-
1
-
-
78650744437
-
Tailor-made RNAi knockdown against triplet repeat disease-causing alleles
-
Takahashi, M, Watanabe, S, Murata, M, Furuya, H, Kanazawa, I, Wada, K et al. (2010). Tailor-made RNAi knockdown against triplet repeat disease-causing alleles. Proc Natl Acad Sci USA 107: 21731-21736.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21731-21736
-
-
Takahashi, M.1
Watanabe, S.2
Murata, M.3
Furuya, H.4
Kanazawa, I.5
Wada, K.6
-
2
-
-
79959330427
-
Effcient allele-specifc targeting of LRRK2 R1441 mutations mediated by RNAi
-
de Yñigo-Mojado, L, Martín-Ruíz, I and Sutherland, JD (2011). Effcient allele-specifc targeting of LRRK2 R1441 mutations mediated by RNAi. PLoS ONE 6: e21352.
-
(2011)
PLoS ONE
, vol.6
-
-
De Yñigo-Mojado, L.1
Martín-Ruíz, I.2
Sutherland, J.D.3
-
3
-
-
84856913587
-
Pyruvate kinase M2-specifc siRNA induces apoptosis and tumor regression
-
Goldberg, MS and Sharp, PA (2012). Pyruvate kinase M2-specifc siRNA induces apoptosis and tumor regression. J Exp Med 209: 217-224.
-
(2012)
J Exp Med
, vol.209
, pp. 217-224
-
-
Goldberg, M.S.1
Sharp, P.A.2
-
4
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
DOI 10.1016/S0092-8674(03)00801-8
-
Khvorova, A, Reynolds, A and Jayasena, SD (2003). Functional siRNAs and miRNAs exhibit strand bias. Cell 115: 209-216. (Pubitemid 37329584)
-
(2003)
Cell
, vol.115
, Issue.2
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
5
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
DOI 10.1016/S0092-8674(03)00759-1
-
Schwarz, DS, Hutvágner, G, Du, T, Xu, Z, Aronin, N and Zamore, PD (2003). Asymmetry in the assembly of the RNAi enzyme complex. Cell 115: 199-208. (Pubitemid 37329583)
-
(2003)
Cell
, vol.115
, Issue.2
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
6
-
-
57449107290
-
Asymmetric RNA duplexes mediate RNA interference in mammalian cells
-
Sun, X, Rogoff, HA and Li, CJ (2008). Asymmetric RNA duplexes mediate RNA interference in mammalian cells. Nat Biotechnol 26: 1379-1382.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1379-1382
-
-
Sun, X.1
Rogoff, H.A.2
Li, C.J.3
-
7
-
-
63949084982
-
Asymmetric shorter-duplex siRNA structures trigger effcient gene silencing with reduced nonspecifc effects
-
Chang, CI, Yoo, JW, Hong, SW, Lee, SE, Kang, HS, Sun, X et al. (2009). Asymmetric shorter-duplex siRNA structures trigger effcient gene silencing with reduced nonspecifc effects. Mol Ther 17: 725-732.
-
(2009)
Mol Ther
, vol.17
, pp. 725-732
-
-
Chang, C.I.1
Yoo, J.W.2
Hong, S.W.3
Lee, S.E.4
Kang, H.S.5
Sun, X.6
-
8
-
-
83055164366
-
Improved siRNA/shRNA functionality by mismatched duplex
-
Wu, H, Ma, H, Ye, C, Ramirez, D, Chen, S, Montoya, J et al. (2011). Improved siRNA/shRNA functionality by mismatched duplex. PLoS ONE 6: e28580.
-
(2011)
PLoS ONE
, vol.6
-
-
Wu, H.1
Ma, H.2
Ye, C.3
Ramirez, D.4
Chen, S.5
Montoya, J.6
-
9
-
-
38649099969
-
Strand-specific 5′-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
-
DOI 10.1261/rna.789808
-
Chen, PY, Weinmann, L, Gaidatzis, D, Pei, Y, Zavolan, M, Tuschl, T et al. (2008). Strand-specifc 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specifcity. RNA 14: 263-274. (Pubitemid 351171587)
-
(2008)
RNA
, vol.14
, Issue.2
, pp. 263-274
-
-
Po, Y.C.1
Weinmann, L.2
Gaidatzis, D.3
Pei, Y.4
Zavolan, M.5
Tuschl, T.6
Meister, G.7
-
10
-
-
67651112027
-
UNA (unlocked nucleic acid): A fexible RNA mimic that allows engineering of nucleic acid duplex stability
-
Langkjaer, N, Pasternak, A and Wengel, J (2009). UNA (unlocked nucleic acid): a fexible RNA mimic that allows engineering of nucleic acid duplex stability. Bioorg Med Chem 17: 5420-5425.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 5420-5425
-
-
Langkjaer, N.1
Pasternak, A.2
Wengel, J.3
-
11
-
-
78049354836
-
Thermodynamics of RNA duplexes modifed with unlocked nucleic acid nucleotides
-
Pasternak, A and Wengel, J (2010). Thermodynamics of RNA duplexes modifed with unlocked nucleic acid nucleotides. Nucleic Acids Res 38: 6697-6706.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6697-6706
-
-
Pasternak, A.1
Wengel, J.2
-
12
-
-
77449136824
-
Analysis of acyclic nucleoside modifcations in siRNAs fnds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo
-
Kenski, DM, Cooper, AJ, Li, JJ, Willingham, AT, Haringsma, HJ, Young, TA et al. (2010). Analysis of acyclic nucleoside modifcations in siRNAs fnds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Nucleic Acids Res 38: 660-671.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 660-671
-
-
Kenski, D.M.1
Cooper, A.J.2
Li, J.J.3
Willingham, A.T.4
Haringsma, H.J.5
Young, T.A.6
-
13
-
-
77957241115
-
A screen of chemical modifcations identifes position-specifc modifcation by UNA to most potently reduce siRNA off-target effects
-
Bramsen, JB, Pakula, MM, Hansen, TB, Bus, C, Langkjær, N, Odadzic, D et al. (2010). A screen of chemical modifcations identifes position-specifc modifcation by UNA to most potently reduce siRNA off-target effects. Nucleic Acids Res 38: 5761-5773.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5761-5773
-
-
Bramsen, J.B.1
Pakula, M.M.2
Hansen, T.B.3
Bus, C.4
Langkjær, N.5
Odadzic, D.6
-
14
-
-
79953144826
-
Improved specifcity of gene silencing by siRNAs containing unlocked nucleobase analogs
-
Vaish, N, Chen, F, Seth, S, Fosnaugh, K, Liu, Y, Adami, R et al. (2011). Improved specifcity of gene silencing by siRNAs containing unlocked nucleobase analogs. Nucleic Acids Res 39: 1823-1832.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1823-1832
-
-
Vaish, N.1
Chen, F.2
Seth, S.3
Fosnaugh, K.4
Liu, Y.5
Adami, R.6
-
15
-
-
77952329345
-
Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo
-
Laursen, MB, Pakula, MM, Gao, S, Fluiter, K, Mook, OR, Baas, F et al. (2010). Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo. Mol Biosyst 6: 862-870.
