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Volumn 1840, Issue 4, 2014, Pages 1441-1453

MicroRNAs as regulators of mitochondrial function: Role in cancer suppression

Author keywords

Cancer; MicroRNA; Mitochondrion; Reprogramming of metabolism; TCA cycle

Indexed keywords

MICRORNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RNA;

EID: 84895544208     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.09.002     Document Type: Review
Times cited : (66)

References (175)
  • 1
    • 84858776574 scopus 로고    scopus 로고
    • MicroRNAs in metabolism and metabolic disorders
    • V. Rottiers, and A.M. Näär MicroRNAs in metabolism and metabolic disorders Nat. Rev. Mol. Cell Biol. 13 2012 239 250
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 239-250
    • Rottiers, V.1    Näär, A.M.2
  • 2
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • J. Tsang, J. Zhu, and A. van Oudenaarden MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals Mol. Cell 26 2007 753 767
    • (2007) Mol. Cell , vol.26 , pp. 753-767
    • Tsang, J.1    Zhu, J.2    Van Oudenaarden, A.3
  • 3
    • 84858379476 scopus 로고    scopus 로고
    • MicroRNAs in stress signaling and human disease
    • J.T. Mendell, and E.N. Olson MicroRNAs in stress signaling and human disease Cell 148 2012 1172 1187
    • (2012) Cell , vol.148 , pp. 1172-1187
    • Mendell, J.T.1    Olson, E.N.2
  • 4
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • M.S. Ebert, and P.A. Sharp Roles for microRNAs in conferring robustness to biological processes Cell 149 2012 515 524
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 5
    • 62549157379 scopus 로고    scopus 로고
    • MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis
    • B.T. Kren, P.Y. Wong, A. Sarver, X. Zhang, Y. Zeng, and C.J. Steer MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis RNA Biol. 6 2009 65 72
    • (2009) RNA Biol. , vol.6 , pp. 65-72
    • Kren, B.T.1    Wong, P.Y.2    Sarver, A.3    Zhang, X.4    Zeng, Y.5    Steer, C.J.6
  • 6
    • 77956343851 scopus 로고    scopus 로고
    • Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions
    • Z. Bian, L.M. Li, R. Tang, D.X. Hou, X. Chen, C.Y. Zhang, and K. Zen Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions Cell Res. 20 2010 1076 1078
    • (2010) Cell Res. , vol.20 , pp. 1076-1078
    • Bian, Z.1    Li, L.M.2    Tang, R.3    Hou, D.X.4    Chen, X.5    Zhang, C.Y.6    Zen, K.7
  • 7
    • 84857546393 scopus 로고    scopus 로고
    • Control of mitochondrial activity by miRNAs
    • P. Li, J. Jiao, G. Gao, and B.S. Prabhakar Control of mitochondrial activity by miRNAs J. Cell. Biochem. 113 2012 1104 1110
    • (2012) J. Cell. Biochem. , vol.113 , pp. 1104-1110
    • Li, P.1    Jiao, J.2    Gao, G.3    Prabhakar, B.S.4
  • 9
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Y. Lee, K. Jeon, J.T. Lee, S. Kim, and V.N. Kim MicroRNA maturation: stepwise processing and subcellular localization EMBO J. 21 2002 4663 4670
    • (2002) EMBO J. , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 10
    • 38149071979 scopus 로고    scopus 로고
    • Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    • J.G. Ruby, A. Stark, W.K. Johnston, M. Kellis, D.P. Bartel, and E.C. Lai Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs Genome Res. 17 2007 1850 1864
    • (2007) Genome Res. , vol.17 , pp. 1850-1864
    • Ruby, J.G.1    Stark, A.2    Johnston, W.K.3    Kellis, M.4    Bartel, D.P.5    Lai, E.C.6
  • 11
    • 77951964981 scopus 로고    scopus 로고
    • Posttranscriptional regulation of microRNA biogenesis in animals
    • H. Siomi, and M.C. Siomi Posttranscriptional regulation of microRNA biogenesis in animals Mol. Cell 38 2010 323 332
    • (2010) Mol. Cell , vol.38 , pp. 323-332
    • Siomi, H.1    Siomi, M.C.2
  • 12
    • 58149097010 scopus 로고    scopus 로고
    • Posttranscriptional crossregulation between Drosha and DGCR8
    • V.N. Kim Posttranscriptional crossregulation between Drosha and DGCR8 Cell 136 2009 75 84
    • (2009) Cell , vol.136 , pp. 75-84
    • Kim, V.N.1
  • 14
    • 0036512117 scopus 로고    scopus 로고
    • Messenger-RNA-binding proteins and the messages they carry
    • G. Dreyfuss, V.N. Kim, and N. Kataoka Messenger-RNA-binding proteins and the messages they carry Nat. Rev. Mol. Cell Biol. 3 2002 195 205
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 195-205
    • Dreyfuss, G.1    Kim, V.N.2    Kataoka, N.3
  • 15
    • 0037154964 scopus 로고    scopus 로고
    • A conserved mRNA export machinery coupled to pre-mRNA splicing
    • R. Reed, and E. Hurt A conserved mRNA export machinery coupled to pre-mRNA splicing Cell 108 2002 523 531
    • (2002) Cell , vol.108 , pp. 523-531
    • Reed, R.1    Hurt, E.2
  • 16
    • 0033592896 scopus 로고    scopus 로고
    • Splicing is required for rapid and efficient mRNA export in metazoans
    • M.J. Luo, and R. Reed Splicing is required for rapid and efficient mRNA export in metazoans Proc. Natl. Acad. Sci. U. S. A. 96 1999 14937 14942
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 14937-14942
    • Luo, M.J.1    Reed, R.2
  • 17
    • 0035951432 scopus 로고    scopus 로고
    • Quality control of mRNA function
    • L.E. Maquat, and G.G. Carmichael Quality control of mRNA function Cell 104 2001 173 176
    • (2001) Cell , vol.104 , pp. 173-176
    • Maquat, L.E.1    Carmichael, G.G.2
  • 19
    • 0030924190 scopus 로고    scopus 로고
    • CRM1 is an export receptor for leucine-rich nuclear export signals
    • M. Fornerod, M. Ohno, M. Yoshida, and I.W. Mattaj CRM1 is an export receptor for leucine-rich nuclear export signals Cell 90 1997 1051 1060
    • (1997) Cell , vol.90 , pp. 1051-1060
    • Fornerod, M.1    Ohno, M.2    Yoshida, M.3    Mattaj, I.W.4
  • 20
    • 0030775693 scopus 로고    scopus 로고
