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Volumn 10, Issue 5, 1998, Pages 667-671

Cancer invasion and tissue remodeling: Common themes in proteolytic matrix degradation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; BREAST CANCER; BREAST DISEASE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CELL INTERACTION; CELL TYPE; COLON CANCER; EXTRACELLULAR MATRIX; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; REVIEW; SQUAMOUS CELL CARCINOMA; STROMA CELL; WOUND HEALING;

EID: 0031719897     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(98)80044-6     Document Type: Article
Times cited : (331)

References (44)
  • 1
    • 0027994264 scopus 로고
    • The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion
    • Danø K, Behrendt N, Brünner N, Ellis V, Ploug M, Pyke C. The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion. Fibrinolysis. 8:1994;189-203.
    • (1994) Fibrinolysis , vol.8 , pp. 189-203
    • Danø, K.1    Behrendt, N.2    Brünner, N.3    Ellis, V.4    Ploug, M.5    Pyke, C.6
  • 3
    • 0003014288 scopus 로고
    • The receptor for urokinase plasminogen activator. Stromal cell involvement in extracellular proteolysis during cancer invasion
    • A.J. Barrett, Bond J. London: Portland Press
    • Danø K, Grøndahl-Hansen J, Eriksen J, Nielsen BS, Rømer J, Pyke C. The receptor for urokinase plasminogen activator. Stromal cell involvement in extracellular proteolysis during cancer invasion. Barrett AJ, Bond J. Proteolysis and Protein Turnover. 1993;239-245 Portland Press, London.
    • (1993) Proteolysis and Protein Turnover , pp. 239-245
    • Danø, K.1    Grøndahl-Hansen, J.2    Eriksen, J.3    Nielsen, B.S.4    Rømer, J.5    Pyke, C.6
  • 4
    • 0029944555 scopus 로고    scopus 로고
    • Differential expression of urokinase-type plasminogen activator, its receptor, and inhibitors in mouse skin after exposure to a tumor-promoting phorbol ester
    • Lund LR, Eriksen J, Ralfkiær E, Rømer J. Differential expression of urokinase-type plasminogen activator, its receptor, and inhibitors in mouse skin after exposure to a tumor-promoting phorbol ester. J Invest Dermatol. 106:1996;622-630.
    • (1996) J Invest Dermatol , vol.106 , pp. 622-630
    • Lund, L.R.1    Eriksen, J.2    Ralfkiær, E.3    Rømer, J.4
  • 5
    • 0023946446 scopus 로고
    • Urokinase- And tissue-type plasminogen activators in keratinocytes during wound reepithelization in vivo
    • Grøndahl-Hansen J, Lund LR, Ralfkiær E, Ottevanger V, Danø K. Urokinase- and tissue-type plasminogen activators in keratinocytes during wound reepithelization in vivo. J Invest Dermatol. 90:1988;790-795.
    • (1988) J Invest Dermatol , vol.90 , pp. 790-795
    • Grøndahl-Hansen, J.1    Lund, L.R.2    Ralfkiær, E.3    Ottevanger, V.4    Danø, K.5
  • 6
    • 0028327420 scopus 로고
    • The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds
    • Rømer J, Lund LR, Eriksen J, Pyke C, Kristensen P, Danø K. The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds. J Invest Dermatol. 102:1994;519-522.
    • (1994) J Invest Dermatol , vol.102 , pp. 519-522
    • Rømer, J.1    Lund, L.R.2    Eriksen, J.3    Pyke, C.4    Kristensen, P.5    Danø, K.6
  • 8
    • 0028920904 scopus 로고
    • Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction
    • Bugge TH, Flick MJ, Daugherty CC, Degen JL. Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction. Genes Dev. 9:1995;794-807.
    • (1995) Genes Dev , vol.9 , pp. 794-807
    • Bugge, T.H.1    Flick, M.J.2    Daugherty, C.C.3    Degen, J.L.4
  • 12
    • 0026589277 scopus 로고
    • Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization
    • Pyke C, Ralfkiær E, Huhtala P, Hurskainen T, Danø K, Tryggvason K. Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization. Cancer Res. 52:1992;1336-1341.
