메뉴 건너뛰기




Volumn 11, Issue 3, 2011, Pages 307-324

Targeting proteasomes with naturally occurring compounds in cancer treatment

Author keywords

Apoptosis; Cancer; Polyphenols; Proteasome

Indexed keywords

5,6,4' TRIHYDROXY 7,3' DIMETHOXYFLAVONE; 6,7,4' TRIHYDROXYISOFLAVONE; APIGENIN; APIGENIN 6 HYDROXY; APIGENIN 6 HYDROXY 7 O BETA DEXTRO GLUCOSIDE; CAPSAICIN; CELASTROL; CHLOROGENIC ACID; CURCUMIN; DELPHINIDIN; DNA; GLYCITEIN; KAEMPFEROL; MALVIDIN 3 GALACTOSIDE; MALVIDIN CHLORIDE; MALVIN; MYRTILLIN; OENIN; PEDALITIN; PELARGONIDIN; PELARGONIN; PEONIDIN; PEONIDIN 3 GLUCOSIDE; PETUNIDIN CHLORIDE; POLYPHENOL; PROTEASOME; QUERCETIN; RUTOSIDE; SUMATRANOSIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT; BIOLOGICAL PRODUCT; PROTEINASE INHIBITOR;

EID: 79951708401     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800911794519815     Document Type: Article
Times cited : (10)

References (108)
  • 1
    • 0032535483 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway: On proteindeath and cell life
    • Ciechanover, A. The ubiquitin-proteasome pathway: on proteindeath and cell life. EMBO J. 1998, 17(24), 7151-7160.
    • (1998) EMBO J , vol.17 , Issue.24 , pp. 7151-7160
    • Ciechanover, A.1
  • 2
    • 23944474593 scopus 로고    scopus 로고
    • Intracellular protein degradation: From a vagueidea thru the lysosome and the ubiquitin-proteasome system andonto human diseases and drug targeting
    • Ciechanover, A. Intracellular protein degradation: from a vagueidea thru the lysosome and the ubiquitin-proteasome system andonto human diseases and drug targeting. Cell Death Differ. 2005,12(9), 1178-1190.
    • (2005) Cell Death Differ , vol.12 , Issue.9 , pp. 1178-1190
    • Ciechanover, A.1
  • 4
    • 0032488846 scopus 로고    scopus 로고
    • The proteasome:Paradigm of a self-compartmentalizing protease
    • Baumeister, W.; Walz, J.; Zuhl, F.; Seemuller, E. The proteasome:paradigm of a self-compartmentalizing protease. Cell 1998, 92(3),367-380.
    • (1998) Cell , vol.92 , Issue.3 , pp. 367-380
    • Baumeister, W.1    Walz, J.2    Zuhl, F.3    Seemuller, E.4
  • 6
    • 0029042511 scopus 로고
    • Crystal structure of the 20S proteasome from the archaeon T. acidophilumat 3.4 A resolution
    • Lowe, J.; Stock, D.; Jap, B.; Zwickl, P.; Baumeister, W.; Huber, R. Crystal structure of the 20S proteasome from the archaeon T. acidophilumat 3.4 A resolution. Science 1995, 268(5210), 533-539.
    • (1995) Science , vol.268 , Issue.5210 , pp. 533-539
    • Lowe, J.1    Stock, D.2    Jap, B.3    Zwickl, P.4    Baumeister, W.5    Huber, R.6
  • 7
    • 0027410433 scopus 로고
    • Evidence for the presenceof five distinct proteolytic components in the pituitary multicatalyticproteinase complex. Properties of two components cleavingbonds on the carboxyl side of branched chain and small neutralamino acids
    • Orlowski, M.; Cardozo, C.; Michaud, C. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalyticproteinase complex. Properties of two components cleavingbonds on the carboxyl side of branched chain and small neutralamino acids. Biochemistry 1993, 32(6), 1563-1572.
    • (1993) Biochemistry , vol.32 , Issue.6 , pp. 1563-1572
    • Orlowski, M.1    Cardozo, C.2    Michaud, C.3
  • 9
    • 0029060166 scopus 로고
    • Proteasome from Thermoplasma acidophilum: A threonineprotease
    • Seemuller, E.; Lupas, A.; Stock, D.; Lowe, J.; Huber, R.; Baumeister, W. Proteasome from Thermoplasma acidophilum: a threonineprotease. Science 1995, 268(5210), 579-582.
    • (1995) Science , vol.268 , Issue.5210 , pp. 579-582
    • Seemuller, E.1    Lupas, A.2    Stock, D.3    Lowe, J.4    Huber, R.5    Baumeister, W.6
  • 11
  • 14
    • 0033643742 scopus 로고    scopus 로고
    • The ubiquitinmediated proteolytic pathway: Mode of action and clinical implications
    • Ciechanover, A.; Orian, A.; Schwartz, A. L. The ubiquitinmediated proteolytic pathway: mode of action and clinical implications.J. Cell. Biochem. Suppl. 2000, 34, 40-51.
    • (2000) J. Cell. Biochem. Suppl , vol.34 , pp. 40-51
    • Ciechanover, A.1    Orian, A.2    Schwartz, A.L.3
  • 15
    • 0032429122 scopus 로고    scopus 로고
    • Novel dipeptidylproteasome inhibitors overcome Bcl-2 protective function and selectivelyaccumulate the cyclin-dependent kinase inhibitor p27 andinduce apoptosis in transformed, but not normal, human fibroblasts
    • An, B.; Goldfarb, R. H.; Siman, R.; Dou, Q. P. Novel dipeptidylproteasome inhibitors overcome Bcl-2 protective function and selectivelyaccumulate the cyclin-dependent kinase inhibitor p27 andinduce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ. 1998, 5(12), 1062-1075.
    • (1998) Cell Death Differ , vol.5 , Issue.12 , pp. 1062-1075
    • An, B.1    Goldfarb, R.H.2    Siman, R.3    Dou, Q.P.4
  • 16
    • 0030962262 scopus 로고    scopus 로고
    • p53-dependentinduction of apoptosis by proteasome inhibitors
    • Lopes, U. G.; Erhardt, P.; Yao, R.; Cooper, G. M. p53-dependentinduction of apoptosis by proteasome inhibitors. J. Biol. Chem.1997, 272(20), 12893-12896.
    • (1997) J. Biol. Chem , vol.272 , Issue.20 , pp. 12893-12896
    • Lopes, U.G.1    Erhardt, P.2    Yao, R.3    Cooper, G.M.4
  • 18
    • 0036355705 scopus 로고    scopus 로고
    • Regulation of apoptosis by the ubiquitin and proteasomepathway
    • Wojcik, C. Regulation of apoptosis by the ubiquitin and proteasomepathway. J. Cell. Mol. Med. 2002, 6(1), 25-48.
    • (2002) J. Cell. Mol. Med , vol.6 , Issue.1 , pp. 25-48
    • Wojcik, C.1
  • 19
    • 0037317840 scopus 로고    scopus 로고
    • Inhibiting the p53-MDM2 interaction: An importanttarget for cancer therapy
    • Chene, P. Inhibiting the p53-MDM2 interaction: an importanttarget for cancer therapy. Nat. Rev. Cancer 2003, 3(2), 102-109.
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.2 , pp. 102-109
    • Chene, P.1
  • 21
    • 0033961443 scopus 로고    scopus 로고
    • Role of p53 family members inapoptosis
    • Sheikh, M. S.; Fornace, A. J., Jr. Role of p53 family members inapoptosis. J. Cell. Physiol. 2000, 182(2), 171-181.