    • Nuclear import of U snRNPs requires importin b
    • I. Palacios, M. Hetzer, S.A. Adam, and I.W. Mattaj Nuclear import of U snRNPs requires importin b EMBO J. 16 1997 6783 6792
    • (1997) EMBO J. , vol.16 , pp. 6783-6792
    • Palacios, I.1    Hetzer, M.2    Adam, S.A.3    Mattaj, I.W.4
  • 21
    • 0032189145 scopus 로고    scopus 로고
    • ModiÆcations of U2 snRNA are required for snRNP assembly and pre-mRNA splicing
    • Y.T. Yu, M.D. Shu, and J.A. Steitz ModiÆcations of U2 snRNA are required for snRNP assembly and pre-mRNA splicing EMBO J. 17 1998 5783 5795
    • (1998) EMBO J. , vol.17 , pp. 5783-5795
    • Yu, Y.T.1    Shu, M.D.2    Steitz, J.A.3
  • 22
    • 79751485564 scopus 로고    scopus 로고
    • The many faces of RNAi
    • R.F. Ketting The many faces of RNAi Dev. Cell 20 2011 148 161
    • (2011) Dev. Cell , vol.20 , pp. 148-161
    • Ketting, R.F.1
  • 23
    • 84867576189 scopus 로고    scopus 로고
    • MicroRNAs: Small but amazing, and their association with endothelin
    • M. von Brandenstein, C. Richter, and J.W. Fries MicroRNAs: small but amazing, and their association with endothelin Life Sci. 91 2012 475 489
    • (2012) Life Sci. , vol.91 , pp. 475-489
    • Von Brandenstein, M.1    Richter, C.2    Fries, J.W.3
  • 24
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • M.R. Fabian, N. Sonenberg, and W. Filipowicz Regulation of mRNA translation and stability by microRNAs Annu. Rev. Biochem. 79 2010 351 379
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 26
    • 33845295461 scopus 로고    scopus 로고
    • Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
    • A.K. Leung, J.M. Calabrese, and P.A. Sharp Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules Proc. Natl. Acad. Sci. U. S. A. 103 2006 18125 18130
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 18125-18130
    • Leung, A.K.1    Calabrese, J.M.2    Sharp, P.A.3
  • 27
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • J. Liu, M.A. Valencia-Sanchez, G.J. Hannon, and R. Parker MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies Nat. Cell Biol. 7 2005 719 723
    • (2005) Nat. Cell Biol. , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 28
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs microRNA nuclear import
    • H.W. Hwang, E.A. Wentzel, and J.T. Mendell A hexanucleotide element directs microRNA nuclear import Science 315 2007 97 100
    • (2007) Science , vol.315 , pp. 97-100
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 29
    • 77956278708 scopus 로고    scopus 로고
    • Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3′ trailers
    • J.Y. Liao, L.M. Ma, Y.H. Guo, Y.C. Zhang, H. Zhou, P. Shao, Y.Q. Chen, and L.H. Qu Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3′ trailers PLoS One 5 2010 e10563
    • (2010) PLoS One , vol.5 , pp. 10563
    • Liao, J.Y.1    Ma, L.M.2    Guo, Y.H.3    Zhang, Y.C.4    Zhou, H.5    Shao, P.6    Chen, Y.Q.7    Qu, L.H.8
  • 30
    • 56649122127 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells
    • T. Ohrt, J. Mutze, W. Staroske, L. Weinmann, J. Hock, K. Crell, G. Meister, and P. Schwille Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells Nucleic Acids Res. 36 2008 6439 6449
    • (2008) Nucleic Acids Res. , vol.36 , pp. 6439-6449
    • Ohrt, T.1    Mutze, J.2    Staroske, W.3    Weinmann, L.4    Hock, J.5    Crell, K.6    Meister, G.7    Schwille, P.8
  • 31
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • D.J. Gibbings, C. Ciaudo, M. Erhardt, and O. Voinnet Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity Nat. Cell Biol. 11 2009 1143 1149
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 33
    • 84864300017 scopus 로고    scopus 로고
    • MicroRNA involvement in human cancer
    • M.V. Iorio, and C.M. Croce MicroRNA involvement in human cancer Carcinogenesis 33 2012 1126 1133
    • (2012) Carcinogenesis , vol.33 , pp. 1126-1133
    • Iorio, M.V.1    Croce, C.M.2
  • 38
    • 21844449964 scopus 로고    scopus 로고
    • Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein
    • E. Maniataki, and Z. Mourelatos Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein RNA 11 2005 849 852
    • (2005) RNA , vol.11 , pp. 849-852
    • Maniataki, E.1    Mourelatos, Z.2
  • 41
    • 58149379604 scopus 로고    scopus 로고
    • MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons
    • A. Aschrafi, A.D. Schwechter, M.G. Mameza, O. Natera-Naranjo, A.E. Gioio, and B.B. Kaplan MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons J. Neurosci. 28 2008 12581 12590
    • (2008) J. Neurosci. , vol.28 , pp. 12581-12590
    • Aschrafi, A.1    Schwechter, A.D.2    Mameza, M.G.3    Natera-Naranjo, O.4    Gioio, A.E.5    Kaplan, B.B.6
  • 44
    • 0026712942 scopus 로고
    • Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man
    • E. Barth, G. Stämmler, B. Speiser, and J. Schaper Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man J. Mol. Cell. Cardiol. 24 1992 669 681
    • (1992) J. Mol. Cell. Cardiol. , vol.24 , pp. 669-681
    • Barth, E.1    Stämmler, G.2    Speiser, B.3    Schaper, J.4
  • 45
    • 40949126440 scopus 로고    scopus 로고
    • Mitochondrial complex III regulates hypoxic activation of HIF
    • T. Klimova, and N.S. Chandel Mitochondrial complex III regulates hypoxic activation of HIF Cell Death Differ. 15 2008 660 666
    • (2008) Cell Death Differ. , vol.15 , pp. 660-666
    • Klimova, T.1    Chandel, N.S.2
  • 46
    • 84887016887 scopus 로고    scopus 로고
    • Sensors, transmitters, and targets in mitochondrial oxygen shortage-hypoxia-inducible factor relay story
    • (in press)
    • N. Dehne, and B. Brüne Sensors, transmitters, and targets in mitochondrial oxygen shortage-hypoxia-inducible factor relay story Antioxid. Redox Signal. Sep 6 2012 (in press)
    • (2012) Antioxid. Redox Signal.
