MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells

Journal of Biological Chemistry

Volumn 288, Issue 35, 2013, Pages 25414-25427

  Kang, Kang ^a   Peng, Xiao ^a   Zhang, Xiaoying ^a   Wang, Yuna ^a   Zhang, Lishu ^b   Gao, Li ^b   Weng, Tingting ^b   Zhang, Honghao ^b   Ramchandran, Ramaswamy ^c   Raj, J Usha ^c   Gou, Deming ^a,b,c   Liu, Lin ^b  

^a SHENZHEN UNIVERSITY   (China)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL EFFECTS; DEPHOSPHORYLATIONS; NUCLEAR FACTOR OF ACTIVATED T-CELLS; NUCLEAR TRANSLOCATIONS; PULMONARY ARTERIAL HYPERTENSION; PULMONARY ARTERY SMOOTH MUSCLE CELLS; SIGNALING PATHWAYS; TRANSACTIVATION;

GENES;

RNA;

CALMODULIN BINDING TRANSCRIPTION ACTIVATOR 1; INTERLEUKIN 2; LUCIFERASE; MICRORNA 124; POLYPYRIMIDINE TRACT BINDING PROTEIN 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CAMTA1 GENE; CELL DIFFERENTIATION; CELL NUCLEUS TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; GENE LIBRARY; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HYPOXIA; LEUKEMIA CELL LINE; MOUSE; NFAT GENE; NFATC1 GENE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PTBP1 GENE; PULMONARY ARTERY; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; REPORTER GENE; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRANSACTIVATION;

GENE REGULATION; HIGH THROUGHPUT SCREENING (HTS); IMMUNOSUPPRESSOR; MICRORNA; NFAT TRANSCRIPTION FACTOR; PULMONARY HYPERTENSION;

ANIMALS; CELL HYPOXIA; CELL PROLIFERATION; DOWN-REGULATION; HUMANS; HYPERTENSION, PULMONARY; JURKAT CELLS; MICE; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NFATC TRANSCRIPTION FACTORS; PULMONARY ARTERY; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84883426400     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.460287     Document Type: Article

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