    • (2000) J. Cell. Physiol , vol.182 , Issue.2 , pp. 171-181
    • Sheikh, M.S.1    Fornace Jr., A.J.2
  • 22
    • 0034864799 scopus 로고    scopus 로고
    • Proteasome inhibitors: From researchtools to drug candidates
    • Kisselev, A. F.; Goldberg, A. L. Proteasome inhibitors: from researchtools to drug candidates. Chem. Biol. 2001, 8(8), 739-758.
    • (2001) Chem. Biol , vol.8 , Issue.8 , pp. 739-758
    • Kisselev, A.F.1    Goldberg, A.L.2
  • 24
    • 27244460815 scopus 로고    scopus 로고
    • Proteasome inhibitionand its clinical prospects in the treatment of hematologic andsolid malignancies
    • Ludwig, H.; Khayat, D.; Giaccone, G.; Facon, T. Proteasome inhibitionand its clinical prospects in the treatment of hematologic andsolid malignancies. Cancer 2005, 104(9), 1794-1807.
    • (2005) Cancer , vol.104 , Issue.9 , pp. 1794-1807
    • Ludwig, H.1    Khayat, D.2    Giaccone, G.3    Facon, T.4
  • 25
    • 54849417391 scopus 로고    scopus 로고
    • Natural polyphenols as proteasomemodulators and their role as anti-cancer compounds
    • Bonfili, L.; Cecarini, V.; Amici, M.; Cuccioloni, M.; Angeletti, M.; Keller, J. N.; Eleuteri, A. M. Natural polyphenols as proteasomemodulators and their role as anti-cancer compounds. FEBS J. 2008,275(22), 5512-5526.
    • (2008) FEBS J , vol.275 , Issue.22 , pp. 5512-5526
    • Bonfili, L.1    Cecarini, V.2    Amici, M.3    Cuccioloni, M.4    Angeletti, M.5    Keller, J.N.6    Eleuteri, A.M.7
  • 27
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologicstudies
    • Arts, I. C.; Hollman, P. C. Polyphenols and disease risk in epidemiologicstudies. Am. J. Clin. Nutr. 2005, 81 (1 Suppl), 317S-325S.
    • (2005) Am. J. Clin. Nutr , vol.81 , Issue.1 SUPPL.
    • Arts, I.C.1    Hollman, P.C.2
  • 28
    • 0034080382 scopus 로고    scopus 로고
    • Tea polyphenols: Prevention of cancerand optimizing health
    • discussion 1703S-1694S
    • Mukhtar, H.; Ahmad, N. Tea polyphenols: prevention of cancerand optimizing health. Am. J. Clin. Nutr. 2000, 71(6 Suppl),1698S-1702S; discussion 1703S-1694S.
    • (2000) Am. J. Clin. Nutr , vol.71 , Issue.6 SUPPL.
    • Mukhtar, H.1    Ahmad, N.2
  • 29
    • 14644417139 scopus 로고    scopus 로고
    • Effectiveness of moderate green tea consumption on antioxidativestatus and plasma lipid profile in humans
    • Erba, D.; Riso, P.; Bordoni, A.; Foti, P.; Biagi, P. L.; Testolin, G. Effectiveness of moderate green tea consumption on antioxidativestatus and plasma lipid profile in humans. J. Nutr. Biochem. 2005,16(3), 144-149.
    • (2005) J. Nutr. Biochem , vol.16 , Issue.3 , pp. 144-149
    • Erba, D.1    Riso, P.2    Bordoni, A.3    Foti, P.4    Biagi, P.L.5    Testolin, G.6
  • 30
    • 0032536175 scopus 로고    scopus 로고
    • Selectionof column and gradient elution system for the separation of catechinsin green tea using high-performance liquid chromatography
    • Dalluge, J. J.; Nelson, B. C.; Thomas, J. B.; Sander, L. C. Selectionof column and gradient elution system for the separation of catechinsin green tea using high-performance liquid chromatography.J. Chromatogr. A 1998, 793(2), 265-274.
    • (1998) J. Chromatogr. A , vol.793 , Issue.2 , pp. 265-274
    • Dalluge, J.J.1    Nelson, B.C.2    Thomas, J.B.3    Sander, L.C.4
  • 31
    • 34848821886 scopus 로고    scopus 로고
    • Curcuminattenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia
    • Jin, C. Y.; Lee, J. D.; Park, C.; Choi, Y. H.; Kim, G. Y. Curcuminattenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia. Acta Pharmacol. Sin. 2007,28(10), 1645-1651.
    • (2007) Acta Pharmacol. Sin , vol.28 , Issue.10 , pp. 1645-1651
    • Jin, C.Y.1    Lee, J.D.2    Park, C.3    Choi, Y.H.4    Kim, G.Y.5
  • 32
    • 51349137454 scopus 로고    scopus 로고
    • Curcumin inhibitsproliferation, invasion, angiogenesis and metastasis of differentcancers through interaction with multiple cell signaling proteins
    • Kunnumakkara, A. B.; Anand, P.; Aggarwal, B.B. Curcumin inhibitsproliferation, invasion, angiogenesis and metastasis of differentcancers through interaction with multiple cell signaling proteins.Cancer Lett. 2008, 269(2), 199-225.
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 199-225
    • Kunnumakkara, A.B.1    Anand, P.2    Aggarwal, B.B.3
  • 33
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention throughdietary antioxidants: Progress and promise
    • Khan, N.; Afaq, F.; Mukhtar, H. Cancer chemoprevention throughdietary antioxidants: progress and promise. Antioxid. Redox Signal.2008, 10(3), 475-510.
    • (2008) Antioxid. Redox Signal , vol.10 , Issue.3 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 34
    • 54749132655 scopus 로고    scopus 로고
    • Curcumin inhibits the proteasome activityin human colon cancer cells in vitro and in vivo
    • Milacic, V.; Banerjee, S.; Landis-Piwowar, K. R.; Sarkar, F. H.; Majumdar, A. P.; Dou, Q.P. Curcumin inhibits the proteasome activityin human colon cancer cells in vitro and in vivo. Cancer Res.2008, 68(18), 7283-7292.
    • (2008) Cancer Res , vol.68 , Issue.18 , pp. 7283-7292
    • Milacic, V.1    Banerjee, S.2    Landis-Piwowar, K.R.3    Sarkar, F.H.4    Majumdar, A.P.5    Dou, Q.P.6
  • 35
    • 1642564603 scopus 로고    scopus 로고
    • Inhibition ofproteasomal function by curcumin induces apoptosis through mitochondrialpathway
    • Jana, N. R.; Dikshit, P.; Goswami, A.; Nukina, N. Inhibition ofproteasomal function by curcumin induces apoptosis through mitochondrialpathway. J. Biol. Chem. 2004, 279(12), 11680-11685.
    • (2004) J. Biol. Chem , vol.279 , Issue.12 , pp. 11680-11685
    • Jana, N.R.1    Dikshit, P.2    Goswami, A.3    Nukina, N.4
  • 36
    • 33644891351 scopus 로고    scopus 로고
    • Curcumin enhances the polyglutamine-expanded truncated Nterminalhuntingtin-induced cell death by promoting proteasomalmalfunction
    • Dikshit, P.; Goswami, A.; Mishra, A.; Nukina, N.; Jana, N.R. Curcumin enhances the polyglutamine-expanded truncated Nterminalhuntingtin-induced cell death by promoting proteasomalmalfunction. Biochem. Biophys. Res. Commun. 2006, 342(4), 1323-1328.
