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Volumn 27, Issue 19, 2013, Pages 2086-2098

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis

Author keywords

Carcinogenesis; Cathepsin C; Dipeptidyl peptidase I; Fibroblasts; Leukocytes; Skin

Indexed keywords

DIPEPTIDYL PEPTIDASE I; PLATELET DERIVED GROWTH FACTOR A; SMOOTH MUSCLE ACTIN; CATHEPSIN B; CHYMASE; PANCREATIC ELASTASE;

EID: 84885337942     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.224899.113     Document Type: Article
Times cited : (73)

References (71)
  • 1
    • 0036168150 scopus 로고    scopus 로고
    • Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
    • Adkison AM, Raptis SZ, Kelley DG, Pham CT. 2002. Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest 109: 363-371.
    • (2002) J Clin Invest , vol.109 , pp. 363-371
    • Adkison, A.M.1    Raptis, S.Z.2    Kelley, D.G.3    Pham, C.T.4
  • 2
    • 84858011122 scopus 로고    scopus 로고
    • Delineating protease functions during cancer development
    • Affara NI, Andreu P, Coussens LM. 2009. Delineating protease functions during cancer development. Methods Mol Biol 539: 1-32.
    • (2009) Methods Mol Biol , vol.539 , pp. 1-32
    • Affara, N.I.1    Andreu, P.2    Coussens, L.M.3
  • 4
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill F, Charles KA, Mantovani A. 2005. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7: 211-217.
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 8
    • 0026575258 scopus 로고
    • Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues
    • Buck MR, Karustis DG, Day NA, Honn KV, Sloane BF. 1992. Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues. Biochem J 282: 273-278.
    • (1992) Biochem J , vol.282 , pp. 273-278
    • Buck, M.R.1    Karustis, D.G.2    Day, N.A.3    Honn, K.V.4    Sloane, B.F.5
  • 9
    • 0037102412 scopus 로고    scopus 로고
    • Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
    • Cheng JD, Dunbrack RL, Valianou M, Rogatko A, Alpaugh RK, Weiner LM. 2002. Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res 62: 4767-4772.
    • (2002) Cancer Res , vol.62 , pp. 4767-4772
    • Cheng, J.D.1    Dunbrack, R.L.2    Valianou, M.3    Rogatko, A.4    Alpaugh, R.K.5    Weiner, L.M.6
  • 10
    • 0029844435 scopus 로고    scopus 로고
    • Genetic predisposition and parameters of malignant progression in K14- HPV16 transgenic mice
    • Coussens LM, Hanahan D, Arbeit JM. 1996. Genetic predisposition and parameters of malignant progression in K14- HPV16 transgenic mice. Am J Pathol 149: 1899-1917.
    • (1996) Am J Pathol , vol.149 , pp. 1899-1917
    • Coussens, L.M.1    Hanahan, D.2    Arbeit, J.M.3
  • 12
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B, Matrisian LM. 2002. Matrix metalloproteinase inhibitors and cancer: Trials and tribulations. Science 295: 2387-2392.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 13
    • 0035852855 scopus 로고    scopus 로고
    • Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing
    • Dahl SW, Halkier T, Lauritzen C, Dolenc I, Pedersen J, Turk V, Turk B. 2001. Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing. Biochemistry 40: 1671-1678.
    • (2001) Biochemistry , vol.40 , pp. 1671-1678
    • Dahl, S.W.1    Halkier, T.2    Lauritzen, C.3    Dolenc, I.4    Pedersen, J.5    Turk, V.6    Turk, B.7
  • 18
    • 19344365408 scopus 로고    scopus 로고
    • De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
    • De Visser KE, Korets LV, Coussens LM. 2005. De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7: 411-423.
    • (2005) Cancer Cell , vol.7 , pp. 411-423
    • de Visser, K.E.1    Korets, L.V.2    Coussens, L.M.3
  • 19
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. 2002. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 20
    • 76349096670 scopus 로고    scopus 로고
    • Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kBdependent manner
