Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

Journal of Experimental Medicine

Volumn 191, Issue 7, 2000, Pages 1177-1185

  Shi, Guo Ping ^a   Bryant, Rebecca A R ^b   Riese, Richard ^a   Verhelst, Steven ^b   Driessen, Christoph ^b   Li, Zhenqiang ^c   Bromme, Dieter ^c   Ploegh, Hidde L ^b   Chapman, Harold A ^a,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antigen presentation; Antigen presenting cell; Cysteine protease; Protease inhibitor; Proteolysis

Indexed keywords

CATHEPSIN; CATHEPSIN F; CATHEPSIN S; CATHEPSIN Z; CELL MEMBRANE PROTEIN; CLASS II ASSOCIATED INVARIANT CHAIN PEPTIDE; CYSTEINE PROTEINASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; ENZYME SPECIFICITY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SPLEEN CELL;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; CATHEPSINS; CRICETINAE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; ENDOPEPTIDASES; GENE EXPRESSION; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOGLOBULIN E; LEUCINE; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDES; SULFONES;

EID: 0034599498     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.7.1177     Document Type: Article

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