    • (2006) Biochem. Biophys. Res. Commun , vol.342 , Issue.4 , pp. 1323-1328
    • Dikshit, P.1    Goswami, A.2    Mishra, A.3    Nukina, N.4    Jana, N.R.5
  • 37
    • 33744485564 scopus 로고    scopus 로고
    • Curcumin's biphasic hormetic response onproteasome activity and heat-shock protein synthesis in humankeratinocytes
    • Ali, R. E.; Rattan, S. I. Curcumin's biphasic hormetic response onproteasome activity and heat-shock protein synthesis in humankeratinocytes. Ann. N. Y. Acad. Sci. 2006, 1067, 394-399.
    • (2006) Ann. N. Y. Acad. Sci , vol.1067 , pp. 394-399
    • Ali, R.E.1    Rattan, S.I.2
  • 38
    • 33947411760 scopus 로고    scopus 로고
    • Dysregulation of the ubiquitin-proteasome system by curcuminsuppresses coxsackievirus B3 replication
    • Si, X.; Wang, Y.; Wong, J.; Zhang, J.; McManus, B. M.; Luo, H. Dysregulation of the ubiquitin-proteasome system by curcuminsuppresses coxsackievirus B3 replication. J. Virol. 2007, 81(7),3142-3150.
    • (2007) J. Virol , vol.81 , Issue.7 , pp. 3142-3150
    • Si, X.1    Wang, Y.2    Wong, J.3    Zhang, J.4    McManus, B.M.5    Luo, H.6
  • 39
    • 67650032601 scopus 로고    scopus 로고
    • New difluoro Knoevenagel condensates of curcumin, their Schiff bases and copper complexes as proteasome inhibitors and apoptosis inducers in cancer cells
    • Padhye, S.; Yang, H.; Jamadar, A.; Cui, Q. C.; Chavan, D.; Dominiak, K.; McKinney, J.; Banerjee, S.; Dou, Q. P.; Sarkar, F.H. New difluoro Knoevenagel condensates of curcumin, their Schiff bases and copper complexes as proteasome inhibitors and apoptosis inducers in cancer cells. Pharm. Res. 2009, 26(8), 1874-1880.
    • (2009) Pharm. Res , vol.26 , Issue.8 , pp. 1874-1880
    • Padhye, S.1    Yang, H.2    Jamadar, A.3    Cui, Q.C.4    Chavan, D.5    Dominiak, K.6    McKinney, J.7    Banerjee, S.8    Dou, Q.P.9    Sarkar, F.H.10
  • 40
    • 18044383342 scopus 로고    scopus 로고
    • Dietary flavonoids as proteasome inhibitorsand apoptosis inducers in human leukemia cells
    • Chen, D.; Daniel, K. G.; Chen, M. S.; Kuhn, D. J.; Landis-Piwowar, K. R.; Dou, Q. P. Dietary flavonoids as proteasome inhibitorsand apoptosis inducers in human leukemia cells. Biochem.Pharmacol. 2005, 69(10), 1421-1432.
    • (2005) Biochem.Pharmacol , vol.69 , Issue.10 , pp. 1421-1432
    • Chen, D.1    Daniel, K.G.2    Chen, M.S.3    Kuhn, D.J.4    Landis-Piwowar, K.R.5    Dou, Q.P.6
  • 41
    • 40349111004 scopus 로고    scopus 로고
    • Inhibitionof proteasome activity by the dietary flavonoid apigenin is associatedwith growth inhibition in cultured breast cancer cells andxenografts
    • Chen, D.; Landis-Piwowar, K. R.; Chen, M. S.; Dou, Q. P. Inhibitionof proteasome activity by the dietary flavonoid apigenin is associatedwith growth inhibition in cultured breast cancer cells andxenografts. Breast Cancer Res. 2007, 9(6), R80.
    • (2007) Breast Cancer Res , vol.9 , Issue.6
    • Chen, D.1    Landis-Piwowar, K.R.2    Chen, M.S.3    Dou, Q.P.4
  • 42
    • 74349115989 scopus 로고    scopus 로고
    • Apigenin, chrysin, and luteolin selectivelyinhibit chymotrypsin-like and trypsin-like proteasome catalytic activitiesin tumor cells
    • Wu, Y. X.; Fang, X. Apigenin, chrysin, and luteolin selectivelyinhibit chymotrypsin-like and trypsin-like proteasome catalytic activitiesin tumor cells. Planta Med. 2010, 76(2), 128-132.
    • (2010) Planta Med , vol.76 , Issue.2 , pp. 128-132
    • Wu, Y.X.1    Fang, X.2
  • 43
    • 33745797257 scopus 로고    scopus 로고
    • The influence of quercetin on the activity ofpurified 20S, 26S proteasome and proteasomal activity in isolatedcardiomyocytes]
    • Dosenko, V. E.; Nagibin, V. S.; Tumanovskaia, L. V.; Zagorii,VIu; Moibenko, A. A. [The influence of quercetin on the activity ofpurified 20S, 26S proteasome and proteasomal activity in isolatedcardiomyocytes]. Biomed. Khim. 2006, 52(2), 138-145.
    • (2006) Biomed. Khim , vol.52 , Issue.2 , pp. 138-145
    • Dosenko, V.E.1    Nagibin, V.S.2    Tumanovskaia, L.V.3
  • 44
    • 70350332192 scopus 로고    scopus 로고
    • Inhibitory Effect of Flavonoids on 26S ProteasomeActivity
    • Chang, T. L. Inhibitory Effect of Flavonoids on 26S ProteasomeActivity. J. Agric. Food. Chem. 2009, 57, 9706-9715.
    • (2009) J. Agric. Food. Chem , vol.57 , pp. 9706-9715
    • Chang, T.L.1
  • 45
    • 1042289764 scopus 로고    scopus 로고
    • Apigenin induces apoptosisthrough proteasomal degradation of HER2/neu in HER2/neuoverexpressingbreast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway
    • Way, T. D.; Kao, M. C.; Lin, J. K. Apigenin induces apoptosisthrough proteasomal degradation of HER2/neu in HER2/neuoverexpressingbreast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 2004, 279(6), 4479-4489.
    • (2004) J. Biol. Chem , vol.279 , Issue.6 , pp. 4479-4489
    • Way, T.D.1    Kao, M.C.2    Lin, J.K.3
  • 46
    • 56249131797 scopus 로고    scopus 로고
    • The flavonoid kaempferol sensitizes human gliomacells to TRAIL-mediated apoptosis by proteasomal degradation ofsurvivin
    • Siegelin, M. D.; Reuss, D. E.; Habel, A.; Herold-Mende, C.; vonDeimling, A. The flavonoid kaempferol sensitizes human gliomacells to TRAIL-mediated apoptosis by proteasomal degradation ofsurvivin. Mol. Cancer Ther. 2008, 7(11), 3566-3574.
    • (2008) Mol. Cancer Ther , vol.7 , Issue.11 , pp. 3566-3574
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Herold-Mende, C.4    Vondeimling, A.5
  • 47
    • 65949095390 scopus 로고    scopus 로고
    • Quercetin promotes degradation of survivin and thereby enhancesdeath-receptor-mediated apoptosis in glioma cells
    • Siegelin, M. D.; Reuss, D. E.; Habel, A.; Rami, A.; von Deimling,A. Quercetin promotes degradation of survivin and thereby enhancesdeath-receptor-mediated apoptosis in glioma cells. NeuroOncol. 2009, 11(2), 122-131.
