-
1
-
-
0037803570
-
Human and mouse proteases: A comparative genomic approach
-
DOI 10.1038/nrg1111
-
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C. Human and mouse proteases: a comparative genomic approach. Nat Rev Genet. 2003;4(7):544-558. (Pubitemid 36781345)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.7
, pp. 544-558
-
-
Puente, X.S.1
Sanchez, L.M.2
Overall, C.M.3
Lopez-Otin, C.4
-
2
-
-
35848944306
-
'Species' of peptidases
-
Barrett AJ, Rawlings ND. 'Species' of peptidases. Biol Chem. 2007;388(11):1151-1157.
-
(2007)
Biol Chem
, vol.388
, Issue.11
, pp. 1151-1157
-
-
Barrett, A.J.1
Rawlings, N.D.2
-
3
-
-
0013574428
-
Über die Proteasen der Magenschleimhaut. Erste Abhandlung über die Enzyme der Leukozyten
-
Willstätter R, Bamann E. Über die Proteasen der Magenschleimhaut. Erste Abhandlung über die Enzyme der Leukozyten. Hoppe-Seyler's Z Physiol Chem. 1929;180(1-3):127-143.
-
(1929)
Hoppe-Seyler's Z Physiol Chem
, vol.180
, Issue.1-3
, pp. 127-143
-
-
Willstätter, R.1
Bamann, E.2
-
4
-
-
38549096018
-
MEROPS: The peptidase database
-
Rawlings ND, Morton FR, Kok CY, Kong J, Barrett AJ. MEROPS: the peptidase database. Nucleic Acids Res. 2008;36(Database issue):D320-D325.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.DATABASE ISSUE
-
-
Rawlings, N.D.1
Morton, F.R.2
Kok, C.Y.3
Kong, J.4
Barrett, A.J.5
-
5
-
-
75149137394
-
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice
-
Wartmann T, et al. Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice. Gastroenterology. 2010;138(2):726-737.
-
(2010)
Gastroenterology
, vol.138
, Issue.2
, pp. 726-737
-
-
Wartmann, T.1
-
6
-
-
40649110538
-
Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms
-
Puri N, Roche PA. Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms. Proc Natl Acad Sci U S A. 2008;105(7):2580-2585.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.7
, pp. 2580-2585
-
-
Puri, N.1
Roche, P.A.2
-
7
-
-
34547654202
-
Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease
-
Sever S, et al. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. J Clin Invest. 2007;117(8):2095-2104.
-
(2007)
J Clin Invest
, vol.117
, Issue.8
, pp. 2095-2104
-
-
Sever, S.1
-
8
-
-
51349162919
-
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
-
Faul C, et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med. 2008;14(9):931-938.
-
(2008)
Nat Med
, vol.14
, Issue.9
, pp. 931-938
-
-
Faul, C.1
-
9
-
-
4544377833
-
3 integrin
-
DOI 10.1074/jbc.M401973200
-
Reiser J, et al. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem. 2004;279(33):34827-34832. (Pubitemid 39318116)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34827-34832
-
-
Reiser, J.1
Oh, J.2
Shirato, I.3
Asanuma, K.4
Hug, A.5
Mundel, T.M.6
Honey, K.7
Ishidoh, K.8
Kominami, E.9
Kreidberg, J.A.10
Tomino, Y.11
Mundel, P.12
-
10
-
-
1942470581
-
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
-
Goulet B, et al. A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Mol Cell. 2004;14(2):207-219.
-
(2004)
Mol Cell
, vol.14
, Issue.2
, pp. 207-219
-
-
Goulet, B.1
-
11
-
-
57349110664
-
Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1
-
Alcalay NI, et al. Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1. Am J Physiol Renal Physiol. 2008;295(6):F1725-F1734.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
, Issue.6
-
-
Alcalay, N.I.1
-
12
-
-
33846164404
-
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
-
DOI 10.2174/138161207780162962
-
Vasiljeva O, Reinheckel T, Peters C, Turk D, Turk V, Turk B. Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr Pharm Des. 2007;13(4):387-403. (Pubitemid 46477760)
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.4
, pp. 387-403
-
-
Vasiljeva, O.1
Reinheckel, T.2
Peters, C.3
Turk, D.4
Turk, V.5
Turk, B.6
-
13
-
-
0037805704
-
Lysosomal cysteine proteases regulate antigen presentation
-
DOI 10.1038/nri1110
-
Honey K, Rudensky AY. Lysosomal cysteine proteases regulate antigen presentation. Nat Rev Immunol. 2003;3(6):472-482. (Pubitemid 37339187)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.6
, pp. 472-482
-
-
Honey, K.1
Rudensky, A.Y.2
-
14
-
-
37549068912
-
Cathepsin K inhibitors: A novel target for osteoporosis therapy
-
Stoch SA, Wagner JA. Cathepsin K inhibitors: a novel target for osteoporosis therapy. Clin Pharmacol Ther. 2008;83(1):172-176.
-
(2008)
Clin Pharmacol Ther
, vol.83
, Issue.1
, pp. 172-176
-
-
Stoch, S.A.1
Wagner, J.A.2
-
15
-
-
58049204438
-
Potential new drug targets for osteoporosis
-
Deal C. Potential new drug targets for osteoporosis. Nat Clin Pract Rheumatol. 2009;5(1):20-27.
-
(2009)
Nat Clin Pract Rheumatol
, vol.5
, Issue.1
, pp. 20-27
-
-
Deal, C.1
-
16
-
-
0038481173
-
Thyroid functions of mouse cathepsins B, K, and L
-
Friedrichs B, et al. Thyroid functions of mouse cathepsins B, K, and L. J Clin Invest. 2003;111(11):1733-1745.
-
(2003)
J Clin Invest
, vol.111
, Issue.11
, pp. 1733-1745
-
-
Friedrichs, B.1
-
17
-
-
58149101263
-
Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression
-
Funkelstein L, et al. Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression. J Biol Chem. 2008;283(51):35652-35659.
-
(2008)
J Biol Chem
, vol.283
, Issue.51
, pp. 35652-35659
-
-
Funkelstein, L.1
-
18
-
-
38649111363
-
Cysteine cathepsins: Cellular roadmap to different functions
-
DOI 10.1016/j.biochi.2007.07.024, PII S0300908407002003
-
Brix K, Dunkhorst A, Mayer K, Jordans S. Cysteine cathepsins: cellular roadmap to different functions. Biochimie. 2008;90(2):194-207. (Pubitemid 351172569)
-
(2008)
Biochimie
, vol.90
, Issue.2
, pp. 194-207
-
-
Brix, K.1
Dunkhorst, A.2
Mayer, K.3
Jordans, S.4
-
19
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
Mohamed MM, Sloane BF. Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer. 2006;6(10):764-775.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.10
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
20
-
-
35248897299
-
Cathepsin cysteine proteases in cardiovascular disease
-
DOI 10.1096/fj.06-7924com
-
Lutgens SP, Cleutjens KB, Daemen MJ, Heeneman S. Cathepsin cysteine proteases in cardiovascular disease. FASEB J. 2007;21(12):3029-3041. (Pubitemid 47565524)
-
(2007)
FASEB Journal
, vol.21
, Issue.12
, pp. 3029-3041
-
-
Lutgens, S.P.M.1
Cleutjens, K.B.J.M.2
Daemen, M.J.A.P.3
Heeneman, S.4
-
21
-
-
0035193513
-
Splice variants of human cathepsin L mRNA show different expression rates
-
Abudula A, Rommerskirch W, Weber E, Gunther D, Wiederanders B. Splice variants of human cathepsin L mRNA show different expression rates. Biol Chem. 2001;382(11):1583-1591.
