Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro

Molecular and Cellular Biology

Volumn 27, Issue 3, 2007, Pages 912-925

  Pan, Yi ^a,b   Mansfield, Kyle D ^b,d   Bertozzi, Cara C ^b   Rudenko, Viktoriya ^b   Chan, Denise A ^c   Giaccia, Amato J ^c   Simon, M Celeste ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c STANFORD UNIVERSITY   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; HYBRID PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; MYXOTHIAZOL; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; REACTIVE OXYGEN METABOLITE; ROTENONE; TRICARBOXYLIC ACID; UBIQUITIN PROTEIN LIGASE; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CELL FREE SYSTEM; CELL HYPOXIA; CELLULAR STRESS RESPONSE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDROXYLATION; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MITOCHONDRION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STABILITY; REOXYGENATION;

ANIMALS; CARCINOMA, RENAL CELL; CELL HYPOXIA; ELECTRON TRANSPORT; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MITOCHONDRIA; MOLECULAR MIMICRY; OXIDATION-REDUCTION; PROCOLLAGEN-PROLINE DIOXYGENASE; PROLINE; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; THERMODYNAMICS; UNCOUPLING AGENTS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 33846630894     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01223-06     Document Type: Article

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