-
1
-
-
27844445642
-
Perturbations of the AKT signaling pathway in human cancer
-
Altomare D.A., and Testa J.R. Perturbations of the AKT signaling pathway in human cancer. Oncogene 24 (2005) 7455-7464
-
(2005)
Oncogene
, vol.24
, pp. 7455-7464
-
-
Altomare, D.A.1
Testa, J.R.2
-
2
-
-
0035909313
-
Forkhead transcription factors contribute to execution of the mitotic programme in mammals
-
Alvarez B., Martinez A.C., Burgering B.M., and Carrera A.C. Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature 413 (2001) 744-747
-
(2001)
Nature
, vol.413
, pp. 744-747
-
-
Alvarez, B.1
Martinez, A.C.2
Burgering, B.M.3
Carrera, A.C.4
-
3
-
-
0032518255
-
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily
-
Anderson M.J., Viars C.S., Czekay S., Cavenee W.K., and Arden K.C. Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. Genomics 47 (1998) 187-199
-
(1998)
Genomics
, vol.47
, pp. 187-199
-
-
Anderson, M.J.1
Viars, C.S.2
Czekay, S.3
Cavenee, W.K.4
Arden, K.C.5
-
4
-
-
1642580499
-
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1
-
Bakker W.J., Blazquez-Domingo M., Kolbus A., Besooyen J., Steinlein P., Beug H., Coffer P.J., Lowenberg B., von Lindern M., and van Dijk T.B. FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J. Cell Biol. 164 (2004) 175-184
-
(2004)
J. Cell Biol.
, vol.164
, pp. 175-184
-
-
Bakker, W.J.1
Blazquez-Domingo, M.2
Kolbus, A.3
Besooyen, J.4
Steinlein, P.5
Beug, H.6
Coffer, P.J.7
Lowenberg, B.8
von Lindern, M.9
van Dijk, T.B.10
-
6
-
-
33646024345
-
DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest
-
Baugh L.R., and Sternberg P.W. DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest. Curr. Biol. 16 (2006) 780-785
-
(2006)
Curr. Biol.
, vol.16
, pp. 780-785
-
-
Baugh, L.R.1
Sternberg, P.W.2
-
7
-
-
33744976074
-
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
-
Berdichevsky A., Viswanathan M., Horvitz H.R., and Guarente L. C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. Cell 125 (2006) 1165-1177
-
(2006)
Cell
, vol.125
, pp. 1165-1177
-
-
Berdichevsky, A.1
Viswanathan, M.2
Horvitz, H.R.3
Guarente, L.4
-
8
-
-
33644772542
-
Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling
-
Berman J.R., and Kenyon C. Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124 (2006) 1055-1068
-
(2006)
Cell
, vol.124
, pp. 1055-1068
-
-
Berman, J.R.1
Kenyon, C.2
-
9
-
-
34047095297
-
The Two TORCs and Akt
-
Bhaskar P.T., and Hay N. The Two TORCs and Akt. Dev. Cell 12 (2007) 487-502
-
(2007)
Dev. Cell
, vol.12
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
10
-
-
4444290010
-
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
-
Blanpain C., Lowry W.E., Geoghegan A., Polak L., and Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118 (2004) 635-648
-
(2004)
Cell
, vol.118
, pp. 635-648
-
-
Blanpain, C.1
Lowry, W.E.2
Geoghegan, A.3
Polak, L.4
Fuchs, E.5
-
11
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D., and Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3 (1997) 730-737
-
(1997)
Nat. Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
12
-
-
0031031378
-
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
-
Borkhardt A., Repp R., Haas O.A., Leis T., Harbott J., Kreuder J., Hammermann J., Henn T., and Lampert F. Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene 14 (1997) 195-202
-
(1997)
Oncogene
, vol.14
, pp. 195-202
-
-
Borkhardt, A.1
Repp, R.2
Haas, O.A.3
Leis, T.4
Harbott, J.5
Kreuder, J.6
Hammermann, J.7
Henn, T.8
Lampert, F.9
-
13
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., and Greenberg M.E. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857-868
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
14
-
-
0037018148
-
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
-
Brunet A., Kanai F., Stehn J., Xu J., Sarbassova D., Frangioni J.V., Dalal S.N., DeCaprio J.A., Greenberg M.E., and Yaffe M.B. 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J. Cell Biol. 156 (2002) 817-828
-
(2002)
