-
1
-
-
33845447175
-
LOT1 (ZAC1/PLAGL1) and its family members: mechanisms and functions
-
Abdollahi A. LOT1 (ZAC1/PLAGL1) and its family members: mechanisms and functions. J. Cell. Physiol. 2007, 210:16-25.
-
(2007)
J. Cell. Physiol.
, vol.210
, pp. 16-25
-
-
Abdollahi, A.1
-
2
-
-
0034680825
-
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
-
Agani F.H., Pichiule P., Chavez J.C., LaManna J.C. The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia. J. Biol. Chem. 2000, 275:35863-35867.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35863-35867
-
-
Agani, F.H.1
Pichiule, P.2
Chavez, J.C.3
LaManna, J.C.4
-
3
-
-
43049176170
-
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
-
Akinc A., Zumbuehl A., Goldberg M., Leshchiner E.S., Busini V., Hossain N., Bacallado S.A., Nguyen D.N., Fuller J., Alvarez R., Borodovsky A., Borland T., Constien R., de Fougerolles A., Dorkin J.R., Narayanannair Jayaprakash K., Jayaraman M., John M., Koteliansky V., Manoharan M., Nechev L., Qin J., Racie T., Raitcheva D., Rajeev K.G., Sah D.W., Soutschek J., Toudjarska I., Vornlocher H.P., Zimmermann T.S., Langer R., Anderson D.G. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotechnol. 2008, 26:561-569.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 561-569
-
-
Akinc, A.1
Zumbuehl, A.2
Goldberg, M.3
Leshchiner, E.S.4
Busini, V.5
Hossain, N.6
Bacallado, S.A.7
Nguyen, D.N.8
Fuller, J.9
Alvarez, R.10
Borodovsky, A.11
Borland, T.12
Constien, R.13
de Fougerolles, A.14
Dorkin, J.R.15
Narayanannair Jayaprakash, K.16
Jayaraman, M.17
John, M.18
Koteliansky, V.19
Manoharan, M.20
Nechev, L.21
Qin, J.22
Racie, T.23
Raitcheva, D.24
Rajeev, K.G.25
Sah, D.W.26
Soutschek, J.27
Toudjarska, I.28
Vornlocher, H.P.29
Zimmermann, T.S.30
Langer, R.31
Anderson, D.G.32
more..
-
4
-
-
84911401583
-
MicroRNA-338 regulates the axonal expression of multiple nuclear-encoded mitochondrial mRNAs encoding subunits of the oxidative phosphorylation machinery
-
Aschrafi A., Kar A.N., Natera-Naranjo O., Macgibeny M.A., Gioio A.E., Kaplan B.B. MicroRNA-338 regulates the axonal expression of multiple nuclear-encoded mitochondrial mRNAs encoding subunits of the oxidative phosphorylation machinery. Cell. Mol. Life Sci. 2014, (in press).
-
(2014)
Cell. Mol. Life Sci.
-
-
Aschrafi, A.1
Kar, A.N.2
Natera-Naranjo, O.3
Macgibeny, M.A.4
Gioio, A.E.5
Kaplan, B.B.6
-
5
-
-
79960140833
-
MiR-335 and miR-34a promote renal senescence by suppressing mitochondrial antioxidative enzymes
-
Bai X.Y., Ma Y., Ding R., Fu B., Shi S., Chen X.M. miR-335 and miR-34a promote renal senescence by suppressing mitochondrial antioxidative enzymes. J. Am. Soc. Nephrol. 2011, 22:1252-1261.
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 1252-1261
-
-
Bai, X.Y.1
Ma, Y.2
Ding, R.3
Fu, B.4
Shi, S.5
Chen, X.M.6
-
6
-
-
80053020472
-
Mitochondria as novel players of the cellular RNA interference
-
Bandiera S., Hanein S., Lyonnet S., Henrion-Caude A. Mitochondria as novel players of the cellular RNA interference. J. Biol. Chem. 2011, 286:le19.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. le19
-
-
Bandiera, S.1
Hanein, S.2
Lyonnet, S.3
Henrion-Caude, A.4
-
7
-
-
79958737573
-
Nuclear outsourcing of RNA interference components to human mitochondria
-
Bandiera S., Rüberg S., Girard M., Cagnard N., Hanein S., Chrétien D., Munnich A., Lyonnet S., Henrion-Caude A. Nuclear outsourcing of RNA interference components to human mitochondria. PLoS One 2011, 6:e20746.
-
(2011)
PLoS One
, vol.6
, pp. e20746
-
-
Bandiera, S.1
Rüberg, S.2
Girard, M.3
Cagnard, N.4
Hanein, S.5
Chrétien, D.6
Munnich, A.7
Lyonnet, S.8
Henrion-Caude, A.9
-
8
-
-
84885187303
-
MitomiRs delineating the intracellular localization of microRNAs at mitochondria
-
Bandiera S., Matégot R., Girard M., Demongeot J., Henrion-Caude A. MitomiRs delineating the intracellular localization of microRNAs at mitochondria. Free Radic. Biol. Med. 2013, 64:12-19.
-
(2013)
Free Radic. Biol. Med.
, vol.64
, pp. 12-19
-
-
Bandiera, S.1
Matégot, R.2
Girard, M.3
Demongeot, J.4
Henrion-Caude, A.5
-
9
-
-
79957575344
-
Pre-microRNA and mature microRNA in human mitochondria
-
Barrey E., Saint-Auret G., Bonnamy B., Damas D., Boyer O., Gidrol X. Pre-microRNA and mature microRNA in human mitochondria. PLoS One 2011, 6:e20220.
-
(2011)
PLoS One
, vol.6
, pp. e20220
-
-
Barrey, E.1
Saint-Auret, G.2
Bonnamy, B.3
Damas, D.4
Boyer, O.5
Gidrol, X.6
-
10
-
-
30544433533
-
ATP citrate lyase is an important component of cell growth and transformation
-
Bauer D.E., Hatzivassiliou G., Zhao F., Andreadis C., Thompson C.B. ATP citrate lyase is an important component of cell growth and transformation. Oncogene 2005, 24:6314-6322.
-
(2005)
Oncogene
, vol.24
, pp. 6314-6322
-
-
Bauer, D.E.1
Hatzivassiliou, G.2
Zhao, F.3
Andreadis, C.4
Thompson, C.B.5
-
11
-
-
77953812057
-
Multi-site control and regulation of mitochondrial energy production
-
Benard G., Bellance N., Jose C., Melser S., Nouette-Gaulain K., Rossignol R. Multi-site control and regulation of mitochondrial energy production. Biochim. Biophys. Acta 2010, 1797:698-709.
-
(2010)
Biochim. Biophys. Acta
, vol.1797
, pp. 698-709
-
-
Benard, G.1
Bellance, N.2
Jose, C.3
Melser, S.4
Nouette-Gaulain, K.5
Rossignol, R.6
-
13
-
-
77956343851
-
Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions
-
Bian Z., Li L.M., Tang R., Hou D.X., Chen X., Zhang C.Y., Zen K. Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions. Cell Res. 2010, 20:1076-1078.
-
(2010)
Cell Res.
, vol.20
, pp. 1076-1078
-
-
Bian, Z.1
Li, L.M.2
Tang, R.3
Hou, D.X.4
Chen, X.5
Zhang, C.Y.6
Zen, K.7
-
14
-
-
34547458550
-
P53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
Bommer G.T., Gerin I., Feng Y., Kaczorowski A.J., Kuick R., Love R.E., Zhai Y., Giordano T.J., Qin Z.S., Moore B.B., MacDougald O.A., Cho K.R., Fearon E.R. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr. Biol. 2007, 17:1298-1307.
-
(2007)
Curr. Biol.
, vol.17
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
Kaczorowski, A.J.4
Kuick, R.5
Love, R.E.6
Zhai, Y.7
Giordano, T.J.8
Qin, Z.S.9
Moore, B.B.10
MacDougald, O.A.11
Cho, K.R.12
Fearon, E.R.13
-
16
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin G.A., Sevignani C., Dumitru C.D., Hyslop T., Noch E., Yendamuri S., Shimizu M., Rattan S., Bullrich F., Negrini M., Croce C.M. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:2999-3000.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2999-3000
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
Croce, C.M.11
-
17
-
-
77950799838
-
MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis
-
Cha S.T., Chen P.S., Johansson G., Chu C.Y., Wang M.Y., Jeng Y.M., Yu S.L., Chen J.S., Chang K.J., Jee S.H., Tan C.T., Lin M.T., Kuo M.L. MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis. Cancer Res. 2010, 70:2675-2685.
-
(2010)
Cancer Res.
, vol.70
, pp. 2675-2685
-
-
Cha, S.T.1
Chen, P.S.2
Johansson, G.3
Chu, C.Y.4
Wang, M.Y.5
Jeng, Y.M.6
Yu, S.L.7
Chen, J.S.8
Chang, K.J.9
Jee, S.H.10
Tan, C.T.11
Lin, M.T.12
Kuo, M.L.13
-
18
-
-
77953483108
-
MicroRNA-210: A unique and pleiotropic hypoxamir
-
Chan S.Y., Loscalzo J. MicroRNA-210: A unique and pleiotropic hypoxamir. Cell Cycle 2010, 9:1072-1083.
