Mitochondria "fuel" breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

Cell Cycle

Volumn 11, Issue 23, 2012, Pages 4390-4401

  Sotgia, Federica ^a,b   Whitaker Menezes, Diana ^a   Martinez Outschoorn, Ubaldo E ^a,c   Salem, Ahmed F ^a   Tsirigos, Aristotelis ^d   Lamb, Rebecca ^b   Sneddon, Sharon ^b   Hulit, James ^b   Howell, Anthony ^b   Lisanti, Michael P ^a,b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

Cancer metabolism; Metabolic reprogramming; Mitochondria; Mitochondrial biogenesis; Mitochondrial translation; Oxidative phosphorylation (OXPHOS); Two compartment tumor metabolism

Indexed keywords

BIOCHEMICAL MARKER; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MONOCARBOXYLATE TRANSPORTER 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN AKAP1; PROTEIN GOLPH3; PROTEIN GOLPH3L; PROTEIN MRPL40; PROTEIN MRPS15; PROTEIN MRPS22; PROTEIN MRPS7; PROTEIN POLRMT; PROTEIN TIMM9; PROTEIN TOMM70A; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; BREAST CANCER; BREAST EPITHELIUM; CANCER PATIENT; CELL COMPARTMENTALIZATION; CELL LABELING; EPITHELIUM CELL; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIPOGENESIS; MITOCHONDRIAL RESPIRATION; STROMA CELL; UPREGULATION; VALIDATION PROCESS;

EID: 84870886414     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.22777     Document Type: Article

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