    • (2009) NeuroOncol , vol.11 , Issue.2 , pp. 122-131
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Rami, A.4
  • 48
    • 34548590339 scopus 로고    scopus 로고
    • Silibinin sensitizes humanglioma cells to TRAIL-mediated apoptosis via DR5 up-regulationand down-regulation of c-FLIP and survivin
    • Son, Y. G.; Kim, E. H.; Kim, J. Y.; Kim, S. U.; Kwon, T. K.;Yoon, A. R.; Yun, C. O.; Choi, K. S. Silibinin sensitizes humanglioma cells to TRAIL-mediated apoptosis via DR5 up-regulationand down-regulation of c-FLIP and survivin. Cancer Res. 2007,67(17), 8274-8284.
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 8274-8284
    • Son, Y.G.1    Kim, E.H.2    Kim, J.Y.3    Kim, S.U.4    Kwon, T.5
  • 49
    • 77954882151 scopus 로고    scopus 로고
    • 5,6,3',4'-Tetrahydroxy-7-methoxyflavone as a Novel Potential ProteasomeInhibitor
    • Chang, T. L.; Ding, H. Y.; Teng, K. N.; Fang, Y. C. 5,6,3',4'-Tetrahydroxy-7-methoxyflavone as a Novel Potential ProteasomeInhibitor. Planta Med. 2010, 76(10), 987-94.
    • (2010) Planta Med , vol.76 , Issue.10 , pp. 987-994
    • Chang, T.L.1    Ding, H.Y.2    Teng, K.N.3    Fang, Y.C.4
  • 50
    • 44649181057 scopus 로고    scopus 로고
    • Inhibition of proteasome activityby anthocyanins and anthocyanidins
    • Dreiseitel, A.; Schreier, P.; Oehme, A.; Locher, S.; Rogler, G.;Piberger, H.; Hajak, G.; Sand, P. G. Inhibition of proteasome activityby anthocyanins and anthocyanidins. Biochem. Biophys. Res.Commun. 2008, 372(1), 57-61.
    • (2008) Biochem. Biophys. Res.Commun , vol.372 , Issue.1 , pp. 57-61
    • Dreiseitel, A.1    Schreier, P.2    Oehme, A.3    Locher, S.4
  • 51
    • 0037438997 scopus 로고    scopus 로고
    • Oxygen radical absorbing capacity ofphenolics in blueberries, cranberries, chokeberries, and lingonberries
    • Zheng, W.; Wang, S. Y. Oxygen radical absorbing capacity ofphenolics in blueberries, cranberries, chokeberries, and lingonberries.J. Agric. Food. Chem. 2003, 51(2), 502-509.
    • (2003) J. Agric. Food. Chem , vol.51 , Issue.2 , pp. 502-509
    • Zheng, W.1    Wang, S.Y.2
  • 52
    • 0032986801 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activitiesof anthocyanins and their aglycon, cyanidin, from tart cherries
    • Wang, H.; Nair, M. G.; Strasburg, G. M.; Chang, Y. C.; Booren, A.M.; Gray, J. I.; DeWitt, D. L. Antioxidant and antiinflammatory activitiesof anthocyanins and their aglycon, cyanidin, from tart cherries.J. Nat. Prod. 1999, 62(2), 294-296.
    • (1999) J. Nat. Prod , vol.62 , Issue.2 , pp. 294-296
    • Wang, H.1    Nair, M.G.2    Strasburg, G.M.3    Chang, Y.C.4    Booren, A.M.5    Gray, J.I.6    Dewitt, D.L.7
  • 53
    • 0037333332 scopus 로고    scopus 로고
    • Potential mechanisms of cancer chemoprevention byanthocyanins
    • Hou, D. X. Potential mechanisms of cancer chemoprevention byanthocyanins. Curr. Mol. Med. 2003, 3(2), 149-159.
    • (2003) Curr. Mol. Med , vol.3 , Issue.2 , pp. 149-159
    • Hou, D.X.1
  • 54
    • 0036902931 scopus 로고    scopus 로고
    • Feeding rats diets enriched in lowbush blueberries forsix weeks decreases ischemia-induced brain damage
    • Sweeney, M. I.; Kalt, W.; MacKinnon, S. L.; Ashby, J.; Gottschall-Pass, K. T. Feeding rats diets enriched in lowbush blueberries forsix weeks decreases ischemia-induced brain damage. Nutr. Neurosci.2002, 5(6), 427-431.
    • (2002) Nutr. Neurosci , vol.5 , Issue.6 , pp. 427-431
    • Sweeney, M.I.1    Kalt, W.2    Mackinnon, S.L.3    Ashby, J.4    Gottschall-Pass, K.T.5
  • 55
    • 34548010792 scopus 로고    scopus 로고
    • Neuroprotective effects of anthocyaninsand their in vivo metabolites in SH-SY5Y cells
    • Tarozzi, A.; Morroni, F.; Hrelia, S.; Angeloni, C.; Marchesi, A.;Cantelli-Forti, G.; Hrelia, P. Neuroprotective effects of anthocyaninsand their in vivo metabolites in SH-SY5Y cells. Neurosci. Lett.2007, 424(1), 36-40.
    • (2007) Neurosci. Lett , vol.424 , Issue.1 , pp. 36-40
    • Tarozzi, A.1    Morroni, F.2    Hrelia, S.3    Angeloni, C.4
  • 56
    • 77954687171 scopus 로고    scopus 로고
    • Mulberry fruit protects dopaminergic neuronsin toxin-induced Parkinson's disease models
    • Kim, H. G.; Ju, M. S.; Shim, J. S.; Kim, M. C.; Lee, S. H.; Huh, Y.;Kim, S. Y.; Oh, M. S. Mulberry fruit protects dopaminergic neuronsin toxin-induced Parkinson's disease models. Br. J. Nutr.2010, 1-9.
    • (2010) Br. J. Nutr , pp. 1-9
    • Kim, H.G.1    Ju, M.S.2    Shim, J.S.3    Kim, M.C.4    Lee, S.H.5
  • 58
    • 33947113796 scopus 로고    scopus 로고
    • Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis
    • Manju, V.; Nalini, N. Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis. CellBiochem. Funct. 2007, 25(2), 189-194.
    • (2007) CellBiochem. Funct , vol.25 , Issue.2 , pp. 189-194
    • Manju, V.1    Nalini, N.2
  • 59
    • 7444272077 scopus 로고    scopus 로고
    • Luteolin inhibits vascular endothelial growthfactor-induced angiogenesis; inhibition of endothelial cell survivaland proliferation by targeting phosphatidylinositol 3'-kinase activity
    • Bagli, E.; Stefaniotou, M.; Morbidelli, L.; Ziche, M.; Psillas, K.;Murphy, C.; Fotsis, T. Luteolin inhibits vascular endothelial growthfactor-induced angiogenesis; inhibition of endothelial cell survivaland proliferation by targeting phosphatidylinositol 3'-kinase activity.Cancer Res. 2004, 64(21), 7936-7946.
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7936-7946
    • Bagli, E.1    Stefaniotou, M.2    Morbidelli, L.3    Ziche, M.4
  • 60
    • 12844286313 scopus 로고    scopus 로고
    • Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis
    • Leung, H. W.; Wu, C. H.; Lin, C. H.; Lee, H. Z. Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis. Eur. J. Pharmacol. 2005, 508(1-3), 77-83.