-
(2010)
Cell Cycle
, vol.9
, pp. 1072-1083
-
-
Chan, S.Y.1
Loscalzo, J.2
-
19
-
-
79955649353
-
Cancer microRNAs: From subtype profiling to predictors of response to therapy
-
Chan E., Prado D.E., Weidhaas J.B. Cancer microRNAs: From subtype profiling to predictors of response to therapy. Trends Mol. Med. 2011, 17:235-243.
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 235-243
-
-
Chan, E.1
Prado, D.E.2
Weidhaas, J.B.3
-
20
-
-
70349478990
-
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
-
Chan S.Y., Zhang Y.Y., Hemann C., Mahoney C.E., Zweier J.L., Loscalzo J. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 2012, 10:273-284.
-
(2012)
Cell Metab.
, vol.10
, pp. 273-284
-
-
Chan, S.Y.1
Zhang, Y.Y.2
Hemann, C.3
Mahoney, C.E.4
Zweier, J.L.5
Loscalzo, J.6
-
21
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel N.S., Maltepe E., Goldwasser E., Mathieu C.E., Simon M.C., Schumacker P.T. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:11715-11720.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
22
-
-
0034682786
-
2 sensing
-
2 sensing. J. Biol. Chem. 2000, 275:25130-25138.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Wood, T.M.4
Melendez, J.A.5
Rodriguez, A.M.6
Schumacker, P.T.7
-
23
-
-
84899481430
-
Post-transcriptional gene regulation by HuR and microRNAs in angiogenesis
-
Chang S.H., Hla T. Post-transcriptional gene regulation by HuR and microRNAs in angiogenesis. Curr. Opin. Hematol. 2014, 21:235-240.
-
(2014)
Curr. Opin. Hematol.
, vol.21
, pp. 235-240
-
-
Chang, S.H.1
Hla, T.2
-
24
-
-
84906086597
-
Activation of PI3K/Akt/MTOR pathway and dual inhibitors of PI3K and MTOR in endometrial cancer
-
Chen J., Zhao K.N., Li R., Shao R., Chen C. Activation of PI3K/Akt/MTOR pathway and dual inhibitors of PI3K and MTOR in endometrial cancer. Curr. Med. Chem. 2014, (in press).
-
(2014)
Curr. Med. Chem.
-
-
Chen, J.1
Zhao, K.N.2
Li, R.3
Shao, R.4
Chen, C.5
-
25
-
-
84863661689
-
Therapeutic targets in cancer cell metabolism and autophagy
-
Cheong H., Lu C., Lindsten T., Thompson C.B. Therapeutic targets in cancer cell metabolism and autophagy. Nat. Biotechnol. 2012, 30:671-678.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 671-678
-
-
Cheong, H.1
Lu, C.2
Lindsten, T.3
Thompson, C.B.4
-
26
-
-
84877599439
-
Tumor hypoxia and metabolism - towards novel anticancer approaches
-
Chiche J., Ricci J.E., Pouysségur J. Tumor hypoxia and metabolism - towards novel anticancer approaches. Ann. Endocrinol. 2013, 74:111-114.
-
(2013)
Ann. Endocrinol.
, vol.74
, pp. 111-114
-
-
Chiche, J.1
Ricci, J.E.2
Pouysségur, J.3
-
27
-
-
84858975779
-
The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies
-
Corsini L.R., Bronte G., Terrasi M., Amodeo V., Fanale D., Fiorentino E., Cicero G., Bazan V., Russo A. The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies. Expert Opin. Ther. Targets 2012, 16:S103-S109.
-
(2012)
Expert Opin. Ther. Targets
, vol.16
, pp. S103-S109
-
-
Corsini, L.R.1
Bronte, G.2
Terrasi, M.3
Amodeo, V.4
Fanale, D.5
Fiorentino, E.6
Cicero, G.7
Bazan, V.8
Russo, A.9
-
28
-
-
37549032776
-
The interplay between MYC and HIF in cancer
-
Dang C.V., Kim J.W., Gao P., Yustein J. The interplay between MYC and HIF in cancer. Nat. Rev. Cancer 2008, 8:51-56.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 51-56
-
-
Dang, C.V.1
Kim, J.W.2
Gao, P.3
Yustein, J.4
-
29
-
-
84862279805
-
Nuclear miRNA regulates the mitochondrial genome in the heart
-
Das S., Ferlito M., Kent O.A., Fox-Talbot K., Wang R., Liu D., Raghavachari N., Yang Y., Wheelan S.J., Murphy E., Steenbergen C. Nuclear miRNA regulates the mitochondrial genome in the heart. Circ. Res. 2012, 110:1596-1603.
-
(2012)
Circ. Res.
, vol.110
, pp. 1596-1603
-
-
Das, S.1
Ferlito, M.2
Kent, O.A.3
Fox-Talbot, K.4
Wang, R.5
Liu, D.6
Raghavachari, N.7
Yang, Y.8
Wheelan, S.J.9
Murphy, E.10
Steenbergen, C.11
-
31
-
-
77955264991
-
Designing small multiple-target artificial RNAs
-
De Guire V., Caron M., Scott N., Ménard C., Gaumont-Leclerc M.F., Chartrand P., Major F., Ferbeyre G. Designing small multiple-target artificial RNAs. Nucleic Acids Res. 2010, 38:e140.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. e140
-
-
De Guire, V.1
Caron, M.2
Scott, N.3
Ménard, C.4
Gaumont-Leclerc, M.F.5
Chartrand, P.6
Major, F.7
Ferbeyre, G.8
-
32
-
-
84884813844
-
MitomiRs, chloromiRs and modelling of the microRNA inhibition
-
Demongeot J., Hazgui H., Bandiera S., Cohen O., Henrion-Caude A. MitomiRs, chloromiRs and modelling of the microRNA inhibition. Acta Biotheor. 2013, 61:367-383.
-
(2013)
Acta Biotheor.
, vol.61
, pp. 367-383
-
-
Demongeot, J.1
Hazgui, H.2
Bandiera, S.3
Cohen, O.4
Henrion-Caude, A.5
-
33
-
-
79952137486
-
MiR-210: More than a silent player in hypoxia
-
Devlin C., Greco S., Martelli F., Ivan M. miR-210: More than a silent player in hypoxia. IUBMB Life 2011, 63:94-100.
-
(2011)
IUBMB Life
, vol.63
, pp. 94-100
-
-
Devlin, C.1
Greco, S.2
Martelli, F.3
Ivan, M.4
-
34
-
-
84883514161
-
Targeting lactate metabolism for cancer therapeutics
-
Doherty J.R., Cleveland J.L. Targeting lactate metabolism for cancer therapeutics. J. Clin. Invest. 2013, 123:3685-3692.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3685-3692
-
-
Doherty, J.R.1
Cleveland, J.L.2
-
35
-
-
45549090182
-
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
-
Dong X.C., Copps K.D., Guo S., Li Y., Kollipara R., De Pinho R.A., White M.F. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab. 2008, 8:65-76.
-
(2008)
Cell Metab.
, vol.8
, pp. 65-76
-
-
Dong, X.C.1
Copps, K.D.2
Guo, S.3
Li, Y.4
Kollipara, R.5
De Pinho, R.A.6
White, M.F.7
-
36
-
-
84883488437
-
MicroRNAs and metabolism crosstalk in energy homeostasis
-
Dumortier O., Hinault C., Van Obberghen E. MicroRNAs and metabolism crosstalk in energy homeostasis. Cell Metab. 2013, 18:312-324.
-
(2013)
Cell Metab.
, vol.18
, pp. 312-324
-
-
Dumortier, O.1
Hinault, C.2
Van Obberghen, E.3
-
37
-
-
34548316982
-
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
-
Ebert M.S., Neilson J.R., Sharp P.A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 2007, 4:721-726.
-
(2007)
Nat. Methods
, vol.4
, pp. 721-726
-
-
Ebert, M.S.1
Neilson, J.R.2
Sharp, P.A.3
-
38
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom R.L., Bauer D.E., Buzzai M., Karnauskas R., Harris M.H., Plas D.R., Zhuang H., Cinalli R.M., Alavi A., Rudin C.M., Thompson C.B. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 2004, 64:3892-3899.
-
(2004)
Cancer Res.