-
(2010)
Mol Biosyst
, vol.6
, pp. 862-870
-
-
Laursen, M.B.1
Pakula, M.M.2
Gao, S.3
Fluiter, K.4
Mook, O.R.5
Baas, F.6
-
16
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
DOI 10.1038/nbt1051
-
Kim, DH, Behlke, MA, Rose, SD, Chang, MS, Choi, S and Rossi, JJ (2005). Synthetic dsRNA Dicer substrates enhance RNAi potency and effcacy. Nat Biotechnol 23: 222-226. (Pubitemid 40255333)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.2
, pp. 222-226
-
-
Kim, D.-H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.-S.4
Choi, S.5
Rossi, J.J.6
-
17
-
-
22844448088
-
Functional polarity is introduced by Dicer processing of short substrate RNAs
-
DOI 10.1093/nar/gki732
-
Rose, SD, Kim, DH, Amarzguioui, M, Heidel, JD, Collingwood, MA, Davis, ME et al. (2005). Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res 33: 4140-4156. (Pubitemid 41487274)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.13
, pp. 4140-4156
-
-
Rose, S.D.1
Kim, D.-H.2
Amarzguioui, M.3
Heidel, J.D.4
Collingwood, M.A.5
Davis, M.E.6
Rossi, J.J.7
Behlke, M.A.8
-
18
-
-
0034327407
-
Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription
-
Beerens, N, Groot, F and Berkhout, B (2000). Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription. Nucleic Acids Res 28: 4130-4137.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4130-4137
-
-
Beerens, N.1
Groot, F.2
Berkhout, B.3
-
19
-
-
79952358406
-
A role for human Dicer in pre-RISC loading of siRNAs
-
Sakurai, K, Amarzguioui, M, Kim, DH, Alluin, J, Heale, B, Song, MS et al. (2011). A role for human Dicer in pre-RISC loading of siRNAs. Nucleic Acids Res 39: 1510-1525.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1510-1525
-
-
Sakurai, K.1
Amarzguioui, M.2
Kim, D.H.3
Alluin, J.4
Heale, B.5
Song, M.S.6
-
20
-
-
26444437334
-
SiRNA target site secondary structure predictions using local stable substructures
-
Heale, BS, Soifer, HS, Bowers, C and Rossi, JJ (2005). siRNA target site secondary structure predictions using local stable substructures. Nucleic Acids Res 33: e30.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Heale, B.S.1
Soifer, H.S.2
Bowers, C.3
Rossi, J.J.4
-
21
-
-
79955572694
-
RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancer
-
Seth, S, Matsui, Y, Fosnaugh, K, Liu, Y, Vaish, N, Adami, R et al. (2011). RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancer. Mol Ther 19: 928-935.
-
(2011)
Mol Ther
, vol.19
, pp. 928-935
-
-
Seth, S.1
Matsui, Y.2
Fosnaugh, K.3
Liu, Y.4
Vaish, N.5
Adami, R.6
-
22
-
-
0028009774
-
Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses
-
Chen, BK, Saksela, K, Andino, R and Baltimore, D (1994). Distinct modes of human immunodefciency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses. J Virol 68: 654-660. (Pubitemid 24022165)
-
(1994)
Journal of Virology
, vol.68
, Issue.2
, pp. 654-660
-
-
Chen, B.K.1
Saksela, K.2
Andino, R.3
Baltimore, D.4
-
23
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
DOI 10.1016/j.molcel.2004.07.007, PII S1097276504004150
-
Meister, G, Landthaler, M, Patkaniowska, A, Dorsett, Y, Teng, G and Tuschl, T (2004). Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 15: 185-197. (Pubitemid 38950966)
-
(2004)
Molecular Cell
, vol.15
, Issue.2
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
24
-
-
48349105059
-
Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
-
Zhou, J, Li, H, Li, S, Zaia, J and Rossi, JJ (2008). Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy. Mol Ther 16: 1481-1489.
-
(2008)
Mol Ther
, vol.16
, pp. 1481-1489
-
-
Zhou, J.1
Li, H.2
Li, S.3
Zaia, J.4
Rossi, J.J.5
|