carpizo, D.4
Iruela-Arispe, M.L.5
-
179
-
-
37649020428
-
Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch
-
Lepage M, Dow WC, Melchior M, You Y, Fingleton B, Quarles CC, Pepin C, Gore JC, Matrisian LM, McIntyre JO (2007) Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch. Mol Imaging 6:393-403
-
(2007)
Mol Imaging
, vol.6
, pp. 393-403
-
-
Lepage, M.1
Dow, W.C.2
Melchior, M.3
You, Y.4
Fingleton, B.5
Quarles, C.C.6
Pepin, C.7
Gore, J.C.8
Matrisian, L.M.9
McIntyre, J.O.10
-
180
-
-
33746102980
-
Helicobacter pylori and gastric neoplasia
-
Leung WK (2006) Helicobacter pylori and gastric neoplasia. Contrib Microbiol 13:66-80
-
(2006)
Contrib Microbiol
, vol.13
, pp. 66-80
-
-
Leung, W.K.1
-
181
-
-
38649088939
-
A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis
-
Lewen S, Zhou H, Hu HD, Cheng T, Markowitz D, Reisfeld RA, Xiang R, Luo Y (2008) A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis. Cancer Immunol Immunother 57:507-515
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 507-515
-
-
Lewen, S.1
Zhou, H.2
Hu, H.D.3
Cheng, T.4
Markowitz, D.5
Reisfeld, R.A.6
Xiang, R.7
Luo, Y.8
-
182
-
-
80455173825
-
New targets for intervention in the treatment of postmenopausal osteoporosis
-
Lewiecki EM (2011) New targets for intervention in the treatment of postmenopausal osteoporosis. Nat Rev Rheumatol 7:631-638
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 631-638
-
-
Lewiecki, E.M.1
-
183
-
-
0023850048
-
A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human-liver and hepatoma-cells
-
Leytus SP, Loeb KR, Hagen FS, Kurachi K, Davie EW (1988) A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human-liver and hepatoma-cells. Biochemistry 27:1067-1074
-
(1988)
Biochemistry
, vol.27
, pp. 1067-1074
-
-
Leytus, S.P.1
Loeb, K.R.2
Hagen, F.S.3
Kurachi, K.4
Davie, E.W.5
-
184
-
-
0142074839
-
Imaging matrix metalloproteinase expression in tumors
-
Li WP, Anderson CJ (2003) Imaging matrix metalloproteinase expression in tumors. Q J Nucl Med 47:201-208
-
(2003)
Q J Nucl Med
, vol.47
, pp. 201-208
-
-
Li, W.P.1
Anderson, C.J.2
-
185
-
-
18744383614
-
Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury
-
Li Q, Park PW, Wilson CL, Parks WC (2002) Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury. Cell 111:635-646
-
(2002)
Cell
, vol.111
, pp. 635-646
-
-
Li, Q.1
Park, P.W.2
Wilson, C.L.3
Parks, W.C.4
-
186
-
-
67649506542
-
Increased levels of macrophage-secreted cathepsin S during prostate cancer progression in TRAMP mice and patients
-
Lindahl C, Simonsson M, Bergh A, Thysell E, Antti H, Sund M, Wikstrom P (2009) Increased levels of macrophage-secreted cathepsin S during prostate cancer progression in TRAMP mice and patients. Cancer Genomics Proteomics 6:149-159
-
(2009)
Cancer Genomics Proteomics
, vol.6
, pp. 149-159
-
-
Lindahl, C.1
Simonsson, M.2
Bergh, A.3
Thysell, E.4
Antti, H.5
Sund, M.6
Wikstrom, P.7
-
187
-
-
17044438329
-
Use of a transgenic mouse model to identify markers of human lung tumors
-
Linnerth NM, Sirbovan K, Moorehead RA (2005) Use of a transgenic mouse model to identify markers of human lung tumors. Int J Cancer 114:977-982
-
(2005)
Int J Cancer
, vol.114
, pp. 977-982
-
-
Linnerth, N.M.1
Sirbovan, K.2
Moorehead, R.A.3
-
188
-
-
0019195010
-
Metastatic potential correlates with enzymatic degradation of basement membrane collagen
-
Liotta LA, Tryggvason K, Garbisa S, Hart I, Foltz CM, Shafie S (1980) Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284:67-68
-
(1980)
Nature
, vol.284
, pp. 67-68
-
-
Liotta, L.A.1
Tryggvason, K.2
Garbisa, S.3
Hart, I.4
Foltz, C.M.5
Shafie, S.6
-
189
-
-
23944489424
-
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation
-
List K, Szabo R, Molinolo A, Sriuranpong V, Redeye V, Murdock T, Burke B, Nielsen BS, Gutkind JS, Bugge TH (2005) Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation. Genes Dev 19:1934-1950
-
(2005)
Genes Dev
, vol.19
, pp. 1934-1950
-
-
List, K.1
Szabo, R.2
Molinolo, A.3
Sriuranpong, V.4
Redeye, V.5
Murdock, T.6
Burke, B.7
Nielsen, B.S.8
Gutkind, J.S.9
Bugge, T.H.10
-
190
-
-
33646514271
-
Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis
-
List K, Szabo R, Molinolo A, Nielsen BS, Bugge TH (2006) Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis. Am J Pathol 168:1513-1525
-
(2006)
Am J Pathol
, vol.168
, pp. 1513-1525
-
-
List, K.1
Szabo, R.2
Molinolo, A.3
Nielsen, B.S.4
Bugge, T.H.5
-
191
-
-
73549091040
-
Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway
-
List K, Kosa P, Szabo R, Bey AL, Wang CB, Molinolo A, Bugge TH (2009) Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway. Am J Pathol 175:1453-1463
-
(2009)
Am J Pathol
, vol.175
, pp. 1453-1463
-
-
List, K.1
Kosa, P.2
Szabo, R.3
Bey, A.L.4
Wang, C.B.5
Molinolo, A.6
Bugge, T.H.7
-
192
-
-
77950266184
-
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression
-
Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI, Werb Z (2010) Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression. Cancer Res 70:2224-2234
-
(2010)
Cancer Res
, vol.70
, pp. 2224-2234
-
-
Littlepage, L.E.1
Sternlicht, M.D.2
Rougier, N.3
Phillips, J.4
Gallo, E.5
Yu, Y.6
Williams, K.7
Brenot, A.8
Gordon, J.I.9
Werb, Z.10
-
193
-
-
77954352573
-
Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis
-
Lo PH, Lung HL, Cheung AK, Apte SS, Chan KW, Kwong FM, Ko JM, Cheng Y, Law S, Srivastava G, Zabarovsky ER, Tsao SW, Tang JC, Stanbridge EJ, Lung ML (2010) Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis. Cancer Res 70:5567-5576
-
(2010)
Cancer Res
, vol.70
, pp. 5567-5576
-
-
Lo, P.H.1
Lung, H.L.2
Cheung, A.K.3
Apte, S.S.4
Chan, K.W.5
Kwong, F.M.6
Ko, J.M.7
Cheng, Y.8
Law, S.9
Srivastava, G.10
Zabarovsky, E.R.11
Tsao, S.W.12
Tang, J.C.13
Stanbridge, E.J.14
Lung, M.L.15
-
194
-
-
69249228553
-
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
-
Lu X, Wang Q, Hu G, Van Poznak C, Fleisher M, Reiss M, Massague J, Kang Y (2009) ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes Dev 23:1882-1894
-
(2009)
Genes Dev
, vol.23
, pp. 1882-1894
-
-
Lu, X.1
Wang, Q.2
Hu, G.3
Van Poznak, C.4
Fleisher, M.5
Reiss, M.6
Massague, J.7
Kang, Y.8
-
195
-
-
15244349837
-
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules
-
Ludwig A, Hundhausen C, Lambert MH, Broadway N, Andrews RC, Bickett DM, Leesnitzer MA, Becherer JD (2005) Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Comb Chem High Throughput Screen 8:161-171
-
(2005)
Comb Chem High Throughput Screen
, vol.8
, pp. 161-171
-
-
Ludwig, A.1
Hundhausen, C.2
Lambert, M.H.3
Broadway, N.4
Andrews, R.C.5
Bickett, D.M.6
Leesnitzer, M.A.7
Becherer, J.D.8
-
196
-
-
33746718151
-
Targeting tumor-Associated macrophages as a novel strategy against breast cancer
-
Luo Y, Zhou H, Krueger J, Kaplan C, Lee SH, Dolman C, Markowitz D, Wu W, Liu C, Reisfeld RA, Xiang R (2006) Targeting tumor-Associated macrophages as a novel strategy against breast cancer. J Clin Invest 116:2132-2141
-
(2006)
J Clin Invest
, vol.116
, pp. 2132-2141
-
-
Luo, Y.1
Zhou, H.2
Krueger, J.3
Kaplan, C.4
Lee, S.H.5
Dolman, C.6
Markowitz, D.7
Wu, W.8
Liu, C.9
Reisfeld, R.A.10
Xiang, R.11
-
197
-
-
41349119388
-
Proteomics analysis of Hodgkin lymphoma: Identification of new players involved in the cross-Talk between HRS cells and infiltrating lymphocytes
-
Berg A.