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
Thompson, C.B.11
-
39
-
-
33645294070
-
Oncomirs - microRNAs with a role in cancer
-
Esquela-Kerscher A., Slack F.J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6:259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
40
-
-
84863316020
-
MicroRNA-143 (miR-143) regulates cancer glycolysis via targeting hexokinase 2 gene
-
Fang R., Xiao T., Fang Z., Sun Y., Li F., Gao Y., Feng Y., Li L., Wang Y., Liu X., Chen H., Liu X.Y., Ji H. MicroRNA-143 (miR-143) regulates cancer glycolysis via targeting hexokinase 2 gene. J. Biol. Chem. 2012, 287:23227-23235.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23227-23235
-
-
Fang, R.1
Xiao, T.2
Fang, Z.3
Sun, Y.4
Li, F.5
Gao, Y.6
Feng, Y.7
Li, L.8
Wang, Y.9
Liu, X.10
Chen, H.11
Liu, X.Y.12
Ji, H.13
-
41
-
-
77956402239
-
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
-
Favaro E., Ramachandran A., McCormick R., Gee H., Blancher C., Crosby M., Devlin C., Blick C., Buffa F., Li J.L., Vojnovic B., Pires das Neves R., Glazer P., Iborra F., Ivan M., Ragoussis J., Harris A.L. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One 2010, 5:e10345.
-
(2010)
PLoS One
, vol.5
, pp. e10345
-
-
Favaro, E.1
Ramachandran, A.2
McCormick, R.3
Gee, H.4
Blancher, C.5
Crosby, M.6
Devlin, C.7
Blick, C.8
Buffa, F.9
Li, J.L.10
Vojnovic, B.11
Pires das Neves, R.12
Glazer, P.13
Iborra, F.14
Ivan, M.15
Ragoussis, J.16
Harris, A.L.17
-
42
-
-
84862784999
-
MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression
-
Fei X., Qi M., Wu B., Song Y., Wang Y., Li T. MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. FEBS Lett. 2012, 586:392-397.
-
(2012)
FEBS Lett.
, vol.586
, pp. 392-397
-
-
Fei, X.1
Qi, M.2
Wu, B.3
Song, Y.4
Wang, Y.5
Li, T.6
-
43
-
-
77956915352
-
MiR-126 functions as a tumour suppressor in human gastric cancer
-
Feng R., Chen X., Yu Y., Su L., Yu B., Li J., Cai Q., Yan M., Liu B., Zhu Z. MiR-126 functions as a tumour suppressor in human gastric cancer. Cancer Lett. 2010, 298:50-63.
-
(2010)
Cancer Lett.
, vol.298
, pp. 50-63
-
-
Feng, R.1
Chen, X.2
Yu, Y.3
Su, L.4
Yu, B.5
Li, J.6
Cai, Q.7
Yan, M.8
Liu, B.9
Zhu, Z.10
-
44
-
-
84865313576
-
Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
-
Filipp F.V., Scott D.A., Ronai Z.A., Osterman A.L., Smith J.W. Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells. Pigment Cell Melanoma Res. 2012, 25:375-383.
-
(2012)
Pigment Cell Melanoma Res.
, vol.25
, pp. 375-383
-
-
Filipp, F.V.1
Scott, D.A.2
Ronai, Z.A.3
Osterman, A.L.4
Smith, J.W.5
-
45
-
-
84875354450
-
In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation
-
Gameiro P.A., Yang J., Metelo A.M., Pérez-Carro R., Baker R., Wang Z., Arreola A., Rathme W.K., Olumi A., López-Larrubia P., Stephanopoulos G., Iliopoulos O. In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation. Cell Metab. 2013, 17:372-385.
-
(2013)
Cell Metab.
, vol.17
, pp. 372-385
-
-
Gameiro, P.A.1
Yang, J.2
Metelo, A.M.3
Pérez-Carro, R.4
Baker, R.5
Wang, Z.6
Arreola, A.7
Rathme, W.K.8
Olumi, A.9
López-Larrubia, P.10
Stephanopoulos, G.11
Iliopoulos, O.12
-
46
-
-
84864573730
-
MicroRNAs and the Warburg Effect: new players in an old arena
-
Gao P., Sun L., He X., Cao Y., Zhang H. MicroRNAs and the Warburg Effect: new players in an old arena. Curr. Gene Ther. 2012, 12:285-291.
-
(2012)
Curr. Gene Ther.
, vol.12
, pp. 285-291
-
-
Gao, P.1
Sun, L.2
He, X.3
Cao, Y.4
Zhang, H.5
-
47
-
-
67049096242
-
Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells
-
Ghosh A.K., Shanafelt T.D., Cimmino A., Taccioli C., Volinia S., Liu C.G., Calin G.A., Croce C.M., Chan D.A., Giaccia A.J., Secreto C., Wellik L.E., Lee Y.K., Mukhopadhyay D., Kay N.E. Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells. Blood 2009, 113:5568-5574.
-
(2009)
Blood
, vol.113
, pp. 5568-5574
-
-
Ghosh, A.K.1
Shanafelt, T.D.2
Cimmino, A.3
Taccioli, C.4
Volinia, S.5
Liu, C.G.6
Calin, G.A.7
Croce, C.M.8
Chan, D.A.9
Giaccia, A.J.10
Secreto, C.11
Wellik, L.E.12
Lee, Y.K.13
Mukhopadhyay, D.14
Kay, N.E.15
-
48
-
-
78049424494
-
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
-
Ghosh G., Subramanian I.V., Adhikari N., Zhang X., Joshi H.P., Basi D., Chandrashekhar Y.S., Hall J.L., Roy S., Zeng Y., Ramakrishnan S. Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J. Clin. Invest. 2010, 120:4141-4154.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4141-4154
-
-
Ghosh, G.1
Subramanian, I.V.2
Adhikari, N.3
Zhang, X.4
Joshi, H.P.5
Basi, D.6
Chandrashekhar, Y.S.7
Hall, J.L.8
Roy, S.9
Zeng, Y.10
Ramakrishnan, S.11
-
49
-
-
34047234959
-
Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis
-
Gibson S.L., Ma Z., Shaw L.M. Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis. Cell Cycle 2007, 6:631-637.
-
(2007)
Cell Cycle
, vol.6
, pp. 631-637
-
-
Gibson, S.L.1
Ma, Z.2
Shaw, L.M.3
-
50
-
-
56849096837
-
HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
-
Gordan J.D., Lal P., Dondeti V.R., Letrero R., Parekh K.N., Oquendo C.E., Greenberg R.A., Flaherty K.T., Rathmell W.K., Keith B., Simon M.C., Nathanson K.L. HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell 2008, 14:435-446.
-
(2008)
Cancer Cell
, vol.14
, pp. 435-446
-
-
Gordan, J.D.1
Lal, P.2
Dondeti, V.R.3
Letrero, R.4
Parekh, K.N.5
Oquendo, C.E.6
Greenberg, R.A.7
Flaherty, K.T.8
Rathmell, W.K.9
Keith, B.10
Simon, M.C.11
Nathanson, K.L.12
-
51
-
-
84871122805
-
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells
-
Gregersen L.H., Jacobsen A., Frankel L.B., Wen J., Krogh A., Lund A.H. MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells. BMC Cancer 2012, 12:232.
-
(2012)
BMC Cancer
, vol.12
, pp. 232
-
-
Gregersen, L.H.1
Jacobsen, A.2
Frankel, L.B.3
Wen, J.4
Krogh, A.5
Lund, A.H.6
-
52
-
-
54749089002
-
Small-molecule inhibitors of microrna miR-21 function
-
Gumireddy K., Young D.D., Xiong X., Hogenesch J.B., Huang Q., Deiters A. Small-molecule inhibitors of microrna miR-21 function. Angew. Chem. Int. Ed. Engl. 2008, 47:7482-7484.
-
(2008)
Angew. Chem. Int. Ed. Engl.
, vol.47
, pp. 7482-7484
-
-
Gumireddy, K.1
Young, D.D.2
Xiong, X.3
Hogenesch, J.B.4
Huang, Q.5
Deiters, A.6
-
53
-
-
52249096359
-
The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
-
Guo C., Sah J.F., Beard L., Willson J.K., Markowitz S.D., Guda K. The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Gene Chromosome Cancer 2008, 47:939-946.
-
(2008)
Gene Chromosome Cancer
, vol.47
, pp. 939-946
-
-
Guo, C.1
Sah, J.F.2
Beard, L.3
Willson, J.K.4
Markowitz, S.D.5
Guda, K.6
-
54
-
-
70249108137
-
The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis
-
Guo S., Copps K.D., Dong X., Park S., Cheng Z., Pocai A., Rossetti L., Sajan M., Farese R.V., White M.F. The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Mol. Cell. Biol. 2009, 29:5070-5083.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5070-5083
-
-
Guo, S.1
Copps, K.D.2
Dong, X.3
Park, S.4
Cheng, Z.5
Pocai, A.6
Rossetti, L.7
Sajan, M.8
Farese, R.V.9
White, M.F.10
-
55
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
56
-
-
84883742865
-
MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial
-
Hansen T.F., Christensen R.D., Andersen R.F., Sørensen F.B., Johnsson A., Jakobsen A. MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial. Br. J. Cancer 2013, 109:1243-1251.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 1243-1251
-
-
Hansen, T.F.1
Christensen, R.D.2
Andersen, R.F.3
Sørensen, F.B.4
Johnsson, A.5
Jakobsen, A.6
-
57
-
-
84864663987
-
MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells
-
Haque R., Chun E., Howell J.C., Sengupta T., Chen D., Kim H. MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells. PLoS One 2012, 7:e42542.
