메뉴 건너뛰기




Volumn 105, Issue 6, 2008, Pages 2105-2110

A causal role for ERG in neoplastic transformation of prostate epithelium

Author keywords

ETS family; Mouse models; Prostate cancer; Prostatic intrepithelial neoplasia (PIN)

Indexed keywords

TRANSCRIPTION FACTOR ERG;

EID: 41149097040     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0711711105     Document Type: Article
Times cited : (246)

References (24)
  • 1
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, et al. (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310:644-648.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1
  • 2
    • 34447342868 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
    • Perner S, et al. (2007) TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion. Am J Surg Pathol 31:882-888.
    • (2007) Am J Surg Pathol , vol.31 , pp. 882-888
    • Perner, S.1
  • 3
    • 33749029695 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
    • Perner S, et al. (2006) TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res 66:8337-8341.
    • (2006) Cancer Res , vol.66 , pp. 8337-8341
    • Perner, S.1
  • 4
    • 34248510706 scopus 로고    scopus 로고
    • TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
    • Demichelis F, et al. (2007) TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 26:4596-4599.
    • (2007) Oncogene , vol.26 , pp. 4596-4599
    • Demichelis, F.1
  • 5
    • 20444493600 scopus 로고    scopus 로고
    • Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
    • Petrovics G, et al. (2005) Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene 24:3847-3852.
    • (2005) Oncogene , vol.24 , pp. 3847-3852
    • Petrovics, G.1
  • 6
    • 34547936357 scopus 로고    scopus 로고
    • Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: Frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues
    • Tu JJ, et al. (2007) Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: Frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues. Mod Pathol 20:921-928.
    • (2007) Mod Pathol , vol.20 , pp. 921-928
    • Tu, J.J.1
  • 7
    • 9144251970 scopus 로고    scopus 로고
    • Gene expression profiling identifies clinically relevant subtypes of prostate cancer
    • Lapointe J, et al. (2004) Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci USA 101:811-816.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 811-816
    • Lapointe, J.1
  • 9
    • 33746602208 scopus 로고    scopus 로고
    • A molecular correlate to the Gleason grading system for prostate adenocarcinoma
    • True L, et al. (2006) A molecular correlate to the Gleason grading system for prostate adenocarcinoma. Proc Natl Acad Sci USA 103:10991-10996.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10991-10996
    • True, L.1
  • 10
    • 33751260934 scopus 로고    scopus 로고
    • TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
    • Iljin K, et al. (2006) TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming. Cancer Res 66:10242-10246.
    • (2006) Cancer Res , vol.66 , pp. 10242-10246
    • Iljin, K.1
  • 11
    • 21744461721 scopus 로고    scopus 로고
    • The oncogenic TLS-ERG fusion protein exerts different effects in hematopoietic cells and fibroblasts
    • Zou J, et al. (2005) The oncogenic TLS-ERG fusion protein exerts different effects in hematopoietic cells and fibroblasts. Mol Cell Biol 25:6235-6246.
    • (2005) Mol Cell Biol , vol.25 , pp. 6235-6246
    • Zou, J.1
  • 12
    • 0037569709 scopus 로고    scopus 로고
    • PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins
    • Deneen B, et al. (2003) PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Mol Cell Biol 23:3897-3908.
    • (2003) Mol Cell Biol , vol.23 , pp. 3897-3908
    • Deneen, B.1
  • 13
    • 33747338731 scopus 로고    scopus 로고
    • Influence of surgical manipulation on prostate gene expression: Implications for molecular correlates of treatment effects and disease prognosis
    • Lin DW, et al. (2006) Influence of surgical manipulation on prostate gene expression: Implications for molecular correlates of treatment effects and disease prognosis. J Clin Oncol 24:3763-3770.
    • (2006) J Clin Oncol , vol.24 , pp. 3763-3770
    • Lin, D.W.1
  • 14
    • 5144225237 scopus 로고    scopus 로고
    • Hepsin promotes prostate cancer progression and metastasis
    • Klezovitch O, et al. (2004) Hepsin promotes prostate cancer progression and metastasis. Cancer Cell 6:185-195.
    • (2004) Cancer Cell , vol.6 , pp. 185-195
    • Klezovitch, O.1
  • 15
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • Zhang J, Thomas TZ, Kasper S, Matusik RJ (2000) A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology 141:4698-4710.
    • (2000) Endocrinology , vol.141 , pp. 4698-4710
    • Zhang, J.1    Thomas, T.Z.2    Kasper, S.3    Matusik, R.J.4
  • 16
    • 0023156939 scopus 로고
    • Prostatic intraepithelial neoplasia and early invasion in prostate cancer
    • Bostwick DG, Brawer MK (1987) Prostatic intraepithelial neoplasia and early invasion in prostate cancer. Cancer 59:788-794.
    • (1987) Cancer , vol.59 , pp. 788-794
    • Bostwick, D.G.1    Brawer, M.K.2
  • 18
    • 31944448885 scopus 로고    scopus 로고
    • Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
    • Wang S, et al. (2006) Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc Natl Acad Sci USA 103:1480-1485.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1480-1485
    • Wang, S.1
  • 19
    • 34547642493 scopus 로고    scopus 로고
    • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
    • Tomlins SA, et al. (2007) Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448:595-599.
    • (2007) Nature , vol.448 , pp. 595-599
    • Tomlins, S.A.1
  • 21
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 22
    • 0035936807 scopus 로고    scopus 로고
    • Hyperproliferation and defects in epithelial polarity upon conditional ablation of α-catenin in skin
    • Vasioukhin V, Bauer C, Degenstein L, Wise B, Fuchs E (2001) Hyperproliferation and defects in epithelial polarity upon conditional ablation of α-catenin in skin. Cell 104:605-617.
    • (2001) Cell , vol.104 , pp. 605-617
    • Vasioukhin, V.1    Bauer, C.2    Degenstein, L.3    Wise, B.4    Fuchs, E.5
  • 23
    • 0029202881 scopus 로고
    • Establishment and characterization of an immortalized but nontransformed human prostate epithelial cell line: BPH-1
    • Hayward SW, et al. (1995) Establishment and characterization of an immortalized but nontransformed human prostate epithelial cell line: BPH-1. In Vitro Cell Dev Biol 31:14-24.
    • (1995) In Vitro Cell Dev Biol , vol.31 , pp. 14-24
    • Hayward, S.W.1
  • 24
    • 25444529945 scopus 로고    scopus 로고
    • The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer
    • Miwa S, et al. (2005) The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer. Cancer Res 65:8818-8825.
    • (2005) Cancer Res , vol.65 , pp. 8818-8825
    • Miwa, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.