-
(2001)
Biol Chem
, vol.382
, Issue.11
, pp. 1583-1591
-
-
Abudula, A.1
Rommerskirch, W.2
Weber, E.3
Gunther, D.4
Wiederanders, B.5
-
22
-
-
0036183134
-
Characterization of human cathepsin L promoter and identification of binding sites for NF-Y, Sp1 and Sp3 that are essential for its activity
-
DOI 10.1042/0264-6021:3610173
-
Jean D, Guillaume N, Frade R. Characterization of human cathepsin L promoter and identification of binding sites for NF-Y, Sp1 and Sp3 that are essential for its activity. Biochem J. 2002;361(pt 1):173-184. (Pubitemid 34171421)
-
(2002)
Biochemical Journal
, vol.361
, Issue.1
, pp. 173-184
-
-
Jean, D.1
Guillaume, N.2
Frade, R.3
-
23
-
-
46249129706
-
Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: Role of its 5′-untranslated region
-
DOI 10.1042/BJ20071255
-
Jean D, Rousselet N, Frade R. Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: role of its 5′-untranslated region. Biochem J. 2008;413(1):125-134. (Pubitemid 351946868)
-
(2008)
Biochemical Journal
, vol.413
, Issue.1
, pp. 125-134
-
-
Jean, D.1
Rousselet, N.2
Frade, R.3
-
24
-
-
33646886645
-
Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin
-
Bulynko YA, Hsing LC, Mason RW, Tremethick DJ, Grigoryev SA. Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin. Mol Cell Biol. 2006;26(11):4172-4184.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.11
, pp. 4172-4184
-
-
Bulynko, Y.A.1
Hsing, L.C.2
Mason, R.W.3
Tremethick, D.J.4
Grigoryev, S.A.5
-
25
-
-
53549094681
-
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation
-
Duncan EM, et al. Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell. 2008;135(2):284-294.
-
(2008)
Cell
, vol.135
, Issue.2
, pp. 284-294
-
-
Duncan, E.M.1
-
27
-
-
0030038759
-
Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases
-
DOI 10.1021/bi952736s
-
Carmona E, et al. Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases. Biochemistry. 1996;35(25):8149-8157. (Pubitemid 26234914)
-
(1996)
Biochemistry
, vol.35
, Issue.25
, pp. 8149-8157
-
-
Carmona, E.1
Dufour, E.2
Plouffe, C.3
Takebe, S.4
Mason, P.5
Mort, J.S.6
Menard, R.7
-
28
-
-
59949084805
-
Selectivity of propeptide-enzyme interaction in cathepsin L-like cysteine proteases
-
Schilling K, et al. Selectivity of propeptide-enzyme interaction in cathepsin L-like cysteine proteases. Biol Chem. 2009;390(2):167-174.
-
(2009)
Biol Chem
, vol.390
, Issue.2
, pp. 167-174
-
-
Schilling, K.1
-
29
-
-
0029902382
-
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment
-
Coulombe R, Grochulski P, Sivaraman J, Menard R, Mort JS, Cygler M. Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. EMBO J. 1996;15(20):5492-5503. (Pubitemid 26385609)
-
(1996)
EMBO Journal
, vol.15
, Issue.20
, pp. 5492-5503
-
-
Coulombe, R.1
Grochulski, P.2
Sivaraman, J.3
Menard, R.4
Mort, J.S.5
Cygler, M.6
-
30
-
-
0035801514
-
Lysosomal cysteine proteases: Facts and opportunities
-
DOI 10.1093/emboj/20.17.4629
-
Turk V, Turk B, Turk D. Lysosomal cysteine proteases: facts and opportunities. EMBO J. 2001;20(17):4629-4633. (Pubitemid 32848615)
-
(2001)
EMBO Journal
, vol.20
, Issue.17
, pp. 4629-4633
-
-
Turk, V.1
Turk, B.2
Turk, D.3
-
31
-
-
0040909177
-
The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide
-
Quraishi O, et al. The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide. Biochemistry. 1999;38(16):5017-5023. (Pubitemid 129514772)
-
(1999)
Biochemistry
, vol.38
, Issue.16
, pp. 5017-5023
-
-
Quraishi, O.1
Nagler, D.K.2
Fox, T.3
Sivaraman, J.4
Cygler, M.5
Mort, J.S.6
Storer, A.C.7
-
32
-
-
0033579959
-
The crystal structure of human procathepsin K
-
LaLonde JM, et al. The crystal structure of human procathepsin K. Biochemistry. 1999;38(3):862-869.
-
(1999)
Biochemistry
, vol.38
, Issue.3
, pp. 862-869
-
-
LaLonde, J.M.1
-
33
-
-
0034723144
-
Crystal structure of human procathepsin X: A cysteine protease with the proregion covalently linked to the active site cysteine
-
Sivaraman J, Nagler DK, Zhang R, Menard R, Cygler M. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J Mol Biol. 2000;295(4):939-951.
-
(2000)
J Mol Biol
, vol.295
, Issue.4
, pp. 939-951
-
-
Sivaraman, J.1
Nagler, D.K.2
Zhang, R.3
Menard, R.4
Cygler, M.5
-
34
-
-
33751103711
-
The crystal structure of a Cys25 -> Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions
-
Kaulmann G, Palm GJ, Schilling K, Hilgenfeld R, Wiederanders B. The crystal structure of a Cys25 -> Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions. Protein Sci. 2006;15(11):2619-2629.
-
(2006)
Protein Sci
, vol.15
, Issue.11
, pp. 2619-2629
-
-
Kaulmann, G.1
Palm, G.J.2
Schilling, K.3
Hilgenfeld, R.4
Wiederanders, B.5
-
35
-
-
0028309017
-
The proregion of cathepsin L is required for proper folding, stability, and ER exit
-
DOI 10.1006/abbi.1994.1203
-
Tao K, Stearns NA, Dong J, Wu QL, Sahagian GG. The proregion of cathepsin L is required for proper folding, stability, and ER exit. Arch Biochem Biophys. 1994;311(1):19-27. (Pubitemid 24190097)
-
(1994)
Archives of Biochemistry and Biophysics
, vol.311
, Issue.1
, pp. 19-27
-
-
Tao, K.1
Stearns, N.A.2
Dong, J.3
Wu, Q.-L.4
Sahagian, G.G.5
-
36
-
-
0028905069
-
Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing
-
Vernet T, et al. Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing. J Biol Chem. 1995;270(18):10838-10846.
-
(1995)
J Biol Chem
, vol.270
, Issue.18
, pp. 10838-10846
-
-
Vernet, T.1
-
37
-
-
0034117738
-
An evolutionarily conserved tripartite tryptophan motif stabilizes the prodomains of cathepsin L-like cysteine proteases
-
Kreusch S, et al. An evolutionarily conserved tripartite tryptophan motif stabilizes the prodomains of cathepsin L-like cysteine proteases. Eur J Biochem. 2000;267(10):2965-2972.