-
(2012)
PLoS One
, vol.7
, pp. e42542
-
-
Haque, R.1
Chun, E.2
Howell, J.C.3
Sengupta, T.4
Chen, D.5
Kim, H.6
-
58
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou G., Zhao F., Bauer D.E., Andreadis C., Shaw A.N., Dhanak D., Hingorani S.R., Tuveson D.A., Thompson C.B. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 2005, 8:311-321.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
59
-
-
70349309314
-
MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes
-
Horie T., Ono K., Nishi H., Iwanaga Y., Nagao K., Kinoshita M., Kuwabara Y., Takanabe R., Hasegawa K., Kita T., Kimura T. MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes. Biochem. Biophys. Res. Commun. 2009, 389:315-320.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, pp. 315-320
-
-
Horie, T.1
Ono, K.2
Nishi, H.3
Iwanaga, Y.4
Nagao, K.5
Kinoshita, M.6
Kuwabara, Y.7
Takanabe, R.8
Hasegawa, K.9
Kita, T.10
Kimura, T.11
-
60
-
-
40949108800
-
Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation
-
Huang L.E. Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation. Cell Death Differ. 2008, 15:672-677.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 672-677
-
-
Huang, L.E.1
-
61
-
-
84904263339
-
Repression of miR-126 and upregulation of adrenomedullin in the stromal endothelium by cancer-stromal cross talks confers angiogenesis of cervical cancer
-
Huang T.H., Chu T.Y. Repression of miR-126 and upregulation of adrenomedullin in the stromal endothelium by cancer-stromal cross talks confers angiogenesis of cervical cancer. Oncogene 2014, (in press).
-
(2014)
Oncogene
-
-
Huang, T.H.1
Chu, T.Y.2
-
62
-
-
77952111459
-
MiR-210-micromanager of the hypoxia pathway
-
Huang X., Le Q.T., Giaccia A.J. MiR-210-micromanager of the hypoxia pathway. Trends Mol. Med. 2010, 16:230-237.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 230-237
-
-
Huang, X.1
Le, Q.T.2
Giaccia, A.J.3
-
63
-
-
84862243555
-
Causes and consequences of microRNA dysregulation
-
Iorio M.V., Croce C.M. Causes and consequences of microRNA dysregulation. Cancer J. 2012, 18:215-222.
-
(2012)
Cancer J.
, vol.18
, pp. 215-222
-
-
Iorio, M.V.1
Croce, C.M.2
-
64
-
-
84902765817
-
The effects of environmental chemical carcinogens on the microRNA machinery
-
Izzotti A., Pulliero A. The effects of environmental chemical carcinogens on the microRNA machinery. Int. J. Hyg. Environ. Health 2014, 217(6):601-627.
-
(2014)
Int. J. Hyg. Environ. Health
, vol.217
, Issue.6
, pp. 601-627
-
-
Izzotti, A.1
Pulliero, A.2
-
65
-
-
82755189770
-
Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung
-
Izzotti A., Larghero P., Longobardi M., Cartiglia C., Camoirano A., Steele V.E., De Flora S. Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung. Mutat. Res. 2011, 717:9-16.
-
(2011)
Mutat. Res.
, vol.717
, pp. 9-16
-
-
Izzotti, A.1
Larghero, P.2
Longobardi, M.3
Cartiglia, C.4
Camoirano, A.5
Steele, V.E.6
De Flora, S.7
-
66
-
-
84880476558
-
The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational epression of IRS-1 in SK-Hep1 cells
-
Jeong H.J., Park S.Y., Yang W.M., Lee W. The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational epression of IRS-1 in SK-Hep1 cells. Biochem. Biophys. Res. Commun. 2013, 434:503-508.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.434
, pp. 503-508
-
-
Jeong, H.J.1
Park, S.Y.2
Yang, W.M.3
Lee, W.4
-
67
-
-
84862812020
-
A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells
-
Jiang S., Zhang L.F., Zhang H.W., Hu S., Lu M.H., Liang S., Li B., Li Y., Li D., Wang E.D., Liu M.F. A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. EMBO J. 2012, 3:1985-1998.
-
(2012)
EMBO J.
, vol.3
, pp. 1985-1998
-
-
Jiang, S.1
Zhang, L.F.2
Zhang, H.W.3
Hu, S.4
Lu, M.H.5
Liang, S.6
Li, B.7
Li, Y.8
Li, D.9
Wang, E.D.10
Liu, M.F.11
-
68
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson S.M., Grosshans H., Shingara J., Byrom M., Jarvis R., Cheng A., Labourier E., Reinert K.L., Brown D., Slack F.J. RAS is regulated by the let-7 microRNA family. Cell 2005, 120:635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
69
-
-
84859927971
-
Tumour cell-derived exosomes: a message in a bottle
-
Kharaziha P., Ceder S., Li Q., Panaretakis T. Tumour cell-derived exosomes: a message in a bottle. Biochim. Biophys. Acta 2012, 1826:103-111.
-
(2012)
Biochim. Biophys. Acta
, vol.1826
, pp. 103-111
-
-
Kharaziha, P.1
Ceder, S.2
Li, Q.3
Panaretakis, T.4
-
70
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
-
Kim J.W., Tchernyshyov I., Semenza G.L., Dang C.V. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006, 3:177-185.
-
(2006)
Cell Metab.
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
71
-
-
40949126440
-
Mitochondrial complex III regulates hypoxic activation of HIF
-
Klimova T., Chandel N.S. Mitochondrial complex III regulates hypoxic activation of HIF. Cell Death Differ. 2008, 15:660-666.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 660-666
-
-
Klimova, T.1
Chandel, N.S.2
-
72
-
-
33947520506
-
Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF
-
Koivunen P., Hirsilä M., Remes A.M., Hassinen I.E., Kivirikko K.I., Myllyharju J. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. J. Biol. Chem. 2007, 282:4524-4532.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4524-4532
-
-
Koivunen, P.1
Hirsilä, M.2
Remes, A.M.3
Hassinen, I.E.4
Kivirikko, K.I.5
Myllyharju, J.6
-
73
-
-
0036528246
-
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
-
Kondo K., Klco J., Nakamura E., Lechpammer M., Kaelin W.G. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 2002, 1:237-246.
-
(2002)
Cancer Cell
, vol.1
, pp. 237-246
-
-
Kondo, K.1
Klco, J.2
Nakamura, E.3
Lechpammer, M.4
Kaelin, W.G.5
-
74
-
-
84886040203
-
Trash or treasure: extracellular microRNAs and cell-to-cell communication
-
Kosaka N., Yoshioka Y., Hagiwara K., Tominaga N., Katsuda T., Ochiya T. Trash or treasure: extracellular microRNAs and cell-to-cell communication. Front. Genet. 2013, 4:173.
-
(2013)
Front. Genet.
, vol.4
, pp. 173
-
-
Kosaka, N.1
Yoshioka, Y.2
Hagiwara, K.3
Tominaga, N.4
Katsuda, T.5
Ochiya, T.6
-
75
-
-
62549157379
-
MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis
-
Kren B.T., Wong P.Y., Sarver A., Zhang X., Zeng Y., Steer C.J. MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis. RNA Biol. 2009, 6:65-72.
-
(2009)
RNA Biol.
, vol.6
, pp. 65-72
-
-
Kren, B.T.1
Wong, P.Y.2
Sarver, A.3
Zhang, X.4
Zeng, Y.5
Steer, C.J.6
-
76
-
-
33847234988
-
A microRNA signature of hypoxia
-
Kulshreshtha R., Ferracin M., Wojcik S.E., Garzon R., Alder H., Agosto-Perez F.J., Davuluri R., Liu C.G., Croce C.M., Negrini M., Calin G.A., Ivan M. A microRNA signature of hypoxia. Mol. Cell. Biol. 2007, 27:1859-1867.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1859-1867
-
-
Kulshreshtha, R.1
Ferracin, M.2
Wojcik, S.E.3
Garzon, R.4
Alder, H.5
Agosto-Perez, F.J.6
Davuluri, R.7
Liu, C.G.8
Croce, C.M.9
Negrini, M.10
Calin, G.A.11
Ivan, M.12
-
77
-
-
34547134517
-
Hypoxia-inducible factor 1 alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
-
Land S.C., Tee A.R. Hypoxia-inducible factor 1 alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. J. Biol. Chem. 2007, 282:20534-20543.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20534-20543
-
-
Land, S.C.1
Tee, A.R.2
-
78
-
-
70449602451
-
Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration
-
Lei Z., Li B., Yang Z., Fang H., Zhang G.M., Feng Z.H., Huang B. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One 2009, 4:e7629.