-
Ma Y, Visser L, Roelofsen H, de Vries M, Diepstra A, van Imhoff G, van der Wal T, Luinge M, Alvarez-Llamas G, Vos H, Poppema S, Vonk R, van den Berg A (2008) Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-Talk between HRS cells and infiltrating lymphocytes. Blood 111:2339-2346
-
(2008)
Blood
, vol.111
, pp. 2339-2346
-
-
Ma, Y.1
Visser, L.2
Roelofsen, H.3
De Vries, M.4
Diepstra, A.5
Van Imhoff, G.6
Van Der Wal, T.7
Luinge, M.8
Alvarez-Llamas, G.9
Vos, H.10
Poppema, S.11
Den Van, V.R.12
-
198
-
-
0035423118
-
Expression profiling reveals hepsin overexpression in prostate cancer
-
Magee JA, Araki T, Patil S, Ehrig T, True L, Humphrey PA, Catalona WJ, Watson MA, Milbrandt J (2001) Expression profiling reveals hepsin overexpression in prostate cancer. Cancer Res 61:5692-5696
-
(2001)
Cancer Res
, vol.61
, pp. 5692-5696
-
-
Magee, J.A.1
Araki, T.2
Patil, S.3
Ehrig, T.4
True, L.5
Humphrey, P.A.6
Catalona, W.J.7
Watson, M.A.8
Milbrandt, J.9
-
199
-
-
0034725119
-
Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells
-
Mai J, Finley RL Jr, Waisman DM, Sloane BF (2000) Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells. J Biol Chem 275:12806-12812
-
(2000)
J Biol Chem
, vol.275
, pp. 12806-12812
-
-
Mai, J.1
Finley, R.L.2
Waisman, D.M.3
Sloane, B.F.4
-
200
-
-
0035921821
-
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase
-
Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts JM (2001) A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase. Nature 413:323-327
-
(2001)
Nature
, vol.413
, pp. 323-327
-
-
Malek, N.P.1
Sundberg, H.2
McGrew, S.3
Nakayama, K.4
Kyriakides, T.R.5
Roberts, J.M.6
-
201
-
-
78149447767
-
Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas
-
Malla R, Gopinath S, Alapati K, Gondi CS, Gujrati M, Dinh DH, Mohanam S, Rao JS (2010) Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas. PLoS One 5:e13731
-
(2010)
PLoS One
, vol.5
, pp. e13731
-
-
Malla, R.1
Gopinath, S.2
Alapati, K.3
Gondi, C.S.4
Gujrati, M.5
Dinh, D.H.6
Mohanam, S.7
Rao, J.S.8
-
202
-
-
79956136629
-
Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma
-
Malla RR, Gopinath S, Gondi CS, Alapati K, Dinh DH, Gujrati M, Rao JS (2011) Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma. Cancer Gene Ther 18:419-434
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 419-434
-
-
Malla, R.R.1
Gopinath, S.2
Gondi, C.S.3
Alapati, K.4
Dinh, D.H.5
Gujrati, M.6
Rao, J.S.7
-
203
-
-
84861693061
-
UPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma
-
Malla RR, Gopinath S, Gondi CS, Alapati K, Dinh DH, Tsung AJ, Rao JS (2012) uPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma. J Neurooncol 107:69-80
-
(2012)
J Neurooncol
, vol.107
, pp. 69-80
-
-
Malla, R.R.1
Gopinath, S.2
Gondi, C.S.3
Alapati, K.4
Dinh, D.H.5
Tsung, A.J.6
Rao, J.S.7
-
204
-
-
14944343729
-
Hypermethylation of the 50 CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis
-
Manton KJ, Douglas ML, Netzel-Arnett S, Fitzpatrick DR, Nicol DL, Boyd AW, Clements JA, Antalis TM (2005) Hypermethylation of the 50 CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis. Br J Cancer 92:760-769
-
(2005)
Br J Cancer
, vol.92
, pp. 760-769
-
-
Manton, K.J.1
Douglas, M.L.2
Netzel-Arnett, S.3
Fitzpatrick, D.R.4
Nicol, D.L.5
Boyd, A.W.6
Clements, J.A.7
Antalis, T.M.8
-
205
-
-
34547132328
-
Tissuespecific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C (2007) Tissuespecific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 282:18573-18583
-
(2007)
J Biol Chem
, vol.282
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
207
-
-
56249125301
-
Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma
-
Marten A, Zeiss N, Serba S, Mehrle S, von Lilienfeld-Toal M, Schmidt J (2008) Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma. Mol Cancer Ther 7:3624-3631
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3624-3631
-
-
Marten, A.1
Zeiss, N.2
Serba, S.3
Mehrle, S.4
Von Lilienfeld-Toal, M.5
Schmidt, J.6
-
208
-
-
51049100625
-
Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background
-
Martin MD, Carter KJ, Jean-Philippe SR, Chang M, Mobashery S, .Thiolloy S, Lynch CC, Matrisian LM, Fingleton B (2008) Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background. Cancer Res 68:6251-6259
-
(2008)
Cancer Res
, vol.68
, pp. 6251-6259
-
-
Martin, M.D.1
Carter, K.J.2
Jean-Philippe, S.R.3
Chang, M.4
Mobashery, S.5
Thiolloy, S.6
Lynch, C.C.7
Matrisian, L.M.8
Fingleton, B.9
-
209
-
-
78649560431
-
Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor
-
Masset A, Maillard C, Sounni NE, Jacobs N, Bruyere F, Delvenne P, Tacke M, Reinheckel T, Foidart J-M, Coussens LM, Noel A (2011) Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. Int J Cancer 128:283-293
-
(2011)
Int J Cancer
, vol.128
, pp. 283-293
-
-
Masset, A.1
Maillard, C.2
Sounni, N.E.3
Jacobs, N.4
Bruyere, F.5
Delvenne, P.6
Tacke, M.7
Reinheckel, T.8
Foidart, J.-M.9
Coussens, L.M.10
Noel, A.11
-
210
-
-
0032559821
-
In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy
-
Masson R, Lefebvre O, Noel A, Fahime ME, Chenard MP, Wendling C, Kebers F, LeMeur M, Dierich A, Foidart JM, Basset P, Rio MC (1998) In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J Cell Biol 140:1535-1541
-
(1998)
J Cell Biol
, vol.140
, pp. 1535-1541
-
-
Masson, R.1
Lefebvre, O.2
Noel, A.3
Fahime, M.E.4
Chenard, M.P.5
Wendling, C.6
Kebers, F.7
Lemeur, M.8
Dierich, A.9
Foidart, J.M.10
Basset, P.11
Rio, M.C.12
-
211
-
-
77950356821
-
Proteasome inhibitor MG132 inhibits angiogenesis in pancreatic cancer by blocking NF-kappaB activity
-
Matsuo Y, Sawai H, Ochi N, Yasuda A, Sakamoto M, Takahashi H, Funahashi H, Takeyama H, Guha S (2010) Proteasome inhibitor MG132 inhibits angiogenesis in pancreatic cancer by blocking NF-kappaB activity. Dig Dis Sci 55:1167-1176
-
(2010)
Dig Dis Sci
, vol.55
, pp. 1167-1176
-
-
Matsuo, Y.1
Sawai, H.2
Ochi, N.3
Yasuda, A.4
Sakamoto, M.5
Takahashi, H.6
Funahashi, H.7
Takeyama, H.8
Guha, S.9
-
213
-
-
4944235417
-
A protective role for matrix metalloproteinase-3 in squamous cell carcinoma
-
McCawley LJ, Crawford HC, King LE Jr, Mudgett J, Matrisian LM (2004) A protective role for matrix metalloproteinase-3 in squamous cell carcinoma. Cancer Res 64:6965-6972
-
(2004)
Cancer Res
, vol.64
, pp. 6965-6972
-
-
McCawley, L.J.1
Crawford, H.C.2
King, L.E.3
Mudgett, J.4
Matrisian, L.M.5
-
214
-
-
55349131011
-
Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishment
-
McCawley LJ, Wright J, LaFleur BJ, Crawford HC, Matrisian LM (2008) Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishment. Am J Pathol 173:1528-1539
-
(2008)
Am J Pathol
, vol.173
, pp. 1528-1539
-
-
McCawley, L.J.1
Wright, J.2
Lafleur, B.J.3
Crawford, H.C.4
Matrisian, L.M.5
-
215
-
-
45849152092
-
A novel role for a familiar protein in apoptosis induced by proteasome inhibition
-
McConkey DJ (2008) A novel role for a familiar protein in apoptosis induced by proteasome inhibition. Cancer Cell 14:1-2
-
(2008)
Cancer Cell
, vol.14
, pp. 1-2
-
-
McConkey, D.J.1
-
216
-
-
53049083867
-
Mechanisms of proteasome inhibitor action and resistance in cancer
-
McConkey DJ, Zhu K (2008) Mechanisms of proteasome inhibitor action and resistance in cancer. Drug Resist Updat 11:164-179
-
(2008)
Drug Resist Updat
, vol.11
, pp. 164-179
-
-
McConkey, D.J.1
Zhu, K.2
-
217
-
-
79953859157
-
Cancer therapy based on oncogene addiction
-
McCormick F (2011) Cancer therapy based on oncogene addiction. J Surg Oncol 103:464-467
-
(2011)
J Surg Oncol
, vol.103
, pp. 464-467
-
-
McCormick, F.1
-
218
-
-
0344874727
-
Molecular imaging of proteolytic activity in cancer
-
McIntyre JO, Matrisian LM (2003) Molecular imaging of proteolytic activity in cancer. J Cell Biochem 90:1087-1097
-
(2003)
J Cell Biochem
, vol.90
, pp. 1087-1097
-
-
McIntyre, J.O.1
Matrisian, L.M.2
-
219
-
-
77950346680
-
Near-infrared optical proteolytic beacons for in vivo imaging of matrix metalloproteinase activity
-
McIntyre JO, Scherer RL, Matrisian LM (2010) Near-infrared optical proteolytic beacons for in vivo imaging of matrix metalloproteinase activity. Methods Mol Biol 622:279-304
-
(2010)
Methods Mol Biol
, vol.622
, pp. 279-304
-
-
McIntyre, J.O.1
Scherer, R.L.2
Matrisian, L.M.3
-
220
-
-
0037103183
-
Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo
-
McQuibban GA, Gong JH, Wong JP, Wallace JL, Clark-Lewis I, Overall CM (2002) Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood 100:1160-1167
-
(2002)
Blood
, vol.100
, pp. 1160-1167
-
-
McQuibban, G.A.1
Gong, J.H.2
Wong, J.P.3
Wallace, J.L.4
Clark-Lewis, I.5
Overall, C.M.6
-
221
-
-
62449313467
-
Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells
-
Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J (2009) Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells. Cancer Res 69:1976-1984
-
(2009)
Cancer Res
, vol.69
, pp. 1976-1984
-
-
Meissner, M.1
Reichenbach, G.2
Stein, M.3
Hrgovic, I.4
Kaufmann, R.5
Gille, J.6
-
222
-
-
80052587306
-
Ferriliposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment
-
Mikhaylov G, Mikac U, Magaeva AA, Itin VI, Naiden EP, Psakhye I, Babes L, Reinheckel T, Peters C, Zeiser R, Bogyo M, Turk V, Psakhye SG, Turk B, Vasiljeva O (2011) Ferriliposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat Nanotechnol 6:594-602
-
(2011)
Nat Nanotechnol
, vol.6
, pp. 594-602
-
-
Mikhaylov, G.1
Mikac, U.2
Magaeva, A.A.3
Itin, V.I.4
Naiden, E.P.5
Psakhye, I.6
Babes, L.7
Reinheckel, T.8
Peters, C.9
Zeiser, R.10
Bogyo, M.11
Turk, V.12
Psakhye, S.G.13
Turk, B.14
Vasiljeva, O.15
-
223
-
-
0032917409
-
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1
-
Mikolajczyk SD, Millar LS, Kumar A, Saedi MS (1999) Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1. Int J Cancer 81:438-442
-
(1999)
Int J Cancer
, vol.81
, pp. 438-442
-
-
Mikolajczyk, S.D.1
Millar, L.S.2
Kumar, A.3
Saedi, M.S.4
-
224
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
Mohamed MM, Sloane BF (2006) Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer 6:764-775
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
225
-
-
77952483919
-
Fluorescent imaging of tumors
-
Shields A, Price P (eds Humana, Totawa
-
Moin K, McIntyre OJ, Matrisian LM, Sloane BF (2007) Fluorescent imaging of tumors. In: Shields A, Price P (eds) In vivo imaging of cancer therapy. Humana, Totawa, pp 281-302
-
(2007)
Vivo Imaging of Cancer Therapy
, pp. 281-302
-
-
Moin, K.1
McIntyre, O.J.2
Matrisian, L.M.3
Sloane, B.F.4
-
226
-
-
84857282245
-
3D/4D functional imaging of tumor-Associated proteolysis: Impact of microenvironment
-
Moin K, Sameni M, Victor BC, Rothberg JM, Mattingly RR, Sloane BF (2012) 3D/4D functional imaging of tumor-Associated proteolysis: impact of microenvironment. Methods Enzymol 506:175-194
-
(2012)
Methods Enzymol
, vol.506
, pp. 175-194
-
-
Moin, K.1
Sameni, M.2
Victor, B.C.3
Rothberg, J.M.4
Mattingly, R.R.5
Sloane, B.F.6
-
227
-
-
0035802183
-
Prostasin, a potential serum marker for ovarian cancer: Identification through microarray technology
-
Mok SC, Chao J, Skates S, Wong KK, Yiu GK, Muto MG, Berkowitz RS, Cramer DW (2001) Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology. J Natl Cancer Inst 93:1458-1464
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1458-1464
-
-
Mok, S.C.1
Chao, J.2
Skates, S.3
Wong, K.K.4
Yiu, G.K.5
Muto, M.G.6
Berkowitz, R.S.7
Cramer, D.W.8
-
228
-
-
79959709904
-
Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form
-
Mongaret C, Alexandre J, Thomas-Schoemann A, Bermudez E, Chereau C, Nicco C, Goldwasser F, Weill B, Batteux F, Lemare F (2011) Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form. Int J Cancer 129:791-798
-
(2011)
Int J Cancer
, vol.129
, pp. 791-798
-
-
Mongaret, C.1
Alexandre, J.2
Thomas-Schoemann, A.3
Bermudez, E.4
Chereau, C.5
Nicco, C.6
Goldwasser, F.7
Weill, B.8
Batteux, F.9
Lemare, F.10
-
229
-
-
33750156940
-
Pro-urokinase-Type plasminogen activator is a substrate for hepsin
-
Moran P, Li W, Fan B, Vij R, Eigenbrot C, Kirchhofer D (2006) Pro-urokinase-Type plasminogen activator is a substrate for hepsin. J Biol Chem 281:30439-30446
-
(2006)
J Biol Chem
, vol.281
, pp. 30439-30446
-
-
Moran, P.1
Li, W.2
Fan, B.3
Vij, R.4
Eigenbrot, C.5