-
(2000)
Eur J Biochem
, vol.267
, Issue.10
, pp. 2965-2972
-
-
Kreusch, S.1
-
38
-
-
0034941496
-
Folding incompetence of cathepsin L-like cysteine proteases may be compensated by the highly conserved, domain-building N-terminal extension of the proregion
-
DOI 10.1515/BC.2001.105
-
Schilling K, Pietschmann S, Fehn M, Wenz I, Wiederanders B. Folding incompetence of cathepsin L-like cysteine proteases may be compensated by the highly conserved, domain-building N-terminal extension of the proregion. Biol Chem. 2001;382(5):859-865. (Pubitemid 32631726)
-
(2001)
Biological Chemistry
, vol.382
, Issue.5
, pp. 859-865
-
-
Schilling, K.1
Pietschmann, S.2
Fehn, M.3
Wenz, I.4
Wiederanders, B.5
-
39
-
-
0025043421
-
Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen
-
DOI 10.1016/0092-8674(90)90161-7
-
Baranski TJ, Faust PL, Kornfeld S. Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen. Cell. 1990;63(2):281-291. (Pubitemid 20355449)
-
(1990)
Cell
, vol.63
, Issue.2
, pp. 281-291
-
-
Baranski, T.J.1
Faust, P.L.2
Kornfeld, S.3
-
41
-
-
0028334216
-
Noncovalent complexes between the lysosomal proteinase cathepsin B and its propeptide account for stable, extracellular, high molecular mass forms of the enzyme
-
Mach L, Mort JS, Glossl J. Noncovalent complexes between the lysosomal proteinase cathepsin B and its propeptide account for stable, extracellular, high molecular mass forms of the enzyme. J Biol Chem. 1994;269(17):13036-13040.
-
(1994)
J Biol Chem
, vol.269
, Issue.17
, pp. 13036-13040
-
-
Mach, L.1
Mort, J.S.2
Glossl, J.3
-
42
-
-
0242452190
-
Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro
-
Menard R, et al. Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro. J Biol Chem. 1998;273(8):4478-4484.
-
(1998)
J Biol Chem
, vol.273
, Issue.8
, pp. 4478-4484
-
-
Menard, R.1
-
43
-
-
0037175388
-
Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells
-
Jaiswal JK, Andrews NW, Simon SM. Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells. J Cell Biol. 2002;159(4):625-635.
-
(2002)
J Cell Biol
, vol.159
, Issue.4
, pp. 625-635
-
-
Jaiswal, J.K.1
Andrews, N.W.2
Simon, S.M.3
-
44
-
-
0035958557
-
2+-regulated exocytosis of lysosomes
-
DOI 10.1016/S0092-8674(01)00421-4
-
Reddy A, Caler EV, Andrews NW. Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes. Cell. 2001;106(2):157-169. (Pubitemid 32772627)
-
(2001)
Cell
, vol.106
, Issue.2
, pp. 157-169
-
-
Reddy, A.1
Caler, E.V.2
Andrews, N.W.3
-
45
-
-
4644267867
-
Exon skipping of cathepsin B: Mitochondrial targeting of a lysosomal peptidase provokes cell death
-
Muntener K, Zwicky R, Csucs G, Rohrer J, Baici A. Exon skipping of cathepsin B: mitochondrial targeting of a lysosomal peptidase provokes cell death. J Biol Chem. 2004;279(39):41012-41017.
-
(2004)
J Biol Chem
, vol.279
, Issue.39
, pp. 41012-41017
-
-
Muntener, K.1
Zwicky, R.2
Csucs, G.3
Rohrer, J.4
Baici, A.5
-
46
-
-
0038824700
-
Toward computer-based cleavage site prediction of cysteine endopeptidases
-
Lohmuller T, et al. Toward computer-based cleavage site prediction of cysteine endopeptidases. Biol Chem. 2003;384(6):899-909.
-
(2003)
Biol Chem
, vol.384
, Issue.6
, pp. 899-909
-
-
Lohmuller, T.1
-
47
-
-
0002616496
-
Über die Selbstverdauung des menschlichen Pankreas
-
Chiari H. Über die Selbstverdauung des menschlichen Pankreas. Zeitschrift für Heilkunde. 1896;17:69-96.
-
(1896)
Zeitschrift für Heilkunde
, vol.17
, pp. 69-96
-
-
Chiari, H.1
-
48
-
-
70350225542
-
Chronic pancreatitis: Genetics and pathogenesis
-
Chen JM, Ferec C. Chronic pancreatitis: genetics and pathogenesis. Annu Rev Genomics Hum Genet. 2009;10:63-87.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 63-87
-
-
Chen, J.M.1
Ferec, C.2
-
50
-
-
0023904236
-
Possible lysosomal activation of pancreatic zymogens. Activation of both human trypsinogens by cathepsin B and spontaneous acid. Activation of human trypsinogen 1
-
Figarella C, Miszczuk-Jamska B, Barrett AJ. Possible lysosomal activation of pancreatic zymogens. Activation of both human trypsinogens by cathepsin B and spontaneous acid. Activation of human trypsinogen 1. Biol Chem Hoppe Seyler. 1988;369 suppl:293-298.
-
(1988)
Biol Chem Hoppe Seyler
, vol.369
, Issue.SUPPL.
, pp. 293-298
-
-
Figarella, C.1
Miszczuk-Jamska, B.2
Barrett, A.J.3
-
51
-
-
0017107996
-
Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin
-
Bode W, Huber R. Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin. FEBS Lett. 1976;68(2):231-236.
-
(1976)
FEBS Lett
, vol.68
, Issue.2
, pp. 231-236
-
-
Bode, W.1
Huber, R.2
-
52
-
-
0036720909
-
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity
-
Van Acker GJ, Saluja AK, Bhagat L, Singh VP, Song AM, Steer ML. Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity. Am J Physiol Gastrointest Liver Physiol. 2002;283(3):G794-G800.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
, Issue.3
-
-
Van Acker, G.J.1
Saluja, A.K.2
Bhagat, L.3
Singh, V.P.4
Song, A.M.5
Steer, M.L.6
-
53
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W, et al. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest. 2000;106(6):773-781.
-
(2000)
J Clin Invest
, vol.106
, Issue.6
, pp. 773-781
-
-
Halangk, W.1
-
54
-
-
33646442373
-
Co-localization hypothesis: A mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis
-
van Acker GJ, Perides G, Steer ML. Co-localization hypothesis: a mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis. World J Gastroenterol. 2006;12(13):1985- 1990.
-
(2006)
World J Gastroenterol
, vol.12
, Issue.13
, pp. 1985-1990
-
-
Van Acker, G.J.1
Perides, G.2
Steer, M.L.3
-
55
-
-
0028937646
-
Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum
-
Lerch MM, Saluja AK, Runzi M, Dawra R, Steer ML. Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum. J Clin Invest. 1995;95(5):2222-2231.
-
(1995)
J Clin Invest
, vol.95
, Issue.5
, pp. 2222-2231
-
-
Lerch, M.M.1
Saluja, A.K.2
Runzi, M.3
Dawra, R.4
Steer, M.L.5
-
56
-
-
0038215389
-
Pericellular cathepsin B and malignant progression
-
Roshy S, Sloane BF, Moin K. Pericellular cathepsin B and malignant progression. Cancer Metastasis Rev. 2003;22(2-3):271-286.