-
(2009)
PLoS One
, vol.4
, pp. e7629
-
-
Lei, Z.1
Li, B.2
Yang, Z.3
Fang, H.4
Zhang, G.M.5
Feng, Z.H.6
Huang, B.7
-
79
-
-
84857546393
-
Control of mitochondrial activity by miRNAs
-
Li P., Jiao J., Gao G., Prabhakar B.S. Control of mitochondrial activity by miRNAs. J. Cell. Biochem. 2012, 113:1104-1110.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 1104-1110
-
-
Li, P.1
Jiao, J.2
Gao, G.3
Prabhakar, B.S.4
-
80
-
-
84866515571
-
MicroRNA-145 protects cardiomyocytes against hydrogen heroxide-induced apoptosis through targeting the mitochondria apoptotic pathway
-
Li R., Yan G., Li Q., Sun H., Hu Y., Sun J., Xu B. MicroRNA-145 protects cardiomyocytes against hydrogen heroxide-induced apoptosis through targeting the mitochondria apoptotic pathway. PLoS One 2012, 7:e44907.
-
(2012)
PLoS One
, vol.7
, pp. e44907
-
-
Li, R.1
Yan, G.2
Li, Q.3
Sun, H.4
Hu, Y.5
Sun, J.6
Xu, B.7
-
81
-
-
84894521534
-
Epigenetic silencing of MicroRNA-503 regulates FANCA expression in non-small cell lung cancer cell
-
Li N., Zhang F., Li S., Zhou S. Epigenetic silencing of MicroRNA-503 regulates FANCA expression in non-small cell lung cancer cell. Biochem. Biophys. Res. Commun. 2014, 444(4):611-666.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.444
, Issue.4
, pp. 611-666
-
-
Li, N.1
Zhang, F.2
Li, S.3
Zhou, S.4
-
83
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert B.L., Mak R.H., Ferrando A.A., Downing J.R., Jacks T., Horvitz H.R., Golub T.R. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
84
-
-
84920166969
-
The Warburg effect in tumour progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism
-
Lu J., Tan M., Cai Q. The Warburg effect in tumour progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism. Cancer Lett. 2014, (in press).
-
(2014)
Cancer Lett.
-
-
Lu, J.1
Tan, M.2
Cai, Q.3
-
85
-
-
77954051861
-
The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors
-
Mancarelli M.M., Zazzeroni F., Ciccocioppo L., Capece D., Po A., Murgo S., Di Camillo R., Rinaldi C., Ferretti E., Gulino A., Alesse E. The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors. Mol. Cancer 2010, 9:172.
-
(2010)
Mol. Cancer
, vol.9
, pp. 172
-
-
Mancarelli, M.M.1
Zazzeroni, F.2
Ciccocioppo, L.3
Capece, D.4
Po, A.5
Murgo, S.6
Di Camillo, R.7
Rinaldi, C.8
Ferretti, E.9
Gulino, A.10
Alesse, E.11
-
86
-
-
21844449964
-
Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein
-
Maniataki E., Mourelatos Z. Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein. RNA 2005, 11:849-852.
-
(2005)
RNA
, vol.11
, pp. 849-852
-
-
Maniataki, E.1
Mourelatos, Z.2
-
87
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999, 399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
88
-
-
84861962359
-
Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1
-
Meng S., Cao J.T., Zhang B., Zhou Q., Shen C.X., Wang C.Q. Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1. J. Mol. Cell. Cardiol. 2012, 53:64-72.
-
(2012)
J. Mol. Cell. Cardiol.
, vol.53
, pp. 64-72
-
-
Meng, S.1
Cao, J.T.2
Zhang, B.3
Zhou, Q.4
Shen, C.X.5
Wang, C.Q.6
-
89
-
-
80052007901
-
The human mitochondrial transcriptome
-
Mercer T.R., Neph S., Dinger M.E., Crawford J., Smith M.A., Shearwood A.M., Haugen E., Bracken C.P., Rackham O., Stamatoyannopoulos J.A., Filipovska A., Mattick J.S. The human mitochondrial transcriptome. Cell 2011, 146:645-658.
-
(2011)
Cell
, vol.146
, pp. 645-658
-
-
Mercer, T.R.1
Neph, S.2
Dinger, M.E.3
Crawford, J.4
Smith, M.A.5
Shearwood, A.M.6
Haugen, E.7
Bracken, C.P.8
Rackham, O.9
Stamatoyannopoulos, J.A.10
Filipovska, A.11
Mattick, J.S.12
-
90
-
-
84855987831
-
Reductive carboxylation supports growth in tumour cells with defective mitochondria
-
Mullen A.R., Wheaton W.W., Jin E.S., Chen P.H., Sullivan L.B., Cheng T., Yang Y., Linehan W.M., Chandel N.S., DeBerardinis R.J. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature 2011, 481:385-388.
-
(2011)
Nature
, vol.481
, pp. 385-388
-
-
Mullen, A.R.1
Wheaton, W.W.2
Jin, E.S.3
Chen, P.H.4
Sullivan, L.B.5
Cheng, T.6
Yang, Y.7
Linehan, W.M.8
Chandel, N.S.9
DeBerardinis, R.J.10
-
91
-
-
80053259947
-
MicroRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects
-
Mutharasan R.K., Nagpal V., Ichikawa Y., Ardehali H. microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects. Am. J. Physiol. 2011, 301:H1519-H1530.
-
(2011)
Am. J. Physiol.
, vol.301
, pp. H1519-H1530
-
-
Mutharasan, R.K.1
Nagpal, V.2
Ichikawa, Y.3
Ardehali, H.4
-
92
-
-
84858376953
-
Mitochondria: in sickness and in health
-
Nunnari J., Suomalainen A. Mitochondria: in sickness and in health. Cell 2012, 148:1145-1159.
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
94
-
-
33846630894
-
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
-
Pan Y., Mansfield K.D., Bertozzi C.C., Rudenko V., Chan D.A., Giaccia A.J., Simon M.C. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. Mol. Cell. Biol. 2007, 27:912-925.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 912-925
-
-
Pan, Y.1
Mansfield, K.D.2
Bertozzi, C.C.3
Rudenko, V.4
Chan, D.A.5
Giaccia, A.J.6
Simon, M.C.7
-
95
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou I., Cairns R.A., Fontana L., Lim A.L., Denko N.C. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3:187-197.
-
(2006)
Cell Metab.
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
96
-
-
84873708461
-
MiR-143 regulates hexokinase 2 expression in cancer cells
-
Peschiaroli A., Giacobbe A., Formosa A., Markert E.K., Bongiorno-Borbone L., Levine A.J., Candi E., D'Alessandro A., Zolla L., Finazzi Agrò A., Melino G. miR-143 regulates hexokinase 2 expression in cancer cells. Oncogene 2013, 32:797-802.
-
(2013)
Oncogene
, vol.32
, pp. 797-802
-
-
Peschiaroli, A.1
Giacobbe, A.2
Formosa, A.3
Markert, E.K.4
Bongiorno-Borbone, L.5
Levine, A.J.6
Candi, E.7
D'Alessandro, A.8
Zolla, L.9
Finazzi Agrò, A.10
Melino, G.11
-
97
-
-
84871953641
-
MicroRNAs regulate tumour angiogenesis modulated by endothelial progenitor cells
-
Plummer P.N., Freeman R., Taft R.J., Vider J., Sax M., Umer B.A., Gao D., Johns C., Mattick J.S., Wilton S.D., Ferro V., McMillan N.A., Swarbrick A., Mittal V., Mellick A.S. MicroRNAs regulate tumour angiogenesis modulated by endothelial progenitor cells. Cancer Res. 2013, 73:341-352.
-
(2013)
Cancer Res.
, vol.73
, pp. 341-352
-
-
Plummer, P.N.1
Freeman, R.2
Taft, R.J.3
Vider, J.4
Sax, M.5
Umer, B.A.6
Gao, D.7
Johns, C.8
Mattick, J.S.9
Wilton, S.D.10
Ferro, V.11
McMillan, N.A.12
Swarbrick, A.13
Mittal, V.14
Mellick, A.S.15
-
98
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: an update
-
Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat. Rev. Cancer 2012, 12:159-169.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 159-169
-
-
Pollak, M.1
-
99
-
-
67651149479
-
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
-
Pothof J., Verkaik N.S., van Ijcken W., Wiemer E.A., Ta V.T., van der Horst G.T., Jaspers N.G., van Gent D.C., Hoeijmakers J.H., Persengiev S.P. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J. 2009, 28:2090-2099.
-
(2009)
EMBO J.
, vol.28
, pp. 2090-2099
-
-
Pothof, J.1
Verkaik, N.S.2
van Ijcken, W.3
Wiemer, E.A.4
Ta, V.T.5
van der Horst, G.T.6
Jaspers, N.G.7
van Gent, D.C.8
Hoeijmakers, J.H.9
Persengiev, S.P.10
-
100
-
-
67651210932
-
BMPRII is a direct target of miR-21
-
Qin W., Zhao B., Shi Y., Yao C., Jin L., Jin Y. BMPRII is a direct target of miR-21. Acta Biochim. Biophys. Sin. 2009, 41:618-623.
-
(2009)
Acta Biochim. Biophys. Sin.
