-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. & Weinberg, R. A. The hallmarks of cancer. Cell 100, 57-70 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0030715322
-
ECM cell surface proteolysis: Regulating cellular ecology
-
Werb, Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell 91, 439-442 (1997).
-
(1997)
Cell
, vol.91
, pp. 439-442
-
-
Werb, Z.1
-
4
-
-
15844420283
-
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3
-
Brooks, P. C. et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 85, 683-693 (1996). Localization of active MMP-2, secreted by stromal cells, to the cell surface of invasive cells by binding to αvβ3 integrin is necessary for invasive behaviour. Similar results relating to the importance of invasion, angiogenesis and TGF-β processing of tethering MMP-9 to the cell surface by binding to CD44 were reported in references 5 and 28.
-
(1996)
Cell
, vol.85
, pp. 683-693
-
-
Brooks, P.C.1
-
5
-
-
0032926177
-
Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion
-
Yu, Q. & Stamenkovic, I. Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev. 13, 35-48 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 35-48
-
-
Yu, Q.1
Stamenkovic, I.2
-
6
-
-
0036468005
-
CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling
-
Yu, W.-H., Woessner, J. F. Jr, McNeish, J. D. & Stamenkovic, I. CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling. Genes Dev. 16, 307-323 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 307-323
-
-
Yu, W.-H.1
Woessner J.F., Jr.2
McNeish, J.D.3
Stamenkovic, I.4
-
7
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht, M. D. & Werb, Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17, 463-516 (2001).
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
8
-
-
0028907318
-
Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease
-
Strongin, A. Y. et al. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J. Biol. Chem. 270, 5331-5338 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5331-5338
-
-
Strongin, A.Y.1
-
9
-
-
0035864376
-
MT1-MMP initiates activation of proMMP-2 and integrin αvβ3 promotes maturation of MMP-2 in breast carcinoma cells
-
Deryugina, E. I. et al. MT1-MMP initiates activation of proMMP-2 and integrin αvβ3 promotes maturation of MMP-2 in breast carcinoma cells. Exp. Cell Res. 263, 209-223 (2001).
-
(2001)
Exp. Cell Res.
, vol.263
, pp. 209-223
-
-
Deryugina, E.I.1
-
10
-
-
0035861560
-
Cellular activation of MMP-2 (Gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway
-
Morrison, C. J. et al. Cellular activation of MMP-2 (Gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway. J. Biol. Chem. 276, 47402-47410 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47402-47410
-
-
Morrison, C.J.1
-
11
-
-
0024495311
-
Human fibroblast collagenase-α-macrogrobulin interactions. Localization of cleavage sites in the bait regions of five mammalian α-macroglobulins
-
Sottrup-Jensen, L. & Birkedal-Hansen, H. Human fibroblast collagenase-α-macrogrobulin interactions. Localization of cleavage sites in the bait regions of five mammalian α-macroglobulins. J. Biol. Chem. 264, 393-401 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 393-401
-
-
Sottrup-Jensen, L.1
Birkedal-Hansen, H.2
-
12
-
-
0035896646
-
Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2
-
Yang, Z., Strickland, D. K. & Bornstein, P. Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2. J. Biol. Chem. 276, 8403-8408 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8403-8408
-
-
Yang, Z.1
Strickland, D.K.2
Bornstein, P.3
-
13
-
-
0034644748
-
Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity
-
Bein, K. & Simons, M. Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity. J. Biol. Chem. 275, 32167-32173 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32167-32173
-
-
Bein, K.1
Simons, M.2
-
14
-
-
0035940429
-
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
-
Rodriguez-Manzaneque, J. C. et al. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc. Natl Acad. Sci. USA 98, 12485-12490 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12485-12490
-
-
Rodriguez-Manzaneque, J.C.1
-
15
-
-
0033813281
-
The heparin binding 25 kDa fragment of thrombospondin-1 promotes angiogenesis and modulates gelatinase and TIMP-2 production in endothelial cells
-
Taraboletti, G. et al. The heparin binding 25 kDa fragment of thrombospondin-1 promotes angiogenesis and modulates gelatinase and TIMP-2 production in endothelial cells. FASEB J. 14, 1674-1676 (2000).
-
(2000)
FASEB J.
, vol.14
, pp. 1674-1676
-
-
Taraboletti, G.1
-
16
-
-
12444262485
-
-
(eds Clendeninn, N. J. & Appelt, K.) (Humana Press, Totowa, New Jersey)
-
Edwards, D. R. in Matrix Metalloproteinase inhibitors in Cancer Therapy (eds Clendeninn, N. J. & Appelt, K.) 67-84 (Humana Press, Totowa, New Jersey, 2001).
-
(2001)
Matrix Metalloproteinase inhibitors in Cancer Therapy
, pp. 67-84
-
-
Edwards, D.R.1
-
17
-
-
0034714202
-
TIMP-2 is required for efficient activation of proMMP-2 in vivo
-
Wang, Z., Juttermann, R. & Soloway, P. D. TIMP-2 is required for efficient activation of proMMP-2 in vivo. J. Biol. Chem. 275, 26411-26415 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26411-26415
-
-
Wang, Z.1
Juttermann, R.2
Soloway, P.D.3
-
18
-
-
0033955104
-
Post-translational proteolytic processing of procollagen C-terminal proteinase enhancer releases a metalloproteinase inhibitor
-
Mott, J. D. et al. Post-translational proteolytic processing of procollagen C-terminal proteinase enhancer releases a metalloproteinase inhibitor. J. Biol. Chem. 275, 1384-1390 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1384-1390
-
-
Mott, J.D.1
-
19
-
-
0031745767
-
Comparative analysis of the noncollagenous NC1 domain of type IV collagen: Identification of structural features important for assembly, function, and pathogenesis
-
Netzer, K. O., Suzuki, K., Itoh, Y., Hudson, B. G. & Khalifah, R. G. Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis. Protein Sci. 7, 1340-1351 (1998).
-
(1998)
Protein Sci.
, vol.7
, pp. 1340-1351
-
-
Netzer, K.O.1
Suzuki, K.2
Itoh, Y.3
Hudson, B.G.4
Khalifah, R.G.5
-
20
-
-
18244367390
-
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis
-
Oh, J. et al. The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 107, 789-800 (2001). Reports that deficiency of an MMP inhibitor, RECK, is embryonic lethal, due to a defect in vascular development. Also shows that the blood vessels in tumours that overexpress RECK have a reduced branching phenotype.
-
(2001)
Cell
, vol.107
, pp. 789-800
-
-
Oh, J.1
-
21
-
-
0032842777
-
Extracellular matrix remodelling and cellular differentiation
-
Streuli, C. Extracellular matrix remodelling and cellular differentiation. Curr. Opin. Cell. Biol. 11, 634-640 (1999).