Kirchhofer, D.6
-
230
-
-
77950103929
-
Self-Assembled gold nanoparticle molecular probes for detecting proteolytic activity in vivo
-
Mu CJ, Lavan DA, Langer RS, Zetter BR (2010) Self-Assembled gold nanoparticle molecular probes for detecting proteolytic activity in vivo. ACS Nano 4:1511-1520
-
(2010)
ACS Nano
, vol.4
, pp. 1511-1520
-
-
Mu, C.J.1
Lavan, D.A.2
Langer, R.S.3
Zetter, B.R.4
-
231
-
-
56749133149
-
The ADAMs: Signalling scissors in the tumour microenvironment
-
Murphy G (2008) The ADAMs: signalling scissors in the tumour microenvironment. Nat Rev Cancer 8:929-941
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 929-941
-
-
Murphy, G.1
-
232
-
-
42949161079
-
Use of the HESI Admission Assessment to predict student success
-
Murray KT, Merriman CS, Adamson C (2008) Use of the HESI Admission Assessment to predict student success. Comput Inform Nurs 26:61S-66S
-
(2008)
Comput Inform Nurs
, vol.26
, pp. 61S-66S
-
-
Murray, K.T.1
Merriman, C.S.2
Adamson, C.3
-
233
-
-
73649133630
-
Novel TACE inhibitors in drug discovery: A review of patented compounds
-
Murumkar PR, DasGupta S, Chandani SR, Giridhar R, Yadav MR (2010) Novel TACE inhibitors in drug discovery: a review of patented compounds. Expert Opin Ther Pat 20:31-57
-
(2010)
Expert Opin Ther Pat
, vol.20
, pp. 31-57
-
-
Murumkar, P.R.1
Dasgupta, S.2
Chandani, S.R.3
Giridhar, R.4
Yadav, M.R.5
-
234
-
-
79953324956
-
The role of hepatocyte growth factor activator inhibitor (HAI)-1 and HAI-2 in endometrial cancer
-
Nakamura K, Hongo A, Kodama J, Hiramatsu Y (2011) The role of hepatocyte growth factor activator inhibitor (HAI)-1 and HAI-2 in endometrial cancer. Int J Cancer 128:2613-2624
-
(2011)
Int J Cancer
, vol.128
, pp. 2613-2624
-
-
Nakamura, K.1
Hongo, A.2
Kodama, J.3
Hiramatsu, Y.4
-
235
-
-
77955920079
-
Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells
-
Nalla AK, Gorantla B, Gondi CS, Lakka SS, Rao JS (2010) Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells. Cancer Gene Ther 17:599-613
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 599-613
-
-
Nalla, A.K.1
Gorantla, B.2
Gondi, C.S.3
Lakka, S.S.4
Rao, J.S.5
-
236
-
-
0037688169
-
Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer
-
Netzel-Arnett S, Hooper JD, Szabo R, Madison EL, Quigley JP, Bugge TH, Antalis AM (2003) Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Rev 22:237-258
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 237-258
-
-
Netzel-Arnett, S.1
Hooper, J.D.2
Szabo, R.3
Madison, E.L.4
Quigley, J.P.5
Bugge, T.H.6
Antalis, A.M.7
-
237
-
-
77749254873
-
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
-
Nguyen QT, Olson ES, Aguilera TA, Jiang T, Scadeng M, Ellies LG, Tsien RY (2010) Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci U S A 107:4317-4322
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4317-4322
-
-
Nguyen, Q.T.1
Olson, E.S.2
Aguilera, T.A.3
Jiang, T.4
Scadeng, M.5
Ellies, L.G.6
Tsien, R.Y.7
-
238
-
-
45849099115
-
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition
-
Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sorensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gutgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP (2008) Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell 14:23-35
-
(2008)
Cancer Cell
, vol.14
, pp. 23-35
-
-
Nickeleit, I.1
Zender, S.2
Sasse, F.3
Geffers, R.4
Brandes, G.5
Sorensen, I.6
Steinmetz, H.7
Kubicka, S.8
Carlomagno, T.9
Menche, D.10
Gutgemann, I.11
Buer, J.12
Gossler, A.13
Manns, M.P.14
Kalesse, M.15
Frank, R.16
Malek, N.P.17
-
239
-
-
51849083879
-
Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression
-
Nielsen BS, Egeblad M, Rank F, Askautrud HA, Pennington CJ, Pedersen TX, Christensen IJ, Edwards DR, Werb Z, Lund LR (2008) Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PLoS One 3:e2959
-
(2008)
PLoS One
, vol.3
, pp. e2959
-
-
Nielsen, B.S.1
Egeblad, M.2
Rank, F.3
Askautrud, H.A.4
Pennington, C.J.5
Pedersen, T.X.6
Christensen, I.J.7
Edwards, D.R.8
Werb, Z.9
Lund, L.R.10
-
240
-
-
79954990288
-
Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs
-
Obaidat A, Weiss J, Wahlgren B, Manam RR, Macherla VR, McArthur K, Chao TH, Palladino MA, Lloyd GK, Potts BC, Enna SJ, Neuteboom ST, Hagenbuch B (2011) Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs. J Pharmacol Exp Ther 337:479-486
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 479-486
-
-
Obaidat, A.1
Weiss, J.2
Wahlgren, B.3
Manam, R.R.4
MacHerla, V.R.5
McArthur, K.6
Chao, T.H.7
Palladino, M.A.8
Lloyd, G.K.9
Potts, B.C.10
Enna, S.J.11
Neuteboom, S.T.12
Hagenbuch, B.13
-
241
-
-
0036554846
-
Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: Correlation with clinical outcome and tumor clinicopathological parameters
-
Oberst MD, Johnson MD, Dickson RB, Lin CY, Singh B, Stewart M, Williams A, al-Nafussi A, Smyth JF, Gabra H, Sellar GC (2002) Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: Correlation with clinical outcome and tumor clinicopathological parameters. Clin Cancer Res 8:1101-1107
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1101-1107
-
-
Oberst, M.D.1
Johnson, M.D.2
Dickson, R.B.3
Lin, C.Y.4
Singh, B.5
Stewart, M.6
Williams, A.7
Al-Nafussi, A.8
Smyth, J.F.9
Gabra, H.10
Sellar, G.C.11
-
242
-
-
75149115745
-
Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice
-
Ogden SR, Noto JM, Allen SS, Patel DA, Romero-Gallo J, Washington MK, Fingleton B, Israel DA, Lewis ND, Wilson KT, Chaturvedi R, Zhao Z, Shyr Y, Peek RM Jr (2010) Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice. Cancer Res 70:30-35
-
(2010)
Cancer Res
, vol.70
, pp. 30-35
-
-
Ogden, S.R.1
Noto, J.M.2
Allen, S.S.3
Patel, D.A.4
Romero-Gallo, J.5
Washington, M.K.6
Fingleton, B.7
Israel, D.A.8
Lewis, N.D.9
Wilson, K.T.10
Chaturvedi, R.11
Zhao, Z.12
Shyr, Y.13
Peek, R.M.14
-
243
-
-
0032495977
-
The proteasome is involved in angiogenesis
-
Oikawa T, Sasaki T, Nakamura M, Shimamura M, Tanahashi N, Omura S, Tanaka K (1998) The proteasome is involved in angiogenesis. Biochem Biophys Res Commun 246:243-248
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 243-248
-
-
Oikawa, T.1
Sasaki, T.2
Nakamura, M.3
Shimamura, M.4
Tanahashi, N.5
Omura, S.6
Tanaka, K.7
-
244
-
-
77749297971
-
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
-
Olson ES, Jiang T, Aguilera TA, Nguyen QT, Ellies LG, Scadeng M, Tsien RY (2010) Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A 107:4311-4316
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4311-4316
-
-
Olson, E.S.1
Jiang, T.2
Aguilera, T.A.3
Nguyen, Q.T.4
Ellies, L.G.5
Scadeng, M.6
Tsien, R.Y.7
-
245
-
-
78049463805
-
Future directions of bonetargeted therapy for metastatic breast cancer
-
Onishi T, Hayashi N, Theriault RL, Hortobagyi GN, Ueno NT (2010) Future directions of bonetargeted therapy for metastatic breast cancer. Nat Rev Clin Oncol 7:641-651
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 641-651
-
-
Onishi, T.1
Hayashi, N.2
Theriault, R.L.3
Hortobagyi, G.N.4
Ueno, N.T.5
-
247
-
-
42249109450
-
Serine peptidases: Classification, structure and function
-
Page MJ, Di Cera E (2008) Serine peptidases: classification, structure and function. Cell Mol Life Sci 65:1220-1236
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1220-1236
-
-
Page, M.J.1
Di Cera, E.2
-
248
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-Treated, node-negative breast cancer
-
Paik S, Shak S, Tang G, Kim C, Baker J, Cronin M, Baehner FL, Walker MG, Watson D, Park T, Hiller W, Fisher ER, Wickerham DL, Bryant J, Wolmark N (2004) A multigene assay to predict recurrence of tamoxifen-Treated, node-negative breast cancer. N Engl J Med 351:2817-2826
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
Kim, C.4
Baker, J.5
Cronin, M.6
Baehner, F.L.7
Walker, M.G.8
Watson, D.9
Park, T.10
Hiller, W.11
Fisher, E.R.12
Wickerham, D.L.13
Bryant, J.14
Wolmark, N.15
-
249
-
-
67349149403
-
Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma
-
Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, Filie AC, O'Connell MP, Banister CE, Howard JD, Buckhaults P, Weeraratna AT, Brody LC, Rosenberg SA, Samuels Y (2009) Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nat Genet 41:518-520
-
(2009)
Nat Genet
, vol.41
, pp. 518-520
-
-
Palavalli, L.H.1
Prickett, T.D.2
Wunderlich, J.R.3
Wei, X.4
Burrell, A.S.5
Porter-Gill, P.6
Davis, S.7
Wang, C.8
Cronin, J.C.9
Agrawal, N.S.10
Lin, J.C.11
Westbroek, W.12
Hoogstraten-Miller, S.13
Molinolo, A.A.14
Fetsch, P.15
Filie, A.C.16
O'connell, M.P.17
Banister, C.E.18
Howard, J.D.19
Buckhaults, P.20
Weeraratna, A.T.21
Brody, L.C.22
Rosenberg, S.A.23
Samuels, Y.24
more..
-
250
-
-
33947224164
-
Human tissue kallikreins: The cancer biomarker family
-
Paliouras M, Borgono C, Diamandis EP (2007) Human tissue kallikreins: the cancer biomarker family. Cancer Lett 249:61-79
-
(2007)
Cancer Lett
, vol.249
, pp. 61-79
-
-
Paliouras, M.1
Borgono, C.2
Diamandis, E.P.3
-
251
-
-
63849329963
-
Cathepsin S and its inhibitor cystatin C: Imbalance in uveal melanoma
-
Paraoan L, Gray D, Hiscott P, Garcia-Finana M, Lane B, Damato B, Grierson I (2009) Cathepsin S and its inhibitor cystatin C: imbalance in uveal melanoma. Front Biosci 14:2504-2513
-
(2009)
Front Biosci
, vol.14
, pp. 2504-2513
-
-
Paraoan, L.1
Gray, D.2
Hiscott, P.3
Garcia-Finana, M.4
Lane, B.5
Damato, B.6
Grierson, I.7
-
252
-
-
3543134126
-
Matrix metalloproteinases as modulators of inflammation and innate immunity
-
Parks WC, Wilson CL, Lopez-Boado YS (2004) Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 4:617-629
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 617-629
-
-
Parks, W.C.1
Wilson, C.L.2
Lopez-Boado, Y.S.3
-
253
-
-
2942629103
-
Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice
-
Pendas AM, Folgueras AR, Llano E, Caterina J, Frerard F, Rodriguez F, Astudillo A, Noel A, Birkedal-Hansen H, Lopez-Otin C (2004) Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice. Mol Cell Biol 24:5304-5313
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5304-5313
-
-
Pendas, A.M.1
Folgueras, A.R.2
Llano, E.3
Caterina, J.4
Frerard, F.5
Rodriguez, F.6
Astudillo, A.7
Noel, A.8
Birkedal-Hansen, H.9
Lopez-Otin, C.10
-
255
-
-
70349241644
-
Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis
-
Podgorski I, Linebaugh BE, Koblinski JE, Rudy DL, Herroon MK, Olive MB, Sloane BF (2009) Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. Am J Pathol 175:1255-1269
-
(2009)
Am J Pathol
, vol.175
, pp. 1255-1269
-
-
Podgorski, I.1
Linebaugh, B.E.2
Koblinski, J.E.3
Rudy, D.L.4
Herroon, M.K.5
Olive, M.B.6
Sloane, B.F.7
-
256
-
-
52649090735
-
Urinary metalloproteinases: Noninvasive biomarkers for breast cancer risk assessment
-
Pories SE, Zurakowski D, Roy R, Lamb CC, Raza S, Exarhopoulos A, Scheib RG, Schumer S, Lenahan C, Borges V, Louis GW, Anand A, Isakovich N, Hirshfield-Bartek J, Wewer U, Lotz MM, Moses MA (2008) Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment. Cancer Epidemiol Biomarkers Prev 17:1034-1042
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 1034-1042
-
-
Pories, S.E.1
Zurakowski, D.2
Roy, R.3
Lamb, C.C.4
Raza, S.5
Exarhopoulos, A.6
Scheib, R.G.7
Schumer, S.8
Lenahan, C.9
Borges, V.10
Louis, G.W.11
Anand, A.12
Isakovich, N.13
Hirshfield-Bartek, J.14
Wewer, U.15
Lotz, M.M.16
Moses, M.A.17
-
257
-
-
79951684725
-
Marizomib, a proteasome inhibitor for all seasons: Preclinical profile and a framework for clinical trials
-
Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC Jr, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller C, Neuteboom STC, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA (2011) Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets 11:254-284
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 254-284
-
-
Potts, B.C.1
Albitar, M.X.2
Anderson, K.C.3
Baritaki, S.4
Berkers, C.5
Bonavida, B.6
Chandra, J.7
Chauhan, D.8
Cusack, J.C.9
Fenical, W.10
Ghobrial, I.M.11
Groll, M.12
Jensen, P.R.13
Lam, K.S.14
Lloyd, G.K.15
McBride, W.16
McConkey, D.J.17
Miller, C.18
Neuteboom, S.T.C.19
Oki, Y.20
Ovaa, H.21
Pajonk, F.22
Richardson, P.G.23
Roccaro, A.M.24
Sloss, C.M.25
Spear, M.A.26
Valashi, E.27
Younes, A.28
Palladino, M.A.29
more..