J. Cell Biol.
, vol.156
, pp. 817-828
-
-
Brunet, A.1
Kanai, F.2
Stehn, J.3
Xu, J.4
Sarbassova, D.5
Frangioni, J.V.6
Dalal, S.N.7
DeCaprio, J.A.8
Greenberg, M.E.9
Yaffe, M.B.10
-
15
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303 (2004) 2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
16
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon D.H., Miao L., Kollipara R., Horner J.W., and DePinho R.A. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 301 (2003) 215-218
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
DePinho, R.A.5
-
17
-
-
0033694302
-
Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
-
Cheng T., Rodrigues N., Dombkowski D., Stier S., and Scadden D.T. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat. Med. 6 (2000) 1235-1240
-
(2000)
Nat. Med.
, vol.6
, pp. 1235-1240
-
-
Cheng, T.1
Rodrigues, N.2
Dombkowski, D.3
Stier, S.4
Scadden, D.T.5
-
18
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T., Rodrigues N., Shen H., Yang Y., Dombkowski D., Sykes M., and Scadden D.T. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287 (2000) 1804-1808
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
Yang, Y.4
Dombkowski, D.5
Sykes, M.6
Scadden, D.T.7
-
19
-
-
0028364374
-
Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
-
Davis R.J., D'Cruz C.M., Lovell M.A., Biegel J.A., and Barr F.G. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res. 54 (1994) 2869-2872
-
(1994)
Cancer Res.
, vol.54
, pp. 2869-2872
-
-
Davis, R.J.1
D'Cruz, C.M.2
Lovell, M.A.3
Biegel, J.A.4
Barr, F.G.5
-
20
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
Dijkers P.F., Medema R.H., Lammers J.W., Koenderman L., and Coffer P.J. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr. Biol. 10 (2000) 1201-1204
-
(2000)
Curr. Biol.
, vol.10
, pp. 1201-1204
-
-
Dijkers, P.F.1
Medema, R.H.2
Lammers, J.W.3
Koenderman, L.4
Coffer, P.J.5
-
21
-
-
0034677173
-
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential
-
Domen J., Cheshier S.H., and Weissman I.L. The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential. J. Exp. Med. 191 (2000) 253-264
-
(2000)
J. Exp. Med.
, vol.191
, pp. 253-264
-
-
Domen, J.1
Cheshier, S.H.2
Weissman, I.L.3
-
22
-
-
11244320393
-
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
-
Essers M.A., Weijzen S., de Vries-Smits A.M., Saarloos I., de Ruiter N.D., Bos J.L., and Burgering B.M. FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 23 (2004) 4802-4812
-
(2004)
EMBO J.
, vol.23
, pp. 4802-4812
-
-
Essers, M.A.1
Weijzen, S.2
de Vries-Smits, A.M.3
Saarloos, I.4
de Ruiter, N.D.5
Bos, J.L.6
Burgering, B.M.7
-
23
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers M.A., de Vries-Smits L.M., Barker N., Polderman P.E., Burgering B.M., and Korswagen H.C. Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 308 (2005) 1181-1184
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
de Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
24
-
-
20144365700
-
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
-
Frescas D., Valenti L., and Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J. Biol. Chem. 280 (2005) 20589-20595
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20589-20595
-
-
Frescas, D.1
Valenti, L.2
Accili, D.3
-
25
-
-
4544227785
-
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
-
Furuyama T., Kitayama K., Shimoda Y., Ogawa M., Sone K., Yoshida-Araki K., Hisatsune H., Nishikawa S., Nakayama K., Ikeda K., et al. Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J. Biol. Chem. 279 (2004) 34741-34749
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34741-34749
-
-
Furuyama, T.1
Kitayama, K.2
Shimoda, Y.3
Ogawa, M.4
Sone, K.5
Yoshida-Araki, K.6
Hisatsune, H.7
Nishikawa, S.8
Nakayama, K.9
Ikeda, K.10
-
26
-
-
0027521658
-
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
-
Galili N., Davis R.J., Fredericks W.J., Mukhopadhyay S., Rauscher III F.J., Emanuel B.S., Rovera G., and Barr F.G. Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat. Genet. 5 (1993) 230-235
-
(1993)
Nat. Genet.