    • (1992) Cancer Res , vol.52 , pp. 1336-1341
    • Pyke, C.1    Ralfkiær, E.2    Huhtala, P.3    Hurskainen, T.4    Danø, K.5    Tryggvason, K.6
  • 15
    • 0027076036 scopus 로고
    • Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: A review
    • Basset P, Wolf C, Chambon P. Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review. Breast Cancer Res Treat. 24:1993;185-193.
    • (1993) Breast Cancer Res Treat , vol.24 , pp. 185-193
    • Basset, P.1    Wolf, C.2    Chambon, P.3
  • 16
    • 0029682495 scopus 로고    scopus 로고
    • Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: Cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals
    • Shapiro RL, Duquette JG, Roses DF, Nunes I, Harris MN, Kamino H, Wilson EL, Rifkin DB. Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals. Cancer Res. 56:1996;3597-3604.
    • (1996) Cancer Res , vol.56 , pp. 3597-3604
    • Shapiro, R.L.1    Duquette, J.G.2    Roses, D.F.3    Nunes, I.4    Harris, M.N.5    Kamino, H.6    Wilson, E.L.7    Rifkin, D.B.8
  • 17
    • 0030739571 scopus 로고    scopus 로고
    • Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis
    • of outstanding interest. This paper shows that lack of plasminogen activity in humans is compatible with fetal development and at least childhood life. After the publication of this paper, the clinical manifestation ligneous conjunctivitis was also found in plasminogen-deficient mice (Drew AF: Ligneous conjunctivitis in plasminogen-deficient mice. Blood 1998, 91:1616-1624).
    • Schuster V, Mingers AM, Seidenspinner S, Nussgens Z, Pukrop T, Kreth HW. Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis. of outstanding interest Blood. 90:1997;958-966 This paper shows that lack of plasminogen activity in humans is compatible with fetal development and at least childhood life. After the publication of this paper, the clinical manifestation ligneous conjunctivitis was also found in plasminogen-deficient mice (Drew AF: Ligneous conjunctivitis in plasminogen-deficient mice. Blood 1998, 91:1616-1624).
    • (1997) Blood , vol.90 , pp. 958-966
    • Schuster, V.1    Mingers, A.M.2    Seidenspinner, S.3    Nussgens, Z.4    Pukrop, T.5    Kreth, H.W.6
  • 21
    • 0030061754 scopus 로고    scopus 로고
    • Messenger RNA for urokinase plasminogen activator is expressed in myofibroblasts adjacent to cancer cells in human breast cancer
    • Nielsen BS, Sehested M, Timshel S, Pyke C, Danø K. Messenger RNA for urokinase plasminogen activator is expressed in myofibroblasts adjacent to cancer cells in human breast cancer. Lab Invest. 74:1996;168-177.
    • (1996) Lab Invest , vol.74 , pp. 168-177
    • Nielsen, B.S.1    Sehested, M.2    Timshel, S.3    Pyke, C.4    Danø, K.5
  • 22
    • 0029946569 scopus 로고    scopus 로고
    • Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response
    • Heppner KJ, Matrisian LM, Jensen RA, Rodgers WH. Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am J Pathol. 149:1996;273-282.
    • (1996) Am J Pathol , vol.149 , pp. 273-282
    • Heppner, K.J.1    Matrisian, L.M.2    Jensen, R.A.3    Rodgers, W.H.4
  • 23
    • 0027534904 scopus 로고
    • Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression
    • Wolf C, Rouyer N, Lutz Y, Adida C, Loriot M, Bellocq JP, Chambon P, Basset P. Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc Natl Acad Sci USA. 90:1993;1843-1847.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1843-1847
    • Wolf, C.1    Rouyer, N.2    Lutz, Y.3    Adida, C.4    Loriot, M.5    Bellocq, J.P.6    Chambon, P.7    Basset, P.8
  • 24
    • 0030661882 scopus 로고    scopus 로고
    • Expression of the matrix metalloprotease-9 in vascular pericytes in human breast cancer
    • Nielsen BS, Sehested M, Kjeldsen L, Borregaard N, Danø K. Expression of the matrix metalloprotease-9 in vascular pericytes in human breast cancer. Lab Invest. 77:1997;345-355.
    • (1997) Lab Invest , vol.77 , pp. 345-355
    • Nielsen, B.S.1    Sehested, M.2    Kjeldsen, L.3    Borregaard, N.4    Danø, K.5
  • 25
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
    • Guy CT, Cardiff RD, Muller WJ. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol. 12:1992;954-961.
