Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

Gut

Volumn 61, Issue 6, 2012, Pages 877-884

  Gopinathan, Aarthi ^a,b   DeNicola, Gina M ^a,b   Frese, Kristopher K ^a   Cook, Natalie ^a   Karreth, Florian A ^a   Mayerle, Julia ^c   Lerch, Markus M ^c   Reinheckel, Thomas ^d   Tuveson, David A ^a  

^a CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF GREIFSWALD   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; GEMCITABINE; MITOGEN ACTIVATED PROTEIN KINASE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE;

ADVANCED CANCER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER SURVIVAL; CELL PROLIFERATION; CONTROLLED STUDY; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER METASTASIS; MONOTHERAPY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SINGLE DRUG DOSE; SURVIVAL RATE;

ADENOCARCINOMA; ALLELES; ANIMALS; BLOTTING, WESTERN; CARCINOMA, PANCREATIC DUCTAL; CATHEPSIN B; CATHEPSIN L; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROZYGOTE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS;

EID: 84860557204     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-300850     Document Type: Article

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