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Volumn 114, Issue 5, 2013, Pages 967-974

HIFs, angiogenesis, and cancer

Author keywords

angiogenesis; cancer; hypoxia inducible factor 1 (HIF 1)

Indexed keywords

10 HYDROXYGLAUCANETIN; 4 [BIS(2 CHLOROETHYL)OXIDOAMINO]PHENYLALANINE; AMPHOTERICIN B; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANTINEOPLASTIC AGENT; APIGENIN; AW 464; BORTEZOMIB; CAMPTOTHECIN; CAULERPIN; CHETOCIN; CHETOMIN; CRYPTOPLEURINE; CURCUMIN; ECHINOMYCIN; EZN 2968; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; LIFICIGUAT; MANASSANTIN A; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR B; PLEUROTIN; RESVERATROL; SIBIRIQUINONE A; TRICHOSTATIN A; UNCLASSIFIED DRUG; VASCULOTROPIN; WORTMANNIN;

EID: 84875158140     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24438     Document Type: Article
Times cited : (171)

References (76)
  • 1
    • 1142273367 scopus 로고    scopus 로고
    • Angiogenesis in human cancer: Implications in cancer therapy
    • Bamias A, Dimopoulos MA,. 2003. Angiogenesis in human cancer: Implications in cancer therapy. Eur J Intern Med 14: 459-469.
    • (2003) Eur J Intern Med , vol.14 , pp. 459-469
    • Bamias, A.1    Dimopoulos, M.A.2
  • 2
    • 26244438912 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1: A novel target for cancer therapy
    • Belozerov VE, Van Meir EG,. 2005. Hypoxia inducible factor-1: A novel target for cancer therapy. Anticancer Drugs 16: 901-909.
    • (2005) Anticancer Drugs , vol.16 , pp. 901-909
    • Belozerov, V.E.1    Van Meir, E.G.2
  • 3
    • 0041465022 scopus 로고    scopus 로고
    • HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia
    • Berra E, Benizri E, Ginouves A, Volmat V, Roux D, Pouyssegur J,. 2003. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia. EMBO J 22: 4082-4090.
    • (2003) EMBO J , vol.22 , pp. 4082-4090
    • Berra, E.1    Benizri, E.2    Ginouves, A.3    Volmat, V.4    Roux, D.5    Pouyssegur, J.6
  • 4
    • 33747379469 scopus 로고    scopus 로고
    • Phenan-throquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells
    • Cai XF, Jin X, Lee D, Yang YT, Lee K, Hong YS, Lee JH, Lee JJ,. 2006. Phenan-throquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells. J Nat Prod 69: 1095-1097.
    • (2006) J Nat Prod , vol.69 , pp. 1095-1097
    • Cai, X.F.1    Jin, X.2    Lee, D.3    Yang, Y.T.4    Lee, K.5    Hong, Y.S.6    Lee, J.H.7    Lee, J.J.8
  • 5
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P,. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6: 389-395.
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 6
    • 0038204415 scopus 로고    scopus 로고
    • The diverse functions of histone acetyltransferase complexes
    • Carrozza MJ, Utley RT, Workman JL, Cote J,. 2003. The diverse functions of histone acetyltransferase complexes. Trends Genet 19: 321-329.
    • (2003) Trends Genet , vol.19 , pp. 321-329
    • Carrozza, M.J.1    Utley, R.T.2    Workman, J.L.3    Cote, J.4
  • 7
    • 33751162428 scopus 로고    scopus 로고
    • Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition
    • Choi H, Chun YS, Kim SW, Kim MS, Park JW,. 2006. Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition. Mol Pharmacol 70: 1664-1671.
    • (2006) Mol Pharmacol , vol.70 , pp. 1664-1671
    • Choi, H.1    Chun, Y.S.2    Kim, S.W.3    Kim, M.S.4    Park, J.W.5
  • 9
    • 34548098412 scopus 로고    scopus 로고
    • Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1
    • Dat NT, Jin XJ, Lee JH, Lee DH, Hong YS, Lee K, Kim YH, Lee JJ,. 2007. Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1. J Nat Prod 70: 1093-1097.
