SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

Nature Genetics

Volumn 39, Issue 4, 2007, Pages 467-475

  Kitamura, Takanori ^a   Kometani, Kohei ^a   Hashida, Hiroki ^b   Matsunaga, Akihiro ^a   Miyoshi, Hiroyuki ^a   Hosogi, Hisahiro ^a   Aoki, Masahiro ^a   Oshima, Masanobu ^a,c   Hattori, Masakazu ^a   Takabayashi, Arimichi ^b   Minato, Nagahiro ^a   Taketo, Makoto M ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Kitano Hospital   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCL9 CHEMOKINE; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; GELATINASE A; GELATINASE B; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW CELL; CANCER INHIBITION; CANCER INVASION; CARCINOGENESIS; CD34 SELECTION; CELL MATURATION; CELLULAR DISTRIBUTION; COLORECTAL CANCER; CONTROLLED STUDY; EPITHELIUM; GENE DELETION; HUMAN; HUMAN TISSUE; INTESTINE TUMOR; MALE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD34; CARCINOMA; CELL MOVEMENT; FEMALE; INTESTINAL NEOPLASMS; MACROPHAGE INFLAMMATORY PROTEINS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELOID CELLS; NEOPLASM INVASIVENESS; RECEPTORS, CHEMOKINE; SMAD4 PROTEIN; STROMAL CELLS; TUMOR CELLS, CULTURED;

MUS;

EID: 34047138860     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1997     Document Type: Article

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