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 26
    • 7344248988 scopus 로고    scopus 로고
    • Reduced metastasis of mammary cancer in plasminogen-deficient mice
    • of outstanding interest. This is the first study that shows that plasminogen has an important function in metastasis. The tumor spread from a primary tumor of genetic origin is significantly delayed in plasminogen-deficient mice. In this tumor model, as in human ductal breast carinomas, urokinase plasminogen activator (uPA) is synthesized by stromal cells.
    • Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmbäck K, Drew AF, Flick MJ, Witte DP, Danø K, Degen JL. Reduced metastasis of mammary cancer in plasminogen-deficient mice. of outstanding interest Oncogene. 16:1998;3097-3104 This is the first study that shows that plasminogen has an important function in metastasis. The tumor spread from a primary tumor of genetic origin is significantly delayed in plasminogen-deficient mice. In this tumor model, as in human ductal breast carinomas, urokinase plasminogen activator (uPA) is synthesized by stromal cells.
    • (1998) Oncogene , vol.16 , pp. 3097-3104
    • Bugge, T.H.1    Lund, L.R.2    Kombrinck, K.K.3    Nielsen, B.S.4    Holmbäck, K.5    Drew, A.F.6    Flick, M.J.7    Witte, D.P.8    Danø, K.9    Degen, J.L.10
  • 28
    • 0029312344 scopus 로고
    • Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1
    • Sympson CJ, Bissell MJ, Werb Z. Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1. Semin Cancer Biol. 6:1995;159-163.
    • (1995) Semin Cancer Biol , vol.6 , pp. 159-163
    • Sympson, C.J.1    Bissell, M.J.2    Werb, Z.3
  • 29
    • 0030839472 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition as a novel anticancer strategy: A review with special focus on batimastat and marimastat
    • Rasmussen HS, McCann PP. Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacol Ther. 75:1997;69-75.
    • (1997) Pharmacol Ther , vol.75 , pp. 69-75
    • Rasmussen, H.S.1    McCann, P.P.2
  • 30
    • 0026773069 scopus 로고
    • Apoptotic cell death and tissue remodeling during mouse mammary gland involution
    • Strange R, Li F, Saurer S, Burkhardt A, Friis RR. Apoptotic cell death and tissue remodeling during mouse mammary gland involution. Development. 115:1992;49-58.
    • (1992) Development , vol.115 , pp. 49-58
    • Strange, R.1    Li, F.2    Saurer, S.3    Burkhardt, A.4    Friis, R.R.5
  • 31
    • 0030030021 scopus 로고    scopus 로고
    • Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and -dependent pathways
    • Lund LR, Rømer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Danø K, Werb Z. Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development. 122:1996;181-193.
    • (1996) Development , vol.122 , pp. 181-193
    • Lund, L.R.1    Rømer, J.2    Thomasset, N.3    Solberg, H.4    Pyke, C.5    Bissell, M.J.6    Danø, K.7    Werb, Z.8
  • 33
    • 0026061569 scopus 로고
    • Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans
    • Grøndahl-Hansen J, Ralfkiær E, Kirkeby LT, Kristensen P, Lund LR, Danø K. Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans. Amer J Pathol. 138:1991;111-117.
    • (1991) Amer J Pathol , vol.138 , pp. 111-117
    • Grøndahl-Hansen, J.1    Ralfkiær, E.2    Kirkeby, L.T.3    Kristensen, P.4    Lund, L.R.5    Danø, K.6
  • 34
    • 0025853770 scopus 로고
    • Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas
    • Pyke C, Kristensen P, Ralfkiær E, Grøndahl-Hansen J, Eriksen J, Blasi F, Danø K. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Amer J Pathol. 138:1991;1059-1067.
    • (1991) Amer J Pathol , vol.138 , pp. 1059-1067
    • Pyke, C.1    Kristensen, P.2    Ralfkiær, E.3    Grøndahl-Hansen, J.4    Eriksen, J.5    Blasi, F.6    Danø, K.7
  • 35
    • 0028357266 scopus 로고
    • Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer
    • Pyke C, Ralfkiær E, Rønne E, Høyer-Hansen G, Kirkeby L, Danø K. Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer. Histopathol. 24:1994;131-138.