    • (2007) J Nat Prod , vol.70 , pp. 1093-1097
    • Dat, N.T.1    Jin, X.J.2    Lee, J.H.3    Lee, D.H.4    Hong, Y.S.5    Lee, K.6    Kim, Y.H.7    Lee, J.J.8
  • 10
    • 14644432362 scopus 로고    scopus 로고
    • Apigenin inhibits VEGF and HIF-1 expression via PI3K/Akt/p70S6K1 and HDM2/p53 pathways
    • Fang J, Xia C, Cao Z, Zheng JZ, Reed E, Jiang BH,. 2005. Apigenin inhibits VEGF and HIF-1 expression via PI3K/Akt/p70S6K1 and HDM2/p53 pathways. FASEB J 19: 342-353.
    • (2005) FASEB J , vol.19 , pp. 342-353
    • Fang, J.1    Xia, C.2    Cao, Z.3    Zheng, J.Z.4    Reed, E.5    Jiang, B.H.6
  • 11
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J,. 1990. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 13
    • 24744467401 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyl transferase inhibitor SCH66336 in human aerodigestive tract cancer
    • Han JY, Oh SH, Morgillo F, Myers JN, Kim E, Hong WK, Lee HY,. 2005. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyl transferase inhibitor SCH66336 in human aerodigestive tract cancer. J Natl Cancer Inst 97: 1272-1286.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1272-1286
    • Han, J.Y.1    Oh, S.H.2    Morgillo, F.3    Myers, J.N.4    Kim, E.5    Hong, W.K.6    Lee, H.Y.7
  • 14
    • 84865126339 scopus 로고    scopus 로고
    • Inhibition of ARNT severely compromises endothelial cell viability and function in response to moderate hypoxia
    • Han Y, Yang K, Proweller A, Zhou G, Jain MK, Ramirez-Bergeron DL,. 2012. Inhibition of ARNT severely compromises endothelial cell viability and function in response to moderate hypoxia. Angiogenesis 15: 409-420.
    • (2012) Angiogenesis , vol.15 , pp. 409-420
    • Han, Y.1    Yang, K.2    Proweller, A.3    Zhou, G.4    Jain, M.K.5    Ramirez-Bergeron, D.L.6
  • 15
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J,. 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353e64.
    • (1996) Cell , vol.86
    • Hanahan, D.1    Folkman, J.2
  • 16
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA,. 2000. The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 18
    • 33751192872 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia and hypoxia-inducible factors
    • Hickey MM, Simon MC,. 2006. Regulation of angiogenesis by hypoxia and hypoxia-inducible factors. Curr Top Dev Biol 76: 217-257.
    • (2006) Curr Top Dev Biol , vol.76 , pp. 217-257
    • Hickey, M.M.1    Simon, M.C.2
  • 20
    • 0036841843 scopus 로고    scopus 로고
    • Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol
    • Hur E, Kim HH, Choi SM, Kim JH, Yim S, Kwon HJ, Choi Y, Kim DK, Lee MO, Park H,. 2002. Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol. Mol Pharmacol 62: 975-982.
    • (2002) Mol Pharmacol , vol.62 , pp. 975-982
    • Hur, E.1    Kim, H.H.2    Choi, S.M.3    Kim, J.H.4    Yim, S.5    Kwon, H.J.6    Choi, Y.7    Kim, D.K.8    Lee, M.O.9    Park, H.10
  • 21
    • 33947214077 scopus 로고    scopus 로고
    • Chaetocin: A promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress
    • Isham CR, Tibodeau JD, Jin W, Xu R, Timm MM, Bible KC,. 2007. Chaetocin: A promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress. Blood 109: 2579-2588.