-
(2003)
Cancer Metastasis Rev
, vol.22
, Issue.2-3
, pp. 271-286
-
-
Roshy, S.1
Sloane, B.F.2
Moin, K.3
-
57
-
-
41149103075
-
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones
-
DOI 10.1146/annurev.pharmtox.48.113006.094812
-
Hook V, Funkelstein L, Lu D, Bark S, Wegrzyn J, Hwang SR. Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu Rev Pharmacol Toxicol. 2008;48:393-423. (Pubitemid 351738159)
-
(2008)
Annual Review of Pharmacology and Toxicology
, vol.48
, pp. 393-423
-
-
Hook, V.1
Funkelstein, L.2
Lu, D.3
Bark, S.4
Wegrzyn, J.5
Hwang, S.-R.6
-
58
-
-
0042924384
-
Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter
-
Yasothornsrikul S, et al. Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter. Proc Natl Acad Sci U S A. 2003;100(16):9590-9595.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.16
, pp. 9590-9595
-
-
Yasothornsrikul, S.1
-
59
-
-
34248177365
-
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion
-
Hwang SR, et al. Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion. J Biol Chem. 2007;282(13):9556-9563.
-
(2007)
J Biol Chem
, vol.282
, Issue.13
, pp. 9556-9563
-
-
Hwang, S.R.1
-
60
-
-
70449426665
-
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
-
Mareninova OA, et al. Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest. 2009;119(11):3340-3355.
-
(2009)
J Clin Invest
, vol.119
, Issue.11
, pp. 3340-3355
-
-
Mareninova, O.A.1
-
61
-
-
69449093622
-
Mammalian macroautophagy at a glance
-
Ravikumar B, et al. Mammalian macroautophagy at a glance. J Cell Sci. 2009;122(pt 11):1707-1711.
-
(2009)
J Cell Sci
, vol.122
, Issue.PART 11
, pp. 1707-1711
-
-
Ravikumar, B.1
-
62
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
DOI 10.1038/nrm1983, PII NRM1983
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol. 2006;7(8):589-600. (Pubitemid 44325350)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.8
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
63
-
-
41449086790
-
Cardiac plasticity
-
Hill JA, Olson EN. Cardiac plasticity. N Engl J Med. 2008;358(13):1370- 1380.
-
(2008)
N Engl J Med
, vol.358
, Issue.13
, pp. 1370-1380
-
-
Hill, J.A.1
Olson, E.N.2
-
64
-
-
17044440789
-
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
-
Nishino I, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature. 2000;406(6798):906-910.
-
(2000)
Nature
, vol.406
, Issue.6798
, pp. 906-910
-
-
Nishino, I.1
-
65
-
-
63349109161
-
Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy
-
Maron BJ, et al. Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA. 2009;301(12):1253-1259.
-
(2009)
JAMA
, vol.301
, Issue.12
, pp. 1253-1259
-
-
Maron, B.J.1
-
66
-
-
19244384656
-
Accumulation of autophagic vacuoles and cardiomyopathy LAMP-2-deficient mice
-
DOI 10.1038/35022595
-
Tanaka Y, et al. Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature. 2000;406(6798):902-906. (Pubitemid 30664267)
-
(2000)
Nature
, vol.406
, Issue.6798
, pp. 902-906
-
-
Tanaka, Y.1
Guhde, G.2
Suter, A.3
Eskelinen, E.-L.4
Hartmann, D.5
Lullmann-Rauch, R.6
Janssen, P.M.L.7
Blanz, J.8
Von Figura, K.9
Saftig, P.10
-
67
-
-
32144447173
-
Rational design and applications of a Rac GTPase-specific small molecule inhibitor
-
Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y. Rational design and applications of a Rac GTPase-specific small molecule inhibitor. Methods Enzymol. 2006;406:554-565.
-
(2006)
Methods Enzymol
, vol.406
, pp. 554-565
-
-
Akbar, H.1
Cancelas, J.2
Williams, D.A.3
Zheng, J.4
Zheng, Y.5
-
68
-
-
33750246799
-
Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure
-
Cheng XW, et al. Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension. 2006;48(5):979-987.
-
(2006)
Hypertension
, vol.48
, Issue.5
, pp. 979-987
-
-
Cheng, X.W.1
-
69
-
-
18344376711
-
Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L
-
DOI 10.1073/pnas.092637699
-
Stypmann J, et al. Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. Proc Natl Acad Sci U S A. 2002;99(9):6234-6239. (Pubitemid 34493295)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.9
, pp. 6234-6239
-
-
Stypmann, J.1
Glaser, K.2
Roth, W.3
Tobin, D.J.4
Petermann, I.5
Matthias, R.6
Monnig, G.7
Haverkamp, W.8
Breithardt, G.9
Schmahl, W.10
Peters, C.11
Reinheckel, T.12
-
70
-
-
33845652579
-
Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice
-
Petermann I, et al. Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice. FASEB J. 2006;20(8):1266-1268.
-
(2006)
FASEB J
, vol.20
, Issue.8
, pp. 1266-1268
-
-
Petermann, I.1
-
71
-
-
60549104999
-
Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling
-
Tang Q, et al. Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling. J Mol Med. 2009;87(3):249-260.
-
(2009)
J Mol Med
, vol.87
, Issue.3
, pp. 249-260
-
-
Tang, Q.1
-
72
-
-
24344505388
-
The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling
-
Reinheckel T, et al. The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling. J Cell Sci. 2005;118(pt 15):3387-3395.
-
(2005)
J Cell Sci
, vol.118
, Issue.PART 15
, pp. 3387-3395
-
-
Reinheckel, T.1
-
73
-
-
77955956764
-
Impaired turnover of autophagolysosomes in cathepsin L deficiency
-
Dennemarker J, et al. Impaired turnover of autophagolysosomes in cathepsin L deficiency. Biol Chem. 2010;391(8):913-922.
-
(2010)
Biol Chem
, vol.391
, Issue.8
, pp. 913-922
-
-
Dennemarker, J.1
-
74
-
-
77949656494
-
Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
-
Dennemarker J, et al. Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis. Oncogene. 2010;29(11):1611-1621.
-
(2010)
Oncogene
, vol.29
, Issue.11
, pp. 1611-1621
-
-
Dennemarker, J.1
-
75
-
-
37549072689
-
Cell type-specific functions of the lysosomal protease cathepsin L in the heart
-
Spira D, et al. Cell type-specific functions of the lysosomal protease cathepsin L in the heart. J Biol Chem. 2007;282(51):37045-37052.
-
(2007)
J Biol Chem
, vol.282
, Issue.51
, pp. 37045-37052
-
-
Spira, D.1
-
76
-
-
33748042274
-
Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: Differences between calvaria and long bone
-
Everts V, et al. Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone. J Bone Miner Res. 2006;21(9):1399-1408.
-
(2006)
J Bone Miner Res
, vol.21
, Issue.9
, pp. 1399-1408
-
-
Everts, V.1
-
77
-
-
0034653421
-
Secreted cathepsin L generates endostatin from collagen XVIII
-
Felbor U, Dreier L, Bryant RA, Ploegh HL, Olsen BR, Mothes W. Secreted cathepsin L generates endostatin from collagen XVIII. EMBO J. 2000; 19(6):1187-1194.
