-
1
-
-
11144245547
-
Activity-based protein profiling: Applications to biomarker discovery, in vivo imaging and drug discovery
-
Berger, A.B., Vitorino, P.M. & Bogyo, M. Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery. Am. J. Pharmacogenomics 4, 371-381 (2004).
-
(2004)
Am. J. Pharmacogenomics
, vol.4
, pp. 371-381
-
-
Berger, A.B.1
Vitorino, P.M.2
Bogyo, M.3
-
2
-
-
33748595526
-
Mechanism-based profiling of enzyme families
-
Evans, M.J. & Cravatt, B.F. Mechanism-based profiling of enzyme families. Chem. Rev. 106, 3279-3301 (2006).
-
(2006)
Chem. Rev
, vol.106
, pp. 3279-3301
-
-
Evans, M.J.1
Cravatt, B.F.2
-
3
-
-
33846807650
-
Tagging and detection strategies for activity-based proteomics
-
Sadaghiani, A.M., Verhelst, S.H. & Bogyo, M. Tagging and detection strategies for activity-based proteomics. Curr. Opin. Chem. Biol. 11, 20-28 (2006).
-
(2006)
Curr. Opin. Chem. Biol
, vol.11
, pp. 20-28
-
-
Sadaghiani, A.M.1
Verhelst, S.H.2
Bogyo, M.3
-
4
-
-
84984752764
-
Assignment of protein function in the postgenomic era
-
Saghatelian, A. & Cravatt, B.F. Assignment of protein function in the postgenomic era. Nat. Chem. Biol. 1, 130-142 (2005).
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 130-142
-
-
Saghatelian, A.1
Cravatt, B.F.2
-
5
-
-
33745104981
-
Activity-based proteomics: Enzymatic activity profiling in complex proteomes
-
Schmidinger, H., Hermetter, A. & Birner-Gruenberger, R. Activity-based proteomics: enzymatic activity profiling in complex proteomes. Amino Acids 30, 333-350 (2006).
-
(2006)
Amino Acids
, vol.30
, pp. 333-350
-
-
Schmidinger, H.1
Hermetter, A.2
Birner-Gruenberger, R.3
-
6
-
-
0036051482
-
Chemical approaches for functionally probing the proteome
-
Greenbaum, D. et al. Chemical approaches for functionally probing the proteome. Mol. Cell. Proteomics 1, 60-68 (2002).
-
(2002)
Mol. Cell. Proteomics
, vol.1
, pp. 60-68
-
-
Greenbaum, D.1
-
7
-
-
0035469599
-
Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes
-
Patricelli, M.P., Giang, D.K., Stamp, L.M. & Burbaum, J.J. Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes. Proteomics 1, 1067-1071 (2001).
-
(2001)
Proteomics
, vol.1
, pp. 1067-1071
-
-
Patricelli, M.P.1
Giang, D.K.2
Stamp, L.M.3
Burbaum, J.J.4
-
8
-
-
3042831921
-
Activity-based probes for the proteomic profiling of metalloproteases
-
Saghatelian, A., Jessani, N., Joseph, A., Humphrey, M. & Cravatt, B.F. Activity-based probes for the proteomic profiling of metalloproteases. Proc. Natl. Acad. Sci. USA 101, 10000-10005 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10000-10005
-
-
Saghatelian, A.1
Jessani, N.2
Joseph, A.3
Humphrey, M.4
Cravatt, B.F.5
-
9
-
-
33646462162
-
Proteomic profiling of metalloprotease activities with cocktails of active-site probes
-
Sieber, S.A., Niessen, S., Hoover, H.S. & Cravatt, B.F. Proteomic profiling of metalloprotease activities with cocktails of active-site probes. Nat. Chem. Biol. 2, 274-281 (2006).
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 274-281
-
-
Sieber, S.A.1
Niessen, S.2
Hoover, H.S.3
Cravatt, B.F.4
-
10
-
-
0036882393
-
Human and parasitic papain-like cysteine proteases: Their role in physiology and pathology and recent developments in inhibitor design
-
Lecaille, F., Kaleta, J. & Bromme, D. Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design. Chem. Rev. 102, 4459-4488 (2002).
-
(2002)
Chem. Rev
, vol.102
, pp. 4459-4488
-
-
Lecaille, F.1
Kaleta, J.2
Bromme, D.3
-
11
-
-
33748524564
-
Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease
-
Mueller-Steiner, S. et al. Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Neuron 51, 703-714 (2006).
-
(2006)
Neuron
, vol.51
, pp. 703-714
-
-
Mueller-Steiner, S.1
-
12
-
-
10044296973
-
Cysteine cathepsins in human cancer
-
Jedeszko, C. & Sloane, B.F. Cysteine cathepsins in human cancer. Biol. Chem. 385, 1017-1027 (2004).