-
(1999)
Curr. Opin. Cell. Biol.
, vol.11
, pp. 634-640
-
-
Streuli, C.1
-
22
-
-
0030798679
-
Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5
-
Giannelli, G., Falk-Marzillier, J., Schiraldi, O., Stetler-Stevenson, W. G. & Quaranta, V. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277, 225-228 (1997). Shows, together with reference 100, that cleavage of laminin-5 by MMPs triggers the migration of cells by unmasking a cryptic site that might act as a ligand for an unidentified cellular receptor.
-
(1997)
Science
, vol.277
, pp. 225-228
-
-
Giannelli, G.1
Falk-Marzillier, J.2
Schiraldi, O.3
Stetler-Stevenson, W.G.4
Quaranta, V.5
-
23
-
-
0035802109
-
Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo
-
Xu, J. et al. Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J. Cell Biol. 154, 1069-1080 (2001). Shows that a cryptic site within collagen type IV that is exposed following proteinase cleavage promotes angiogenesis and tumour growth, probably by Interacting with αvβ3 integrin. This cryptic site is detected in blood vessels from tumours but not normal tissue.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 1069-1080
-
-
Xu, J.1
-
24
-
-
0040776938
-
Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3
-
Manes, S. et al. Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3. J. Biol. Chem. 272, 25706-25712 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25706-25712
-
-
Manes, S.1
-
25
-
-
0040439972
-
The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells
-
Manes, S. et al. The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells. J. Biol. Chem. 274, 6935-6945 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6935-6945
-
-
Manes, S.1
-
26
-
-
0029876376
-
The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases
-
Whitelock, J. M., Murdoch, A. D., Iozzo, R. V. & Underwood, P. A. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases. J. Biol. Chem. 271, 10079-10086 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10079-10086
-
-
Whitelock, J.M.1
Murdoch, A.D.2
Iozzo, R.V.3
Underwood, P.A.4
-
27
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J. et al. An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284 (1998).
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
-
28
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
-
Yu, Q. & Stamenkovic, I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis. Genes Dev. 14, 163-176 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
29
-
-
0029959437
-
Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1
-
Levi, E. et al. Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1. Proc. Natl Acad. Sci. USA 93, 7069-7074 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7069-7074
-
-
Levi, E.1
-
30
-
-
0033559210
-
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
-
Codony-Servat, J., Albanell, J., Lopez-Talavera, J. C., Ambas, J. & Baselga, J. Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res. 59, 1196-1201 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 1196-1201
-
-
Codony-Servat, J.1
Albanell, J.2
Lopez-Talavera, J.C.3
Ambas, J.4
Baselga, J.5
-
31
-
-
0032493646
-
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin
-
Vecchi, M., Rudolph-Owen, L. A., Brown, C. L., Dempsey, P. J. & Carpenter, G. Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin. J. Biol. Chem. 273, 20589-20595 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20589-20595
-
-
Vecchi, M.1
Rudolph-Owen, L.A.2
Brown, C.L.3
Dempsey, P.J.4
Carpenter, G.5
-
32
-
-
0035074356
-
Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase
-
Nath, D., Williamson, N. J., Jarvis, R. & Murphy, G. Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase. J. Cell Sci. 114, 1213-1220 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1213-1220
-
-
Nath, D.1
Williamson, N.J.2
Jarvis, R.3
Murphy, G.4
-
33
-
-
0035147313
-
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
-
Noe, V. et al. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J. Cell Sci. 114, 111-118 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 111-118
-
-
Noe, V.1
-
34
-
-
0035947766
-
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration
-
Kajita, M. et al. Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J. Cell Biol. 153, 893-904 (2001). Reports that CD44 is shed by MMP-14 and that mutation of the cleavage site inhibits migration.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 893-904
-
-
Kajita, M.1
-
35
-
-
0012909831
-
Processing of integrin αV subunit by MT1-MMP stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of FAK
-
Nov 27; [epub ahead of print]
-
Deryugina, E. I., Ratnikov, B. I., Postnova, T. I., Rozanov, D. V & Strongin, A. Y. Processing of integrin αV subunit by MT1-MMP stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of FAK. J. Biol. Chem. 2001 Nov 27; [epub ahead of print].
-
(2001)
J. Biol. Chem.
-
-
Deryugina, E.I.1
Ratnikov, B.I.2
Postnova, T.I.3
Rozanov, D.V.4
Strongin, A.Y.5
-
36
-
-
0030293598
-
Matrix metalloproteinases and the development of cancer
-
Coussens, L. M. & Werb, Z. Matrix metalloproteinases and the development of cancer. Chem. Biol. 3, 895-904 (1996).
-
(1996)
Chem. Biol.
, vol.3
, pp. 895-904
-
-
Coussens, L.M.1
Werb, Z.2
-
37
-
-
0032559821
-
In vivo evidence that the stromeysin-3 metalloproteinase contnbutes in a paracrine manner to epithelial cell malignancy
-
Masson, R. et al. In vivo evidence that the stromeysin-3 metalloproteinase contnbutes in a paracrine manner to epithelial cell malignancy. J. Cell Biol. 140, 1535-1541 (1998).
-
(1998)
J. Cell Biol.
, vol.140
, pp. 1535-1541
-
-
Masson, R.1
-
38
-
-
0032031861
-
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
-
Itoh, T. et al. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res. 58, 1048-1051 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 1048-1051
-
-
Itoh, T.1
-
39
-
-
0032789885
-
Experimental metastasis is suppressed in MMP-9-deficient mice
-
Itoh, T. et al. Experimental metastasis is suppressed in MMP-9-deficient mice. Clin. Exp. Metastasis 17, 177-181 (1999).
-
(1999)
Clin. Exp. Metastasis
, vol.17
, pp. 177-181
-
-
Itoh, T.1
-
40
-
-
0033597726
-
The stromal proteinase MMP-3/stromelysin-1 promotes mammary carcinogenesis
-
Sternlicht, M. D. et al. The stromal proteinase MMP-3/ stromelysin-1 promotes mammary carcinogenesis. Cell 98, 137-146 (1999). Shows, together with reference 95, that active MMP-3 changes the phenotype of mammary epithelial cells to mesenchymal-like cells, and that the E-cadherin-β-catenin complex is involved in this regulation. Expression of an MMP, even when expressed only in the early stages of cancer development, is also sufficient to initiate tumour formation.