    • Erez N, Truitt M, Olson P, Arron ST, Hanahan D. 2010. Cancerassociated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kBdependent manner. Cancer Cell 17: 135-147.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 21
    • 33846167705 scopus 로고    scopus 로고
    • Activity based probes for proteases: Applications to biomarker discovery, molecular imaging and drug screening
    • Fonovic M, Bogyo M. 2007. Activity based probes for proteases: Applications to biomarker discovery, molecular imaging and drug screening. Curr Pharm Des 13: 253-261.
    • (2007) Curr Pharm Des , vol.13 , pp. 253-261
    • Fonovic, M.1    Bogyo, M.2
  • 22
    • 8744314149 scopus 로고    scopus 로고
    • Cathepsin C involvement in the aetiology of Papillon-Lefevre syndrome
    • Frezzini C, Leao JC, Porter S. 2004. Cathepsin C involvement in the aetiology of Papillon-Lefevre syndrome. Int J Paediatr Dent 14: 466-467.
    • (2004) Int J Paediatr Dent , vol.14 , pp. 466-467
    • Frezzini, C.1    Leao, J.C.2    Porter, S.3
  • 23
    • 33846643454 scopus 로고    scopus 로고
    • Cysteine cathepsins and the cutting edge of cancer invasion
    • Gocheva V, Joyce JA. 2007. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 6: 60-64.
    • (2007) Cell Cycle , vol.6 , pp. 60-64
    • Gocheva, V.1    Joyce, J.A.2
  • 25
    • 76149146398 scopus 로고    scopus 로고
    • IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
    • Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. 2010. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev 24: 241-255.
    • (2010) Genes Dev , vol.24 , pp. 241-255
    • Gocheva, V.1    Wang, H.W.2    Gadea, B.B.3    Shree, T.4    Hunter, K.E.5    Garfall, A.L.6    Berman, T.7    Joyce, J.A.8
  • 26
    • 9144231998 scopus 로고    scopus 로고
    • RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas
    • Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS. 2004. RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas. Oncogene 23: 8486-8496.
    • (2004) Oncogene , vol.23 , pp. 8486-8496
    • Gondi, C.S.1    Lakka, S.S.2    Dinh, D.H.3    Olivero, W.C.4    Gujrati, M.5    Rao, J.S.6
  • 29
    • 77952475301 scopus 로고    scopus 로고
    • Therapeutic utility and medicinal chemistry of cathepsin C inhibitors
    • Guay D, Beaulieu C, Percival MD. 2010. Therapeutic utility and medicinal chemistry of cathepsin C inhibitors. Curr Top Med Chem 10: 708-716.
    • (2010) Curr Top Med Chem , vol.10 , pp. 708-716
    • Guay, D.1    Beaulieu, C.2    Percival, M.D.3
  • 30
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
    • Guy CT, Cardiff RD, Muller WJ. 1992. Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease. Mol Cell Biol 12: 954-961.
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 34
    • 17144394796 scopus 로고    scopus 로고
    • Multiple roles for cysteine cathep-sins in cancer
    • Joyce JA, Hanahan D. 2004. Multiple roles for cysteine cathep-sins in cancer. Cell Cycle 3: 1516-1519.
    • (2004) Cell Cycle , vol.3 , pp. 1516-1519
    • Joyce, J.A.1    Hanahan, D.2
  • 37
    • 70450265558 scopus 로고    scopus 로고
    • Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis
    • Lilla JN, Werb Z. 2010. Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis. Dev Biol 337: 124-133.
    • (2010) Dev Biol , vol.337 , pp. 124-133
    • Lilla, J.N.1    Werb, Z.2
  • 38
    • 0035911221 scopus 로고    scopus 로고
    • Colonystimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin EY, Nguyen AV, Russell RG, Pollard JW. 2001. Colonystimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193: 727-740.
    • (2001) J Exp Med , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 39
    • 0038230415 scopus 로고    scopus 로고
    • The macro-phage growth factor CSF-1 in mammary gland development and tumor progression
    • Lin E, Gouon-Evans V, Nguyen A, Pollard J. 2002. The macro-phage growth factor CSF-1 in mammary gland development and tumor progression. J Mammary Gland Biol Neoplasia 7: 147-162.
