Retraction: Retraction (British Journal of Pharmacology, (2013), 169, 3, (717), 10.1002/mc.23342);Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin-mediated cell adhesion and invasion in glioma

Molecular Carcinogenesis

Volumn 52, Issue 10, 2013, Pages 777-790

  Rao Malla, Rama ^a   Gopinath, Sreelatha ^a   Alapati, Kiranmai ^a   Gorantla, Bharathi ^a   Gondi, Christopher S ^a   Rao, Jasti S ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Adhesion; CD151; Integrin; Laminin

Indexed keywords

ACTIN BINDING PROTEIN; CATHEPSIN B; CD151 ANTIGEN; COLLAGEN TYPE 1; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; KALININ; PAXILLIN; SMALL INTERFERING RNA; TALIN; UROKINASE RECEPTOR; VERY LATE ACTIVATION ANTIGEN 3; VINCULIN; VITRONECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TISSUE MICROARRAY;

MUS MUSCULUS;

EID: 84884816982     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.23342     Document Type: Erratum

References (43)

1. Fukushima Y, Ohnishi T, Arita N, Hayakawa T, Sekiguchi K. Integrin alpha3beta1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells. Int J Cancer 1998; 76:63-72.
2. Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS. RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas. Oncogene 2004; 23:8486-8496.
3. Bass R, Werner F, Odintsova E, Sugiura T, Berditchevski F, Ellis V. Regulation of urokinase receptor proteolytic function by the tetraspanin CD82. J Biol Chem 2005; 280:14811-14818.
4. Resnati M, Pallavicini I, Wang JM, et al. The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. Proc Natl Acad Sci USA 2002; 99:1359-1364.
5. Wei Y, Eble JA, Wang Z, Kreidberg JA, Chapman HA. Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1. Mol Biol Cell 2001; 12:2975-2986.
6. Rao JS. Molecular mechanisms of glioma invasiveness: The role of proteases. Nat Rev Cancer 2003; 3:489-501.
7. Stipp CS, Kolesnikova TV, Hemler ME. Functional domains in tetraspanin proteins. Trends Biochem Sci 2003; 28:106-112.
8. Hemler ME. Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain. Annu Rev Cell Dev Biol 2003; 19:397-422, 397-422.
9. Bredel M, Bredel C, Juric D, et al. Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res 2005; 65:8679-8689.
10. Yang J, Liu Z, Shen X, et al. Expression of CD151 in human atherosclerotic artery and its implication. J Huazhong Univ Sci Technol Med Sci 2005; 25:629-631.
11. Critchley DR. Focal adhesions-The cytoskeletal connection. Curr Opin Cell Biol 2000; 12:133-139.
12. Bois PR, O'Hara BP, Nietlispach D, Kirkpatrick J, Izard T. The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin. J Biol Chem 2006; 281:7228-7236.
13. Bass MD, Smith BJ, Prigent SA, Critchley DR. Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix. Biochem J 1999; 341:257-263.
14. Tarui T, Andronicos N, Czekay RP, et al. Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR CD87) signaling. J Biol Chem 2003; 278:29863-29872.
15. Gondi CS, Kandhukuri N, Kondraganti S, et al. Down-regulation of uPAR and cathepsin B retards cofilin dephosphorylation. Int J Oncol 2006; 28:633-639.
16. Veeravalli KK, Chetty C, Ponnala S, et al. MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice. PLoS One 2010; 5:e11583.
17. Albini A, Iwamoto Y, Kleinman HK, et al. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 1987; 47:3239-3245.
18. Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS. Intraperitoneal injection of an hpRNA-expressing plasmid targeting uPAR and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Clin Cancer Res 2007; 13:4051-4060.
19. Lakka SS, Gondi CS, Yanamandra N, et al. Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene 2004; 23:4681-4689.
20. Gopinath S, Malla RR, Gondi CS, et al. Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation. PLoS One 2010; 5:e11668.
21. Malla R, Gopinath S, Alapati K, et al. Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas. PLoS One 2010; 5:e13731.
22. Chapman HA, Wei Y. Protease crosstalk with integrins: The urokinase receptor paradigm. Thromb Haemost 2001; 86:124-129.
23. Ossowski L, Aguirre-Ghiso JA. Urokinase receptor and integrin partnership: Coordination of signaling for cell adhesion, migration and growth. Curr Opin Cell Biol 2000; 12:613-620.
24. Chintala SK, Mohanam S, Go Y, et al. Altered in vitro spreading and cytoskeletal organization in human glioma cells by downregulation of urokinase receptor. Mol Carcinog 1997; 20:355-365.
25. Natarajan M, Hecker TP, Gladson CL. FAK signaling in anaplastic astrocytoma and glioblastoma tumors. Cancer J 2003; 9:126-133.
26. Nowicki TS, Zhao H, Darzynkiewicz Z, et al. Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells. Cell Cycle 2011; 10:100-107.
27. Goldbrunner RH, Bernstein JJ, Tonn JC. ECM-mediated glioma cell invasion. Microsc Res Tech 1998; 43:250-257.
28. Lah TT, Buck MR, Honn KV, et al. Degradation of laminin by human tumor cathepsin B. Clin Exp Metastasis 1989; 7:461-468.
29. Smith HW, Marshall CJ. Regulation of cell signalling by uPAR. Nat Rev Mol Cell Biol 2010; 11:23-36.
30. Yang XH, Flores LM, Li Q, et al. Disruption of laminin-integrin-CD151-focal adhesion kinase axis sensitizes breast cancer cells to ErbB2 antagonists. Cancer Res 2010; 70:2256-2263.
31. Nalla AK, Gorantla B, Gondi CS, Lakka SS, Rao JS. Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells. Cancer Gene Ther 2010; 17:599-613.
32. Malla RR, Gopinath S, Gondi CS, et al. Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma. Cancer Gene Ther 2011; 18:419-434.
33. Kohno M, Hasegawa H, Miyake M, Yamamoto T, Fujita S. CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int J Cancer 2002; 97:336-343.
34. Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L. ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK). Cancer Res 2003; 63:1684-1695.
35. Hebrok M, Reichardt LF. Brain meets pancreas: Netrin, an axon guidance molecule, controls epithelial cell migration. Trends Cell Biol 2004; 14:153-155.
36. Abu-Ali S, Sugiura T, Takahashi M, et al. Expression of the urokinase receptor regulates focal adhesion assembly and cell migration in adenoid cystic carcinoma cells. J Cell Physiol 2005; 203:410-419.
37. Gupta R, Nalla AK, Gogineni VR, et al. uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma. PLoS One 2011; 6:e17123.
38. Nalla AK, Asuthkar S, Bhoopathi P, Gujrati M, Dinh DH, Rao JS. Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin beta1/FAK signaling in medulloblastoma. PLoS One 2010; 5:e13006.
39. Aguirre-Ghiso JA. Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo. Oncogene 2002; 21:2513-2524.
40. Shi Q, Boettiger D. A novel mode for integrin-mediated signaling: Tethering is required for phosphorylation of FAK Y397. Mol Biol Cell 2003; 14:4306-4315.
41. Ke AW, Shi GM, Zhou J, et al. Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma. Hepatology 2009; 49:491-503.
42. Yang XH, Richardson AL, Torres-Arzayus MI, et al. CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization. Cancer Res 2008; 68:3204-3213.
43. Zijlstra A, Lewis J, Degryse B, Stuhlmann H, Quigley JP. The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell 2008; 13:221-234.