, vol.41
, pp. 618-623
-
-
Qin, W.1
Zhao, B.2
Shi, Y.3
Yao, C.4
Jin, L.5
Jin, Y.6
-
101
-
-
84865489973
-
Insulin-like growth factor axis and risk of type 2 diabetes in women
-
Rajpathak S.N., He M., Sun Q., Kaplan R.C., Muzumdar R., Rohan T.E., Gunter M.J., Pollak M., Kim M., Pessin J.E., Beasley J., Wylie-Rosett J., Hu F.B., Strickler H.D. Insulin-like growth factor axis and risk of type 2 diabetes in women. Diabetes 2012, 61:2248-2254.
-
(2012)
Diabetes
, vol.61
, pp. 2248-2254
-
-
Rajpathak, S.N.1
He, M.2
Sun, Q.3
Kaplan, R.C.4
Muzumdar, R.5
Rohan, T.E.6
Gunter, M.J.7
Pollak, M.8
Kim, M.9
Pessin, J.E.10
Beasley, J.11
Wylie-Rosett, J.12
Hu, F.B.13
Strickler, H.D.14
-
102
-
-
84881235291
-
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond
-
Rohwer N., Zasada C., Kempa S., Cramer T. The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond. Oncogene 2012, 32:3569-3576.
-
(2012)
Oncogene
, vol.32
, pp. 3569-3576
-
-
Rohwer, N.1
Zasada, C.2
Kempa, S.3
Cramer, T.4
-
103
-
-
84858776574
-
MicroRNAs in metabolism and metabolic disorders
-
Rottiers V., Näär A.M. MicroRNAs in metabolism and metabolic disorders. Nat. Rev. Mol. Cell Biol. 2012, 13:239-250.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 239-250
-
-
Rottiers, V.1
Näär, A.M.2
-
104
-
-
79953048345
-
The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes
-
Ryu H.S., Park S.Y., Ma D., Zhang J., Lee W. The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes. PLoS One 2011, 6:e17343.
-
(2011)
PLoS One
, vol.6
, pp. e17343
-
-
Ryu, H.S.1
Park, S.Y.2
Ma, D.3
Zhang, J.4
Lee, W.5
-
105
-
-
58549108465
-
Epigenetic therapy upregulates the tumour suppressor microRNA-126 and its host gene EGFL7 in human cancer cells
-
Saito Y., Friedman J.M., Chihara Y., Egger G., Chuang J.C., Liang G. Epigenetic therapy upregulates the tumour suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. Biochem. Biophys. Res. Commun. 2009, 379:726-731.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.379
, pp. 726-731
-
-
Saito, Y.1
Friedman, J.M.2
Chihara, Y.3
Egger, G.4
Chuang, J.C.5
Liang, G.6
-
106
-
-
0036470213
-
Insulin signaling pathways in time and space
-
Saltiel A.R., Pessin J.E. Insulin signaling pathways in time and space. Trends Cell Biol. 2002, 12:65-71.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 65-71
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
107
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson V.B., Rong N.H., Han J., Yang Q., Aris V., Soteropoulos P., Petrelli N.J., Dunn S.P., Krueger L.J. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res. 2007, 67:9762-9770.
-
(2007)
Cancer Res.
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
Yang, Q.4
Aris, V.5
Soteropoulos, P.6
Petrelli, N.J.7
Dunn, S.P.8
Krueger, L.J.9
-
108
-
-
79953654189
-
Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma
-
Santarelli L., Strafella E., Staffolani S., Amati M., Emanuelli M., Sartini D., Pozzi V., Carbonari D., Bracci M., Pignotti E., Mazzanti P., Sabbatini A., Ranaldi R., Gasparini S., Neuzil J., Tomasetti M. Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma. PLoS One 2011, 6:e18232.
-
(2011)
PLoS One
, vol.6
, pp. e18232
-
-
Santarelli, L.1
Strafella, E.2
Staffolani, S.3
Amati, M.4
Emanuelli, M.5
Sartini, D.6
Pozzi, V.7
Carbonari, D.8
Bracci, M.9
Pignotti, E.10
Mazzanti, P.11
Sabbatini, A.12
Ranaldi, R.13
Gasparini, S.14
Neuzil, J.15
Tomasetti, M.16
-
109
-
-
84864881089
-
Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer
-
Sasahira T., Kurihara M., Bhawal U.K., Ueda N., Shimomoto T., Yamamoto K., Kirita T., Kuniyasu H. Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. Br. J. Cancer 2012, 107:700-706.
-
(2012)
Br. J. Cancer
, vol.107
, pp. 700-706
-
-
Sasahira, T.1
Kurihara, M.2
Bhawal, U.K.3
Ueda, N.4
Shimomoto, T.5
Yamamoto, K.6
Kirita, T.7
Kuniyasu, H.8
-
110
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
-
Selak M.A., Armour S.M., MacKenzie E.D., Boulahbel H., Watson D.G., Mansfield K.D., Pan Y., Simon M.C., Thompson C.B., Gottlieb E. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase. Cancer Cell 2005, 7:77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
111
-
-
34347227058
-
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
-
Semenza G.L. Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem. J. 2007, 405:1-9.
-
(2007)
Biochem. J.
, vol.405
, pp. 1-9
-
-
Semenza, G.L.1
-
112
-
-
80051625243
-
Oxygen sensing, homeostasis, and disease
-
Semenza G.L. Oxygen sensing, homeostasis, and disease. N. Engl. J. Med. 2011, 365:537-547.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 537-547
-
-
Semenza, G.L.1
-
113
-
-
84902533403
-
MicroRNAs as therapeutic targets in human cancers
-
Shah M.Y., Calin G.A. MicroRNAs as therapeutic targets in human cancers. Wiley Interdiscip. Rev. 2014, 5(4):537-548.
-
(2014)
Wiley Interdiscip. Rev.
, vol.5
, Issue.4
, pp. 537-548
-
-
Shah, M.Y.1
Calin, G.A.2
-
114
-
-
84894387582
-
Hypoxia-inducible factors link iron homeostasis and erythropoiesis
-
Shah Y.M., Xie L. Hypoxia-inducible factors link iron homeostasis and erythropoiesis. Gastroenterology 2014, 146:630-642.
-
(2014)
Gastroenterology
, vol.146
, pp. 630-642
-
-
Shah, Y.M.1
Xie, L.2
-
115
-
-
33745170043
-
Hepatocellular carcinoma in Txnip-deficient mice
-
Sheth S.S., Bodnar J.S., Ghazalpour A., Thipphavong C.K., Tsutsumi S., Tward A.D., Demant P., Kodama T., Aburatani H., Lusis A.J. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene 2006, 25:3528-3536.
-
(2006)
Oncogene
, vol.25
, pp. 3528-3536
-
-
Sheth, S.S.1
Bodnar, J.S.2
Ghazalpour, A.3
Thipphavong, C.K.4
Tsutsumi, S.5
Tward, A.D.6
Demant, P.7
Kodama, T.8
Aburatani, H.9
Lusis, A.J.10
-
116
-
-
36348994146
-
MicroRNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells
-
Shi B., Sepp-Lorenzino L., Prisco M., Linsley P., de Angelis T., Baserga R. MicroRNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J. Biol. Chem. 2007, 282:32582-32590.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32582-32590
-
-
Shi, B.1
Sepp-Lorenzino, L.2
Prisco, M.3
Linsley, P.4
de Angelis, T.5
Baserga, R.6
-
117
-
-
84865107292
-
MicroRNA-214 downregulation contributes to tumour angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma
-
Shih T.C., Tien Y.J., Wen C.J., Yeh T.S., Yu M.C., Huang C.H., Lee Y.S., Yen T.C., Hsieh S.Y. MicroRNA-214 downregulation contributes to tumour angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. J. Hepatol. 2012, 57:584-591.
-
(2012)
J. Hepatol.
, vol.57
, pp. 584-591
-
-
Shih, T.C.1
Tien, Y.J.2
Wen, C.J.3
Yeh, T.S.4
Yu, M.C.5
Huang, C.H.6
Lee, Y.S.7
Yen, T.C.8
Hsieh, S.Y.9
-
118
-
-
84855466734
-
Regulation of aerobic glycolysis by microRNAs in cancer
-
Singh P.K., Mehla K., Hollingsworth M.A., Johnson K.R. Regulation of aerobic glycolysis by microRNAs in cancer. Mol. Cell. Pharmacol. 2011, 3:125-134.
-
(2011)
Mol. Cell. Pharmacol.
, vol.3
, pp. 125-134
-
-
Singh, P.K.1
Mehla, K.2
Hollingsworth, M.A.3
Johnson, K.R.4
-
119
-
-
84886443752
-
MicroRNAs in the tumour microenvironment: big role for small players
-
Soon P., Kiaris H. MicroRNAs in the tumour microenvironment: big role for small players. Endocr. Relat. Cancer 2013, 20:R257-R267.