, vol.5
, pp. 230-235
-
-
Galili, N.1
Davis, R.J.2
Fredericks, W.J.3
Mukhopadhyay, S.4
Rauscher III, F.J.5
Emanuel, B.S.6
Rovera, G.7
Barr, F.G.8
-
27
-
-
3142749712
-
Long-lived Drosophila with overexpressed dFOXO in adult fat body
-
Giannakou M.E., Goss M., Junger M.A., Hafen E., Leevers S.J., and Partridge L. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 305 (2004) 361
-
(2004)
Science
, vol.305
, pp. 361
-
-
Giannakou, M.E.1
Goss, M.2
Junger, M.A.3
Hafen, E.4
Leevers, S.J.5
Partridge, L.6
-
28
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer E.L., and Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24 (2005) 7410-7425
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
29
-
-
33751348056
-
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
-
Guertin D.A., Stevens D.M., Thoreen C.C., Burds A.A., Kalaany N.Y., Moffat J., Brown M., Fitzgerald K.J., and Sabatini D.M. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev. Cell 11 (2006) 859-871
-
(2006)
Dev. Cell
, vol.11
, pp. 859-871
-
-
Guertin, D.A.1
Stevens, D.M.2
Thoreen, C.C.3
Burds, A.A.4
Kalaany, N.Y.5
Moffat, J.6
Brown, M.7
Fitzgerald, K.J.8
Sabatini, D.M.9
-
30
-
-
16844363378
-
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
-
Guzman M.L., Rossi R.M., Karnischky L., Li X., Peterson D.R., Howard D.S., and Jordan C.T. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105 (2005) 4163-4169
-
(2005)
Blood
, vol.105
, pp. 4163-4169
-
-
Guzman, M.L.1
Rossi, R.M.2
Karnischky, L.3
Li, X.4
Peterson, D.R.5
Howard, D.S.6
Jordan, C.T.7
-
31
-
-
3342958797
-
The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins
-
Harrington L.S., Findlay G.M., Gray A., Tolkacheva T., Wigfield S., Rebholz H., Barnett J., Leslie N.R., Cheng S., Shepherd P.R., et al. The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins. J. Cell Biol. 166 (2004) 213-223
-
(2004)
J. Cell Biol.
, vol.166
, pp. 213-223
-
-
Harrington, L.S.1
Findlay, G.M.2
Gray, A.3
Tolkacheva, T.4
Wigfield, S.5
Rebholz, H.6
Barnett, J.7
Leslie, N.R.8
Cheng, S.9
Shepherd, P.R.10
-
32
-
-
0030869789
-
AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily
-
Hillion J., Le Coniat M., Jonveaux P., Berger R., and Bernard O.A. AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily. Blood 90 (1997) 3714-3719
-
(1997)
Blood
, vol.90
, pp. 3714-3719
-
-
Hillion, J.1
Le Coniat, M.2
Jonveaux, P.3
Berger, R.4
Bernard, O.A.5
-
33
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman M.F., Jacobs F.M., Smidt M.P., and Burbach J.P. Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr. Patterns 6 (2006) 134-140
-
(2006)
Gene Expr. Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
34
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Honda Y., and Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13 (1999) 1385-1393
-
(1999)
FASEB J.
