메뉴 건너뛰기




Volumn 5, Issue 5, 2004, Pages 417-421

The development of proteasome inhibitors as anticancer drugs

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB;

EID: 2342667387     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(04)00120-5     Document Type: Review
Times cited : (715)

References (52)
  • 1
    • 0036181371 scopus 로고    scopus 로고
    • Development of the proteasome inhibitor PS-341
    • a
    • Adams J. Development of the proteasome inhibitor PS-341. Oncologist. 7:2002;9-16. a
    • (2002) Oncologist , vol.7 , pp. 9-16
    • Adams, J.1
  • 2
    • 0036217332 scopus 로고    scopus 로고
    • Proteasome inhibition: A novel approach to cancer therapy
    • b
    • Adams J. Proteasome inhibition. A novel approach to cancer therapy Trends Mol. Med. 8(suppl 4):2002;S49-S54. b
    • (2002) Trends Mol. Med. , vol.8 , Issue.SUPPL. 4
    • Adams, J.1
  • 3
    • 0037852202 scopus 로고    scopus 로고
    • The proteasome: Structure, function, and role in the cell
    • Adams J. The proteasome. Structure, function, and role in the cell Cancer Treat. Rev. 29(suppl 1):2003;3-9
    • (2003) Cancer Treat. Rev. , vol.29 , Issue.SUPPL. 1 , pp. 3-9
    • Adams, J.1
  • 4
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome. A suitable antineoplastic target Nat. Rev. Cancer. 4:2004;349-360
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 7
    • 0034062989 scopus 로고    scopus 로고
    • Proteasome inhibition: A new strategy in cancer treatment
    • Adams J., Palombella V.J., Elliott P.J. Proteasome inhibition. A new strategy in cancer treatment Invest. New Drugs. 18:2000;109-121
    • (2000) Invest. New Drugs , vol.18 , pp. 109-121
    • Adams, J.1    Palombella, V.J.2    Elliott, P.J.3
  • 10
    • 0036240701 scopus 로고    scopus 로고
    • The proteasome: A novel target for cancer chemotherapy
    • Almond J.B., Cohen G.M. The proteasome. A novel target for cancer chemotherapy Leukemia. 16:2002;433-443
    • (2002) Leukemia , vol.16 , pp. 433-443
    • Almond, J.B.1    Cohen, G.M.2
  • 11
    • 0032429122 scopus 로고    scopus 로고
    • Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
    • An B., Goldfarb R.H., Siman R., Dou Q.P. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ. 5:1998;1062-1075
    • (1998) Cell Death Differ. , vol.5 , pp. 1062-1075
    • An, B.1    Goldfarb, R.H.2    Siman, R.3    Dou, Q.P.4
  • 13
    • 18244428600 scopus 로고    scopus 로고
    • For the Myeloma Subcommittee of the European Group for Blood and Marrow Transplant. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
    • Bladé J., Samson D., Reece D., Apperley J., Bjorkstrand B., Gahrton G., Gertz M., Giralt S., Jagannath S., Vesole D. for the Myeloma Subcommittee of the European Group for Blood and Marrow Transplant. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Br. J. Haematol. 102:1998;1115-1123
    • (1998) Br. J. Haematol. , vol.102 , pp. 1115-1123
    • Bladé, J.1    Samson, D.2    Reece, D.3    Apperley, J.4    Bjorkstrand, B.5    Gahrton, G.6    Gertz, M.7    Giralt, S.8    Jagannath, S.9    Vesole, D.10
  • 14
    • 0034875305 scopus 로고    scopus 로고
    • Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome
    • Bold R.J., Virudachalam S., McConkey D.J. Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. J. Surg. Res. 100:2001;11-17
    • (2001) J. Surg. Res. , vol.100 , pp. 11-17
    • Bold, R.J.1    Virudachalam, S.2    McConkey, D.J.3
  • 15
    • 0035328584 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-κB inhibition
    • Cusack J.C. Jr., Liu R., Houston M., Abendroth K., Elliott P.J., Adams J., Baldwin S.S. Jr. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341. Implications for systemic nuclear factor-κB inhibition Cancer Res. 61:2001;3535-3540
    • (2001) Cancer Res. , vol.61 , pp. 3535-3540
    • Cusack Jr., J.C.1    Liu, R.2    Houston, M.3    Abendroth, K.4    Elliott, P.J.5    Adams, J.6    Baldwin Jr., S.S.7
  • 16
    • 0035422206 scopus 로고    scopus 로고
    • Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells
    • Desai S.D., Li T.K., Rodriguez-Bauman A., Rubin E.H., Liu L.F. Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells. Cancer Res. 61:2001;5926-5932
    • (2001) Cancer Res. , vol.61 , pp. 5926-5932
    • Desai, S.D.1    Li, T.K.2    Rodriguez-Bauman, A.3    Rubin, E.H.4    Liu, L.F.5
  • 17
    • 0031034160 scopus 로고    scopus 로고
    • Activation of the cell death program by inhibition of proteasome function
    • Drexler H.C. Activation of the cell death program by inhibition of proteasome function. Proc. Natl. Acad. Sci. USA. 94:1997;855-860
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 855-860