-
258
-
-
78649855179
-
A new nuclear protease with cathepsin L properties is present in HeLa and Caco-2 cells
-
Puchi M, Garcia-Huidobro J, Cordova C, Aguilar R, Dufey E, Imschenetzky M, Bustos P, Morin V (2010) A new nuclear protease with cathepsin L properties is present in HeLa and Caco-2 cells. J Cell Biochem 111:1099-1106
-
(2010)
J Cell Biochem
, vol.111
, pp. 1099-1106
-
-
Puchi, M.1
Garcia-Huidobro, J.2
Cordova, C.3
Aguilar, R.4
Dufey, E.5
Imschenetzky, M.6
Bustos, P.7
Morin, V.8
-
260
-
-
18044373469
-
A genomic view of the complexity of mammalian proteolytic systems
-
Puente XS, Sanchez LM, Gutierrez-Fernandez A, Velasco G, Lopez-Otin C (2005) A genomic view of the complexity of mammalian proteolytic systems. Biochem Soc Trans 33:331-334
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 331-334
-
-
Puente, X.S.1
Sanchez, L.M.2
Gutierrez-Fernandez, A.3
Velasco, G.4
Lopez-Otin, C.5
-
261
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW (2010) Macrophage diversity enhances tumor progression and metastasis. Cell 141:39-51
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
262
-
-
70349737818
-
Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition
-
Qu P, Du H, Wang X, Yan C (2009) Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition. Cancer Res 69:7252-7261
-
(2009)
Cancer Res
, vol.69
, pp. 7252-7261
-
-
Qu, P.1
Du, H.2
Wang, X.3
Yan, C.4
-
263
-
-
49549102043
-
Cathepsin K in melanoma invasion
-
Quintanilla-Dieck MJ, Codriansky K, Keady M, Bhawan J, Runger TM (2008) Cathepsin K in melanoma invasion. J Invest Dermatol 128:2281-2288
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2281-2288
-
-
Quintanilla-Dieck, M.J.1
Codriansky, K.2
Keady, M.3
Bhawan, J.4
Runger, T.M.5
-
264
-
-
84859796622
-
Novel therapies in benign and malignant bone diseases
-
Rachner TD, Hadji P, Hofbauer LC (2012) Novel therapies in benign and malignant bone diseases. Pharmacol Ther 134:338-344
-
(2012)
Pharmacol Ther
, vol.134
, pp. 338-344
-
-
Rachner, T.D.1
Hadji, P.2
Hofbauer, L.C.3
-
265
-
-
21844432918
-
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
-
Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA, Werb Z, Bissell MJ (2005) Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 436:123-127
-
(2005)
Nature
, vol.436
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
Werb, Z.11
Bissell, M.J.12
-
266
-
-
84859085199
-
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression
-
Rafn B, Nielsen CF, Andersen SH, Szyniarowski P, Corcelle-Termeau E, Valo E, Fehrenbacher N, Olsen CJ, Daugaard M, Egebjerg C, Bottzauw T, Kohonen P, Nylandsted J, Hautaniemi S, Moreira J, Jaattela M, Kallunki T (2012) ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression. Mol Cell 45:764-776
-
(2012)
Mol Cell
, vol.45
, pp. 764-776
-
-
Rafn, B.1
Nielsen, C.F.2
Andersen, S.H.3
Szyniarowski, P.4
Corcelle-Termeau, E.5
Valo, E.6
Fehrenbacher, N.7
Olsen, C.J.8
Daugaard, M.9
Egebjerg, C.10
Bottzauw, T.11
Kohonen, P.12
Nylandsted, J.13
Hautaniemi, S.14
Moreira, J.15
Jaattela, M.16
Kallunki, T.17
-
267
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: The role of proteases
-
Rao JS (2003) Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 3:489-501
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 489-501
-
-
Rao, J.S.1
-
268
-
-
84884816982
-
Knockdown of cathepsin B and uPAR inhibits CD151 and alpha3beta1 integrin-mediated cell adhesion and invasion in glioma
-
doi:10.1002/mc.21915
-
Rao Malla R, Gopinath S, Alapati K, Gorantla B, Gondi CS, Rao JS (2012) Knockdown of cathepsin B and uPAR inhibits CD151 and alpha3beta1 integrin-mediated cell adhesion and invasion in glioma. Mol Carcinog. doi:10.1002/mc.21915
-
(2012)
Mol Carcinog.
-
-
Rao Malla, R.1
Gopinath, S.2
Alapati, K.3
Gorantla, B.4
Gondi, C.S.5
Rao, J.S.6
-
269
-
-
33744502621
-
Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma. A useful marker of invasive growth
-
Rapa I, Volante M, Cappia S, Rosas R, Scagliotti GV, Papotti M (2006) Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma. A useful marker of invasive growth. Am J Clin Pathol 125:847-854
-
(2006)
Am J Clin Pathol
, vol.125
, pp. 847-854
-
-
Rapa, I.1
Volante, M.2
Cappia, S.3
Rosas, R.4
Scagliotti, G.V.5
Papotti, M.6
-
270
-
-
0027479821
-
Evolutionary families of peptidases
-
Rawlings ND, Barrett AJ (1993) Evolutionary families of peptidases. Biochem J 290 (Pt 1):205-218
-
(1993)
Biochem J
, vol.290
, pp. 205-218
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
272
-
-
77957855881
-
Specialized roles for cysteine cathepsins in health and disease
-
Reiser J, Adair B, Reinheckel T (2010) Specialized roles for cysteine cathepsins in health and disease. J Clin Invest 120:3421-3431
-
(2010)
J Clin Invest
, vol.120
, pp. 3421-3431
-
-
Reiser, J.1
Adair, B.2
Reinheckel, T.3
-
273
-
-
67650620318
-
Regulation and cellular roles of ubiquitinspecific deubiquitinating enzymes
-
Reyes-Turcu FE, Ventii KH, Wilkinson KD (2009) Regulation and cellular roles of ubiquitinspecific deubiquitinating enzymes. Annu Rev Biochem 78:363-397
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
274
-
-
61649113720
-
Endogenous inhibitors of angiogenesis: A historical review
-
Ribatti D (2009) Endogenous inhibitors of angiogenesis: a historical review. Leuk Res 33:638-644
-
(2009)
Leuk Res
, vol.33
, pp. 638-644
-
-
Ribatti, D.1
-
275
-
-
56449098781
-
ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo
-
Rocks N, Paulissen G, Quesada-Calvo F, Munaut C, Gonzalez ML, Gueders M, Hacha J, Gilles C, Foidart JM, Noel A, Cataldo DD (2008) ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo. Cancer Res 68:9541-9550
-
(2008)
Cancer Res
, vol.68
, pp. 9541-9550
-
-
Rocks, N.1
Paulissen, G.2
Quesada-Calvo, F.3
Munaut, C.4
Gonzalez, M.L.5
Gueders, M.6
Hacha, J.7
Gilles, C.8
Foidart, J.M.9
Noel, A.10
Cataldo, D.D.11
-
276
-
-
77957809884
-
ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties
-
Rose AA, Annis MG, Dong Z, Pepin F, Hallett M, Park M, Siegel PM (2010) ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties. PLoS One 5:e12093
-
(2010)
PLoS One
, vol.5
, pp. e12093
-
-
Rose, A.A.1
Annis, M.G.2
Dong, Z.3
Pepin, F.4
Hallett, M.5
Park, M.6
Siegel, P.M.7
-
277
-
-
0032403129
-
The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis
-
Rudolph-Owen LA, Chan R, Muller WJ, Matrisian LM (1998) The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Cancer Res 58:5500-5506
-
(1998)
Cancer Res
, vol.58
, pp. 5500-5506
-
-
Rudolph-Owen, L.A.1
Chan, R.2
Muller, W.J.3
Matrisian, L.M.4
-
278
-
-
84885337942
-
Cathepsin C is a tissue-specific regulator of squamous carcinogenesis
-
in press
-
Ruffell B, Affara NI, Cottone L, Junankar S, Johansson M, DeNardo DG, Korets L, Reinheckel T, Sloane BF, Bogyo M, Coussens LM (2013) Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. Genes Dev (in press
-
(2013)
Genes Dev.