    • (2007) Blood , vol.109 , pp. 2579-2588
    • Isham, C.R.1    Tibodeau, J.D.2    Jin, W.3    Xu, R.4    Timm, M.M.5    Bible, K.C.6
  • 23
    • 38149015503 scopus 로고    scopus 로고
    • PI3K/PTEN signaling in tumorigenesis and angiogenesis
    • Jiang BH, Liu LZ,. 2008. PI3K/PTEN signaling in tumorigenesis and angiogenesis. Biochim Biophys Acta 1784: 150-158.
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 150-158
    • Jiang, B.H.1    Liu, L.Z.2
  • 24
    • 0030787469 scopus 로고    scopus 로고
    • Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
    • Jiang BH, Zheng JZ, Leung SW, Roe R, Semenza GL,. 1997. Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension. J Biol Chem 272: 19253-19260.
    • (1997) J Biol Chem , vol.272 , pp. 19253-19260
    • Jiang, B.H.1    Zheng, J.Z.2    Leung, S.W.3    Roe, R.4    Semenza, G.L.5
  • 25
    • 0034925041 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
    • Jiang BH, Jiang G, Zheng JZ, Lu Z, Hunter T, Vogt PK,. 2001. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ 12: 363-369.
    • (2001) Cell Growth Differ , vol.12 , pp. 363-369
    • Jiang, B.H.1    Jiang, G.2    Zheng, J.Z.3    Lu, Z.4    Hunter, T.5    Vogt, P.K.6
  • 26
    • 33749546461 scopus 로고    scopus 로고
    • Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding
    • Jones DT, Harris AL,. 2006. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding. Mol Cancer Ther 5: 2193-2202.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2193-2202
    • Jones, D.T.1    Harris, A.L.2
  • 27
    • 33749318557 scopus 로고    scopus 로고
    • Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor alpha expression but decrease functional transcriptional activity, DNA binding, and degradation
    • Jones DT, Pugh CW, Wigfield S,. 2006. Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor alpha expression but decrease functional transcriptional activity, DNA binding, and degradation. Clin Cancer Res 12: 5384-5394.
    • (2006) Clin Cancer Res , vol.12 , pp. 5384-5394
    • Jones, D.T.1    Pugh, C.W.2    Wigfield, S.3
  • 28
    • 0036718539 scopus 로고    scopus 로고
    • Molecular basis of the VHL hereditary cancer syndrome
    • Kaelin WG, Jr., 2002. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2: 673-682.
    • (2002) Nat Rev Cancer , vol.2 , pp. 673-682
    • Kaelin, Jr.W.G.1
  • 29
    • 22244440847 scopus 로고    scopus 로고
    • Proline hydroxylation and gene expression
    • Kaelin WG,. 2005. Proline hydroxylation and gene expression. Annu Rev Biochem 74: 115-128.
    • (2005) Annu Rev Biochem , vol.74 , pp. 115-128
    • Kaelin, W.G.1
  • 30
    • 33746496671 scopus 로고    scopus 로고
    • Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1a C-terminal activation domain
    • Kaluz S, Kaluzová M, Stanbridge EJ,. 2006. Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1a C-terminal activation domain. Mol Cell Biol 26: 5895-5907.
    • (2006) Mol Cell Biol , vol.26 , pp. 5895-5907
    • Kaluz, S.1    Kaluzová, M.2    Stanbridge, E.J.3
  • 33
    • 33644780111 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha
    • Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J,. 2006. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. Mol Cell Biol 26: 2019-2028.
    • (2006) Mol Cell Biol , vol.26 , pp. 2019-2028
    • Kong, X.1    Lin, Z.2    Liang, D.3    Fath, D.4    Sang, N.5    Caro, J.6
  • 34
    • 0042526053 scopus 로고    scopus 로고
    • Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; Analysis of RPTPmu gene expression using LacZ knock-in mice
    • Koop EA, Lopes SM, Feiken E, Bluyssen HA, van der Valk M, Voest EE, Mummery CL, Moolenaar WH, Gebbink MF,. 2003. Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTPmu gene expression using LacZ knock-in mice. Int J Dev Biol 47: 345-354.
