Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 4, 1997, Pages 1402-1407

  Wilson, Carole L ^a   Heppner, Kathleen J ^a   Labosky, Patricia A ^a,b   Hogan, Brigid L M ^a,b   Matrisian, Lynn M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

APC; colon cancer; extracellular matrix; knockout; Min

Indexed keywords

MATRILYSIN; METALLOPROTEINASE INHIBITOR;

ANIMAL MODEL; ARTICLE; CANCER INVASION; CARCINOGENESIS; COLON CANCER; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME LOCALIZATION; GENE TARGETING; GENETIC RECOMBINATION; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ANIMALS; CLONE CELLS; DISEASE MODELS, ANIMAL; GENES, APC; GENES, TUMOR SUPPRESSOR; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; STEM CELLS; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0031036359     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.4.1402     Document Type: Article

References (43)

1. MacDougall, J. R. & Matrisian, L. M. (1995) Cancer Metastasis Rev. 14, 351-362.
2. Powell, W. C. & Matrisian, L. M. (1996) in Attempts to Understand Metastasis Formation: I. Metastasis-Related Molecules, eds. Gunthert, W. & Birchmeier, W. (Springer, Heidelberg), pp. 1-22.
3. Wilson, C. L. & Matrisian, L. M. (1996) Int. J. Biochem. Cell Biol. 28, 123-136.
4. Saarialho-Kere, U.K., Crouch, E.G. & Parks, W. C. (1995) J. Invest. Dermatol. 105, 190-196.
5. Wilson, C. L., Heppner, K. J., Rudolph, L. A. & Matrisian, L. M. (1995) Mol. Biol. Cell 6, 851-869.
6. Heppner, K. J., Matrisian, L. M., Jensen, R. A. & Rodgers, W. H. (1996) Am. J. Pathol. 149, 273-282.
7. Wolf, C., Rouyer, N., Lutz, Y., Adida, C., Loriot, M., Bellocq, J.-P., Chambon, P. & Basset, P. (1993) Proc. Natl. Acad. Sci. USA 90, 1843-1847.
8. McDonnell, S., Navre, M., Coffey, R. J. & Matrisian, L. M. (1991) Mol. Carcinog. 4, 527-533.
9. Newell, K. J., Witty, J. P., Rodgers, W. H. & Matrisian, L. M. (1994) Mol. Carcinog. 10, 199-206.
10. Yoshimoto, M., Itoh, F., Yamamoto, H., Hinoda, Y., Imai, K. & Yachi, K. (1993) Int. J. Cancer 54, 614-618.
11. Yamamoto, H., Itoh, F., Hinoda, Y., Senota, A., Yoshimoto, M., Nakamura, H., Imai, K. & Yachi, A. (1994) Biochem. Biophys. Res. Commun. 201, 657-664.
12. Witty, J. P., McDonnell, S., Newell, K., Cannon, P., Navre, M., Tressler, R. & Matrisian, L. M. (1994) Cancer Res. 54, 4805-4812.
13. Moser, A. R., Pitot, H. C. & Dove, W. F. (1990) Science 247, 322-324.
14. Su, L., Kinzler, K. W., Vogelstein, B., Preisinger, A. C., Moser, A. R., Luongo, C., Gould, K. A. & Dove, W. F. (1992) Science 256, 668-670.
15. Dietrich, W. F., Lander, E. S., Smith, J. S., Moser, A. R., Gould, K. A., Luongo, C., Borenstein, N. & Dove, W. (1993) Cell 75, 631-639.
16. Witty, J. P., Wright, J. & Matrisian, L. M. (1995) Mol. Biol. Cell 6, 1287-1303.
17. Guan, K.-L. & Dixon, J. E. (1991) Anal. Biochem. 192, 262-267.
18. Harlow, E. & Lane, D. (1988) Antibodies: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY), pp. 283-318.
