메뉴 건너뛰기




Volumn 63, Issue 2, 2011, Pages 94-100

MiR-210: More than a silent player in hypoxia

Author keywords

apoptosis; cancer; hypoxia; ischemia; metabolism; microRNA; miR 210; mitochondria

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; MICRORNA; MICRORNA 210; UNCLASSIFIED DRUG;

EID: 79952137486     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.427     Document Type: Review
Times cited : (244)

References (61)
  • 1
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • Semenza, G. L., (2010) Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 29, 625-634.
    • (2010) Oncogene , vol.29 , pp. 625-634
    • Semenza, G.L.1
  • 2
    • 77950901310 scopus 로고    scopus 로고
    • Vascular responses to hypoxia and ischemia
    • Semenza, G. L., (2010) Vascular responses to hypoxia and ischemia. Arterioscler. Thromb. Vasc. Biol. 30, 648-652.
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 648-652
    • Semenza, G.L.1
  • 5
    • 54949154476 scopus 로고    scopus 로고
    • MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
    • Hua, Z., Lv, Q., Ye, W., Wong, C. K., and, Cai, G., (2006) MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One 1, e116.
    • (2006) PLoS One , vol.1
    • Hua, Z.1    Lv, Q.2    Ye, W.3    Wong, C.K.4    Cai, G.5
  • 6
    • 34147116217 scopus 로고    scopus 로고
    • The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts
    • DOI 10.1093/molehr/gam006
    • Donker, R. B., Mouillet, J. F., Nelson, D. M., and, Sadovsky, Y., (2007) The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts. Mol. Hum. Reprod. 13, 273-279. (Pubitemid 46554745)
    • (2007) Molecular Human Reproduction , vol.13 , Issue.4 , pp. 273-279
    • Donker, R.B.1    Mouillet, J.-F.2    Nelson, D.M.3    Sadovsky, Y.4
  • 7
    • 64649083602 scopus 로고    scopus 로고
    • Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
    • Guimbellot, J. S., Erickson, S. W., Mehta, T., Wen, H., and, Page, G. P., (2009) Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis. BMC Med. Genomics 2, 15.
    • (2009) BMC Med. Genomics , vol.2 , pp. 15
    • Guimbellot, J.S.1    Erickson, S.W.2    Mehta, T.3    Wen, H.4    Page, G.P.5
  • 10
    • 47049119934 scopus 로고    scopus 로고
    • MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3
    • Fasanaro, P., D'Alessandra, Y., Di Stefano, V., Melchionna, R., and, Romani, S., (2008) MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J. Biol. Chem. 283, 15878-15883.
    • (2008) J. Biol. Chem. , vol.283 , pp. 15878-15883
    • Fasanaro, P.1    D'Alessandra, Y.2    Di Stefano, V.3    Melchionna, R.4    Romani, S.5
  • 11
    • 45549086958 scopus 로고    scopus 로고
    • Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210
    • Pulkkinen, K., Malm, T., Turunen, M., Koistinaho, J., and, Yla-Herttuala, S., (2008) Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210. FEBS Lett. 582, 2397-2401.
    • (2008) FEBS Lett. , vol.582 , pp. 2397-2401
    • Pulkkinen, K.1    Malm, T.2    Turunen, M.3    Koistinaho, J.4    Yla-Herttuala, S.5
  • 12
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D. P., (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 13
    • 34547938506 scopus 로고    scopus 로고
    • MicroRNAs: A Safeguard against Turmoil?
    • DOI 10.1016/j.cell.2007.08.010, PII S009286740701032X
    • Leung, A. K., and, Sharp, P. A., (2007) microRNAs: a safeguard against turmoil? Cell 130, 581-585. (Pubitemid 47268068)
    • (2007) Cell , vol.130 , Issue.4 , pp. 581-585
    • Leung, A.K.L.1    Sharp, P.A.2
  • 14
    • 33748928159 scopus 로고    scopus 로고
    • The Diverse Functions of MicroRNAs in Animal Development and Disease
    • DOI 10.1016/j.devcel.2006.09.009, PII S1534580706004023
    • Kloosterman, W. P., and, Plasterk, R. H., (2006) The diverse functions of microRNAs in animal development and disease. Dev. Cell 11, 441-450. (Pubitemid 44430905)
    • (2006) Developmental Cell , vol.11 , Issue.4 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.A.2
  • 16
    • 59149091637 scopus 로고    scopus 로고
    • MicroRNA regulation of DNA repair gene expression in hypoxic stress
    • Crosby, M. E., Kulshreshtha, R., Ivan, M., and, Glazer, P. M., (2009) MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 69, 1221-1229.
    • (2009) Cancer Res. , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 19