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , pp. 147-162
    • Lin, E.1    Gouon-Evans, V.2    Nguyen, A.3    Pollard, J.4
  • 40
    • 33745837774 scopus 로고    scopus 로고
    • Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
    • Loeffler M, Kruger JA, Niethammer AG, Reisfeld RA. 2006. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Invest 116: 1955-1962.
    • (2006) J Clin Invest , vol.116 , pp. 1955-1962
    • Loeffler, M.1    Kruger, J.A.2    Niethammer, A.G.3    Reisfeld, R.A.4
  • 41
    • 34648815810 scopus 로고    scopus 로고
    • Emerging roles of proteases in tumour suppression
    • Lopez-Otin C, Matrisian LM. 2007. Emerging roles of proteases in tumour suppression. Nat Rev Cancer 7: 800-808.
    • (2007) Nat Rev Cancer , vol.7 , pp. 800-808
    • Lopez-Otin, C.1    Matrisian, L.M.2
  • 43
    • 79953163995 scopus 로고    scopus 로고
    • Proteolytic networks in cancer
    • Mason SD, Joyce JA. 2011. Proteolytic networks in cancer. Trends Cell Biol 21: 228-237.
    • (2011) Trends Cell Biol , vol.21 , pp. 228-237
    • Mason, S.D.1    Joyce, J.A.2
  • 45
    • 33749017931 scopus 로고    scopus 로고
    • Cysteine cathepsins: Multifunctional enzymes in cancer
    • Mohamed MM, Sloane BF. 2006. Cysteine cathepsins: Multifunctional enzymes in cancer. Nat Rev Cancer 6: 764-775.
    • (2006) Nat Rev Cancer , vol.6 , pp. 764-775
    • Mohamed, M.M.1    Sloane, B.F.2
  • 46
    • 2442701902 scopus 로고    scopus 로고
    • Novel mutations in the cathepsin C gene in patients with pre-pubertal aggressive periodontitis and Papillon-Lefevre syndrome
    • Noack B, Gorgens H, Hoffmann T, Fanghanel J, Kocher T, Eickholz P, Schackert HK. 2004. Novel mutations in the cathepsin C gene in patients with pre-pubertal aggressive periodontitis and Papillon-Lefevre syndrome. J Dent Res 83: 368-370.
    • (2004) J Dent Res , vol.83 , pp. 368-370
    • Noack, B.1    Gorgens, H.2    Hoffmann, T.3    Fanghanel, J.4    Kocher, T.5    Eickholz, P.6    Schackert, H.K.7
  • 48
    • 37549070672 scopus 로고    scopus 로고
    • Cysteine cathepsin proteases as pharmacological targets in cancer
    • Palermo C, Joyce JA. 2008. Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol Sci 29: 22-28.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 22-28
    • Palermo, C.1    Joyce, J.A.2
  • 49
    • 0033579444 scopus 로고    scopus 로고
    • Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
    • Park JE, Lenter MC, Zimmermann RN, Garin-Chesa P, Old LJ, Rettig WJ. 1999. Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J Biol Chem 274: 36505-36512.
    • (1999) J Biol Chem , vol.274 , pp. 36505-36512
    • Park, J.E.1    Lenter, M.C.2    Zimmermann, R.N.3    Garin-Chesa, P.4    Old, L.J.5    Rettig, W.J.6
  • 50
    • 0033587689 scopus 로고    scopus 로고
    • Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo
    • Pham CT, Ley TJ. 1999. Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proc Natl Acad Sci 96: 8627-8632.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 8627-8632
    • Pham, C.T.1    Ley, T.J.2
  • 51
    • 10344234724 scopus 로고    scopus 로고
    • Papillon-Lefevre syndrome: Correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans
    • Pham CT, Ivanovich JL, Raptis SZ, Zehnbauer B, Ley TJ. 2004. Papillon-Lefevre syndrome: Correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans. J Immunol 173: 72777281.
    • (2004) J Immunol , vol.173 , pp. 72777281
    • Pham, C.T.1    Ivanovich, J.L.2    Raptis, S.Z.3    Zehnbauer, B.4    Ley, T.J.5
  • 53
  • 54
    • 0026664252 scopus 로고
    • Rat procathepsin B. Proteolytic processing to the mature form in vitro
    • Rowan AD, Mason P, Mach L, Mort JS. 1992. Rat procathepsin B. Proteolytic processing to the mature form in vitro. J Biol Chem 267: 15993-15999.
    • (1992) J Biol Chem , vol.267 , pp. 15993-15999
    • Rowan, A.D.1    Mason, P.2    Mach, L.3    Mort, J.S.4
