Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

EMBO Journal

Volumn 31, Issue 17, 2012, Pages 3513-3523

  Zhuang, Guanglei ^a   Wu, Xiumin ^a   Jiang, Zhaoshi ^a   Kasman, Ian ^a   Yao, Jenny ^a   Guan, Yinghui ^a   Oeh, Jason ^a   Modrusan, Zora ^a   Bais, Carlos ^a   Sampath, Deepak ^a   Ferrara, Napoleone ^a  

^a GENENTECH INC   (United States)

Author keywords

angiogenesis; endothelium; JAK STAT; microRNA; tumour

Indexed keywords

JANUS KINASE; MICRORNA 9; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 5; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL COMMUNICATION; CELL MIGRATION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; TUMOR CELL; TUMOR VASCULARIZATION;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOTHELIAL CELLS; HUMANS; JANUS KINASE 1; JANUS KINASE 2; MICE; MICE, INBRED BALB C; MICRORNAS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84866093563     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.183     Document Type: Article

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