-
(1999)
Cell
, vol.98
, pp. 137-146
-
-
Sternlicht, M.D.1
-
41
-
-
0035110730
-
Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice
-
Ha, H. Y. et al. Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice. Cancer Res. 61, 984-990 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 984-990
-
-
Ha, H.Y.1
-
42
-
-
0034721666
-
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
-
Coussens, L. M., Tinkle, C. L., Hanahan, D. & Werb, Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 103, 481-490 (2000). In a transgenic mouse model of skin cancer, the reduced carcinogenesis in mice that are deficient for MMP9 can be completely restored by bone-marrow transplantation of MMP9-expressing cells. Tumours that arise in the absence of MMP9 are of a more advanced stage than those that arise in wild-type mice.
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
43
-
-
0035312892
-
Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance
-
Yang, W. et al. Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance. Cancer 91, 1277-1283 (2001).
-
(2001)
Cancer
, vol.91
, pp. 1277-1283
-
-
Yang, W.1
-
44
-
-
0031057805
-
Stromal expression of MMP-9 and urokinase receptor is inversely associated with liver metastasis and with infiltrating growth in human colorectal cancer: A novel approach from immune/inflammatory aspect
-
Takeha, S. et al. Stromal expression of MMP-9 and urokinase receptor is inversely associated with liver metastasis and with infiltrating growth in human colorectal cancer: a novel approach from immune/inflammatory aspect. Jpn. J. Cancer Res. 88, 72-81 (1997).
-
(1997)
Jpn. J. Cancer Res.
, vol.88
, pp. 72-81
-
-
Takeha, S.1
-
45
-
-
0035866816
-
Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery
-
Jiang, Y. et al. Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery. Cancer Res. 61, 2365-2370 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 2365-2370
-
-
Jiang, Y.1
-
46
-
-
0028132867
-
Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2)
-
Hayakawa, T., Yamashita, K., Ohuchi, E. & Shinagawa, A. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2) J. Cell Sci. 107, 2373-2379 (1994).
-
(1994)
J. Cell Sci.
, vol.107
, pp. 2373-2379
-
-
Hayakawa, T.1
Yamashita, K.2
Ohuchi, E.3
Shinagawa, A.4
-
47
-
-
0032484529
-
Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1 show enhanced vascular endothelial growth factor expression
-
Yoshiji, H. et al. Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1 show enhanced vascular endothelial growth factor expression. Int. J. Cancer 75, 81-87 (1998).
-
(1998)
Int. J. Cancer
, vol.75
, pp. 81-87
-
-
Yoshiji, H.1
-
48
-
-
0031763924
-
Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2
-
Gururajan, R. et al. Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2. Genome Res. 8, 929-939 (1998).
-
(1998)
Genome Res.
, vol.8
, pp. 929-939
-
-
Gururajan, R.1
-
49
-
-
0033152980
-
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors
-
Llano, E. et al. Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors. Cancer Res. 59, 2570-2576 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 2570-2576
-
-
Llano, E.1
-
50
-
-
0035141323
-
The PEA3 subfamily of Ets transcription factors synergizes with β-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors
-
Crawford, H. C. et al. The PEA3 subfamily of Ets transcription factors synergizes with β-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Mol. Cell Biol. 21, 1370-1383 (2001).
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 1370-1383
-
-
Crawford, H.C.1
-
51
-
-
0033597213
-
p53 down-regulates human matrix metalloproteinase-1 (collagenase-1) gene expression
-
Sun, Y. et al. p53 down-regulates human matrix metalloproteinase-1 (collagenase-1) gene expression. J. Biol. Chem. 274, 11535-11540 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11535-11540
-
-
Sun, Y.1
-
52
-
-
0034646643
-
Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13)
-
Sun, Y. et al. Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13). J. Biol. Chem. 275, 11327-11332 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11327-11332
-
-
Sun, Y.1
-
53
-
-
0028024812
-
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy
-
Polette, M. et al. Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy. Virchows Arch. 424, 641-645 (1994).
-
(1994)
Virchows Arch.
, vol.424
, pp. 641-645
-
-
Polette, M.1
-
54
-
-
0000282508
-
Correlation between expression of the matrix metalloproteinase-1 gene in ovanan cancers and an insertion/deletion polymorphism in its promoter region
-
Kanamori, Y. et al. Correlation between expression of the matrix metalloproteinase-1 gene in ovanan cancers and an insertion/deletion polymorphism in its promoter region. Cancer Res. 59, 4225-4227 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 4225-4227
-
-
Kanamori, Y.1
-
55
-
-
0035866375
-
Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism
-
Ye, S. et al. Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism. Cancer Res. 61, 1296-1298 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 1296-1298
-
-
Ye, S.1
-
56
-
-
0035503537
-
A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility
-
Zhu, Y., Spitz, M. R., Lei, L., Mills, G. B. & Wu, X. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility Cancer Res. 61, 7825-7829 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 7825-7829
-
-
Zhu, Y.1
Spitz, M.R.2
Lei, L.3
Mills, G.B.4
Wu, X.5
-
57
-
-
15844406034
-
Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression
-
Ye, S. et al. Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression. J. Biol. Chem. 271, 13055-13060 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13055-13060
-
-
Ye, S.1
-
58
-
-
0033635555
-
MMP1 and MMP3 polymorphisms in promoter regions and cancer
-
Biondi, M. L. et al. MMP1 and MMP3 polymorphisms in promoter regions and cancer. Clin. Chem. 46, 2023-2024 (2000).
-
(2000)
Clin. Chem.
, vol.46
, pp. 2023-2024
-
-
Biondi, M.L.1
-
59
-
-
0000391746
-
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
-
Bergers, G. et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nature Cell Biol. 2, 737-744 (2000). M MP-9 controls tumour angiogenesis by increasing the bioavailability of VEGF, and is expressed by stromal cells but not by cancer cells. MMP-2 also influences tumour growth but not angiogenesis. Invasion is not affected by MMP-2 or MMP-9.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 737-744
-
-
Bergers, G.1
-
60
-
-
0028171268
-
The αvβ6 integrin promotes proliferation of colon carcinoma cells through a unique region of the β 6 cytoplasmic domain
-
Agrez, M., Chen, A., Cone, R. I., Pytela, R. & Sheppard, D. The αvβ6 integrin promotes proliferation of colon carcinoma cells through a unique region of the β6 cytoplasmic domain. J. Cell Biol. 127, 547-556 (1994).
-
(1994)
J. Cell Biol.
, vol.127
, pp. 547-556
-
-
Agrez, M.1
Chen, A.2
Cone, R.I.3
Pytela, R.4
Sheppard, D.5
-
61
-
-
0034785348
-
TGF-β signaling in tumor suppression and cancer progression
-
Derynck, R., Akhurst, R. J. & Balmain, A. TGF-β signaling in tumor suppression and cancer progression. Nature Genet. 29, 117-129 (2001).
-
(2001)
Nature Genet.
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
62
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed, J. C. Mechanisms of apoptosis avoidance in cancer. Curr. Opin. Oncol. 11, 68-75 (1999).