-
(2013)
Endocr. Relat. Cancer
, vol.20
, pp. R257-R267
-
-
Soon, P.1
Kiaris, H.2
-
120
-
-
84870886414
-
Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
-
Sotgia F., Whitaker-Menezes D., Martinez-Outschoorn U.E., Salem A.F., Tsirigos A., Lamb R., Sneddon S., Hulit J., Howell A., Lisanti M.P. Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. Cell Cycle 2012, 11:4390-4401.
-
(2012)
Cell Cycle
, vol.11
, pp. 4390-4401
-
-
Sotgia, F.1
Whitaker-Menezes, D.2
Martinez-Outschoorn, U.E.3
Salem, A.F.4
Tsirigos, A.5
Lamb, R.6
Sneddon, S.7
Hulit, J.8
Howell, A.9
Lisanti, M.P.10
-
121
-
-
84899073542
-
MicroRNA-126 modulates the tumour microenvironment by targeting calmodulin-regulated spectrin-associated protein 1 (Camsap1)
-
Sun X., Wang Z.M., Song Y., Tai X.H., Ji W.Y., Gu H. MicroRNA-126 modulates the tumour microenvironment by targeting calmodulin-regulated spectrin-associated protein 1 (Camsap1). Int. J. Oncol. 2014, 44:1678-1684.
-
(2014)
Int. J. Oncol.
, vol.44
, pp. 1678-1684
-
-
Sun, X.1
Wang, Z.M.2
Song, Y.3
Tai, X.H.4
Ji, W.Y.5
Gu, H.6
-
122
-
-
48649102010
-
Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
-
Taguchi A., Yanagisawa K., Tanaka M., Cao K., Matsuyama Y., Goto H., Takahashi T. Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster. Cancer Res. 2008, 68:5540-5545.
-
(2008)
Cancer Res.
, vol.68
, pp. 5540-5545
-
-
Taguchi, A.1
Yanagisawa, K.2
Tanaka, M.3
Cao, K.4
Matsuyama, Y.5
Goto, H.6
Takahashi, T.7
-
123
-
-
84868282332
-
Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems
-
Tang H., Lee M., Sharpe O., Salamone L., Noonan E.J., Hoang C.D., Levine S., Robinson W.H., Shrager J.B. Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB J. 2012, 26:4710-4721.
-
(2012)
FASEB J.
, vol.26
, pp. 4710-4721
-
-
Tang, H.1
Lee, M.2
Sharpe, O.3
Salamone, L.4
Noonan, E.J.5
Hoang, C.D.6
Levine, S.7
Robinson, W.H.8
Shrager, J.B.9
-
125
-
-
84860142623
-
Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients
-
Tomasetti M., Staffolani S., Nocchi L., Neuzil J., Strafella E., Manzella N., Mariotti L., Bracci M., Valentino M., Amati M., Santarelli L. Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients. Clin. Biochem. 2012, 45:575-581.
-
(2012)
Clin. Biochem.
, vol.45
, pp. 575-581
-
-
Tomasetti, M.1
Staffolani, S.2
Nocchi, L.3
Neuzil, J.4
Strafella, E.5
Manzella, N.6
Mariotti, L.7
Bracci, M.8
Valentino, M.9
Amati, M.10
Santarelli, L.11
-
126
-
-
84895544208
-
MicroRNAs as regulators of mitochondrial function: role in cancer suppression
-
Tomasetti M., Neuzil J., Dong L. MicroRNAs as regulators of mitochondrial function: role in cancer suppression. Biochim. Biophys. Acta 2014, 1840:1441-1453.
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 1441-1453
-
-
Tomasetti, M.1
Neuzil, J.2
Dong, L.3
-
127
-
-
84928880532
-
MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with mitochondrial function
-
Tomasetti M., Nocchi L., Staffolani S., Manzella N., Amati M., Goodwin J., Nguyen M., Kluckova K., Bajzikova M., Sobol M., Hozak P., Lettlova S., Truksa J., Lee W., Dong L., Santarelli L., Neuzil J. MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with mitochondrial function. Antioxid. Redox Signal. 2014, (in press).
-
(2014)
Antioxid. Redox Signal.
-
-
Tomasetti, M.1
Nocchi, L.2
Staffolani, S.3
Manzella, N.4
Amati, M.5
Goodwin, J.6
Nguyen, M.7
Kluckova, K.8
Bajzikova, M.9
Sobol, M.10
Hozak, P.11
Lettlova, S.12
Truksa, J.13
Lee, W.14
Dong, L.15
Santarelli, L.16
Neuzil, J.17
-
128
-
-
34547660196
-
FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system
-
Tothova Z., Gilliland D.G. FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system. Cell Stem Cell 2007, 1:140-152.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 140-152
-
-
Tothova, Z.1
Gilliland, D.G.2
-
129
-
-
79957900919
-
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
-
Trang P., Wiggins J.F., Daige C.L., Cho C., Omotola M., Brown D., Weidhaas J.B., Bader A.G., Slack F.J. Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol. Ther. 2011, 19:1116-1122.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1116-1122
-
-
Trang, P.1
Wiggins, J.F.2
Daige, C.L.3
Cho, C.4
Omotola, M.5
Brown, D.6
Weidhaas, J.B.7
Bader, A.G.8
Slack, F.J.9
-
130
-
-
79551509783
-
Hippo/Mst1 stimulates transcription of NOXA in a FoxO1-dependent manner
-
Valis K., Prochazka L., Boura E., Chladova M., Obsil T., Rohlena J., Truksa J., Dong L.F., Ralph S.J., Neuzil J. Hippo/Mst1 stimulates transcription of NOXA in a FoxO1-dependent manner. Cancer Res. 2011, 71:946-954.
-
(2011)
Cancer Res.
, vol.71
, pp. 946-954
-
-
Valis, K.1
Prochazka, L.2
Boura, E.3
Chladova, M.4
Obsil, T.5
Rohlena, J.6
Truksa, J.7
Dong, L.F.8
Ralph, S.J.9
Neuzil, J.10
-
131
-
-
80052242132
-
Targeting cancer metabolism: a therapeutic window opens
-
Vander Heiden M.G. Targeting cancer metabolism: a therapeutic window opens. Nat. Rev. Drug Discov. 2011, 10:671-684.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 671-684
-
-
Vander Heiden, M.G.1
-
132
-
-
48549106378
-
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis
-
Wang S., Aurora A.B., Johnson B.A., Qi X., McAnally J., Hill J.A., Richardson J.A., Bassel-Duby R., Olson E.N. The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev. Cell 2008, 15:261-271.
-
(2008)
Dev. Cell
, vol.15
, pp. 261-271
-
-
Wang, S.1
Aurora, A.B.2
Johnson, B.A.3
Qi, X.4
McAnally, J.5
Hill, J.A.6
Richardson, J.A.7
Bassel-Duby, R.8
Olson, E.N.9
-
133
-
-
84899490560
-
MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling
-
Wang Y., Hu C., Cheng J., Chen B., Ke Q., Lv Z., Wu J., Zhou Y. MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. Biochem. Biophys. Res. Commun. 2014, 446(4):1255-1260.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.446
, Issue.4
, pp. 1255-1260
-
-
Wang, Y.1
Hu, C.2
Cheng, J.3
Chen, B.4
Ke, Q.5
Lv, Z.6
Wu, J.7
Zhou, Y.8
-
134
-
-
84858604270
-
Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate
-
Ward P.S., Thompson C.B. Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate. Cancer Cell 2012, 21:297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
135
-
-
79952167247
-
Hypoxia. 2. Hypoxia regulates cellular metabolism
-
Wheaton W.W., Chandel N.S. Hypoxia. 2. Hypoxia regulates cellular metabolism. Am. J. Physiol. 2011, 300:C385-C393.
-
(2011)
Am. J. Physiol.
, vol.300
, pp. C385-C393
-
-
Wheaton, W.W.1
Chandel, N.S.2
-
136
-
-
84896737116
-
The role of the tumour-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets
-
Wood S.L., Pernemalm M., Crosbie P.A., Whetton A.D. The role of the tumour-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets. Cancer Treat. Rev. 2014, 40:558-566.
-
(2014)
Cancer Treat. Rev.
, vol.40
, pp. 558-566
-
-
Wood, S.L.1
Pernemalm, M.2
Crosbie, P.A.3
Whetton, A.D.4
-
137
-
-
77950905821
-
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
-
Yamakuchi M., Lotterman C.D., Bao C., Hruban R.H., Karim B., Mendell J.T., Huso D., Lowenstein C.J. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:6334-6339.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 6334-6339
-
-
Yamakuchi, M.1
Lotterman, C.D.2
Bao, C.3
Hruban, R.H.4
Karim, B.5
Mendell, J.T.6
Huso, D.7
Lowenstein, C.J.8
-
138
-
-
79956359793
-
MicroRNA-22 regulates hypoxia signaling in colon cancer cells
-
Yamakuchi M., Yagi S., Ito T., Lowenstein C.J. MicroRNA-22 regulates hypoxia signaling in colon cancer cells. PLoS One 2011, 6:e20291.