-
-
Ruffell, B.1
Affara, N.I.2
Cottone, L.3
Junankar, S.4
Johansson, M.5
Denardo, D.G.6
Korets, L.7
Reinheckel, T.8
Sloane, B.F.9
Bogyo, M.10
Coussens, L.M.11
-
279
-
-
0142084471
-
Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes
-
Rumpler G, Becker B, Hafner C, McClelland M, Stolz W, Landthaler M, Schmitt R, Bosserhoff A, Vogt T (2003) Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes. Exp Dermatol 12:761-771
-
(2003)
Exp Dermatol
, vol.12
, pp. 761-771
-
-
Rumpler, G.1
Becker, B.2
Hafner, C.3
McClelland, M.4
Stolz, W.5
Landthaler, M.6
Schmitt, R.7
Bosserhoff, A.8
Vogt, T.9
-
280
-
-
9444290419
-
Tumor cell traffic through the extracellular matrix is controlled by the membrane-Anchored collagenase MT1-MMP
-
Sabeh F, Ota I, Holmbeck K, Birkedal-Hansen H, Soloway P, Balbin M, Lopez-Otin C, Shapiro S, Inada M, Krane S, Allen E, Chung D, Weiss SJ (2004) Tumor cell traffic through the extracellular matrix is controlled by the membrane-Anchored collagenase MT1-MMP. J Cell Biol 167:769-781
-
(2004)
J Cell Biol
, vol.167
, pp. 769-781
-
-
Sabeh, F.1
Ota, I.2
Holmbeck, K.3
Birkedal-Hansen, H.4
Soloway, P.5
Balbin, M.6
Lopez-Otin, C.7
Shapiro, S.8
Inada, M.9
Krane, S.10
Allen, E.11
Chung, D.12
Weiss, S.J.13
-
281
-
-
77949733627
-
Emerging roles of deubiquitinases in cancerassociated pathways
-
Sacco JJ, Coulson JM, Clague MJ, Urbe S (2010) Emerging roles of deubiquitinases in cancerassociated pathways. IUBMB Life 62:140-157
-
(2010)
IUBMB Life
, vol.62
, pp. 140-157
-
-
Sacco, J.J.1
Coulson, J.M.2
Clague, M.J.3
Urbe, S.4
-
282
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-Kdeficient mice
-
Saftig P, Hunziker E, Wehmeyer O, Jones S, Boyde A, Rommerskirch W, Moritz JD, Schu P, von Figura K (1998) Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-Kdeficient mice. Proc Natl Acad Sci U S A 95:13453-13458
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
Jones, S.4
Boyde, A.5
Rommerskirch, W.6
Moritz, J.D.7
Schu, P.8
Von Figura, K.9
-
283
-
-
56649123518
-
Clinical significance of low expression of prostasin mRNA in human gastric cancer
-
Sakashita K, Mimori K, Tanaka F, Tahara K, Inoue H, Sawada T, Ohira M, Hirakawa K, Mori M (2008) Clinical significance of low expression of prostasin mRNA in human gastric cancer. J Surg Oncol 98:559-564
-
(2008)
J Surg Oncol
, vol.98
, pp. 559-564
-
-
Sakashita, K.1
Mimori, K.2
Tanaka, F.3
Tahara, K.4
Inoue, H.5
Sawada, T.6
Ohira, M.7
Hirakawa, K.8
Mori, M.9
-
284
-
-
33644784579
-
A novel biomarker for staging human prostate adenocarcinoma: Overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1
-
Saleem M, Adhami VM, Zhong WX, Longley BJ, Lin CY, Dickson RB, Reagan-Shaw S, Jarrard DF, Mukhtar H (2006) A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1. Cancer Epidemiol Biomarkers Prev 15:217-227
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 217-227
-
-
Saleem, M.1
Adhami, V.M.2
Zhong, W.X.3
Longley, B.J.4
Lin, C.Y.5
Dickson, R.B.6
Reagan-Shaw, S.7
Jarrard, D.F.8
Mukhtar, H.9
-
285
-
-
61549095506
-
Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells
-
Sameni M, Dosescu J, Yamada KM, Sloane BF, Cavallo-Medved D (2008) Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells. Mol Imaging 7:199-213
-
(2008)
Mol Imaging
, vol.7
, pp. 199-213
-
-
Sameni, M.1
Dosescu, J.2
Yamada, K.M.3
Sloane, B.F.4
Cavallo-Medved, D.5
-
286
-
-
0033553419
-
Molecular cloning and structural and functional characterization of human cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain
-
Santamaria I, Velasco G, Pendas AM, Paz A, Lopez-Otin C (1999) Molecular cloning and structural and functional characterization of human cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain. J Biol Chem 274:13800-13809
-
(1999)
J Biol Chem
, vol.274
, pp. 13800-13809
-
-
Santamaria, I.1
Velasco, G.2
Pendas, A.M.3
Paz, A.4
Lopez-Otin, C.5
-
287
-
-
77956215845
-
Rfaut disintegrin and metalloproteinase-10 (ADAM-10) mediates DN30 antibody-induced shedding of the met surface receptor
-
Schelter F, Kobuch J, Moss ML, Becherer JD, Comoglio PM, Boccaccio C, Kruger A (2010) A disintegrin and metalloproteinase-10 (ADAM-10) mediates DN30 antibody-induced shedding of the met surface receptor. J Biol Chem 285:26335-26340
-
(2010)
J Biol Chem
, vol.285
, pp. 26335-26340
-
-
Schelter, F.1
Kobuch, J.2
Moss, M.L.3
Becherer, J.D.4
Comoglio, P.M.5
Boccaccio, C.6
Kruger, A.7
-
289
-
-
61749094550
-
Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon
-
Scherer RL, VanSaun MN, McIntyre JO, Matrisian LM (2008) Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon. Mol Imaging 7:118-131
-
(2008)
Mol Imaging
, vol.7
, pp. 118-131
-
-
Scherer, R.L.1
Vansaun, M.N.2
McIntyre, J.O.3
Matrisian, L.M.4
-
290
-
-
0030857717
-
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: Prognostic relevance and target for therapy
-
Schmitt M, Harbeck N, Thomssen C, Wilhelm O, Magdolen V, Reuning U, Ulm K, Hofler H, Janicke F, Graeff H (1997) Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy. Thromb Haemost 78:285-296
-
(1997)
Thromb Haemost
, vol.78
, pp. 285-296
-
-
Schmitt, M.1
Harbeck, N.2
Thomssen, C.3
Wilhelm, O.4
Magdolen, V.5
Reuning, U.6
Ulm, K.7
Hofler, H.8
Janicke, F.9
Graeff, H.10
-
291
-
-
50849133244
-
Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-Transgenic mouse model
-
Schurigt U, Sevenich L, Vannier C, Gajda M, Schwinde A, Werner F, Stahl A, von Elverfeldt D, Becker AK, Bogyo M, Peters C, Reinheckel T (2008) Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-Transgenic mouse model. Biol Chem 389:1067-1074
-
(2008)
Biol Chem
, vol.389
, pp. 1067-1074
-
-
Schurigt, U.1
Sevenich, L.2
Vannier, C.3
Gajda, M.4
Schwinde, A.5
Werner, F.6
Stahl, A.7
Von Elverfeldt, D.8
Becker, A.K.9
Bogyo, M.10
Peters, C.11
Reinheckel, T.12
-
292
-
-
84892202942
-
Eukaryotic 20S proteasome
-
Barrett AJ, Rawlings ND, Woessner JF (eds vol 2, 2nd edn. Elsevier, London
-
Seemuller E, Dolenc I, Lupas A (2004) Eukaryotic 20S proteasome. In: Barrett AJ, Rawlings ND, Woessner JF (eds) Handbook of proteolytic enzymes, vol 2, 2nd edn. Elsevier, London, pp 2068-2077
-
(2004)
Handbook of Proteolytic Enzymes
, pp. 2068-2077
-
-
Seemuller, E.1
Dolenc, I.2
Lupas, A.3
-
293
-
-
68349152439
-
Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
-
Selzer-Plon J, Bornholdt J, Friis S, Bisgaard HC, Lothe IMB, Tveit KM, Kure EH, Vogel U, Vogel LK (2009) Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis. BMC Cancer 9:201
-
(2009)
BMC Cancer
, vol.9
, pp. 201
-
-
Selzer-Plon, J.1
Bornholdt, J.2
Friis, S.3
Bisgaard, H.C.4
Lothe, I.M.B.5
Tveit, K.M.6
Kure, E.H.7
Vogel, U.8
Vogel, L.K.9
-
294
-
-
78149359763
-
Expression of human cathepsin L or human cathepsin v in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice
-
Sevenich L, Hagemann S, Stoeckle C, Tolosa E, Peters C, Reinheckel T (2010) Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice. Biochimie 92:1674-1680
-
(2010)
Biochimie
, vol.92
, pp. 1674-1680
-
-
Sevenich, L.1
Hagemann, S.2
Stoeckle, C.3
Tolosa, E.4
Peters, C.5
Reinheckel, T.6
-
295
-
-
77249161680
-
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
-
Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Muller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T (2010) Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. Proc Natl Acad Sci U S A 107:2497-2502
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2497-2502
-
-
Sevenich, L.1
Schurigt, U.2
Sachse, K.3
Gajda, M.4
Werner, F.5
Muller, S.6
Vasiljeva, O.7
Schwinde, A.8
Klemm, N.9
Deussing, J.10
Peters, C.11
Reinheckel, T.12
-
296
-
-
74749086987
-
Emerging biological observations in prostate cancer
-
Shah S, Small E (2010) Emerging biological observations in prostate cancer. Expert Rev Anticancer Ther 10:89-101
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 89-101
-
-
Shah, S.1
Small, E.2
-
297
-
-
43149123976
-
The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor
-
Sharghi-Namini S, Fan H, Sulochana KN, Potturi P, Xiang W, Chong YS, Wang Z, Yang H, Ge R (2008) The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor. Biochem Biophys Res Commun 371:215-219
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 215-219
-
-
Sharghi-Namini, S.1
Fan, H.2
Sulochana, K.N.3
Potturi, P.4
Xiang, W.5
Chong, Y.S.6
Wang, Z.7
Yang, H.8
Ge, R.9
-
298
-
-
84873057030
-
Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis
-
Shchors K, Nozawa H, Xu J, Rostker F, Swigart-Brown L, Evan G, Hanahan D (2013) Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis. Oncogene 32(4):502-513
-
(2013)
Oncogene
, vol.32
, Issue.4
, pp. 502-513
-
-
Shchors, K.1
Nozawa, H.2
Xu, J.3
Rostker, F.4
Swigart-Brown, L.5
Evan, G.6
Hanahan, D.7
-
299
-
-
0034599498
-
Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages
-
Shi GP, Bryant RA, Riese R, Verhelst S, Driessen C, Li Z, Bromme D, Ploegh HL, Chapman HA (2000) Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages. J Exp Med 191:1177-1186
-
(2000)
J Exp Med
, vol.191
, pp. 1177-1186
-
-
Shi, G.P.1
Bryant, R.A.2
Riese, R.3
Verhelst, S.4
Driessen, C.5
Li, Z.6
Bromme, D.7
Ploegh, H.L.8
Chapman, H.A.9
-
300
-
-
0033693865
-
Overexpression of testisin, a serine protease expressed by testicular germ cells, in epithelial ovarian tumor cells
-
Shigemasa K, Underwood LJ, Beard J, Tanimoto H, Ohama K, Parmley TH, O'Brien TJ (2000) Overexpression of testisin, a serine protease expressed by testicular germ cells, in epithelial ovarian tumor cells. J Soc Gynecol Investig 7:358-362
-
(2000)
J Soc Gynecol Investig
, vol.7
, pp. 358-362
-
-
Shigemasa, K.1
Underwood, L.J.2
Beard, J.3
Tanimoto, H.4
Ohama, K.5
Parmley, T.H.6
O'brien, T.J.7
-
301
-
-
82955189189
-
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
-
Shree T, Olson OC, Elie BT, Kester JC, Garfall AL, Simpson K, Bell-McGuinn KM, Zabor EC, Brogi E, Joyce JA (2011) Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes Dev 25:2465-2479
-
(2011)
Genes Dev
, vol.25
, pp. 2465-2479
-
-
Shree, T.1
Olson, O.C.2
Elie, B.T.3
Kester, J.C.4
Garfall, A.L.5
Simpson, K.6
Bell-Mcguinn, K.M.7
Zabor, E.C.8
Brogi, E.9
Joyce, J.A.10
-
302
-
-
55649090039
-
Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse
-
Sinnamon MJ, Carter KJ, Fingleton B, Matrisian LM (2008) Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse. Int J Exp Pathol 89:466-475
-
(2008)
Int J Exp Pathol
, vol.89
, pp. 466-475
-
-
Sinnamon, M.J.1
Carter, K.J.2
Fingleton, B.3
Matrisian, L.M.4
-
303
-
-
79551700835
-
ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class i molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers
-
Sinnathamby G, Zerfass J, Hafner J, Block P, Nickens Z, Hobeika A, Secord AA, Lyerly HK, Morse MA, Philip R (2011) ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. Clin Exp Immunol 163:324-332
-