-
(1999)
Curr. Opin. Oncol.
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
63
-
-
0030454231
-
Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene
-
Alexander, C. M., Howard, E. W., Bissell, M. J. & Werb, Z. Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene. J. Cell Biol. 135, 1669-1677 (1996).
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1669-1677
-
-
Alexander, C.M.1
Howard, E.W.2
Bissell, M.J.3
Werb, Z.4
-
64
-
-
0028916958
-
Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis
-
Witty, J. P., Lempka, T., Coffey, R. J. Jr & Matrisian, L. M. Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer Res. 55, 1401-1406 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 1401-1406
-
-
Witty, J.P.1
Lempka, T.2
Coffey R.J., Jr.3
Matrisian, L.M.4
-
65
-
-
0028302990
-
Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression
-
Sympson, C. J. et al. Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. J. Cell Biol. 125, 681-693 (1994).
-
(1994)
J. Cell Biol.
, vol.125
, pp. 681-693
-
-
Sympson, C.J.1
-
66
-
-
0033576645
-
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
-
Powell, W. C., Fingleton, B., Wilson, C. L., Boothby, M. & Matrisian, L. M. The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis. Curr. Biol. 9, 1441-1447 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 1441-1447
-
-
Powell, W.C.1
Fingleton, B.2
Wilson, C.L.3
Boothby, M.4
Matrisian, L.M.5
-
67
-
-
0035863471
-
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity
-
Mitsiades, N., Yu, W.-H., Poulaki, V., Tsokos, M. & Stamenkovic, I. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res. 61, 577-581 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 577-581
-
-
Mitsiades, N.1
Yu, W.-H.2
Poulaki, V.3
Tsokos, M.4
Stamenkovic, I.5
-
68
-
-
0034904145
-
Stromelysin-3 suppresses tumor cell apoptosis in a murine model
-
Wu, E. et al. Stromelysin-3 suppresses tumor cell apoptosis in a murine model. J. Cell Biochem. 82, 549-555 (2001).
-
(2001)
J. Cell Biochem.
, vol.82
, pp. 549-555
-
-
Wu, E.1
-
69
-
-
0035266386
-
High cancer cell death in syngeneic tumors developed in host mice deficient for the stromelysin-3 matrix metalloproteinase
-
Boulay, A. et al. High cancer cell death in syngeneic tumors developed in host mice deficient for the stromelysin-3 matrix metalloproteinase. Cancer Res. 61, 2189-2193 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 2189-2193
-
-
Boulay, A.1
-
70
-
-
0034693756
-
The contradictions of the insulin-like growth factor 1 receptor
-
Baserga, R. The contradictions of the insulin-like growth factor 1 receptor. Oncogene 19, 5574-5581 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 5574-5581
-
-
Baserga, R.1
-
71
-
-
0034605046
-
Requirement for matrix metalloproteinase stromelysin-3 in cell migration and apoptosis during tissue remodeling in Xenopus laevis
-
Ishizuya-Oka, A. et al. Requirement for matrix metalloproteinase stromelysin-3 in cell migration and apoptosis during tissue remodeling in Xenopus laevis. J. Cell Biol. 150, 1177-1188 (2000).
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1177-1188
-
-
Ishizuya-Oka, A.1
-
72
-
-
0346963598
-
MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
-
Vu, T. H. et al. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93, 411-422 (1998).
-
(1998)
Cell
, vol.93
, pp. 411-422
-
-
Vu, T.H.1
-
73
-
-
0031867833
-
Cleavage of β-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: Evidence for a role for caspases and metalloproteinases
-
Herren, B., Levkau, B., Raines, E. W. & Ross, R. Cleavage of β-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol. Biol. Cell 9, 1589-1601 (1998).
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 1589-1601
-
-
Herren, B.1
Levkau, B.2
Raines, E.W.3
Ross, R.4
-
74
-
-
0035124602
-
PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling charactenstics
-
Ilan, N., Mohsenin, A., Cheung, L. & Madri, J. A. PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling charactenstics. FASEB J. 15, 362-372 (2001).
-
(2001)
FASEB J.
, vol.15
, pp. 362-372
-
-
Ilan, N.1
Mohsenin, A.2
Cheung, L.3
Madri, J.A.4
-
75
-
-
0035895927
-
Cleavage and shedding of E-cadherin after induction of apoptosis
-
Steinhusen, U. et al. Cleavage and shedding of E-cadherin after induction of apoptosis. J. Biol. Chem. 276, 4972-4980 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4972-4980
-
-
Steinhusen, U.1
-
76
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan, D. & Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 353-364 (1996).
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
77
-
-
0032985639
-
Transgenic TMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis
-
Martin, D. C. et al. Transgenic TMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis Lab. Invest. 79, 225-234 (1999).
-
(1999)
Lab. Invest.
, vol.79
, pp. 225-234
-
-
Martin, D.C.1
-
78
-
-
0035937312
-
AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice
-
Li, H. et al. AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice. Hum. Gene Ther. 12, 515-526 (2001).
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 515-526
-
-
Li, H.1
-
79
-
-
0032710567
-
BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity
-
Gatto, C. et al. BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity. Clin. Cancer Res. 5, 3603-3607 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3603-3607
-
-
Gatto, C.1
-
80
-
-
0035871750
-
Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen
-
Seandel, M., Noack-Kunnmann, K., Zhu, D., Aimes, R. T. & Quigley J. P. Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen. Blood 97, 2323-2332 (2001).
-
(2001)
Blood
, vol.97
, pp. 2323-2332
-
-
Seandel, M.1
Noack-Kunnmann, K.2
Zhu, D.3
Aimes, R.T.4
Quigley, J.P.5
-
81
-
-
0030877993
-
The matrix metallopreteinase RASI-1 is expressed in synovial blood vessels of a rheumatoid arthritis patient
-
Kolb, C., Mauch, S., Peter, H. H., Krawinkel, U. & Sedlacek, R. The matrix metallopreteinase RASI-1 is expressed in synovial blood vessels of a rheumatoid arthritis patient. Immunol. Lett. 57, 83-88 (1997).
-
(1997)
Immunol. Lett.
, vol.57
, pp. 83-88
-
-
Kolb, C.1
Mauch, S.2
Peter, H.H.3
Krawinkel, U.4
Sedlacek, R.5
-
82
-
-
0034635995
-
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
-
Fang, J. et al. Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model. Proc. Natl Acad. Sci. USA 97, 3884-3889 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3884-3889
-
-
Fang, J.1
-
83
-
-
0035813126
-
Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling
-
Galvez, B. G., Matias-Roman, S., Albar, J. P., Sanchez-Madrid, F. & Arroyo, A. G. Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling. J. Biol. Chem. 276, 37491-37500 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37491-37500
-
-
Galvez, B.G.1
Matias-Roman, S.2
Albar, J.P.3
Sanchez-Madrid, F.4
Arroyo, A.G.5
-
84
-
-
0032582686
-
Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins
-
Hiraoka, N., Allen, E., Apel, I. J., Gyetko, M. R., & Weiss, S. J. Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell 95, 365-377 (1998).