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
35
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka T., Biggs III W.H., Tieu D., Boyer A.D., Varki N.M., Cavenee W.K., and Arden K.C. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc. Natl. Acad. Sci. USA 101 (2004) 2975-2980
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs III, W.H.2
Tieu, D.3
Boyer, A.D.4
Varki, N.M.5
Cavenee, W.K.6
Arden, K.C.7
-
36
-
-
0042477748
-
Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors
-
Hribal M.L., Nakae J., Kitamura T., Shutter J.R., and Accili D. Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. J. Cell Biol. 162 (2003) 535-541
-
(2003)
J. Cell Biol.
, vol.162
, pp. 535-541
-
-
Hribal, M.L.1
Nakae, J.2
Kitamura, T.3
Shutter, J.R.4
Accili, D.5
-
37
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu M.C., Lee D.F., Xia W., Golfman L.S., Ou-Yang F., Yang J.Y., Zou Y., Bao S., Hanada N., Saso H., et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117 (2004) 225-237
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
Lee, D.F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.Y.6
Zou, Y.7
Bao, S.8
Hanada, N.9
Saso, H.10
-
38
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
Huang P., Feng L., Oldham E.A., Keating M.J., and Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 407 (2000) 390-395
-
(2000)
Nature
, vol.407
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Keating, M.J.4
Plunkett, W.5
-
39
-
-
13444252337
-
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation
-
Huang H., Regan K.M., Wang F., Wang D., Smith D.I., van Deursen J.M., and Tindall D.J. Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation. Proc. Natl. Acad. Sci. USA 102 (2005) 1649-1654
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1649-1654
-
-
Huang, H.1
Regan, K.M.2
Wang, F.3
Wang, D.4
Smith, D.I.5
van Deursen, J.M.6
Tindall, D.J.7
-
40
-
-
4544324306
-
Blasts from the past: new lessons in stem cell biology from chronic myelogenous leukemia
-
Huntly B.J., and Gilliland D.G. Blasts from the past: new lessons in stem cell biology from chronic myelogenous leukemia. Cancer Cell 6 (2004) 199-201
-
(2004)
Cancer Cell
, vol.6
, pp. 199-201
-
-
Huntly, B.J.1
Gilliland, D.G.2
-
41
-
-
2942563805
-
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
-
Hwangbo D.S., Gershman B., Tu M.P., Palmer M., and Tatar M. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429 (2004) 562-566
-
(2004)
Nature
, vol.429
, pp. 562-566
-
-
Hwangbo, D.S.1
Gershman, B.2
Tu, M.P.3
Palmer, M.4
Tatar, M.5
-
42
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
Ito K., Hirao A., Arai F., Matsuoka S., Takubo K., Hamaguchi I., Nomiyama K., Hosokawa K., Sakurada K., Nakagata N., et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431 (2004) 997-1002
-
(2004)
Nature
, vol.431
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
-
43
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K., Hirao A., Arai F., Takubo K., Matsuoka S., Miyamoto K., Ohmura M., Naka K., Hosokawa K., Ikeda Y., and Suda T. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 12 (2006) 446-451
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
44
-
-
33749172559
-
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
-
Janzen V., Forkert R., Fleming H.E., Saito Y., Waring M.T., Dombkowski D.M., Cheng T., DePinho R.A., Sharpless N.E., and Scadden D.T. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature 443 (2006) 421-426
-
(2006)
Nature
, vol.443
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.E.3
Saito, Y.4
Waring, M.T.5
Dombkowski, D.M.6
Cheng, T.7
DePinho, R.A.8
Sharpless, N.E.9
Scadden, D.T.10
-
45
-
-
20944443597
-
Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
-
Jonsson H., Allen P., and Peng S.L. Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis. Nat. Med. 11 (2005) 666-671
-
(2005)
Nat. Med.