(2011)
Clin Exp Immunol
, vol.163
, pp. 324-332
-
-
Sinnathamby, G.1
Zerfass, J.2
Hafner, J.3
Block, P.4
Nickens, Z.5
Hobeika, A.6
Secord, A.A.7
Lyerly, H.K.8
Morse, M.A.9
Philip, R.10
-
304
-
-
0028273525
-
Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene
-
Sloane BF, Moin K, Sameni M, Tait LR, Rozhin J, Ziegler G (1994) Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene. J Cell Sci 107(Pt 2):373-384
-
(1994)
J Cell Sci
, vol.107
, pp. 373-384
-
-
Sloane, B.F.1
Moin, K.2
Sameni, M.3
Tait, L.R.4
Rozhin, J.5
Ziegler, G.6
-
305
-
-
2942608208
-
Expression of cathepsins B, H, and L and their inhibitors as markers of transitional cell carcinoma of the bladder
-
Staack A, Tolic D, Kristiansen G, Schnorr D, Loening SA, Jung K (2004) Expression of cathepsins B, H, and L and their inhibitors as markers of transitional cell carcinoma of the bladder. Urology 63:1089-1094
-
(2004)
Urology
, vol.63
, pp. 1089-1094
-
-
Staack, A.1
Tolic, D.2
Kristiansen, G.3
Schnorr, D.4
Loening, S.A.5
Jung, K.6
-
306
-
-
34748831073
-
Proteomic analysis of cathepsin B-And L-deficient mouse brain lysosomes
-
Stahl S, Reinders Y, Asan E, Mothes W, Conzelmann E, Sickmann A, Felbor U (2007) Proteomic analysis of cathepsin B-And L-deficient mouse brain lysosomes. Biochim Biophys Acta 1774:1237-1246
-
(2007)
Biochim Biophys Acta
, vol.1774
, pp. 1237-1246
-
-
Stahl, S.1
Reinders, Y.2
Asan, E.3
Mothes, W.4
Conzelmann, E.5
Sickmann, A.6
Felbor, U.7
-
307
-
-
0035174607
-
Molecular genetic profiling of gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasia
-
Stamey TA, Warrington JA, Caldwell MC, Chen ZX, Fan ZB, Mahadevappa M, McNeal JE, Nolley R, Zhang ZM (2001) Molecular genetic profiling of gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasia. J Urol 166:2171-2177
-
(2001)
J Urol
, vol.166
, pp. 2171-2177
-
-
Stamey, T.A.1
Warrington, J.A.2
Caldwell, M.C.3
Chen, Z.X.4
Fan, Z.B.5
Mahadevappa, M.6
McNeal, J.E.7
Nolley, R.8
Zhang, Z.M.9
-
308
-
-
10744220367
-
Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer
-
Stephan C, Yousef GM, Scorilas A, Jung K, Jung M, Kristiansen G, Hauptmann S, Kishi T, Nakamura T, Loening SA, Diamandis EP (2004) Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer. J Urol 171:187-191
-
(2004)
J Urol
, vol.171
, pp. 187-191
-
-
Stephan, C.1
Yousef, G.M.2
Scorilas, A.3
Jung, K.4
Jung, M.5
Kristiansen, G.6
Hauptmann, S.7
Kishi, T.8
Nakamura, T.9
Loening, S.A.10
Diamandis, E.P.11
-
309
-
-
0033597726
-
The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis
-
Sternlicht MD, Lochter A, Sympson CJ, Huey B, Rougier JP, Gray JW, Pinkel D, Bissell MJ, Werb Z (1999) The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell 98:137-146
-
(1999)
Cell
, vol.98
, pp. 137-146
-
-
Sternlicht, M.D.1
Lochter, A.2
Sympson, C.J.3
Huey, B.4
Rougier, J.P.5
Gray, J.W.6
Pinkel, D.7
Bissell, M.J.8
Werb, Z.9
-
310
-
-
79955458657
-
The calpain system and cancer
-
Storr SJ, Carragher NO, Frame MC, Parr T, Martin SG (2011) The calpain system and cancer. Nat Rev Cancer 11:364-374
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 364-374
-
-
Storr, S.J.1
Carragher, N.O.2
Frame, M.C.3
Parr, T.4
Martin, S.G.5
-
311
-
-
79958037582
-
Bone metastasis in prostate cancer: Emerging therapeutic strategies
-
Sturge J, Caley MP, Waxman J (2011) Bone metastasis in prostate cancer: emerging therapeutic strategies. Nat Rev Clin Oncol 8:357-368
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 357-368
-
-
Sturge, J.1
Caley, M.P.2
Waxman, J.3
-
312
-
-
66149088069
-
Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer
-
Sullivan S, Tosetto M, Kevans D, Coss A, Wang L, O'Donoghue D, Hyland J, Sheahan K, Mulcahy H, O'Sullivan J (2009) Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer. Int J Cancer 125:54-61
-
(2009)
Int J Cancer
, vol.125
, pp. 54-61
-
-
Sullivan, S.1
Tosetto, M.2
Kevans, D.3
Coss, A.4
Wang, L.5
O'donoghue, D.6
Hyland, J.7
Sheahan, K.8
Mulcahy, H.9
O'sullivan, J.10
-
313
-
-
77449150629
-
CYLD: A tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes
-
Sun SC (2010) CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes. Cell Death Differ 17:25-34
-
(2010)
Cell Death Differ
, vol.17
, pp. 25-34
-
-
Sun, S.C.1
-
314
-
-
0034902354
-
Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
-
Sunwoo JB, Chen Z, Dong G, Yeh N, Crowl Bancroft C, Sausville E, Adams J, Elliott P, Van Waes C (2001) Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 7:1419-1428
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1419-1428
-
-
Sunwoo, J.B.1
Chen, Z.2
Dong, G.3
Yeh, N.4
Crowl Bancroft, C.5
Sausville, E.6
Adams, J.7
Elliott, P.8
Van Waes, C.9
-
315
-
-
79955478095
-
C-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase
-
Szabo R, Rasmussen AL, Moyer AB, Kosa P, Schafer JM, Molinolo AA, Gutkind JS, Bugge TH (2011) c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase. Oncogene 30:2003-2016
-
(2011)
Oncogene
, vol.30
, pp. 2003-2016
-
-
Szabo, R.1
Rasmussen, A.L.2
Moyer, A.B.3
Kosa, P.4
Schafer, J.M.5
Molinolo, A.A.6
Gutkind, J.S.7
Bugge, T.H.8
-
316
-
-
44349156127
-
MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease
-
Szabova L, Chrysovergis K, Yamada SS, Holmbeck K (2008) MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease. Oncogene 27:3274-3281
-
(2008)
Oncogene
, vol.27
, pp. 3274-3281
-
-
Szabova, L.1
Chrysovergis, K.2
Yamada, S.S.3
Holmbeck, K.4
-
317
-
-
0037441314
-
Down-regulated expression of prostasin in high-grade or hormone-refractory human prostate cancers
-
Takahashi S, Suzuki S, Inaguma S, Ikeda Y, Cho YM, Hayashi N, Inoue T, Sugimura Y, Nishiyama N, Fujita T, Chao J, Ushijima T, Shirai T (2003) Down-regulated expression of prostasin in high-grade or hormone-refractory human prostate cancers. Prostate 54:187-193
-
(2003)
Prostate
, vol.54
, pp. 187-193
-
-
Takahashi, S.1
Suzuki, S.2
Inaguma, S.3
Ikeda, Y.4
Cho, Y.M.5
Hayashi, N.6
Inoue, T.7
Sugimura, Y.8
Nishiyama, N.9
Fujita, T.10
Chao, J.11
Ushijima, T.12
Shirai, T.13
-
318
-
-
0035909802
-
Characterization of hK4 (prostase), a prostate-specific serine protease: Activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-Type plasminogen activator and degradation of prostatic acid phosphatase
-
Takayama TK, McMullen BA, Nelson PS, Matsumura M, Fujikawa K (2001) Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-Type plasminogen activator and degradation of prostatic acid phosphatase. Biochemistry 40:15341-15348
-
(2001)
Biochemistry
, vol.40
, pp. 15341-15348
-
-
Takayama, T.K.1
McMullen, B.A.2
Nelson, P.S.3
Matsumura, M.4
Fujikawa, K.5
-
319
-
-
13444263249
-
Testisin, a glycosylphosphatidylinositol-linked serine protease, promotes malignant transformation in vitro and in vivo
-
Tang T, Kmet M, Corral L, Vartanian S, Tobler A, Papkoff J (2005) Testisin, a glycosylphosphatidylinositol-linked serine protease, promotes malignant transformation in vitro and in vivo. Cancer Res 65:868-878
-
(2005)
Cancer Res
, vol.65
, pp. 868-878
-
-
Tang, T.1
Kmet, M.2
Corral, L.3
Vartanian, S.4
Tobler, A.5
Papkoff, J.6
-
320
-
-
79955014374
-
Cross-domain inhibition of TACE ectodomain
-
Tape CJ, Willems SH, Dombernowsky SL, Stanley PL, Fogarasi M, Ouwehand W, McCafferty J, Murphy G (2011) Cross-domain inhibition of TACE ectodomain. Proc Natl Acad Sci U S A 108:5578-5583
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 5578-5583
-
-
Tape, C.J.1
Willems, S.H.2
Dombernowsky, S.L.3
Stanley, P.L.4
Fogarasi, M.5
Ouwehand, W.6
McCafferty, J.7
Murphy, G.8
-
321
-
-
77955957035
-
Nuclear cysteine cathepsin variants in thyroid carcinoma cells
-
Tedelind S, Poliakova K, Valeta A, Hunegnaw R, Yemanaberhan EL, Heldin NE, Kurebayashi J, Weber E, Kopitar-Jerala N, Turk B, Bogyo M, Brix K (2010) Nuclear cysteine cathepsin variants in thyroid carcinoma cells. Biol Chem 391:923-935
-
(2010)
Biol Chem
, vol.391
, pp. 923-935
-
-
Tedelind, S.1
Poliakova, K.2
Valeta, A.3
Hunegnaw, R.4
Yemanaberhan, E.L.5
Heldin, N.E.6
Kurebayashi, J.7
Weber, E.8
Kopitar-Jerala, N.9
Turk, B.10
Bogyo, M.11
Brix, K.12
-
322
-
-
70450190022
-
Proteasome inhibitors in cancer therapy
-
Testa U (2009) Proteasome inhibitors in cancer therapy. Curr Drug Targets 10:968-981
-
(2009)
Curr Drug Targets
, vol.10
, pp. 968-981
-
-
Testa, U.1
-
323
-
-
84855392626
-
An osteoblastderived proteinase controls cell survival via TGF-beta activation in the bone microenvironment
-
Thiolloy S, Edwards JR, Fingleton B, Rifkin DB, Matrisian LM, Lynch CC (2012) An osteoblastderived proteinase controls cell survival via TGF-beta activation in the bone microenvironment. PLoS One 7:e29862
-
(2012)
PLoS One
, vol.7
, pp. e29862
-
-
Thiolloy, S.1
Edwards, J.R.2
Fingleton, B.3
Rifkin, D.B.4
Matrisian, L.M.5
Lynch, C.C.6
-
324
-
-
69249094919
-
Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis
-
Thiolloy S, Halpern J, Holt GE, Schwartz HS, Mundy GR, Matrisian LM, Lynch CC (2009) Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis. Cancer Res 69:6747-6755
-
(2009)
Cancer Res
, vol.69
, pp. 6747-6755
-
-
Thiolloy, S.1
Halpern, J.2
Holt, G.E.3
Schwartz, H.S.4
Mundy, G.R.5
Matrisian, L.M.6
Lynch, C.C.7
-
325
-
-
77955401111
-
Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation
-
To S, Rodda SJ, Rathjen PD, Keough RA (2010) Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. PLoS One 5:e11702
-
(2010)
PLoS One
, vol.5
, pp. e11702
-
-
To, S.1
Rodda, S.J.2
Rathjen, P.D.3
Keough, R.A.4
-
326
-
-
44449160795
-
Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis
-
Tomita A, Kasaoka T, Inui T, Toyoshima M, Nishiyama H, Saiki H, Iguchi H, Nakajima M(2008) Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis. Clin Exp Metastasis 25:437-444
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 437-444
-
-
Tomita, A.1
Kasaoka, T.2
Inui, T.3
Toyoshima, M.4
Nishiyama, H.5
Saiki, H.6
Iguchi, H.7
Nakajima, M.8
-
327
-
-
84930582157
-
Recurrent fusion of TMPRSS2 and ETS transcription factors in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao XH, Tchinda J, Lee C, Shah RB, Rubin MA, Chinnaiyan AM (2006) Recurrent fusion of TMPRSS2 and ETS transcription factors in prostate cancer. FASEB J 20:A1327
-
(2006)
FASEB J
, vol.20
, pp. A1327
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.W.6
Varambally, S.7
Cao, X.H.8
Tchinda, J.9
Lee, C.10
Shah, R.B.11
Rubin, M.A.12
Chinnaiyan, A.M.13
-
328
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, Menon A, Jing X, Cao Q, Han B, Yu J, Wang L, Montie JE, Rubin MA, Pienta KJ, Roulston D, Shah RB, Varambally S, Mehra R, Chinnaiyan AM (2007) Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448:595-599
-
(2007)
Nature
, vol.448
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
Rubin, M.A.14
Pienta, K.J.15
Roulston, D.16
Shah, R.B.17
Varambally, S.18
Mehra, R.19
Chinnaiyan, A.M.20
more..