    • (2005) Eur. J. Pharmacol , vol.508 , Issue.1-3 , pp. 77-83
    • Leung, H.W.1    Wu, C.H.2    Lin, C.H.3    Lee, H.Z.4
  • 61
    • 33646411225 scopus 로고    scopus 로고
    • Luteolin promotesdegradation in signal transducer and activator of transcription 3 inhuman hepatoma cells: An implication for the antitumor potential offlavonoids
    • Selvendiran, K.; Koga, H.; Ueno, T.; Yoshida, T.; Maeyama, M.;Torimura, T.; Yano, H.; Kojiro, M.; Sata, M. Luteolin promotesdegradation in signal transducer and activator of transcription 3 inhuman hepatoma cells: an implication for the antitumor potential offlavonoids. Cancer Res. 2006, 66(9), 4826-4834.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4826-4834
    • Selvendiran, K.1    Koga, H.2    Ueno, T.3    Yoshida, T.4
  • 62
    • 7044236785 scopus 로고    scopus 로고
    • Luteolin sensitizes tumor necrosisfactor-alpha-induced apoptosis in human tumor cells
    • Shi, R. X.; Ong, C. N.; Shen, H. M. Luteolin sensitizes tumor necrosisfactor-alpha-induced apoptosis in human tumor cells. Oncogene, 2004, 23(46), 7712-7721.
    • (2004) Oncogene , vol.23 , Issue.46 , pp. 7712-7721
    • Shi, R.X.1    Ong, C.N.2    Shen, H.M.3
  • 63
    • 34250615454 scopus 로고    scopus 로고
    • The olive constituent oleuropein exhibits proteasome stimulatoryproperties in vitro and confers life span extension of human embryonicfibroblasts
    • Katsiki, M.; Chondrogianni, N.; Chinou, I.; Rivett, A. J.; Gonos, E.S. The olive constituent oleuropein exhibits proteasome stimulatoryproperties in vitro and confers life span extension of human embryonicfibroblasts. Rejuvenation Res. 2007, 10(2), 157-172.
    • (2007) Rejuvenation Res , vol.10 , Issue.2 , pp. 157-172
    • Katsiki, M.1    Chondrogianni, N.2    Chinou, I.3    Rivett, A.J.4    Gonos, E.S.5
  • 64
    • 75449090789 scopus 로고    scopus 로고
    • Anticancer agentsderived from natural products
    • Liu, E. H.; Qi, L. W.; Wu, Q.; Peng, Y. B.; Li, P. Anticancer agentsderived from natural products. Mini Rev. Med. Chem. 2009, 9(13),1547-1555.
    • (2009) Mini Rev. Med. Chem , vol.9 , Issue.13 , pp. 1547-1555
    • Liu, E.H.1    Qi, L.W.2    Wu, Q.3    Peng, Y.B.4    Li, P.5
  • 65
    • 33144456303 scopus 로고    scopus 로고
    • Resveratrol enhances radiosensitivity of humannon-small cell lung cancer NCI-H838 cells accompanied by inhibitionof nuclear factor-kappa B activation
    • Liao, H. F.; Kuo, C. D.; Yang, Y. C.; Lin, C. P.; Tai, H. C.; Chen,Y. Y.; Chen, Y. J. Resveratrol enhances radiosensitivity of humannon-small cell lung cancer NCI-H838 cells accompanied by inhibitionof nuclear factor-kappa B activation. J. Radiat. Res. (Tokyo)2005, 46(4), 387-393.
    • (2005) J. Radiat. Res. (Tokyo) , vol.46 , Issue.4 , pp. 387-393
    • Liao, H.F.1    Kuo, C.D.2    Yang, Y.C.3    Lin, C.P.4    Tai, H.C.5
  • 66
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
    • Marambaud, P.; Zhao, H.; Davies, P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J. Biol. Chem.2005, 280(45), 37377-37382.
    • (2005) J. Biol. Chem , vol.280 , Issue.45 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 67
    • 33644644970 scopus 로고    scopus 로고
    • Effect of polyphenolic compounds on the proteolyticactivities of constitutive and immuno-proteasomes
    • Pettinari, A.; Amici, M.; Cuccioloni, M.; Angeletti, M.; Fioretti, E.;Eleuteri, A. M. Effect of polyphenolic compounds on the proteolyticactivities of constitutive and immuno-proteasomes. Antioxid.Redox Signal. 2006, 8(1-2), 121-129.
    • (2006) Antioxid.Redox Signal , vol.8 , Issue.1-2 , pp. 121-129
    • Pettinari, A.1    Amici, M.2    Cuccioloni, M.3    Angeletti, M.4
  • 68
    • 65249101693 scopus 로고    scopus 로고
    • Homology modeling and docking analysis of the interactionbetween polyphenols and mammalian 20S proteasomes
    • Mozzicafreddo, M.; Cuccioloni, M.; Cecarini, V.; Eleuteri, A. M.;Angeletti, M. Homology modeling and docking analysis of the interactionbetween polyphenols and mammalian 20S proteasomes. J.Chem. Inf. Model. 2009, 49(2), 401-409.
    • (2009) J.Chem. Inf. Model , vol.49 , Issue.2 , pp. 401-409
    • Mozzicafreddo, M.1    Cuccioloni, M.2    Cecarini, V.3    Eleuteri, A.4
  • 69
    • 0034798016 scopus 로고    scopus 로고
    • Tannic acid potently inhibitstumor cell proteasome activity, increases p27 and Bax expression,and induces G1 arrest and apoptosis
    • Nam, S.; Smith, D. M.; Dou, Q. P. Tannic acid potently inhibitstumor cell proteasome activity, increases p27 and Bax expression,and induces G1 arrest and apoptosis. Cancer Epidemiol. BiomarkersPrev. 2001, 10(10), 1083-1088.
    • (2001) Cancer Epidemiol. BiomarkersPrev , vol.10 , Issue.10 , pp. 1083-1088
    • Nam, S.1    Smith, D.M.2    Dou, Q.P.3
  • 70
    • 73749087154 scopus 로고    scopus 로고
    • Naturallyoccurring phenolic acids inhibit 12-O-tetradecanoylphorbol-13-acetate induced NF-kappaB, iNOS and COX-2 activation in mouseepidermis
    • Cichocki, M.; Blumczynska, J.; Baer-Dubowska, W. Naturallyoccurring phenolic acids inhibit 12-O-tetradecanoylphorbol-13-acetate induced NF-kappaB, iNOS and COX-2 activation in mouseepidermis. Toxicology 2010, 268(1-2), 118-124.
    • (2010) Toxicology , vol.268 , Issue.1-2 , pp. 118-124
    • Cichocki, M.1    Blumczynska, J.2    Baer-Dubowska, W.3
  • 71
    • 1342326225 scopus 로고    scopus 로고
    • Inhibition of proteasome activity by various fruits and vegetables is associated with cancer cell death
    • Chen, M. S.; Chen, D.; Dou, Q. P. Inhibition of proteasome activity by various fruits and vegetables is associated with cancer cell death. In Vivo 2004, 18(1), 73-80.