-
(1998)
Cell
, vol.95
, pp. 365-377
-
-
Hiraoka, N.1
Allen, E.2
Apel, I.J.3
Gyetko, M.R.4
Weiss, S.J.5
-
85
-
-
0034635966
-
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
-
Zhou, Z. et al. Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc. Natl Acad. Sci. USA 97, 4052-4057 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4052-4057
-
-
Zhou, Z.1
-
86
-
-
0030998660
-
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma
-
Dong, Z., Kumar, R., Yang, X. & Fidler I. J. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell 88, 801-810 (1997). The first paper to show that MMP cleavage can produce anti-angiogenic fragments of ECM components.
-
(1997)
Cell
, vol.88
, pp. 801-810
-
-
Dong, Z.1
Kumar, R.2
Yang, X.3
Fidler, I.J.4
-
87
-
-
0032534596
-
Matrix metalloproteinases generate angiostatin: Effects on neovascularization
-
Cornelius, L. A. et al. Matrix metalloproteinases generate angiostatin: effects on neovascularization. J. Immunol. 161, 6845-6852 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 6845-6852
-
-
Cornelius, L.A.1
-
88
-
-
17144437129
-
Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis
-
Gorrin-Rivas, M. J. et al. Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis. Clin. Cancer Res. 6, 1647-1654 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1647-1654
-
-
Gorrin-Rivas, M.J.1
-
89
-
-
0034672644
-
Generation and degradation of human endostatin proteins by various proteinases
-
Ferreras, M., Felbor, U., Lenhard, T., Olsen, B. R. & Delaisse, J. Generation and degradation of human endostatin proteins by various proteinases. FEBS Lett. 486, 247-251 (2000).
-
(2000)
FEBS Lett.
, vol.486
, pp. 247-251
-
-
Ferreras, M.1
Felbor, U.2
Lenhard, T.3
Olsen, B.R.4
Delaisse, J.5
-
90
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
O'Reilly, M. S. et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328 (1994).
-
(1994)
Cell
, vol.79
, pp. 315-328
-
-
O'Reilly, M.S.1
-
91
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly, M. S. et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88, 277-285 (1997).
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
-
92
-
-
0034307327
-
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase
-
Kim, Y. M. et al. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res. 60, 5410-5413 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 5410-5413
-
-
Kim, Y.M.1
-
93
-
-
0035874516
-
Proteolysis of the urokinase-type plasminogen activator receptor by metalloproteinase-12: Implication for angiogenesis in fibrin matrices
-
Koolwijk, P. et al. Proteolysis of the urokinase-type plasminogen activator receptor by metalloproteinase-12: implication for angiogenesis in fibrin matrices. Blood 97, 3123-3131 (2001).
-
(2001)
Blood
, vol.97
, pp. 3123-3131
-
-
Koolwijk, P.1
-
94
-
-
0032101072
-
Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells
-
Ahonen, M., Baker, A. H. & Kahad, V. M. Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells. Cancer Res. 58, 2310-2315 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 2310-2315
-
-
Ahonen, M.1
Baker, A.H.2
Kahad, V.M.3
-
95
-
-
0031426654
-
Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells
-
Lochter, A. et al. Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J. Cell Biol. 139, 1861-1872 (1997).
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1861-1872
-
-
Lochter, A.1
-
96
-
-
0033601769
-
Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter
-
Belien, A. T., Paganetti, P. A. & Schwab, M. E. Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter. J. Cell Biol. 144, 373-384 (1999).
-
(1999)
J. Cell Biol.
, vol.144
, pp. 373-384
-
-
Belien, A.T.1
Paganetti, P.A.2
Schwab, M.E.3
-
97
-
-
0030827411
-
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2
-
Deryugina, E. I., Luo, G. X., Reisfeld, R. A., Bourdon, M. A. & Strongin, A. Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2. Anticancer Res. 17, 3201-3210 (1997).
-
(1997)
Anticancer Res.
, vol.17
, pp. 3201-3210
-
-
Deryugina, E.I.1
Luo, G.X.2
Reisfeld, R.A.3
Bourdon, M.A.4
Strongin, A.5
-
98
-
-
0037137876
-
Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells
-
Ala-Aho, R., Johansson, N., Baker, A. H. & Kahan, V. M. Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells. Int. J. Cancer 97, 283-289 (2002).
-
(2002)
Int. J. Cancer
, vol.97
, pp. 283-289
-
-
Ala-Aho, R.1
Johansson, N.2
Baker, A.H.3
Kahan, V.M.4
-
99
-
-
0029824947
-
Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system
-
Hua, J. & Muschel, R. J. Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system. Cancer Res. 56, 5279-5284 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 5279-5284
-
-
Hua, J.1
Muschel, R.J.2
-
100
-
-
0034614939
-
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
-
Koshikawa, N., Giannelli, G., Cirulli, V., Miyazaki, K. & Quaranta, V. Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J. Cell Biol. 148, 615-624 (2000).
-
(2000)
J. Cell Biol.
, vol.148
, pp. 615-624
-
-
Koshikawa, N.1
Giannelli, G.2
Cirulli, V.3
Miyazaki, K.4
Quaranta, V.5
-
101
-
-
0030460634
-
Epithelial-mesenchymal transitions in cancer progression
-
Birchmeier, C., Birchmeier, W. & Brand-Saben, B. Epithelial-mesenchymal transitions in cancer progression. Acta Anat. (Basel.) 156, 217-226 (1996).
-
(1996)
Acta Anat. (Basel.)
, vol.156
, pp. 217-226
-
-
Birchmeier, C.1
Birchmeier, W.2
Brand-Saben, B.3
-
102
-
-
0030791315
-
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
-
Nakahara, H. et al. Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc. Natl Acad. Sci. USA 94, 7959-7964 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7959-7964
-
-
Nakahara, H.1
-
103
-
-
0031808063
-
CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells
-
Bourguignon, L. Y. et al. CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells. J. Cell Physiol. 176, 206-215 (1998).
-
(1998)
J. Cell Physiol.
, vol.176
, pp. 206-215
-
-
Bourguignon, L.Y.1
-
104
-
-
0032493871
-
Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
-
Kim, J., Yu, W., Kovalski, K. & Ossowski, L. Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell 94, 353-362 (1998).