    • Drexler, H.C.1
  • 18
    • 0033965742 scopus 로고    scopus 로고
    • Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells
    • Drexler H.C.A., Risau W., Konerding M.A. Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells. FASEB J. 14:2000;65-77
    • (2000) FASEB J. , vol.14 , pp. 65-77
    • Drexler, H.C.A.1    Risau, W.2    Konerding, M.A.3
  • 19
    • 0033817518 scopus 로고    scopus 로고
    • Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341
    • Frankel A., Man S., Elliott P., Adams J., Kerbel R.S. Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341. Clin. Cancer Res. 6:2000;3719-3728
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3719-3728
    • Frankel, A.1    Man, S.2    Elliott, P.3    Adams, J.4    Kerbel, R.S.5
  • 20
    • 1842645976 scopus 로고    scopus 로고
    • Report of a phase II study of proteasome inhibitor bortezomib (VELCADE™) in patients with relapsed or refractory indolent or aggressive lymphomas
    • Goy A., Hart S., Pro B., McLaughlin P., Younes A., Dang N., Fayad L., Romaguera J., Cabanillas F., Hagemeister F., et al. Report of a phase II study of proteasome inhibitor bortezomib (VELCADE™) in patients with relapsed or refractory indolent or aggressive lymphomas. Blood. 102:2003;180a
    • (2003) Blood , vol.102
    • Goy, A.1    Hart, S.2    Pro, B.3    McLaughlin, P.4    Younes, A.5    Dang, N.6    Fayad, L.7    Romaguera, J.8    Cabanillas, F.9    Hagemeister, F.10
  • 22
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T., Richardson P., Chauhan D., Palombella V.J., Elliott P.J., Adams J., Anderson K.C. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 61:2001;3071-3076
    • (2001) Cancer Res. , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3    Palombella, V.J.4    Elliott, P.J.5    Adams, J.6    Anderson, K.C.7
  • 24
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: From innocent bystander to major culprit
    • Karin M., Cao Y., Greten F.R., Li Z.W. NF-κB in cancer. From innocent bystander to major culprit Nat. Rev. Cancer. 2:2002;301-310
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 25
    • 0021723091 scopus 로고
    • Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids
    • Kettner C.A., Shenvi A.B. Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids. J. Biol. Chem. 259:1984;15106-15114
    • (1984) J. Biol. Chem. , vol.259 , pp. 15106-15114
    • Kettner, C.A.1    Shenvi, A.B.2
  • 27
    • 0034864799 scopus 로고    scopus 로고
    • Proteasome inhibitors: From research tools to drug candidates
    • Kisselev A.F., Goldberg A.L. Proteasome inhibitors. From research tools to drug candidates Chem. Biol. 8:2001;739-758
    • (2001) Chem. Biol. , vol.8 , pp. 739-758
    • Kisselev, A.F.1    Goldberg, A.L.2
  • 30
    • 0034635952 scopus 로고    scopus 로고
    • Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
    • Li B., Dou Q.P. Bax degradation by the ubiquitin/proteasome-dependent pathway. Involvement in tumor survival and progression Proc. Natl. Acad. Sci. USA. 97:2000;3850-3855
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3850-3855
    • Li, B.1    Dou, Q.P.2
  • 31
    • 0037342895 scopus 로고    scopus 로고
    • Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines
    • Ling Y.H., Liebes L., Jiang J.D., Holland J.F., Elliott P.J., Adams J., Muggia F.M., Perez-Soler R. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. Clin. Cancer Res. 9:2003;1145-1154
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1145-1154
    • Ling, Y.H.1    Liebes, L.2    Jiang, J.D.3    Holland, J.F.4    Elliott, P.J.5    Adams, J.6    Muggia, F.M.7    Perez-Soler, R.8
  • 33
    • 0035072563 scopus 로고    scopus 로고
    • P53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells
    • MacLaren A.P., Chapman R.S., Wyllie A.H., Watson C.J. p53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells. Cell Death Differ. 8:2001;210-218
    • (2001) Cell Death Differ. , vol.8 , pp. 210-218
    • MacLaren, A.P.1    Chapman, R.S.2    Wyllie, A.H.3    Watson, C.J.4
  • 34
    • 0343932632 scopus 로고    scopus 로고
    • Deregulation of the ubiquitin system an dp53 proteolysis modify the apoptotic response in B-CLL lymphocytes
    • Masdehors P., Merle-Béral H., Maloum K., Omura S., Magdelénat H., Delic J. Deregulation of the ubiquitin system an dp53 proteolysis modify the apoptotic response in B-CLL lymphocytes. Blood. 96:2000;269-274
    • (2000) Blood , vol.96 , pp. 269-274
    • Masdehors, P.1    Merle-Béral, H.2    Maloum, K.3    Omura, S.4    Magdelénat, H.5    Delic, J.6
  • 35