    • 0033776536 scopus 로고    scopus 로고
    • Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
    • Ohh, M., Park, C. W., Ivan, M., Hoffman, M. A., and, Kim, T. Y., (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat. Cell Biol. 2, 423-427.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 423-427
    • Ohh, M.1    Park, C.W.2    Ivan, M.3    Hoffman, M.A.4    Kim, T.Y.5
  • 20
    • 51349103144 scopus 로고    scopus 로고
    • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
    • Foekens, J. A., Sieuwerts, A. M., Smid, M., Look, M. P., and, de Weerd, V., (2008) Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc. Natl. Acad. Sci. USA 105, 13021-13026.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 13021-13026
    • Foekens, J.A.1    Sieuwerts, A.M.2    Smid, M.3    Look, M.P.4    De Weerd, V.5
  • 21
    • 77951463320 scopus 로고    scopus 로고
    • Hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer
    • Gee, H. E., Camps, C., Buffa, F. M., Patiar, S., and, Winter, S. C., (2010) hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer 116, 2148-2158.
    • (2010) Cancer , vol.116 , pp. 2148-2158
    • Gee, H.E.1    Camps, C.2    Buffa, F.M.3    Patiar, S.4    Winter, S.C.5
  • 25
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
    • DOI 10.1016/j.ccr.2007.04.001, PII S1535610807001158
    • Zhang, H., Gao, P., Fukuda, R., Kumar, G., and, Krishnamachary, B., (2007) HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11, 407-420. (Pubitemid 46670080)
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, ChiV.7    Semenza, G.L.8
  • 26
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • Chan, S. Y., Zhang, Y. Y., Hemann, C., Mahoney, C. E., Zweier, J. L., and, Loscalzo, J., (2009) MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 10, 273-284.
    • (2009) Cell Metab. , vol.10 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 27
    • 71749100911 scopus 로고    scopus 로고
    • An integrated approach for experimental target identification of hypoxia-induced miR-210
    • Fasanaro, P., Greco, S., Lorenzi, M., Pescatori, M., and, Brioschi, M., (2009) An integrated approach for experimental target identification of hypoxia-induced miR-210. J. Biol. Chem. 284, 35134-35143.
    • (2009) J. Biol. Chem. , vol.284 , pp. 35134-35143
    • Fasanaro, P.1    Greco, S.2    Lorenzi, M.3    Pescatori, M.4    Brioschi, M.5
  • 28
    • 77956402239 scopus 로고    scopus 로고
    • MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
    • Favaro, E., Ramachandran, A., McCormick, R., Gee, H., and, Blancher, C., (2010) MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One 5, e10345.
    • (2010) PLoS One , vol.5
    • Favaro, E.1    Ramachandran, A.2    McCormick, R.3    Gee, H.4    Blancher, C.5
  • 29
    • 77955170881 scopus 로고    scopus 로고
    • Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
    • Chen, Z., Li, Y., Zhang, H., Huang, P., and, Luthra, R., (2010) Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 29, 4362-4368.
    • (2010) Oncogene , vol.29 , pp. 4362-4368
    • Chen, Z.1    Li, Y.2    Zhang, H.3    Huang, P.4    Luthra, R.5
  • 30
    • 33644623262 scopus 로고    scopus 로고
    • Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis
    • Tong, W. H., and, Rouault, T. A., (2006) Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. Cell Metab. 3, 199-210.
    • (2006) Cell Metab. , vol.3 , pp. 199-210
    • Tong, W.H.1    Rouault, T.A.2
  • 31
    • 84922104094 scopus 로고    scopus 로고
    • MiR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity
    • Oct 1. [Epub ahead of print] PMID 20885442
    • Puissegur, M. P., Mazure, N. M., Bertero, T., Pradelli, L., and, Grosso, S., (2010) miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity. Cell Death Differ., Oct 1. [Epub ahead of print] PMID 20885442.
    • (2010) Cell Death Differ.
    • Puissegur, M.P.1    Mazure, N.M.2    Bertero, T.3    Pradelli, L.4    Grosso, S.5
  • 32
    • 77958501429 scopus 로고    scopus 로고
    • Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel
    • Liu, M., Liu, H., and, Dudley, S. C. Jr., (2010) Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel. Circ. Res. 107, 967-974.
    • (2010) Circ. Res. , vol.107 , pp. 967-974
    • Liu, M.1    Liu, H.2    Dudley, Jr.S.C.3
  • 33
    • 0032556865 scopus 로고    scopus 로고