    • Dehne, N.1    Brüne, B.2
  • 48
    • 77952111459 scopus 로고    scopus 로고
    • MiR-210-micromanager of the hypoxia pathway
    • X. Huang, Q.T. Le, and A.J. Giaccia MiR-210-micromanager of the hypoxia pathway Trends Mol. Med. 16 2010 230 237
    • (2010) Trends Mol. Med. , vol.16 , pp. 230-237
    • Huang, X.1    Le, Q.T.2    Giaccia, A.J.3
  • 49
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • S.Y. Chan, Y.Y. Zhang, C. Hemann, C.E. Mahoney, J.L. Zweier, and J. Loscalzo MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2 Cell Metab. 10 2012 273 284
    • (2012) Cell Metab. , vol.10 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 50
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • S.Y. Chan, Y.Y. Zhang, C. Hemann, C.E. Mahoney, J.L. Zweier, and J. Loscalzo MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2 Cell Metab. 10 2009 273 284
    • (2009) Cell Metab. , vol.10 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 52
    • 34347227058 scopus 로고    scopus 로고
    • Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
    • G. Semenza Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1 Biochem. J. 405 2007 1 9
    • (2007) Biochem. J. , vol.405 , pp. 1-9
    • Semenza, G.1
  • 55
    • 0026619273 scopus 로고
    • Deviant energetic metabolism of glycolytic cancer cells
    • L.G. Baggetto Deviant energetic metabolism of glycolytic cancer cells Biochimie 174 1992 959 974
    • (1992) Biochimie , vol.174 , pp. 959-974
    • Baggetto, L.G.1
  • 56
    • 78149409465 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease
    • J. Ren, L. Pulakat, A. Whaley-Connell, and J.R. Sowers Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease J. Mol. Med. 88 2010 993 1001
    • (2010) J. Mol. Med. , vol.88 , pp. 993-1001
    • Ren, J.1    Pulakat, L.2    Whaley-Connell, A.3    Sowers, J.R.4
  • 58
    • 79959207992 scopus 로고    scopus 로고
    • Mitochondrial pathophysiology and type 2 diabetes mellitus
    • P.M. Garcia-Roves Mitochondrial pathophysiology and type 2 diabetes mellitus Arch. Physiol. Biochem. 117 2011 177 187
    • (2011) Arch. Physiol. Biochem. , vol.117 , pp. 177-187
    • Garcia-Roves, P.M.1
  • 59
    • 41949114990 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in insulin resistance
    • J. Kim, Y. Wei, and J.R. Sowers Role of mitochondrial dysfunction in insulin resistance Circ. Res. 102 2008 101 414
    • (2008) Circ. Res. , vol.102 , pp. 101-414
    • Kim, J.1    Wei, Y.2    Sowers, J.R.3
  • 60
    • 84860512005 scopus 로고    scopus 로고
    • Links between metabolism and cancer
    • C.V. Dang Links between metabolism and cancer Genes Dev. 26 2012 877 890
    • (2012) Genes Dev. , vol.26 , pp. 877-890
    • Dang, C.V.1
  • 62
    • 79960939388 scopus 로고    scopus 로고
    • MiRs with a sweet tooth
    • A.M. Näär MiRs with a sweet tooth Cell Metab. 14 2011 149 150
    • (2011) Cell Metab. , vol.14 , pp. 149-150
    • Näär, A.M.1
  • 64
    • 77957656146 scopus 로고    scopus 로고
    • MiR-378(*) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway
    • L.J. Eichner, M.C. Perry, C.R. Dufour, N. Bertos, M. Park, J. St Pierre, and V. Giguere MiR-378(*) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway Cell Metab. 12 2010 352 361
    • (2010) Cell Metab. , vol.12 , pp. 352-361
    • Eichner, L.J.1    Perry, M.C.2    Dufour, C.R.3    Bertos, N.4    Park, M.5    St Pierre, J.6    Giguere, V.7
  • 66
    • 79953048345 scopus 로고    scopus 로고
    • The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes
    • H.S. Ryu, S.Y. Park, D. Ma, J. Zhang, and W. Lee The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes PLoS One 6 2011 e17343
    • (2011) PLoS One , vol.6 , pp. 17343
    • Ryu, H.S.1    Park, S.Y.2    Ma, D.3    Zhang, J.4    Lee, W.5
  • 67
    • 84865006708 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits tumor cell growth and its expression level correlates with poor survival in non-small cell lung cancer patients
    • J. Yang, H. Lan, X. Huang, B. Liu, and Y. Tong MicroRNA-126 inhibits tumor cell growth and its expression level correlates with poor survival in non-small cell lung cancer patients PLoS One 7 2012 e42978
    • (2012) PLoS One , vol.7 , pp. 42978
    • Yang, J.1    Lan, H.2    Huang, X.3    Liu, B.4    Tong, Y.5
  • 69
    • 84856821006 scopus 로고    scopus 로고
    • Signal transduction by mitochondrial oxidants
    • T. Finkel Signal transduction by mitochondrial oxidants J. Biol. Chem. 287 2012 4434 4440
