Hot-melt extrusion-basic principles and pharmaceutical applications

Drug Development and Industrial Pharmacy

Volumn 40, Issue 9, 2014, Pages 1133-1155

  Lang, Bo ^a   McGinity, James W ^a   Williams III, Robert O ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Amorphous solid dispersion; Co crystal; Controlled release; Film; Implant; Melt extrusion; Polymer selection; Process development; Scale up

Indexed keywords

CARBOMER; CELLULOSE DERIVATIVE; EUDRAGIT; HYDROXYPROPYLCELLULOSE; MACROGOL; POLYLACTIC ACID; POLYMER; DRUG; DRUG DOSAGE FORM; EXCIPIENT;

CONTROLLED RELEASE FORMULATION; DISPERSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG GRANULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; GLASS TRANSITION TEMPERATURE; HEAT TRANSFER; HOT MELT EXTRUSION; HUMAN; MISCIBILITY; PARTICLE SIZE; PHASE SEPARATION; PHYSICAL CHEMISTRY; PROCESS DEVELOPMENT; REVIEW; SCALE UP; SPHERONIZATION; TENSILE STRENGTH; VISCOSITY; ANIMAL; CHEMISTRY; HEAT; MEDICINAL CHEMISTRY; PHARMACEUTICS; PROCEDURES;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; EXCIPIENTS; HOT TEMPERATURE; HUMANS; PHARMACEUTICAL PREPARATIONS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84906230783     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.838577     Document Type: Review

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