Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer

Biological Chemistry

Volumn 391, Issue 8, 2010, Pages 937-945

  Gocheva, Vasilena ^a,b   Chen, Xiaoping ^a   Peters, Christoph ^c   Reinheckel, Thomas ^c   Joyce, Johanna A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cancer; Cathepsin H; Mouse model; Pancreatic endocrine cancer; Protease

Indexed keywords

CATHEPSIN H; CD31 ANTIGEN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CANCER INVASION; CARCINOGENESIS; CLINICAL ASSESSMENT; CONFERENCE PAPER; GENE DELETION; GENE SWITCHING; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PANCREAS ISLET CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR VOLUME;

ANIMALS; APOPTOSIS; CATHEPSIN H; DISEASE PROGRESSION; GENE TARGETING; GTPASE-ACTIVATING PROTEINS; IMMUNOHISTOCHEMISTRY; INSULINOMA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; TUMOR BURDEN;

MUS;

EID: 77955964441     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.080     Document Type: Conference Paper

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