-
(2004)
Biol. Chem
, vol.385
, pp. 1017-1027
-
-
Jedeszko, C.1
Sloane, B.F.2
-
13
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
Mohamed, M.M. & Sloane, B.F. Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 6, 764-775 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
14
-
-
0031887693
-
Prognostic significance of cathepsins B and L in primary human breast cancer
-
Foekens, J.A. et al. Prognostic significance of cathepsins B and L in primary human breast cancer. J. Clin. Oncol. 16, 1013-1021 (1998).
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 1013-1021
-
-
Foekens, J.A.1
-
15
-
-
0034802806
-
Prognostic impact of proteolytic factors (urokinase-type plasminogen activator, plasminogen activator inhibitor 1, and cathepsins B, D, and L) in primary breast cancer reflects effects of adjuvant systemic therapy
-
Harbeck, N. et al. Prognostic impact of proteolytic factors (urokinase-type plasminogen activator, plasminogen activator inhibitor 1, and cathepsins B, D, and L) in primary breast cancer reflects effects of adjuvant systemic therapy. Clin. Cancer Res. 7, 2757-2764 (2001).
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 2757-2764
-
-
Harbeck, N.1
-
16
-
-
14744277142
-
Prognostic and predictive value of cathepsins D and L in operable breast cancer patients
-
Jagodic, M., Vrhovec, I., Borstnar, S. & Cufer, T. Prognostic and predictive value of cathepsins D and L in operable breast cancer patients. Neoplasma 52, 1-9 (2005).
-
(2005)
Neoplasma
, vol.52
, pp. 1-9
-
-
Jagodic, M.1
Vrhovec, I.2
Borstnar, S.3
Cufer, T.4
-
17
-
-
0343340434
-
Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: Comparison with cathepsin D, cathepsin L, and other clinical indicators
-
Lah, T.T. et al. Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L, and other clinical indicators. Clin. Cancer Res. 6, 578-584 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 578-584
-
-
Lah, T.T.1
-
18
-
-
33644784910
-
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
-
Gocheva, V. et al. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 20, 543-556 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 543-556
-
-
Gocheva, V.1
-
19
-
-
2342603891
-
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
-
Joyce, J.A. et al. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 5, 443-453 (2004).
-
(2004)
Cancer Cell
, vol.5
, pp. 443-453
-
-
Joyce, J.A.1
-
20
-
-
20044373820
-
Cathepsin L is required for endothelial progenitor cell-induced neovascularization
-
Urbich, C. et al. Cathepsin L is required for endothelial progenitor cell-induced neovascularization. Nat. Med. 11, 206-213 (2005).
-
(2005)
Nat. Med
, vol.11
, pp. 206-213
-
-
Urbich, C.1
-
21
-
-
33744917827
-
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
-
Vasiljeva, O. et al. Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res. 66, 5242-5250 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 5242-5250
-
-
Vasiljeva, O.1
-
22
-
-
1642516135
-
Current advances in molecular imaging: Noninvasive in vivo bioluminescent and fluorescent optical imaging in cancer research
-
Choy, G., Choyke, P. & Libutti, S.K. Current advances in molecular imaging: noninvasive in vivo bioluminescent and fluorescent optical imaging in cancer research. Mol. Imaging 2, 303-312 (2003).
-
(2003)
Mol. Imaging
, vol.2
, pp. 303-312
-
-
Choy, G.1
Choyke, P.2
Libutti, S.K.3
-
23
-
-
20444372316
-
Optical imaging in drug discovery and diagnostic applications
-
Licha, K. & Olbrich, C. Optical imaging in drug discovery and diagnostic applications. Adv. Drug Deliv. Rev. 57, 1087-1108 (2005).
-
(2005)
Adv. Drug Deliv. Rev
, vol.57
, pp. 1087-1108
-
-
Licha, K.1
Olbrich, C.2
-
24
-
-
16344363226
-
Molecular optical imaging: Applications leading to the development of present day therapeutics
-
Shah, K. & Weissleder, R. Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx 2, 215-225 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 215-225
-
-
Shah, K.1
Weissleder, R.2
-
25
-
-
0347915584
-
Enzyme activity-it's all about image
-
Baruch, A., Jeffery, D.A. & Bogyo, M. Enzyme activity-it's all about image. Trends Cell Biol. 14, 29-35 (2004).
-
(2004)
Trends Cell Biol
, vol.14
, pp. 29-35
-
-
Baruch, A.1
Jeffery, D.A.2
Bogyo, M.3
-
26
-
-
19544391442
-
Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes
-
Bremer, C. et al. Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest. Radiol. 40, 321-327 (2005).