    • (2012) J. Biol. Chem. , vol.287 , pp. 4434-4440
    • Finkel, T.1
  • 71
    • 84866515571 scopus 로고    scopus 로고
    • MicroRNA-145 protects cardiomyocytes against hydrogen heroxide-induced apoptosis through targeting the mitochondria apoptotic pathway
    • R. Li, G. Yan, Q. Li, H. Sun, Y. Hu, J. Sun, and B. Xu MicroRNA-145 protects cardiomyocytes against hydrogen heroxide-induced apoptosis through targeting the mitochondria apoptotic pathway PLoS One 7 2012 e44907
    • (2012) PLoS One , vol.7 , pp. 44907
    • Li, R.1    Yan, G.2    Li, Q.3    Sun, H.4    Hu, Y.5    Sun, J.6    Xu, B.7
  • 72
    • 84864663987 scopus 로고    scopus 로고
    • MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells
    • R. Haque, E. Chun, J.C. Howell, T. Sengupta, D. Chen, and H. Kim MicroRNA-30b-mediated regulation of catalase expression in human ARPE-19 cells PLoS One 7 2012 e42542
    • (2012) PLoS One , vol.7 , pp. 42542
    • Haque, R.1    Chun, E.2    Howell, J.C.3    Sengupta, T.4    Chen, D.5    Kim, H.6
  • 73
    • 79960140833 scopus 로고    scopus 로고
    • MiR-335 and miR-34a promote renal senescence by suppressing mitochondrial antioxidative enzymes
    • X.Y. Bai, Y. Ma, R. Ding, B. Fu, S. Shi, and X.M. Chen miR-335 and miR-34a promote renal senescence by suppressing mitochondrial antioxidative enzymes J. Am. Soc. Nephrol. 22 2011 1252 1261
    • (2011) J. Am. Soc. Nephrol. , vol.22 , pp. 1252-1261
    • Bai, X.Y.1    Ma, Y.2    Ding, R.3    Fu, B.4    Shi, S.5    Chen, X.M.6
  • 75
    • 84869030015 scopus 로고    scopus 로고
    • Fusion and fission: Interlinked process critical for mitochondrial health
    • D.C. Chan Fusion and fission: interlinked process critical for mitochondrial health Annu. Rev. Genet. 46 2012 265 287
    • (2012) Annu. Rev. Genet. , vol.46 , pp. 265-287
    • Chan, D.C.1
  • 76
    • 84864307425 scopus 로고    scopus 로고
    • Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation
    • E.S. Blomain, and S.B. McMahon Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation Biochim. Biophys. Acta 1819 2012 1075 1079
    • (2012) Biochim. Biophys. Acta , vol.1819 , pp. 1075-1079
    • Blomain, E.S.1    McMahon, S.B.2
  • 78
    • 39549092425 scopus 로고    scopus 로고
    • A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis
    • A. Tanaka, and R.J. Youle A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis Mol. Cell 29 2008 409 410
    • (2008) Mol. Cell , vol.29 , pp. 409-410
    • Tanaka, A.1    Youle, R.J.2
  • 79
    • 84865544952 scopus 로고    scopus 로고
    • Mitochondrial fission, fusion, and stress
    • R.J. Youle, and A.M. van der Bliek Mitochondrial fission, fusion, and stress Science 337 2012 1062 1065
    • (2012) Science , vol.337 , pp. 1062-1065
    • Youle, R.J.1    Van Der Bliek, A.M.2
  • 80
    • 76749157966 scopus 로고    scopus 로고
    • MiR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
    • J. Li, S. Donath, Y. Li, D. Qin, B.S. Prabhakar, and P. Li MiR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway PLoS Genet. 6 2010 e1000795
    • (2010) PLoS Genet. , vol.6 , pp. 1000795
    • Li, J.1    Donath, S.2    Li, Y.3    Qin, D.4    Prabhakar, B.S.5    Li, P.6
  • 81
    • 84871342129 scopus 로고    scopus 로고
    • MicroRNA (miRNA)-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcriptional factor A (mtTFA) and forkhead box j3 (Foxj3)
    • H. Yamamoto, K. Morino, Y. Nishio, S. Ugi, T. Yoshizaki, A. Kashiwagi, and H. Maegawa MicroRNA (miRNA)-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcriptional factor A (mtTFA) and forkhead box j3 (Foxj3) Am. J. Physiol. 303 2012 E1419 E1427
    • (2012) Am. J. Physiol. , vol.303
    • Yamamoto, H.1    Morino, K.2    Nishio, Y.3    Ugi, S.4    Yoshizaki, T.5    Kashiwagi, A.6    Maegawa, H.7
  • 82
    • 51649124519 scopus 로고    scopus 로고
    • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
    • M. Kundu, T. Lindsten, C.Y. Yang, J. Wu, F. Zhao, J. Zhang, M.A. Selak, P.A. Ney, and C.B. Thompson Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation Blood 112 2008 1493 1502
    • (2008) Blood , vol.112 , pp. 1493-1502
    • Kundu, M.1    Lindsten, T.2    Yang, C.Y.3    Wu, J.4    Zhao, F.5    Zhang, J.6    Selak, M.A.7    Ney, P.A.8    Thompson, C.B.9
  • 83
    • 0036479052 scopus 로고    scopus 로고
    • Mitochondrial disappearance from cells: A clue to the role of autophagy in programmed cell death and disease?