-
(2000)
EMBO J
, vol.19
, Issue.6
, pp. 1187-1194
-
-
Felbor, U.1
Dreier, L.2
Bryant, R.A.3
Ploegh, H.L.4
Olsen, B.R.5
Mothes, W.6
-
78
-
-
0024263314
-
A comparison of four cathepsins (B, L, N and S) with collagenolytic activity from rabbit spleen
-
Maciewicz RA, Etherington DJ. A comparison of four cathepsins (B, L, N and S) with collagenolytic activity from rabbit spleen. Biochem J. 1988;256(2):433-440.
-
(1988)
Biochem J
, vol.256
, Issue.2
, pp. 433-440
-
-
Maciewicz, R.A.1
Etherington, D.J.2
-
79
-
-
70349437384
-
Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix
-
Schenke-Layland K, et al. Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. Eur Heart J. 2009;30(18):2254-2265.
-
(2009)
Eur Heart J
, vol.30
, Issue.18
, pp. 2254-2265
-
-
Schenke-Layland, K.1
-
80
-
-
54149103668
-
Homing and engraftment of progenitor cells: A prerequisite for cell therapy
-
Chavakis E, Urbich C, Dimmeler S. Homing and engraftment of progenitor cells: a prerequisite for cell therapy. J Mol Cell Cardiol. 2008;45(4):514-522.
-
(2008)
J Mol Cell Cardiol
, vol.45
, Issue.4
, pp. 514-522
-
-
Chavakis, E.1
Urbich, C.2
Dimmeler, S.3
-
81
-
-
74949106772
-
Enhancing the outcome of cell therapy for cardiac repair: Progress from bench to bedside and back
-
Chavakis E, Koyanagi M, Dimmeler S. Enhancing the outcome of cell therapy for cardiac repair: progress from bench to bedside and back. Circulation. 2010;121(2):325-335.
-
(2010)
Circulation
, vol.121
, Issue.2
, pp. 325-335
-
-
Chavakis, E.1
Koyanagi, M.2
Dimmeler, S.3
-
82
-
-
20044373820
-
Cathepsin L is required for endothelial progenitor cell-induced neovascularization
-
DOI 10.1038/nm1182
-
Urbich C, et al. Cathepsin L is required for endothelial progenitor cell-induced neovascularization. Nat Med. 2005;11(2):206-213. (Pubitemid 40321357)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 206-213
-
-
Urbich, C.1
Heeschen, C.2
Aicher, A.3
Sasaki, K.-I.4
Bruhl, T.5
Farhadi, M.R.6
Vajkoczy, P.7
Hofmann, W.K.8
Peters, C.9
Pennacchio, L.A.10
Abolmaali, N.D.11
Chavakis, E.12
Reinheckel, T.13
Zeiher, A.M.14
Dimmeler, S.15
-
83
-
-
50449084774
-
High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells
-
Urbich C, Dernbach E, Rossig L, Zeiher AM, Dimmeler S. High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells. J Mol Cell Cardiol. 2008;45(3):429-436.
-
(2008)
J Mol Cell Cardiol
, vol.45
, Issue.3
, pp. 429-436
-
-
Urbich, C.1
Dernbach, E.2
Rossig, L.3
Zeiher, A.M.4
Dimmeler, S.5
-
84
-
-
0034126357
-
Getting a foothold in nephrotic syndrome
-
Somlo S, Mundel P. Getting a foothold in nephrotic syndrome. Nat Genet. 2000;24(4):333-335.
-
(2000)
Nat Genet
, vol.24
, Issue.4
, pp. 333-335
-
-
Somlo, S.1
Mundel, P.2
-
85
-
-
0034051681
-
Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis
-
Kaplan JM, et al. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. Nat Genet. 2000;24(3):251-256.
-
(2000)
Nat Genet
, vol.24
, Issue.3
, pp. 251-256
-
-
Kaplan, J.M.1
-
86
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein - Nephrin - Is mutated in congenital nephrotic syndrome
-
Kestila M, et al. Positionally cloned gene for a novel glomerular protein - nephrin - is mutated in congenital nephrotic syndrome. Mol Cell. 1998;1(4):575-582.
-
(1998)
Mol Cell
, vol.1
, Issue.4
, pp. 575-582
-
-
Kestila, M.1
-
87
-
-
33751531864
-
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible
-
Hinkes B, et al. Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet. 2006;38(12):1397-1405.
-
(2006)
Nat Genet
, vol.38
, Issue.12
, pp. 1397-1405
-
-
Hinkes, B.1
-
88
-
-
0034034757
-
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
-
DOI 10.1038/74166
-
Boute N, et al. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat Genet. 2000;24(4):349-354. (Pubitemid 30187431)
-
(2000)
Nature Genetics
, vol.24
, Issue.4
, pp. 349-354
-
-
Boute, N.1
Gribouval, O.2
Roselli, S.3
Benessy, F.4
Lee, H.5
Fuchshuber, A.6
Dahan, K.7
Gubler, M.-C.8
Niaudet, P.9
Antignac, C.10
-
89
-
-
20844461826
-
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
-
Winn MP, et al. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science. 2005;308(5729):1801-1804.
-
(2005)
Science
, vol.308
, Issue.5729
, pp. 1801-1804
-
-
Winn, M.P.1
-
90
-
-
22844436647
-
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
-
Reiser J, et al. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005;37(7):739-744.
-
(2005)
Nat Genet
, vol.37
, Issue.7
, pp. 739-744
-
-
Reiser, J.1
-
91
-
-
73349132341
-
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis
-
Brown EJ, et al. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis. Nat Genet. 2010;42(1):72-76.
-
(2010)
Nat Genet
, vol.42
, Issue.1
, pp. 72-76
-
-
Brown, E.J.1
-
92
-
-
77949541746
-
Proteinuria: An enzymatic disease of the podocyte?
-
Mundel P, Reiser J. Proteinuria: an enzymatic disease of the podocyte? Kidney Int. 2010;77(7):571-580.
-
(2010)
Kidney Int
, vol.77
, Issue.7
, pp. 571-580
-
-
Mundel, P.1
Reiser, J.2
-
93
-
-
0033536599
-
Congenital nephrotic syndrome in mice lacking CD2-associated protein
-
Shih NY, et al. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science. 1999;286(5438):312-315.
-
(1999)
Science
, vol.286
, Issue.5438
, pp. 312-315
-
-
Shih, N.Y.1
-
94
-
-
0028792065
-
p125FAK tyrosine phosphorylation and focal adhesion assembly: Studies with phosphotyrosine phosphatase inhibitors
-
Defilippi P, et al. p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors. Exp Cell Res. 1995;221(1):141-152.
-
(1995)
Exp Cell Res
, vol.221
, Issue.1
, pp. 141-152
-
-
Defilippi, P.1
-
95
-
-
0034572830
-
Three ways to make a vesicle
-
Kirchhausen T. Three ways to make a vesicle. Nat Rev Mol Cell Biol. 2000;1(3):187-198.