19. Rowe, L. B., Nadeau, J. G., Turner, R., Frankel, W. N., Letts, V. A., Eppig, J. T., Ko, M. S. H., Thurston, S. J. & Birkenmeier, E. H. (1994) Mamm. Genome 5, 253-274.
20. Rudnicki, M. A., Braun, T., Hinuma, S. & Jaenisch, R. (1992) Cell 71, 383-390.
21. Mansour, S. L., Thomas, K. R. & Capecchi, M. R. (1988) Nature (London) 336, 348-352.
22. Hogan, B., Beddington, R., Costantini, F. & Lacy, E. (1995) Manipulating the Mouse Embryo: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY), Vol. 2, pp. 217-253.
23. Chomczynski, P. & Sacchi, N. (1987) Anal. Biochem. 162, 156-159.
24. Shapiro, S. D., Griffin, G. L., Gilbert, D. J., Jenkins, N. A., Copeland, N. G., Welgus, H. G., Senior, R. M. & Ley, T. J. (1992) J. Biol. Chem. 267, 4664-4671.
25. Schorpp, M., Mattei, M., Herr, I., Gack, S., Schaper, J. & Angel, P. (1995) Biochem. J. 308, 211-217.
26. Ouellette, A. J., Greco, R. M., James, M., Frederick, D., Naftilan, J. & Fallon, J. T. (1989) J. Cell Biol. 108, 1687-1695.
27. Laird, P. W., Jackson-Grusby, L., Fazeli, A., Dickinson, S. L., Jung, W. E., Li, E., Weinberg, R. A. & Jaenisch, R. (1995) Cell 81, 197-205.
28. MacPhee, M., Chepenik, K. P., Liddell, R. A., Nelson, K. K., Siracusa, L. D. & Buchberg, A. M. (1995) Cell 81, 957-966.
29. Fearon, E. R. & Vogelstein, B. (1990) Cell 61, 759-767.
30. Kim, S. H., Roth, K. A., Moser, A. R. & Gordon, J. I. (1993) J. Cell Biol. 123, 877-893.
31. Dove, W. F., Luongo, C., Connelly, C. S., Gould, K. A., Shoemaker, A. R., Moser, A. R. & Gardner, R. L. (1994) Cold Spring Harbor Symp. Quant. Biol. 59, 501-508.
32. Clarke, A. R., Cummings, M. C. & Harrison, D. J. (1995) Oncogene 11, 1913-1920.
33. Jacoby, R. F., Marshall, D. J., Newton, M. A., Novakovic, K., Tutsch, K., Cole, C. E., Lubet, R. A., Kelloff, G. J., Verma, A., Moser, A. R. & Dove, W. F. (1996) Cancer Res. 56, 710-714.
34. Kennedy, A. R., Beazer-Barclay, Y., Kinzler, K. W. & Newberne, P. M. (1996) Cancer Res. 56, 679-682.
35. Boudreau, N., Sympson, C. J., Werb, Z. & Bissell, M. J. (1995) Science 267, 891-893.
36. Sympson, C. J., Talhouk, R. S., Alexander, C. M., Chin, J. R., Clift, S. M., Bissell, M. J. & Werb, Z. (1994) J. Cell Biol. 125, 681-693.
37. Witty, J. P., Lempka, T., Coffey, R. J., Jr., & Matrisian, L. M. (1995) Cancer Res. 55, 1401-1406.
38. Gearing, A. J. H., Beckett, P., Christodoulou, M., Churchill, M., Clements, J., et al. (1994) Nature (London) 370, 555-557.
39. Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., Inoue, S., Yoshino, K., Okumura, K. & Yagita, H. (1995) J. Exp. Med. 182, 1777-1783.
40. Lanzrein, M., Garred, O., Olsnes, S. & Sandvig, K. (1995) Biochem. J. 310, 285-289.
41. Powell, S. M., Zilz, N., Beazer-Barclay, Y., Bryan, T. M., Hamilton, S. R., Thibodeau, S. N., Vogelstein, B. & Kinzler, K. W. (1992) Nature (London) 359, 235-237.
42. Watson, S. A., Morris, T. M., Robinson, G., Crimmin, M. J., Brown, P. D. & Hardcastle, J. D. (1995) Cancer Res. 55, 3629-3633.
43. Wang, X., Fu, X., Brown, P. D., Crimmin, M. J. & Hoffman, R. M. (1994) Cancer Res. 54, 4726-4728.