    • (2003) Int J Dev Biol , vol.47 , pp. 345-354
    • Koop, E.A.1    Lopes, S.M.2    Feiken, E.3    Bluyssen, H.A.4    Van Der Valk, M.5    Voest, E.E.6    Mummery, C.L.7    Moolenaar, W.H.8    Gebbink, M.F.9
  • 37
    • 3142622930 scopus 로고    scopus 로고
    • Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
    • Kung AL, Zabludoff SD, France DS,. 2004b. Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway. Cancer Cell 6: 33-43.
    • (2004) Cancer Cell , vol.6 , pp. 33-43
    • Kung, A.L.1    Zabludoff, S.D.2    France, D.S.3
  • 38
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL,. 2001. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 21: 3995-4004.
    • (2001) Mol Cell Biol , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 40
    • 0037225763 scopus 로고    scopus 로고
    • Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1a activity
    • Lee YM, Kim SH, Kim HS, Jin SM, Nakajima H, Jeong KH, Kim KW,. 2003. Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1a activity. Biochem Biophys Res Commun 300: 241-246.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 241-246
    • Lee, Y.M.1    Kim, S.H.2    Kim, H.S.3    Jin, S.M.4    Nakajima, H.5    Jeong, K.H.6    Kim, K.W.7
  • 42
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor by hypoxia
    • Levy AP, Levy NS, Wegner S, Goldberg MA,. 1995. Transcriptional regulation of the rat vascular endothelial growth factor by hypoxia. J Biol Chem 270: 13333-13340.
    • (1995) J Biol Chem , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 43
    • 57749106966 scopus 로고    scopus 로고
    • A novel mode of action of YC-1 in HIF inhibition: Stimulation of FIH-dependent p300 dissociation from HIF-1a
    • Li SH, Shin DH, Chun YS, Lee MK, Kim MS, Park JW,. 2008. A novel mode of action of YC-1 in HIF inhibition: Stimulation of FIH-dependent p300 dissociation from HIF-1a. Mol Cancer Ther 7: 3729-3738.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3729-3738
    • Li, S.H.1    Shin, D.H.2    Chun, Y.S.3    Lee, M.K.4    Kim, M.S.5    Park, J.W.6
  • 46
    • 21644445092 scopus 로고    scopus 로고
    • Small molecule-mediated anti-cancer therapy via hypoxia-inducible factor-1 blockade
    • Macpherson GR, Figg WD,. 2004. Small molecule-mediated anti-cancer therapy via hypoxia-inducible factor-1 blockade. Cancer Biol Ther 3: 503-504.
    • (2004) Cancer Biol Ther , vol.3 , pp. 503-504
    • MacPherson, G.R.1    Figg, W.D.2
  • 49
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ,. 2001. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J 20: 5197-5206.
    • (2001) EMBO J , vol.20 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 50
    • 0037837724 scopus 로고    scopus 로고
    • Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex
    • Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M,. 2003. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. J Biol Chem 278: 11032-11040.
    • (2003) J Biol Chem , vol.278 , pp. 11032-11040
    • Maynard, M.A.1    Qi, H.2    Chung, J.3    Lee, E.H.4    Kondo, Y.5    Hara, S.6    Conaway, R.C.7    Conaway, J.W.8    Ohh, M.9
  • 52
    • 0033730355 scopus 로고    scopus 로고
    • A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence
    • Michel G, Minet E, Ernest I, Roland I, Durant F, Remacle J, Michiels C,. 2000. A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence. J Biomol Struct Dyn 18: 169-179.
    • (2000) J Biomol Struct Dyn , vol.18 , pp. 169-179
    • Michel, G.1    Minet, E.2    Ernest, I.3    Roland, I.4    Durant, F.5    Remacle, J.6    Michiels, C.7
  • 54
    • 74249111545 scopus 로고    scopus 로고
    • Ansamycin inhibitors of Hsp90: Nature's prototype for anti-chaperone therapy
    • Porter JR, Ge J, Lee J, Normant E, West K,. 2009. Ansamycin inhibitors of Hsp90: Nature's prototype for anti-chaperone therapy. Curr Top Med Chem 9: 1386-1418.