    • A.M. Tolkovsky, L. Xue, G.C. Fletcher, and V. Borutaite Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease? Biochimie 84 2002 233 240
    • (2002) Biochimie , vol.84 , pp. 233-240
    • Tolkovsky, A.M.1    Xue, L.2    Fletcher, G.C.3    Borutaite, V.4
  • 84
    • 67650246357 scopus 로고    scopus 로고
    • Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
    • K. Okamoto, N. Kondo-Okamoto, and Y. Ohsumi Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy Dev. Cell 17 2009 87 97
    • (2009) Dev. Cell , vol.17 , pp. 87-97
    • Okamoto, K.1    Kondo-Okamoto, N.2    Ohsumi, Y.3
  • 85
    • 77951228508 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: Cell death or cell survival?
    • N.M. Mazure, and J. Pouyssegur Hypoxia-induced autophagy: cell death or cell survival? Curr. Opin. Cell Biol. 22 2010 177 180
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 177-180
    • Mazure, N.M.1    Pouyssegur, J.2
  • 87
    • 79959973301 scopus 로고    scopus 로고
    • MiR-204 regulates cardiomyocyte autophagy induced by ischemia-reperfusion through LC3-II
    • J. Xiao, X. Zhu, B. He, Y. Zhang, B. Kang, Z. Wang, and X. Ni MiR-204 regulates cardiomyocyte autophagy induced by ischemia-reperfusion through LC3-II J. Biomed. Sci. 18 2011 35
    • (2011) J. Biomed. Sci. , vol.18 , pp. 35
    • Xiao, J.1    Zhu, X.2    He, B.3    Zhang, Y.4    Kang, B.5    Wang, Z.6    Ni, X.7
  • 88
    • 69449097865 scopus 로고    scopus 로고
    • Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
    • H. Zhu, H. Wu, X. Liu, B. Li, Y. Chen, X. Ren, C.G. Liu, and J.M. Yang Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells Autophagy 5 2009 816 823
    • (2009) Autophagy , vol.5 , pp. 816-823
    • Zhu, H.1    Wu, H.2    Liu, X.3    Li, B.4    Chen, Y.5    Ren, X.6    Liu, C.G.7    Yang, J.M.8
  • 89
    • 84868627011 scopus 로고    scopus 로고
    • MicroRNA regulation of autophagy
    • L.B. Frankel, and A.H. Lund MicroRNA regulation of autophagy Carcinogenesis 33 2012 2018 2025
    • (2012) Carcinogenesis , vol.33 , pp. 2018-2025
    • Frankel, L.B.1    Lund, A.H.2
  • 91
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • J.G. Zhang, J.J. Wang, F. Zhao, Q. Liu, K. Jiang, and G.H. Yang MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC) Clin. Chim. Acta 411 2010 846 852
    • (2010) Clin. Chim. Acta , vol.411 , pp. 846-852
    • Zhang, J.G.1    Wang, J.J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5    Yang, G.H.6
  • 95
    • 76049083966 scopus 로고    scopus 로고
    • Reactive oxygen species, cellular redox systems, and apoptosis
    • M.L. Circu, and T.Y. Aw Reactive oxygen species, cellular redox systems, and apoptosis Free Radic. Biol. Med. 48 2010 749 762
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 749-762
    • Circu, M.L.1    Aw, T.Y.2
  • 96
    • 0032146987 scopus 로고    scopus 로고
    • Bcl-2-family proteins: The role of the BH3 domain in apoptosis
    • A. Kelekar, and C.B. Thompson Bcl-2-family proteins: the role of the BH3 domain in apoptosis Trends Cell Biol. 8 1998 324 330
    • (1998) Trends Cell Biol. , vol.8 , pp. 324-330
    • Kelekar, A.1    Thompson, C.B.2
  • 98
    • 84878845628 scopus 로고    scopus 로고
    • MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells
    • C.C. Chio, J.W. Lin, H.A. Cheng, W.T. Chiu, Y.H. Wang, J.J. Wang, C.H. Hsing, and R.M. Chen MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells Arch. Toxicol. 87 2013 459 468
    • (2013) Arch. Toxicol. , vol.87 , pp. 459-468
    • Chio, C.C.1    Lin, J.W.2    Cheng, H.A.3    Chiu, W.T.4    Wang, Y.H.5    Wang, J.J.6    Hsing, C.H.7    Chen, R.M.8
  • 99
    • 84858005054 scopus 로고    scopus 로고
    • MiR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes
    • Y.B. Ouyang, Y. Lu, S. Yue, and R.G. Giffard MiR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes Mitochondrion 12 2012 213 219
    • (2012) Mitochondrion , vol.12 , pp. 213-219
    • Ouyang, Y.B.1    Lu, Y.2    Yue, S.3    Giffard, R.G.4
  • 101
    • 84055191603 scopus 로고    scopus 로고
    • Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis
    • J.F. He, Y.M. Luo, X.H. Wan, and D. Jiang Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis J. Biochem. Mol. Toxicol. 25 2011 404 408
    • (2011) J. Biochem. Mol. Toxicol. , vol.25 , pp. 404-408
    • He, J.F.1    Luo, Y.M.2    Wan, X.H.3    Jiang, D.4
  • 102
    • 84855387995 scopus 로고    scopus 로고
    • MicroRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting Cyclin D1 and Bcl-2
    • J. Nie, L. Liu, W. Zheng, L. Chen, X. Wu, Y. Xu, X. Du, and W. Han MicroRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting Cyclin D1 and Bcl-2 Carcinogenesis 33 2012 220 225
    • (2012) Carcinogenesis , vol.33 , pp. 220-225
    • Nie, J.1    Liu, L.2    Zheng, W.3    Chen, L.4    Wu, X.5    Xu, Y.6    Du, X.7    Han, W.8
  • 104
    • 84861220123 scopus 로고    scopus 로고