    • Synergistic actions of Rad51 and Rad52 in recombination and DNA repair
    • DOI 10.1038/34937
    • Benson, F. E., Baumann, P., and, West, S. C., (1998) Synergistic actions of Rad51 and Rad52 in recombination and DNA repair. Nature 391, 401-404. (Pubitemid 28093516)
    • (1998) Nature , vol.391 , Issue.6665 , pp. 401-404
    • Benson, F.E.1    Baumann, P.2    West, S.C.3
  • 34
    • 0029112483 scopus 로고
    • DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA
    • Sung, P., and, Robberson, D. L., (1995) DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. Cell 82, 453-461.
    • (1995) Cell , vol.82 , pp. 453-461
    • Sung, P.1    Robberson, D.L.2
  • 36
    • 70450240736 scopus 로고    scopus 로고
    • Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2
    • Kim, H. W., Haider, H. K., Jiang, S., and, Ashraf, M., (2009) Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. J. Biol. Chem. 284, 33161-33168.
    • (2009) J. Biol. Chem. , vol.284 , pp. 33161-33168
    • Kim, H.W.1    Haider, H.K.2    Jiang, S.3    Ashraf, M.4
  • 37
    • 78650944900 scopus 로고    scopus 로고
    • MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1)
    • Tsuchiya, S., Fujiwara, T., Sato, F., Shimada, Y., and, Tanaka, E., (2011) MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). J. Biol. Chem. 286, 420-428.
    • (2011) J. Biol. Chem. , vol.286 , pp. 420-428
    • Tsuchiya, S.1    Fujiwara, T.2    Sato, F.3    Shimada, Y.4    Tanaka, E.5
  • 38
    • 69749107748 scopus 로고    scopus 로고
    • MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT
    • Zhang, Z., Sun, H., Dai, H., Walsh, R. M., and, Imakura, M., (2009) MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle 8, 2756-2768.
    • (2009) Cell Cycle , vol.8 , pp. 2756-2768
    • Zhang, Z.1    Sun, H.2    Dai, H.3    Walsh, R.M.4    Imakura, M.5
  • 41
    • 41249102422 scopus 로고    scopus 로고
    • MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion
    • DOI 10.1161/STROKEAHA.107.500736
    • Jeyaseelan, K., Lim, K. Y., and, Armugam, A., (2008) MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 39, 959-966. (Pubitemid 351619577)
    • (2008) Stroke , vol.39 , Issue.3 , pp. 959-966
    • Jeyaseelan, K.1    Lim, K.Y.2    Armugam, A.3
  • 42
    • 77951043486 scopus 로고    scopus 로고
    • Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds
    • Biswas, S., Roy, S., Banerjee, J., Hussain, S. R., and, Khanna, S., (2010) Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Proc. Natl. Acad. Sci. USA 107, 6976-6981.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 6976-6981
    • Biswas, S.1    Roy, S.2    Banerjee, J.3    Hussain, S.R.4    Khanna, S.5
  • 43
    • 77249178696 scopus 로고    scopus 로고
    • MicroRNA microarray expression profiling in human myocardial infarction
    • Bostjancic, E., Zidar, N., and, Glavac, D., (2009) MicroRNA microarray expression profiling in human myocardial infarction. Dis. Markers 27, 255-268.
    • (2009) Dis. Markers , vol.27 , pp. 255-268
    • Bostjancic, E.1    Zidar, N.2    Glavac, D.3
  • 44
    • 78650512343 scopus 로고    scopus 로고
    • Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans
    • Li, T., Cao, H., Zhuang, J., Wan, J., and, Guan, M., (2010) Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans. Clin. Chim. Acta 412, 66-70.
    • (2010) Clin. Chim. Acta , vol.412 , pp. 66-70
    • Li, T.1    Cao, H.2    Zhuang, J.3    Wan, J.4    Guan, M.5
  • 45
    • 33847680037 scopus 로고    scopus 로고
    • Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia
    • Pineles, B. L., Romero, R., Montenegro, D., Tarca, A. L., and, Han, Y. M., (2007) Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am. J. Obstet. Gynecol. 196, 261.e1-261.e6.
    • (2007) Am. J. Obstet. Gynecol. , vol.196
    • Pineles, B.L.1    Romero, R.2    Montenegro, D.3    Tarca, A.L.4    Han, Y.M.5
  • 47
    • 67349233035 scopus 로고    scopus 로고
    • Differential expression profile of microRNAs in human placentas from preeclamptic pregnancies vs normal pregnancies
    • Zhu, X. M., Han, T., Sargent, I. L., Yin, G. W., and, Yao, Y. Q., (2009) Differential expression profile of microRNAs in human placentas from preeclamptic pregnancies vs normal pregnancies. Am. J. Obstet. Gynecol. 200, 661.e1-661.e7.
    • (2009) Am. J. Obstet. Gynecol , vol.200