    • (2009) Curr Top Med Chem , vol.9 , pp. 1386-1418
    • Porter, J.R.1    Ge, J.2    Lee, J.3    Normant, E.4    West, K.5
  • 55
    • 33749006252 scopus 로고    scopus 로고
    • Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha
    • Qian DZ, Kachhap SK, Collis SJ, Verheul HMW, Carducci MA, Atadja P, Pili R,. 2006. Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha. Cancer Res 66: 8814-8821.
    • (2006) Cancer Res , vol.66 , pp. 8814-8821
    • Qian, D.Z.1    Kachhap, S.K.2    Collis, S.J.3    Verheul, H.M.W.4    Carducci, M.A.5    Atadja, P.6    Pili, R.7
  • 56
    • 1242271198 scopus 로고    scopus 로고
    • Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications
    • Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G,. 2004. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications. Cancer Res 64: 1475-1482.
    • (2004) Cancer Res , vol.64 , pp. 1475-1482
    • Rapisarda, A.1    Uranchimeg, B.2    Sordet, O.3    Pommier, Y.4    Shoemaker, R.H.5    Melillo, G.6
  • 58
    • 0037362890 scopus 로고    scopus 로고
    • HIF hydroxylation and the mammalian oxygen-sensing pathway
    • Safran M, Kaelin WG, Jr., 2003. HIF hydroxylation and the mammalian oxygen-sensing pathway. J Clin Invest 111: 779-783.
    • (2003) J Clin Invest , vol.111 , pp. 779-783
    • Safran, M.1    Kaelin, Jr.W.G.2
  • 59
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL,. 2003. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 60
    • 80755175776 scopus 로고    scopus 로고
    • Programmed cell death 6 (PDCD6) inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of VEGFR-2
    • Seung BR, Yong JS, Myong CL, Seung-Hoon L, Boh-Ram K, Sang-Yoon P,. 2012. Programmed cell death 6 (PDCD6) inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of VEGFR-2. Cell Signal 24: 131-139.
    • (2012) Cell Signal , vol.24 , pp. 131-139
    • Seung, B.R.1    Yong, J.S.2    Myong, C.L.3    Seung-Hoon, L.4    Boh-Ram, K.5    Sang-Yoon, P.6
  • 61
    • 75449104703 scopus 로고    scopus 로고
    • Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1a inhibitors
    • Shimizu K, Maruyama M, Yasui Y, Minegishi H, Ban HS, Nakamura H,. 2010. Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1a inhibitors. Bioorg Med Chem Lett 20: 1453-1456.
    • (2010) Bioorg Med Chem Lett , vol.20 , pp. 1453-1456
    • Shimizu, K.1    Maruyama, M.2    Yasui, Y.3    Minegishi, H.4    Ban, H.S.5    Nakamura, H.6
  • 62
    • 67651098992 scopus 로고    scopus 로고
    • Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis
    • [Epub 2009 May 13]
    • Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B,. 2009. Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Blood 114 (2): 469-477 [Epub 2009 May 13].
    • (2009) Blood , vol.114 , Issue.2 , pp. 469-477
    • Skuli, N.1    Liu, L.2    Runge, A.3    Wang, T.4    Yuan, L.5    Patel, S.6    Iruela-Arispe, L.7    Simon, M.C.8    Keith, B.9
  • 63
    • 7944224442 scopus 로고    scopus 로고
    • Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
    • Tang N, Wang L, Esko J, Giordano FJ, Huang Y, Gerber HP, Ferrara N, Johnson RS,. 2004. Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 6: 485-495.
    • (2004) Cancer Cell , vol.6 , pp. 485-495
    • Tang, N.1    Wang, L.2    Esko, J.3    Giordano, F.J.4    Huang, Y.5    Gerber, H.P.6    Ferrara, N.7    Johnson, R.S.8
  • 64
    • 0037008770 scopus 로고    scopus 로고
    • Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
    • Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E,. 2002. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 277: 27975-27981.