  • 56
    • 72849125358 scopus 로고    scopus 로고
    • Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
    • Santos AM, Jung J, Aziz N, Kissil JL, Pure E. 2009. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J Clin Invest 119: 3613-3625.
    • (2009) J Clin Invest , vol.119 , pp. 3613-3625
    • Santos, A.M.1    Jung, J.2    Aziz, N.3    Kissil, J.L.4    Pure, E.5
  • 57
    • 0028286026 scopus 로고
    • Molecular cloning of fibroblast activation protein a, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers
    • Scanlan MJ, Raj BK, Calvo B, Garin-Chesa P, Sanz-Moncasi MP, Healey JH, Old LJ, Rettig WJ. 1994. Molecular cloning of fibroblast activation protein a, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers. Proc Natl Acad Sci 91: 5657-5661.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 5657-5661
    • Scanlan, M.J.1    Raj, B.K.2    Calvo, B.3    Garin-Chesa, P.4    Sanz-Moncasi, M.P.5    Healey, J.H.6    Old, L.J.7    Rettig, W.J.8
  • 62
    • 84880656055 scopus 로고    scopus 로고
    • Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
    • Tran E, Chinnasamy D, Yu Z, Morgan RA, Lee CC, Restifo NP, Rosenberg SA. 2013. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J Exp Med 210: 1125-1135.
    • (2013) J Exp Med , vol.210 , pp. 1125-1135
    • Tran, E.1    Chinnasamy, D.2    Yu, Z.3    Morgan, R.A.4    Lee, C.C.5    Restifo, N.P.6    Rosenberg, S.A.7
  • 63
    • 33748308883 scopus 로고    scopus 로고
    • Targeting proteases: Successes, failures and future prospects
    • Turk B. 2006. Targeting proteases: Successes, failures and future prospects. Nat Rev Drug Discov 5: 785-799.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 785-799
    • Turk, B.1
  • 64
    • 0345310073 scopus 로고    scopus 로고
    • Revised definition of substrate binding sites of papain-like cysteine proteases
    • Turk D, Guncar G, Podobnik M, Turk B. 1998. Revised definition of substrate binding sites of papain-like cysteine proteases. Biol Chem 379: 137-147.
    • (1998) Biol Chem , vol.379 , pp. 137-147
    • Turk, D.1    Guncar, G.2    Podobnik, M.3    Turk, B.4
  • 65
    • 17944366493 scopus 로고    scopus 로고
    • Structure of human dipeptidyl peptidase I (cathepsin C): Exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases
    • Turk D, Janjic V, Stern I, Podobnik M, Lamba D, Dahl SW, Lauritzen C, Pedersen J, Turk V, Turk B. 2001. Structure of human dipeptidyl peptidase I (cathepsin C): Exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J 20: 6570-6582.
    • (2001) EMBO J , vol.20 , pp. 6570-6582
    • Turk, D.1    Janjic, V.2    Stern, I.3    Podobnik, M.4    Lamba, D.5    Dahl, S.W.6    Lauritzen, C.7    Pedersen, J.8    Turk, V.9    Turk, B.10
  • 66
    • 2342551977 scopus 로고    scopus 로고
    • Cysteine cathepsins (proteases)-on the main stage of cancer?
    • Turk V, Kos J, Turk B. 2004. Cysteine cathepsins (proteases)-on the main stage of cancer? Cancer Cell 5: 409-410.
    • (2004) Cancer Cell , vol.5 , pp. 409-410
    • Turk, V.1    Kos, J.2    Turk, B.3
  • 70
    • 0035947568 scopus 로고    scopus 로고
    • Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice
    • Wolters PJ, Pham CT, Muilenburg DJ, Ley TJ, Caughey GH. 2001. Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J Biol Chem 276: 18551-18566.
    • (2001) J Biol Chem , vol.276 , pp. 18551-18566
    • Wolters, P.J.1    Pham, C.T.2    Muilenburg, D.J.3    Ley, T.J.4    Caughey, G.H.5
  • 71
    • 33646594411 scopus 로고    scopus 로고
    • A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C
    • Yuan F, Verhelst SH, Blum G, Coussens LM, Bogyo M. 2006. A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C. J Am Chem Soc 128: 5616-5617.
    • (2006) J Am Chem Soc , vol.128 , pp. 5616-5617
    • Yuan, F.1    Verhelst, S.H.2    Blum, G.3    Coussens, L.M.4    Bogyo, M.5


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