-
(2011)
PLoS One
, vol.6
, pp. e20291
-
-
Yamakuchi, M.1
Yagi, S.2
Ito, T.3
Lowenstein, C.J.4
-
139
-
-
33644819964
-
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
-
Yanaihara N., Caplen N., Bowman E., Seike M., Kumamoto K., Yi M., Stephens R.M., Okamoto A., Yokota J., Tanaka T., Calin G.A., Liu C.G., Croce C.M., Harris C.C. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006, 9:189-198.
-
(2006)
Cancer Cell
, vol.9
, pp. 189-198
-
-
Yanaihara, N.1
Caplen, N.2
Bowman, E.3
Seike, M.4
Kumamoto, K.5
Yi, M.6
Stephens, R.M.7
Okamoto, A.8
Yokota, J.9
Tanaka, T.10
Calin, G.A.11
Liu, C.G.12
Croce, C.M.13
Harris, C.C.14
-
140
-
-
77955967332
-
Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L)
-
Yang D., Wang M.T., Tang Y., Chen Y., Jiang H., Jones T.T., Rao K., Brewer G.J., Singh K.K., Nie D. Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). Cancer Biol. Ther. 2010, 9:122-133.
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 122-133
-
-
Yang, D.1
Wang, M.T.2
Tang, Y.3
Chen, Y.4
Jiang, H.5
Jones, T.T.6
Rao, K.7
Brewer, G.J.8
Singh, K.K.9
Nie, D.10
-
141
-
-
84875158140
-
HIFs, angiogenesis, and cancer
-
Yang Y., Sun M., Wang L., Jiao B. HIFs, angiogenesis, and cancer. J. Cell. Biochem. 2013, 114:967-974.
-
(2013)
J. Cell. Biochem.
, vol.114
, pp. 967-974
-
-
Yang, Y.1
Sun, M.2
Wang, L.3
Jiao, B.4
-
142
-
-
84890498926
-
Hypoxia-induced deregulation of miR-126 and its regulative effect on VEGF and MMP-9 expression
-
Ye P., Liu J., He F., Xu W., Yao K. Hypoxia-induced deregulation of miR-126 and its regulative effect on VEGF and MMP-9 expression. Int. J. Med. Sci. 2013, 11:17-23.
-
(2013)
Int. J. Med. Sci.
, vol.11
, pp. 17-23
-
-
Ye, P.1
Liu, J.2
He, F.3
Xu, W.4
Yao, K.5
-
143
-
-
84878830070
-
MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α
-
Yeh Y.M., Chuang C.M., Chao K.C., Wang L.H. MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α. Int. J. Cancer 2013, 133(4):867-878.
-
(2013)
Int. J. Cancer
, vol.133
, Issue.4
, pp. 867-878
-
-
Yeh, Y.M.1
Chuang, C.M.2
Chao, K.C.3
Wang, L.H.4
-
144
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang H., Gao P., Fukuda R., Kumar G., Krishnamachary B., Zeller K.I., Dang C.V., Semenza G.L. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 2007, 11:407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
Dang, C.V.7
Semenza, G.L.8
-
145
-
-
54449099588
-
The cell growth suppressor, mir-126, targets IRS-1
-
Zhang J., Du Y.Y., Lin Y.F., Chen Y.T., Yang L., Wang H.J., Ma D. The cell growth suppressor, mir-126, targets IRS-1. Biochem. Biophys. Res. Commun. 2008, 377:136-140.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 136-140
-
-
Zhang, J.1
Du, Y.Y.2
Lin, Y.F.3
Chen, Y.T.4
Yang, L.5
Wang, H.J.6
Ma, D.7
-
146
-
-
80052962211
-
Akt, FoxO and regulation of apoptosis
-
Zhang X., Tang N., Hadden T.J., Rishi A.K. Akt, FoxO and regulation of apoptosis. Biochim. Biophys. Acta 2011, 1813:1978-1986.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1978-1986
-
-
Zhang, X.1
Tang, N.2
Hadden, T.J.3
Rishi, A.K.4
-
147
-
-
84882686726
-
Epigenetic silencing of miR-126 contributes to tumour invasion and angiogenesis in colorectal cancer
-
Zhang Y., Wang X., Xu B., Wang B., Wang Z., Liang Y., Zhou J., Hu J., Jiang B. Epigenetic silencing of miR-126 contributes to tumour invasion and angiogenesis in colorectal cancer. Oncol. Rep. 2013, 30:1976-1984.
-
(2013)
Oncol. Rep.
, vol.30
, pp. 1976-1984
-
-
Zhang, Y.1
Wang, X.2
Xu, B.3
Wang, B.4
Wang, Z.5
Liang, Y.6
Zhou, J.7
Hu, J.8
Jiang, B.9
-
148
-
-
84874629992
-
MiR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis
-
Zhang Y., Yang P., Sun T., Li D., Xu X., Rui Y., Li C., Chong M., Ibrahim T., Mercatali L., Amadori D., Lu X., Xie D., Li Q.J., Wang X.F. miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat. Cell Biol. 2013, 15:284-294.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 284-294
-
-
Zhang, Y.1
Yang, P.2
Sun, T.3
Li, D.4
Xu, X.5
Rui, Y.6
Li, C.7
Chong, M.8
Ibrahim, T.9
Mercatali, L.10
Amadori, D.11
Lu, X.12
Xie, D.13
Li, Q.J.14
Wang, X.F.15
-
149
-
-
79959861423
-
Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism
-
Zhao Y., Liu H., Liu Z., Ding Y., Ledoux S.P., Wilson G.L., Voellmy R., Lin Y., Lin W., Nahta R., Liu B., Fodstad O., Chen J., Wu Y., Price J.E., Tan M. Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism. Cancer Res. 2011, 71:4585-4597.
-
(2011)
Cancer Res.
, vol.71
, pp. 4585-4597
-
-
Zhao, Y.1
Liu, H.2
Liu, Z.3
Ding, Y.4
Ledoux, S.P.5
Wilson, G.L.6
Voellmy, R.7
Lin, Y.8
Lin, W.9
Nahta, R.10
Liu, B.11
Fodstad, O.12
Chen, J.13
Wu, Y.14
Price, J.E.15
Tan, M.16
-
150
-
-
84875890762
-
Targeting cellular metabolism to improve cancer therapeutics
-
Zhao Y., Butler E.B., Tan M. Targeting cellular metabolism to improve cancer therapeutics. Cell Death Dis. 2013, 4:e532.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e532
-
-
Zhao, Y.1
Butler, E.B.2
Tan, M.3
-
151
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1 alpha in common human cancers and their metastases
-
Zhong H., De Marzo A.M., Laughner E., Lim M., Hilton D.A., Zagzag D., Buechler P., Isaacs W.B., Semenza G.L., Simons J.W. Overexpression of hypoxia-inducible factor 1 alpha in common human cancers and their metastases. Cancer Res. 1999, 59:5830-5835.
-
(1999)
Cancer Res.
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
152
-
-
84900539635
-
Multipoint targeting of the PI3K/mTOR pathway in mesothelioma
-
Zhou S., Liu L., Li H., Eilers G., Kuang Y., Shi S., Yan Z., Li X., Corson J.M., Meng F., Zhou H., Sheng Q., Fletcher J.A., Ou W.B. Multipoint targeting of the PI3K/mTOR pathway in mesothelioma. Br. J. Cancer. 2014, 110(10):2479-2488.
-
(2014)
Br. J. Cancer.
, vol.110
, Issue.10
, pp. 2479-2488
-
-
Zhou, S.1
Liu, L.2
Li, H.3
Eilers, G.4
Kuang, Y.5
Shi, S.6
Yan, Z.7
Li, X.8
Corson, J.M.9
Meng, F.10
Zhou, H.11
Sheng, Q.12
Fletcher, J.A.13
Ou, W.B.14
-
153
-
-
79953702227
-
Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2
-
Zhu N., Zhang D., Xie H., Zhou Z., Chen H., Hu T., Bai Y., Shen Y., Yuan W., Jing Q., Qin Y. Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. Mol. Cell. Biochem. 2011, 351:157-164.
-
(2011)
Mol. Cell. Biochem.
, vol.351
, pp. 157-164
-
-
Zhu, N.1
Zhang, D.2
Xie, H.3
Zhou, Z.4
Chen, H.5
Hu, T.6
Bai, Y.7
Shen, Y.8
Yuan, W.9
Jing, Q.10
Qin, Y.11
-
154
-
-
84866093563
-
Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
-
Zhuang G., Wu X., Jiang Z., Kasman I., Yao J., Guan Y., Oeh J., Modrusan Z., Bais C., Sampath D., Ferrara N. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J. 2012, 31:3513-3523.
-
(2012)
EMBO J.
, vol.31
, pp. 3513-3523
-
-
Zhuang, G.1
Wu, X.2
Jiang, Z.3
Kasman, I.4
Yao, J.5
Guan, Y.6
Oeh, J.7
Modrusan, Z.8
Bais, C.9
Sampath, D.10
Ferrara, N.11
|