    • (2002) J Biol Chem , vol.277 , pp. 27975-27981
    • Treins, C.1    Giorgetti-Peraldi, S.2    Murdaca, J.3    Semenza, G.L.4    Van Obberghen, E.5
  • 65
    • 59649105538 scopus 로고    scopus 로고
    • Camptothecins: A SAR/QSAR study
    • Verma RP, Hansch C,. 2009. Camptothecins: A SAR/QSAR study. Chem Rev 109: 213-235.
    • (2009) Chem Rev , vol.109 , pp. 213-235
    • Verma, R.P.1    Hansch, C.2
  • 66
    • 33744829237 scopus 로고    scopus 로고
    • CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/HIF-1alpha/VEGF signaling
    • Wan X, Shen N, Mendoza A,. 2006. CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/HIF-1alpha/VEGF signaling. Neoplasia 8: 394-401.
    • (2006) Neoplasia , vol.8 , pp. 394-401
    • Wan, X.1    Shen, N.2    Mendoza, A.3
  • 67
    • 0347512126 scopus 로고    scopus 로고
    • Hypoxia inducible factor as a cancer drug target
    • Welsh SJ, Powis G,. 2003a. Hypoxia inducible factor as a cancer drug target. Curr Cancer Drug Targets 3: 391-405.
    • (2003) Curr Cancer Drug Targets , vol.3 , pp. 391-405
    • Welsh, S.J.1    Powis, G.2
  • 68
    • 0142144338 scopus 로고    scopus 로고
    • The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation
    • Welsh SJ, Williams RR, Birmingham A, Newman DJ, Kirkpatrick DL, Powis G,. 2003b. The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation. Mol Cancer Ther 2: 235-243.
    • (2003) Mol Cancer Ther , vol.2 , pp. 235-243
    • Welsh, S.J.1    Williams, R.R.2    Birmingham, A.3    Newman, D.J.4    Kirkpatrick, D.L.5    Powis, G.6
  • 70
    • 79955579927 scopus 로고    scopus 로고
    • HIF-1a inhibitors: Synthesis and biological evaluation of novel moracin O and P analogues
    • Xia Y, Jin YL, Kaur N, Choi Y, Lee K,. 2011. HIF-1a inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem 46: 2386-2396.
    • (2011) Eur J Med Chem , vol.46 , pp. 2386-2396
    • Xia, Y.1    Jin, Y.L.2    Kaur, N.3    Choi, Y.4    Lee, K.5
  • 71
    • 84862818535 scopus 로고    scopus 로고
    • Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
    • Yan X, Hyun-Kyung C, Kyeong L,. 2012. Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors. Eur J Med Chem 49: 24-40.
    • (2012) Eur J Med Chem , vol.49 , pp. 24-40
    • Yan, X.1    Hyun-Kyung, C.2    Kyeong, L.3
  • 72
    • 31544469773 scopus 로고    scopus 로고
    • Amphotericin B blunts erythropoietin response to hypoxia by reinforcing FIH-mediated repression of HIF-1
    • Yeo EJ, Ryu JH, Cho YS, Chun YS, Huang LE, Kim MS, Park JW,. 2006. Amphotericin B blunts erythropoietin response to hypoxia by reinforcing FIH-mediated repression of HIF-1. Blood 107: 916-923.
    • (2006) Blood , vol.107 , pp. 916-923
    • Yeo, E.J.1    Ryu, J.H.2    Cho, Y.S.3    Chun, Y.S.4    Huang, L.E.5    Kim, M.S.6    Park, J.W.7
  • 74
    • 27644508837 scopus 로고    scopus 로고
    • Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
    • Zhang Q, Tang X, Lu QY, Zhang ZF, Brown J, Le AD,. 2005. Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. Mol Cancer Ther 4: 1465-1474.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1465-1474
    • Zhang, Q.1    Tang, X.2    Lu, Q.Y.3    Zhang, Z.F.4    Brown, J.5    Le, A.D.6
  • 75
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL,. 2000. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 60: 1541-1545.
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8


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