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • Mitsiades N., Mitsiades C.S., Richardson P.G., Poulaki V., Tai Y.-T., Chauhan D., Fanourakis G., Gu X., Bailey C., Joseph M., et al. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents. therapeutic applications Blood. 101:2003;2377-2380
    • (2003) Blood , vol.101 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3    Poulaki, V.4    Tai, Y.-T.5    Chauhan, D.6    Fanourakis, G.7    Gu, X.8    Bailey, C.9    Joseph, M.10
  • 38
    • 0034193276 scopus 로고    scopus 로고
    • Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs
    • Ogiso Y., Tomida A., Lei S., Omura S., Tsuro T. Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs. Cancer Res. 60:2000;2429-2434
    • (2000) Cancer Res. , vol.60 , pp. 2429-2434
    • Ogiso, Y.1    Tomida, A.2    Lei, S.3    Omura, S.4    Tsuro, T.5
  • 39
    • 0032189685 scopus 로고    scopus 로고
    • Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
    • Orlowski R.Z., Eswara J.R., Lafond-Walker A., Grever M.R., Orlowski M., Dang C.V. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res. 58:1998;4342-4348
    • (1998) Cancer Res. , vol.58 , pp. 4342-4348
    • Orlowski, R.Z.1    Eswara, J.R.2    Lafond-Walker, A.3    Grever, M.R.4    Orlowski, M.5    Dang, C.V.6
  • 41
    • 0034237661 scopus 로고    scopus 로고
    • Apoptosis and radiosensitization of hodgkin cells by proteasome inhibition
    • Pajonk F., Pajonk K., McBride W.H. Apoptosis and radiosensitization of hodgkin cells by proteasome inhibition. Int. J. Radiat. Oncol. Biol. Phys. 47:2000;1025-1032
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.47 , pp. 1025-1032
    • Pajonk, F.1    Pajonk, K.2    McBride, W.H.3
  • 42
    • 0038206722 scopus 로고    scopus 로고
    • Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
    • Pham L.V., Tamayo A.T., Yoshimura L.C., Lo P., Ford R.J. Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J. Immunol. 171:2003;88-95
    • (2003) J. Immunol. , vol.171 , pp. 88-95
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lo, P.4    Ford, R.J.5
  • 46
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-κB, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo J.B., Chen Z., Dong G., Yeh N., Bancroft C.C., Sausville E., Adams J., Elliott P., Van Waes C. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-κB, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin. Cancer Res. 7:2001;1419-1428
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1419-1428
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3    Yeh, N.4    Bancroft, C.C.5    Sausville, E.6    Adams, J.7    Elliott, P.8    Van Waes, C.9
  • 47
    • 0036172154 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341, a potential therapeutic agent for adult T-cell leukemia
    • Tan C., Waldmann T.A. Proteasome inhibitor PS-341, a potential therapeutic agent for adult T-cell leukemia. Cancer Res. 62:2002;1083-1086
    • (2002) Cancer Res. , vol.62 , pp. 1083-1086
    • Tan, C.1    Waldmann, T.A.2
  • 49
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kB
    • Wang C.Y., Cusack J.C. Jr., Liu R., Baldwin A.S. Jr. Control of inducible chemoresistance. Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kB Nat. Med. 5:1999;412-417
    • (1999) Nat. Med. , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack Jr., J.C.2    Liu, R.3    Baldwin Jr., A.S.4
  • 50
    • 0028930160 scopus 로고
    • Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs
    • Weber P.C., Lee S.L., Lewandowski F.A., Schadt M.C., Chang C.W., Kettner C.A. Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro- boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. Biochemistry. 34:1995;3750-3757
    • (1995) Biochemistry , vol.34 , pp. 3750-3757
    • Weber, P.C.1    Lee, S.L.2    Lewandowski, F.A.3    Schadt, M.C.4    Chang, C.W.5    Kettner, C.A.6
  • 51
    • 0642349188 scopus 로고    scopus 로고
    • Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts
    • Williams S., Pettaway C., Song R., Papandreou C., Logothetis C., McConkey D.J. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol. Cancer Ther. 2:2003;835-843
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 835-843
    • Williams, S.1    Pettaway, C.2    Song, R.3    Papandreou, C.4    Logothetis, C.5    McConkey, D.J.6
  • 52
    • 1942534018 scopus 로고    scopus 로고
    • Regulation of apoptosis proteins in cancer cells by ubiquitin
    • Zhang H.G., Wang J., Yang X., Hsu H.C., Mountz J.D. Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene. 23:2004;2009-2015
    • (2004) Oncogene , vol.23 , pp. 2009-2015
    • Zhang, H.G.1    Wang, J.2    Yang, X.3    Hsu, H.C.4    Mountz, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.