-
(1998)
Cell
, vol.94
, pp. 353-362
-
-
Kim, J.1
Yu, W.2
Kovalski, K.3
Ossowski, L.4
-
105
-
-
0029753004
-
Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay
-
Tsunezuka, Y. et al. Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay. Cancer Res. 56, 5678-5683 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 5678-5683
-
-
Tsunezuka, Y.1
-
106
-
-
0028129494
-
Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth
-
Koop, S. et al. Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Res. 54, 4791-4797 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 4791-4797
-
-
Koop, S.1
-
107
-
-
1842331535
-
Altered tumor growth and metastasis of a T-cell lymphoma in Timp-1 transgenic mice
-
Krüger, A., Fata, J. E. & Khokha, R. Altered tumor growth and metastasis of a T-cell lymphoma in Timp-1 transgenic mice. Blood 90, 1993-2000 (1997).
-
(1997)
Blood
, vol.90
, pp. 1993-2000
-
-
Krüger, A.1
Fata, J.E.2
Khokha, R.3
-
108
-
-
0032493066
-
Host TIMP-1 overexpression confers resistance to experimental brain metastasis of a fibrosarcoma cell line
-
Krüger, A. et al. Host TIMP-1 overexpression confers resistance to experimental brain metastasis of a fibrosarcoma cell line. Oncogene 16, 2419-2423 (1998).
-
(1998)
Oncogene
, vol.16
, pp. 2419-2423
-
-
Krüger, A.1
-
109
-
-
0030471877
-
Targeted mutagenesis of Timp-1 reveals that lung tumor invasion is influenced by Timp-1 genotype of the tumor but not by that of the host
-
Soloway, P. D., Alexander, C. M., Werb, Z. & Jaenisch, R. Targeted mutagenesis of Timp-1 reveals that lung tumor invasion is influenced by Timp-1 genotype of the tumor but not by that of the host. Oncogene 13, 2307-2314 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 2307-2314
-
-
Soloway, P.D.1
Alexander, C.M.2
Werb, Z.3
Jaenisch, R.4
-
110
-
-
0035911230
-
Inflammatory cells and cancer: Think different!
-
Coussens, L. M. & Werb, Z. Inflammatory cells and cancer: think different! J. Exp. Med. 193, F23-F26 (2001).
-
(2001)
J. Exp. Med.
, vol.193
-
-
Coussens, L.M.1
Werb, Z.2
-
111
-
-
0035137707
-
A novel role of metalloproteinase in cancer-mediated immunosuppression
-
Sheu, B.-C. et al. A novel role of metalloproteinase in cancer-mediated immunosuppression. Cancer Res. 61, 237-242 (2001). Shows that MMPs can suppress the proliferation of activated T lymphocytes by shedding the interleukin-2 receptor-α from their surface.
-
(2001)
Cancer Res.
, vol.61
, pp. 237-242
-
-
Sheu, B.-C.1
-
112
-
-
0034770605
-
Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
-
Gorelik, L. & Flavell, R. A. Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells. Nature Med. 7, 1118-1122 (2001).
-
(2001)
Nature Med.
, vol.7
, pp. 1118-1122
-
-
Gorelik, L.1
Flavell, R.A.2
-
113
-
-
0032912952
-
Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of α1-proteinase inhibitor generated by matrix metalloproteinases: A possible modulatory role in natural killer cytotoxicity
-
Kataoka, H. et al. Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of α1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity. Am. J. Pathol. 154, 457-468 (1999).
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 457-468
-
-
Kataoka, H.1
-
114
-
-
0035471778
-
Gelatinase B: A tuner and amplifier of immune functions
-
Opdenakker, G., Van den Steen, P. E. & Van Damme, J. Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol. 22, 571-579 (2001).
-
(2001)
Trends Immunol.
, vol.22
, pp. 571-579
-
-
Opdenakker, G.1
Van den Steen, P.E.2
Van Damme, J.3
-
115
-
-
0034682885
-
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3
-
McQuibban, G. A. et al. Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science 289, 1202-1206 (2000). MMPs regulate the inflammatory response by cleaving CCL7 - a chemokine that is involved in leukocyte recruitment - thereby converting it to an antagonist of its receptors.
-
(2000)
Science
, vol.289
, pp. 1202-1206
-
-
McQuibban, G.A.1
-
116
-
-
0035941359
-
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
-
McQuibban, G. A. et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1 J. Biol. Chem. 276, 43503-43508 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43503-43508
-
-
McQuibban, G.A.1
-
117
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Müller, A. et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56 (2001).
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Müller, A.1
-
118
-
-
0034945477
-
Inhibition of peritoneal dissemination in human gastric cancer by MMP-7-specific antisense oligonucleotide
-
Yonemura, Y. et al. Inhibition of peritoneal dissemination in human gastric cancer by MMP-7-specific antisense oligonucleotide. J. Exp. Clin. Cancer Res. 20, 205-212 (2001).
-
(2001)
J. Exp. Clin. Cancer Res.
, vol.20
, pp. 205-212
-
-
Yonemura, Y.1
-
119
-
-
0034671911
-
Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion
-
Kondraganti, S. et al. Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion. Cancer Res. 60, 6851-6855 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 6851-6855
-
-
Kondraganti, S.1
-
120
-
-
0034104525
-
Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: Role as anticancer agents
-
Noonberg, S. B. & Benz, C. C. Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: role as anticancer agents. Drugs 59, 753-767 (2000).
-
(2000)
Drugs
, vol.59
, pp. 753-767
-
-
Noonberg, S.B.1
Benz, C.C.2
-
121
-
-
0032787282
-
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone
-
Elkin, M. et al. Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone. Clin. Cancer Res. 5, 1982-1988 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1982-1988
-
-
Elkin, M.1
-
122
-
-
0035793037
-
Disruption of matrix metalloproteinase 2 binding to integrin αvβ3 by an organic molecule inhibits angiogenesis and tumor growth in vivo
-
Silletti, S., Kessler, T., Goldberg, J., Boger, D. L. & Cheresh, D. A. Disruption of matrix metalloproteinase 2 binding to integrin αvβ3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. Proc. Natl Acad. Sci. USA 98, 119-124 (2001). Characterizes a compound that inhibits tumour growth by specifically disrupting the protein-protein interaction between MMP-2 and αvβ3 integrin, without any effects on MMP-2 activity in general.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 119-124
-
-
Silletti, S.1
Kessler, T.2
Goldberg, J.3
Boger, D.L.4
Cheresh, D.A.5
-
123
-
-
0034326255
-
Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin
-
Liu, S., Netzel-Arnett, S., Birkedal-Hansen, H. & Leppla, S. H. Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin. Cancer Res. 60, 6061-6067 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 6061-6067
-
-
Liu, S.1
Netzel-Arnett, S.2
Birkedal-Hansen, H.3
Leppla, S.H.4
-
124
-
-
0035913171
-
Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA
-
Celiker, M. Y. et al. Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA. Oncogene 20, 4337-4343 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 4337-4343
-
-
Celiker, M.Y.1
-
125
-
-
0034667462
-
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue
-
Brand, K. et al. Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue. Cancer Res. 60, 5723-5730 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 5723-5730
-
-
Brand, K.1
-
126
-
-
0032842567
-
Tumor targeting with a selective gelatinase inhibitor
-
Koivunen, E. et al. Tumor targeting with a selective gelatinase inhibitor. Nature Biotechnol. 17, 768-774 (1999). Characterizes a peptide inhibitor that specifically inhibits the gelatin-binding MMPs, but not other MMPs.
