The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis

Molecular and Cellular Biology

Volumn 29, Issue 18, 2009, Pages 5070-5083

  Guo, Shaodong ^a   Copps, Kyle D ^a   Dong, Xiaocheng ^a   Park, Sunmin ^a   Cheng, Zhiyong ^a   Pocai, Alessandro ^b   Rossetti, Luciano ^b   Sajan, Mini ^c   Farese, Robert V ^c   White, Morris F ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PROTEIN IRS1; PROTEIN IRS2; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, MOUSE; IRS2 PROTEIN, MOUSE; MESSENGER RNA;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDING; GENE CONTROL; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE TOLERANCE; HOMEOSTASIS; HYPERINSULINEMIA; INSULIN SENSITIVITY; LIPID DIET; METABOLIC DISORDER; METABOLIC REGULATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; DIET RESTRICTION; FEEDING BEHAVIOR; FOOD; GENE EXPRESSION REGULATION; GENETICS; HYPERINSULINISM; LIVER; METABOLISM; MOUSE MUTANT; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; FASTING; FEEDING BEHAVIOR; FOOD; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; HYPERINSULINISM; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; LIVER; MICE; MICE, KNOCKOUT; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 70249108137     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00138-09     Document Type: Article

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