, vol.11
, pp. 666-671
-
-
Jonsson, H.1
Allen, P.2
Peng, S.L.3
-
46
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
Kau T.R., Schroeder F., Ramaswamy S., Wojciechowski C.L., Zhao J.J., Roberts T.M., Clardy J., Sellers W.R., and Silver P.A. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell 4 (2003) 463-476
-
(2003)
Cancer Cell
, vol.4
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
Wojciechowski, C.L.4
Zhao, J.J.5
Roberts, T.M.6
Clardy, J.7
Sellers, W.R.8
Silver, P.A.9
-
47
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
48
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim C.F., Jackson E.L., Woolfenden A.E., Lawrence S., Babar I., Vogel S., Crowley D., Bronson R.T., and Jacks T. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121 (2005) 823-835
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
Lawrence, S.4
Babar, I.5
Vogel, S.6
Crowley, D.7
Bronson, R.T.8
Jacks, T.9
-
49
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops G.J., Dansen T.B., Polderman P.E., Saarloos I., Wirtz K.W., Coffer P.J., Huang T.T., Bos J.L., Medema R.H., and Burgering B.M. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419 (2002) 316-321
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
50
-
-
0036120725
-
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors
-
Kops G.J., Medema R.H., Glassford J., Essers M.A., Dijkers P.F., Coffer P.J., Lam E.W., and Burgering B.M. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol. Cell. Biol. 22 (2002) 2025-2036
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2025-2036
-
-
Kops, G.J.1
Medema, R.H.2
Glassford, J.3
Essers, M.A.4
Dijkers, P.F.5
Coffer, P.J.6
Lam, E.W.7
Burgering, B.M.8
-
51
-
-
4444307411
-
Mouse development and cell proliferation in the absence of D-cyclins
-
Kozar K., Ciemerych M.A., Rebel V.I., Shigematsu H., Zagozdzon A., Sicinska E., Geng Y., Yu Q., Bhattacharya S., Bronson R.T., et al. Mouse development and cell proliferation in the absence of D-cyclins. Cell 118 (2004) 477-491
-
(2004)
Cell
, vol.118
, pp. 477-491
-
-
Kozar, K.1
Ciemerych, M.A.2
Rebel, V.I.3
Shigematsu, H.4
Zagozdzon, A.5
Sicinska, E.6
Geng, Y.7
Yu, Q.8
Bhattacharya, S.9
Bronson, R.T.10
-
52
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen M.K., Yuan Z., Boag P.R., Yang Y., Villen J., Becker E.B., DiBacco S., de la Iglesia N., Gygi S., Blackwell T.K., and Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125 (2006) 987-1001
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
DiBacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
Bonni, A.11
-
53
-
-
4143129696
-
Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a
-
Lin L., Hron J.D., and Peng S.L. Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. Immunity 21 (2004) 203-213
-
(2004)
Immunity
, vol.21
, pp. 203-213
-
-
Lin, L.1
Hron, J.D.2
Peng, S.L.3
-
54
-
-
2342653278
-
Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead
-
Martinez-Gac L., Marques M., Garcia Z., Campanero M.R., and Carrera A.C. Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead. Mol. Cell. Biol. 24 (2004) 2181-2189
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2181-2189
-
-
Martinez-Gac, L.1
Marques, M.2
Garcia, Z.3
Campanero, M.R.4
Carrera, A.C.5
-
55
-
-
0141706357
-
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
-
Matsuzaki H., Daitoku H., Hatta M., Tanaka K., and Fukamizu A. Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation. Proc. Natl. Acad. Sci. USA 100 (2003) 11285-11290
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11285-11290
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Tanaka, K.4
Fukamizu, A.5
-
56
-
-
23844485211
-
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
-
Matsuzaki H., Daitoku H., Hatta M., Aoyama H., Yoshimochi K., and Fukamizu A. Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. Proc. Natl. Acad. Sci. USA 102 (2005) 11278-11283
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11278-11283
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Aoyama, H.4
Yoshimochi, K.5
Fukamizu, A.6
-
57
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema R.H., Kops G.J., Bos J.L., and Burgering B.M. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404 (2000) 782-787
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
58
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K.A., Araki K.Y., Naka K., Arai F., Takubo K., Yamazaki S., Matsuoka S., Miyamoto T., Ito K., Ohmura M., et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1 (2007) 101-112
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.A.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
Yamazaki, S.6
Matsuoka, S.7
Miyamoto, T.8
Ito, K.9
Ohmura, M.10
-
59
-
-
0037033005
-
FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
