Epigenetic regulation of mir-17∼92 contributes to the pathogenesis of pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 4, 2013, Pages 397-405

  Dakhlallah, Duaa ^a,b   Batte, Kara ^a   Wang, Yijie ^a   Cantemir Stone, Carmen Z ^a   Yan, Pearlly ^c,d   Nuovo, Gerard ^d,e   Mikhail, Adel ^e   Hitchcock, Charles L ^f   Wright, Valerie P ^a   Nana Sinkam, S Patrick ^a   Piper, Melissa G ^a   Marsh, Clay B ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b Integrative Neuroscience Program   (United States)

^c Division of Hematology   (United States)

^d Department of Internal Medicine   (United States)

^e Phylogeny Inc   (United States)

^f OHIO STATE UNIVERSITY   (United States)

Author keywords

DNA methylation; DNMT 1; microRNA; miR 17z92; Pulmonary fibrosis

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BLEOMYCIN; DNA METHYLTRANSFERASE; MICRORNA; MICRORNA 17; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FIBROBLAST; FIBROSING ALVEOLITIS; GENE EXPRESSION; GENE SILENCING; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG BIOPSY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; AZACITIDINE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENOMICS; FIBROBLASTS; GENE EXPRESSION; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MICE; MICE, INBRED C57BL; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS;

EID: 84873978112     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201205-0888OC     Document Type: Article

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