Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke

American Journal of Respiratory Cell and Molecular Biology

Volumn 40, Issue 4, 2009, Pages 464-473

  Adenuga, David ^a   Yao, Hongwei ^a   March, Thomas H ^b   Seagrave, JeanClare ^b   Rahman, Irfan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Cigarette smoke; COPD; HDAC2; Inflammation; Lung

Indexed keywords

CASEIN KINASE II; CIGARETTE SMOKE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEASOME; PROTEIN SERINE THREONINE KINASE INHIBITOR; UBIQUITIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE-2; REPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; MACROPHAGE; MALE; MOUSE; NONHUMAN; RESPIRATORY EPITHELIUM; UBIQUITINATION; ANIMAL; BRONCHUS; CELL LINE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; SMOKE; SMOKING; TIME; TOBACCO;

MUS;

ANIMALS; BRONCHI; CASEIN KINASE II; CELL LINE; EPITHELIAL CELLS; FEMALE; HISTONE DEACETYLASES; HUMANS; MALE; MICE; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPRESSOR PROTEINS; SMOKE; SMOKING; TIME FACTORS; TOBACCO; UBIQUITIN; UBIQUITINATION;

EID: 63349102653     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0255OC     Document Type: Article

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