-
Modur V., Nagarajan R., Evers B.M., and Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J. Biol. Chem. 277 (2002) 47928-47937
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47928-47937
-
-
Modur, V.1
Nagarajan, R.2
Evers, B.M.3
Milbrandt, J.4
-
60
-
-
0037237279
-
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
-
Nakae J., Kitamura T., Kitamura Y., Biggs III W.H., Arden K.C., and Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev. Cell 4 (2003) 119-129
-
(2003)
Dev. Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
Kitamura, T.2
Kitamura, Y.3
Biggs III, W.H.4
Arden, K.C.5
Accili, D.6
-
61
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
Nemoto S., and Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 295 (2002) 2450-2452
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
62
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto S., Fergusson M.M., and Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 306 (2004) 2105-2108
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
63
-
-
31744438846
-
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
-
Oh S.W., Mukhopadhyay A., Dixit B.L., Raha T., Green M.R., and Tissenbaum H.A. Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat. Genet. 38 (2006) 251-257
-
(2006)
Nat. Genet.
, vol.38
, pp. 251-257
-
-
Oh, S.W.1
Mukhopadhyay, A.2
Dixit, B.L.3
Raha, T.4
Green, M.R.5
Tissenbaum, H.A.6
-
64
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik J.H., Kollipara R., Chu G., Ji H., Xiao Y., Ding Z., Miao L., Tothova Z., Horner J.W., Carrasco D.R., et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 128 (2007) 309-323
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
Miao, L.7
Tothova, Z.8
Horner, J.W.9
Carrasco, D.R.10
-
65
-
-
0027959091
-
Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family
-
Parry P., Wei Y., and Evans G. Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family. Genes Chromosomes Cancer 11 (1994) 79-84
-
(1994)
Genes Chromosomes Cancer
, vol.11
, pp. 79-84
-
-
Parry, P.1
Wei, Y.2
Evans, G.3
-
66
-
-
0038362751
-
Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
-
Plas D.R., and Thompson C.B. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J. Biol. Chem. 278 (2003) 12361-12366
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12361-12366
-
-
Plas, D.R.1
Thompson, C.B.2
-
67
-
-
15544381570
-
Self-renewal and cancer of the gut: two sides of a coin
-
Radtke F., and Clevers H. Self-renewal and cancer of the gut: two sides of a coin. Science 307 (2005) 1904-1909
-
(2005)
Science
, vol.307
, pp. 1904-1909
-
-
Radtke, F.1
Clevers, H.2
-
68
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
-
Ramaswamy S., Nakamura N., Sansal I., Bergeron L., and Sellers W.R. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2 (2002) 81-91
-
(2002)
Cancer Cell
, vol.2
, pp. 81-91
-
-
Ramaswamy, S.1
Nakamura, N.2
Sansal, I.3
Bergeron, L.4
Sellers, W.R.5
-
69
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
Reynolds B.A., and Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255 (1992) 1707-1710
-
(1992)
Science
, vol.255
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
70
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri M., Sandri C., Gilbert A., Skurk C., Calabria E., Picard A., Walsh K., Schiaffino S., Lecker S.H., and Goldberg A.L. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117 (2004) 399-412
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skurk, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
71
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov D.D., Ali S.M., Sengupta S., Sheen J.H., Hsu P.P., Bagley A.F., Markhard A.L., and Sabatini D.M. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell 22 (2006) 159-168
-
(2006)
Mol. Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
72
-
-
1642332084
-
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J., Le H.V., Shen L., Anderson S.A., and Massague J. Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 117 (2004) 211-223
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le, H.V.2
Shen, L.3
Anderson, S.A.4
Massague, J.5
-
73
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt T.N., Drujan D., Clarke B.A., Panaro F., Timofeyva Y., Kline W.O., Gonzalez M., Yancopoulos G.D., and Glass D.J. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell 14 (2004) 395-403
-
(2004)
Mol. Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.4
Timofeyva, Y.5
Kline, W.O.6
Gonzalez, M.7
Yancopoulos, G.D.8
Glass, D.J.9
-
74
-
-
84956427297
-
A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
-
Till J.E., and McCulloch E.A. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat. Res. 14 (1961) 213-222
-
(1961)
Radiat. Res.