    • Downregulation of BCL2 by miRNAs augments drug-induced apoptosis - A combined computational and experimental approach
    • R. Singh, and N. Saini Downregulation of BCL2 by miRNAs augments drug-induced apoptosis - a combined computational and experimental approach J. Cell Sci. 125 2012 1568 1578
    • (2012) J. Cell Sci. , vol.125 , pp. 1568-1578
    • Singh, R.1    Saini, N.2
  • 106
    • 84455194000 scopus 로고    scopus 로고
    • MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis
    • L. Shi, S. Zhang, K. Feng, F. Wu, Y. Wan, Z. Wang, J. Zhang, Y. Wang, W. Yan, Z. Fu, and Y. You MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis Int. J. Oncol. 40 2012 119 129
    • (2012) Int. J. Oncol. , vol.40 , pp. 119-129
    • Shi, L.1    Zhang, S.2    Feng, K.3    Wu, F.4    Wan, Y.5    Wang, Z.6    Zhang, J.7    Wang, Y.8    Yan, W.9    Fu, Z.10    You, Y.11
  • 107
    • 84863355999 scopus 로고    scopus 로고
    • Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways
    • C.W. Zeng, X.J. Zhang, K.Y. Lin, H. Ye, S.Y. Feng, H. Zhang, and Y.Q. Chen Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways Mol. Pharmacol. 81 2012 578 586
    • (2012) Mol. Pharmacol. , vol.81 , pp. 578-586
    • Zeng, C.W.1    Zhang, X.J.2    Lin, K.Y.3    Ye, H.4    Feng, S.Y.5    Zhang, H.6    Chen, Y.Q.7
  • 108
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • O. Warburg On respiratory impairment in cancer cells Science 124 1956 269 270
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 110
    • 84876693212 scopus 로고    scopus 로고
    • Regulation of glycolysis and the Warburg effect by estrogen-related receptors
    • Q. Cai, T. Lin, S. Kamarajugadda, and J. Lu Regulation of glycolysis and the Warburg effect by estrogen-related receptors Oncogene 32 2013 2079 2086
    • (2013) Oncogene , vol.32 , pp. 2079-2086
    • Cai, Q.1    Lin, T.2    Kamarajugadda, S.3    Lu, J.4
  • 112
    • 48149091757 scopus 로고    scopus 로고
    • Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: Association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis
    • Y. Kolev, H. Uetake, Y. Takagi, and K. Sugihara Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis Ann. Surg. Oncol. 15 2008 2336 2344
    • (2008) Ann. Surg. Oncol. , vol.15 , pp. 2336-2344
    • Kolev, Y.1    Uetake, H.2    Takagi, Y.3    Sugihara, K.4
  • 113
    • 70449673054 scopus 로고    scopus 로고
    • Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy
    • M.I. Koukourakis, A. Giatromanolaki, S. Winter, R. Leek, E. Sivridis, and A.L. Harris Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy Oncology 77 2009 285 292
    • (2009) Oncology , vol.77 , pp. 285-292
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Winter, S.3    Leek, R.4    Sivridis, E.5    Harris, A.L.6
  • 115
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • V.R. Fantin, J. St-Pierre, and P. Leder Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance Cancer Cell 9 2006 425 434
    • (2006) Cancer Cell , vol.9 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 117
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: A cancer hallmark even Warburg did not anticipate
    • P.S. Ward, and C.B. Thompson Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate Cancer Cell 21 2012 297 308
    • (2012) Cancer Cell , vol.21 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 119
    • 34547660196 scopus 로고    scopus 로고
    • FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
    • Z. Tothova, and D.G. Gilliland FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system Cell Stem Cell 1 2007 140 152
    • (2007) Cell Stem Cell , vol.1 , pp. 140-152
    • Tothova, Z.1    Gilliland, D.G.2
  • 122
    • 52249096359 scopus 로고    scopus 로고
    • The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
    • C. Guo, J.F. Sah, L. Beard, J.K. Willson, S.D. Markowitz, and K. Guda The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers Genes Chromosomes Cancer 47 2008 939 946
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 939-946
    • Guo, C.1    Sah, J.F.2    Beard, L.3    Willson, J.K.4    Markowitz, S.D.5    Guda, K.6
  • 125
    • 79953702227 scopus 로고    scopus 로고
    • Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2
    • N. Zhu, D. Zhang, H. Xie, Z. Zhou, H. Chen, T. Hu, Y. Bai, Y. Shen, W. Yuan, Q. Jing, and Y. Qin Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2 Mol. Cell. Biochem. 351 2011 157 164
    • (2011) Mol. Cell. Biochem. , vol.351 , pp. 157-164
    • Zhu, N.1    Zhang, D.2    Xie, H.3    Zhou, Z.4    Chen, H.5    Hu, T.6    Bai, Y.7    Shen, Y.8    Yuan, W.9    Jing, Q.10    Qin, Y.11
  • 127
    • 45549090182 scopus 로고    scopus 로고
    • Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
    • X.C. Dong, K.D. Copps, S. Guo, Y. Li, R. Kollipara, R.A. DePinho, and M.F. White Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation Cell Metab. 8 2008 65 76
