MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 5, 2014, Pages

  Malmhäll, Carina ^a   Alawieh, Sahar ^a   Lu, You ^a   Sjöstrand, Margareta ^a   Bossios, Apostolos ^a   Eldh, Maria ^a   Rådinger, Madeleine ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

allergy; asthma; eosinophils; inflammation; MicroRNA; miR 155

Indexed keywords

ALLERGEN; EOTAXIN 2; MICRORNA 155; OVALBUMIN; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR RUNX2; CYTOKINE;

ADOPTIVE TRANSFER; AIRWAY; ALLERGEN INDUCED EOSINOPHILIC INFLAMMATION; ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IN VIVO STUDY; MALE; MOUSE; MUCUS; NONHUMAN; PRIORITY JOURNAL; TH2 CELL; WILD TYPE; ALLERGIC ASTHMA; CD4 LYMPHOCYTE COUNT; CYTOKINE RELEASE; EOSINOPHIL; EOSINOPHILIA; FLOW CYTOMETRY; IMMUNE RESPONSE; INFLAMMATION; MOUSE MODEL; MUCUS SECRETION;

ALLERGY; ASTHMA; EOSINOPHILS; INFLAMMATION; MICRORNA; MIR-155; T(H) CELLS;

ADOPTIVE TRANSFER; ALLERGENS; ANIMALS; CHEMOKINE CCL24; EOSINOPHILS; INFLAMMATION; LUNG; MICE; MICE, KNOCKOUT; MICRORNAS; PNEUMONIA; PROTO-ONCOGENE PROTEINS; RESPIRATORY HYPERSENSITIVITY; TH2 CELLS; TRANS-ACTIVATORS;

EID: 84899656541     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.11.008     Document Type: Article

References (45)