-
(1999)
Nature Biotechnol.
, vol.17
, pp. 768-774
-
-
Koivunen, E.1
-
127
-
-
0035424135
-
Marimastat as first-line therapy for patients with unresectable pancreatic cancer: A randomized trial
-
Bramhall, S. R., Rosemurgy, A., Brown, P. D., Bowry, C. & Buckels, J. A. Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial. J. Clin. Oncol. 19, 3447-3455 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 3447-3455
-
-
Bramhall, S.R.1
Rosemurgy, A.2
Brown, P.D.3
Bowry, C.4
Buckels, J.A.5
-
128
-
-
0034489694
-
A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours
-
Hirte, H. et al. A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours. Ann. Oncol. 11, 1579-1584 (2000).
-
(2000)
Ann. Oncol.
, vol.11
, pp. 1579-1584
-
-
Hirte, H.1
-
130
-
-
0035819527
-
Development of matrix metalloproteinase inhibitors in cancer therapy
-
Hidalgo, M. & Eckhardt, S. G. Development of matrix metalloproteinase inhibitors in cancer therapy. J. Natl Cancer Inst. 93, 178-193 (2001).
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 178-193
-
-
Hidalgo, M.1
Eckhardt, S.G.2
-
131
-
-
0034214362
-
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
-
Boissier, S. et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res. 60, 2949-2954 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 2949-2954
-
-
Boissier, S.1
-
132
-
-
0035060804
-
Matrix proteinase inhibition by AE·941, a multifunctional antiangiogenic compound
-
Gingras, D. et al. Matrix proteinase inhibition by AE·941, a multifunctional antiangiogenic compound. Anticancer Res. 21, 145-155 (2001).
-
(2001)
Anticancer Res.
, vol.21
, pp. 145-155
-
-
Gingras, D.1
-
133
-
-
0035207897
-
Neovastat, a naturally occurring multifunctional antiangiogenic drug, in phase III clinical trials
-
Falardeau, P., Champagne, P., Poyet, P., Hariton, C. & Dupont, E. Neovastat, a naturally occurring multifunctional antiangiogenic drug, in phase III clinical trials. Semin. Oncol. 28, 620-625 (2001).
-
(2001)
Semin. Oncol.
, vol.28
, pp. 620-625
-
-
Falardeau, P.1
Champagne, P.2
Poyet, P.3
Hariton, C.4
Dupont, E.5
-
134
-
-
0032696536
-
Tumor invasion: Molecular shears blunted by green tea
-
Garbisa, S. et al. Tumor invasion: molecular shears blunted by green tea. Nature Med. 5, 1216 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 1216
-
-
Garbisa, S.1
-
135
-
-
0025998557
-
Aspirin use and reduced risk of fatal colon cancer
-
Thun, M. J., Namboodiri, M. M. & Heath, C. W. Jr. Aspirin use and reduced risk of fatal colon cancer. N. Engl. J. Med. 325, 1593-1596 (1991).
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1593-1596
-
-
Thun, M.J.1
Namboodiri, M.M.2
Heath C.W., Jr.3
-
136
-
-
0034805565
-
Aspirin inhibits matrix metalloproteinase-2 activity increases E-cadherin production, and inhibits in vitro invasion of tumor cells
-
Jiang, M. C., Liao, C. F. & Lee, P. H. Aspirin inhibits matrix metalloproteinase-2 activity increases E-cadherin production, and inhibits in vitro invasion of tumor cells. Biochem. Biophys. Res. Commun. 282, 671-677 (2001).
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 671-677
-
-
Jiang, M.C.1
Liao, C.F.2
Lee, P.H.3
-
137
-
-
0033617532
-
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
-
Bergers, G., Javaherian, K., Lo, K. M., Folkman, J. & Hanahan, D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 284, 808-812 (1999).
-
(1999)
Science
, vol.284
, pp. 808-812
-
-
Bergers, G.1
Javaherian, K.2
Lo, K.M.3
Folkman, J.4
Hanahan, D.5
-
138
-
-
0029934985
-
Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)
-
Eccles, S. A. et al. Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94). Cancer Res. 56, 2815-2822 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 2815-2822
-
-
Eccles, S.A.1
-
139
-
-
0036007414
-
Shedding light on sheddases: Role in growth and development
-
Kheradmand, F. & Werb, Z. Shedding light on sheddases: role in growth and development. Bioessays 24, 8-12 (2002).
-
(2002)
Bioessays
, vol.24
, pp. 8-12
-
-
Kheradmand, F.1
Werb, Z.2
-
140
-
-
0035129903
-
ADAMTS: A novel family of extracellular matrix proteases
-
Tang, B. L. ADAMTS: a novel family of extracellular matrix proteases. Int. J. Biochem. Cell Biol. 33, 33-44 (2001).
-
(2001)
Int. J. Biochem. Cell Biol.
, vol.33
, pp. 33-44
-
-
Tang, B.L.1
-
141
-
-
0003987013
-
-
(eds Kreis, T. & Vale, R.) (Oxford Univ. Press, Oxford, UK
-
Olsen, B. R. & Ninomiya, Y. in Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins (eds Kreis, T. & Vale, R.) 380-408 (Oxford Univ. Press, Oxford, UK, 1999).
-
(1999)
Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins
, pp. 380-408
-
-
Olsen, B.R.1
Ninomiya, Y.2
-
142
-
-
0037016498
-
Tumstatin, an endothelial cell-specific inhibitor of protein synthesis
-
Maeshima, Y. et al. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science 295, 140-143 (2002).
-
(2002)
Science
, vol.295
, pp. 140-143
-
-
Maeshima, Y.1
-
143
-
-
0003987013
-
-
(eds Kreis, T. & Vale, R.) (Oxford Univ. Press, Oxford, UK)
-
Sasaki, T. & Timpl, R. in Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins (eds Kreis, T. & Vale, R.) 434-443 (Oxford Univ. Press, Oxford, UK, 1999).
