The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational repression of IRS-1 in SK-Hep1 cells

Biochemical and Biophysical Research Communications

Volumn 434, Issue 3, 2013, Pages 503-508

  Jeong, Hyo Jin ^a   Park, Seung Yoon ^a   Yang, Won Mo ^a   Lee, Wan ^a  

^a Dongguk University College of Medicine   (South Korea)

Author keywords

Insulin resistance; IRS 1; MicroRNA; MiR 96; Mitochondrial dysfunction

Indexed keywords

INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MICRORNA; MICRORNA 96; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG; GLYCOGEN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; MIRN96 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; ASSAY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE TARGETING; GLYCOGEN SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RESISTANCE; METABOLIC INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; GENETICS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SYNTHESIS; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOGEN; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICRORNAS; MITOCHONDRIA; PROTEIN BIOSYNTHESIS; SIGNAL TRANSDUCTION; UP-REGULATION;

MLCS; MLOWN;

EID: 84880476558     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.104     Document Type: Article

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