1. H. Bowen, A. Kelly, T. Lee, and P. Lavender Control of cytokine gene transcription in Th1 and Th2 cells Clin Exp Allergy 38 2008 1422 1431
2. S.T. Holgate Innate and adaptive immune responses in asthma Nat Med 18 2012 673 683
3. J. Das, C.H. Chen, L. Yang, L. Cohn, P. Ray, and A. Ray A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation Nat Immunol 2 2001 45 50
4. R.F. Lemanske Jr., and W.W. Busse Asthma: clinical expression and molecular mechanisms J Allergy Clin Immunol 125 Suppl 2 2010 S95 S102
5. D.A. Kuperman, X. Huang, L.L. Koth, G.H. Chang, G.M. Dolganov, and Z. Zhu et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma Nat Med 8 2002 885 889
6. J. Mattes, A. Collison, and P.S. Foster Emerging role of microRNAs in disease pathogenesis and strategies for therapeutic modulation Curr Opin Mol Ther 10 2008 150 157
7. C. Xiao, and K. Rajewsky MicroRNA control in the immune system: basic principles Cell 136 2009 26 36
8. T.X. Lu, and M.E. Rothenberg Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases J Allergy Clin Immunol 132 2013 3 13
9. A. Rebane, and C.A. Akdis MicroRNAs: essential players in the regulation of inflammation J Allergy Clin Immunol 132 2013 15 26
10. T.X. Lu, A. Munitz, and M.E. Rothenberg MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression J Immunol 182 2009 4994 5002
11. J. Mattes, A. Collison, M. Plank, S. Phipps, and P.S. Foster Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease Proc Natl Acad Sci U S A 106 2009 18704 18709
12. A. Collison, J. Mattes, M. Plank, and P.S. Foster Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment J Allergy Clin Immunol 128 2011 160 167.e4
13. I. Faraoni, F.R. Antonetti, J. Cardone, and E. Bonmassar miR-155 gene: a typical multifunctional microRNA Biochim Biophys Acta 1792 2009 497 505
14. A. Rodriguez, E. Vigorito, S. Clare, M.V. Warren, P. Couttet, and D.R. Soond et al. Requirement of bic/microRNA-155 for normal immune function Science 316 2007 608 611
15. S. Kohlhaas, O.A. Garden, C. Scudamore, M. Turner, K. Okkenhaug, and E. Vigorito Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells J Immunol 182 2009 2578 2582
16. L.F. Lu, T.H. Thai, D.P. Calado, A. Chaudhry, M. Kubo, and K. Tanaka et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein Immunity 30 2009 80 91
17. M. Oertli, D.B. Engler, E. Kohler, M. Koch, T.F. Meyer, and A. Muller MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic gastritis and colitis J Immunol 187 2011 3578 3586
18. S. Bluml, M. Bonelli, B. Niederreiter, A. Puchner, G. Mayr, and S. Hayer et al. Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice Arthritis Rheum 63 2011 1281 1288
19. M.N. Blumenthal, C.D. Langefeld, K.C. Barnes, C. Ober, D.A. Meyers, and R.A. King et al. A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity J Allergy Clin Immunol 117 2006 79 85
20. H. Suojalehto, E. Toskala, M. Kilpelainen, M.L. Majuri, C. Mitts, and I. Lindstrom et al. MicroRNA profiles in nasal mucosa of patients with allergic and nonallergic rhinitis and asthma Int Forum Allergy Rhinol 3 2013 612 620
21. E. Sonkoly, P. Janson, M.L. Majuri, T. Savinko, N. Fyhrquist, and L. Eidsmo et al. MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4 J Allergy Clin Immunol 126 2010 581 589 e1-20
22. M. Rådinger, A.K. Johansson, B. Sitkauskiene, M. Sjöstrand, and J. Lötvall Eotaxin-2 regulates newly produced and CD34 airway eosinophils after allergen exposure J Allergy Clin Immunol 113 2004 1109 1116
23. S.M. Pope, N. Zimmermann, K.F. Stringer, M.L. Karow, and M.E. Rothenberg The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia J Immunol 175 2005 5341 5350
24. D. Haasch, Y.W. Chen, R.M. Reilly, X.G. Chiou, S. Koterski, and M.L. Smith et al. T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC Cell Immunol 217 2002 78 86
25. Y. Lu, C. Malmhäll, M. Sjöstrand, M. Rådinger, S.E. O'Neil, and J. Lötvall et al. Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORgammat cells in allergic inflammation, local lung distribution and chemokine gene expression PLoS One 6 2011 e19889
26. E. Vigorito, K.L. Perks, C. Abreu-Goodger, S. Bunting, Z. Xiang, and S. Kohlhaas et al. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells Immunity 27 2007 847 859
27. H.C. Chang, S. Zhang, V.T. Thieu, R.B. Slee, H.A. Bruns, and R.N. Laribee et al. PU.1 expression delineates heterogeneity in primary Th2 cells Immunity 22 2005 693 703
28. C.M. Lloyd, and E.M. Hessel Functions of T cells in asthma: more than just T(H)2 cells Nat Rev Immunol 10 2010 838 848
29. K.L. Asquith, H.S. Ramshaw, P.M. Hansbro, K.W. Beagley, A.F. Lopez, and P.S. Foster The IL-3/IL-5/GM-CSF common receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammation J Immunol 180 2008 1199 1206
30. R.T. Palframan, P.D. Collins, T.J. Williams, and S.M. Rankin Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow Blood 91 1998 2240 2248
31. N. Zimmermann, G.K. Hershey, P.S. Foster, and M.E. Rothenberg Chemokines in asthma: cooperative interaction between chemokines and IL-13 J Allergy Clin Immunol 111 2003 227 242
32. M. Yang, S.P. Hogan, S. Mahalingam, S.M. Pope, N. Zimmermann, and P. Fulkerson et al. Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity J Allergy Clin Immunol 112 2003 935 943
33. H.F. Rosenberg, S. Phipps, and P.S. Foster Eosinophil trafficking in allergy and asthma J Allergy Clin Immunol 119 2007 1303 1310
34. S.M. Pope, P.C. Fulkerson, C. Blanchard, H.S. Akei, N.M. Nikolaidis, and N. Zimmermann et al. Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation J Biol Chem 280 2005 13952 13961
35. M. Rådinger, A. Bossios, A.S. Alm, P. Jeurink, Y. Lu, and C. Malmhäll et al. Regulation of allergen-induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells Allergy 62 2007 1410 1418
36. M. Yang, R.K. Kumar, P.M. Hansbro, and P.S. Foster Emerging roles of pulmonary macrophages in driving the development of severe asthma J Leukoc Biol 91 2012 557 569
37. Z. Zhu, R.J. Homer, Z. Wang, Q. Chen, G.P. Geba, and J. Wang et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production J Clin Invest 103 1999 779 788
38. R.K. Kumar, C. Herbert, M. Yang, A.M. Koskinen, A.N. McKenzie, and P.S. Foster Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma Clin Exp Allergy 32 2002 1104 1111
39. G. Jia, R.W. Erickson, D.F. Choy, S. Mosesova, L.C. Wu, and O.D. Solberg et al. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients J Allergy Clin Immunol 130 2012 647 654.e10
40. M. Masuoka, H. Shiraishi, S. Ohta, S. Suzuki, K. Arima, and S. Aoki et al. Periostin promotes chronic allergic inflammation in response to Th2 cytokines J Clin Invest 122 2012 2590 2600
41. C. Blanchard, M.K. Mingler, M. McBride, P.E. Putnam, M.H. Collins, and G. Chang et al. Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses Mucosal Immunol 1 2008 289 296
42. R. Yao, Y.L. Ma, W. Liang, H.H. Li, Z.J. Ma, and X. Yu et al. MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1 PLoS One 7 2012 e46082
43. R.M. O'Connell, D. Kahn, W.S. Gibson, J.L. Round, R.L. Scholz, and A.A. Chaudhuri et al. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development Immunity 33 2010 607 619
44. V. Ambros The functions of animal microRNAs Nature 431 2004 350 355
45. C. Malmhäll, A. Bossios, T. Pullerits, and J. Lötvall Effects of pollen and nasal glucocorticoid on FOXP3+, GATA-3+ and T-bet+ cells in allergic rhinitis Allergy 62 2007 1007 1013