    • (2004) In Vivo , vol.18 , Issue.1 , pp. 73-80
    • Chen, M.S.1    Chen, D.2    Dou, Q.P.3
  • 72
    • 3042717275 scopus 로고    scopus 로고
    • A natural musaceasplant extract inhibits proteasome activity and induces apoptosis selectivelyin human tumor and transformed, but not normal and nontransformed,cells
    • Kazi, A.; Urbizu, D. A.; Kuhn, D. J.; Acebo, A. L.; Jackson, E. R.;Greenfelder, G. P.; Kumar, N. B.; Dou, Q. P. A natural musaceasplant extract inhibits proteasome activity and induces apoptosis selectivelyin human tumor and transformed, but not normal and nontransformed,cells. Int. J. Mol. Med. 2003, 12(6), 879-887.
    • (2003) Int. J. Mol. Med , vol.12 , Issue.6 , pp. 879-887
    • Kazi, A.1    Urbizu, D.A.2    Kuhn, D.J.3    Acebo, A.L.4    Jackson, E.5
  • 73
    • 42649136205 scopus 로고    scopus 로고
    • Wheat sprout extract induces changes on 20S proteasomes functionality
    • Amici, M.; Bonfili, L.; Spina, M.; Cecarini, V.; Calzuola, I.; Marsili,V.; Angeletti, M.; Fioretti, E.; Tacconi, R.; Gianfranceschi, G.L.; Eleuteri, A. M. Wheat sprout extract induces changes on 20S proteasomes functionality. Biochimie 2008, 90(5), 790-801.
    • (2008) Biochimie , vol.90 , Issue.5 , pp. 790-801
    • Amici, M.1    Bonfili, L.2    Spina, M.3    Cecarini, V.4    Calzuola, I.5
  • 74
    • 67651215708 scopus 로고    scopus 로고
    • Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation
    • Bonfili, L.; Amici, M.; Cecarini, V.; Cuccioloni, M.; Tacconi, R.;Angeletti, M.; Fioretti, E.; Keller, J. N.; Eleuteri, A. M. Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation. Biochimie 2009, 91(9), 1131-1144.
    • (2009) Biochimie , vol.91 , Issue.9 , pp. 1131-1144
    • Bonfili, L.1    Amici, M.2    Cecarini, V.3    Cuccioloni, M.4
  • 76
    • 37849018320 scopus 로고    scopus 로고
    • Antioxidants block proteasome inhibitor functionin endometrial carcinoma cells
    • Llobet, D.; Eritja, N.; Encinas, M.; Sorolla, A.; Yeramian, A.;Schoenenberger, J. A.; Llombart-Cussac, A.; Marti, R. M.; Matias-Guiu, X.; Dolcet, X. Antioxidants block proteasome inhibitor functionin endometrial carcinoma cells. Anticancer Drugs 2008, 19(2), 115-124.
    • (2008) Anticancer Drugs , vol.19 , Issue.2 , pp. 115-124
    • Llobet, D.1    Eritja, N.2    Encinas, M.3    Sorolla, A.4
  • 77
    • 70349303770 scopus 로고    scopus 로고
    • Ascorbic acid inhibits antitumoractivity of bortezomib in vivo
    • Perrone, G.; Hideshima, T.; Ikeda, H.; Okawa, Y.; Calabrese, E.;Gorgun, G.; Santo, L.; Cirstea, D.; Raje, N.; Chauhan, D.; Baccarani,M.; Cavo, M.; Anderson, K. C. Ascorbic acid inhibits antitumoractivity of bortezomib in vivo. Leukemia 2009, 23(9), 1679-1686.
    • (2009) Leukemia , vol.23 , Issue.9 , pp. 1679-1686
    • Perrone, G.1    Hideshima, T.2    Ikeda, H.3    Okawa, Y.4
  • 78
  • 79
    • 67650475322 scopus 로고    scopus 로고
    • Natural polyphenols antagonize the antimyeloma activity ofproteasome inhibitor bortezomib by direct chemical interaction
    • Kim, T. Y.; Park, J.; Oh, B.; Min, H. J.; Jeong, T. S.; Lee, J. H.;Suh, C.; Cheong, J. W.; Kim, H. J.; Yoon, S. S.; Park, S. B.; Lee,D. S. Natural polyphenols antagonize the antimyeloma activity ofproteasome inhibitor bortezomib by direct chemical interaction. Br.J. Haematol. 2009, 146(3), 270-281.
    • (2009) Br.J. Haematol , vol.146 , Issue.3 , pp. 270-281
    • Kim, T.Y.1    Park, J.2    Oh, B.3    Min, H.J.4    Jeong, T.S.5    Lee, J.6
  • 80
    • 66949155833 scopus 로고    scopus 로고
    • Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors
    • Golden, E. B.; Lam, P. Y.; Kardosh, A.; Gaffney, K. J.; Cadenas,E.; Louie, S. G.; Petasis, N. A.; Chen, T. C.; Schonthal, A. H.Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors. Blood 2009, 113(23), 5927-5937.
    • (2009) Blood , vol.113 , Issue.23 , pp. 5927-5937
    • Golden, E.B.1    Lam, P.Y.2    Kardosh, A.3    Gaffney, K.J.4
  • 81
    • 33750209537 scopus 로고    scopus 로고
    • A novel proteasomeinhibitor NPI-0052 as an anticancer therapy
    • Chauhan, D.; Hideshima, T.; Anderson, K. C. A novel proteasomeinhibitor NPI-0052 as an anticancer therapy. Br. J. Cancer 2006,95(8), 961-965.
    • (2006) Br. J. Cancer , vol.95 , Issue.8 , pp. 961-965
    • Chauhan, D.1    Hideshima, T.2    Anderson, K.C.3
  • 82
    • 77951682116 scopus 로고    scopus 로고
    • Pharmacodynamic and efficacystudies of the novel proteasome inhibitor NPI-0052 (marizomib) ina human plasmacytoma xenograft murine model
    • Singh, A. V.; Palladino, M. A.; Lloyd, G. K.; Potts, B. C.;Chauhan, D.; Anderson, K. C. Pharmacodynamic and efficacystudies of the novel proteasome inhibitor NPI-0052 (marizomib) ina human plasmacytoma xenograft murine model. Br. J. Haematol.2010, 149(4), 550-559.
    • (2010) Br. J. Haematol , vol.149 , Issue.4 , pp. 550-559
    • Singh, A.V.1    Palladino, M.A.2    Lloyd, G.K.3    Potts, B.4
  • 83
    • 0037457481 scopus 로고    scopus 로고
    • Disulfiram-mediated inhibitionof NF-kappaB activity enhances cytotoxicity of 5-fluorouracilin human colorectal cancer cell lines
    • Wang, W.; McLeod, H. L.; Cassidy, J. Disulfiram-mediated inhibitionof NF-kappaB activity enhances cytotoxicity of 5-fluorouracilin human colorectal cancer cell lines. Int. J. Cancer 2003, 104(4),504-511.
    • (2003) Int. J. Cancer , vol.104 , Issue.4 , pp. 504-511
    • Wang, W.1    McLeod, H.L.2    Cassidy, J.3
  • 84
    • 4644235752 scopus 로고    scopus 로고
    • Disulfiraminhibits activating transcription factor/cyclic AMPresponsiveelement binding protein and human melanoma growthin a metal-dependent manner in vitro, in mice and in a patient withmetastatic disease
    • Brar, S. S.; Grigg, C.; Wilson, K. S.; Holder, W. D., Jr.; Dreau, D.;Austin, C.; Foster, M.; Ghio, A. J.; Whorton, A. R.; Stowell, G. W.;Whittall, L. B.; Whittle, R. R.; White, D. P.; Kennedy, T. P. Disulfiraminhibits activating transcription factor/cyclic AMPresponsiveelement binding protein and human melanoma growthin a metal-dependent manner in vitro, in mice and in a patient withmetastatic disease. Mol. Cancer Ther. 2004, 3(9), 1049-1060.