-
(1999)
Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins
, pp. 434-443
-
-
Sasaki, T.1
Timpl, R.2
-
144
-
-
0003987013
-
-
(eds Kreis, T. & Vale, R.) (Oxford Univ. Press, Oxford, UK)
-
Hynes, R. in Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins (eds Kreis, T. & Vale, R.) 422-425 (Oxford Univ. Press, Oxford, UK, 1999).
-
(1999)
Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins
, pp. 422-425
-
-
Hynes, R.1
-
145
-
-
0034715896
-
Insights into extracellular matrix functions from mutant mouse models
-
Gustafsson, E. & Fassler, R. Insights into extracellular matrix functions from mutant mouse models. Exp. Cell Res. 261, 52-68 (2000).
-
(2000)
Exp. Cell Res.
, vol.261
, pp. 52-68
-
-
Gustafsson, E.1
Fassler, R.2
-
146
-
-
0003987013
-
-
(eds Kreis, T. & Vale, R.) (Oxford Univ. Press, Oxford, UK)
-
Lander, A. D. in Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins (eds Kreis, T. & Vale, R.) 351-356 (Oxford Univ. Press, Oxford, UK, 1999).
-
(1999)
Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins
, pp. 351-356
-
-
Lander, A.D.1
-
147
-
-
0030581637
-
Identification of MMP-18, a putative novel human matrix metalloproteinase
-
Cossins, J., Dudgeon, T. J., Catlin, G., Gearing, A. J. & Clements, J. M. Identification of MMP-18, a putative novel human matrix metalloproteinase. Biochem. Biophys. Res. Commun. 228, 494-498 (1996).
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.228
, pp. 494-498
-
-
Cossins, J.1
Dudgeon, T.J.2
Catlin, G.3
Gearing, A.J.4
Clements, J.M.5
-
148
-
-
0035875151
-
Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin
-
Marchenko, G. N. et al. Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin. Biochem. J. 356, 705-718 (2001).
-
(2001)
Biochem. J.
, vol.356
, pp. 705-718
-
-
Marchenko, G.N.1
-
149
-
-
0034721850
-
Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a single cleavage for both secretion and activation
-
Pei, D., Kang, T. & Qi, H. Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a single cleavage for both secretion and activation. J. Biol. Chem. 275, 33988-33997 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33988-33997
-
-
Pei, D.1
Kang, T.2
Qi, H.3
-
150
-
-
17744381545
-
Cloning and characterization of a rat ortholog of MMP-23 (matrix metalloproteinase-23), a unique type of membrane-anchored matrix metalloproteinase and conditioned switching of its expression during the ovarian follicular development
-
Ohnishi, J. et al. Cloning and characterization of a rat ortholog of MMP-23 (matrix metalloproteinase-23), a unique type of membrane-anchored matrix metalloproteinase and conditioned switching of its expression during the ovarian follicular development. Mol. Endocrinol. 15, 747-764 (2001).
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 747-764
-
-
Ohnishi, J.1
-
151
-
-
0029122808
-
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis
-
D'Armiento, J. et al. Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis. Mol. Cell Biol. 15, 5732-5739 (1995).
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 5732-5739
-
-
D'Armiento, J.1
-
152
-
-
0033780265
-
Collagenase induction promotes mouse tumorigenesis by two independent pathways
-
Colandrea, T. D., D'Armiento, J., Kesan, K. V. & Chada, K. K. Collagenase induction promotes mouse tumorigenesis by two independent pathways. Mol. Carcinog. 29, 8-16 (2000).
-
(2000)
Mol. Carcinog.
, vol.29
, pp. 8-16
-
-
Colandrea, T.D.1
D'Armiento, J.2
Kesan, K.V.3
Chada, K.K.4
-
153
-
-
0033592538
-
Cancer biology: Extracellular proteinases in malignancy
-
Matrisian, L. M. Cancer biology: extracellular proteinases in malignancy. Curr. Biol. 9, R776-R778 (1999).
-
(1999)
Curr. Biol.
, vol.9
-
-
Matrisian, L.M.1
-
154
-
-
0032403129
-
The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis
-
Rudolph-Owen, L. A., Chan, R., Muller, W. J. & Matrisian, L. M. The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Cancer Res. 58, 5500-5506 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 5500-5506
-
-
Rudolph-Owen, L.A.1
Chan, R.2
Muller, W.J.3
Matrisian, L.M.4
-
155
-
-
0031036359
-
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin
-
Wilson, C. L., Heppner, K. J., Labosky, P. A., Hogan, B. L. & Matrisian, L. M. Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc. Natl Acad. Sci. USA 94, 1402-1407 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1402-1407
-
-
Wilson, C.L.1
Heppner, K.J.2
Labosky, P.A.3
Hogan, B.L.4
Matrisian, L.M.5
-
156
-
-
0029836160
-
Inhibition of SV40 T antigen-induced hepatocellular carcinoma in T1MP-1 transgenic mice
-
Martin, D. C., Rüther, U., Sanchez-Sweatman, O. H., Orr, F. W. & Khokha, R. Inhibition of SV40 T antigen-induced hepatocellular carcinoma in T1MP-1 transgenic mice. Oncogene 13, 569-576 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 569-576
-
-
Martin, D.C.1
Rüther, U.2
Sanchez-Sweatman, O.H.3
Orr, F.W.4
Khokha, R.5
-
157
-
-
0032816215
-
The effects of sustained elevated levels of circulating tissue inhibitor of metalloproteinases-1 on the development of breast cancer in mice
-
Buck, T. B., Yoshiji, H., Harris, S. R., Bunce, O. R. & Thorgeirsson, U. P. The effects of sustained elevated levels of circulating tissue inhibitor of metalloproteinases-1 on the development of breast cancer in mice. Ann. NY Acad. Sci. 878, 732-735 (1999).
-
(1999)
Ann. NY Acad. Sci.
, vol.878
, pp. 732-735
-
-
Buck, T.B.1
Yoshiji, H.2
Harris, S.R.3
Bunce, O.R.4
Thorgeirsson, U.P.5
-
158
-
-
0000278421
-
Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis
-
Goss, K. J., Brown, P. D. & Matrisian, L. M. Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis. Int. J. Cancer 78, 629-635 (1998).
-
(1998)
Int. J. Cancer
, vol.78
, pp. 629-635
-
-
Goss, K.J.1
Brown, P.D.2
Matrisian, L.M.3
-
159
-
-
0142206478
-
Status of matrix metalloproteinase inhibitors as anti-cancer therapeutics
-
in the press
-
Coussens, L. M., Fingleton, B. & Matrisian, L. M. Status of matrix metalloproteinase inhibitors as anti-cancer therapeutics. Science (in the press)
-
Science
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
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