-
329
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, Cao Q, Prensner JR, Rubin MA, Shah RB, Mehra R, Chinnaiyan AM (2008) Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia (New York, NY) 10:177-188
-
(2008)
Neoplasia (New York, NY
, vol.10
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
Cao, X.4
Yu, J.5
Helgeson, B.E.6
Cao, Q.7
Prensner, J.R.8
Rubin, M.A.9
Shah, R.B.10
Mehra, R.11
Chinnaiyan, A.M.12
-
330
-
-
67649425225
-
ETS gene fusions in prostate cancer: From discovery to daily clinical practice
-
Tomlins SA, Bjartell A, Chinnaiyan AM, Jenster G, Nam RK, Rubin MA, Schalken JA (2009) ETS gene fusions in prostate cancer: from discovery to daily clinical practice. Eur Urol 56:275-286
-
(2009)
Eur Urol
, vol.56
, pp. 275-286
-
-
Tomlins, S.A.1
Bjartell, A.2
Chinnaiyan, A.M.3
Jenster, G.4
Nam, R.K.5
Rubin, M.A.6
Schalken, J.A.7
-
331
-
-
57649155897
-
Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression
-
Tripathi M, Nandana S, Yamashita H, Ganesan R, Kirchhofer D, Quaranta V (2008) Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression. J Biol Chem 283:30576-30584
-
(2008)
J Biol Chem
, vol.283
, pp. 30576-30584
-
-
Tripathi, M.1
Nandana, S.2
Yamashita, H.3
Ganesan, R.4
Kirchhofer, D.5
Quaranta, V.6
-
332
-
-
0025951220
-
Hepsin, a cell membrane-Associated protease-characterization, tissue distribution, and gene localization
-
Tsuji A, Torresrosado A, Arai T, Lebeau MM, Lemons RS, Chou SH, Kurachi K (1991) Hepsin, a cell membrane-Associated protease-characterization, tissue distribution, and gene localization. J Biol Chem 266:16948-16953
-
(1991)
J Biol Chem
, vol.266
, pp. 16948-16953
-
-
Tsuji, A.1
Torresrosado, A.2
Arai, T.3
Lebeau, M.M.4
Lemons, R.S.5
Chou, S.H.6
Kurachi, K.7
-
333
-
-
0037648896
-
Molecular targeting therapy of cancer: Drug resistance, apoptosis and survival signal
-
Tsuruo T, Naito M, Tomida A, Fujita N, Mashima T, Sakamoto H, Haga N (2003) Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal. Cancer Sci 94:15-21
-
(2003)
Cancer Sci
, vol.94
, pp. 15-21
-
-
Tsuruo, T.1
Naito, M.2
Tomida, A.3
Fujita, N.4
Mashima, T.5
Sakamoto, H.6
Haga, N.7
-
334
-
-
38449089504
-
RNAimediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis
-
Tummalapalli P, Spomar D, Gondi CS, Olivero WC, Gujrati M, Dinh DH, Rao JS (2007) RNAimediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis. Int J Oncol 31:1039-1050
-
(2007)
Int J Oncol
, vol.31
, pp. 1039-1050
-
-
Tummalapalli, P.1
Spomar, D.2
Gondi, C.S.3
Olivero, W.C.4
Gujrati, M.5
Dinh, D.H.6
Rao, J.S.7
-
335
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
Turk V, Stoka V, Vasiljeva O, Renko M, Sun T, Turk B, Turk D (2012) Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim Biophys Acta 1824:68-88
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
Sun, T.5
Turk, B.6
Turk, D.7
-
337
-
-
0030879756
-
An epithelial serine protease activates the amiloride-sensitive sodium channel
-
Vallet V, Chraibi A, Gaeggeler HP, Horisberger JD, Rossier BC (1997) An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature 389:607-610
-
(1997)
Nature
, vol.389
, pp. 607-610
-
-
Vallet, V.1
Chraibi, A.2
Gaeggeler, H.P.3
Horisberger, J.D.4
Rossier, B.C.5
-
338
-
-
71449113533
-
Metalloprotease ADAM10 is required for Notch1 site 2 cleavage
-
van Tetering G, van Diest P, Verlaan I, van der Wall E, Kopan R, VooijsM(2009) Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. J Biol Chem 284:31018-31027
-
(2009)
J Biol Chem
, vol.284
, pp. 31018-31027
-
-
Van Tetering, G.1
Van Diest, P.2
Verlaan, I.3
Van Der Wall, E.4
Kopan, R.5
Vooijs, M.6
-
339
-
-
38649084746
-
Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion
-
Vasiljeva O, Turk B (2008) Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion. Biochimie 90:380-386
-
(2008)
Biochimie
, vol.90
, pp. 380-386
-
-
Vasiljeva, O.1
Turk, B.2
-
340
-
-
33744917827
-
Tumor cell-derived and macrophagederived cathepsin B promotes progression and lung metastasis of mammary cancer
-
Vasiljeva O, Papazoglou A, Kruger A, Brodoefel H, Korovin M, Deussing J, Augustin N, Nielsen BS, Almholt K, Bogyo M, Peters C, Reinheckel T (2006) Tumor cell-derived and macrophagederived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res 66:5242-5250
-
(2006)
Cancer Res
, vol.66
, pp. 5242-5250
-
-
Vasiljeva, O.1
Papazoglou, A.2
Kruger, A.3
Brodoefel, H.4
Korovin, M.5
Deussing, J.6
Augustin, N.7
Nielsen, B.S.8
Almholt, K.9
Bogyo, M.10
Peters, C.11
Reinheckel, T.12
-
341
-
-
47049095033
-
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
-
Vasiljeva O, Korovin M, Gajda M, Brodoefel H, Bojic L, Kruger A, Schurigt U, Sevenich L, Turk B, Peters C, Reinheckel T (2008) Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice. Oncogene 27:4191-4199
-
(2008)
Oncogene
, vol.27
, pp. 4191-4199
-
-
Vasiljeva, O.1
Korovin, M.2
Gajda, M.3
Brodoefel, H.4
Bojic, L.5
Kruger, A.6
Schurigt, U.7
Sevenich, L.8
Turk, B.9
Peters, C.10
Reinheckel, T.11
-
342
-
-
25444511458
-
Overexpression of cathepsin F, matrix metalloproteinases 11 and 12 in cervical cancer
-
Vazquez-Ortiz G, Pina-Sanchez P, Vazquez K, Duenas A, Taja L, Mendoza P, Garcia JA, Salcedo M (2005) Overexpression of cathepsin F, matrix metalloproteinases 11 and 12 in cervical cancer. BMC Cancer 5:68
-
(2005)
BMC Cancer
, vol.5
, pp. 68
-
-
Vazquez-Ortiz, G.1
Pina-Sanchez, P.2
Vazquez, K.3
Duenas, A.4
Taja, L.5
Mendoza, P.6
Garcia, J.A.7
Salcedo, M.8
-
343
-
-
77955374803
-
MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice
-
Veeravalli KK, Chetty C, Ponnala S, Gondi CS, Lakka SS, Fassett D, Klopfenstein JD, Dinh DH, Gujrati M, Rao JS (2010) MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice. PLoS One 5:e11583
-
(2010)
PLoS One
, vol.5
, pp. e11583
-
-
Veeravalli, K.K.1
Chetty, C.2
Ponnala, S.3
Gondi, C.S.4
Lakka, S.S.5
Fassett, D.6
Klopfenstein, J.D.7
Dinh, D.H.8
Gujrati, M.9
Rao, J.S.10
-
345
-
-
33746604484
-
The ratio of Matriptase/HAI-l mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
-
Vogel LK, Saebo M, Skjelbred CF, Abell K, Pedersen EDK, Vogel U, Kure EH (2006) The ratio of Matriptase/HAI-l mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals. BMC Cancer 6:176
-
(2006)
BMC Cancer
, vol.6
, pp. 176
-
-
Vogel, L.K.1
Saebo, M.2
Skjelbred, C.F.3
Abell, K.4
Pedersen, E.D.K.5
Vogel, U.6
Kure, E.H.7
-
346
-
-
56449106087
-
The ubiquitin-proteasome system in colorectal cancer
-
Voutsadakis IA (2008) The ubiquitin-proteasome system in colorectal cancer. Biochim Biophys Acta 1782:800-808
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 800-808
-
-
Voutsadakis, I.A.1
-
347
-
-
33749442906
-
Molecular imaging of matrix metalloproteinases in vivo using small molecule inhibitors for SPECT and PET
-
Wagner S, Breyholz HJ, Faust A, Holtke C, Levkau B, Schober O, Schafers M, Kopka K (2006) Molecular imaging of matrix metalloproteinases in vivo using small molecule inhibitors for SPECT and PET. Curr Med Chem 13:2819-2838
-
(2006)
Curr Med Chem
, vol.13
, pp. 2819-2838
-
-
Wagner, S.1
Breyholz, H.J.2
Faust, A.3
Holtke, C.4
Levkau, B.5
Schober, O.6
Schafers, M.7
Kopka, K.8
-
348
-
-
79955027296
-
The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis
-
Wagstaff L, Kelwick R, Decock J, Edwards DR (2011) The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis. Front Biosci 16:1861-1872
-
(2011)
Front Biosci
, vol.16
, pp. 1861-1872
-
-
Wagstaff, L.1
Kelwick, R.2
Decock, J.3
Edwards, D.R.4
-
349
-
-
0343012075
-
A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer
-
Wallrapp C, Hahnel S, Muller-Pillasch F, Burghardt B, Iwamura T, Ruthenburger M, Lerch MM, Adler G, Gress TM (2000) A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer. Cancer Res 60:2602-2606
-
(2000)
Cancer Res
, vol.60
, pp. 2602-2606
-
-
Wallrapp, C.1
Hahnel, S.2
Muller-Pillasch, F.3
Burghardt, B.4
Iwamura, T.5
Ruthenburger, M.6
Lerch, M.M.7
Adler, G.8
Gress, T.M.9
-
350
-
-
0033610817
-
Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization
-
Wang B, Shi GP, Yao PM, Li Z, Chapman HA, Bromme D (1998) Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization. J Biol Chem 273:32000-32008
-
(1998)
J Biol Chem
, vol.273
, pp. 32000-32008
-
-
Wang, B.1
Shi, G.P.2
Yao, P.M.3
Li, Z.4
Chapman, H.A.5
Bromme, D.6
-
351
-
-
33646827205
-
Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors
-
Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP (2006) Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem 281:6020-6029
-
(2006)
J Biol Chem
, vol.281
, pp. 6020-6029
-
-
Wang, B.1
Sun, J.2
Kitamoto, S.3
Yang, M.4
Grubb, A.5
Chapman, H.A.6
Kalluri, R.7
Shi, G.P.8
-
352
-
-
77958603409
-
Antibody targeting of cathepsin S inhibits angiogenesis and synergistically enhances anti-VEGF
-
Ward C, Kuehn D, Burden RE, Gormley JA, Jaquin TJ, Gazdoiu M, Small D, Bicknell R, Johnston JA, Scott CJ, Olwill SA (2010) Antibody targeting of cathepsin S inhibits angiogenesis and synergistically enhances anti-VEGF. PLoS One 5:e12543
-
(2010)
PLoS One
, vol.5
, pp. e12543
-
-
Ward, C.1
Kuehn, D.2
Burden, R.E.3
Gormley, J.A.4
Jaquin, T.J.5
Gazdoiu, M.6
Small, D.7
Bicknell, R.8
Johnston, J.A.9
Scott, C.J.10
Olwill, S.A.11
-
353
-
-
33748979745
-
Invadopodia: Specialized cell structures for cancer invasion
-
Weaver AM (2006) Invadopodia: specialized cell structures for cancer invasion. Clin Exp Metastasis 23:97-105
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 97-105
-
-
Weaver, A.M.1
-
354
-
-
79955022479
-
Type II Transmembrane Serine Protease (TTSP) deregulation in cancer
-
Webb SL, Sanders AJ, Mason MD, Jiang WG (2011) Type II Transmembrane Serine Protease (TTSP) deregulation in cancer. Front Biosci 16:539-552
-
(2011)
Front Biosci
, vol.16
, pp. 539-552
-
-
Webb, S.L.1
Sanders, A.J.2
Mason, M.D.3
Jiang, W.G.4
-
355
-
-
0032951071
-