-
(2005)
Invest. Radiol
, vol.40
, pp. 321-327
-
-
Bremer, C.1
-
27
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
Jiang, T. et al. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc. Natl. Acad. Sci. USA 101, 17867-17872 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17867-17872
-
-
Jiang, T.1
-
28
-
-
0034283034
-
In vivo imaging of proteolytic enzyme activity using a novel molecular reporter
-
Tung, C.H., Mahmood, U., Bredow, S. & Weissleder, R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res. 60, 4953-4958 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 4953-4958
-
-
Tung, C.H.1
Mahmood, U.2
Bredow, S.3
Weissleder, R.4
-
29
-
-
0032951071
-
-
Weissleder, R., Tung, C.H., Mahmood, U. & Bogdanov, A., Jr In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat. Biotechnol. 17, 375-378 (1999).
-
Weissleder, R., Tung, C.H., Mahmood, U. & Bogdanov, A., Jr In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat. Biotechnol. 17, 375-378 (1999).
-
-
-
-
30
-
-
33644825565
-
Dynamic imaging of protease activity with fluorescently quenched activity-based probes
-
Blum, G. et al. Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nat. Chem. Biol. 1, 203-209 (2005).
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 203-209
-
-
Blum, G.1
-
31
-
-
0030000541
-
Cathepsins D, B, and L in malignant human lung tissue
-
Ledakis, P. et al. Cathepsins D, B, and L in malignant human lung tissue. Clin. Cancer Res. 2, 561-568 (1996).
-
(1996)
Clin. Cancer Res
, vol.2
, pp. 561-568
-
-
Ledakis, P.1
-
32
-
-
0033656021
-
Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: Implications for cancer gene therapy without tumor targeting
-
D'Orazi, G. et al. Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting. J. Gene Med. 2, 11-21 (2000).
-
(2000)
J. Gene Med
, vol.2
, pp. 11-21
-
-
D'Orazi, G.1
-
33
-
-
25444510617
-
Breast cancer cell lines grown in vivo: What goes in isn't always the same as what comes out
-
Jessani, N., Niessen, S., Mueller, B.M. & Cravatt, B.F. Breast cancer cell lines grown in vivo: what goes in isn't always the same as what comes out. Cell Cycle 4, 253-255 (2005).
-
(2005)
Cell Cycle
, vol.4
, pp. 253-255
-
-
Jessani, N.1
Niessen, S.2
Mueller, B.M.3
Cravatt, B.F.4
-
34
-
-
0034054576
-
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
-
Bogyo, M., Verhelst, S., Bellingard-Dubouchaud, V., Toba, S. & Greenbaum, D. Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs. Chem. Biol. 7, 27-38 (2000).
-
(2000)
Chem. Biol
, vol.7
, pp. 27-38
-
-
Bogyo, M.1
Verhelst, S.2
Bellingard-Dubouchaud, V.3
Toba, S.4
Greenbaum, D.5
-
35
-
-
0029099619
-
Vinyl sulfones as mechanism-based cysteine protease inhibitors
-
Palmer, J.T., Rasnick, D., Klaus, J.L. & Bromme, D. Vinyl sulfones as mechanism-based cysteine protease inhibitors. J. Med. Chem. 38, 3193-3196 (1995).
-
(1995)
J. Med. Chem
, vol.38
, pp. 3193-3196
-
-
Palmer, J.T.1
Rasnick, D.2
Klaus, J.L.3
Bromme, D.4
-
36
-
-
0024367097
-
Glycosylation of procathepsin L does not account for species molecular-mass differences and is not required for proteolytic activity
-
Smith, S.M., Kane, S.E., Gal, S., Mason, R.W. & Gottesman, M.M. Glycosylation of procathepsin L does not account for species molecular-mass differences and is not required for proteolytic activity. Biochem. J. 262, 931-938 (1989).
-
(1989)
Biochem. J
, vol.262
, pp. 931-938
-
-
Smith, S.M.1
Kane, S.E.2
Gal, S.3
Mason, R.W.4
Gottesman, M.M.5
-
37
-
-
0032170483
-
Substrate specificity of prostate-specific antigen (PSA)
-
Coombs, G.S. et al. Substrate specificity of prostate-specific antigen (PSA). Chem. Biol. 5, 475-488 (1998).
-
(1998)
Chem. Biol
, vol.5
, pp. 475-488
-
-
Coombs, G.S.1
-
38
-
-
0035947634
-
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin
-
Liu, S., Bugge, T.H. & Leppla, S.H. Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin. J. Biol. Chem. 276, 17976-17984 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 17976-17984
-
-
Liu, S.1
Bugge, T.H.2
Leppla, S.H.3
-
39
-
-
29444460784
-
Activity-based probes that target diverse cysteine protease families
-
Kato, D. et al. Activity-based probes that target diverse cysteine protease families. Nat. Chem. Biol. 1, 33-38 (2005).
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 33-38
-
-
Kato, D.1
|