Decreased histone deacetylase activity in chronic obstructive pulmonary disease

New England Journal of Medicine

Volumn 352, Issue 19, 2005, Pages 1967-1976

  Ito, Kazuhiro ^a   Ito, Misako ^a   Elliott, W Mark ^c   Cosio, Borja ^a   Caramori, Gaetano ^d   Onn, Min Kon ^a,b   Barczyk, Adam ^e   Hayashi, Shizu ^c   Adcock, Ian M ^a   Hogg, James C ^c   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY OF FERRARA   (Italy)

^e MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 8; HISTONE H4; INTERLEUKIN 8; MESSENGER RNA; THEOPHYLLINE; UNCLASSIFIED DRUG;

ACETYLATION; ADULT; AGED; ARTICLE; ASTHMA; BRONCHUS BIOPSY; CHROMATIN; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE CLASSIFICATION; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; LUNG ALVEOLUS MACROPHAGE; LUNG PARENCHYMA; MALE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

ACETYLTRANSFERASES; AGED; ASTHMA; BLOTTING, WESTERN; BRONCHI; CHROMATIN; CYSTIC FIBROSIS; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; HUMANS; ISOENZYMES; LUNG; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SMOKING;

EID: 21044458874     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa041892     Document Type: Article

References (18)

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