    • (2008) Cell Metab. , vol.8 , pp. 65-76
    • Dong, X.C.1    Copps, K.D.2    Guo, S.3    Li, Y.4    Kollipara, R.5    Depinho, R.A.6    White, M.F.7
  • 129
    • 30544433533 scopus 로고    scopus 로고
    • ATP citrate lyase is an important component of cell growth and transformation
    • D.E. Bauer, G. Hatzivassiliou, F. Zhao, C. Andreadis, and C.B. Thompson ATP citrate lyase is an important component of cell growth and transformation Oncogene 24 2005 6314 6322
    • (2005) Oncogene , vol.24 , pp. 6314-6322
    • Bauer, D.E.1    Hatzivassiliou, G.2    Zhao, F.3    Andreadis, C.4    Thompson, C.B.5
  • 132
    • 84865313576 scopus 로고    scopus 로고
    • Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
    • F.V. Filipp, D.A. Scott, Z.A. Ronai, A.L. Osterman, and J.W. Smith Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells Pigment Cell Melanoma Res. 25 2012 375 383
    • (2012) Pigment Cell Melanoma Res. , vol.25 , pp. 375-383
    • Filipp, F.V.1    Scott, D.A.2    Ronai, Z.A.3    Osterman, A.L.4    Smith, J.W.5
  • 135
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • A.L. Kung, S. Wang, J.M. Klco, W.G. Kaelin, and D.M. Livingston Suppression of tumor growth through disruption of hypoxia-inducible transcription Nat. Med. 12 2000 1335 1340
    • (2000) Nat. Med. , vol.12 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin, W.G.4    Livingston, D.M.5
  • 136
    • 33746071114 scopus 로고    scopus 로고
    • P300 and p53 levels determine activation of HIF-1 downstream targets in invasive breast cancer
    • M.M. Vleugel, D. Shvarts, E. van der Wall, and P.J. van Diest p300 and p53 levels determine activation of HIF-1 downstream targets in invasive breast cancer Hum. Pathol. 37 2006 1085 1092
    • (2006) Hum. Pathol. , vol.37 , pp. 1085-1092
    • Vleugel, M.M.1    Shvarts, D.2    Van Der Wall, E.3    Van Diest, P.J.4
  • 137
    • 40949108800 scopus 로고    scopus 로고
    • Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation
    • L.E. Huang Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation Cell Death Differ. 15 2008 672 677
    • (2008) Cell Death Differ. , vol.15 , pp. 672-677
    • Huang, L.E.1
  • 138
    • 33745831238 scopus 로고    scopus 로고
    • Cytokines and hormones in the regulation of hypoxia inducible factor-1alpha (HIF-1alpha)
    • J. Zhou, and B. Brüne Cytokines and hormones in the regulation of hypoxia inducible factor-1alpha (HIF-1alpha) Cardiovasc. Hematol. Agents Med. Chem. 4 2006 189 197
    • (2006) Cardiovasc. Hematol. Agents Med. Chem. , vol.4 , pp. 189-197
    • Zhou, J.1    Brüne, B.2
  • 139
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: Upstream and downstream of cancer metabolism
    • G.L. Semenza HIF-1: upstream and downstream of cancer metabolism Curr. Opin. Genet. Dev. 20 2010 51 56
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 51-56
    • Semenza, G.L.1
  • 140
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • J.W. Kim, I. Tchernyshyov, G.L. Semenza, and C.V. Dang HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia Cell Metab. 3 2006 177 185
    • (2006) Cell Metab. , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 141
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • I. Papandreou, R.A. Cairns, L. Fontana, A.L. Lim, and N.C. Denko HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Cell Metab. 3 2006 187 197
    • (2006) Cell Metab. , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 143
    • 84864573730 scopus 로고    scopus 로고
    • MicroRNAs and the Warburg effect: New players in an old arena
    • P. Gao, L. Sun, X. He, Y. Cao, and H. Zhang MicroRNAs and the Warburg effect: new players in an old arena Curr. Gene Ther. 12 2012 285 291
    • (2012) Curr. Gene Ther. , vol.12 , pp. 285-291
    • Gao, P.1    Sun, L.2    He, X.3    Cao, Y.4    Zhang, H.5
  • 147
    • 33947520506 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: Possible links between cell metabolism and stabilization of HIF
    • P. Koivunen, M. Hirsilä, A.M. Remes, I.E. Hassinen, K.I. Kivirikko, and J. Myllyharju Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF J. Biol. Chem. 282 2007 4524 4532
    • (2007) J. Biol. Chem. , vol.282 , pp. 4524-4532
    • Koivunen, P.1    Hirsilä, M.2    Remes, A.M.3    Hassinen, I.E.4    Kivirikko, K.I.5    Myllyharju, J.6
  • 148
    • 0034682786 scopus 로고    scopus 로고
    • Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: A mechanism of O2 sensing
    • N.S. Chandel, D.S. McClintock, C.E. Feliciano, T.M. Wood, J.A. Melendez, A.M. Rodriguez, and P.T. Schumacker Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing J. Biol. Chem. 275 2000 25130 25138
    • (2000) J. Biol. Chem. , vol.275 , pp. 25130-25138
    • Chandel, N.S.1    McClintock, D.S.2    Feliciano, C.E.3    Wood, T.M.4    Melendez, J.A.5    Rodriguez, A.M.6    Schumacker, P.T.7
  • 149
    • 0034680825 scopus 로고    scopus 로고
