Transcriptome analysis shows activation of circulating CD8 + T cells in patients with severe asthma

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 1, 2012, Pages 95-103

  Tsitsiou, Eleni ^a   Williams, Andrew E ^b   Moschos, Sterghios A ^c   Patel, Ketan ^c   Rossios, Christos ^b   Jiang, Xiaoying ^a   Adams, Oona Delpuech ^c   MacEdo, Patricia ^b   Booton, Richard ^a   Gibeon, David ^b   Chung, Kian Fan ^b   Lindsay, Mark A ^a,b,d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d University of Bath   (United Kingdom)

Author keywords

CD8 + T cells; long noncoding RNA; microRNA; Severe asthma; transcriptome

Indexed keywords

COMPLEMENTARY RNA; INTERGENIC LONG UNTRANSLATED RNA; INTRONIC LONG UNTRANSLATED RNA; MESSENGER RNA; MICRORNA; TRANSCRIPTOME; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ADULT; ARTICLE; ASTHMA; BIOINFORMATICS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; INTRON; MALE; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOGENE; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTOMICS;

ADULT; ASTHMA; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MICRORNAS; MIDDLE AGED; RNA, MESSENGER; RNA, UNTRANSLATED; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84455191835     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.08.011     Document Type: Article

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