, vol.14
, pp. 213-222
-
-
Till, J.E.1
McCulloch, E.A.2
-
75
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z., Kollipara R., Huntly B.J., Lee B.H., Castrillon D.H., Cullen D.E., McDowell E.P., Lazo-Kallanian S., Williams I.R., Sears C., et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128 (2007) 325-339
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
Sears, C.10
-
76
-
-
0037134040
-
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
-
Tran H., Brunet A., Grenier J.M., Datta S.R., Fornace Jr. A.J., DiStefano P.S., Chiang L.W., and Greenberg M.E. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296 (2002) 530-534
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
Datta, S.R.4
Fornace Jr., A.J.5
DiStefano, P.S.6
Chiang, L.W.7
Greenberg, M.E.8
-
77
-
-
27744432642
-
FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttling
-
van der Heide L.P., Jacobs F.M., Burbach J.P., Hoekman M.F., and Smidt M.P. FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttling. Biochem. J. 391 (2005) 623-629
-
(2005)
Biochem. J.
, vol.391
, pp. 623-629
-
-
van der Heide, L.P.1
Jacobs, F.M.2
Burbach, J.P.3
Hoekman, M.F.4
Smidt, M.P.5
-
78
-
-
34249281690
-
Stressing the role of FoxO proteins in lifespan and disease
-
van der Horst A., and Burgering B.M. Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 8 (2007) 440-450
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 440-450
-
-
van der Horst, A.1
Burgering, B.M.2
-
79
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
-
van der Horst A., Tertoolen L.G., de Vries-Smits L.M., Frye R.A., Medema R.H., and Burgering B.M. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J. Biol. Chem. 279 (2004) 28873-28879
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28873-28879
-
-
van der Horst, A.1
Tertoolen, L.G.2
de Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
80
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
van der Horst A., de Vries-Smits A.M., Brenkman A.B., van Triest M.H., van den Broek N., Colland F., Maurice M.M., and Burgering B.M. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 8 (2006) 1064-1073
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1064-1073
-
-
van der Horst, A.1
de Vries-Smits, A.M.2
Brenkman, A.B.3
van Triest, M.H.4
van den Broek, N.5
Colland, F.6
Maurice, M.M.7
Burgering, B.M.8
-
81
-
-
34147210988
-
Hydrogen Peroxide Sensing and Signaling
-
Veal E.A., Day A.M., and Morgan B.A. Hydrogen Peroxide Sensing and Signaling. Mol. Cell 26 (2007) 1-14
-
(2007)
Mol. Cell
, vol.26
, pp. 1-14
-
-
Veal, E.A.1
Day, A.M.2
Morgan, B.A.3
-
82
-
-
25444442080
-
Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins
-
Vogt P.K., Jiang H., and Aoki M. Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. Cell Cycle 4 (2005) 908-913
-
(2005)
Cell Cycle
, vol.4
, pp. 908-913
-
-
Vogt, P.K.1
Jiang, H.2
Aoki, M.3
-
83
-
-
17044408768
-
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
-
Wang M.C., Bohmann D., and Jasper H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121 (2005) 115-125
-
(2005)
Cell
, vol.121
, pp. 115-125
-
-
Wang, M.C.1
Bohmann, D.2
Jasper, H.3
-
84
-
-
33746069404
-
In control of biology: of mice, men and Foxes
-
Wijchers P.J., Burbach J.P., and Smidt M.P. In control of biology: of mice, men and Foxes. Biochem. J. 397 (2006) 233-246
-
(2006)
Biochem. J.