    • The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
    • F.H. Agani, P. Pichiule, J.C. Chavez, and J.C. LaManna The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia J. Biol. Chem. 275 2000 35863 35867
    • (2000) J. Biol. Chem. , vol.275 , pp. 35863-35867
    • Agani, F.H.1    Pichiule, P.2    Chavez, J.C.3    Lamanna, J.C.4
  • 151
    • 33846630894 scopus 로고    scopus 로고
    • Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
    • Y. Pan, K.D. Mansfield, C.C. Bertozzi, V. Rudenko, D.A. Chan, A.J. Giaccia, and M.C. Simon Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro Mol. Cell. Biol. 27 2007 912 925
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 912-925
    • Pan, Y.1    Mansfield, K.D.2    Bertozzi, C.C.3    Rudenko, V.4    Chan, D.A.5    Giaccia, A.J.6    Simon, M.C.7
  • 153
    • 84881235291 scopus 로고    scopus 로고
    • The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond
    • N. Rohwer, C. Zasada, S. Kempa, and T. Cramer The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond Oncogene 32 2013 3569 3576
    • (2013) Oncogene , vol.32 , pp. 3569-3576
    • Rohwer, N.1    Zasada, C.2    Kempa, S.3    Cramer, T.4
  • 154
    • 0036528246 scopus 로고    scopus 로고
    • Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
    • K. Kondo, J. Klco, E. Nakamura, M. Lechpammer, and W.G. Jr Kaelin Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein Cancer Cell 1 2002 237 246
    • (2002) Cancer Cell , vol.1 , pp. 237-246
    • Kondo, K.1    Klco, J.2    Nakamura, E.3    Lechpammer, M.4    Kaelin Jr., W.G.5
  • 155
    • 48649102010 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
    • A. Taguchi, K. Yanagisawa, M. Tanaka, K. Cao, Y. Matsuyama, H. Goto, and T. Takahashi Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster Cancer Res. 68 2008 5540 5545
    • (2008) Cancer Res. , vol.68 , pp. 5540-5545
    • Taguchi, A.1    Yanagisawa, K.2    Tanaka, M.3    Cao, K.4    Matsuyama, Y.5    Goto, H.6    Takahashi, T.7
  • 157
    • 70449602451 scopus 로고    scopus 로고
    • Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration
    • Z. Lei, B. Li, Z. Yang, H. Fang, G.M. Zhang, Z.H. Feng, and B. Huang Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration PLoS One 4 2009 e7629
    • (2009) PLoS One , vol.4 , pp. 7629
    • Lei, Z.1    Li, B.2    Yang, Z.3    Fang, H.4    Zhang, G.M.5    Feng, Z.H.6    Huang, B.7
  • 158
    • 79956359793 scopus 로고    scopus 로고
    • MicroRNA-22 regulates hypoxia signaling in colon cancer cells
    • M. Yamakuchi, S. Yagi, T. Ito, and C.J. Lowenstein MicroRNA-22 regulates hypoxia signaling in colon cancer cells PLoS One 6 2011 e20291
    • (2011) PLoS One , vol.6 , pp. 20291
    • Yamakuchi, M.1    Yagi, S.2    Ito, T.3    Lowenstein, C.J.4
  • 160
    • 84878830070 scopus 로고    scopus 로고
    • MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α
    • Y.M. Yeh, C.M. Chuang, K.C. Chao, and L.H. Wang MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α Int. J. Cancer 133 2013 867 878
    • (2013) Int. J. Cancer , vol.133 , pp. 867-878
    • Yeh, Y.M.1    Chuang, C.M.2    Chao, K.C.3    Wang, L.H.4
  • 161
    • 57149142495 scopus 로고    scopus 로고
    • The impact of O2 availability on human cancer
    • J.A. Bertout, S.A. Patel, and M.C. Simon The impact of O2 availability on human cancer Nat. Rev. Cancer 8 2008 967 975
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 967-975
    • Bertout, J.A.1    Patel, S.A.2    Simon, M.C.3
  • 164
    • 33845447175 scopus 로고    scopus 로고
    • LOT1 (ZAC1/PLAGL1) and its family members: Mechanisms and functions
    • A. Abdollahi LOT1 (ZAC1/PLAGL1) and its family members: mechanisms and functions J. Cell. Physiol. 210 2007 16 25
    • (2007) J. Cell. Physiol. , vol.210 , pp. 16-25
    • Abdollahi, A.1
  • 166
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
    • H. Zhang, P. Gao, R. Fukuda, G. Kumar, B. Krishnamachary, K.I. Zeller, C.V. Dang, and G.L. Semenza HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity Cancer Cell 11 2007 407 420
    • (2007) Cancer Cell , vol.11 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, C.V.7    Semenza, G.L.8
  • 168
    • 77956901498 scopus 로고    scopus 로고
    • The promise of microRNA replacement therapy
    • A.G. Bader, D. Brown, and M. Winkler The promise of microRNA replacement therapy Cancer Res. 70 2010 7027 7030
    • (2010) Cancer Res. , vol.70 , pp. 7027-7030
    • Bader, A.G.1    Brown, D.2    Winkler, M.3
  • 172
  • 175
    • 67649908891 scopus 로고    scopus 로고
    • MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2
    • Y. Tang, J. Zheng, Y. Sun, Z. Wu, Z. Liu, and G. Huang MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2 Int. Heart J. 50 2009 377 387
    • (2009) Int. Heart J. , vol.50 , pp. 377-387
    • Tang, Y.1    Zheng, J.2    Sun, Y.3    Wu, Z.4    Liu, Z.5    Huang, G.6


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