    • Zhu, X.M.1    Han, T.2    Sargent, I.L.3    Yin, G.W.4    Yao, Y.Q.5
  • 49
    • 36048965546 scopus 로고    scopus 로고
    • Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1-like gene (GPD1-L) mutations in sudden infant death syndrome
    • DOI 10.1161/CIRCULATIONAHA.107.704627
    • Van Norstrand, D. W., Valdivia, C. R., Tester, D. J., Ueda, K., and, London, B., (2007) Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. Circulation 116, 2253-2259. (Pubitemid 350100330)
    • (2007) Circulation , vol.116 , Issue.20 , pp. 2253-2259
    • Van Norstrand, D.W.1    Valdivia, C.R.2    Tester, D.J.3    Ueda, K.4    London, B.5    Makielski, J.C.6    Ackerman, M.J.7
  • 50
    • 41149169596 scopus 로고    scopus 로고
    • Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance
    • Mochel, F., Knight, M. A., Tong, W. H., Hernandez, D., and, Ayyad, K., (2008) Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. Am. J. Hum. Genet. 82, 652-660.
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 652-660
    • Mochel, F.1    Knight, M.A.2    Tong, W.H.3    Hernandez, D.4    Ayyad, K.5
  • 51
    • 77952840905 scopus 로고    scopus 로고
    • MicroRNAs-targeting and target prediction
    • Saito, T., and, Saetrom, P., (2010) MicroRNAs-targeting and target prediction. New Biotechnol. 27, 243-249.
    • (2010) New Biotechnol. , vol.27 , pp. 243-249
    • Saito, T.1    Saetrom, P.2
  • 52
    • 67649381623 scopus 로고    scopus 로고
    • MiR-210 promotes osteoblastic differentiation through inhibition of AcvR1b
    • Mizuno, Y., Tokuzawa, Y., Ninomiya, Y., Yagi, K., and, Yatsuka-Kanesaki, Y., (2009) miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b. FEBS Lett. 583, 2263-2268.
    • (2009) FEBS Lett. , vol.583 , pp. 2263-2268
    • Mizuno, Y.1    Tokuzawa, Y.2    Ninomiya, Y.3    Yagi, K.4    Yatsuka-Kanesaki, Y.5
  • 53
    • 77952448162 scopus 로고    scopus 로고
    • A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway
    • Qin, L., Chen, Y., Niu, Y., Chen, W., and, Wang, Q., (2010) A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics 11, 320.
    • (2010) BMC Genomics , vol.11 , pp. 320
    • Qin, L.1    Chen, Y.2    Niu, Y.3    Chen, W.4    Wang, Q.5
  • 54
    • 70349168446 scopus 로고    scopus 로고
    • Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation
    • Huang, X., Ding, L., Bennewith, K. L., Tong, R. T., and, Welford, S. M., (2009) Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Mol. Cell 35, 856-867.
    • (2009) Mol. Cell , vol.35 , pp. 856-867
    • Huang, X.1    Ding, L.2    Bennewith, K.L.3    Tong, R.T.4    Welford, S.M.5
  • 55
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • Lanford, R. E., Hildebrandt-Eriksen, E. S., Petri, A., Persson, R., and, Lindow, M., (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327, 198-201.
    • (2010) Science , vol.327 , pp. 198-201
    • Lanford, R.E.1    Hildebrandt-Eriksen, E.S.2    Petri, A.3    Persson, R.4    Lindow, M.5
  • 56
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • Garzon, R., Marcucci, G., and, Croce, C. M., (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug Discov. 9, 775-789.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 58
    • 70449700281 scopus 로고    scopus 로고
    • MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease
    • Wang, J., Chen, J., Chang, P., LeBlanc, A., and, Li, D., (2009) MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prev. Res. 2, 807-813.
    • (2009) Cancer Prev. Res. , vol.2 , pp. 807-813
    • Wang, J.1    Chen, J.2    Chang, P.3    Leblanc, A.4    Li, D.5
  • 59
    • 77957243894 scopus 로고    scopus 로고
    • MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
    • Hu, S., Huang, M., Li, Z., Jia, F., and, Ghosh, Z., (2010) MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 122, S124-S131.
    • (2010) Circulation , vol.122
    • Hu, S.1    Huang, M.2    Li, Z.3    Jia, F.4    Ghosh, Z.5
  • 60
    • 54049105673 scopus 로고    scopus 로고
    • Hypoxia response and microRNAs: No longer two separate worlds
    • Ivan, M., Harris, A. L., Martelli, F., and, Kulshreshtha, R., (2008) Hypoxia response and microRNAs: no longer two separate worlds. J. Cell Mol. Med. 12, 1426-1431.
    • (2008) J. Cell Mol. Med. , vol.12 , pp. 1426-1431
    • Ivan, M.1    Harris, A.L.2    Martelli, F.3    Kulshreshtha, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.