, vol.397
, pp. 233-246
-
-
Wijchers, P.J.1
Burbach, J.P.2
Smidt, M.P.3
-
85
-
-
33644750381
-
SMK-1, an essential regulator of DAF-16-mediated longevity
-
Wolff S., Ma H., Burch D., Maciel G.A., Hunter T., and Dillin A. SMK-1, an essential regulator of DAF-16-mediated longevity. Cell 124 (2006) 1039-1053
-
(2006)
Cell
, vol.124
, pp. 1039-1053
-
-
Wolff, S.1
Ma, H.2
Burch, D.3
Maciel, G.A.4
Hunter, T.5
Dillin, A.6
-
86
-
-
34250372956
-
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
-
Yagoda N., von Rechenberg M., Zaganjor E., Bauer A.J., Yang W.S., Fridman D.J., Wolpaw A.J., Smukste I., Peltier J.M., Boniface J.J., et al. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 447 (2007) 864-868
-
(2007)
Nature
, vol.447
, pp. 864-868
-
-
Yagoda, N.1
von Rechenberg, M.2
Zaganjor, E.3
Bauer, A.J.4
Yang, W.S.5
Fridman, D.J.6
Wolpaw, A.J.7
Smukste, I.8
Peltier, J.M.9
Boniface, J.J.10
-
87
-
-
33747613351
-
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
-
Yamazaki S., Iwama A., Takayanagi S., Morita Y., Eto K., Ema H., and Nakauchi H. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25 (2006) 3515-3523
-
(2006)
EMBO J.
, vol.25
, pp. 3515-3523
-
-
Yamazaki, S.1
Iwama, A.2
Takayanagi, S.3
Morita, Y.4
Eto, K.5
Ema, H.6
Nakauchi, H.7
-
88
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang Y., Hou H., Haller E.M., Nicosia S.V., and Bai W. Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO J. 24 (2005) 1021-1032
-
(2005)
EMBO J.
, vol.24
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
89
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., and Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
90
-
-
22844438667
-
Crosstalk between p53 and FOXO transcription factors
-
You H., and Mak T.W. Crosstalk between p53 and FOXO transcription factors. Cell Cycle 4 (2005) 37-38
-
(2005)
Cell Cycle
, vol.4
, pp. 37-38
-
-
You, H.1
Mak, T.W.2
-
91
-
-
34147146014
-
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML
-
Zeng Z., Sarbassov dos D., Samudio I.J., Yee K.W., Munsell M.F., Ellen Jackson C., Giles F.J., Sabatini D.M., Andreeff M., and Konopleva M. Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. Blood 109 (2007) 3509-3512
-
(2007)
Blood
, vol.109
, pp. 3509-3512
-
-
Zeng, Z.1
Sarbassov dos, D.2
Samudio, I.J.3
Yee, K.W.4
Munsell, M.F.5
Ellen Jackson, C.6
Giles, F.J.7
Sabatini, D.M.8
Andreeff, M.9
Konopleva, M.10
-
92
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J., Grindley J.C., Yin T., Jayasinghe S., He X.C., Ross J.T., Haug J.S., Rupp D., Porter-Westpfahl K.S., Wiedemann L.M., et al. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441 (2006) 518-522
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
Haug, J.S.7
Rupp, D.8
Porter-Westpfahl, K.S.9
Wiedemann, L.M.10
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