-
1
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
-
Filipowicz W, Bhattacharyya SN, Sonenberg N, (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9: 102-114.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
3
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB, (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
4
-
-
50849141708
-
MirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts
-
Hammell M, Long D, Zhang L, Lee A, Carmack CS, et al. (2008) mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nat Methods 5: 813-819.
-
(2008)
Nat Methods
, vol.5
, pp. 813-819
-
-
Hammell, M.1
Long, D.2
Zhang, L.3
Lee, A.4
Carmack, C.S.5
-
5
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
6
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37: 495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
-
7
-
-
14044251458
-
Human MicroRNA targets
-
John B, Enright AJ, Aravin A, Tuschl T, Sander C, et al. (2004) Human MicroRNA targets. PLoS Biol 2: e363.
-
(2004)
PLoS Biol
, vol.2
-
-
John, B.1
Enright, A.J.2
Aravin, A.3
Tuschl, T.4
Sander, C.5
-
9
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP, et al. (2008) The impact of microRNAs on protein output. Nature 455: 64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
-
10
-
-
79956337383
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J, Loedige I, Filipowicz W, The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet.
-
Nat Rev Genet
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
12
-
-
60149088848
-
Origins and Mechanisms of miRNAs and siRNAs
-
Carthew RW, Sontheimer EJ, (2009) Origins and Mechanisms of miRNAs and siRNAs. Cell 136: 642-655.
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
13
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, et al. (2008) Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 40: 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
Wentzel, E.A.4
Arking, D.E.5
-
14
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell PH, Dachs GU, Gleadle JM, Nicholls LG, Harris AL, et al. (1997) Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci U S A 94: 8104-8109.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
Nicholls, L.G.4
Harris, A.L.5
-
15
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL, (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
16
-
-
43649093915
-
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
-
Kaelin WG Jr, Ratcliffe PJ, (2008) Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 30: 393-402.
-
(2008)
Mol Cell
, vol.30
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
17
-
-
70649088040
-
HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery
-
Semenza GL, (2009) HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery. Curr Pharm Des 15: 3839-3843.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 3839-3843
-
-
Semenza, G.L.1
-
18
-
-
77952055154
-
HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers
-
Baba Y, Nosho K, Shima K, Irahara N, Chan AT, et al. HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers. Am J Pathol 176: 2292 2301.
-
Am J Pathol
, vol.176
, pp. 2292
-
-
Baba, Y.1
Nosho, K.2
Shima, K.3
Irahara, N.4
Chan, A.T.5
-
19
-
-
66149119317
-
Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis
-
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, et al. (2009) Hypoxia-inducible factor-1alpha and-2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br J Cancer 100: 1666-1673.
-
(2009)
Br J Cancer
, vol.100
, pp. 1666-1673
-
-
Rasheed, S.1
Harris, A.L.2
Tekkis, P.P.3
Turley, H.4
Silver, A.5
-
20
-
-
77950901310
-
Vascular responses to hypoxia and ischemia
-
Semenza GL, Vascular responses to hypoxia and ischemia. Arterioscler Thromb Vasc Biol 30: 648-652.
-
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 648-652
-
-
Semenza, G.L.1
-
21
-
-
67650135755
-
MiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA
-
Pandey DP, Picard D, (2009) miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. Mol Cell Biol 29: 3783-3790.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3783-3790
-
-
Pandey, D.P.1
Picard, D.2
-
22
-
-
77949617195
-
An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples
-
Xiong J, Yu D, Wei N, Fu H, Cai T, et al. An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples.Febs J 277: 1684-1694.
-
Febs J
, vol.277
, pp. 1684-1694
-
-
Xiong, J.1
Yu, D.2
Wei, N.3
Fu, H.4
Cai, T.5
-
23
-
-
77956338502
-
Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein
-
Xiong J, Du Q, Liang Z, Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene.
-
Oncogene
-
-
Xiong, J.1
Du, Q.2
Liang, Z.3
-
24
-
-
77950518701
-
Schaar DG Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression
-
Ting Y, Medina DJ, Strair RK, Schaar DG Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression. Biochem Biophys Res Commun 394: 606-611.
-
Biochem Biophys Res Commun
, vol.394
, pp. 606-611
-
-
Ting, Y.1
Medina, D.J.2
Strair, R.K.3
-
25
-
-
77956292550
-
R miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics
-
Bar N, Dikstein R, R miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics. PLoS One 5: e10859.
-
PLoS One
, vol.5
-
-
Bar, N.1
Dikstein, R.2
-
26
-
-
77952952216
-
MiR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide
-
Liu L, Jiang Y, Zhang H, Greenlee AR, Yu R, et al. miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicol In Vitro 24: 1168-1175.
-
Toxicol In Vitro
, vol.24
, pp. 1168-1175
-
-
Liu, L.1
Jiang, Y.2
Zhang, H.3
Greenlee, A.R.4
Yu, R.5
-
27
-
-
77953948708
-
Identification of the miR-106b∼25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
-
Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, et al. Identification of the miR-106b∼25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 3: ra29.
-
Sci Signal
, vol.3
-
-
Poliseno, L.1
Salmena, L.2
Riccardi, L.3
Fornari, A.4
Song, M.S.5
-
28
-
-
56649084972
-
Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
-
Iliopoulos D, Malizos KN, Oikonomou P, Tsezou A, (2008) Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One 3: e3740.
-
(2008)
PLoS One
, vol.3
-
-
Iliopoulos, D.1
Malizos, K.N.2
Oikonomou, P.3
Tsezou, A.4
-
29
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101: 2999-3004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
-
30
-
-
85013312416
-
Tumor angiogenesis: therapeutic implications
-
Folkman J, (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
31
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N, (2002) VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2: 795-803.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
32
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS, (2008) Tumor angiogenesis. N Engl J Med 358: 2039-2049.
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
33
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza GL, (2007) Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007.
-
(2007)
Sci STKE
, vol.2007
-
-
Semenza, G.L.1
-
34
-
-
77950905821
-
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
-
Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, et al. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis.Proc Natl Acad Sci U S A 107: 6334-6339.
-
Proc Natl Acad Sci U S A
, vol.107
, pp. 6334-6339
-
-
Yamakuchi, M.1
Lotterman, C.D.2
Bao, C.3
Hruban, R.H.4
Karim, B.5
-
35
-
-
77952507643
-
MiR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells
-
Cascio S, D'Andrea A, Ferla R, Surmacz E, Gulotta E, et al. miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells. J Cell Physiol 224: 242-249.
-
J Cell Physiol
, vol.224
, pp. 242-249
-
-
Cascio, S.1
D'Andrea, A.2
Ferla, R.3
Surmacz, E.4
Gulotta, E.5
-
36
-
-
70449602451
-
Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration
-
Lei Z, Li B, Yang Z, Fang H, Zhang GM, et al. (2009) Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One 4: e7629.
-
(2009)
PLoS One
, vol.4
-
-
Lei, Z.1
Li, B.2
Yang, Z.3
Fang, H.4
Zhang, G.M.5
-
37
-
-
54949154476
-
MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
-
Hua Z, Lv Q, Ye W, Wong CK, Cai G, et al. (2006) MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One 1: e116.
-
(2006)
PLoS One
, vol.1
-
-
Hua, Z.1
Lv, Q.2
Ye, W.3
Wong, C.K.4
Cai, G.5
|