    • (2004) Mol. Cancer Ther , vol.3 , Issue.9 , pp. 1049-1060
    • Brar, S.S.1    Grigg, C.2    Wilson, K.S.3    Holder Jr., W.D.4
  • 85
    • 0036050582 scopus 로고    scopus 로고
    • Disulfiram induces apoptosis inhuman melanoma cells: A redox-related process
    • Cen, D.; Gonzalez, R. I.; Buckmeier, J. A.; Kahlon, R. S.; Tohidian,N. B.; Meyskens, F. L., Jr. Disulfiram induces apoptosis inhuman melanoma cells: a redox-related process. Mol. Cancer Ther.2002, 1(3), 197-204.
    • (2002) Mol. Cancer Ther , vol.1 , Issue.3 , pp. 197-204
    • Cen, D.1    Gonzalez, R.I.2    Buckmeier, J.A.3    Kahlon, R.S.4
  • 86
    • 0142148099 scopus 로고    scopus 로고
    • Inhibition of invasionand angiogenesis by zinc-chelating agent disulfiram
    • Shian, S. G.; Kao, Y. R.; Wu, F. Y.; Wu, C. W. Inhibition of invasionand angiogenesis by zinc-chelating agent disulfiram. Mol.Pharmacol. 2003, 64(5), 1076-1084.
    • (2003) Mol.Pharmacol , vol.64 , Issue.5 , pp. 1076-1084
    • Shian, S.G.1    Kao, Y.R.2    Wu, F.Y.3    Wu, C.W.4
  • 87
    • 27644562277 scopus 로고    scopus 로고
    • A novel orallyactive proteasome inhibitor induces apoptosis in multiple myelomacells with mechanisms distinct from Bortezomib
    • Chauhan, D.; Catley, L.; Li, G.; Podar, K.; Hideshima, T.; Velankar,M.; Mitsiades, C.; Mitsiades, N.; Yasui, H.; Letai, A.; Ovaa,H.; Berkers, C.; Nicholson, B.; Chao, T. H.; Neuteboom, S. T.;Richardson, P.; Palladino, M. A.; Anderson, K. C. A novel orallyactive proteasome inhibitor induces apoptosis in multiple myelomacells with mechanisms distinct from Bortezomib. Cancer Cell.2005, 8(5), 407-419.
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 407-419
    • Chauhan, D.1    Catley, L.2    Li, G.3    Podar, K.4    Hideshima, T.5
  • 88
    • 33646137808 scopus 로고    scopus 로고
    • Crystal structures of SalinosporamideA (NPI-0052) and B (NPI-0047) in complex with the 20Sproteasome reveal important consequences of beta-lactone ringopening and a mechanism for irreversible binding
    • Groll, M.; Huber, R.; Potts, B. C. Crystal structures of SalinosporamideA (NPI-0052) and B (NPI-0047) in complex with the 20Sproteasome reveal important consequences of beta-lactone ringopening and a mechanism for irreversible binding. J. Am. Chem.Soc. 2006, 128(15), 5136-5141.
    • (2006) J. Am. Chem.Soc , vol.128 , Issue.15 , pp. 5136-5141
    • Groll, M.1    Huber, R.2    Potts, B.C.3
  • 89
    • 10044231524 scopus 로고    scopus 로고
    • Activity-guided fractionation of the leaves of Ormosia sumatranausing a proteasome inhibition assay
    • Su, B. N.; Hwang, B. Y.; Chai, H.; Carcache-Blanco, E. J.; Kardono,L. B.; Afriastini, J. J.; Riswan, S.; Wild, R.; Laing, N.;Farnsworth, N. R.; Cordell, G. A.; Swanson, S. M.; Kinghorn, A.D. Activity-guided fractionation of the leaves of Ormosia sumatranausing a proteasome inhibition assay. J. Nat. Prod. 2004, 67(11), 1911-1914.
    • (2004) J. Nat. Prod , vol.67 , Issue.11 , pp. 1911-1914
    • Su, B.N.1    Hwang, B.Y.2    Chai, H.3    Carcache-Blanco, E.J.4
  • 90
    • 33846454701 scopus 로고    scopus 로고
    • The tumor proteasome is a primarytarget for the natural anticancer compound Withaferin A isolatedfrom Indian winter cherry
    • Yang, H.; Shi, G.; Dou, Q. P. The tumor proteasome is a primarytarget for the natural anticancer compound Withaferin A isolatedfrom Indian winter cherry. Mol. Pharmacol. 2007, 71(2), 426-437.
    • (2007) Mol. Pharmacol , vol.71 , Issue.2 , pp. 426-437
    • Yang, H.1    Shi, G.2    Dou, Q.P.3
  • 91
    • 77950373388 scopus 로고    scopus 로고
    • Capsaicin induces apoptosisthrough ubiquitin-proteasome system dysfunction
    • Maity, R.; Sharma, J.; Jana, N. R. Capsaicin induces apoptosisthrough ubiquitin-proteasome system dysfunction. J. Cell. Biochem.2010, 109(5), 933-942
    • (2010) J. Cell. Biochem , vol.109 , Issue.5 , pp. 933-942
    • Maity, R.1    Sharma, J.2    Jana, N.R.3
  • 92
    • 33646406554 scopus 로고    scopus 로고
    • Celastrol, atriterpene extracted from the Chinese Thunder of God Vine, is apotent proteasome inhibitor and suppresses human prostate cancergrowth in nude mice
    • Yang, H.; Chen, D.; Cui, Q. C.; Yuan, X.; Dou, Q. P. Celastrol, atriterpene extracted from the Chinese Thunder of God Vine, is apotent proteasome inhibitor and suppresses human prostate cancergrowth in nude mice. Cancer Res. 2006, 66(9), 4758-4765.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4758-4765
    • Yang, H.1    Chen, D.2    Cui, Q.C.3    Yuan, X.4    Dou, Q.P.5
  • 93
    • 34250158095 scopus 로고    scopus 로고
    • Curcumin reverses breast tumorexosomes mediated immune suppression of NK cell tumor cytotoxicity
    • Zhang, H. G.; Kim, H.; Liu, C.; Yu, S.; Wang, J.; Grizzle, W. E.;Kimberly, R. P.; Barnes, S. Curcumin reverses breast tumorexosomes mediated immune suppression of NK cell tumor cytotoxicity. Biochim. Biophys. Acta 2007, 1773(7), 1116-1123.
    • (2007) Biochim. Biophys. Acta , vol.1773 , Issue.7 , pp. 1116-1123
    • Zhang, H.G.1    Kim, H.2    Liu, C.3    Yu, S.4    Wang, J.5    Grizzle, W.6
  • 94
    • 9144264926 scopus 로고    scopus 로고
    • Induction of proteasomeexpression in skeletal muscle is attenuated by inhibitors of NFkappaBactivation
    • Wyke, S. M.; Russell, S. T.; Tisdale, M. J. Induction of proteasomeexpression in skeletal muscle is attenuated by inhibitors of NFkappaBactivation. Br. J. Cancer 2004, 91(9), 1742-1750.
