Epigenetic targets for novel therapies of lung diseases

Pharmacology and Therapeutics

Volumn 147, Issue , 2015, Pages 91-110

  Comer, Brian S ^a   Ba, Mariam ^b   Singer, Cherie A ^b   Gerthoffer, William T ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; COPD; DNA methylation; Fibrosis; Histone code; Noncoding; RNA

Indexed keywords

2 METHOXY N (1,2,3,4 TETRAHYDRO 3 METHYL 2 OXO 6 QUINAZOLINYL)BENZENESULFONAMIDE; 3 DEAZANEPLANOCIN; 4 (4 CHLOROPHENYL) 2,3,9 TRIMETHYL 6H THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE 6 ACETIC ACID TERT BUTYL ESTER; 5 AZA 2' DEOXYCYTIDINE; ANTISENSE OLIGONUCLEOTIDE; AZACITIDINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BLEOMYCIN; BRONCHODILATING AGENT; C 646; CORTICOSTEROID; CURCUMIN; DNA METHYLTRANSFERASE INHIBITOR; ENZYME INHIBITOR; EPZ 005687; GSK 126; HISTONE DEACETYLASE INHIBITOR; HISTONE METHYLTRANSFERASE INHIBITOR; LONG ACTING DRUG; MICRORNA; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; PANOBINOSTAT; QUERCETIN; SMALL INTERFERING RNA; THEOPHYLLINE; TRICHOSTATIN A; UNC 1999; UNCLASSIFIED DRUG; UNINDEXED DRUG; UNTRANSLATED RNA; VORINOSTAT;

AIRWAY REMODELING; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CUTANEOUS T CELL LYMPHOMA; DNA METHYLATION; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG MECHANISM; DRUG TARGETING; EPIGENETICS; FIBROSING ALVEOLITIS; GENE EXPRESSION REGULATION; GENE FUNCTION; HISTONE MODIFICATION; HUMAN; LUNG DISEASE; MULTIPLE MYELOMA; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REVIEW; SEVERE PERSISTENT ASTHMA; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; TREATMENT RESPONSE; VASCULAR REMODELING; ANIMAL; DRUG EFFECTS; GENE TARGETING; GENETIC EPIGENESIS; GENETICS; LUNG DISEASES; PROCEDURES; TRENDS;

ANIMALS; BRONCHODILATOR AGENTS; DNA METHYLATION; DRUG DELIVERY SYSTEMS; EPIGENESIS, GENETIC; GENE TARGETING; HUMANS; LUNG DISEASES;

EID: 84922670521     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.11.006     Document Type: Review

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