Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

Biochemical and Biophysical Research Communications

Volumn 406, Issue 2, 2011, Pages 292-298

  Mercado, Nicolas ^a   Thimmulappa, Rajesh ^b   Thomas, Catherine M R ^a   Fenwick, Peter S ^a   Chana, Kirandeep K ^a   Donnelly, Louise E ^a   Biswal, Shyam ^b   Ito, Kazuhiro ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Acetylation; COPD; Histone deacetylase 2; Nrf2; Oxidative stress; Protein stability

Indexed keywords

ANTIOXIDANT; CIGARETTE SMOKE; HEME OXYGENASE 1; HISTONE DEACETYLASE 2; HYDROGEN PEROXIDE; TRANSCRIPTION FACTOR NRF2; TRICHOSTATIN A;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; BRONCHUS MUCOSA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RNA INTERFERENCE; SENSITIVITY ANALYSIS;

ACETYLATION; ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HISTONE DEACETYLASE 2; HUMANS; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEIN STABILITY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKE; SMOKING;

MUS;

EID: 79952439646     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.035     Document Type: Article

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