    • (1994) Histopathol , vol.24 , pp. 131-138
    • Pyke, C.1    Ralfkiær, E.2    Rønne, E.3    Høyer-Hansen, G.4    Kirkeby, L.5    Danø, K.6
  • 36
    • 0029894671 scopus 로고    scopus 로고
    • Stromal cell expression of components of matrix-degrading protease systems in human cancer
    • Hewitt R, Danø K. Stromal cell expression of components of matrix-degrading protease systems in human cancer. Enzyme Protein. 49:1996;163-173.
    • (1996) Enzyme Protein , vol.49 , pp. 163-173
    • Hewitt, R.1    Danø, K.2
  • 38
    • 0026338740 scopus 로고
    • Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract
    • Kristensen P, Eriksen J, Blasi F, Danø K. Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract. J Cell Biol. 115:1991;1763-1771.
    • (1991) J Cell Biol , vol.115 , pp. 1763-1771
    • Kristensen, P.1    Eriksen, J.2    Blasi, F.3    Danø, K.4
  • 39
    • 0032031861 scopus 로고    scopus 로고
    • Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
    • of special interest. Two transplanted tumors (Lewis lung carcinoma and B16 melanoma) both show significantly less metastasis to the lungs in matrix metalloproteinase (MMP)-2-deficient mice. As the cancer cells themselves have a fully functional MMP-2 gene, this result points to an important role for host cells as suppliers of MMP-2 activity.
    • Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. of special interest Cancer Res. 58:1998;1048-1051 Two transplanted tumors (Lewis lung carcinoma and B16 melanoma) both show significantly less metastasis to the lungs in matrix metalloproteinase (MMP)-2-deficient mice. As the cancer cells themselves have a fully functional MMP-2 gene, this result points to an important role for host cells as suppliers of MMP-2 activity.
    • (1998) Cancer Res , vol.58 , pp. 1048-1051
    • Itoh, T.1    Tanioka, M.2    Yoshida, H.3    Yoshioka, T.4    Nishimoto, H.5    Itohara, S.6
  • 41
    • 0345251960 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system as a target for prognostic studies in breast cancer
    • in press
    • Stephens RW, Brünner N, Jänicke F, Schmitt M. The urokinase plasminogen activator system as a target for prognostic studies in breast cancer. Breast Cancer Res Treat. 1998;. in press.
    • (1998) Breast Cancer Res Treat
    • Stephens, R.W.1    Brünner, N.2    Jänicke, F.3    Schmitt, M.4
  • 42
    • 0027223048 scopus 로고
    • High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis
    • Grøndahl-Hansen J, Christensen IJ, Rosenquist C, Brünner N, Mouridsen HT, Danø K, Blichert-Toft M. High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Res. 53:1993;2513-2521.
    • (1993) Cancer Res , vol.53 , pp. 2513-2521
    • Grøndahl-Hansen, J.1    Christensen, I.J.2    Rosenquist, C.3    Brünner, N.4    Mouridsen, H.T.5    Danø, K.6    Blichert-Toft, M.7
  • 44
    • 0031948388 scopus 로고    scopus 로고
    • Requirement for both SHC and phosphatidylinositol 3¢ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
    • of special interest. A molecular dissection of a mouse tumor model. Mice were made to express mutant alleles of polyoma middle T-antigen (PymT) with known biochemical defects, and the resulting changes in tumor development were characterized.
    • Webster MA, Hutchinson JN, Rauh MJ, Muthuswamy SK, Anton M, Tortorice CG, Cardiff RD, Graham FL, Hassell JA, Muller WJ. Requirement for both SHC and phosphatidylinositol 3¢ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. of special interest Mol Cell Biol. 18:1998;2344-2359 A molecular dissection of a mouse tumor model. Mice were made to express mutant alleles of polyoma middle T-antigen (PymT) with known biochemical defects, and the resulting changes in tumor development were characterized.
    • (1998) Mol Cell Biol , vol.18 , pp. 2344-2359
    • Webster, M.A.1    Hutchinson, J.N.2    Rauh, M.J.3    Muthuswamy, S.K.4    Anton, M.5    Tortorice, C.G.6    Cardiff, R.D.7    Graham, F.L.8    Hassell, J.A.9    Muller, W.J.10


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