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, Issue.3
, pp. 187-198
-
-
Kirchhausen, T.1
-
96
-
-
3142707203
-
Regulating actin dynamics at membranes: A focus on dynamin
-
Schafer DA. Regulating actin dynamics at membranes: a focus on dynamin. Traffic. 2004;5(7):463-469.
-
(2004)
Traffic
, vol.5
, Issue.7
, pp. 463-469
-
-
Schafer, D.A.1
-
97
-
-
2442453767
-
Calcineurin: A central controller of signalling in eukaryotes
-
Aramburu J, Heitman J, Crabtree GR. Calcineurin: a central controller of signalling in eukaryotes. EMBO Rep. 2004;5(4):343-348.
-
(2004)
EMBO Rep
, vol.5
, Issue.4
, pp. 343-348
-
-
Aramburu, J.1
Heitman, J.2
Crabtree, G.R.3
-
98
-
-
0036234543
-
NFAT signaling: Choreographing the social lives of cells
-
Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 2002;109 suppl:S67-S79.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Crabtree, G.R.1
Olson, E.N.2
-
99
-
-
23744484424
-
Treatment of focal segmental glomerulosclerosis
-
Meyrier A. Treatment of focal segmental glomerulosclerosis. Expert Opin Pharmacother. 2005;6(9):1539-1549.
-
(2005)
Expert Opin Pharmacother
, vol.6
, Issue.9
, pp. 1539-1549
-
-
Meyrier, A.1
-
100
-
-
0016266173
-
Pathogenesis of lipoid nephrosis: A disorder of T-cell function
-
Shalhoub RJ. Pathogenesis of lipoid nephrosis: a disorder of T-cell function. Lancet. 1974;2(7880):556-560.
-
(1974)
Lancet
, vol.2
, Issue.7880
, pp. 556-560
-
-
Shalhoub, R.J.1
-
101
-
-
33745082478
-
Minimal change nephrotic syndrome and classical Hodgkin's lymphoma: Report of 21 cases and review of the literature
-
DOI 10.1038/sj.ki.5000341, PII 5000341
-
Audard V, et al. Minimal change nephrotic syndrome and classical Hodgkin's lymphoma: report of 21 cases and review of the literature. Kidney Int. 2006;69(12):2251-2260. (Pubitemid 43882113)
-
(2006)
Kidney International
, vol.69
, Issue.12
, pp. 2251-2260
-
-
Audard, V.1
Larousserie, F.2
Grimbert, P.3
Abtahi, M.4
Sotto, J.-J.5
Delmer, A.6
Boue, F.7
Nochy, D.8
Brousse, N.9
Delarue, R.10
Remy, P.11
Ronco, P.12
Sahali, D.13
Lang, P.14
Hermine, O.15
-
102
-
-
33846456191
-
Cyclosporin therapy in patients with Alport syndrome
-
DOI 10.1007/s00467-006-0227-y
-
Charbit M, Gubler MC, Dechaux M, Gagnadoux MF, Grunfeld JP, Niaudet P. Cyclosporin therapy in patients with Alport syndrome. Pediatr Nephrol. 2007;22(1):57-63. (Pubitemid 46138361)
-
(2007)
Pediatric Nephrology
, vol.22
, Issue.1
, pp. 57-63
-
-
Charbit, M.1
Gubler, M.-C.2
Dechaux, M.3
Gagnadoux, M.-F.4
Grunfeld, J.-P.5
Niaudet, P.6
-
103
-
-
0347418134
-
Cyclosporine a slows the progressive renal disease of Alport syndrome (X-linked hereditary nephritis): Results from a canine model
-
DOI 10.1097/01.ASN.0000046964.15831.16
-
Chen D, et al. Cyclosporine a slows the progressive renal disease of alport syndrome (X-linked hereditary nephritis): results from a canine model. J Am Soc Nephrol. 2003;14(3):690-698. (Pubitemid 36246013)
-
(2003)
Journal of the American Society of Nephrology
, vol.14
, Issue.3
, pp. 690-698
-
-
Chen, D.1
Jefferson, B.2
Harvey, S.J.3
Zheng, K.4
Gartley, C.J.5
Jacobs, R.M.6
Thorner, P.S.7
-
104
-
-
33748929299
-
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function
-
Heit JJ, et al. Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function. Nature. 2006;443(7109):345-349.
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 345-349
-
-
Heit, J.J.1
-
105
-
-
38649106497
-
NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells
-
Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells. Cell. 2008;132(2):299-310.
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 299-310
-
-
Horsley, V.1
Aliprantis, A.O.2
Polak, L.3
Glimcher, L.H.4
Fuchs, E.5
-
106
-
-
34248166505
-
Polycystic kidney disease
-
Igarashi P, Somlo S. Polycystic kidney disease. J Am Soc Nephrol. 2007;18(5):1371-1373.
-
(2007)
J Am Soc Nephrol
, vol.18
, Issue.5
, pp. 1371-1373
-
-
Igarashi, P.1
Somlo, S.2
-
107
-
-
40649109025
-
The multiple roles of CUX1: Insights from mouse models and cell-based assays
-
Sansregret L, Nepveu A. The multiple roles of CUX1: insights from mouse models and cell-based assays. Gene. 2008;412(1-2):84-94.
-
(2008)
Gene
, vol.412
, Issue.1-2
, pp. 84-94
-
-
Sansregret, L.1
Nepveu, A.2
-
109
-
-
17944366493
-
Structure of human dipeptidyl peptidase I (cathepsin C): Exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases
-
DOI 10.1093/emboj/20.23.6570
-
Turk D, et al. Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J. 2001;20(23):6570-6582. (Pubitemid 33134188)
-
(2001)
EMBO Journal
, vol.20
, Issue.23
, pp. 6570-6582
-
-
Turk, D.1
Janjic, V.2
Stern, I.3
Podobnik, M.4
Lamba, D.5
Dahl, S.W.6
Lauritzen, C.7
Pedersen, J.8
Turk, V.9
Turk, B.10
-
110
-
-
0024312845
-
Biosynthesis of lysosomal endopeptidases
-
Erickson AH. Biosynthesis of lysosomal endopeptidases. J Cell Biochem. 1989;40(1):31-41.
-
(1989)
J Cell Biochem
, vol.40
, Issue.1
, pp. 31-41
-
-
Erickson, A.H.1
-
111
-
-
0033610853
-
The collagenolytic activity of cathepsin K is unique among mammalian proteinases
-
DOI 10.1074/jbc.273.48.32347
-
Garnero P, et al. The collagenolytic activity of cathepsin K is unique among mammalian proteinases. J Biol Chem. 1998;273(48):32347-32352. (Pubitemid 29177183)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.48
, pp. 32347-32352
-
-
Garnero, P.1
Borel, O.2
Byrjalsen, I.3
Ferreras, M.4
Drake, F.H.5
McQueney, M.S.6
Foged, N.T.7
Delmas, P.D.8
Delaisse, J.-M.9
-
112
-
-
43049127731
-
Emerging functions of placental cathepsins
-
Mason RW. Emerging functions of placental cathepsins. Placenta. 2008;29(5):385-390.
-
(2008)
Placenta
, vol.29
, Issue.5
, pp. 385-390
-
-
Mason, R.W.1
-
113
-
-
67749118106
-
Design of selective Cathepsin inhibitors
-
Bethel PA, et al. Design of selective Cathepsin inhibitors. Bioorg Med Chem Lett. 2009;19(16):4622-4625.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.16
, pp. 4622-4625
-
-
Bethel, P.A.1
-
114
-
-
34548492784
-
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis
-
Viken MK, et al. Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis. Hum Immunol. 2007;68(9):748-755.
