A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

Nature

Volumn 413, Issue 6853, 2001, Pages 323-327

  Malek, Nisar P ^a,b,c   Sundberg, Holly ^b,c   McGrew, Seth ^a,b   Nakayama, Keiko ^d   Kyriakidis, Themis R ^e   Roberts, James M ^a,b,e  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d KYUSHU UNIVERSITY   (Japan)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GENES; GENETIC ENGINEERING; TUMORS;

CELL CYCLE;

BIOCHEMISTRY;

CYCLIN DEPENDENT KINASE 2; PROTEIN P27; THREONINE;

MEDICINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; TRANSLATION REGULATION; WOUND HEALING;

ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; FEMALE; FIBROBLASTS; G1 PHASE; INTEGRASES; KERATINOCYTES; MALE; MICE; MICE, INBRED C57BL; MULTIENZYME COMPLEXES; MUTAGENESIS; PEPTIDE SYNTHASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; S PHASE; S-PHASE KINASE-ASSOCIATED PROTEINS; SKP CULLIN F-BOX PROTEIN LIGASES; THREONINE; TUMOR SUPPRESSOR PROTEINS; VIRAL PROTEINS; WOUND HEALING;

ANIMALIA; MURINAE; STAPHYLOCOCCUS PHAGE 187;

EID: 0035921821     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35095083     Document Type: Article

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