In vivo imaging of tumors with protease-Activated near-infrared fluorescent probes
-
Weissleder R, Tung CH, Mahmood U, Bogdanov A Jr (1999) In vivo imaging of tumors with protease-Activated near-infrared fluorescent probes. Nat Biotechnol 17:375-378
-
(1999)
Nat Biotechnol
, vol.17
, pp. 375-378
-
-
Weissleder, R.1
Tung, C.H.2
Mahmood, U.3
Bogdanov, A.4
-
357
-
-
80053049819
-
Inhibitors of cathepsin K: A patent review 2004-2010)
-
Wijkmans J, Gossen J (2011) Inhibitors of cathepsin K: a patent review (2004-2010). Expert Opin Ther Pat 21:1611-1629
-
(2011)
Expert Opin Ther Pat
, vol.21
, pp. 1611-1629
-
-
Wijkmans, J.1
Gossen, J.2
-
358
-
-
77951833365
-
Prostate-specific antigen (PSA) is activated by KLK2 in prostate cancer ex vivo models and in prostate-Targeted PSA/KLK2 double transgenic mice
-
Williams SA, Xu Y, De Marzo AM, Isaacs JT, Denmeade SR (2010) Prostate-specific antigen (PSA) is activated by KLK2 in prostate cancer ex vivo models and in prostate-Targeted PSA/KLK2 double transgenic mice. Prostate 70:788-796
-
(2010)
Prostate
, vol.70
, pp. 788-796
-
-
Williams, S.A.1
Xu, Y.2
De Marzo, A.M.3
Isaacs, J.T.4
Denmeade, S.R.5
-
359
-
-
0031036359
-
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin
-
Wilson CL, Heppner KJ, Labosky PA, Hogan BL, Matrisian LM (1997) Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc Natl Acad Sci U S A 94:1402-1407
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1402-1407
-
-
Wilson, C.L.1
Heppner, K.J.2
Labosky, P.A.3
Hogan, B.L.4
Matrisian, L.M.5
-
361
-
-
84863229642
-
Cathepsin B inhibition limits bone metastasis in breast cancer
-
Withana NP, Blum G, Sameni M, Slaney C, Anbalagan A, Olive MB, Bidwell BN, Edgington L, Wang L, Moin K, Sloane BF, Anderson RL, Bogyo MS, Parker BS (2012) Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res 72:1199-1209
-
(2012)
Cancer Res
, vol.72
, pp. 1199-1209
-
-
Withana, N.P.1
Blum, G.2
Sameni, M.3
Slaney, C.4
Anbalagan, A.5
Olive, M.B.6
Bidwell, B.N.7
Edgington, L.8
Wang, L.9
Moin, K.10
Sloane, B.F.11
Anderson, R.L.12
Bogyo, M.S.13
Parker, B.S.14
-
362
-
-
52049111595
-
Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor
-
Witters L, Scherle P, Friedman S, Fridman J, Caulder E, Newton R, Lipton A (2008) Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor. Cancer Res 68:7083-7089
-
(2008)
Cancer Res
, vol.68
, pp. 7083-7089
-
-
Witters, L.1
Scherle, P.2
Friedman, S.3
Fridman, J.4
Caulder, E.5
Newton, R.6
Lipton, A.7
-
363
-
-
0028916958
-
Decreased tumor formation in 7, 12-dimethylbenzanthracene-Treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis
-
Witty JP, Lempka T, Coffey RJ Jr, Matrisian LM (1995) Decreased tumor formation in 7, 12-dimethylbenzanthracene-Treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer Res 55:1401-1406
-
(1995)
Cancer Res
, vol.55
, pp. 1401-1406
-
-
Witty, J.P.1
Lempka, T.2
Coffey, R.J.3
Matrisian, L.M.4
-
364
-
-
34547655938
-
Hepsin and prostate cancer
-
Wu QY, Parry G (2007) Hepsin and prostate cancer. Front Biosci 12:5052-5059
-
(2007)
Front Biosci
, vol.12
, pp. 5052-5059
-
-
Wu, Q.Y.1
Parry, G.2
-
365
-
-
77953229918
-
Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy
-
Wu SK, Sakamoto KM, Milani M, Aldana-Masankgay G, Fan D, Wu K, Lee CW, Cho CH, Yu J, Sung JJ (2010) Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy. Drug Resist Updat 13:87-92
-
(2010)
Drug Resist Updat
, vol.13
, pp. 87-92
-
-
Wu, S.K.1
Sakamoto, K.M.2
Milani, M.3
Aldana-Masankgay, G.4
Fan, D.5
Wu, K.6
Lee, C.W.7
Cho, C.H.8
Yu, J.9
Sung, J.J.10
-
366
-
-
79955473609
-
Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells
-
Wu SM, Huang YH, Yeh CT, Tsai MM, Liao CH, Cheng WL, Chen WJ, Lin KH (2011) Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells. Oncogene 30:2057-2069
-
(2011)
Oncogene
, vol.30
, pp. 2057-2069
-
-
Wu, S.M.1
Huang, Y.H.2
Yeh, C.T.3
Tsai, M.M.4
Liao, C.H.5
Cheng, W.L.6
Chen, W.J.7
Lin, K.H.8
-
367
-
-
0034712832
-
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway
-
Xu J, Attisano L (2000) Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A 97:4820-4825
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4820-4825
-
-
Xu, J.1
Attisano, L.2
-
368
-
-
69249215318
-
Cathepsin S is aberrantly overexpressed in human hepatocellular carcinoma
-
Xu J, Li D, Ke Z, Liu R, Maubach G, Zhuo L (2009) Cathepsin S is aberrantly overexpressed in human hepatocellular carcinoma. Mol Med Report 2:713-718
-
(2009)
Mol Med Report
, vol.2
, pp. 713-718
-
-
Xu, J.1
Li, D.2
Ke, Z.3
Liu, R.4
Maubach, G.5
Zhuo, L.6
-
369
-
-
33645748575
-
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture
-
Xuan JA, Schneider D, Toy P, Lin R, Newton A, Zhu Y, Finster S, Vogel D, Mintzer B, Dinter H, Light D, Parry R, Polokoff M, Whitlow M, Wu QY, Parry G (2006) Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. Cancer Res 66:3611-3619
-
(2006)
Cancer Res
, vol.66
, pp. 3611-3619
-
-
Xuan, J.A.1
Schneider, D.2
Toy, P.3
Lin, R.4
Newton, A.5
Zhu, Y.6
Finster, S.7
Vogel, D.8
Mintzer, B.9
Dinter, H.10
Light, D.11
Parry, R.12
Polokoff, M.13
Whitlow, M.14
Wu, Q.Y.15
Parry, G.16
-
370
-
-
0038486779
-
Molecular regulation of human cathepsin B: Implication in pathologies
-
Yan S, Sloane BF (2003) Molecular regulation of human cathepsin B: implication in pathologies. Biol Chem 384:845-854
-
(2003)
Biol Chem
, vol.384
, pp. 845-854
-
-
Yan, S.1
Sloane, B.F.2
-
371
-
-
79751480144
-
Stromal expression of cathepsin K in squamous cell carcinoma
-
Yan X, Takahara M, Xie L, Oda Y, Nakahara T, Uchi H, Takeuchi S, Tu Y, Moroi Y, Furue M (2011) Stromal expression of cathepsin K in squamous cell carcinoma. J Eur Acad Dermatol Venereol 25:362-365
-
(2011)
J Eur Acad Dermatol Venereol
, vol.25
, pp. 362-365
-
-
Yan, X.1
Takahara, M.2
Xie, L.3
Oda, Y.4
Nakahara, T.5
Uchi, H.6
Takeuchi, S.7
Tu, Y.8
Moroi, Y.9
Furue, M.10
-
372
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
-
Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, Matrisian LM, Carbone DP, Lin PC (2004) Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 6:409-421
-
(2004)
Cancer Cell
, vol.6
, pp. 409-421
-
-
Yang, L.1
Debusk, L.M.2
Fukuda, K.3
Fingleton, B.4
Green-Jarvis, B.5
Shyr, Y.6
Matrisian, L.M.7
Carbone, D.P.8
Lin, P.C.9
-
373
-
-
77956320690
-
Cathepsin S mediates gastric cancer cell migration and invasion via a putative network of metastasis-Associated proteins
-
Yang Y, Lim SK, Choong LY, Lee H, Chen Y, Chong PK, Ashktorab H, Wang TT, Salto-Tellez M, Yeoh KG, Lim YP (2010) Cathepsin S mediates gastric cancer cell migration and invasion via a putative network of metastasis-Associated proteins. J Proteome Res 9:4767-4778
-
(2010)
J Proteome Res
, vol.9
, pp. 4767-4778
-
-
Yang, Y.1
Lim, S.K.2
Choong, L.Y.3
Lee, H.4
Chen, Y.5
Chong, P.K.6
Ashktorab, H.7
Wang, T.T.8
Salto-Tellez, M.9
Yeoh, K.G.10
Lim, Y.P.11
-
374
-
-
0028282969
-
Prostasin is a novel human serine proteinase from seminal fluid-purification, tissue distribution, and localization in prostate-gland
-
Yu JX, Chao L, Chao J (1994) Prostasin is a novel human serine proteinase from seminal fluid-purification, tissue distribution, and localization in prostate-gland. J Biol Chem 269:18843-18848
-
(1994)
J Biol Chem
, vol.269
, pp. 18843-18848
-
-
Yu, J.X.1
Chao, L.2
Chao, J.3
-
375
-
-
33644858343
-
The unfolded protein response: A stress signaling pathway critical for health and disease
-
Zhang K, Kaufman RJ (2006) The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 66:S102-S109
-
(2006)
Neurology
, vol.66
, pp. S102-S109
-
-
Zhang, K.1
Kaufman, R.J.2
-
376
-
-
76749124316
-
VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
-
Zhang Z, Neiva KG, Lingen MW, Ellis LM, Nor JE (2010) VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2. Cell Death Differ 17:499-512
-
(2010)
Cell Death Differ
, vol.17
, pp. 499-512
-
-
Zhang, Z.1
Neiva, K.G.2
Lingen, M.W.3
Ellis, L.M.4
Nor, J.E.5
-
377
-
-
58349113405
-
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: A putative mechanism
-
Zheng X, Chu F, Chou PM, Gallati C, Dier U, Mirkin BL, Mousa SA, Rebbaa A (2009) Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol 296:C65-C74
-
(2009)
Am J Physiol Cell Physiol
, vol.296
, pp. C65-C74
-
-
Zheng, X.1
Chu, F.2
Chou, P.M.3
Gallati, C.4
Dier, U.5
Mirkin, B.L.6
Mousa, S.A.7
Rebbaa, A.8
-
378
-
-
0034282829
-
Urokinase-Type plasminogen activator and its receptor synergize to promote pathogenic proteolysis
-
Zhou HM, Nichols A, Meda P, Vassalli JD (2000) Urokinase-Type plasminogen activator and its receptor synergize to promote pathogenic proteolysis. EMBO J 19:4817-4826
-
(2000)
EMBO J
, vol.19
, pp. 4817-4826
-
-
Zhou, H.M.1
Nichols, A.2
Meda, P.3
Vassalli, J.D.4
-
379
-
-
33745791118
-
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer
-
Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA (2006) Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell 10:39-50
-
(2006)
Cancer Cell
, vol.10
, pp. 39-50
-
-
Zhou, B.B.1
Peyton, M.2
He, B.3
Liu, C.4
Girard, L.5
Caudler, E.6
Lo, Y.7
Baribaud, F.8
Mikami, I.9
Reguart, N.10
Yang, G.11
Li, Y.12
Yao, W.13
Vaddi, K.14
Gazdar, A.F.15
Friedman, S.M.16
Jablons, D.M.17
Newton, R.C.18
Fridman, J.S.19
Minna, J.D.20
Scherle, P.A.21
more..
-
380
-
-
79953198272
-
The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts
-
Zigrino P, Nischt R, Mauch C (2011) The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts. J Biol Chem 286:6801-6807
-
(2011)
J Biol Chem
, vol.286
, pp. 6801-6807
-
-
Zigrino, P.1
Nischt, R.2
Mauch, C.3
-
381
-
-
0034722898
-
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment
-
Zucker S, Cao J, Chen WT (2000) Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment. Oncogene 19:6642-6650.
-
(2000)
Oncogene
, vol.19
, pp. 6642-6650
-
-
Zucker, S.1
Cao, J.2
Chen, W.T.3
|