-
(2007)
Hum Immunol
, vol.68
, Issue.9
, pp. 748-755
-
-
Viken, M.K.1
-
115
-
-
33845740609
-
Colocalization of cystatin M/E and cathepsin V in lamellar granules and corneodesmosomes suggests a functional role in epidermal differentiation
-
Zeeuwen PL, et al. Colocalization of cystatin M/E and cathepsin V in lamellar granules and corneodesmosomes suggests a functional role in epidermal differentiation. J Invest Dermatol. 2007;127(1):120-128.
-
(2007)
J Invest Dermatol
, vol.127
, Issue.1
, pp. 120-128
-
-
Zeeuwen, P.L.1
-
116
-
-
33645026707
-
Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia
-
Haider AS, et al. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. J Invest Dermatol. 2006;126(4):869-881.
-
(2006)
J Invest Dermatol
, vol.126
, Issue.4
, pp. 869-881
-
-
Haider, A.S.1
-
117
-
-
12344271817
-
The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles
-
DOI 10.1078/0171-9335-00404
-
Hagemann S, et al. The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles. Eur J Cell Biol. 2004;83(11-12):775-780. (Pubitemid 40123841)
-
(2004)
European Journal of Cell Biology
, vol.83
, Issue.11-12
, pp. 775-780
-
-
Hagemann, S.1
Gunther, T.2
Dennemarker, J.3
Luhmuller, T.4
Bromme, D.5
Schule, R.6
Peters, C.7
Reinheckel, T.8
-
118
-
-
33746255613
-
Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice
-
DOI 10.1515/BC.2006.112, PII BCHM3877885
-
Sevenich L, Pennacchio LA, Peters C, Reinheckel T. Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice. Biol Chem. 2006;387(7):885-891. (Pubitemid 44100235)
-
(2006)
Biological Chemistry
, vol.387
, Issue.7
, pp. 885-891
-
-
Sevenich, L.1
Pennacchio, L.A.2
Peters, C.3
Reinheckel, T.4
-
119
-
-
0032709548
-
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis
-
Toomes C, et al. Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis. Nat Genet. 1999;23(4):421-424.
-
(1999)
Nat Genet
, vol.23
, Issue.4
, pp. 421-424
-
-
Toomes, C.1
-
120
-
-
0033587689
-
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo
-
Pham CT, Ley TJ. Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proc Natl Acad Sci U S A. 1999;96(15):8627-8632.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.15
, pp. 8627-8632
-
-
Pham, C.T.1
Ley, T.J.2
-
121
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
-
DOI 10.1073/pnas.95.23.13453
-
Saftig P, et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc Natl Acad Sci U S A. 1998;95(23):13453-13458. (Pubitemid 28522993)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.23
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
Jones, S.4
Boyde, A.5
Rommerskirch, W.6
Moritz, J.D.7
Schu, P.8
Von Figura, K.9
-
122
-
-
0032859323
-
Cathepsin K knockout mice develop osteopetrosis due to a deficit in matrix degradation but not demineralization
-
DOI 10.1359/jbmr.1999.14.10.1654
-
Gowen M, et al. Cathepsin K knockout mice develop osteopetrosis due to a deficit in matrix degradation but not demineralization. J Bone Miner Res. 1999;14(10):1654-1663. (Pubitemid 29455813)
-
(1999)
Journal of Bone and Mineral Research
, vol.14
, Issue.10
, pp. 1654-1663
-
-
Gowen, M.1
Lazner, F.2
Dodds, R.3
Kapadia, R.4
Feild, J.5
Tavaria, M.6
Bertoncello, I.7
Drake, F.8
Zavarselk, S.9
Tellis, I.10
Hertzog, P.11
Debouck, C.12
Kola, I.13
-
123
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
Gelb BD, Shi GP, Chapman HA, Desnick RJ. Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science. 1996;273(5279):1236-1238.
-
(1996)
Science
, vol.273
, Issue.5279
, pp. 1236-1238
-
-
Gelb, B.D.1
Shi, G.P.2
Chapman, H.A.3
Desnick, R.J.4
-
124
-
-
2542586967
-
Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy
-
Potts W, et al. Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy. Int J Exp Pathol. 2004;85(2):85-96.
-
(2004)
Int J Exp Pathol
, vol.85
, Issue.2
, pp. 85-96
-
-
Potts, W.1
-
125
-
-
34247190780
-
Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice
-
DOI 10.1161/CIRCULATIONAHA.107.688523
-
Kitamoto S, et al. Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice. Circulation. 2007;115(15):2065-2075. (Pubitemid 46625958)
-
(2007)
Circulation
, vol.115
, Issue.15
, pp. 2065-2075
-
-
Kitamoto, S.1
Sukhova, G.K.2
Sun, J.3
Yang, M.4
Libby, P.5
Love, V.6
Duramad, P.7
Sun, C.8
Zhang, Y.9
Yang, X.10
Peters, C.11
Shi, G.-P.12
-
126
-
-
33644865170
-
Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation
-
Lutgens E, et al. Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation. Circulation. 2006;113(1):98-107.
-
(2006)
Circulation
, vol.113
, Issue.1
, pp. 98-107
-
-
Lutgens, E.1
-
127
-
-
0037362831
-
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice
-
DOI 10.1172/JCI200314915
-
Sukhova GK, et al. Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2003;111(6):897-906. (Pubitemid 37074965)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.6
, pp. 897-906
-
-
Sukhova, G.K.1
Zhang, Y.2
Pan, J.-H.3
Wada, Y.4
Yamamoto, T.5
Naito, M.6
Kodama, T.7
Tsimikas, S.8
Witztum, J.L.9
Lu, M.L.10
Sakara, Y.11
Chin, M.T.12
Libby, P.13
Shi, G.-P.14
-
128
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva V, et al. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 2006;20(5):543-556.
-
(2006)
Genes Dev
, vol.20
, Issue.5
, pp. 543-556
-
-
Gocheva, V.1
-
129
-
-
33744917827
-
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
-
DOI 10.1158/0008-5472.CAN-05-4463
-
Vasiljeva O, et al. Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res. 2006;66(10):5242-5250. (Pubitemid 43844948)
-
(2006)
Cancer Research
, vol.66
, Issue.10
, pp. 5242-5250
-
-
Vasiljeva, O.1
Papazoglou, A.2
Kruger, A.3
Brodoefel, H.4
Korovin, M.5
Deussing, J.6
Augustin, N.7
Nielsen, B.S.8
Almholt, K.9
Bogyo, M.10
Peters, C.11
Reinheckel, T.12
-
130
-
-
3042551389
-
Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas
-
Gondi CS, et al. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004;64(12):4069-4077.
-
(2004)
Cancer Res
, vol.64
, Issue.12
, pp. 4069-4077
-
-
Gondi, C.S.1
-
131
-
-
38449089504
-
RNAi-mediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis
-
Tummalapalli P, et al. RNAi-mediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis. Int J Oncol. 2007;31(5):1039-1050.