    • (2004) Br. J. Cancer , vol.91 , Issue.9 , pp. 1742-1750
    • Wyke, S.M.1    Russell, S.T.2    Tisdale, M.J.3
  • 96
    • 14844303304 scopus 로고    scopus 로고
    • Sensitization of taxol-induced apoptosis by curcumininvolves down-regulation of nuclear factor-kappaB and theserine/threonine kinase Akt and is independent of tubulin polymerization
    • Bava, S. V.; Puliappadamba, V. T.; Deepti, A.; Nair, A.; Karunagaran,D.; Anto, R. J. Sensitization of taxol-induced apoptosis by curcumininvolves down-regulation of nuclear factor-kappaB and theserine/threonine kinase Akt and is independent of tubulin polymerization. J. Biol. Chem. 2005, 280(8), 6301-6308.
    • (2005) J. Biol. Chem , vol.280 , Issue.8 , pp. 6301-6308
    • Bava, S.V.1    Puliappadamba, V.T.2    Deepti, A.3    Nair, A.4    Karunagaran, D.5    Anto, R.J.6
  • 97
    • 19344367506 scopus 로고    scopus 로고
    • Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancercells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
    • Notarbartolo, M.; Poma, P.; Perri, D.; Dusonchet, L.; Cervello, M.;D'Alessandro, N. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancercells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression. Cancer Lett. 2005, 224(1), 53-65.
    • (2005) Cancer Lett , vol.224 , Issue.1 , pp. 53-65
    • Notarbartolo, M.1    Poma, P.2    Perri, D.3    Dusonchet, L.4    Cervello, M.5    D'Alessandro, N.6
  • 99
    • 48149095229 scopus 로고    scopus 로고
    • The flavonoid fisetin promotes nerve cell survival fromtrophic factor withdrawal by enhancement of proteasome activity
    • Maher, P. The flavonoid fisetin promotes nerve cell survival fromtrophic factor withdrawal by enhancement of proteasome activity.Arch. Biochem. Biophys. 2008, 476(2), 139-144.
    • (2008) Arch. Biochem. Biophys , vol.476 , Issue.2 , pp. 139-144
    • Maher, P.1
  • 100
    • 66749159615 scopus 로고    scopus 로고
    • Dietary flavonoid fisetin induces a forcedexit from mitosis by targeting the mitotic spindle checkpoint
    • Salmela, A. L.; Pouwels, J.; Varis, A.; Kukkonen, A. M.;Toivonen, P.; Halonen, P. K.; Perala, M.; Kallioniemi, O.; Gorbsky,G. J.; Kallio, M. J. Dietary flavonoid fisetin induces a forcedexit from mitosis by targeting the mitotic spindle checkpoint. Carcinogenesis 2009, 30(6), 1032-1040.
    • (2009) Carcinogenesis , vol.30 , Issue.6 , pp. 1032-1040
    • Salmela, A.L.1    Pouwels, J.2    Varis, A.3    Kukkonen, A.4
  • 101
    • 0042261670 scopus 로고    scopus 로고
    • Inhibition of the proteasome activity, a novel mechanism associatedwith the tumor cell apoptosis-inducing ability of genistein
    • Kazi, A.; Daniel, K. G.; Smith, D. M.; Kumar, N. B.; Dou, Q. P.Inhibition of the proteasome activity, a novel mechanism associatedwith the tumor cell apoptosis-inducing ability of genistein.Biochem. Pharmacol. 2003, 66(6), 965-976.
    • (2003) Biochem. Pharmacol , vol.66 , Issue.6 , pp. 965-976
    • Kazi, A.1    Daniel, K.G.2    Smith, D.M.3    Kumar, N.B.4    Dou, Q.P.5
  • 102
    • 5644227426 scopus 로고    scopus 로고
    • Inhibition of proliferation and induction ofapoptosis by genistein in colon cancer HT-29 cells
    • Yu, Z.; Li, W.; Liu, F. Inhibition of proliferation and induction ofapoptosis by genistein in colon cancer HT-29 cells. Cancer Lett.2004, 215(2), 159-166.
    • (2004) Cancer Lett , vol.215 , Issue.2 , pp. 159-166
    • Yu, Z.1    Li, W.2    Liu, F.3
  • 103
    • 33645824142 scopus 로고    scopus 로고
    • Genistein suppresses proliferation and MET oncogene expression and induces EGR-1 tumor suppressor expression in immortalized human breast epithelial cells
    • Singletary, K.; Ellington, A. Genistein suppresses proliferation and MET oncogene expression and induces EGR-1 tumor suppressor expression in immortalized human breast epithelial cells. Anticancer Res. 2006, 26(2A), 1039-1048.
    • (2006) Anticancer Res , vol.26 , Issue.2 A , pp. 1039-1048
    • Singletary, K.1    Ellington, A.2
  • 104
    • 54849425348 scopus 로고    scopus 로고
    • Quercetin-induced ubiquitination and down-regulation of Her-2/neu
    • Jeong, J. H.; An, J. Y.; Kwon, Y. T.; Li, L. Y.; Lee, Y. J. Quercetin-induced ubiquitination and down-regulation of Her-2/neu. J.Cell. Biochem. 2008, 105(2), 585-595.
    • (2008) J.Cell. Biochem , vol.105 , Issue.2 , pp. 585-595
    • Jeong, J.H.1    An, J.Y.2    Kwon, Y.T.3    Li, L.Y.4    Lee, Y.J.5
  • 105
    • 34447092454 scopus 로고    scopus 로고
    • Quercetin mediates preferential degradationof oncogenic Ras and causes autophagy in Ha-RAStransformedhuman colon cells
    • Psahoulia, F. H.; Moumtzi, S.; Roberts, M. L.; Sasazuki, T.;Shirasawa, S.; Pintzas, A. Quercetin mediates preferential degradationof oncogenic Ras and causes autophagy in Ha-RAStransformedhuman colon cells. Carcinogenesis 2007, 28(5), 1021-1031.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 1021-1031
    • Psahoulia, F.H.1    Moumtzi, S.2    Roberts, M.L.3
  • 106
    • 57349169369 scopus 로고    scopus 로고
    • Quercetin sensitizes human hepatoma cells to TRAILinducedapoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
    • Kim, J. Y.; Kim, E. H.; Park, S. S.; Lim, J. H.; Kwon, T. K.; Choi,K. S. Quercetin sensitizes human hepatoma cells to TRAILinducedapoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J. Cell. Biochem. 2008, 105(6), 1386-1398.
    • (2008) J. Cell. Biochem , vol.105 , Issue.6 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5
  • 107
    • 55949132020 scopus 로고    scopus 로고
    • Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: Potential for use as anovel nutraceutical for the treatment of osteoarthritis
    • Shakibaei, M.; Csaki, C.; Nebrich, S.; Mobasheri, A. Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: potential for use as anovel nutraceutical for the treatment of osteoarthritis. Biochem.Pharmacol. 2008, 76(11), 1426-1439.
    • (2008) Biochem.Pharmacol , vol.76 , Issue.11 , pp. 1426-1439
    • Shakibaei, M.1    Csaki, C.2    Nebrich, S.3    Mobasheri, A.4
  • 108
    • 33646068410 scopus 로고    scopus 로고
    • Resveratrolas a chemopreventive agent: A promising molecule forfighting cancer
    • Delmas, D.; Lancon, A.; Colin, D.; Jannin, B.; Latruffe, N. Resveratrolas a chemopreventive agent: a promising molecule forfighting cancer. Curr. Drug Targets 2006, 7(4), 423-442.
    • (2006) Curr. Drug Targets , vol.7 , Issue.4 , pp. 423-442
    • Delmas, D.1    Lancon, A.2    Colin, D.3    Jannin, B.4    Latruffe, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.