-
(2007)
Int J Oncol
, vol.31
, Issue.5
, pp. 1039-1050
-
-
Tummalapalli, P.1
-
132
-
-
77249161680
-
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
-
Sevenich L, et al. Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. Proc Natl Acad Sci U S A. 2010;107(6):2497-2502.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.6
, pp. 2497-2502
-
-
Sevenich, L.1
-
133
-
-
76149146398
-
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
-
Gocheva V, et al. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev. 2010;24(3):241-255.
-
(2010)
Genes Dev
, vol.24
, Issue.3
, pp. 241-255
-
-
Gocheva, V.1
-
134
-
-
26444591985
-
Cathepsin L is essential for onset of autoimmune diabetes in NOD mice
-
DOI 10.1172/JCI25485
-
Maehr R, et al. Cathepsin L is essential for onset of autoimmune diabetes in NOD mice. J Clin Invest. 2005;115(10):2934-2943. (Pubitemid 41434421)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2934-2943
-
-
Maehr, R.1
Mintern, J.D.2
Herman, A.E.3
Lennon-Dumenil, A.-M.4
Mathis, D.5
Benoist, C.6
Ploegh, H.L.7
-
135
-
-
57549118164
-
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice
-
Yang M, et al. Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol. 2008;28(12):2202-2208.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.12
, pp. 2202-2208
-
-
Yang, M.1
-
136
-
-
0042821989
-
Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes
-
DOI 10.2337/diabetes.52.9.2411
-
Huang X, Vaag A, Carlsson E, Hansson M, Ahren B, Groop L. Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes. Diabetes. 2003;52(9):2411-2418. (Pubitemid 37059514)
-
(2003)
Diabetes
, vol.52
, Issue.9
, pp. 2411-2418
-
-
Huang, X.1
Vaag, A.2
Carlsson, E.3
Hansson, M.4
Ahren, B.5
Groop, L.6
-
137
-
-
31644436480
-
Cysteine cathepsins in human silicotic bronchoalveolar lavage fluids
-
DOI 10.1016/j.bbadis.2005.10.005, PII S0925443905001511
-
Perdereau C, Godat E, Maurel MC, Hazouard E, Diot E, Lalmanach G. Cysteine cathepsins in human silicotic bronchoalveolar lavage fluids. Biochim Biophys Acta. 2006;1762(3):351-356. (Pubitemid 43172851)
-
(2006)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1762
, Issue.3
, pp. 351-356
-
-
Perdereau, C.1
Godat, E.2
Maurel, M.-C.3
Hazouard, E.4
Diot, E.5
Lalmanach, G.6
-
138
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008;9(8):847-856.
-
(2008)
Nat Immunol
, vol.9
, Issue.8
, pp. 847-856
-
-
Hornung, V.1
-
139
-
-
52649142110
-
Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
-
Srivastava M, et al. Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis. Respir Res. 2008;9:54.
-
(2008)
Respir Res
, vol.9
, pp. 54
-
-
Srivastava, M.1
-
140
-
-
2442694270
-
Pivotal role of cathepsin K in lung fibrosis
-
Buhling F, et al. Pivotal role of cathepsin K in lung fibrosis. Am J Pathol. 2004;164(6):2203-2216. (Pubitemid 38669366)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.6
, pp. 2203-2216
-
-
Buhling, F.1
Rocken, C.2
Brasch, F.3
Hartig, R.4
Yasuda, Y.5
Saftig, P.6
Bromme, D.7
Welte, T.8
-
141
-
-
0037215592
-
Cysteine protease activity is required for surfactant protein B processing and lamellar body genesis
-
Guttentag S, Robinson L, Zhang P, Brasch F, Buhling F, Beers M. Cysteine protease activity is required for surfactant protein B processing and lamellar body genesis. Am J Respir Cell Mol Biol. 2003;28(1):69-79.
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, Issue.1
, pp. 69-79
-
-
Guttentag, S.1
Robinson, L.2
Zhang, P.3
Brasch, F.4
Buhling, F.5
Beers, M.6
-
142
-
-
0036853166
-
Thymocyte expression of cathepsin L is essential for NKT cell development
-
Honey K, et al. Thymocyte expression of cathepsin L is essential for NKT cell development. Nat Immunol. 2002;3(11):1069-1074.
-
(2002)
Nat Immunol
, vol.3
, Issue.11
, pp. 1069-1074
-
-
Honey, K.1
-
143
-
-
0037087364
-
A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation
-
Hsieh CS, deRoos P, Honey K, Beers C, Rudensky AY. A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J Immunol. 2002;168(6):2618-2625.
-
(2002)
J Immunol
, vol.168
, Issue.6
, pp. 2618-2625
-
-
Hsieh, C.S.1
DeRoos, P.2
Honey, K.3
Beers, C.4
Rudensky, A.Y.5
-
144
-
-
0032540474
-
Cathepsin L: Critical role in Ii degradation and CD4 T cell selection in the thymus
-
Nakagawa T, et al. Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science. 1998;280(5362):450-453.
-
(1998)
Science
, vol.280
, Issue.5362
, pp. 450-453
-
-
Nakagawa, T.1
-
145
-
-
2442549710
-
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice
-
Nakagawa TY, et al. Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity. 1999;10(2):207-217.
-
(1999)
Immunity
, vol.10
, Issue.2
, pp. 207-217
-
-
Nakagawa, T.Y.1
-
146
-
-
0141831692
-
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis
-
DOI 10.1172/JCI200318028
-
Tolosa E, et al. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest. 2003;112(4):517-526. (Pubitemid 38056336)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.4
, pp. 517-526
-
-
Tolosa, E.1
Li, W.2
Yasuda, Y.3
Wienhold, W.4
Denzin, L.K.5
Lautwein, A.6
Driessen, C.7
Schnorrer, P.8
Weber, E.9
Stevanovic, S.10
Kurek, R.11
Melms, A.12
Bromme, D.13
-
147
-
-
46749086701
-
Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage
-
Dejica VM, et al. Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage. Am J Pathol. 2008;173(1):161-169.
-
(2008)
Am J Pathol
, vol.173
, Issue.1
, pp. 161-169
-
-
Dejica, V.M.1
-
148
-
-
39749117421
-
Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice
-
DOI 10.1002/art.23224
-
Schurigt U, et al. Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice. Arthritis Rheum. 2008;58(2):422-434. (Pubitemid 351294877)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.2
, pp. 422-434
-
-
Schurigt, U.1
Hummel, K.M.2
Petrow, P.K.3
Gajda, M.4
Stockigt, R.5
Middel, P.6
Zwerina, J.7
Janik, T.8
Bernhardt, R.9
Schuler, S.10
Scharnweber, D.11
Beckmann, F.12
Saftig, P.13
Kollias, G.14
Schett, G.15
Wiederanders, B.16
Brauer, R.17
-
149
-
-
65749098196
-
Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice
-
Svelander L, et al. Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice. Eur J Pharmacol. 2009;613(1-3):155-162.
-
(2009)
Eur J Pharmacol
, vol.613
, Issue.1-3
, pp. 155-162
-
-
Svelander, L.1
-
150
-
-
38849127573
-
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
-
Asagiri M, et al. Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science. 2008;319(5863):624-627.
-
(2008)
Science
, vol.319
, Issue.5863
, pp. 624-627
-
-
Asagiri, M.1
|